@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu15910: (2016-06-25 )
MLNDKTAIVTGASRGIGRSIALDLAKSGANVVVNYSGNEAKANEVVDEIKSMGRKAIAVKADVSNPEDVQNMIKETLSVFSTIDILVNNAGITRDNLIMRMKEDEWDDVININLKGVFNCTKAVTRQMMKQRSGRIINVSSIVGVSGNPGQANYVAAKAGVIGLTKSSAKELASRNITVNAIAPGFISTDMTDKLAKDVQDEMLKQIPLARFGEPSDVSSVVTFLASEGARYMTGQTLHIDGGMVM
Atome Classification :
(44 SA)
.........10........20........30...-.....40........50-........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220....-..-.230.......240....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MLNDK
T
A
I
V
TGASRGI
G
R
S
I
A
L
D
L
A
KSGA
N
V
V
V
N
-YSGNE
A
K
A
N
E
V
V
D
E
I
K
S-MGR
K
A
I
A
V
K
ADVS
N
P
E
D
V
Q
N
M
I
K
E
T
L
S
V
F
S
T
I
D
I
L
VNNAGITR
D
N
L
I
M
RMKEDEWD
D
V
I
N
I
N
L
K
G
V
F
N
C
T
K
A
V
T
R
Q
M
M
K
Q
RSG
R
I
I
N
V
S
S
I
V
GVSGNPGQA
N
Y
V
A
AKA
G
V
IGL
T
K
S
S
A
K
E
L
A
SRN
I
T
V
N
A
IAPGFIST
D
M
T
D
K
L
A
K
D
V
Q
D
E
M
L
K
QIPLARFGE
P
S
D
V
S
S
V
V
T
F
L
A
-SE-GARYMTG
Q
T
L
HIDGGMVM
9
PsiBlast_PDB
78.46
58%
-105
- C1 -
4DML
-
?
A:
[6-248]
-
L
T
D
R
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
L
E
L
A
A
A
G
A
K
V
A
V
N
-
Y
A
S
S
A
G
A
A
D
E
V
V
A
A
I
A
A
-
A
G
G
E
A
F
A
V
K
A
D
V
S
Q
E
S
E
V
E
A
L
F
A
A
V
I
E
R
W
G
R
L
D
V
L
V
N
N
A
G
I
T
R
D
T
L
L
L
R
M
K
R
D
D
W
Q
S
V
L
D
L
N
L
G
G
V
F
L
C
S
R
A
A
A
K
I
M
L
K
Q
R
S
G
R
I
I
N
I
A
S
V
V
G
E
M
G
N
P
G
Q
A
N
Y
S
A
A
K
A
G
V
I
G
L
T
K
T
V
A
K
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
A
T
D
M
-----
A
---
E
K
L
L
E
V
I
P
L
G
R
Y
G
E
A
A
E
V
A
G
V
V
R
F
L
A
-
A
D
P
A
A
A
Y
I
T
G
Q
V
I
N
I
D
G
G
L
V
M
1
PsiBlast_PDB
77.90
73%
-96
- C1 -
2UVD
-
?
A:
[1-246]
M
L
K
G
K
V
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
I
D
L
A
K
Q
G
A
N
V
V
V
N
-
Y
A
G
N
E
Q
K
A
N
E
V
V
D
E
I
K
K
-
L
G
S
D
A
I
A
V
R
A
D
V
A
N
A
E
D
V
T
N
M
V
K
Q
T
V
D
V
F
G
Q
V
D
I
L
V
N
N
A
G
V
T
K
D
N
L
L
M
R
M
K
E
E
E
W
D
T
V
I
N
T
N
L
K
G
V
F
L
C
T
K
A
V
S
R
F
M
M
R
Q
R
H
G
R
I
V
N
I
A
S
V
V
G
V
T
G
N
P
G
Q
A
N
Y
V
A
A
K
A
G
V
I
G
L
T
K
T
S
A
K
E
L
A
S
R
N
I
T
V
N
A
I
A
P
G
F
I
A
T
D
M
T
D
V
L
D
E
N
I
K
A
E
M
L
K
L
I
P
A
A
Q
F
G
E
A
Q
D
I
A
N
A
V
T
F
F
A
-
S
D
-
Q
S
K
Y
I
T
G
Q
T
L
N
V
D
G
G
M
V
M
66
PsiBlast_CBE
76.21
49%
-124
- C1 -
4BO6
1
FABG_PSEAE
B:
[25-268]
-
L
Q
G
K
V
A
L
V
T
G
A
S
R
G
I
G
Q
A
I
A
L
E
L
G
R
L
G
A
-
V
V
I
G
-
T
A
T
S
A
S
G
A
E
K
I
A
E
T
L
K
A
-
N
G
V
E
G
A
G
L
V
L
D
V
S
S
D
E
S
V
A
A
T
L
E
H
I
Q
Q
H
L
G
Q
P
L
I
V
V
N
N
A
G
I
T
----------
D
E
W
F
D
V
V
N
T
N
L
N
S
L
Y
R
L
S
K
A
V
L
R
G
M
T
K
A
R
W
G
R
I
I
N
I
G
S
V
V
-----
A
G
Q
T
N
Y
A
A
A
K
A
G
L
E
G
F
T
R
A
L
A
R
E
V
G
S
R
A
I
T
V
N
A
V
A
P
G
F
I
D
T
D
M
T
R
E
L
P
E
A
Q
R
E
A
L
L
G
Q
I
P
L
G
R
L
G
Q
A
E
E
I
A
K
V
V
G
F
L
A
-
S
D
-
G
A
A
Y
V
T
G
A
T
V
P
V
N
G
G
M
Y
M
4
PsiBlast_PDB
75.48
61%
-92
- C1 -
4JRO
-
?
