@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0293: (2015-11-30 )
MSEDQKHPFFEPKKETDGLEFKDAKEMTVEEAVRKDSEIKAGITEEDSILDKYIKQHRDEVASQKFETKSSDFANLDTASLDDFIKKQREELSAMLAAEELSKKLDNSVSQEQDTEANAVSPKEESSQEQENSVTPVPPLNTEAEPTATEPDSTIADSEEYKSSSKKRGGIVGTLIALILLLIVAIFGYNYFKNNNSTNSQTATSQSSSSKATTTSSEEDKKASQNLDNFNKSYANFFVDDKKTQLKNSEFDKLSELEKKVDALKGTKYYGKVKVKFDSLKRQIDAVKAVNDKFKSPAVVDGKKSEKLEVKDGANFDSLDSKTLNTGNASLDSLLHSIVSTGRNQVKQSEEQASSNKVSDTQITEQPNVTNGQSSSSAATINNQAAGTASGNLERNRSRVPYNNAAIADTGNPAWIFNPGVLEKIVATSQARGYFSGNNYILEPVNIINGNGYYNMFKLDGTYLFSINAKTGYFVGNAPGRADSLDY
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70...-.....80........90........100.......110.......120.......130.......140.......150.......160.......170.......-----180.......190.......200.......210....--...220.......230-.......240....------...250.......260---------....-----...270.....-..280.-......290..---.....300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430....---...440.......450....---....460---------------........470.......480.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MSEDQKHPFFEPKKETDGLEFK
D
A
K
E
M
T
V
E
E
A
V
RKD
S
E
IKAGIT
E
E
D
S
I
L
D
K
Y
I
K
Q
H
R
D
E
V
A
S
Q
KFETKSSDFA-NL
D
T
A
S
L
D
D
F
I
K
K
Q
R
E
E
L
S
A
M
L
A
A
E
E
L
S
K
K
LDNSVSQEQDTEANAVSPKEESSQEQENSVTPVPPLNTEAEPTATEPDSTIA
D
S
E
E
Y
K
SSSKKRG
G
I
V
G
T
L
I
A
L
I
-----
L
L
L
I
V
A
I
FGY
N
Y
FKNNNSTNSQTATSQSSSSKATTTS--S
E
E
D
K
K
A
SQN
L
D
N
F
N
K
-
S
Y
A
N
F
F
VDD
K
K
TQL------KNS
E
F
D
K
L
S
E
L
E
K
K
V
D
---------
A
LKG-----T
K
Y
Y
G
K
V
K
V
K
F
-
D
S
L
K
R
Q
-
I
D
A
V
K
A
V
N
D
KF---KSPAVVDGKKS
E
K
L
E
VKDGANFDSLDSKTLNTGN
A
S
L
D
S
L
L
H
S
I
V
S
T
G
R
N
Q
V
K
Q
S
E
E
QASSNKVSDTQITEQPNVTNGQSSSS
A
A
T
INNQAAGTASGNLERNRSRVPYNNAAIADTGN
P
A
W
I
F
N
P
G
V
L
E
K
I
V
A
TSQA
R
G
Y
FS---GN
N
Y
I
L
E
P
V
N
I
INGN-G
Y
Y
N
---
M
F
K
LD
G
----------------
T
Y
L
F
S
I
NAK
T
G
Y
F
VGNAPGRADSLDY
3
PsiBlast_PDB
86.97
21%
41
- C3 -
1CII
-
CEIA_ECOLX
A:
[176-474]
-----------
P
R
E
A
R
S
L
I
E
Q
A
E
K
R
Q
K
D
A
Q
N
A
D
K
K
A
A
D
M
L
A
E
Y
E
R
R
K
G
I
L
D
T
R
L
--------
S
E
L
E
K
N
G
G
A
A
L
A
-
V
L
D
A
Q
Q
A
R
L
L
G
Q
Q
T
R
N
D
R
A
I
S
E
A
R
N
K
L
S
-----
S
V
T
E
S
L
N
T
A
R
N
A
L
T
R
A
E
Q
Q
L
T
Q
Q
K
N
T
----
P
D
G
K
T
I
V
S
P
E
K
F
P
G
R
S
S
T
N
D
S
I
V
V
S
G
D
P
R
F
A
G
T
I
K
I
T
T
S
A
V
I
D
N
R
A
N
L
N
Y
L
L
S
H
S
G
L
D
Y
K
R
N
I
L
N
D
R
N
P
V
V
T
E
D
V
E
G
D
K
K
I
Y
N
A
E
V
A
E
W
D
K
L
R
Q
R
L
L
D
A
R
N
K
I
T
S
A
E
S
A
V
N
S
A
R
N
N
L
S
A
R
T
N
E
Q
K
H
A
N
D
A
L
N
A
L
L
K
E
K
E
---------
N
I
R
N
Q
L
S
G
I
N
Q
K
I
A
E
E
K
R
K
Q
-
D
E
L
K
A
T
-
K
D
A
I
N
F
T
T
E
F
L
---
K
S
V
S
E
K
Y
G
A
K
A
E
Q
L
A
R
E
M
A
G
Q
