@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1389: (2016-03-24 )
VDFVIEMLGIRKEFSGFVANDNITLQLKQGEIHALLGENGAGKSTLMNVLFGLYEPDGGEIRVRGTKENINSPNKANELGIGMVHQHFMLVDKFTVAENIILGKEPSKLGVIEKKKAIEEIKEISDRYGLRVDPNAIVRDISIGMQQRVEILKTLYRGADILIFDEPTAVLTPQEIKELIQIMRSLIKEGKSIILITHKLKEIMDVCDRVTVIRRGKGMGTVNVPETTPQDLANLMVGREVVFTTEKIDANPGKDVLEVKDLVVKESRGVESVRGLNLTVRAGEIVGIAGVDGNGQSELISAIAGLSKVTSGSILLNGEHIENKKPRKITEAGLGHIPEDRHKHGLVLEMSLGENIALQTYYKKPISSKGFLNHKAMYDFARELIEEYDVRASSEYVAAKSLSGGNQQKAIIAREIHRNPDFLIAAQPTRGLDVGAIEFIHRRLIEQRDNGKAVLLMSFELDEIMNVSDRIAVIYEGKIVAIVDPKETTEQELGLMMAGSSKQEAEMGEKEHV
Atome Classification :
(36 SA)
.........10....-.-------...20.....-...30........40........50.......--.60.--.--.-------..--...70.--.----.--.....--80........-90........100.....------..-110.......120.......130-.......140--.........150.......160.......170.......180......-.-190.......200.......210.......220.-.....-..-230---.-....---.------.240-----.......-----.--250.-----......260......-.270.......280.......290.......300.......310.......320....---....-------330.......340.------------------------------------------.--.....350.......360..---.....370------------------------........380.......390..-.....400.......410.......420.......430.......440......-.450.......460.......470.......480.......490.......500.......510.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
VD
F
V
I
E
M
LG
I
R
K
E
FS-
G
-------
F
VAND
N
I
T
L
Q
-
L
KQG
E
I
H
A
L
LGENGA
G
K
S
T
L
M
N
V
L
F
G
LYEPDG--
G
E
I
R
--
V
--
R
-------GT--KENINS--P----N--K
A
N
E
L
--
G
I
G
M
V
H
Q
H
F
M
-
L
V
D
K
F
T
VAE
N
I
ILGKEPS------KL-G
V
I
E
K
K
K
A
I
E
E
I
K
E
I
S
D
RYGLRV-D
P
N
A
I
V
R
D
----
I
S
I
G
M
Q
Q
R
V
E
I
L
K
T
L
YRGA
D
I
L
I
FDEPTAVL
T
P
Q
E
I
K
E
L
I
Q
I
M
R
S
L
I
K-E-G
K
S
I
I
L
I
T
H
K
L
K
E
I
M
D
V
C
D
R
V
T
V
I
RRGKGMGT-V-NVPET-
T
P
-
Q
D
L
---
A
-
N
L
M
V---G------
R
E
V
------
V
F
T
TEKI-----D--ANPG-----K
D
V
L
E
V
K
D
L
V
V
KESR-GVESVRG
L
N
L
T
V
RA
G
E
I
V
G
I
AGVDGN
G
Q
S
E
L
I
S
A
I
A
G
L
S
KVTS
G
S
I
L
L
NGEHI-ENKK---PR
K
I
-------
T
E
AGLGHIPEDRHK------------------------------------------H--
G
L
V
L
E
MSLGE
N
I
A
L
Q
T
YYKK---PISSKGF-------------------------L
N
H
K
A
M
Y
D
F
A
R
E
L
I
E
E
YDVRASS-
E
Y
V
A
A
KSLSGGN
Q
Q
K
A
I
I
A
R
E
IHRNP
D
F
L
I
AAQPTRGL
D
V
G
A
I
E
F
I
H
R
R
L
I
E
QR-DNG
K
A
V
L
L
M
S
F
E
L
D
E
I
MNVS
D
R
I
A
V
I
YE
G
K
I
V
A
I
VDPKET
T
E
Q
E
L
G
L
M
MAGSS
K
Q
E
A
EMGEKEHV
92
HHSearch
70.12
18%
-79
- C- -
2IW3
7
EF3A_YEAST
A:
[437-979]
-----
C
N
C
E
F
S
L
A
Y
G
-
A
-------
K
I
L
L
N
K
T
Q
L
R
-
L
K
R
A
R
R
Y
G
I
C
G
P
N
G
C
G
K
S
T
L
M
R
A
I
A
N
--------
G
Q
V
------
D
-------
G
F
--
P
T
Q
---------------
E
E
C
--
R
T
V
Y
V
E
H
D
I
D
G
T
H
S
D
T
S
V
L
D
F
V
F
E
S
G
V
G
-----------------
