@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1599: (2016-03-26 )
MNVTIYDVAREANVSMATVSRVVNGNPNVKPVTRKKVLDVINQLGYRPNAVARGLASKRTTTVGVIIPDISNVFYAELARGIEDIATMYKYNIILSNSDENEDKELQVLNTLLGKQVDGIIYMGERISEQLQEEFDRSPAPVVLAGAVDMENKFASVNIDYKQATKEAVKRFVDNGHKQIAFVSGSLNEPVNREMKLAGYKEALEEAGISYQEDYIIEAKYNYNAGVKVWAELSALSKKPNAVVVADDELAIGILNAALDAGIKVPEDLEVMTSNNTKLTLMSRPQLSTIVQPLYDIGAVAMRLLTKLMTSEEVDEKTVILPHSEKLRGTTKEKK
Atome Classification :
(30 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130--........140.......150.......160-.......170.......180.......190........200.......210.......220.......230.....--..240.......250.......260.......270.......280.......290.......300.......310.......320.......330...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
N
V
T
I
Y
D
VAREAN
V
S
M
A
T
V
S
R
V
VNGNPNVKP
V
T
R
K
K
V
L
D
V
I
N
QLGYR
P
N
A
V
A
RGLASKR
T
T
T
V
G
V
I
IPDI
S
N
V
F
Y
A
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
SNSDEN
E
D
K
E
L
Q
V
L
N
T
L
L
GKQVD
G
I
I
Y
M
G
E
R
I
S
E
Q
L
---
Q
E
E
FDRSPA
P
V
V
L
A
G
AVDMENK
F
A
S
V
N
I
D
Y
K
-
Q
A
T
K
E
A
V
K
R
F
V
DNGH
K
Q
I
A
F
VSGSLNEPV-
N
R
E
M
K
L
A
G
Y
K
E
A
L
E
EAGISYQ
E
D
Y
I
I
E
A
K
Y
NYNA
G
V
K
V
W
A
E
L
S
A
LS--KKP
N
A
V
V
V
ADD
E
L
A
I
G
I
L
N
A
A
L
DAGIKVPED
L
E
V
MTSNN
T
K
L
T
L
MSRP
Q
L
S
T
I
V
Q
P
L
Y
D
I
G
A
V
A
M
R
L
L
T
K
L
M
T
S
EEVDE
K
T
V
ILPH
S
E
KLRGTTKEKK
21
PsiBlast_CBE
97.57
65%
-98
- C3 -
3OQO
5
CCPA_BACSU
C:
[1-332]
M
N
I
T
I
Y
D
V
A
R
E
A
N
V
S
M
A
T
V
S
R
V
V
N
G
N
P
N
V
K
P
T
T
R
K
K
V
L
E
A
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
K
K
T
T
T
V
G
V
I
I
P
D
I
S
S
I
F
Y
S
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
M
E
K
E
L
H
L
L
N
T
M
L
G
K
Q
V
D
G
I
V
F
M
G
G
N
I
T
D
E
H
---
V
A
E
F
K
R
S
P
V
P
I
V
L
A
A
S
V
E
E
Q
E
E
T
P
S
V
A
I
D
Y
E
-
Q
A
I
Y
D
A
V
K
L
L
V
D
K
G
H
T
D
I
A
F
V
S
G
P
M
A
E
P
I
-
N
R
S
K
K
L
Q
G
Y
K
R
A
L
E
E
A
N
L
P
F
N
E
Q
F
V
A
E
G
D
Y
T
Y
D
S
G
L
E
A
L
Q
H
L
M
S
L
D
--
K
K
P
T
A
I
L
S
A
T
D
E
M
A
L
G
I
I
H
A
A
Q
D
Q
G
L
S
I
P
E
D
L
D
I
I
G
F
D
N
T
R
L
S
L
M
V
R
P
Q
L
S
T
V
V
Q
P
T
Y
D
I
G
A
V
A
M
R
L
L
T
K
L
M
N
K
E
P
V
E
E
H
I
V
E
L
P
H
R
I
E
L
R
K
S
T
K
---
2
PsiBlast_PDB
97.09
65%
-98
- C3 -
3OQM
4
CCPA_BACSU
A:
[1-332]
M
N
I
T
I
Y
D
V
A
R
E
A
N
V
S
M
A
T
V
S
R
V
V
N
G
N
P
N
V
K
P
T
T
R
K
K
V
L
E
A
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
K
K
T
T
T
V
G
V
I
I
P
D
I
S
S
I
F
Y
S
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
M
E
K
E
L
H
L
L
N
T
M
L
G
K
Q
V
D
G
I
V
F
M
G
G
N
I
T
D
E
H
---
V
A
E
F
K
R
S
P
V
P
I
V
L
A
A
S