A:
[27-271]
-
L
Q
G
K
V
A
V
V
T
G
G
S
R
G
I
G
R
D
I
A
I
N
L
A
K
E
G
A
N
I
F
F
N
-
Y
N
G
S
P
E
A
A
E
E
T
A
K
L
V
A
E
-
H
G
V
E
V
E
A
M
K
A
N
V
A
I
A
E
D
V
D
A
F
F
K
Q
A
I
E
R
F
G
R
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
D
E
W
D
D
V
I
N
I
N
L
K
G
T
F
L
C
T
K
A
V
S
R
T
M
M
K
Q
R
A
G
K
I
I
N
M
A
S
V
V
G
L
I
G
N
A
G
Q
A
N
Y
V
A
S
K
A
G
V
I
G
L
T
K
T
T
A
R
E
L
A
P
R
G
I
N
V
N
A
V
A
P
G
F
I
T
T
D
M
T
D
K
L
D
E
K
T
K
E
A
M
L
A
Q
I
P
L
G
A
Y
G
T
T
E
D
I
A
N
A
V
L
F
L
A
-
S
D
-
A
S
K
Y
I
T
G
Q
T
L
S
V
D
G
G
M
V
M
23
PsiBlast_CBE
74.42
61%
-90
- C1 -
4JRO
1
?
C:
[27-271]
-
L
Q
G
K
V
A
V
V
T
G
G
S
R
G
I
G
R
D
I
A
I
N
L
A
K
E
G
A
N
I
F
F
N
-
Y
N
G
S
P
E
A
A
E
E
T
A
K
L
V
A
E
-
H
G
V
E
V
E
A
M
K
A
N
V
A
I
A
E
D
V
D
A
F
F
K
Q
A
I
E
R
F
G
R
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
D
E
W
D
D
V
I
N
I
N
L
K
G
T
F
L
C
T
K
A
V
S
R
T
M
M
K
Q
R
A
G
K
I
I
N
M
A
S
V
V
G
L
I
G
N
A
G
Q
A
N
Y
V
A
S
K
A
G
V
I
G
L
T
K
T
T
A
R
E
L
A
P
R
G
I
N
V
N
A
V
A
P
G
F
I
T
T
D
M
T
D
K
L
D
E
K
T
K
E
A
M
L
A
Q
I
P
L
G
A
Y
G
T
T
E
D
I
A
N
A
V
L
F
L
A
-
S
D
-
A
S
K
Y
I
T
G
Q
T
L
S
V
D
G
G
M
V
M
75
PsiBlast_CBE
74.30
49%
-123
- C1 -
4BO3
1
FABG_PSEAE
C:
[25-268]
-
L
Q
G
K
V
A
L
V
T
G
A
S
R
G
I
G
Q
A
I
A
L
E
L
G
R
L
G
A
-
V
V
I
G
-
T
A
T
S
A
S
G
A
E
K
I
A
E
T
L
K
A
-
N
G
V
E
G
A
G
L
V
L
D
V
S
S
D
E
S
V
A
A
T
L
E
H
I
Q
Q
H
L
G
Q
P
L
I
V
V
N
N
A
G
I
T
R
D
--------
D
E
W
F
D
V
V
N
T
N
L
N
S
L
Y
R
L
S
K
A
V
L
R
G
M
T
K
A
R
W
G
R
I
I
N
I
G
S
V
V
G
---
N
A
G
Q
T
N
Y
A
A
A
K
A
G
L
E
G
F
T
R
A
L
A
R
E
V
G
S
R
A
I
T
V
N
A
V
A
P
G
F
I
D
T
D
M
T
R
E
L
P
E
A
Q
R
E
A
L
L
G
Q
I
P
L
G
R
L
G
Q
A
E
E
I
A
K
V
V
G
F
L
A
-
S
D
-
G
A
A
Y
V
T
G
A
T
V
P
V
N
G
G
M
Y
M
25
PsiBlast_CBE
74.07
58%
-100
- C1 -
4DMM
1
?