T
K
E
A
I
K
D
K
L
I
E
F
G
F
T
D
E
M
I
A
M
P
I
S
A
----
L
S
G
G
W
K
M
K
L
A
L
A
R
A
V
L
R
N
A
D
I
L
L
L
D
E
P
T
N
H
L
D
T
V
N
V
A
W
L
V
N
Y
L
N
T
C
-----
G
I
T
S
I
T
I
S
H
D
S
V
F
L
D
N
V
C
E
Y
I
I
N
Y
E
G
L
K
L
R
K
Y
K
G
-
N
F
T
E
F
-
V
K
-
K
C
P
---
A
A
K
A
Y
E
ELS
N
------
T
D
L
------
E
F
K
F
P
E
P
GYLEG
V
--
K
T
K
Q
-----
K
A
I
V
K
V
T
N
M
E
F
Q
Y
P
G
T
S
K
P
Q
I
T
D
I
N
F
Q
C
S
L
S
S
R
I
A
V
I
G
P
N
G
A
G
K
S
T
L
I
N
V
L
T
G
E
L
L
P
T
S
G
E
V
Y
T
H
E
N
C
R
I
A
Y
I
K
Q
H
A
F
A
H
I
ESHLDKT
P
S
E
Y
I
Q
W
R
F
Q
T
G
E
D
RETMDRANRQINEND
A
E
A
M
N
K
I
F
K
I
EG
T
P
R
R
IAGIH
S
R
R
K
F
K
N
T
Y
E
Y
E
C
S
F
L
L
G
E
N
I
G
M
K
S
E
R
W
V
P
M
M
S
V
D
N
A
W
I
P
RGELVESH
S
K
M
V
A
E
V
D
M
K
E
A
L
A
S
G
Q
F
R
P
L
T
R
K
E
I
E
E
H
C
S
M
L
G
L
D
P
E
I
V
S
H
S
R
I
R
G
L
S
G
G
Q
K
V
K
L
V
L
A
A
G
T
W
Q
R
P
H
L
I
V
L
D
E
P
T
N
Y
L
D
R
D
S
L
G
A
L
S
K
A
L
K
E
F
----
E
G
G
V
I
I
I
T
H
S
A
E
F
T
K
N
L
T
E
E
V
W
A
V
K
D
G
R
M
T
P
S
-------------------------------
94
HHSearch
67.11
19%
-58
- C1 -
3OZX
5
?
A:
[4-465]
--------
E
V
I
H
R
Y
K
V
N
-------
G
F
K
L
F
G
L
P
T
--
P
K
N
N
T
I
L
G
V
L
G
K
N
G
V
G
K
T
T
V
L
K
I
L
A
G
E
I
I
P
N
F
--
G
D
P
N
--
S
--
K
-------
V
G
--
K
D
E
V
L
--------
K
--
R
F
R
G
K
--
E
I
Y
N
Y
F
K
E
L
Y
-
S
N
-
E
L
K
I
V
H
K
I
Q
Y
V
E
Y
A
S
KFLKGT
V
N
-
E
I
L
T
K
I
D
E
R
G
K
K
D
E
V
K
E
L
L
N
M
T
N
-
L
W
N
K
D
A
N
I
----
L
S
G
G
G
L
Q
R
L
L
V
A
A
S
L
L
R
E
A
D
V
Y
I
F
D
Q
P
S
S
Y
L
D
V
R
E
R
M
N
M
A
K
A
I
R
E
L
L
K
---
N
K
Y
V
I
V
V
D
H
D
L
I
V
L
D
Y
L
T
D
L
I
H
I
I
Y
G
-
E
S
S
V
Y
-
G
-
R
V
S
K
S
Y
A
A
-
R
V
G
---
I
-
N
N
F
L
K
--
G
------
Y
L
P
------
A
E
N
M
K
I
R
-----
P
--
D
E
I
K
FMLKL
K
T
K
M
K
W
T
K
I
I
K
K
L
G
---
D
F
Q
L
V
V
D
N
G
E
A
K
E
G
E
I
I
G
I
L
G
P
N
G
I
G
K
T
T
F
A
R
I
L
V
G
E
I
T
A
D
E
G
S
V
T
P
E
K
Q
I
------------------------
L
S
Y
K
P
Q
R
I
-----------------------------------------------
F
P
N
Y
D
G
T
V
Q
Q
Y
L
E
N
A
S
K
D
A
L
--------------------------------------
S
T
S
S
W
F
F
E
E
V
T
K
R
L
N
L
H
R
-
L
-
L
E
S
N
V
N
D
L
S
G
G
E
L
Q
K
L
Y
I
A
A
T
L
A
K
E
A
D
L
Y
V
L
D
Q
P
S
S
Y
L
D
V
E
E
R
Y
I
V
A
K
A
I
K
R
V
T
R
E
R
K
A
V
T
F
I
I
D
H
D
L
S
I
H
D
Y
I
A
D
R
I
I
V
F
K
G
E
P
E
K
---------------------------------
110
HHSearch
67.00
29%
-84
* C2 *
3TUI
1
METN_ECOLI
C:
[23-252]
--
H
M
I
K
L
S
N
I
T
K
V
F
H
-
Q
GTRT---
I
Q
A
L
N
N
V
S
L
H
-
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
--
G
S
V
L
--
V
--
D
-------
G
Q
--
E
L
T
T
L
S
--
E
----
S
EL
T
K
A
R
R
--
Q
I
G
M
I
F
Q
H
F
N
-
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
E
L
D
------
N
----
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
-
K
H
D
S
Y
P
S
N
----
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
-
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