V
E
E
Q
E
E
T
P
S
V
A
I
D
Y
E
-
Q
A
I
Y
D
A
V
K
L
L
V
D
K
G
H
T
D
I
A
F
V
S
G
P
M
A
E
P
I
-
N
R
S
K
K
L
Q
G
Y
K
R
A
L
E
E
A
N
L
P
F
N
E
Q
F
V
A
E
G
D
Y
T
Y
D
S
G
L
E
A
L
Q
H
L
M
S
L
D
--
K
K
P
T
A
I
L
S
A
T
D
E
M
A
L
G
I
I
H
A
A
Q
D
Q
G
L
S
I
P
E
D
L
D
I
I
G
F
D
N
T
R
L
S
L
M
V
R
P
Q
L
S
T
V
V
Q
P
T
Y
D
I
G
A
V
A
M
R
L
L
T
K
L
M
N
K
E
P
V
E
E
H
I
V
E
L
P
H
R
I
E
L
R
K
S
T
K
---
23
PsiBlast_CBE
96.89
65%
-97
- C3 -
3OQM
4
CCPA_BACSU
C:
[1-332]
M
N
I
T
I
Y
D
V
A
R
E
A
N
V
S
M
A
T
V
S
R
V
V
N
G
N
P
N
V
K
P
T
T
R
K
K
V
L
E
A
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
K
K
T
T
T
V
G
V
I
I
P
D
I
S
S
I
F
Y
S
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
M
E
K
E
L
H
L
L
N
T
M
L
G
K
Q
V
D
G
I
V
F
M
G
G
N
I
T
D
E
H
---
V
A
E
F
K
R
S
P
V
P
I
V
L
A
A
S
V
E
E
Q
E
E
T
P
S
V
A
I
D
Y
E
-
Q
A
I
Y
D
A
V
K
L
L
V
D
K
G
H
T
D
I
A
F
V
S
G
P
M
A
E
P
I
-
N
R
S
K
K
L
Q
G
Y
K
R
A
L
E
E
A
N
L
P
F
N
E
Q
F
V
A
E
G
D
Y
T
Y
D
S
G
L
E
A
L
Q
H
L
M
S
L
D
--
K
K
P
T
A
I
L
S
A
T
D
E
M
A
L
G
I
I
H
A
A
Q
D
Q
G
L
S
I
P
E
D
L
D
I
I
G
F
D
N
T
R
L
S
L
M
V
R
P
Q
L
S
T
V
V
Q
P
T
Y
D
I
G
A
V
A
M
R
L
L
T
K
L
M
N
K
E
P
V
E
E
H
I
V
E
L
P
H
R
I
E
L
R
K
S
T
K
---
3
PsiBlast_PDB
96.50
65%
-102
- C3 -
3OQN
2
CCPA_BACSU
A:
[1-332]
M
N
I
T
I
Y
D
V
A
R
E
A
N
V
S
M
A
T
V
S
R
V
V
N
G
N
P
N
V
K
P
T
T
R
K
K
V
L
E
A
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
K
K
T
T
T
V
G
V
I
I
P
D
I
S
S
I
F
Y
S
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
M
E
K
E
L
H
L
L
N
T
M
L
G
K
Q
V
D
G
I
V
F
M
G
G
N
I
T
D
E
H
---
V
A
E
F
K
R
S
P
V
P
I
V
L
A
A
S
V
E
E
Q
E
E
T
P
S
V
A
I
D
Y
E
-
Q
A
I
Y
D
A
V
K
L
L
V
D
K
G
H
T
D
I
A
F
V
S
G
P
M
A
E
P
I
-
N
R
S
K
K
L
Q
G
Y
K
R
A
L
E
E
A
N
L
P
F
N
E
Q
F
V
A
E
G
D
Y
T
Y
D
S
G
L
E
A
L
Q
H
L
M
S
L
D
--
K
K
P
T
A
I
L
S
A
T
D
E
M
A
L
G
I
I
H
A
A
Q
D
Q
G
L
S
I
P
E
D
L
D
I
I
G
F
D
N
T
R
L
S
L
M
V
R
P
Q
L
S
T
V
V
Q
P
T
Y
D
I
G
A
V
A
M
R
L
L
T
K
L
M
N
K
E
P
V
E
E
H
I
V
E
L
P
H
R
I
E
L
R
K
S
T
K
---
1
PsiBlast_PDB
96.32
65%
-98
- C3 -
3OQO
4
CCPA_BACSU
A:
[1-332]
M
N
I
T
I
Y
D
V
A
R
E
A
N
V
S
M
A
T
V
S
R
V
V
N
G
N
P
N
V
K
P
T
T
R
K
K
V
L
E
A
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
K
K
T
T
T
V
G
V
I
I
P
D
I
S
S
I
F
Y
S
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
M
E
K
E
L
H
L
L
N
T
M
L
G
K
Q
V
D
G
I
V
F
M
G
G
N
I
T
D
E
H
---
V
A
E
F
K
R
S
P
V
P
I
V
L
A
A
S
V
E
E
Q
E
E
T
P
S
V
A
I
D
Y
E
-
Q
A
I
Y
D
A
V
K
L
L
V
D
K
G
H
T
D
I
A
F
V
S
G
P
M
A
E
P
I
-
N
R
S
K
K
L
Q
G
Y
K
R
A
L
E
E
A
N
L
P
F
N
E
Q
F
V
A
E
G
D
Y
T
Y
D
S
G
L
E
A
L
Q
H
L
M
S
L
D
--
K
K
P
T
A