A
K
G
K
K
I
R
N
V
E
E
A
L
K
T
Y
E
K
Y
R
A
D
I
N
K
K
I
N
A
K
D
R
A
A
I
A
A
A
L
E
S
V
K
L
S
D
I
S
S
N
L
N
R
F
S
R
G
L
G
Y
A
G
K
F
T
S
L
A
D
W
I
T
E
F
G
K
A
V
R
T
E
N
W
R
P
L
F
V
K
T
E
T
I
I
A
G
N
A
A
T
A
L
V
A
L
V
F
S
I
L
T
G
S
A
L
G
I
I
G
Y
G
---
L
L
M
A
V
T
G
A
L
I
D
E
S
L
V
-
E
K
A
N
---
K
F
W
---------------------------------------------
21
Fugue
62.32
20%
66
- C3 -
1TDP
-
CB2I_CARML
A:
[1-111]
-----------------------------------------------------------------
M
D
I
K
S
Q
T
L
Y
L
N
L
S
E
A
Y
K
D
P
E
V
K
A
N
-
E
F
L
S
K
L
V
V
--
Q
C
A
G
K
L
T
A
S
N
S
E
N
S
Y
I
E
V
I
S
L
L
S
R
G
I
S
S
Y
Y
L
S
H
K
R
I
I
P
S
S
M
L
T
I
Y
T
Q
I
Q
K
D
I
K
N
G
N
I
D
T
E
K
L
R
K
Y
E
I
A
K
G
L
M
S
V
P
Y
I
Y
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
61.98
27%
78
- C3 -
2QEJ
-
?
C:
[93-196]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
K
K
N
N
Q
S
S
E
T
N
I
H
--
L
L
V
N
K
L
D
G
G
N
L
D
A
T
N
D
-
S
---
F
L
I
N
K
E
E
V
S
L
------
K
E
L
D
F
K
I
R
K
Q
L
V
E
K
Y
G
---------
L
Y
Q
G
-----
T
S
K
Y
G
K
I
T
I
I
L
-
N
G
G
K
K
Q
E
I
D
----
L
G
D
K
L
QFE
R
M
G
D
V
L
N
S
K
D
I
N
K
I
E
V
T
L
K
Q
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
55.88
18%
73
- C3 -
4X01
4
COM1_SCHPO
A:
[6-54]
----------------------------------------------------------------------
S
V
H
W
-
S
I
V
Y
R
Q
L
G
N
L
L
E
Q
Y
E
V
E
I
A
R
L
K
S
Q
L
V
L
E
K
K
L
R
I
Q
V
E
K
E
M
E
S
V
K
T
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
54.55
16%
65
- C3 -
2BZB
-
?
A:
[1-62]
----------------------------------------------------------------------------
M
E
M
G
Q
L
K
N
K
I
E
N
K
K
K
E
L
I
Q
L
V
A
R
H
G
L
D
H
D
K
V
L
L
F
S
R
D
L
D
K
L
I
N
K
F
M
N
V
K
D
K
V
H
K
L
E
H
H
H
H
H
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
50.19
29%
-23
* C5 *
1XEE
-
CHIPS_STAAE
A:
[45-120]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
N
Y
L
K
K
G
T
K
N
S
A
Q
F
E
K
M
V
I
L
T
E
N
K
G
Y
Y
T
---
V
Y
L
N
T
P
LA
E
D
R
K
N
VELLGKMY
K
T
Y
F
F
K
K
G
E
S
K
S
S
Y
V
I
N
G
P
G
K
T
N
E
Y
A
Y
1
PsiBlast_PDB
49.34
30%
111
- C3 -
1NIO
-
RIPB_LUFAE
A:
[192-227]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
-
S
A
L
S
K
Q
-
I
Q
L
A
Q
T
N
N
G
A
F
---
R
T
P
V
V
I
I
D
N
K
G
Q
R
V
E
I
K
D
V
N
S
K
V
V
T
N
N
I
K
L
L
L
N
K
Q
N
I
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
45.22
20%
-30
- C3 -
1ZZA
-
SNN_HUMAN
A:
[19-43]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
I
L
I
A
I
A
A
L
G
-----
A
L
I
L
-
G
C
W
C
Y
L
R
L
Q
R
I
S
Q
S
E
D
E
E
S
I
V
G
D
G
E
T
K
E
P
F
L
L
--
V
Q
Y
S
A
K
G
P
C
V
E
R
K
A
K
L
-
M
T
P
N
G
P
E
V
H
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
45.09
17%
96
- C3 -
4PS2
2
?