D:
[26-268]
-
L
T
D
R
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
L
E
L
A
A
A
G
A
K
V
A
V
N
-
Y
A
S
S
A
G
A
A
D
E
V
V
A
A
I
A
A
-
A
G
G
E
A
F
A
V
K
A
D
V
S
Q
E
S
E
V
E
A
L
F
A
A
V
I
E
R
W
G
R
L
D
V
L
V
N
N
A
G
I
T
R
D
T
L
L
L
R
M
K
R
D
D
W
Q
S
V
L
D
L
N
L
G
G
V
F
L
C
S
R
A
A
A
K
I
M
L
K
Q
R
S
G
R
I
I
N
I
A
S
V
V
G
E
M
G
N
P
G
Q
A
N
Y
S
A
A
K
A
G
V
I
G
L
T
K
T
V
A
K
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
A
T
------------
K
L
L
E
V
I
P
L
G
R
Y
G
E
A
A
E
V
A
G
V
V
R
F
L
A
-
A
D
P
A
A
A
Y
I
T
G
Q
V
I
N
I
D
G
G
L
V
M
26
PsiBlast_CBE
73.33
58%
-103
- C1 -
4DMM
1
?
C:
[26-268]
-
L
T
D
R
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
L
E
L
A
A
A
G
A
K
V
A
V
N
-
Y
A
S
S
A
G
A
A
D
E
V
V
A
A
I
A
A
-
A
G
G
E
A
F
A
V
K
A
D
V
S
Q
E
S
E
V
E
A
L
F
A
A
V
I
E
R
W
G
R
L
D
V
L
V
N
N
A
G
I
T
R
D
T
L
L
L
R
M
K
R
D
D
W
Q
S
V
L
D
L
N
L
G
G
V
F
L
C
S
R
A
A
A
K
I
M
L
K
Q
R
S
G
R
I
I
N
I
A
S
V
V
G
E
M
G
N
P
G
Q
A
N
Y
S
A
A
K
A
G
V
I
G
L
T
K
T
V
A
K
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
A
T
D
M
---------
E
K
L
L
E
V
I
P
L
G
R
Y
G
E
A
A
E
V
A
G
V
V
R
F
L
A
-
A
D
P
A
A
A
Y
I
T
G
Q
V
I
N
I
D
G
G
L
V
M
21
PsiBlast_CBE
73.11
64%
-85
- C1 -
3SJ7
2
?
B:
[11-252]
----
K
S
A
L
V
T
G
A
S
R
G
I
G
R
S
I
A
L
Q
L
A
E
E
G
Y
N
V
A
V
N
-
Y
A
G
S
K
E
K
A
E
A
V
V
E
E
I
K
A
-
K
G
V
D
S
F
A
I
Q
A
N
V
A
D
A
D
E
V
K
A
M
I
K
E
V
V
S
Q
F
G
S
L
D
V
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
Q
E
W
D
D
V
I
D
T
N
L
K
G
V
F
N
C
I
Q
K
A
T
P
Q
M
L
R
Q
R
S
G
A
I
I
N
L
S
S
V
V
G
A
V
G
N
P
G
Q
A
N
Y
V
A
T
K
A
G
V
I
G
L
T
K
S
A
A
R
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
V
S
D
-
T
D
A
L
S
D
E
L
K
E
Q
M
L
T
Q
I
P
L
A
R
F
G
Q
D
T
D
I
A
N
T
V
A
F
L
A
-
S
D
-
K
A
K
Y
I
T
G
Q
T
I
H
V
N
G
G
M
Y
M
99
PsiBlast_CBE
73.09
49%
-114
- C1 -
4BNW
1
FABG_PSEAE
D:
[25-268]
-
L
Q
G
K
V
A
L
V
T
G
A
S
R
G
I
G
Q
A
I
A
L
E
L
G
R
L
G
A
-
V
V
I
G
-
T
A
T
S
A
S
G
A
E
K
I
A
E
T
L
K
A
-
N
G
V
E
G
A
G
L
V
L
D
V
S
S
D
E
S
V
A
A
T
L
E
H
I
Q
Q
H
L
G
Q
P
L
I
V
V
N
N
A
G
I
------
V
R
M
K
D
D
E
W
F
D
V
V
N
T
N
L
N
S
L
Y
R
L
S
K
A
V
L
R
G
M
T
K
A
R
W
G
R
I
I
N
I
G
S
V
V
G
A
M
G
N
A
G
Q
T
N
Y
A
A
A
K
A
G
L
E
G
F
T
R
A
L
A
