@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu13770: (2016-06-21 )
MGKFEGKIALVTGGTSGIGLATAQKFVNEGAYVYITGRRQNELDKAVNQIGKNVTGVQGDISKLEDLDKLYDIIKQEKGKLDILFANAGIGNFLPLGEITEEQVDRTFDINVKGTIFTVQKALSLFPDKVGSIIVTGSTAGSIGNPAFSVYGASKAALRALVRNWILDLKGTEIRVNVVSPGGILTPAYDELFGDALEEVLENSRNTVPAGKVGTPEEVANAVSFLASDESSYLTGVELFVDGGLAQV
Atome Classification :
(34 SA)
.........10........20........30........40......---..50--.----.--......60........70........80........90........100.......110.......120.-.-.....--130.......140.-......150.......160......--.170.......180.......190..--.....--200.......210.......220.......230.......240......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MGKFE
G
K
I
A
L
V
TGGTSGI
G
L
A
T
A
Q
K
F
V
NEG
A
Y
V
Y
I
TGRRQ
N
E
L
D
K
A
V
---
N
Q
IG--K----N--VTGVQG
D
I
S
K
L
E
D
L
D
K
L
Y
D
I
I
K
QEKG
K
L
D
I
L
F
ANAGIGNFLPL
G
E
I
T
E
E
QVD
R
T
F
D
I
NV
K
G
T
I
F
T
V
Q
K
A
L
-
S
-LFPDK--V
G
S
I
I
V
TGSTAGSI-GNP
A
F
S
V
YG
A
S
K
A
A
L
R
A
L
V
R
N
W
I
LD--LKG
T
E
I
R
V
N
V
VSPGGILT
P
A
Y
D
E
L
F
G
--
D
A
L
E
E
--
V
L
E
NSRNTVPAGKVG
T
P
E
E
V
A
N
A
V
S
F
L
ASDESS
Y
L
T
G
V
E
L
F
VDGGLAQV
34
PsiBlast_CBE
84.83
55%
-101
- C1 -
4I5E
2
?
C:
[20-262]
------
K
T
A
V
I
T
G
G
N
S
G
I
G
L
A
T
A
K
R
F
V
A
E
G
A
Y
V
F
I
V
G
R
R
R
K
E
L
E
Q
A
A
---
A
E
I
G
--
R
----
N
--
V
T
A
V
K
A
D
V
T
K
L
E
D
L
D
R
L
Y
A
I
V
R
E
Q
R
G
S
I
D
V
L
F
A
N
S
G
A
I
E
Q
K
T
L
E
E
I
T
P
E
H
Y
D
R
T
F
D
V
N
V
R
G
L
I
F
T
V
Q
K
A
L
-
P
-
L
L
R
D
G
---
G
S
V
I
L
T
S
S
V
A
G
V
L
-
G
L
Q
A
H
D
T
Y
S
A
A
K
A
A
V
R
S
L
A
R
T
W
T
T
E
--
L
K
G
R
S
I
R
V
N
A
V
S
P
G
A
I
D
T
P
I
I
E
N
Q
V
S
TQ
E
E
A
D
E
--
L
R
A
K
F
A
A
A
T
P
L
G
R
V
G
R
P
E
E
L
A
A
A
V
L
F
L
A
S
D
D
S
S
Y
V
A
G
I
E
L
F
V
D
G
G
L
T
Q
V
33
PsiBlast_CBE
84.82
55%
-101
- C1 -
4I5E
1
?
D:
[20-262]
------
K
T
A
V
I
T
G
G
N
S
G
I
G
L
A
T
A
K
R
F
V
A
E
G
A
Y
V
F
I
V
G
R
R
R
K
E
L
E
Q
A
A
---
A
E
I
G
--
R
----
N
--
V
T
A
V
K
A
D
V
T
K
L
E
D
L
D
R
L
Y
A
I
V
R
E
Q
R
G
S
I
D
V
L
F
A
N
S
G
A
I
E
Q
K
T
L
E
E
I
T
P
E
H
Y
D
R
T
F
D
V
N
V
R
G
L
I
F
T
V
Q
K
A
L
-
P
-
L
L
R
D
G
---
G
S
V
I
L
T
S
S
V
A
G
V
L
-
G
L
Q
A
H
D
T
Y
S
A
A
K
A
A
V
R
S
L
A
R
T
W
T
T
E
--
L
K
G
R
S
I
R
V
N
A
V
S
P
G
A
I
D
T
P
I
I
E
N
Q
V
S
TQ
E
E
A
D
E
--
L
R
A
K
F
A
A
A
T
P
L
G
R
V
G
R
P
E
E
L
A
A
A
V
L
F
L
A
S
D
D
S
S
Y
V
A
G
I
E
L
F
V
D
G
G
L
T
Q
V
29
PsiBlast_CBE
84.18
55%
-100
- C1 -
4I5E
1
?
H:
[20-262]
------
K
T
A
V
I
T
G
G
N
S
G
I
G
L
A
T
A
K
R
F
V
A
E
G
A
Y
V
F
I
V
G
R
R
R
K
E
L
E
Q
A
A
---
A
E
I
G
--
R
----
N
--
V
T
A
V
K
A
D
V
T
K
L
E
D
L
D
R
L
Y
A
I
V
R
E
Q
R
G
S
I
D
V
L
F
A
N
S
G
A
I
E
Q
K
T
L
E
E
I
T
P
E
H
Y
D
R
T
F
D
V
N
V
R
G
L
I
F
T
V
Q
K
A
L
-
P
-
L
L
R
D
G
---
G
S
V
I
L
T
S
S
V
A
G
V
L
-
G
L
Q
A
H
D
T
Y
S
A
A
K
A
A
V
R
S
L
A
R
T
W
T
T
E
--
L
K
G
R
S
I
R
V
N
A
V
S
P
G
A
I
D
T
P
I
I
E
N
Q
V
S
TQ
E
E
A
D
E
--
L
R
A
K
F
A
A
A
T
P
L
G
R
V
G
R
P
E
E
L
A
A
A
V
L
F
L
A
S
D
D
S
S
Y
V
A
G
I
E
L
F
V
D
G
G
L
T
Q
V
30
PsiBlast_CBE
83.82
55%
-101
- C1 -
4I5E
1
?