I
L
S
A
T
D
E
M
A
L
G
I
I
H
A
A
Q
D
Q
G
L
S
I
P
E
D
L
D
I
I
G
F
D
N
T
R
L
S
L
M
V
R
P
Q
L
S
T
V
V
Q
P
T
Y
D
I
G
A
V
A
M
R
L
L
T
K
L
M
N
K
E
P
V
E
E
H
I
V
E
L
P
H
R
I
E
L
R
K
S
T
K
---
22
PsiBlast_CBE
96.25
65%
-97
- C3 -
3OQN
2
CCPA_BACSU
C:
[1-332]
M
N
I
T
I
Y
D
V
A
R
E
A
N
V
S
M
A
T
V
S
R
V
V
N
G
N
P
N
V
K
P
T
T
R
K
K
V
L
E
A
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
K
K
T
T
T
V
G
V
I
I
P
D
I
S
S
I
F
Y
S
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
M
E
K
E
L
H
L
L
N
T
M
L
G
K
Q
V
D
G
I
V
F
M
G
G
N
I
T
D
E
H
---
V
A
E
F
K
R
S
P
V
P
I
V
L
A
A
S
V
E
E
Q
E
E
T
P
S
V
A
I
D
Y
E
-
Q
A
I
Y
D
A
V
K
L
L
V
D
K
G
H
T
D
I
A
F
V
S
G
P
M
A
E
P
I
-
N
R
S
K
K
L
Q
G
Y
K
R
A
L
E
E
A
N
L
P
F
N
E
Q
F
V
A
E
G
D
Y
T
Y
D
S
G
L
E
A
L
Q
H
L
M
S
L
D
--
K
K
P
T
A
I
L
S
A
T
D
E
M
A
L
G
I
I
H
A
A
Q
D
Q
G
L
S
I
P
E
D
L
D
I
I
G
F
D
N
T
R
L
S
L
M
V
R
P
Q
L
S
T
V
V
Q
P
T
Y
D
I
G
A
V
A
M
R
L
L
T
K
L
M
N
K
E
P
V
E
E
H
I
V
E
L
P
H
R
I
E
L
R
K
S
T
K
---
5
PsiBlast_PDB
94.40
62%
-99
- C3 -
1ZVV
4
CCPA_BACSU
A:
[1-332]
M
N
V
T
I
Y
D
V
A
R
E
A
S
V
S
M
A
T
V
S
R
V
V
N
G
N
P
N
V
K
P
S
T
R
K
K
V
L
E
T
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
K
K
T
T
T
V
G
V
I
I
P
D
I
S
N
I
F
Y
A
E
L
A
R
G
I
E
D
I
A
S
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
Q
D
K
Q
L
H
L
L
N
N
M
L
G
K
Q
V
D
G
I
I
F
M
S
G
N
V
T
E
E
H
---
V
E
E
L
K
K
S
P
V
P
V
V
L
A
A
S
I
E
S
T
N
Q
I
P
S
V
T
I
D
Y
E
-
Q
A
A
F
D
A
V
Q
S
L
I
D
S
G
H
K
N
I
A
F
V
S
G
T
L
E
E
P
I
-
N
H
A
K
K
V
K
G
Y
K
R
A
L
T
E
S
G
L
P
V
R
D
S
Y
I
V
E
G
D
Y
T
Y
D
S
G
I
E
A
V
E
K
L
L
E
E
D
--
E
K
P
T
A
I
F
V
G
T
D
E
M
A
L
G
V
I
H
G
A
Q
D
R
G
L
N
V
P
N
D
L
E
I
I
G
F
D
N
T
R
L
S
T
M
V
R
P
Q
L
T
S
V
V
Q
P
M
Y
D
I
G
A
V
A
M
R
L
L
T
K
Y
M
N
K
E
T
V
D
S
S
I
V
E
L
P
H
R
I
E
F
R
Q
S
T
K
---
6
PsiBlast_PDB
94.02
60%
-96
- C3 -
1RZR
5
CCPA_BACME
D:
[1-332]
M
N
V
T
I
Y
D
V
A
R
E
A
S
V
S
M
A
T
V
S
R
V
V
N
G
N
P
N
V
K
P
S
T
R
K
K
V
L
E
T
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
K
K
T
T
T
V
G
V
I
I
P
D
I
S
N
I
F
Y
A
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
Q
D
K
E
L
H
L
L
N
N
M
L
G
K
Q
V
D
G
I
I
F
M
S
G
N
V
T
E
E
H
---
V
E
E
L
K
K
S
P
V
P
V
V
L
A
A
S
I
E
S
T
N
Q
I
P
S
V
T
I
D
Y
E
-
Q
A
A
F
D
A
V
Q
S
L
I
D
S
G
H
K
N
I
A
F
V
S
G
T
L
E
E
P
I
-
N
H
A
K
K
V
K
G
Y
K
R
A
L
T
E
S
G
L
P
V
R
D
S
Y
I
V
E
G
D
Y
T
Y
D
S
G
I
E
A
V
E
K
L
L
E
E
D
--
E
K
P
T
A
I
F
V
G
T
D
E
M
A
L
G
V
I
H
G
A
Q
D
R
G
L
N
V
P
N
D
L
E
I
I
G
F
D
N
T
R
L
S
T
M
V
R
P
Q
L
T
S
V
V
Q
P
M
Y
D
I
G
A
V
A
M
R
L
L
T
K
Y
M
N
K
E
T
V
D
S
S
I
V
Q
L
P
H
R
I
E
F
R
Q
S
