@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1290: (2016-03-23 )
MSVKSNIVKIGVCFAVLAVPVSQTTLPVFAAEQPGLKASQDNVNIPDSTFKAYLNGLLGQASTANITEAQMDSLTYITLANINVTDLTGIEYAHNIKDLTINNIHATNYNQISGLSNLERLRIMGADVTSDKIPNLSGLTNLTLLDLSHSAHDDSILTKINTLPKVTSIDLSYNGAITDIMPLKTMPELKSLNIQFDGVHDYRGIEDFPKLNTLLAYSQTIGGKKLINSDIKSSKLTYNAENQTLYVPFSLMTERTVNYDGYVPDFVKSTASSDTYFTMNEQQVNGNRLTITSDGLTVSDVSKTDFDNLEKMEYNARIDLSYQSYNTPEQFQNGGSYTISMPIYDHYFTVDHSLNITADSEKTYIENQLVTEATFLSDIHAKTDDGSTVTSDFADKVDFNTPGTYTVTLQSENNAGLKATPVQVNVTIKAKTTITADEKITYKVDTSKTEAAFLADIKATTNDGTAITSDFATVVDLSKPGKYVVTLNAENDLQKALPVQVMVIVEKETPIPDPTPTPTPDPTPTPDPSPTPNPVINPNVNKPEVPSYKIPSLTVNEKKAKAEPSKEALPKTGDSLPVAGATVGFLLIGLSWFVSRKK
Atome Classification :
(20 SA)
.........10........20........30........40........50........60-.-.-...-...70........80........90........100.......110.......120...-....130.......140.---......150.......160.......-170...-....180.......190.......200.......210..-.....220....--...230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MSVKS
N
I
V
K
I
G
V
C
F
A
V
L
AVPVSQTT
L
P
V
F
AAEQPGLKASQDNVNI
P
D
S
T
F
K
A
Y
L
N
G
L
LGQA-S-T-ANI-
T
E
A
QMD
S
L
T
Y
I
T
L
AN
I
N
VTDLTG
I
E
YAHNI
K
D
L
T
I
N
N
I
HATNYNQISGL
S
N
L
E
R
L
R
I
MG-ADVTSDKIPNLSG
L
T
N
L
T
---
L
L
DLSHSAHD
D
S
I
L
T
K
INTLPK
V
T
S
I
-
D
L
SYNG-AITDIMPLKTMPEL
K
S
L
N
I
Q
FDGVHDYRG
I
E
D
FP
K
L
N
T
L
-
L
A
Y
SQTIGG
K
K
L
--
I
N
SDIKSS
K
L
T
YNAEN
Q
T
L
Y
V
P
F
SLMTERTVNYDGY
V
P
D
F
V
K
STASSD
T
Y
F
T
M
N
E
Q
QVNG
N
R
L
T
I
TSDG
L
T
V
SDVSKTDFD
N
L
E
K
MEYN
A
R
I
D
L
S
YQSYN
T
P
E
Q
FQNGG
S
Y
T
I
S
M
P
I
Y
D
H
Y
F
T
V
D
H
S
L
N
I
TADSEK
T
Y
I
ENQLV
T
E
A
T
F
L
S
D
IHAKTDDGST
V
T
S
DFADKVDFNTP
G
T
Y
T
V
T
L
QSENNAG
L
K
AT
P
V
Q
V
N
V
T
I
K
A
K
T
T
I
TAD
E
K
I
T
Y
K
VDTSKT
E
A
A
F
L
A
D
I
K
ATTNDG
T
A
ITSD
F
A
T
V
V
DLSKPG
K
Y
V
V
T
LNAEN
D
L
Q
KAL
P
V
Q
V
M
V
I
V
EKETPIPDPTPTPTPDPTPTPDPSPTPNPVINPNVNKPEVPSYKIP
S
L
T
VNEKKAKAEP
S
K
EALPKTGDSLPV
A
G
A
T
V
G
F
L
L
I
G
L
S
W
F
VSRKK
40
Fugue
96.94
100%
-109
- C2 -
4L3A
2
?