G:
[20-262]
------
K
T
A
V
I
T
G
G
N
S
G
I
G
L
A
T
A
K
R
F
V
A
E
G
A
Y
V
F
I
V
G
R
R
R
K
E
L
E
Q
A
A
---
A
E
I
G
--
R
----
N
--
V
T
A
V
K
A
D
V
T
K
L
E
D
L
D
R
L
Y
A
I
V
R
E
Q
R
G
S
I
D
V
L
F
A
N
S
G
A
I
E
Q
K
T
L
E
E
I
T
P
E
H
Y
D
R
T
F
D
V
N
V
R
G
L
I
F
T
V
Q
K
A
L
-
P
-
L
L
R
D
G
---
G
S
V
I
L
T
S
S
V
A
G
V
L
-
G
L
Q
A
H
D
T
Y
S
A
A
K
A
A
V
R
S
L
A
R
T
W
T
T
E
--
L
K
G
R
S
I
R
V
N
A
V
S
P
G
A
I
D
T
P
I
I
E
N
Q
V
S
TQ
E
E
A
D
E
--
L
R
A
K
F
A
A
A
T
P
L
G
R
V
G
R
P
E
E
L
A
A
A
V
L
F
L
A
S
D
D
S
S
Y
V
A
G
I
E
L
F
V
D
G
G
L
T
Q
V
32
PsiBlast_CBE
83.66
55%
-102
- C1 -
4I5E
2
?
E:
[20-262]
------
K
T
A
V
I
T
G
G
N
S
G
I
G
L
A
T
A
K
R
F
V
A
E
G
A
Y
V
F
I
V
G
R
R
R
K
E
L
E
Q
A
A
---
A
E
I
G
--
R
----
N
--
V
T
A
V
K
A
D
V
T
K
L
E
D
L
D
R
L
Y
A
I
V
R
E
Q
R
G
S
I
D
V
L
F
A
N
S
G
A
I
E
Q
K
T
L
E
E
I
T
P
E
H
Y
D
R
T
F
D
V
N
V
R
G
L
I
F
T
V
Q
K
A
L
-
P
-
L
L
R
D
G
---
G
S
V
I
L
T
S
S
V
A
G
V
L
-
G
L
Q
A
H
D
T
Y
S
A
A
K
A
A
V
R
S
L
A
R
T
W
T
T
E
--
L
K
G
R
S
I
R
V
N
A
V
S
P
G
A
I
D
T
P
I
I
E
N
Q
V
S
TQ
E
E
A
D
E
--
L
R
A
K
F
A
A
A
T
P
L
G
R
V
G
R
P
E
E
L
A
A
A
V
L
F
L
A
S
D
D
S
S
Y
V
A
G
I
E
L
F
V
D
G
G
L
T
Q
V
21
PsiBlast_CBE
83.36
54%
-96
- C1 -
4BMS
1
?
K:
[2-249]
-
Y
R
L
L
N
K
T
A
V
I
T
G
G
N
S
G
I
G
L
A
T
A
K
R
F
V
A
E
G
A
Y
V
F
I
V
G
R
R
R
K
E
L
E
Q
A
A
---
A
E
I
G
--
R
----
N
--
V
T
A
V
K
A
D
V
T
K
L
E
D
L
D
R
L
Y
A
I
V
R
E
Q
R
G
S
I
D
V
L
F
A
N
S
G
A
I
E
Q
K
T
L
E
E
I
T
P
E
H
Y
D
R
T
F
D
V
N
V
R
G
L
I
F
T
V
Q
K
A
L
-
P
-
L
L
R
D
G
---
G
S
V
I
L
T
S
S
V
A
G
V
L
-
G
L
Q
A
H
D
T
Y
S
A
A
K
A
A
V
R
S
L
A
R
T
W
T
T
E
--
L
K
G
R
S
I
R
V
N
A
V
S
P
G
A
I
D
T
P
I
I
E
N
Q
V
S
TQ
E
E
A
D
E
--
L
R
A
K
F
A
A
A
T
P
L
G
R
V
G
R
P
E
E
L
A
A
A
V
L
F
L
A
S
D
D
S
S
Y
V
A
G
I
E
L
F
V
D
G
G
L
T
Q
V
4
PsiBlast_PDB
82.77
55%
-100
- C1 -
4I5E
2
?
A:
[20-262]
------
K
T
A
V
I
T
G
G
N
S
G
I
G
L
A
T
A
K
R
F
V
A
E
G
A
Y
V
F
I
V
G
R
R
R
K
E
L
E
Q
A
A
---
A
E
I
G
--
R
----
N
--
V
T
A
V
K
A
D
V
T
K
L
E
D
L
D
R
L
Y
A
I
V
R
E
Q
R
G
S
I
D
V
L
F
A
N
S
G
A
I
E
Q
K
T
L
E
E
I
T
P
E
H
Y
D
R
T
F
D
V
N
V
R
G
L
I
F
T
V
Q
K
A
L
-
P
-
L
L
R
D
G
---
G
S
V
I
L
T
S
S
V
A
G
V
L
-
G
L
Q
A
H
D
T
Y
S
A
A
K
A
A
V
R
S
L
A
R
T
W
T
T
E
--
L
K
G
R
S
I
R
V
N
A
V
S
P
G
A
I
D
T
P
I
I
E
N
Q
V
S
T
Q
E
E
A
D
E
--
L
R
A
K
F
A
A
A
T
P
L
G
R
V
G
R
P
E
E
L
A
A
A
V
L
F
L
A
S
D
D
S
S
Y
V
A
G
I
E
L
F
V
D
G
G
L
T
Q
V
31
PsiBlast_CBE
82.26
55%
-101
- C1 -
4I5E
1
?