R
E
V
G
S
R
A
I
T
V
N
A
V
A
P
G
F
I
D
T
D
M
T
R
E
L
P
E
A
Q
R
E
A
L
L
G
Q
I
P
L
G
R
L
G
Q
A
E
E
I
A
K
V
V
G
F
L
A
-
S
D
-
G
A
A
Y
V
T
G
A
T
V
P
V
N
G
G
M
Y
M
91
PsiBlast_CBE
73.06
49%
-117
- C1 -
4BNZ
1
FABG_PSEAE
A:
[25-268]
-
L
Q
G
K
V
A
L
V
T
G
A
S
R
G
I
G
Q
A
I
A
L
E
L
G
R
L
G
A
-
V
V
I
G
-
T
A
T
S
A
S
G
A
E
K
I
A
E
T
L
K
A
-
N
G
V
E
G
A
G
L
V
L
D
V
S
S
D
E
S
V
A
A
T
L
E
H
I
Q
Q
H
L
G
Q
P
L
I
V
V
N
N
A
G
--------
R
M
K
D
D
E
W
F
D
V
V
N
T
N
L
N
S
L
Y
R
L
S
K
A
V
L
R
G
M
T
K
A
R
W
G
R
I
I
N
I
G
S
V
V
G
A
M
G
N
A
G
Q
T
N
Y
A
A
A
K
A
G
L
E
G
F
T
R
A
L
A
R
E
V
G
S
R
A
I
T
V
N
A
V
A
P
G
F
I
D
T
D
M
T
R
E
L
P
E
A
Q
R
E
A
L
L
G
Q
I
P
L
G
R
L
G
Q
A
E
E
I
A
K
V
V
G
F
L
A
-
S
D
-
G
A
A
Y
V
T
G
A
T
V
P
V
N
G
G
M
Y
M
5
PsiBlast_PDB
72.97
58%
-103
- C1 -
4RZH
-
FABG1_SYNY3
A:
[4-246]
-
L
T
A
Q
V
A
L
V
T
G
A
S
R
G
I
G
K
A
T
A
L
A
L
A
A
T
G
M
K
V
V
V
N
-
Y
A
Q
S
S
T
A
A
D
A
V
V
A
E
I
I
A
-
N
G
G
E
A
I
A
V
Q
A
N
V
A
N
A
D
E
V
D
Q
L
I
K
T
T
L
D
K
F
S
R
I
D
V
L
V
N
N
A
G
I
T
R
D
T
L
L
L
R
M
K
L
E
D
W
Q
A
V
I
D
L
N
L
T
G
V
F
L
C
T
K
A
V
S
K
L
M
L
K
Q
K
S
G
R
I
I
N
I
T
S
V
A
G
M
M
G
N
P
G
Q
A
N
Y
S
A
A
K
A
G
V
I
G
F
T
K
T
V
A
K
E
L
A
S
R
G
V
T
V
N
A
V
A
P
G
F
I
A
-------------
P
I
L
Q
F
I
P
L
A
R
Y
G
Q
P
E
E
V
A
G
T
I
R
F
L
A
-
T
D
P
A
A
A
Y
I
T
G
Q
T
F
N
V
D
G
G
M
V
M
90
PsiBlast_CBE
72.84
49%
-120
- C1 -
4BNZ
1
FABG_PSEAE
B:
[25-268]
-
L
Q
G
K
V
A
L
V
T
G
A
S
R
G
I
G
Q
A
I
A
L
E
L
G
R
L
G
A
-
V
V
I
G
-
T
A
T
S
A
S
G
A
E
K
I
A
E
T
L
K
A
-
N
G
V
E
G
A
G
L
V
L
D
V
S
S
D
E
S
V
A
A
T
L
E
H
I
Q
Q
H
L
G
Q
P
L
I
V
V
N
N
A
G
I
T
R
D
--------
D
E
W
F
D
V
V
N
T
N
L
N
S
L
Y
R
L
S
K
A
V
L
R
G
M
T
K
A
R
W
G
R
I
I
N
I
G
S
V
V
-----
A
G
Q
T
N
Y
A
A
A
K
A
G
L
E
G
F
T
R
A
L
A
R
E
V
G
S
R
A
I
T
V
N
A
V
A
P
G
F
I
D
T
D
M
T
R
E
L
P
E
A
Q
R
E
A
L
L
G
Q
I
P
L
G
R
L
G
Q
A
E
E
I
A
K
V
V
G
F
L
A
-
S
D
-
G
A
A
Y
V
T
G
A
T
V
P
V
N
G
G
M
Y
M
78
PsiBlast_CBE
72.65
49%
-115
- C1 -
4BO2
1
FABG_PSEAE
D:
[25-268]
-
L
Q
G
K
V
A
L
V
T
G
A
S
R
G
I
G
Q
A
I
A
L
E
L
G
R
L
G
A
-
V
V
I
G
-
T
A
T
S
A
S
G
A
E
K
I
A
E
T
L
K
A
-
N
G
V
E
G
A
G
L
V
L
D
V
S
S
D
E
S
V
A
A
T
L
E
H
I
Q
Q
H
L
G
Q
P
L
I
V
V
N
N
A
G
I
-------
R
M
K
D
D
E
W
F
D
V
V
N
T
N
L
N
S
L
Y
R