A:
[48-516]
----------------------------------------
D
N
V
N
I
P
D
S
T
F
K
A
Y
L
N
G
L
L
G
Q
A
-
S
-
T
-
A
N
I
-
T
E
A
Q
M
D
S
L
T
Y
I
T
L
A
N
I
N
V
T
D
L
T
G
I
E
Y
A
H
N
I
K
D
L
T
I
N
N
I
H
A
T
N
Y
N
Q
I
S
G
L
S
N
L
E
R
L
R
I
M
G
-
A
D
V
T
S
D
K
I
P
N
L
S
G
L
T
N
L
T
---
L
L
D
L
S
H
S
A
H
D
D
S
I
L
T
K
I
N
T
L
P
K
V
T
S
I
-
D
L
S
Y
N
G
-
A
I
T
D
I
M
P
L
K
T
M
P
E
L
K
S
L
N
I
Q
F
D
G
V
H
D
Y
R
G
I
E
D
F
P
K
L
N
T
L
-
L
A
Y
S
Q
T
I
G
G
K
K
L
--
I
N
S
D
I
K
S
S
K
L
T
Y
N
A
E
N
Q
T
L
Y
V
P
F
S
L
M
T
E
R
T
V
N
Y
D
G
Y
V
P
D
F
V
K
S
T
A
S
S
D
T
Y
F
T
M
N
E
Q
Q
V
N
G
N
R
L
T
I
T
S
D
G
L
T
V
S
D
V
S
K
T
D
F
D
N
L
E
K
M
E
Y
N
A
R
I
D
L
S
Y
Q
S
Y
N
T
P
E
Q
F
Q
N
G
G
S
Y
T
I
S
M
P
I
Y
D
H
Y
F
T
V
D
H
S
L
N
I
T
A
D
S
E
K
T
Y
I
E
N
Q
L
V
T
E
A
T
F
L
S
D
I
H
A
K
T
D
D
G
S
T
V
T
S
D
F
A
D
K
V
D
F
N
T
P
G
T
Y
T
V
T
L
Q
S
E
N
N
A
G
L
K
A
T
P
V
Q
V
N
V
T
I
K
A
K
T
T
I
T
A
D
E
K
I
T
Y
K
V
D
T
S
K
T
E
A
A
F
L
A
D
I
K
A
T
T
N
D
G
T
A
I
T
S
D
F
A
T
V
V
D
L
S
K
P
G
K
Y
V
V
T
L
N
A
E
N
D
L
Q
K
A
L
P
V
Q
V
M
V
I
V
E
K
E
T
-----------------------------------------------------------------------------------------
1
PsiBlast_PDB
95.90
95%
-109
- C2 -
4L3A
2
?
A:
[48-516]
----------------------------------------
D
N
V
N
I
P
D
S
T
F
K
A
Y
L
N
G
L
L
G
Q
A
-
S
-
T
-
A
N
I
-
T
E
A
Q
M
D
S
L
T
Y
I
T
L
A
N
I
N
V
T
D
L
T
G
I
E
Y
A
H
N
I
K
D
L
T
I
N
N
I
H
A
T
N
Y
N
Q
I
S
G
L
S
N
L
E
R
L
R
I
M
G
-
A
D
V
T
S
D
K
I
P
N
L
S
G
L
T
N
L
T
---
L
L
D
L
S
H
S
A
H
D
D
S
I
L
T
K
I
N
T
L
P
K
V
T
S
I
-
D
L
S
Y
N
G
-
A
I
T
D
I
M
P
L
K
T
M
P
E
L
K
S
L
N
I
Q
F
D
G
V
H
D
Y
R
G
I
E
D
F
P
K
L
N
T
L
-
L
A
Y
S
Q
T
I
G
G
K
K
L
--
I
N
S
D
I
K
S
S
K
L
T
Y
N
A
E
N
Q
T
L
Y
V
P
F
S
L
M
T
E
R
T
V
N
Y
D
G
Y
V
P
D
F
V
K
S
T
A
S
S
D
T
Y
F
T
M
N
E
Q
Q
V
N
G
N
R
L
T
I
T
S
D
G
L
T
V
S
D
V
S
K
T
D
F
D
N
L
E
K
M
E
Y
N
A
R
I
D
L
S
Y
Q
S
Y
N
T
P
E
Q
F
Q
N
G
G
S
Y
T
I
S
M
P
I
Y
D
H
Y
F
T
V
D
H
S
L
N
I
T
A
D
S
E
K
T
Y
I
E
N
Q
L
V
T
E
A
T
F
L
S
D
I
H
A
K
T
D
D
G
S
T
V
T
S
D
F
A
D
K
V
D
F
N
T
P
G
T
Y
T
V
T
L
Q
S
E
N
N
A
G
L
K
A
T
P
V
Q
V
N
V
T
I
K
A
K
T
T
I
T
A
D
E
K
I
T
Y
K
V
D
T
S
K
T
E
A
A
F
L
A
D
I
K
A
T
T
N
D
G
T
A
I
T
S
D
F
A
T
V
V
D
L
S
K
P
G
K
Y
V
V
T
L
N
A
E
N
D
L
Q
K
A
L
P
V
Q
V
M
V
I
V
E
K
E
T
-----------------------------------------------------------------------------------------
21
PsiBlast_CBE
88.16
95%
-103
- C2 -
4L3A
3
?