F:
[20-262]
------
K
T
A
V
I
T
G
G
N
S
G
I
G
L
A
T
A
K
R
F
V
A
E
G
A
Y
V
F
I
V
G
R
R
R
K
E
L
E
Q
A
A
---
A
E
I
G
--
R
----
N
--
V
T
A
V
K
A
D
V
T
K
L
E
D
L
D
R
L
Y
A
I
V
R
E
Q
R
G
S
I
D
V
L
F
A
N
S
G
A
I
E
Q
K
T
L
E
E
I
T
P
E
H
Y
D
R
T
F
D
V
N
V
R
G
L
I
F
T
V
Q
K
A
L
-
P
-
L
L
R
D
G
---
G
S
V
I
L
T
S
S
V
A
G
V
L
-
G
L
Q
A
H
D
T
Y
S
A
A
K
A
A
V
R
S
L
A
R
T
W
T
T
E
--
L
K
G
R
S
I
R
V
N
A
V
S
P
G
A
I
D
T
P
I
I
E
N
Q
V
S
TQ
E
E
A
D
E
--
L
R
A
K
F
A
A
A
T
P
L
G
R
V
G
R
P
E
E
L
A
A
A
V
L
F
L
A
S
D
D
S
S
Y
V
A
G
I
E
L
F
V
D
G
G
L
T
Q
V
22
PsiBlast_CBE
81.35
54%
-96
- C1 -
4BMS
1
?
F:
[1-249]
M
Y
R
L
L
N
K
T
A
V
I
T
G
G
N
S
G
I
G
L
A
T
A
K
R
F
V
A
E
G
A
Y
V
F
I
V
G
R
R
R
K
E
L
E
Q
A
A
---
A
E
I
G
--
R
----
N
--
V
T
A
V
K
A
D
V
T
K
L
E
D
L
D
R
L
Y
A
I
V
R
E
Q
R
G
S
I
D
V
L
F
A
N
S
G
A
I
E
Q
K
T
L
E
E
I
T
P
E
H
Y
D
R
T
F
D
V
N
V
R
G
L
I
F
T
V
Q
K
A
L
-
P
-
L
L
R
D
G
---
G
S
V
I
L
T
S
S
V
A
G
V
L
-
G
L
Q
A
H
D
T
Y
S
A
A
K
A
A
V
R
S
L
A
R
T
W
T
T
E
--
L
K
G
R
S
I
R
V
N
A
V
S
P
G
A
I
D
T
P
I
I
E
N
Q
V
S
TQ
E
E
A
D
E
--
L
R
A
K
F
A
A
A
T
P
L
G
R
V
G
R
P
E
E
L
A
A
A
V
L
F
L
A
S
D
D
S
S
Y
V
A
G
I
E
L
F
V
D
G
G
L
T
Q
V
35
PsiBlast_CBE
81.21
55%
-102
- C1 -
4I5E
2
?
B:
[20-262]
------
K
T
A
V
I
T
G
G
N
S
G
I
G
L
A
T
A
K
R
F
V
A
E
G
A
Y
V
F
I
V
G
R
R
R
K
E
L
E
Q
A
A
---
A
E
I
G
--
R
----
N
--
V
T
A
V
K
A
D
V
T
K
L
E
D
L
D
R
L
Y
A
I
V
R
E
Q
R
G
S
I
D
V
L
F
A
N
S
G
A
I
E
Q
K
T
L
E
E
I
T
P
E
H
Y
D
R
T
F
D
V
N
V
R
G
L
I
F
T
V
Q
K
A
L
-
P
-
L
L
R
D
G
---
G
S
V
I
L
T
S
S
V
A
G
V
L
-
G
L
Q
A
H
D
T
Y
S
A
A
K
A
A
V
R
S
L
A
R
T
W
T
T
E
--
L
K
G
R
S
I
R
V
N
A
V
S
P
G
A
I
D
T
P
I
I
E
N
Q
V
S
TQ
E
E
A
D
E
--
L
R
A
K
F
A
A
A
T
P
L
G
R
V
G
R
P
E
E
L
A
A
A
V
L
F
L
A
S
D
D
S
S
Y
V
A
G
I
E
L
F
V
D
G
G
L
T
Q
V
23
PsiBlast_CBE
80.90
54%
-96
- C1 -
4BMS
1
?
E:
[2-249]
-
Y
R
L
L
N
K
T
A
V
I
T
G
G
N
S
G
I
G
L
A
T
A
K
R
F
V
A
E
G
A
Y
V
F
I
V
G
R
R
R
K
E
L
E
Q
A
A
---
A
E
I
G
--
R
----
N
--
V
T
A
V
K
A
D
V
T
K
L
E
D
L
D
R
L
Y
A
I
V
R
E
Q
R
G
S
I
D
V
L
F
A
N
S
G
A
I
E
Q
K
T
L
E
E
I
T
P
E
H
Y
D
R
T
F
D
V
N
V
R
G
L
I
F
T
V
Q
K
A
L
-
P
-
L
L
R
D
G
---
G
S
V
I
L
T
S
S
V
A
G
V
L
-
G
L
Q
A
H
D
T
Y
S
A
A
K
A
A
V
R
S
L
A
R
T
W
T
T
E
--
L
K
G
R
S
I
R
V
N
A
V
S
P
G
A
I
D
T
P
I
I
E
N
-
V
S
TQ
E
E
A
D
E
--
L
R
A
K
F
A
A
A
T
P
L
G
R
V
G
R
P
E
E
L
A
A
A
V
L
F
L
A
S
D
D
S
S
Y
V
A
G
I
E
L
F
V
D
G
G
L
T
Q
V
24
PsiBlast_CBE
80.69
54%
-94
- C1 -
4BMS
1
?
C:
[1-249]
M
Y
R
L
L
N
K
T
A
V
I
T
G
G
N
S
G
I
G
L
A
T
A
K
R
F
V
A
E
G
A
Y
V
F
I
V
G
R
R
R
K
E
L
E
Q
A
A
---
A
E
I
G
--
R
----
N
--
V
T
A
V
K
A
D
V
T
K
L
E
D
L
D
R
L
Y
A
I
V
R
E
Q
R
G
S
I
D
V
L
F
A
N
S
G
A
I
E
Q
K
T
L
E
E
I
T
P
E
H
Y
D
R
T
F
D
V
N
V
R
G
L
I
F
T
V
Q
K
A
L
-
P
-
L
L
R
D
G
---
G
S
V
I
L
T
S
S
V
A
G
V
L
-
G
L
Q
A
H
D
T
Y
S
A
A
K
A
A
V
R
S
L
A
R
T
W
T
T
E
--
L
K
G
R
S
I
R
V
N
A
V
S
P
G
A
I
D
T
P
I
I
E
N
Q
-
S
TQ
E
E
A
D
E
--
L
R
A
K
F
A
A
A
T
P
L
G
R
V
G
R
P
E
E
L
A
A
A
V
L
F
L
A
S
D
D
S
S
Y
V
A
G
I
E
L
F
V
D
G
G
L
T
Q
V
1
PsiBlast_PDB
78.65
57%
-95
- C1 -
4FGS
1
?