L
S
K
A
V
L
R
G
M
T
K
A
R
W
G
R
I
I
N
I
G
S
V
V
G
A
M
G
N
A
G
Q
T
N
Y
A
A
A
K
A
G
L
E
G
F
T
R
A
L
A
R
E
V
G
S
R
A
I
T
V
N
A
V
A
P
G
F
I
D
T
D
M
T
R
E
L
P
E
A
Q
R
E
A
L
L
G
Q
I
P
L
G
R
L
G
Q
A
E
E
I
A
K
V
V
G
F
L
A
-
S
D
-
G
A
A
Y
V
T
G
A
T
V
P
V
N
G
G
M
Y
M
58
PsiBlast_CBE
72.57
49%
-123
- C1 -
4BO8
2
FABG_PSEAE
C:
[25-268]
-
L
Q
G
K
V
A
L
V
T
G
A
S
R
G
I
G
Q
A
I
A
L
E
L
G
R
L
G
A
-
V
V
I
G
-
T
A
T
S
A
S
G
A
E
K
I
A
E
T
L
K
A
-
N
G
V
E
G
A
G
L
V
L
D
V
S
S
D
E
S
V
A
A
T
L
E
H
I
Q
Q
H
L
G
Q
P
L
I
V
V
N
N
A
G
------------
D
E
W
F
D
V
V
N
T
N
L
N
S
L
Y
R
L
S
K
A
V
L
R
G
M
T
K
A
R
W
G
R
I
I
N
I
G
S
V
V
G
----
A
G
Q
T
N
Y
A
A
A
K
A
G
L
E
G
F
T
R
A
L
A
R
E
V
G
S
R
A
I
T
V
N
A
V
A
P
G
F
I
D
T
D
M
T
R
E
L
P
E
A
Q
R
E
A
L
L
G
Q
I
P
L
G
R
L
G
Q
A
E
E
I
A
K
V
V
G
F
L
A
-
S
D
-
G
A
A
Y
V
T
G
A
T
V
P
V
N
G
G
M
Y
M
27
PsiBlast_CBE
72.25
58%
-101
- C1 -
4DMM
1
?
B:
[26-268]
-
L
T
D
R
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
L
E
L
A
A
A
G
A
K
V
A
V
N
-
Y
A
S
S
A
G
A
A
D
E
V
V
A
A
I
A
A
-
A
G
G
E
A
F
A
V
K
A
D
V
S
Q
E
S
E
V
E
A
L
F
A
A
V
I
E
R
W
G
R
L
D
V
L
V
N
N
A
G
I
T
R
D
T
L
L
L
R
M
K
R
D
D
W
Q
S
V
L
D
L
N
L
G
G
V
F
L
C
S
R
A
A
A
K
I
M
L
K
Q
R
S
G
R
I
I
N
I
A
S
V
V
G
E
M
G
N
P
G
Q
A
N
Y
S
A
A
K
A
G
V
I
G
L
T
K
T
V
A
K
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
A
T
D
M
T
S
---------
L
L
E
V
I
P
L
G
R
Y
G
E
A
A
E
V
A
G
V
V
R
F
L
A
-
A
D
P
A
A
A
Y
I
T
G
Q
V
I
N
I
D
G
G
L
V
M
83
PsiBlast_CBE
72.24
49%
-117
- C1 -
4BO1
1
FABG_PSEAE
A:
[25-268]
-
L
Q
G
K
V
A
L
V
T
G
A
S
R
G
I
G
Q
A
I
A
L
E
L
G
R
L
G
A
-
V
V
I
G
-
T
A
T
S
A
S
G
A
E
K
I
A
E
T
L
K
A
-
N
G
V
E
G
A
G
L
V
L
D
V
S
S
D
E
S
V
A
A
T
L
E
H
I
Q
Q
H
L
G
Q
P
L
I
V
V
N
N
A
G
-----------
D
D
E
W
F
D
V
V
N
T
N
L
N
S
L
Y
R
L
S
K
A
V
L
R
G
M
T
K
A
R
W
G
R
I
I
N
I
G
S
V
V
G
----
A
G
Q
T
N
Y
A
A
A
K
A
G
L
E
G
F
T
R
A
L
A
R
E
V
G
S
R
A
I
T
V
N
A
V
A
P
G
F
I
D
T
D
M
T
R
E
L
P
E
A
Q
R
E
A
L
L
G
Q
I
P
L
G
R
L
G
Q
A
E
E
I
A
K
V
V
G
F
L
A
-
S
D
-
G
A
A
Y
V
T
G
A
T
V
P
V
N
G
G
M
Y
M
63
PsiBlast_CBE
72.20
49%
-119
- C1 -
4BO7
1
FABG_PSEAE
A:
[25-268]
-
L
Q
G
K
V
A
L
V
T
G
A
S
R
G
I
G
Q
A
I
A
L
E
L
G
R
L
G
A
-
V
V
I
G
-
T
A
T
S
A
S
G
A
E
K
I
A
E
T
L
K
A
-