B:
[46-440]
--------------------------------------
S
Q
D
N
V
N
I
P
D
S
T
F
K
A
Y
L
N
G
L
L
G
Q
A
-
S
-
T
-
A
N
I
-
T
E
A
Q
M
D
S
L
T
Y
I
T
L
A
N
I
N
V
T
D
L
T
G
I
E
Y
A
H
N
I
K
D
L
T
I
N
N
I
H
A
T
N
Y
N
Q
I
S
G
L
S
N
L
E
R
L
R
I
M
G
-
A
D
V
T
S
D
K
I
P
N
L
S
G
L
T
N
L
T
---
L
L
D
L
S
H
S
A
H
D
D
S
I
L
T
K
I
N
T
L
P
K
V
T
S
I
-
D
L
S
Y
N
G
-
A
I
T
D
I
M
P
L
K
T
M
P
E
L
K
S
L
N
I
Q
F
D
G
V
H
D
Y
R
G
I
E
D
F
P
K
L
N
T
L
-
L
A
Y
S
Q
T
I
G
G
K
K
L
--
I
N
S
D
I
K
S
S
K
L
T
Y
N
A
E
N
Q
T
L
Y
V
P
F
S
L
M
T
E
R
T
V
N
Y
D
G
Y
V
P
D
F
V
K
S
T
A
S
S
D
T
Y
F
T
M
N
E
Q
Q
V
N
G
N
R
L
T
I
T
S
D
G
L
T
V
S
D
V
S
K
T
D
F
D
N
L
E
K
M
E
Y
N
A
R
I
D
L
S
Y
Q
S
Y
N
T
P
E
Q
F
Q
N
G
G
S
Y
T
I
S
M
P
I
Y
D
H
Y
F
T
V
D
H
S
L
N
I
T
A
D
S
E
K
T
Y
I
E
N
Q
L
V
T
E
A
T
F
L
S
D
I
H
A
K
T
D
D
G
S
T
V
T
S
D
F
A
D
K
V
D
F
N
T
P
G
T
Y
T
V
T
L
Q
S
E
N
N
A
G
L
K
A
T
P
V
Q
V
N
V
T
I
K
A
K
T
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
81.39
99%
-113
- C2 -
4L3F
1
?