A:
[1-79]
-------------
E
E
S
I
S
L
T
F
R
N
M
N
D
F
T
P
E
Q
V
A
R
Q
I
P
R
L
K
A
M
L
A
M
R
S
L
L
R
D
L
K
A
N
L
L
D
N
V
T
F
R
K
E
L
E
K
I
L
R
D
-------
P
A
L
S
Q
T
L
R
D
E
L
R
A
L
V
P
E
K
A
W
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
44.35
10%
95
- C3 -
4MYY
2
?
A:
[2-85]
-------------------------------------------------------------------------------
S
A
L
E
A
K
L
L
D
E
I
K
Q
S
S
N
Q
E
L
E
S
S
I
D
Q
I
L
E
S
I
I
N
G
G
S
M
L
N
K
F
T
K
K
E
Q
I
L
S
E
K
Q
Q
I
K
Q
L
S
P
L
Q
R
A
A
L
A
L
K
K
L
E
T
K
L
N
N
T
L
H
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
44.26
22%
121
- C3 -
4EC6
-
?
A:
[214-275]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Q
S
K
I
D
T
F
G
R
-
Y
F
L
T
Y
Y
F
S
Q
E
K
N
Q
-------
E
N
Y
Q
S
S
L
R
T
Y
V
S
E
K
V
D
ISDWKALGK
T
L
K
S
-----
V
N
Y
Y
G
S
E
Q
T
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
43.46
31%
124
- C3 -
2K6I
-
Y223_METJA
A:
[1-47]
----
M
G
V
S
V
M
E
A
I
K
E
V
K
L
A
E
E
Q
A
V
K
E
I
--
E
E
A
K
N
R
A
E
Q
I
K
A
E
A
I
E
E
A
K
K
L
I
A
C
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
41.86
25%
192
- C3 -
1F93
-
HNF1A_MOUSE
F:
[5-31]
---------------------------------------------------------------------------------------------
L
S
Q
L
Q
T
E
L
L
A
A
L
L
E
S
G
L
S
K
E
A
L
I
Q
A
L
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
40.88
24%
17
- C3 -
2LX0
-
?
A:
[8-28]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
I
A
G
L
V
A
L
L
-----
T
F
L
A
-
F
G
F
W
L
F
K
Y
L
Q
K
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
40.73
26%
202
* C3 *
1F93
-
HNF1A_MOUSE
H:
[5-30]
---------------------------------------------------------------------------------------------
L
S
Q
L
Q
T
E
L
L
A
A
L
L
E
S
G
L
S
K
E
A
L
I
Q
A
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
39.66
21%
-4
* C2 *
3UHM
4
LPXC_PSEAE
A:
[187-267]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
A
R
T
F
G
---
F
M
R
D
I
E
Y
L
R
S
Q
N
L
A
L
---
G
G
--
S
V
E
N
A
I
V
V
D
E
N
-
R
V
L
N
EDG
L
R
Y
E
D
E
F
V
K
H
K
I
L
D
A
I
G
D
----
L
Y
L
L
G
N
-
S
L
I
G
E
F
R
G
F
K
S
G
H
A
L
N
N
Q
L
4
PsiBlast_PDB
39.01
29%
143
* C4 *
3KM9
-
?
X:
[17-98]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
D
A
-
S
I
D
S
F
S
I
N
K
E
E
V
S
L
------
K
E
L
D
F
K
I
R
Q
H
L
V
K
N
Y
G
---------
L
Y
K
G
-----
T
T
K
Y
G
K
I
T
I
N
L
K
D
G
E
K
Q
E
-
I
D
----
L
G
D
K
L
QFE
R
M
G
D
V
L
N
S
K
D
I
N
K
I
E
V
T
L
K
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
37.49
37%
193
- C3 -
3TQ2
1
?
A:
[4-36]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
S
A
L
K
E
K
V
S
---------
A
L
K
-------
E
Q
F
L
M
L
M
F
K
V
-
S
A
L
K
E
K
-
V
S
A
L
K
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
36.15
8%
6
- C2 -
1QJO
-
A:
[18-68]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
V
M
V
K
V
G
D
K
V
---
A
A
E
Q
S
L
--
I
T
V
E
G
D
K
-
A
S
M
E
---
V
P
A
P
F
A
----------------
G
V
V
K
E
L
K
V
N
V
G
D
K
V
K
T
G
S
L
I
M
I
F
E
V
E
14
HHSearch
28.01
14%
178
- C5 -
3L1E
-
A:
[2-21]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
-
G
I
S
E
---
V
R
S
D
R
D
----------------
K
F
V
I
F
L
D
V
K
H
F
S
P
E
D
L
T
V
K
V
Q
E
D
F
V
E