T
K
---
24
PsiBlast_CBE
93.88
62%
-95
- C3 -
1ZVV
3
CCPA_BACSU
G:
[1-332]
M
N
V
T
I
Y
D
V
A
R
E
A
S
V
S
M
A
T
V
S
R
V
V
N
G
N
P
N
V
K
P
S
T
R
K
K
V
L
E
T
I
E
---
Y
R
P
N
A
V
A
R
G
L
A
S
K
K
T
T
T
V
G
V
I
I
P
D
I
S
N
I
F
Y
A
E
L
A
R
G
I
E
D
I
A
S
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
Q
D
K
Q
L
H
L
L
N
N
M
L
G
K
Q
V
D
G
I
I
F
M
S
G
N
V
T
E
E
H
---
V
E
E
L
K
K
S
P
V
P
V
V
L
A
A
S
I
E
S
T
N
Q
I
P
S
V
T
I
D
Y
E
-
Q
A
A
F
D
A
V
Q
S
L
I
D
S
G
H
K
N
I
A
F
V
S
G
T
L
E
E
P
I
-
N
H
A
K
K
V
K
G
Y
K
R
A
L
T
E
S
G
L
P
V
R
D
S
Y
I
V
E
G
D
Y
T
Y
D
S
G
I
E
A
V
E
K
L
L
E
E
D
--
E
K
P
T
A
I
F
V
G
T
D
E
M
A
L
G
V
I
H
G
A
Q
D
R
G
L
N
V
P
N
D
L
E
I
I
G
F
D
N
T
R
L
S
T
M
V
R
P
Q
L
T
S
V
V
Q
P
M
Y
D
I
G
A
V
A
M
R
L
L
T
K
Y
M
N
K
E
T
V
D
S
S
I
V
E
L
P
H
R
I
E
F
R
Q
S
T
K
---
25
PsiBlast_CBE
93.70
62%
-95
- C3 -
1ZVV
6
CCPA_BACSU
B:
[1-332]
M
N
V
T
I
Y
D
V
A
R
E
A
S
V
S
M
A
T
V
S
R
V
V
N
G
N
P
N
V
K
P
S
T
R
K
K
V
L
E
T
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
K
K
T
T
T
V
G
V
I
I
P
D
I
S
N
I
F
Y
A
E
L
A
R
G
I
E
D
I
A
S
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
Q
D
K
Q
L
H
L
L
N
N
M
L
G
K
Q
V
D
G
I
I
F
M
S
G
N
V
T
E
E
H
---
V
E
E
L
K
K
S
P
V
P
V
V
L
A
A
S
I
E
S
T
N
Q
I
P
S
V
T
I
D
Y
E
-
Q
A
A
F
D
A
V
Q
S
L
I
D
S
G
H
K
N
I
A
F
V
S
G
T
L
E
E
P
I
-
N
H
A
K
K
V
K
G
Y
K
R
A
L
T
E
S
G
L
P
V
R
D
S
Y
I
V
E
G
D
Y
T
Y
D
S
G
I
E
A
V
E
K
L
L
E
E
D
--
E
K
P
T
A
I
F
V
G
T
D
E
M
A
L
G
V
I
H
G
A
Q
D
R
G
L
N
V
P
N
D
L
E
I
I
G
F
D
N
T
R
L
S
T
M
V
R
P
Q
L
T
S
V
V
Q
P
M
Y
D
I
G
A
V
A
M
R
L
L
T
K
Y
M
N
K
E
T
V
D
S
S
I
V
E
L
P
H
R
I
E
F
R
Q
S
T
K
---
60
HHSearch
90.62
63%
-90
- C3 -
2HSG
-
CCPA_BACME
A:
[2-332]
-
N
V
T
I
Y
D
V
A
R
E
A
S
V
S
M
A
T
V
S
R
V
V
N
G
N
P
N
V
K
P
S
T
R
K
K
V
L
E
T
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
-
K
T
T
T
V
G
V
I
I
P
--
S
N
I
F
Y
A
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
Q
D
K
E
L
H
L
L
N
N
M
L
G
K
Q
V
D
G
I
I
F
M
S
G
N
V
T
E
E
H
---
V
E
E
L
K
K
S
P
V
P
V
V
L
A
A
S
I
E
S
T
N
Q
I
P
S
V
T
I
D
Y
E
-
Q
A
A
F
D
A
V
Q
S
L
I
D
S
G
H
K
N
I
A
F
V
S
G
T
L
E
E
-
P
I
N
H
A
K
K
V
K
G
Y
K
R
A
L
T
E
S
G
L
P
V
R
D
S
Y
I
V
E
G
D
Y
T
Y
D
S
G
I
E
A
V
E
K
--
L
L
E
ED
E
K
P
T
A
I
F
V
G
T
D
E
M
A
L
G
V
I
H
G
A
Q
D
R
G
L
N
V
P
N
D
L
E
I
I
G
F
D
N
T
R
L
S
T
M
V
R
P
Q
L
T
S
V
V
Q
P
M
Y
D
I
G
A
V
A
M
R
L
L
T
K
Y
M
N
K
E
T
V
D
S
S
I
V
Q
L
P
H
R
I
E
F
R
Q
S
T
K
---
4
PsiBlast_PDB
90.48
62%
-88
- C3 -
2HSG
-
CCPA_BACME
A:
[2-332]
-
N
V
T
I
Y
D
V
A
R
E
A
S
V
S
M
A
T
V
S
R
V
V
N
G
N
P
N
V
K
P
S
T
R
K
K
V
L
E
T