A:
[26-273]
--
R
L
N
A
K
I
A
V
I
T
G
A
T
S
G
I
G
L
A
A
A
K
R
F
V
A
E
G
A
R
V
F
I
T
G
R
R
K
D
V
L
D
A
A
I
---
A
E
I
G
--
G
----
G
--
A
V
G
I
Q
A
D
S
A
N
L
A
E
L
D
R
L
Y
E
K
V
K
A
E
A
G
R
I
D
V
L
F
V
N
A
G
G
G
S
M
L
P
L
G
E
V
T
E
E
Q
Y
D
D
T
F
D
R
N
V
K
G
V
L
F
T
V
Q
K
A
L
-
P
-
L
L
A
-
R
--
G
S
S
V
V
L
T
G
S
T
A
G
S
T
-
G
T
P
A
F
S
V
Y
A
A
S
K
A
A
L
R
S
F
A
R
N
W
I
L
D
--
L
K
D
R
G
I
R
I
N
T
L
S
P
G
P
T
E
T
----------
D
P
V
Q
Q
Q
G
L
L
N
A
L
A
A
Q
V
P
M
G
R
V
G
R
A
E
E
V
A
A
A
A
L
F
L
A
S
D
D
S
S
F
V
T
G
A
E
L
F
V
D
G
G
S
A
Q
V
25
PsiBlast_CBE
78.56
54%
-95
- C1 -
4BMS
1
?
B:
[1-249]
M
Y
R
L
L
N
K
T
A
V
I
T
G
G
N
S
G
I
G
L
A
T
A
K
R
F
V
A
E
G
A
Y
V
F
I
V
G
R
R
R
K
E
L
E
Q
A
A
---
A
E
I
G
--
R
----
N
--
V
T
A
V
K
A
D
V
T
K
L
E
D
L
D
R
L
Y
A
I
V
R
E
Q
R
G
S
I
D
V
L
F
A
N
S
G
A
I
E
Q
K
T
L
E
E
I
T
P
E
H
Y
D
R
T
F
D
V
N
V
R
G
L
I
F
T
V
Q
K
A
L
-
P
-
L
L
R
D
G
---
G
S
V
I
L
T
S
S
V
A
G
V
L
-
G
L
Q
A
H
D
T
Y
S
A
A
K
A
A
V
R
S
L
A
R
T
W
T
T
E
--
L
K
G
R
S
I
R
V
N
A
V
S
P
G
A
I
D
T
P
I
I
E
N
Q
V
-T
Q
E
E
A
D
E
--
L
R
A
K
F
A
A
A
T
P
L
G
R
V
G
R
P
E
E
L
A
A
A
V
L
F
L
A
S
D
D
S
S
Y
V
A
G
I
E
L
F
V
D
G
G
L
T
Q
V
26
PsiBlast_CBE
75.72
54%
-101
- C1 -
4BMN
3
?
D:
[5-253]
M
Y
R
L
L
N
K
T
A
V
I
T
G
G
N
S
G
I
G
L
A
T
A
K
R
F
V
A
E
G
A
Y
V
F
I
V
G
R
R
R
K
E
L
E
Q
A
A
---
A
E
I
G
--
R
----
N
--
V
T
A
V
K
A
D
V
T
K
L
E
D
L
D
R
L
Y
A
I
V
R
E
Q
R
G
S
I
D
V
L
F
A
N
S
G
A
I
E
Q
K
T
L
E
E
I
T
P
E
H
Y
D
R
T
F
D
V
N
V
R
G
L
I
F
T
V
Q
K
A
L
-
P
-
L
L
R
D
G
---
G
S
V
I
L
T
S
S
V
A
G
V
L
-
G
L
Q
A
H
D
T
Y
S
A
A
K
A
A
V
R
S
L
A
R
T
W
T
T
E
--
L
K
G
R
S
I
R
V
N
A
V
S
P
G
A
I
D
----------------------
F
A
A
A
T
P
L
G
R
V
G
R
P
E
E
L
A
A
A
V
L
F
L
A
S
D
D
S
S
Y
V
A
G
I
E
L
F
V
D
G
G
L
T
Q
V
28
PsiBlast_CBE
75.29
54%
-102
- C1 -
4BMN
3
?
B:
[5-253]
M
Y
R
L
L
N
K
T
A
V
I
T
G
G
N
S
G
I
G
L
A
T
A
K
R
F
V
A
E
G
A
Y
V
F
I
V
G
R
R
R
K
E
L
E
Q
A
A
---
A
E
I
G
--
R
----
N
--
V
T
A
V
K
A
D
V
T
K
L
E
D
L
D
R
L
Y
A
I
V
R
E
Q
R
G
S
I
D
V
L
F
A
N
S
G
A
I
E
Q
K
T
L
E
E
I
T
P
E
H
Y
D
R
T
F
D
V
N
V
R
G
L
I
F
T
V
Q
K
A
L
-
P
-
L
L
R
D
G
---
G
S
V
I
L
T
S
S
V
A
G
V
L
-
G
L
Q
A
H
D
T
Y
S
A
A
K
A
A
V
R
S
L
A
R
T
W
T
T
E
--
L
K
G
R
S
I
R
V
N
A
V
S
P
G
A
I
D
------------------------
A
A
T
P
L
G
R
V
G
R
P
E
E
L
A
A
A
V
L
F
L
A
S
D
D
S
S
Y
V
A
G
I
E
L
F
V
D
G
G
L
T
Q
V
27
PsiBlast_CBE
73.89
54%
-99
- C1 -
4BMN
5
?