-
D
-
T
V
S
E
V
-
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
65.77
29%
-86
- C2 -
3TUI
1
METN_ECOLI
C:
[43-241]
--------------------------
A
L
N
N
V
S
L
H
-
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
--
G
S
V
L
--
V
--
D
-------
G
Q
--
E
L
T
T
L
S
--
E
----
S
--
E
L
T
K
A
RR
Q
I
G
M
I
F
Q
H
F
N
-
L
L
S
S
R
T
V
F
G
N
V
A
L
---
P
L
------
E
L
-
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
-
K
H
D
S
Y
P
S
N
----
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
-
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
64.94
29%
-87
- C2 -
3TUZ
1
METN_ECOLI
C:
[43-241]
--------------------------
A
L
N
N
V
S
L
H
-
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
--
G
S
V
L
--
V
--
D
-------
G
Q
--
E
L
T
T
L
S
--
E
----
S
--
E
L
T
K
A
RR
Q
I
G
M
I
F
Q
H
F
N
-
L
L
S
S
R
T
V
F
G
N
V
A
L
---
P
L
------
E
L
-
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
-
K
H
D
S
Y
P
S
N
----
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
-
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
64.45
32%
-89
- C2 -
2OUK
1
?
C:
[24-246]
---
M
I
D
V
H
Q
L
K
K
S
F
G
-
S
-------
L
E
V
L
K
G
I
N
V
H
-
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
--
G
E
I
I
--
I
--
D
-------
G
I
NL
K
A
K
D
T
N
--
L
----
N
--
K
V
R
E
---
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
--
P
M
------
K
V
-
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
----
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
-----
G
G
-
Y
-
I
I
E
E
G
-
K
P
-
E
D
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
84
Fugue
64.17
21%
-82
- C2 -
1OXS
23
?
C:
[1-352]
-
M
V
R
I
I
V
K
N
V
S
K
V
F
K
-
K
GK-----
V
V
A
L
D
N
V
N
I
N
-
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
--
G
E
L
Y
--
F
DD
R
-------
L
V
--
A
S
N
G
K
L
--
I
----
V
--
P
P
E
D
R
--
K
I
G
M
V
F
Q
T
W
A
-
L
Y
P
N
L
T
A
F
E
N
I
A
F
P
L
T
N
M
------
K
M
----
S
K
E
E
I
R
K
R
V
E
E
V
A
K
I
L
D
I
H
H
-
V
L
N
H
F
P
R
E
----
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
-
R
L
G
V
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
K
G
-
K
L
V
Q
-
V
-
G
K
P
E
D
-
L
Y
-
D
N
P
---
V
-
S
I
Q
V
---
A
------
S
L
I
-------
G
E
I
N
E
L
-----
E
--
G
K
V
T
-----
N
E
G
V
V
I
G
S
L
R
F
P
V
S
V
----
S
S
D
R
A
I
I
G
I
R
P
E
D
-----------------------------
V
K
L
S
K
D
V
I
-
K
D
D
S
---
W
I
L
V
-------
G
K
G
K
V
K
V
I
G
Y
Q
G
G
L
------------------------------------------
F
--
R
I
T
I
T
P
L
------------------------------------------------------------------------------------------------
D
S
E
E
E
I
F
T
Y
S
D
H
P
I
H
S
G
----------------------------------
E
E
V
L
V
Y
V
R
K
D
K
I
K
V
F
E
K
----------------------------
90
HHSearch
63.22
22%
-69
- C1 -
3BK7
4
?