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
-
K
T
T
T
V
G
V
I
I
P
--
S
N
I
F
Y
A
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
Q
D
K
E
L
H
L
L
N
N
M
L
G
K
Q
V
D
G
I
I
F
M
S
G
N
V
T
E
E
H
---
V
E
E
L
K
K
S
P
V
P
V
V
L
A
A
S
I
E
S
T
N
Q
I
P
S
V
T
I
D
Y
E
-
Q
A
A
F
D
A
V
Q
S
L
I
D
S
G
H
K
N
I
A
F
V
S
G
T
L
E
E
P
I
-
N
H
A
K
K
V
K
G
Y
K
R
A
L
T
E
S
G
L
P
V
R
D
S
Y
I
V
E
G
D
Y
T
Y
D
S
G
I
E
A
V
E
K
L
L
E
E
D
--
E
K
P
T
A
I
F
V
G
T
D
E
M
A
L
G
V
I
H
G
A
Q
D
R
G
L
N
V
P
N
D
L
E
I
I
G
F
D
N
T
R
L
S
T
M
V
R
P
Q
L
T
S
V
V
Q
P
M
Y
D
I
G
A
V
A
M
R
L
L
T
K
Y
M
N
K
E
T
V
D
S
S
I
V
Q
L
P
H
R
I
E
F
R
Q
S
T
K
---
7
PsiBlast_PDB
86.64
60%
-98
- C3 -
2FEP
2
CCPA_BACSU
A:
[16-288]
-----------------------------------------------------------
T
T
T
V
G
V
I
I
P
D
I
S
S
I
F
Y
S
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
M
E
K
E
L
H
L
L
N
T
M
L
G
K
Q
V
D
G
I
V
F
M
G
G
N
I
T
D
E
H
---
V
A
E
F
K
R
S
P
V
P
I
V
L
A
A
S
V
E
E
Q
E
E
T
P
S
V
A
I
D
Y
E
-
Q
A
I
Y
D
A
V
K
L
L
V
D
K
G
H
T
D
I
A
F
V
S
G
P
M
A
E
P
I
-
N
R
S
K
K
L
Q
G
Y
K
R
A
L
E
E
A
N
L
P
F
N
E
Q
F
V
A
E
G
D
Y
T
Y
D
S
G
L
E
A
L
Q
H
L
M
S
L
D
--
K
K
P
T
A
I
L
S
A
T
D
E
M
A
L
G
I
I
H
A
A
Q
D
Q
G
L
S
I
P
E
D
L
D
I
I
G
F
D
N
T
R
L
S
L
M
V
R
P
Q
L
S
T
V
V
Q
P
T
Y
D
I
G
A
V
A
M
R
L
L
T
K
L
M
N
K
E
P
V
E
E
H
I
V
E
L
P
H
R
I
E
L
R
K
S
T
K
---
73
HHSearch
86.46
60%
-100
- C3 -
2FEP
2
CCPA_BACSU
A:
[16-288]
-----------------------------------------------------------
T
T
T
V
G
V
I
I
P
D
I
S
S
I
F
Y
S
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
M
E
K
E
L
H
L
L
N
T
M
L
G
K
Q
V
D
G
I
V
F
M
G
G
N
I
T
D
E
H
---
V
A
E
F
K
R
S
P
V
P
I
V
L
A
A
S
V
E
E
Q
E
E
T
P
S
V
A
I
D
Y
E
-
Q
A
I
Y
D
A
V
K
L
L
V
D
K
G
H
T
D
I
A
F
V
S
G
P
M
A
E
P
I
-
N
R
S
K
K
L
Q
G
Y
K
R
A
L
E
E
A
N
L
P
F
N
E
Q
F
V
A
E
G
D
Y
T
Y
D
S
G
L
E
A
L
Q
H
--
L
M
S
LD
K
K
P
T
A
I
L
S
A
T
D
E
M
A
L
G
I
I
H
A
A
Q
D
Q
G
L
S
I
P
E
D
L
D
I
I
G
F
D
N
T
R
L
S
L
M
V
R
P
Q
L
S
T
V
V
Q
P
T
Y
D
I
G
A
V
A
M
R
L
L
T
K
L
M
N
K
E
P
V
E
E
H
I
V
E
L
P
H
R
I
E
L
R
K
S
T
K
---
9
PsiBlast_PDB
86.04
57%
-97
- C3 -
2NZU
8
CCPA_BACME
G:
[6-280]
---------------------------------------------------------
K
K
T
T
T
V
G
V
I
I
P
D
I
S
N
I
F
Y
A
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
Q
D
K
E
L
H
L
L
N
N
M
L
G
K
Q
V
D
G
I
I
F
M
S
G
N
V
T
E
E
H
---
V
E
E
L
K
K
S
P
V
P
V
V
L
A
A
S
I
E
S
T
N
Q
I
P
S
V
T
I
D
Y
E
-
Q
A
A
F
D
A
V
Q
S
L
I
D
S
G
H
K
N
I
A
F
V
S
G
T
L
E
E
P
I
-
N
H
A
K
K
V
K
G
Y
K
R
A
L
T
E
S
G
L
P
V
R
D
S
Y
I
V
E
G
D
Y
T
Y
D
S
G
I
E
A
V
E
K
L
L
E
E
D
--
E
K
P
T
A
I
F
V
G
T
D
E
M
A
L