C:
[5-253]
M
Y
R
L
L
N
K
T
A
V
I
T
G
G
N
S
G
I
G
L
A
T
A
K
R
F
V
A
E
G
A
Y
V
F
I
V
G
R
R
R
K
E
L
E
Q
A
A
---
A
E
I
G
--
R
----
N
--
V
T
A
V
K
A
D
V
T
K
L
E
D
L
D
R
L
Y
A
I
V
R
E
Q
R
G
S
I
D
V
L
F
A
N
S
G
A
I
E
Q
K
T
L
E
E
I
T
P
E
H
Y
D
R
T
F
D
V
N
V
R
G
L
I
F
T
V
Q
K
A
L
-
P
-
L
L
R
D
G
---
G
S
V
I
L
T
S
S
V
A
G
V
L
-
G
L
Q
A
H
D
T
Y
S
A
A
K
A
A
V
R
S
L
A
R
T
W
T
T
E
--
L
K
G
R
S
I
R
V
N
A
V
S
P
G
A
I
D
---------------
E
--
L
R
A
K
F
A
A
A
T
P
L
G
R
V
G
R
P
E
E
L
A
A
A
V
L
F
L
A
S
D
D
S
S
Y
V
A
G
I
E
L
F
V
D
G
G
L
T
Q
V
2
PsiBlast_PDB
72.97
54%
-103
- C1 -
4BMN
2
?
A:
[5-253]
M
Y
R
L
L
N
K
T
A
V
I
T
G
G
N
S
G
I
G
L
A
T
A
K
R
F
V
A
E
G
A
Y
V
F
I
V
G
R
R
R
K
E
L
E
Q
A
A
---
A
E
I
G
--
R
----
N
--
V
T
A
V
K
A
D
V
T
K
L
E
D
L
D
R
L
Y
A
I
V
R
E
Q
R
G
S
I
D
V
L
F
A
N
S
G
A
I
E
Q
K
T
L
E
E
I
T
P
E
H
Y
D
R
T
F
D
V
N
V
R
G
L
I
F
T
V
Q
K
A
L
-
P
-
L
L
R
D
G
---
G
S
V
I
L
T
S
S
V
A
G
V
L
-
G
L
Q
A
H
D
T
Y
S
A
A
K
A
A
V
R
S
L
A
R
T
W
T
T
E
--
L
K
G
R
S
I
R
V
N
A
V
S
P
G
A
I
D
T
P
I
----------------------
A
T
P
L
G
R
V
G
R
P
E
E
L
A
A
A
V
L
F
L
A
S
D
D
S
S
Y
V
A
G
I
E
L
F
V
D
G
G
L
T
Q
V
41
PsiBlast_CBE
71.25
55%
-98
- C1 -
4I5D
1
?
B:
[20-262]
------
K
T
A
V
I
T
G
G
N
S
G
I
G
L
A
T
A
K
R
F
V
A
E
G
A
Y
V
F
I
V
G
R
R
R
K
E
L
E
Q
A
A
---
A
E
I
G
--
R
----
N
--
V
T
A
V
K
A
D
V
T
K
L
E
D
L
D
R
L
Y
A
I
V
R
E
Q
R
G
S
I
D
V
L
F
A
N
S
G
A
I
E
Q
K
T
L
E
E
I
T
P
E
H
Y
D
R
T
F
D
V
N
V
R
G
L
I
F
T
V
Q
K
A
L
-
P
-
L
L
R
D
G
---
G
S
V
I
L
T
S
S
V
A
G
V
L
-
G
L
Q
A
H
D
T
Y
S
A
A
K
A
A
V
R
S
L
A
R
T
W
T
T
E
--
L
K
G
R
S
I
R
V
N
A
V
S
P
G
A
I
D
T
P
------------------
A
K
F
A
A
A
T
P
L
G
R
V
G
R
P
E
E
L
A
A
A
V
L
F
L
A
S
D
D
S
S
Y
V
A
G
I
E
L
F
V
D
G
G
L
T
Q
V
36
PsiBlast_CBE
70.17
55%
-97
- C1 -
4I5D
1
?
G:
[20-262]
------
K
T
A
V
I
T
G
G
N
S
G
I
G
L
A
T
A
K
R
F
V
A
E
G
A
Y
V
F
I
V
G
R
R
R
K
E
L
E
Q
A
A
---
A
E
I
G
--
R
----
N
--
V
T
A
V
K
A
D
V
T
K
L
E
D
L
D
R
L
Y
A
I
V
R
E
Q
R
G
S
I
D
V
L
F
A
N
S
G
A
I
E
Q
K
T
L
E
E
I
T
P
E
H
Y
D
R
T
F
D
V
N
V
R
G
L
I
F
T
V
Q
K
A
L
-
P
-
L
L
R
D
G
---
G
S
V
I
L
T
S
S
V
A
G
V
L
-
G
L
Q
A
H
D
T
Y
S
A
A
K
A
A
V
R
S
L
A
R
T
W
T
T
E
--
L
K
G
R
S
I
R
V
N
A
V
S
P
G
A
I
D
T
P
------------------
A
K
F
A
A
A
T
P
L
G
R
V
G
R
P
E
E
L
A
A
A
V
L
F
L
A
S
D
D
S
S
Y
V
A
G
I
E
L
F
V
D
G
G
L
T
Q
V
43
PsiBlast_CBE
60.61
37%
-103
- C1 -
3PK0
4
?
D:
[5-250]
M
F
D
L
Q
G
R
S
V
V
V
T
G
G
T
K
G
I
G
R
G
I
A
T
V
F
A
R
A
G
A
N
V
A
V
A
G
R
S
T
A
D
I
D
A
C
V
ADL
D
Q
L
G
--
S
G---
K
--
V
I
G
V
Q
T
D
V
S
D
R
A
Q
C
D
A
L
A
G
R
A
V
E
E
F
G
G
I
D
V
V
C
A
N
A
G
V
F
P
D
A
P
L
A
T
M
T
P
E
Q
L
N
G
I
F
A
V
N
V
N
G
T
F
Y
A
V
Q
A
C
L
D
A
-
L
I
A
S
G
--
S
G
R
V
V
L
T
S
S
I
T
G
P
I
T
G
Y
P
G
W
S
H
Y
G
A
T
K
A
A
Q
L
G
F
M
R
T
A
A
I
E
--
L
A
P
H
K
I
T
V
N
A
I
M
P
G
N
I
M
T
----
E
G
L
L
--
E
N
G
E
E
--
Y
I
A
S
M
A
R
S
I
P
A
G
A
L
G
T
P
E
D
I
G
H
L
A
A
F
L
A
T
K
E
A
G
Y
I
T
G
Q
A
I
A
V
D
G
G
----
45
PsiBlast_CBE
60.44
37%
-100
- C1 -
3PK0
5
?