B:
[26-336]
----------------------------------------
D
N
V
N
I
P
D
S
T
F
K
A
Y
L
N
G
L
L
G
Q
A
-
S
-
T
-
A
N
I
-
T
E
A
Q
M
D
S
L
T
Y
I
T
L
A
N
I
N
V
T
D
L
T
G
I
E
Y
A
H
N
I
K
D
L
T
I
N
N
I
H
A
T
N
Y
N
Q
I
S
G
L
S
N
L
E
R
L
R
I
M
G
-
A
D
V
T
S
D
K
I
P
N
L
S
G
L
T
N
L
T
---
L
L
D
L
S
H
S
A
H
D
D
S
I
L
T
K
I
N
T
L
P
K
V
T
S
I
-
D
L
S
Y
N
G
-
A
I
T
D
I
M
P
L
K
T
M
P
E
L
K
S
L
N
I
Q
F
D
G
V
H
D
Y
R
G
I
E
D
F
P
K
L
N
T
L
-
L
A
Y
S
Q
T
I
G
G
K
K
L
--
I
N
S
D
I
K
S
S
K
L
T
Y
N
A
E
N
Q
T
L
Y
V
P
F
S
L
M
T
E
R
T
V
N
Y
D
G
Y
V
P
D
F
V
K
S
T
A
S
S
D
T
Y
F
T
M
N
E
Q
Q
V
N
G
N
R
L
T
I
T
S
D
G
L
T
V
S
D
V
S
K
T
D
F
D
N
L
E
K
M
E
Y
N
A
R
I
D
L
S
Y
Q
S
Y
N
T
P
E
Q
F
Q
N
G
G
S
Y
T
I
S
M
P
I
Y
D
H
Y
F
T
V
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
79.70
99%
-111
- C2 -
4L3F
1
?
F:
[26-336]
----------------------------------------
D
N
V
N
I
P
D
S
T
F
K
A
Y
L
N
G
L
L
G
Q
A
-
S
-
T
-
A
N
I
-
T
E
A
Q
M
D
S
L
T
Y
I
T
L
A
N
I
N
V
T
D
L
T
G
I
E
Y
A
H
N
I
K
D
L
T
I
N
N
I
H
A
T
N
Y
N
Q
I
S
G
L
S
N
L
E
R
L
R
I
M
G
-
A
D
V
T
S
D
K
I
P
N
L
S
G
L
T
N
L
T
---
L
L
D
L
S
H
S
A
H
D
D
S
I
L
T
K
I
N
T
L
P
K
V
T
S
I
-
D
L
S
Y
N
G
-
A
I
T
D
I
M
P
L
K
T
M
P
E
L
K
S
L
N
I
Q
F
D
G
V
H
D
Y
R
G
I
E
D
F
P
K
L
N
T
L
-
L
A
Y
S
Q
T
I
G
G
K
K
L
--
I
N
S
D
I
K
S
S
K
L
T
Y
N
A
E
N
Q
T
L
Y
V
P
F
S
L
M
T
E
R
T
V
N
Y
D
G
Y
V
P
D
F
V
K
S
T
A
S
S
D
T
Y
F
T
M
N
E
Q
Q
V
N
G
N
R
L
T
I
T
S
D
G
L
T
V
S
D
V
S
K
T
D
F
D
N
L
E
K
M
E
Y
N
A
R
I
D
L
S
Y
Q
S
Y
N
T
P
E
Q
F
Q
N
G
G
S
Y
T
I
S
M
P
I
Y
D
H
Y
F
T
V
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
79.55
99%
-116
- C2 -
4L3F
1
?
H:
[26-336]
----------------------------------------
D
N
V
N
I
P
D
S
T
F
K
A
Y
L
N
G
L
L
G
Q
A
-
S
-
T
-
A
N
I
-
T
E
A
Q
M
D
S
L
T
Y
I
T
L
A
N
I
N
V
T
D
L
T
G
I
E
Y
A
H
N
I
K
D
L
T
I
N
N
I
H
A
T
N
Y
N
Q
I
S
G
L
S
N
L
E
R
L
R
I
M
G
-
A
D
V
T
S
D
K
I
P
N
L
S
G
L
T
N
L
T
---
L
L
D
L
S
H
S
A
H
D
D
S
I
L
T
K
I
N
T
L
P
K
V
T
S
I
-
D
L
S
Y
N
G
-
A
I
T
D
I
M
P
L
K
T
M
P
E
L
K
S
L
N
I
Q
F
D
G
V
H
D
Y
R
G
I
E
D
F
P
K
L
N
T
L
-
L
A
Y
S
Q
T
I
G
G
K
K
L
--
I
N
S
D
I
K
S
S
K
L
T
Y
N
A
E
N
Q
T
L
Y
V
P
F
S
L
M
T
E
R
T
V
N
Y
D
G
Y
V
P
D
F
V
K
S
T
A
S
S
D
T
Y
F
T
M
N
E
Q
Q
V
N
G
N
R
L
T
I
T
S
D
G
L
T
V
S
D
V
S
K
T
D
F
D
N
L
E
K
M
E
Y
N
A
R
I
D
L
S
Y
Q
S
Y
N
T
P
E
Q
F
Q
N
G
G
S
Y
T
I
S
M
P
I
Y
D
H
Y
F
T
V
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
79.00
99%
-111
- C2 -
4L3F
-
?