A:
[83-547]
---
A
I
S
I
V
N
L
P
E
Q
L
D
-
E
D
CVHRYG
V
N
A
F
V
L
Y
R
L
P
I
V
K
D
G
M
V
V
G
I
V
G
P
N
G
T
G
K
T
T
A
V
K
I
L
A
G
Q
L
I
P
N
L
--
C
E
D
N
DS
W
--
D
N
V
I
R
A
F
R
G
N
--
E
L
Q
N
Y
F
--
E
R
---
L
--
K
N
G
E
I
--
R
P
V
V
K
P
Q
Y
V
D
-
L
L
P
K
-
A
V
K
G
K
V
R
E
L
---------------
L
K
K
V
D
E
V
G
K
F
E
E
V
V
K
E
L
E
L
E
N
-
V
L
D
R
E
L
H
Q
----
L
S
G
G
E
L
Q
R
V
A
I
A
A
A
L
L
R
K
A
H
F
Y
F
F
D
E
P
S
S
Y
L
D
I
R
Q
R
L
K
V
A
R
V
I
R
R
L
A
N
-
E
-
G
K
A
V
L
V
V
E
H
D
L
A
V
L
D
Y
L
S
D
V
I
H
V
V
Y
G
E
P
G
V
Y
G
-
I
-
F
S
K
P
K
-
G
T
R
N
G
I
N
E
F
L
-
Q
G
Y
L
---
K
DENVRF
R
P
Y
------
E
I
R
F
T
K
L
SER--
V
--
D
V
E
R
-----
E
T
L
V
E
Y
P
R
L
V
K
D
Y
G
---
S
F
K
L
E
V
E
P
G
E
I
R
K
G
E
V
I
G
I
V
G
P
N
G
I
G
K
T
T
F
V
K
M
L
A
G
V
E
E
P
T
E
G
K
V
E
W
D
L
T
-------------------------
V
A
Y
K
P
Q
Y
I
K
-----------------------------------------------
A
E
Y
E
G
T
V
Y
E
L
L
S
K
I
D
S
S
K
----------
L
--------------------------
N
---
S
N
F
Y
K
T
E
L
L
K
P
L
G
I
I
D
-
L
-
Y
D
R
N
V
E
D
L
S
G
G
E
L
Q
R
V
A
I
A
A
T
L
L
R
D
A
D
I
Y
L
L
D
E
P
S
A
Y
L
D
V
E
Q
R
L
A
V
S
R
A
I
R
H
L
M
E
K
N
E
K
T
A
L
V
V
E
H
D
V
L
M
I
D
Y
V
S
D
R
L
I
V
F
E
G
-------------------------------------
5
PsiBlast_PDB
62.59
32%
-85
- C2 -
4YMW
-
?
J:
[7-223]
---------
V
Y
K
N
F
G
-
S
-------
L
E
V
L
K
G
V
T
L
K
-
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
--
G
E
V
F
--
I
--
D
-------
G
V
--
K
I
N
-
N
G
--
K
----
V
--
N
I
N
K
V
RQ
K
V
G
M
V
F
Q
H
F
N
-
L
F
P
H
L
T
A
I
E
N
I
T
L
A
--
P
V
------
K
V
-
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-
K
K
D
Q
Y
P
I
K
----
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
------
V
-
I
V
E
E
G
-
T
P
-
E
E
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
62.32
32%
-88
- C2 -
2OLJ
4
?
A:
[24-246]
---
M
I
D
V
H
Q
L
K
K
S
F
G
-
S
-------
L
E
V
L
K
G
I
N
V
H
-
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
--
G
E
I
I
--
I
--
D
-------
G
I
NL
K
A
K
D
T
N
--
L
----
N
--
K
V
R
E
---
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
--
P
M
------
K
V
-
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
----
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
-----
G
G
-
Y
-
I
I
E
E
G
-
K
P
-
E
D
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
93
HHSearch
61.62
22%
-55
- C1 -
1YQT
4
?