G
V
I
H
G
A
Q
D
R
G
L
N
V
P
N
D
L
E
I
I
G
F
D
N
T
R
L
S
T
M
V
R
P
Q
L
T
S
V
V
Q
P
M
Y
D
I
G
A
V
A
M
R
L
L
T
K
Y
M
N
K
E
T
V
D
S
S
I
V
Q
L
P
H
R
I
E
F
R
Q
S
T
K
---
10
PsiBlast_PDB
85.58
57%
-99
- C3 -
2NZV
6
CCPA_BACME
G:
[6-280]
---------------------------------------------------------
K
K
T
T
T
V
G
V
I
I
P
D
I
S
N
I
F
Y
A
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
Q
D
K
E
L
H
L
L
N
N
M
L
G
K
Q
V
D
G
I
I
F
M
S
G
N
V
T
E
E
H
---
V
E
E
L
K
K
S
P
V
P
V
V
L
A
A
S
I
E
S
T
N
Q
I
P
S
V
T
I
D
Y
E
-
Q
A
A
F
D
A
V
Q
S
L
I
D
S
G
H
K
N
I
A
F
V
S
G
T
L
E
E
P
I
-
N
H
A
K
K
V
K
G
Y
K
R
A
L
T
E
S
G
L
P
V
R
D
S
Y
I
V
E
G
D
Y
T
Y
D
S
G
I
E
A
V
E
K
L
L
E
E
D
--
E
K
P
T
A
I
F
V
G
T
D
E
M
A
L
G
V
I
H
G
A
Q
D
R
G
L
N
V
P
N
D
L
E
I
I
G
F
D
N
T
R
L
S
T
M
V
R
P
Q
L
T
S
V
V
Q
P
M
Y
D
I
G
A
V
A
M
R
L
L
T
K
Y
M
N
K
E
T
V
D
S
S
I
V
Q
L
P
H
R
I
E
F
R
Q
S
T
K
---
26
PsiBlast_CBE
84.15
57%
-92
- C3 -
1SXG
1
CCPA_BACME
B:
[8-280]
-----------------------------------------------------------
T
T
T
V
G
V
I
I
P
D
I
S
N
I
F
Y
A
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
Q
D
K
E
L
H
L
L
N
N
M
L
G
K
Q
V
D
G
I
I
F
M
S
G
N
V
T
E
E
H
---
V
E
E
L
K
K
S
P
V
P
V
V
L
A
A
S
I
E
S
T
N
Q
I
P
S
V
T
I
D
Y
E
-
Q
A
A
F
D
A
V
Q
S
L
I
D
S
G
H
K
N
I
A
F
V
S
G
T
L
E
E
P
I
-
N
H
A
K
K
V
K
G
Y
K
R
A
L
T
E
S
G
L
P
V
R
D
S
Y
I
V
E
G
D
Y
T
Y
D
S
G
I
E
A
V
E
K
L
L
E
E
D
--
E
K
P
T
A
I
F
V
G
T
D
E
M
A
L
G
V
I
H
G
A
Q
D
R
G
L
N
V
P
N
D
L
E
I
I
G
F
D
N
T
R
L
S
T
M
V
R
P
Q
L
T
S
V
V
Q
P
M
Y
D
I
G
A
V
A
M
R
L
L
T
K
Y
M
N
K
E
T
V
D
S
S
I
V
Q
L
P
H
R
I
E
F
R
Q
S
T
K
---
8
PsiBlast_PDB
83.55
57%
-89
- C3 -
1SXG
1
CCPA_BACME
A:
[6-280]
---------------------------------------------------------
K
K
T
T
T
V
G
V
I
I
P
D
I
S
N
I
F
Y
A
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
Q
D
K
E
L
H
L
L
N
N
M
L
G
K
Q
V
D
G
I
I
F
M
S
G
N
V
T
E
E
H
---
V
E
E
L
K
K
S
P
V
P
V
V
L
A
A
S
I
E
S
T
N
Q
I
P
S
V
T
I
D
Y
E
-
Q
A
A
F
D
A
V
Q
S
L
I
D
S
G
H
K
N
I
A
F
V
S
G
T
L
E
E
P
I
-
N
H
A
K
K
V
K
G
Y
K
R
A
L
T
E
S
G
L
P
V
R
D
S
Y
I
V
E
G
D
Y
T
Y
D
S
G
I
E
A
V
E
K
L
L
E
E
D
--
E
K
P
T
A
I
F
V
G
T
D
E
M
A
L
G
V
I
H
G
A
Q
D
R
G
L
N
V
P
N
D
L
E
I
I
G
F
D
N
T
R
L
S
T
M
V
R
P
Q
L
T
S
V
V
Q
P
M
Y
D
I
G
A
V
A
M
R
L
L
T
K
Y
M
N
K
E
T
V
D
S
S
I
V
Q
L
P
H
R
I
E
F
R
Q
S
T
K
---
14
PsiBlast_PDB
83.19
56%
-92
- C3 -
1SXI
-
CCPA_BACME
A:
[8-280]
-----------------------------------------------------------
T
T
T
V
G
V
I
I
P
D
I
S
N
I
F
Y
A
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
Q
D
K
E
L
H
L
L
N
N
M
L
G
K
Q
V
D
G
I
I
F
M
S
G
N