A:
[26-336]
----------------------------------------
D
N
V
N
I
P
D
S
T
F
K
A
Y
L
N
G
L
L
G
Q
A
-
S
-
T
-
A
N
I
-
T
E
A
Q
M
D
S
L
T
Y
I
T
L
A
N
I
N
V
T
D
L
T
G
I
E
Y
A
H
N
I
K
D
L
T
I
N
N
I
H
A
T
N
Y
N
Q
I
S
G
L
S
N
L
E
R
L
R
I
M
G
-
A
D
V
T
S
D
K
I
P
N
L
S
G
L
T
N
L
T
---
L
L
D
L
S
H
S
A
H
D
D
S
I
L
T
K
I
N
T
L
P
K
V
T
S
I
-
D
L
S
Y
N
G
-
A
I
T
D
I
M
P
L
K
T
M
P
E
L
K
S
L
N
I
Q
F
D
G
V
H
D
Y
R
G
I
E
D
F
P
K
L
N
T
L
-
L
A
Y
S
Q
T
I
G
G
K
K
L
--
I
N
S
D
I
K
S
S
K
L
T
Y
N
A
E
N
Q
T
L
Y
V
P
F
S
L
M
T
E
R
T
V
N
Y
D
G
Y
V
P
D
F
V
K
S
T
A
S
S
D
T
Y
F
T
M
N
E
Q
Q
V
N
G
N
R
L
T
I
T
S
D
G
L
T
V
S
D
V
S
K
T
D
F
D
N
L
E
K
M
E
Y
N
A
R
I
D
L
S
Y
Q
S
Y
N
T
P
E
Q
F
Q
N
G
G
S
Y
T
I
S
M
P
I
Y
D
H
Y
F
T
V
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
60.96
92%
-119
- C2 -
4EZG
1
?
A:
[7-191]
----------------------------------
G
L
K
A
S
Q
D
N
V
N
I
P
D
S
T
F
K
A
Y
L
N
G
L
L
G
Q
S
-
S
-
T
-
A
N
I
-
T
E
A
Q
M
N
S
L
T
Y
I
T
L
A
N
I
N
V
T
D
L
T
G
I
E
Y
A
H
N
I
K
D
L
T
I
N
N
I
H
A
T
N
Y
N
P
I
S
G
L
S
N
L
E
R
L
R
I
M
G
-
K
D
V
T
S
D
K
I
P
N
L
S
G
L
T
S
L
T
---
L
L
D
I
S
H
S
A
H
D
D
S
I
L
T
K
I
N
T
L
P
K
V
N
S
I
-
D
L
S
Y
N
G
-
A
I
T
D
I
M
P
L
K
T
L
P
E
L
K
S
L
N
I
Q
F
D
G
V
H
D
Y
R
G
I
E
D
F
P
K
L
N
Q
L
-
Y
A
F
S
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53
HHSearch
53.45
24%
-101
- C2 -
1M9S
5
INLB_LISMO
A:
[13-276]
------------------------------------------
Q
I
F
P
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
-
S
V
T
-
D
A
V
-
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
T
N
L
K
N
L
G
W
L
F
L
D
E
-
N
K
I
K
D
L
S
S
--
L
K
D
L
K
K
L
K
---
S
L
S
L
E
H
N
G
I
--
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
-
Y
L
G
N
N
--
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
-
Y
L
S
K
N
H
I
S
D
L
R
A
LA
G
L
K
N
L
D
V
L
E
L
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
HHSearch
51.63
25%
-114
- C2 -
1H6T
-
INLB_LISMO
A:
[45-224]
-----------------------------------------
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
-
T
-
D
A
V
-
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
-
N
K
V
K
D
L
S
S
--
L
K
D
L
K
K
L
K
---
S
L
S
L
E
H
N
G
I
--
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
-
Y
L
G
N
N
--
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
-
Y
L
S
K
N
H
I
S
D
L
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
61
HHSearch
51.05
16%
-99
- C2 -
1XEU
-
?