B:
[5-250]
M
F
D
L
Q
G
R
S
V
V
V
T
G
G
T
K
G
I
G
R
G
I
A
T
V
F
A
R
A
G
A
N
V
A
V
A
G
R
S
T
A
D
I
D
A
C
V
A
D
L
D
Q
L
G
--
S
G
---
K
--
V
I
G
V
Q
T
D
V
S
D
R
A
Q
C
D
A
L
A
G
R
A
V
E
E
F
G
G
I
D
V
V
C
A
N
A
G
V
F
P
D
A
P
L
A
T
M
T
P
E
Q
L
N
G
I
F
A
V
N
V
N
G
T
F
Y
A
V
Q
A
C
L
D
A
-
L
I
A
S
G
--
S
G
R
V
V
L
T
S
S
I
T
G
P
I
T
G
Y
P
G
W
S
H
Y
G
A
T
K
A
A
Q
L
G
F
M
R
T
A
A
I
E
--
L
A
P
H
K
I
T
V
N
A
I
M
P
G
N
I
M
T
----
E
G
L
L
--
E
N
G
E
E
--
Y
I
A
S
M
A
R
S
I
P
A
G
A
L
G
T
P
E
D
I
G
H
L
A
A
F
L
A
T
K
E
A
G
Y
I
T
G
Q
A
I
A
V
D
G
G
----
63
PsiBlast_CBE
59.78
36%
-108
- C1 -
3RIH
10
?
A:
[36-281]
M
F
D
L
S
A
R
S
V
L
V
T
G
G
T
K
G
I
G
R
G
I
A
T
V
F
A
R
A
G
A
N
V
A
V
A
A
R
S
P
R
E
L
S
S
V
T
---
A
E
L
G
--
E
LGA
G
N
--
V
I
G
V
R
L
D
V
S
D
P
G
S
C
A
D
A
A
R
T
V
V
D
A
F
G
A
L
D
V
V
C
A
N
A
G
I
F
P
E
A
R
L
D
T
M
T
P
E
Q
L
S
E
V
L
D
V
N
V
K
G
T
V
Y
T
V
Q
A
C
L
-
A
P
L
T
A
S
G
--
R
G
R
V
I
L
T
S
S
I
T
G
P
V
T
G
Y
P
G
W
S
H
Y
G
A
S
K
A
A
Q
L
G
F
M
R
T
A
A
I
E
--
L
A
P
R
G
V
T
V
N
A
I
L
P
G
N
I
L
T
----
E
G
L
V
--
D
M
G
E
E
--
Y
I
S
G
M
A
R
S
I
P
M
G
M
L
G
S
P
V
D
I
G
H
L
A
A
F
L
A
T
D
E
A
G
Y
I
T
G
Q
A
I
V
V
D
G
G
----
48
PsiBlast_CBE
59.46
38%
-81
- C1 -
4RF2
1
?
B:
[24-268]
--
R
L
K
G
K
V
A
I
V
T
G
G
T
L
G
I
G
L
A
I
A
D
K
F
V
E
E
G
A
K
V
V
I
T
G
R
H
A
D
V
G
E
K
A
A
---
K
S
I
G
--
G
----
T
DV
I
R
F
V
Q
H
D
A
S
D
E
A
G
W
T
K
L
F
D
T
T
E
E
A
F
G
P
V
T
T
V
V
N
N
A
G
I
A
V
S
K
S
V
E
D
T
T
T
E
E
W
R
K
L
L
S
V
N
L
D
G
V
F
F
G
T
R
L
G
I
-
Q
-
R
M
K
N
K
GL
G
A
S
I
I
N
M
S
S
I
E
G
F
V
-
G
D
P
T
L
G
A
Y
N
A
S
K
G
A
V
R
I
M
S
K
S
A
A
L
D
CA
L
K
D
Y
D
V
R
V
N
T
V
H
P
G
Y
I
K
T
P
L
V
D
D
L
E
G
-----
A
E
--
E
M
M
S
Q
R
T
K
T
P
M
G
H
I
G
E
P
N
D
I
A
W
I
C
V
Y
L
A
S
D
E
S
K
F
A
T
G
A
E
F
V
V
D
G
G
----
7
PsiBlast_PDB
59.27
37%
-100
- C1 -
3PK0
5
?
A:
[5-250]
M
F
D
L
Q
G
R
S
V
V
V
T
G
G
T
K
G
I
G
R
G
I
A
T
V
F
A
R
A
G
A
N
V
A
V
A
G
R
S
T
A
D
I
D
A
C
V
A
D
L
D
Q
L
G
--
S
G
---
K
--
V
I
G
V
Q
T
D
V
S
D
R
A
Q
C
D
A
L
A
G
R
A
V
E
E
F
G
G
I
D
V
V
C
A
N
A
G
V
F
P
D
A
P
L
A
T
M
T
P
E
Q
L
N
G
I
F
A
V
N
V
N
G
T
F
Y
A
V
Q
A
C
L
D
A
-
L
I
A
S
G
--
S
G
R
V
V
L
T
S
S
I
T
G
P
I
T
G
Y
P
G
W
S
H
Y
G
A
T
K
A
A
Q
L
G
F
M
R
T
A
A
I
E
--
L
A
P
H
K
I
T
V
N
A
I
M
P
G
N
I
M
T
----
E
G
L
L
--
E
N
G
E
E
--
Y
I
A
S
M
A
R
S
I
P
A
G
A
L
G
T
P
E
D
I
G
H
L
A
A
F
L
A
T
K
E
A
G
Y
I
T
G
Q
A
I
A
V
D
G
G
----
44
PsiBlast_CBE
59.19
37%
-101
- C1 -
3PK0
4
?