N
G
V
E
G
A
G
L
V
L
D
V
S
S
D
E
S
V
A
A
T
L
E
H
I
Q
Q
H
L
G
Q
P
L
I
V
V
N
N
A
-----------
K
D
D
E
W
F
D
V
V
N
T
N
L
N
S
L
Y
R
L
S
K
A
V
L
R
G
M
T
K
A
R
W
G
R
I
I
N
I
G
S
V
V
G
A
M
G
N
A
G
Q
T
N
Y
A
A
A
K
A
G
L
E
G
F
T
R
A
L
A
R
E
V
G
S
R
A
I
T
V
N
A
V
A
P
G
F
I
D
T
D
M
T
R
E
L
P
E
A
Q
R
E
A
L
L
G
Q
I
P
L
G
R
L
G
Q
A
E
E
I
A
K
V
V
G
F
L
A
-
S
D
-
G
A
A
Y
V
T
G
A
T
V
P
V
N
G
G
M
Y
M
76
PsiBlast_CBE
72.04
49%
-127
- C1 -
4BO3
2
FABG_PSEAE
B:
[25-268]
-
L
Q
G
K
V
A
L
V
T
G
A
S
R
G
I
G
Q
A
I
A
L
E
L
G
R
L
G
A
-
V
V
I
G
-
T
A
T
S
A
S
G
A
E
K
I
A
E
T
L
K
A
-
N
G
V
E
G
A
G
L
V
L
D
V
S
S
D
E
S
V
A
A
T
L
E
H
I
Q
Q
H
L
G
Q
P
L
I
V
V
N
N
A
G
-------------
E
W
F
D
V
V
N
T
N
L
N
S
L
Y
R
L
S
K
A
V
L
R
G
M
T
K
A
R
W
G
R
I
I
N
I
G
S
V
V
G
----
A
G
Q
T
N
Y
A
A
A
K
A
G
L
E
G
F
T
R
A
L
A
R
E
V
G
S
R
A
I
T
V
N
A
V
A
P
G
F
I
D
T
D
M
T
R
E
L
P
E
A
Q
R
E
A
L
L
G
Q
I
P
L
G
R
L
G
Q
A
E
E
I
A
K
V
V
G
F
L
A
-
S
D
-
G
A
A
Y
V
T
G
A
T
V
P
V
N
G
G
M
Y
M
84
PsiBlast_CBE
72.02
49%
-115
- C1 -
4BO0
1
FABG_PSEAE
D:
[25-268]
-
L
Q
G
K
V
A
L
V
T
G
A
S
R
G
I
G
Q
A
I
A
L
E
L
G
R
L
G
A
-
V
V
I
G
-
T
A
T
S
A
S
G
A
E
K
I
A
E
T
L
K
A
-
N
G
V
E
G
A
G
L
V
L
D
V
S
S
D
E
S
V
A
A
T
L
E
H
I
Q
Q
H
L
G
Q
P
L
I
V
V
N
N
A
G
I
-------
R
M
K
D
D
E
W
F
D
V
V
N
T
N
L
N
S
L
Y
R
L
S
K
A
V
L
R
G
M
T
K
A
R
W
G
R
I
I
N
I
G
S
V
V
G
A
M
G
N
A
G
Q
T
N
Y
A
A
A
K
A
G
L
E
G
F
T
R
A
L
A
R
E
V
G
S
R
A
I
T
V
N
A
V
A
P
G
F
I
D
T
D
M
T
R
E
L
P
E
A
Q
R
E
A
L
L
G
Q
I
P
L
G
R
L
G
Q
A
E
E
I
A
K
V
V
G
F
L
A
-
S
D
-
G
A
A
Y
V
T
G
A
T
V
P
V
N
G
G
M
Y
M
2
PsiBlast_PDB
71.59
64%
-81
- C1 -
3SJ7
3
?
A:
[11-252]
----
K
S
A
L
V
T
G
A
S
R
G
I
G
R
S
I
A
L
Q
L
A
E
E
G
Y
N
V
A
V
N
-
Y
A
G
S
K
E
K
A
E
A
V
V
E
E
I
K
A
-
K
G
V
D
S
F
A
I
Q
A
N
V
A
D
A
D
E
V
K
A
M
I
K
E
V
V
S
Q
F
G
S
L
D
V
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
Q
E
W
D
D
V
I
D
T
N
L
K
G
V
F
N
C
I
Q
K
A
T
P
Q
M
L
R
Q
R
S
G
A
I
I
N
L
S
S
V
V
G
A
V
G
N
P
G
Q
A
N
Y
V
A
T
K
A
G
V
I
G
L
T
K
S
A
A
R
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
V
S
D
M
T
----
D
E
L
K
E
Q
M
L
T
Q
I
P
L
A
R
F
G
Q
D
T
D
I
A
N
T
V
A
F
L
A
-
S
D
-
K
A
K
Y
I
T
G
Q
T
I
H
V
N
G
G
M
Y
M
22
PsiBlast_CBE
71.13
61%
-86
- C1 -
4JRO
1
?