V
T
E
E
H
---
V
E
E
L
K
K
S
P
V
P
V
V
L
A
A
S
I
E
S
T
N
Q
I
P
S
V
T
I
D
Y
E
-
Q
A
A
F
D
A
V
Q
S
L
I
D
S
G
H
K
N
I
A
F
V
S
G
T
L
E
E
P
I
-
N
H
A
K
K
V
K
G
Y
K
R
A
L
T
E
S
G
L
P
V
R
D
S
Y
I
V
E
G
D
Y
T
Y
D
S
G
I
E
A
V
E
K
L
L
E
E
D
--
E
K
P
T
A
I
F
V
G
T
D
E
M
A
L
G
V
I
H
G
A
Q
D
R
G
L
N
V
P
N
D
L
E
I
I
G
F
D
N
T
R
L
S
T
M
V
R
P
Q
L
T
S
V
V
Q
P
M
Y
D
I
G
A
V
A
M
R
L
L
T
K
Y
M
N
K
E
T
V
D
S
S
I
V
Q
L
P
H
R
I
E
F
R
Q
S
T
K
---
11
PsiBlast_PDB
82.90
57%
-97
- C3 -
2OEN
-
CCPA_BACME
G:
[58-332]
---------------------------------------------------------
K
K
T
T
T
V
G
V
I
I
P
D
I
S
N
I
F
Y
A
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
Q
D
K
E
L
H
L
L
N
N
M
L
G
K
Q
V
D
G
I
I
F
M
S
G
N
V
T
E
E
H
---
V
E
E
L
K
K
S
P
V
P
V
V
L
A
A
S
I
E
S
T
N
Q
I
P
S
V
T
I
D
Y
E
-
Q
A
A
F
D
A
V
Q
S
L
I
D
S
G
H
K
N
I
A
F
V
S
G
T
L
E
E
P
I
-
N
H
A
K
K
V
K
G
Y
K
R
A
L
T
E
S
G
L
P
V
R
D
S
Y
I
V
E
G
D
Y
T
Y
D
S
G
I
E
A
V
E
K
L
L
E
E
D
--
E
K
P
T
A
I
F
V
G
T
D
E
M
A
L
G
V
I
H
G
A
Q
D
R
G
L
N
V
P
N
D
L
E
I
I
G
F
D
N
T
R
L
S
T
M
V
R
P
Q
L
T
S
V
V
Q
P
M
Y
D
I
G
A
V
A
M
R
L
L
T
K
Y
M
N
K
E
T
V
D
S
S
I
V
Q
L
P
H
R
I
E
F
R
Q
S
T
K
---
19
PsiBlast_PDB
72.28
31%
-91
- C3 -
1JFT
3
PURR_ECOLI
A:
[2-304]
---
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
E
Y
R
H
I
P
M
V
V
M
D
A
G
--
E
A
K
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
R
N
T
-
G
-
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
--
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
------------------------------
32
PsiBlast_CBE
71.10
31%
-89
- C3 -
2PUC
2
PURR_ECOLI
A:
[2-304]
---
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
E
Y
R
H
I
P
M
V
V
M
D
W
G
--
E
A
K
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
-
E
A
N
-
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
--
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
------------------------------
31
PsiBlast_CBE
70.56
31%
-88
- C3 -
2PUD
2
PURR_ECOLI
A:
[2-304]
---
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
E
Y
R
H
I
P
M
V
V
M
D
W
G
--
E
A
K
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
-
E
A
N
-
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
--
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
------------------------------
34
PsiBlast_CBE
70.40
31%
-87
- C3 -
2PUA
2
PURR_ECOLI
A:
[2-304]
---
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
E
Y
R
H
I
P
M
V
V
M
D
W
G
--
E
A
K
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
-
E
A
N
-
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
--