A:
[46-222]
-------------------------------------------
V
F
P
D
P
G
L
A
N
A
V
K
Q
N
L
G
K
Q
-
S
-
V
T
D
L
V
-
S
Q
K
E
L
S
G
V
Q
N
F
N
G
D
N
S
N
I
Q
S
L
A
G
M
Q
F
F
T
N
L
K
E
L
H
L
S
H
N
Q
I
S
D
L
S
P
L
K
D
L
T
K
L
E
E
L
S
V
N
R
-
N
R
L
K
N
L
N
G
I
---
P
S
A
C
L
S
---
R
L
F
L
D
N
N
E
L
R
--
D
T
D
S
L
I
H
L
K
N
L
E
I
L
-
S
I
R
N
N
--
K
L
K
S
I
V
M
L
G
F
L
S
K
L
E
V
L
D
L
H
G
N
E
I
T
N
T
G
G
L
T
R
L
K
K
V
N
W
I
-
D
L
T
G
Q
K
C
V
N
E
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
50.68
27%
-111
- C2 -
2OMX
-
INLA_LISMO
A:
[62-207]
--------------------------------------------------------------------------
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
D
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
D
I
T
P
L
A
N
L
T
N
L
T
G
L
T
L
F
N
-
N
Q
I
T
--
D
I
D
P
L
K
N
L
T
N
L
N
---
R
L
E
L
S
S
N
T
I
S
D
--
I
S
A
L
S
G
L
T
S
L
Q
Q
L
-
N
F
S
S
N
--
Q
V
T
D
L
K
P
L
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
S
V
L
A
K
L
T
N
L
E
S
L
-
I
A
T
N
N
Q
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
59
HHSearch
50.62
20%
-90
- C2 -
1H6U
-
?
A:
[95-262]
------------------------------------------------------------------------
Q
Y
L
N
N
L
I
G
L
E
L
K
D
N
Q
I
T
D
L
A
P
L
K
N
L
T
K
I
T
E
L
E
L
S
G
N
P
L
K
N
V
S
A
I
A
G
L
Q
S
I
K
T
L
D
L
T
S
-
T
Q
I
T
D
V
T
P
--
L
A
G
L
S
N
L
Q
---
V
L
Y
L
D
L
N
Q
I
--
T
N
I
S
P
L
A
G
L
T
N
L
Q
Y
L
-
S
I
G
N
A
--
Q
V
S
D
L
T
P
L
A
N
L
S
K
L
T
T
L
K
A
D
D
N
K
I
S
D
I
S
P
L
A
S
L
P
N
L
I
E
V
-
H
L
K
N
N
Q
I
S
D
V
S
P
LA
N
T
S
N
L
F
I
V
T
L
T
N
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
49.44
28%
-123
- C2 -
2OMU
-
INLA_LISMO
A:
[62-207]
--------------------------------------------------------------------------
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
D
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
D
I
T
P
L
A
N
L
T
N
L
T
G
L
T
L
F
N
-
N
Q
I
T
--
D
I
D
P
L
K
N
L
T
N
L
N
---
R
L
E
L
S
S
N
T
I
S
D
-----
I
S
A
L
S
G
L
T
S
L
Q
Q
L
S
F
S
S
N
Q
V
T
D
L
K
P
L
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
S
V
L
A
K
L
T
N
L
E
S
L
-
I
A
T
N
N
Q
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
49.14
28%
-121
- C2 -
2OMZ
-
INLA_LISMO
A:
[97-241]
--------------------------------------------------------------------------
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
D
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
D
I
T
P
L
A
N
L
T
N
L
T
G
L
T
L
F
N
-
N
Q
I
T
--
D
I
D
P
L
K
N
L
T
N
L
N
---
R
L
E
L
S
S
N
T
I
S
D
-----
I
S
A
L
S
G
L
T
S
L
Q
Q
L
S
F
G
N
-
Q
V
T
D
L
K
P
L
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
S
V
L
A
K
L
T
N
L
E
S
L
-
I
A
T
N
N
Q
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
48.81
30%
-106
- C2 -
4R58
-
?