D:
[27-271]
-
L
Q
G
K
V
A
V
V
T
G
G
S
R
G
I
G
R
D
I
A
I
N
L
A
K
E
G
A
N
I
F
F
N
-
Y
N
G
S
P
E
A
A
E
E
T
A
K
L
V
A
E
-
H
G
V
E
V
E
A
M
K
A
N
V
A
I
A
E
D
V
D
A
F
F
K
Q
A
I
E
R
F
G
R
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
D
E
W
D
D
V
I
N
I
N
L
K
G
T
F
L
C
T
K
A
V
S
R
T
M
M
K
Q
R
A
G
K
I
I
N
M
A
S
V
V
G
L
I
G
N
A
G
Q
A
N
Y
V
A
S
K
A
G
V
I
G
L
T
K
T
T
A
R
E
L
A
P
R
G
I
N
V
N
A
V
A
P
G
F
I
T
T
D
M
T
---
D
E
K
T
K
E
A
M
L
A
Q
I
P
L
G
A
Y
G
T
T
E
D
I
A
N
A
V
L
F
L
A
-
S
D
-
A
S
K
Y
I
T
G
Q
T
L
S
V
D
G
G
M
V
M
12
PsiBlast_PDB
70.43
53%
-105
- C1 -
4WK6
1
?
A:
[10-249]
-
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
I
-
G
-
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
G
D
-
N
G
-
K
G
M
A
L
--
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
A
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
T
K
A
L
N
D
E
Q
R
T
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
-
S
P
-
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
-
30
PsiBlast_CBE
70.08
53%
-106
- C1 -
4WK6
1
?
B:
[10-249]
-
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
I
-
G
-
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
G
D
-
N
G
-
K
G
M
A
L
--
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
A
S
V
V
G
T
M
----
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
T
K
A
L
N
D
E
Q
R
T
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
-
S
P
-
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
-
29
PsiBlast_CBE
69.94
53%
-104
- C1 -
4WK6
2
?
C:
[10-249]
-
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
I
-
G
-
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
G
D
-
N
G
-
K
G
M
A
L
--
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
A
S
V
V
G
------
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
T
K
A
L
N
D
E
Q
R
T
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
-
S
P
-
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
-
3
PsiBlast_PDB
69.79
62%
-80
- C1 -
3OSU
15
FABG_STAAM
A:
[5-243]
----
K
S
A
L
V
T
G
A
S
R
G
I
G
R
S
I
A
L
Q
L
A
E
E
G
Y
N
V
A
V
N
-
Y
A
G
S
K
E
K
A
E
A
V
V
E
E
I
K
A
-
K
G
V
D
S
F
A
I
Q
A
N
V
A
D
A
D
E
V
K
A
M
I
K
E
V
V
S
Q
F
G
S
L
D
V
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
Q
E
W
D
D
V
I
D
T
N
L
K
G
V
F
N
C
I
Q
K
A
T
P
Q
M
L
R
Q
R
S
G
A
I
I
N
L
S
S
V
V
G
A
V
G
N
P
G
Q
A
N
Y
V
A
T
K
A
G
V
I
G
L
T
K
S
A
A
R
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
V
S
D
M
T
D
A
L
S
D
E
L
K
E
Q
M
L
T
Q
I
P
L
A
R
F
G
Q
D
T
D
I
A
N
T
V
A
F
L
A
-
S
D
-
K
A
K
Y
I
T
G
Q
T
I
H
V
N
G
G
---
7
PsiBlast_PDB
68.99
54%
-94
- C1 -
1EDO
1
FABG1_BRANA
A:
[5-244]
-------
V
V
T
G
A
S
R
G
I
G
K
A
I
A
L
S
L
G
K
A
G
C
K
V
L
V
N
-
Y
A
R
S
A
K
A
A
E
E
V
S
K
Q
I
E
A
-
Y
G
G
Q
A
I
T
F
G
G
D
V
S
K
E
A
D
V
E
A
M
M
K
T
A
I
D
A
W
G
T
I
D
V
V
V
N
N
A
G
I
T
R
D
T
L
L
I
R
M
K
K
S
Q
W
D
E
V
I
D
L
N
L
T
G
V
F
L
C
T
Q
A
A
T
K
I
M
M
K
K
R
K
G
R
I
I
N
I
A
S
V
V
G
L
I
G
N
I
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
S
K
T
A
A
R
E
G
A
S
R
N
I
N
V
N
V
V
C
P
G
F
I
A
S
D
M
T
A
K
L
G
E
D
M
E
K
K
I
L
G
T
I
P
L
G
R
T
G
Q
P
E
N
V
A
G
L
V
E
F
L
A
L
S
P
-
A
A
S
Y
I
T
G
Q
A
F
T
I
D
G
G
I
A
I
35
PsiBlast_CBE
68.49
53%
-92
- C1 -
3RRO
13
FABG_VIBCH
B:
[10-250]
-
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
I
-
G
-
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
G
D
-
N
G
-
K
G
M
A
L
--
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
T
K
A
L
N
D
E
Q
R
T
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