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
------------------------------
16
PsiBlast_PDB
70.25
31%
-90
- C3 -
1QP7
2
PURR_ECOLI
A:
[2-304]
---
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
A
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
E
Y
R
H
I
P
M
V
V
M
D
W
G
--
E
A
K
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
R
N
T
-
G
-
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
--
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
------------------------------
33
PsiBlast_CBE
70.07
31%
-90
- C3 -
2PUB
2
PURR_ECOLI
A:
[2-304]
---
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
E
Y
R
H
I
P
M
V
V
M
D
W
G
--
E
A
K
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
-
E
A
N
-
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
--
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
------------------------------
15
PsiBlast_PDB
70.07
31%
-91
- C3 -
1BDH
2
PURR_ECOLI
A:
[2-304]
---
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
A
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
E
Y
R
H
I
P
M
V
V
M
D
W
G
--
E
A
K
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
R
N
T
-
G
-
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
--
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
------------------------------
18
PsiBlast_PDB
69.93
31%
-87
- C3 -
1QQB
2
PURR_ECOLI
A:
[2-304]
---
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
A
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
E
Y
R
H
I
P
M
V
V
M
D
W
G
--
E
A
K
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
R
N
T
-
G
-
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
--
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
------------------------------
20
PsiBlast_PDB
69.41
30%
-88
- C3 -
2PUE
2
PURR_ECOLI
A:
[2-304]
---
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
E
Y
R
H
I
P
M
V
V
M
D
W
G
--
E
A
K
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
Q
N
T
-
G
-
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
--
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
------------------------------
17
PsiBlast_PDB
69.09
31%
-87
- C3 -
1QQA
2
PURR_ECOLI
A:
[2-304]
---
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
A
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
E
Y
R
H
I
P
M
V
V
M
D
W
G
--
E
A
K
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
R
N
T
-
G
-
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
--
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
------------------------------