A:
[14-178]
---------------------------------------------
P
D
D
A
F
A
E
T
I
K
A
N
L
K
K
K
-
S
V
T
-
D
A
V
-
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
L
K
T
L
K
L
S
N
------
N
K
I
T
D
I
S
A
L
K
Q
L
N
N
L
G
W
L
D
L
S
N
N
G
I
T
D
I
S
A
L
K
N
L
A
SLH
T
L
D
L
S
N
N
G
I
T
D
--
I
S
A
L
K
N
L
D
N
L
H
T
L
-
D
L
S
N
N
G
--
I
T
D
I
S
A
L
K
N
L
D
N
L
H
T
L
D
L
S
N
N
G
I
T
D
I
S
A
L
K
N
L
T
S
L
H
T
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
48.57
29%
-111
- C2 -
4FMZ
3
?
A:
[17-188]
---------------------------------------------
P
D
A
D
L
A
E
G
I
R
A
V
L
Q
K
A
-
S
-
V
-
T
D
V
V
T
Q
E
E
L
E
S
I
T
K
L
V
V
A
G
E
K
V
A
S
I
Q
G
I
E
Y
L
T
N
L
E
Y
L
N
L
N
G
N
Q
I
T
D
---
I
S
P
L
S
N
L
V
K
L
T
N
L
Y
---
I
G
T
N
K
I
T
D
I
S
A
L
Q
N
L
T
N--
L
R
E
L
Y
L
N
E
D
N
I
S
D
I
S
P
L
A
N
L
T
K
M
Y
S
L
-
N
L
G
A
N
H
-
N
L
S
D
L
S
P
L
S
N
M
T
G
L
N
Y
L
T
V
T
E
S
K
V
K
D
V
T
P
I
A
N
L
T
D
L
Y
S
L
S
L
N
Y
N
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
48.27
28%
-122
- C2 -
1O6V
-
INLA_LISMO
A:
[67-211]
--------------------------------------------------------------------------
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
D
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
D
I
T
P
L
A
N
L
T
N
L
T
G
L
T
L
F
N
-
N
Q
I
T
--
D
I
D
P
L
K
N
L
T
N
L
N
---
R
L
E
L
S
S
N
T
I
S
D
-----
I
S
A
L
S
G
L
T
S
L
Q
Q
L
S
F
G
N
-
Q
V
T
D
L
K
P
L
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
S
V
L
A
K
L
T
N
L
E
S
L
-
I
A
T
N
N
Q
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
47.71
28%
-122
- C2 -
2OMV
1
INLA_LISMO
A:
[62-206]
--------------------------------------------------------------------------
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
D
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
D
I
T
P
L
A
N
L
T
N
L
T
G
L
T
L
F
N
-
N
Q
I
T
--
D
I
D
P
L
K
N
L
T
N
L
N
---
R
L
E
L
S
S
N
T
I
S
D
-----
I
S
A
L
S
G
L
T
S
L
Q
Q
L
N
F
G
N
-
Q
V
T
D
L
K
P
L
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
S
V
L
A
K
L
T
N
L
E
S
L
-
I
A
T
N
N
Q
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
47.65
28%
-125
- C2 -
1O6S
-
INLA_LISMO
A:
[67-211]
--------------------------------------------------------------------------
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
D
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
D
I
T
P
L
A
N
L
T
N
L
T
G
L
T
L
F
N
-
N
Q
I
T
--
D
I
D
P
L
K
N
L
T
N
L
N
---
R
L
E
L
S
S
N
T
I
S
D
-----
I
S
A
L
S
G
L
T
S
L
Q
Q
L
S
F
G
N
-
Q
V
T
D
L
K
P
L
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
S
V
L
A
K
L
T
N
L
E
S
L
-
I
A
T
N
N
Q
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------