A:
[25-479]
-------
E
D
C
V
H
R
Y
G
-
V
N------
A
F
V
L
Y
R
L
P
-
V
-
V
K
E
G
M
V
V
G
I
V
G
P
N
G
T
G
K
S
T
A
V
K
I
L
A
G
Q
L
I
P
N
L
CG
D
N
D
S
--
W
--
D
-------
G
V
--
I
R
A
F
R
G
NE
L
Q
N
Y
F
E
--
K
L
K
N
G
E
I
R
P
V
V
K
P
Q
Y
V
D
-
L
I
P
K
A
V
K
G
K
V
I
E
L
-
L
---------------
K
K
A
D
E
T
G
K
L
E
E
V
V
K
A
L
E
L
E
N
-
V
L
E
R
E
I
Q
H
----
L
S
G
G
E
L
Q
R
V
A
I
A
A
A
L
L
R
N
A
T
F
Y
F
F
D
E
P
S
S
Y
L
D
I
R
Q
R
L
N
A
A
R
A
I
R
R
L
S
E
-
E
-
G
K
S
V
L
V
V
E
H
D
L
A
V
L
D
Y
L
S
D
I
I
H
V
V
Y
G
E
P
G
V
Y
G
-
I
F
S
Q
P
K
G
-
T
R
-
N
G
I
N
E
F
L
-
R
G
Y
L
---
K
------
D
E
N
VRFRP
Y
E
I
K
F
T
K
T
G----
E
RV
E
I
E
R
-----
E
T
L
V
T
Y
P
R
L
V
K
D
Y
G
---
S
F
R
L
E
V
E
P
G
E
I
K
K
G
E
V
I
G
I
V
G
P
N
G
I
G
K
T
T
F
V
K
M
L
A
G
V
E
E
P
T
E
G
K
I
E
W
D
L
T
-------------------------
V
A
Y
K
P
Q
Y
I
-----------------------------------------------
K
A
D
Y
E
G
T
V
Y
E
L
L
S
K
I
D
A
S
K
----------
L
-------------------------
N
----
S
N
F
Y
K
T
E
L
L
K
P
L
G
I
I
D
-
L
-
Y
D
R
E
V
N
E
L
S
G
G
E
L
Q
R
V
A
I
A
A
T
L
L
R
D
A
D
I
Y
L
L
D
E
P
S
A
Y
L
D
V
E
Q
R
L
A
V
S
R
A
I
R
H
L
M
E
K
N
E
K
T
A
L
V
V
E
H
D
V
L
M
I
D
Y
V
S
D
R
L
M
V
F
E
G
E
P
-----------------------------------
3
PsiBlast_PDB
61.34
32%
-86
- C2 -
4YMU
2
?
J:
[7-223]
---------
V
Y
K
N
F
G
-
S
-------
L
E
V
L
K
G
V
T
L
K
-
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
--
G
E
V
F
--
I
--
D
-------
G
V
--
K
I
N
-
N
G
--
K
----
V
--
N
I
N
K
V
RQ
K
V
G
M
V
F
Q
H
F
N
-
L
F
P
H
L
T
A
I
E
N
I
T
L
A
--
P
V
------
K
V
-
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-
K
K
D
Q
Y
P
I
K
----
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
------
V
-
I
V
E
E
G
-
T
P
-
E
E
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
61.16
32%
-88
- C2 -
4YMS
-
?
J:
[7-223]
---------
V
Y
K
N
F
G
-
S
-------
L
E
V
L
K
G
V
T
L
K
-
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
--
G
E
V
F
--
I
--
D
-------
G
V
--
K
I
N
-
N
G
--
K
----
V
--
N
I
N
K
V
RQ
K
V
G
M
V
F
Q
H
F
N
-
L
F
P
H
L
T
A
I
E
N
I
T
L
A
--
P
V
------
K
V
-
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-
K
K
D
Q
Y
P
I
K
----
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
------
V
-
I
V
E
E
G
-
T
P
-
E
E
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
61.13
32%
-85
- C2 -
4YMU
2
?
A:
[7-223]
---------
V
Y
K
N
F
G
-
S
-------
L
E
V
L
K
G
V
T
L
K
-
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
--
G
E
V
F
--
I
--
D
-------
G
V
--
K
I
N
-
N
G
--
K
----
V
--
N
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
-
L
F
P
H
L
T
A
I
E
N
I
T
L
A
--
P
V
------
K
V
-
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-
K
K
D
Q
Y
P
I
K
----
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
------
V
-
I
V
E
E
G
-
T
P
-
E
E
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
60.69
30%
-86
- C2 -
3DHW
-
METN_ECOLI
C:
[20-218]
--------------------------
A
L
N
N
V
S
L
H
-
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
--
G
S
V
L
--
V
--
D
-------
G
Q
--
E
L
T
T
L
S
--
E
----
S
--
E
L
T
K
A
RR
Q
I
G
M
I
F
Q
H
F
N
-
L
L
S
S
R
T
V
F
G
N
V
A
L
---
P
L
------
E
L
-
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
-
K
H
D
S
Y
P
S
N
----
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
E
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
-
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
83
Fugue
60.61
23%
-75
- C2 -
1Z47
1
?