C:
[5-250]
M
F
D
L
Q
G
R
S
V
V
V
T
G
G
T
K
G
I
G
R
G
I
A
T
V
F
A
R
A
G
A
N
V
A
V
A
G
R
S
T
A
D
I
D
A
C
V
A
D
L
D
Q
L
G
--
S
G
---
K
--
V
I
G
V
Q
T
D
V
S
D
R
A
Q
C
D
A
L
A
G
R
A
V
E
E
F
G
G
I
D
V
V
C
A
N
A
G
V
F
P
D
A
P
L
A
T
M
T
P
E
Q
L
N
G
I
F
A
V
N
V
N
G
T
F
Y
A
V
Q
A
C
L
D
A
-
L
I
A
S
G
--
S
G
R
V
V
L
T
S
S
I
T
G
P
I
T
G
Y
P
G
W
S
H
Y
G
A
T
K
A
A
Q
L
G
F
M
R
T
A
A
I
E
--
L
A
P
H
K
I
T
V
N
A
I
M
P
G
N
I
M
T
----
E
G
L
L
--
E
N
G
E
E
--
Y
I
A
S
M
A
R
S
I
P
A
G
A
L
G
T
P
E
D
I
G
H
L
A
A
F
L
A
T
K
E
A
G
Y
I
T
G
Q
A
I
A
V
D
G
G
----
17
PsiBlast_PDB
58.54
37%
-79
- C1 -
1ZJY
2
?
A:
[3-247]
--
R
L
D
G
K
V
A
I
I
T
G
G
T
L
G
I
G
L
A
I
A
T
K
F
V
E
E
G
A
K
V
M
I
T
D
R
H
S
D
V
G
E
K
A
A
---
K
S
V
G
TP
D
----
Q
--
I
Q
F
F
Q
H
D
S
S
D
E
D
G
W
T
K
L
F
D
A
T
E
K
A
F
G
P
V
S
T
L
V
N
N
A
G
I
A
V
N
K
S
V
E
E
T
T
T
A
E
W
R
K
L
L
A
V
N
L
D
G
V
F
F
G
T
R
L
G
I
-
Q
-
R
M
K
N
K
GL
G
A
S
I
I
N
M
S
S
I
E
G
F
V
-
G
D
P
S
L
G
A
Y
N
A
S
K
G
A
V
R
I
M
S
K
S
A
A
L
D
C
A
L
K
D
Y
D
V
R
V
N
T
V
H
P
G
Y
I
K
T
P
L
V
D
D
L
P
G
----
A
E
E
--
A
M
-
S
Q
R
T
K
T
P
M
G
H
I
G
E
P
N
D
I
A
Y
I
C
V
Y
L
A
S
N
E
S
K
F
A
T
G
S
E
F
V
V
D
G
G
----
20
PsiBlast_PDB
57.92
37%
-77
- C1 -
1ZK1
2
?
A:
[3-247]
--
R
L
D
G
K
V
A
I
I
T
G
G
T
L
G
I
G
L
A
I
A
T
K
F
V
E
E
G
A
K
V
M
I
T
D
R
H
S
D
V
G
E
K
A
A
---
K
S
V
G
TP
D
----
Q
--
I
Q
F
F
Q
H
D
S
S
D
E
D
G
W
T
K
L
F
D
A
T
E
K
A
F
G
P
V
S
T
L
V
N
N
A
G
I
A
V
N
K
S
V
E
E
T
T
T
A
E
W
R
K
L
L
A
V
N
L
D
G
V
F
F
G
T
R
L
G
I
-
Q
-
R
M
K
N
K
GL
G
A
S
I
I
N
M
S
S
I
E
G
F
V
-
G
D
P
S
L
G
A
Y
N
A
S
K
G
A
V
R
I
M
S
K
S
A
A
L
D
C
A
L
K
D
Y
D
V
R
V
N
T
V
H
P
G
Y
I
K
T
P
L
V
D
D
L
P
G
----
A
E
E
--
A
M
-
S
Q
R
T
K
T
P
M
G
H
I
G
E
P
N
D
I
A
Y
I
C
V
Y
L
A
S
N
E
S
K
F
A
T
G
S
E
F
V
V
D
G
G
----
11
PsiBlast_PDB
57.37
38%
-80
- C1 -
4RF2
1
?
A:
[24-268]
--
R
L
K
G
K
V
A
I
V
T
G
G
T
L
G
I
G
L
A
I
A
D
K
F
V
E
E
G
A
K
V
V
I
T
G
R
H
A
D
V
G
E
K
A
A
---
K
S
I
G
--
G
----
T
DV
I
R
F
V
Q
H
D
A
S
D
E
A
G
W
T
K
L
F
D
T
T
E
E
A
F
G
P
V
T
T
V
V
N
N
A
G
I
A
V
S
K
S
V
E
D
T
T
T
E
E
W
R
K
L
L
S
V
N
L
D
G
V
F
F
G
T
R
L
G
I
-
Q
-
R
M
K
N
K
GL
G
A
S
I
I
N
M
S
S
I
E
G
F
V
-
G
D
P
T
L
G
A
Y
N
A
S
K
G
A
V
R
I
M
S
K
S
A
A
L
D
C
A
L
K
D
Y
D
V
R
V
N
T
V
H
P
G
Y
I
K
T
P
L
V
D
D
L
E
G
-----
A
E
--
E
M
M
S
Q
R
T
K
T
P
M
G
H
I
G
E
P
N
D
I
A
W
I
C
V
Y
L
A
S
D
E
S
K
F
A
T
G
A
E
F
V
V
D
G
G
----
18
PsiBlast_PDB
57.14
37%
-79
- C1 -
1ZJZ
2
?
A:
[3-247]
--
R
L
D
G
K
V
A
I
I
T
G
G
T
L
G
I
G
L
A
I
A
T
K
F
V
E
E
G
A
K
V
M
I
T
D
R
H
S
D
V
G
E
K
A
A
---
K
S
V
G
TP
D
----
Q
--
I
Q
F
F
Q
H
D
S
S
D
E
D
G
W
T
K
L
F
D
A
T
E
K
A
F
G
P
V
S
T
L
V
N
N
A
G
I
A
V
N
K
S
V
E
E
T
T
T
A
E
W
R
K
L
L
A
V
N
L
D
G
V
F
F
G
T
R
L
G
I
-
Q
-
R
M
K
N
K
GL
G
A
S
I
I
N
M
S
S
I
E
G
F
V
-
G
D
P
S
L
G
A
Y
N
A
S
K
G
A
V
R
I
M
S
K
S
A
A
L
D
C
A
L
K
D
Y
D
V
R
V
N
T
V
H
P
G
Y
I
K
T
P
L
V
D
D
L
P
G
----
A
E
E
--
A
M
-
S
Q
R
T
K
T
P
M
G
H
I
G
E
P
N
D
I
A
Y
I
C
V
Y
L
A
S
N
E
S
K
F
A
T
G
S
E
F
V
V
D
G
G
----
61
PsiBlast_CBE
57.05
36%
-109
- C1 -
3RIH
7
?