A:
[11-355]
G
S
M
T
I
E
F
V
G
V
E
K
I
Y
P
-
G
G------
A
R
S
V
R
G
V
S
F
Q
-
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
--
G
D
V
W
--
I
--
G
-------
G
K
--
R
V
T
D
L
P
--
P
----
Q
--
K
R
N
-----
V
G
L
V
F
Q
N
Y
A
-
L
F
Q
H
M
T
V
Y
D
N
V
S
F
G
L
R
E
K
------
R
V
----
P
K
D
E
M
D
A
R
V
R
E
L
L
R
F
M
R
L
E
S
-
Y
A
N
R
F
P
H
E
----
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
-
E
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
G
N
V
E
Q
F
-
G
-
T
-
P
E
E
-
V
Y
-
E
K
P
---
G
-
T
L
F
V
---
A
------
S
F
I
-------
G
E
S
N
V
W
-----
T
--
R
A
V
Q
-----
N
G
R
I
E
V
A
G
A
A
L
P
V
D
P
-
A
V
S
E
G
S
E
V
A
V
V
V
R
P
K
D
V
E
L
Q
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
E
R
E
A
H
A
Q
V
V
R
S
A
F
K
G
S
Y
S
A
C
W
I
R
T
K
D
G
----------------------
E
V
W
E
V
H
V
P
S
A
D
R
H
R
W
S
P
G
A
W
V
H
M
N
V
T
R
W
F
I
F
P
R
----------------------------
23
PsiBlast_CBE
60.19
32%
-87
- C2 -
3C4J
4
?
B:
[24-246]
---
M
I
D
V
H
Q
L
K
K
S
F
G
-
S
-------
L
E
V
L
K
G
I
N
V
H
-
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
--
G
E
I
I
--
I
--
D
-------
G
I
NL
K
A
K
D
T
N
--
L
----
N
--
K
V
R
E
---
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
--
P
M
------
K
V
-
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
----
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
-----
G
G
-
Y
-
I
I
E
E
G
-
K
P
-
E
D
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
59.89
32%
-87
- C2 -
2OLK
1
?
D:
[24-246]
---
M
I
D
V
H
Q
L
K
K
S
F
G
-
S
-------
L
E
V
L
K
G
I
N
V
H
-
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
--
G
E
I
I
--
I
--
D
-------
G
I
NL
K
A
K
D
T
N
--
L
----
N
--
K
V
R
E
---
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
--
P
M
------
K
V
-
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
----
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
-----
G
G
-
Y
-
I
I
E
E
G
-
K
P
-
E
D
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
59.73
32%
-91
- C2 -
2OUK
1
?
A:
[24-246]
---
M
I
D
V
H
Q
L
K
K
S
F
G
-
S
-------
L
E
V
L
K
G
I
N
V
H
-
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
--
G
E
I
I
--
I
--
D
-------
G
I
NL
K
A
K
D
T
N
--
L
----
N
--
K
V
R
E
---
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
--
P
M
------
K
V
-
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
----
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
-----
G
G
-
Y
-
I
I
E
E
G
-
K
P
-
E
D
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
59.71
32%
-86
- C2 -
2Q0H
4
?
B:
[24-246]
---
M
I
D
V
H
Q
L
K
K
S
F
G
-
S
-------
L
E
V
L
K
G
I
N
V
H
-
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
--
G
E
I
I
--
I
--
D
-------
G
I
NL
K
A
K
D
T
N
--
L
----
N
--
K
V
R
E
---
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
--
P
M
------
K
V
-
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
----
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
-----
G
G
-
Y
-
I
I
E
E
G
-
K
P
-
E
D
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
74
PsiBlast_CBE
49.91
31%
-87
- C2 -
1XEF
3
HLYBP_ECOLX
C:
[20-214]
----------------------------
D
N
I
N
L
S
-
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
--
G
Q
V
L
--
I
--
D
-------
G
H
--
D
L
A
L
A
D
--
P
----
N
--
W
L
R
R
---
Q
V
G
V
V
L
Q
D
N
V
-
L
L
N
R
-
S
I
I
D
N
I
S
L
A
N
P
G
M
------
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
---
L
R
E
-
G
Y
N
T
I
V
G
E
QGAG
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
---
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
68
PsiBlast_CBE
45.75
31%
-86
- C2 -
2FGJ
2
D:
[26-220]
----------------------------
D
N
I
N
L
S
-
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
--
G
Q
V
L
--
I
--
D
-------
G
H
--
D
L
A
L
A
D
--
P
----
N
--
W
L
R
R
---
Q
V
G
V
V
L
Q
D
N
V
-
L
L
N
R
-
S
I
I
D
N
I
S
L
A
N
P
G
M
------
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
---
L
R
E
-
G
Y
N
T
I
V
G
E
QGAG
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
---
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
70
PsiBlast_CBE
45.60
31%
-81
- C2 -
2FGJ
2
HLYBP_ECOLX
B:
[26-220]
----------------------------
D
N
I
N
L
S
-
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
--
G
Q
V
L
--
I
--
D
-------
G
H
--
D
L
A
L
A
D
--
P
----
N
--
W
L
R
R
---
Q
V
G
V
V
L
Q
D
N
V
-
L
L
N
R
-
S
I
I
D
N
I
S
L
A
N
P
G
M
------
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
---
L
R
E
-
G
Y
N
T
I
V
G
E
QGAG
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
---
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
71
PsiBlast_CBE
44.48
31%
-81
- C2 -
2FGJ
2
HLYBP_ECOLX
A:
[26-220]
----------------------------
D
N
I
N
L
S
-
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
--
G
Q
V
L
--
I
--
D
-------
G
H
--
D
L
A
L
A
D
--
P
----
N
--
W
L
R
R
---
Q
V
G
V
V
L
Q
D
N
V
-
L
L
N
R
-
S
I
I
D
N
I
S
L
A
N
P
G
M
------
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
---
L
R
E
-
G
Y
N
T
I
V
G
E
Q
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
---
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
61
PsiBlast_CBE
44.19
31%
-77
- C2 -
2PMK
1
A:
[22-216]
----------------------------
D
N
I
N
L
S
-
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
--
G
Q
V
L
--
I
--
D
-------
G
H
--
D
L
A
L
A
D
--
P
----
N
--
W
L
R
R
---
Q
V
G
V
V
L
Q
D
N
V
-
L
L
N
R
-
S
I
I
D
N
I
S
L
A
N
P
G
M
------
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
---
L
R
E
-
G
Y
N
T
I
V
G
E
QGAG
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
---
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
59
PsiBlast_CBE
43.96
31%
-76
- C2 -
2FF7
1
A:
[26-220]
----------------------------
D
N
I
N
L
S
-
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
--
G
Q
V
L
--
I
--
D
-------
G
H
--
D
L
A
L
A
D
--
P
----
N
--
W
L
R
R
---
Q
V
G
V
V
L
Q
D
N
V
-
L
L
N
R
-
S
I
I
D
N
I
S
L
A
N
P
G
M
------
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
---
L
R
E
-
G
Y
N
T
I
V
G
E
QGAG
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
---
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
76
PsiBlast_CBE
43.51
31%
-87
- C2 -
1XEF
3
HLYBP_ECOLX
A:
[20-214]
----------------------------
D
N
I
N
L
S
-
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
--
G
Q
V
L
--
I
--
D
-------
G
H
--
D
L
A
L
A
D
--
P
----
N
--
W
L
R
R
---
Q
V
G
V
V
L
Q
D
N
V
-
L
L
N
R
-
S
I
I
D
N
I
S
L
A
N
P
G
M
------
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
---
L
R
E
-
G
Y
N
T
I
V
G
E
QGAG
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
---
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
75
PsiBlast_CBE
42.99
31%
-83
- C2 -
1XEF
3
HLYBP_ECOLX
B:
[20-214]
----------------------------
D
N
I
N
L
S
-
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
--
G
Q
V
L
--
I
--
D
-------
G
H
--
D
L
A
L
A
D
--
P
----
N
--
W
L
R
R
---
Q
V
G
V
V
L
Q
D
N
V
-
L
L
N
R
-