C:
[36-281]
M
F
D
L
S
A
R
S
V
L
V
T
G
G
T
K
G
I
G
R
G
I
A
T
V
F
A
R
A
G
A
N
V
A
V
A
A
R
S
P
R
E
L
S
S
V
T
---
A
E
L
G
--
E
LGAG
N
--
V
I
G
V
R
L
D
V
S
D
P
G
S
C
A
D
A
A
R
T
V
V
D
A
F
G
A
L
D
V
V
C
A
N
A
G
I
F
P
E
A
R
L
D
T
M
T
P
E
Q
L
S
E
V
L
D
V
N
V
K
G
T
V
Y
T
V
Q
A
C
L
-
A
P
L
T
A
S
G
--
R
G
R
V
I
L
T
S
S
I
T
G
P
V
T
G
Y
P
G
W
S
H
Y
G
A
S
K
A
A
Q
L
G
F
M
R
T
A
A
I
E
--
L
A
P
R
G
V
T
V
N
A
I
L
P
G
N
I
L
T
----
E
G
L
V
--
D
M
G
E
E
--
Y
I
S
G
M
A
R
S
I
P
M
G
M
L
G
S
P
V
D
I
G
H
L
A
A
F
L
A
T
D
E
A
G
Y
I
T
G
Q
A
I
V
V
D
G
G
----
15
PsiBlast_PDB
56.78
37%
-80
- C1 -
1ZK4
2
?
A:
[3-247]
--
R
L
D
G
K
V
A
I
I
T
G
G
T
L
G
I
G
L
A
I
A
T
K
F
V
E
E
G
A
K
V
M
I
T
G
R
H
S
D
V
G
E
K
A
A
---
K
S
V
G
TP
D
----
Q
--
I
Q
F
F
Q
H
D
S
S
D
E
D
G
W
T
K
L
F
D
A
T
E
K
A
F
G
P
V
S
T
L
V
N
N
A
G
I
A
V
N
K
S
V
E
E
T
T
T
A
E
W
R
K
L
L
A
V
N
L
D
G
V
F
F
G
T
R
L
G
I
-
Q
-
R
M
K
N
K
GL
G
A
S
I
I
N
M
S
S
I
E
G
F
V
-
G
D
P
S
L
G
A
Y
N
A
S
K
G
A
V
R
I
M
S
K
S
A
A
L
D
C
A
L
K
D
Y
D
V
R
V
N
T
V
H
P
G
Y
I
K
T
P
L
V
D
D
L
P
G
----
A
E
E
--
A
M
-
S
Q
R
T
K
T
P
M
G
H
I
G
E
P
N
D
I
A
Y
I
C
V
Y
L
A
S
N
E
S
K
F
A
T
G
S
E
F
V
V
D
G
G
----
19
PsiBlast_PDB
56.75
37%
-77
- C1 -
1ZK0
2
?
A:
[3-247]
--
R
L
D
G
K
V
A
I
I
T
G
G
T
L
G
I
G
L
A
I
A
T
K
F
V
E
E
G
A
K
V
M
I
T
D
R
H
S
D
V
G
E
K
A
A
---
K
S
V
G
TP
D
----
Q
--
I
Q
F
F
Q
H
D
S
S
D
E
D
G
W
T
K
L
F
D
A
T
E
K
A
F
G
P
V
S
T
L
V
N
N
A
G
I
A
V
N
K
S
V
E
E
T
T
T
A
E
W
R
K
L
L
A
V
N
L
D
G
V
F
F
G
T
R
L
G
I
-
Q
-
R
M
K
N
K
GL
G
A
S
I
I
N
M
S
S
I
E
G
F
V
-
G
D
P
S
L
G
A
Y
N
A
S
K
G
A
V
R
I
M
S
K
S
A
A
L
D
C
A
L
K
D
Y
D
V
R
V
N
T
V
H
P
G
Y
I
K
T
P
L
V
D
D
L
P
G
----
A
E
E
--
A
M
-
S
Q
R
T
K
T
P
M
G
H
I
G
E
P
N
D
I
A
Y
I
C
V
Y
L
A
S
N
E
S
K
F
A
T
G
S
E
F
V
V
D
G
G
----
62
PsiBlast_CBE
54.42
36%
-108
- C1 -
3RIH
11
?
B:
[36-281]
M
F
D
L
S
A
R
S
V
L
V
T
G
G
T
K
G
I
G
R
G
I
A
T
V
F
A
R
A
G
A
N
V
A
V
A
A
R
S
P
R
E
L
S
S
V
T
---
A
E
L
G
--
E
LGAG
N
--
V
I
G
V
R
L
D
V
S
D
P
G
S
C
A
D
A
A
R
T
V
V
D
A
F
G
A
L
D
V
V
C
A
N
A
G
I
F
P
E
A
R
L
D
T
M
T
P
E
Q
L
S
E
V
L
D
V
N
V
K
G
T
V
Y
T
V
Q
A
C
L
-
A
P
L
T
A
S
G
--
R
G
R
V
I
L
T
S
S
I
T
G
P
V
T
G
Y
P
G
W
S
H
Y
G
A
S
K
A
A
Q
L
G
F
M
R
T
A
A
I
E
--
L
A
P
R
G
V
T
V
N
A
I
L
P
G
N
I
L
T
----
E
G
L
V
--
D
M
G
E
E
--
Y
I
S
G
M
A
R
S
I
P
M
G
M
L
G
S
P
V
D
I
G
H
L
A
A
F
L
A
T
D
E
A
G
Y
I
T
G
Q
A
I
V
V
D
G
G
----