S
I
I
D
N
I
S
L
A
N
P
G
M
------
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
---
L
R
E
-
G
Y
N
T
I
V
G
E
QGAG
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
---
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
62
PsiBlast_CBE
42.68
31%
-75
- C2 -
3B5J
1
A:
[22-216]
----------------------------
D
N
I
N
L
S
-
I
K
Q
G
E
V
I
G
I
V
G
R
A
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
--
G
Q
V
L
--
I
--
D
-------
G
H
--
D
L
A
L
A
D
--
P
----
N
--
W
L
R
R
---
Q
V
G
V
V
L
Q
D
N
V
-
L
L
N
R
-
S
I
I
D
N
I
S
L
A
N
P
G
M
------
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
---
L
R
E
-
G
Y
N
T
I
V
G
E
QG
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
---
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
72
PsiBlast_CBE
41.82
31%
-76
- C2 -
2FFA
2
A:
[26-220]
----------------------------
D
N
I
N
L
S
-
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
--
G
Q
V
L
--
I
--
D
-------
G
H
--
D
L
A
L
A
D
--
P
----
N
--
W
L
R
R
---
Q
V
G
V
V
L
Q
D
N
V
-
L
L
N
R
-
S
I
I
D
N
I
S
L
A
N
P
G
M
------
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
---
L
R
E
-
G
Y
N
T
I
V
G
E
QGAG
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
---
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
64
PsiBlast_CBE
41.67
31%
-78
- C2 -
2FGK
2
HLYBP_ECOLX
C:
[26-220]
----------------------------
D
N
I
N
L
S
-
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
--
G
Q
V
L
--
I
--
D
-------
G
H
--
D
L
A
L
A
D
--
P
----
N
--
W
L
R
R
---
Q
V
G
V
V
L
Q
D
N
V
-
L
L
N
R
-
S
I
I
D
N
I
S
L
A
N
P
G
M
------
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
---
L
R
E
-
G
Y
N
T
I
V
G
E
QGAG
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
---
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
73
PsiBlast_CBE
41.60
31%
-81
- C2 -
1XEF
3
D:
[20-214]
----------------------------
D
N
I
N
L
S
-
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
--
G
Q
V
L
--
I
--
D
-------
G
H
--
D
L
A
L
A
D
--
P
----
N
--
W
L
R
R
---
Q
V
G
V
V
L
Q
D
N
V
-
L
L
N
R
-
S
I
I
D
N
I
S
L
A
N
P
G
M
------
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
---
L
R
E
-
G
Y
N
T
I
V
G
E
QGAG
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
---
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
66
PsiBlast_CBE
41.19
31%
-75
- C2 -
2FGK
2
HLYBP_ECOLX
A:
[26-220]
----------------------------
D
N
I
N
L
S
-
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
--
G
Q
V
L
--
I
--
D
-------
G
H
--
D
L
A
L
A
D
--
P
----
N
--
W
L
R
R
---
Q
V
G
V
V
L
Q
D
N
V
-
L
L
N
R
-
S
I
I
D
N
I
S
L
A
N
P
G
M
------
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
---
L
R
E
-
G
Y
N
T
I
V
G
E
QGAG
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
---
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
69
PsiBlast_CBE
40.41
31%
-81
- C2 -
2FGJ
2
HLYBP_ECOLX
C:
[26-220]
----------------------------
D
N
I
N
L
S
-
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
--
G
Q
V
L
--
I
--
D
-------
G
H
--
D
L
A
L
A
D
--
P
----
N
--
W
L
R
R
---
Q
V
G
V
V
L
Q
D
N
V
-
L
L
N
R
-
S
I
I
D
N
I
S
L
A
N
P
G
M
------
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
---
L
R
E
-
G
Y
N
T
I
V
G
E
QGAG
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
---
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
63
PsiBlast_CBE
39.91
31%
-77
- C2 -
2FGK
2
D:
[26-220]
----------------------------
D
N
I
N
L
S
-
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
--
G
Q
V
L
--
I
--
D
-------
G
H
--
D
L
A
L
A
D
--
P
----
N
--
W
L
R
R
---
Q
V
G
V
V
L
Q
D
N
V
-
L
L
N
R
-
S
I
I
D
N
I
S
L
A
N
P
G
M
------
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
---
L
R
E
-
G
Y
N
T
I
V
G
E
QGAG
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
---
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
65
PsiBlast_CBE
39.19
31%
-73
- C2 -
2FGK
2
HLYBP_ECOLX
B:
[26-220]
----------------------------
D
N
I
N
L
S
-
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
--
G
Q
V
L
--
I
--
D
-------
G
H
--
D
L
A
L
A
D
--
P
----
N
--
W
L
R
R
---
Q
V
G
V
V
L
Q
D
N
V
-
L
L
N
R
-
S
I
I
D
N
I
S
L
A
N
P
G
M
------
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
---
L
R
E
-
G
Y
N
T
I
V
G
E
QGAG
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
---
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------