-
S
P
-
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
47
PsiBlast_CBE
68.48
50%
-95
- C1 -
1Q7B
3
FABG_ECOLI
D:
[3-243]
-
F
E
G
K
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
E
T
L
A
A
R
G
A
K
V
I
-
G
-
T
A
T
S
E
N
G
A
Q
A
I
S
D
Y
L
G
A
-
N
G
K
---
G
L
M
L
N
V
T
D
P
A
S
I
E
S
V
L
E
K
I
R
A
E
F
G
E
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
D
E
E
W
N
D
I
I
E
T
N
L
S
S
V
F
R
L
S
K
A
V
M
R
A
M
M
K
K
R
H
G
R
I
I
T
I
G
S
V
V
G
T
M
G
N
G
G
Q
A
N
Y
A
A
A
K
A
G
L
I
G
F
S
K
S
L
A
R
E
V
A
S
R
G
I
T
V
N
V
V
A
P
G
F
I
E
T
D
M
T
R
A
L
S
D
D
Q
R
A
G
I
L
A
Q
V
P
A
G
R
L
G
G
A
Q
E
I
A
N
A
V
A
F
L
A
-
S
D
-
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
33
PsiBlast_CBE
68.23
53%
-92
- C1 -
4I08
9
FABG_VIBCH
B:
[10-250]
-
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
I
-
G
-
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
G
D
-
N
G
-
K
G
M
A
L
--
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
--
T
K
A
L
N
D
E
Q
R
T
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
-
S
P
-
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
28
PsiBlast_CBE
68.10
53%
-108
- C1 -
4WK6
2
?
D:
[10-249]
-
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
I
-
G
-
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
G
D
-
N
G
-
K
G
M
A
L
--
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
G
G
V
D
I
L
V
N
N
A
G
I
T
---
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
A
S
---------
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
T
K
A
L
N
D
E
Q
R
T
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
-
S
P
-
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
-
15
PsiBlast_PDB
68.04
53%
-90
- C1 -
3RRO
11
FABG_VIBCH
A:
[10-250]
-
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
I
-
G
-
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
G
D
-
N
G
-
K
G
M
A
L
--
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
T
K
A
L
N
D
E
Q
R
T
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
-
S
P
-
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
48
PsiBlast_CBE
67.92
50%
-95
- C1 -
1Q7B
3
FABG_ECOLI
C:
[3-243]
-
F
E
G
K
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
E
T
L
A
A
R
G
A
K
V
I
-
G
-
T
A
T
S
E
N
G
A
Q
A
I
S
D
Y
L
G
A
-
N
G
K
---
G
L
M
L
N
V
T
D
P
A
S
I
E
S
V
L
E
K
I
R
A
E
F
G
E
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
D
E
E
W
N
D
I
I
E
T
N
L
S
S
V
F
R
L
S
K
A
V
M
R
A
M
M
K
K
R
H
G
R
I
I
T
I
G
S
V
V
G
T
M
G
N
G
G
Q
A
N
Y
A
A
A
K
A
G
L
I
G
F
S
K
S
L
A
R
E
V
A
S
R
G
I
T
V
N
V
V
A
P
G
F
I
E
T
D
M
T
R
A
L
S
D
D
Q
R
A
G
I
L
A
Q
V
P
A
G
R
L
G
G
A
Q
E
I
A
N
A
V
A
F
L
A
-
S
D
-
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
14
PsiBlast_PDB
67.50
53%
-91
- C1 -
3RSH
11
FABG_VIBCH
A:
[10-250]
-
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
I
-
G
-
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
G
D
-
N
G
-
K
G
M
A
L
--
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
T
K
---
D
E
Q
R
T
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
-
S
P
-
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
24
PsiBlast_CBE
67.46
61%
-87
- C1 -
4JRO
1
?
B:
[27-271]
-
L
Q
G
K
V
A
V
V
T
G
G
S
R
G
I
G
R
D
I
A
I
N
L
A
K
E
G
A
N
I
F
F
N
-
Y
N
G
S
P
E
A
A
E
E
T
A
K
L
V
A
E
-
H
G
V
E
V
E
A
M
K
A
N
V
A
I
A
E
D
V
D
A
F
F
K
Q
A
I
E
R
F
G
R
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
D
E
W
D
D
V
I
N
I
N
L
K
G
T
F
L
C
T
K
A
V
S
R
T
M
M
K
Q
R
A
G
K
I
I
N
M
A
S
V
V
G
L
I
G
N
A
G
Q
A
N
Y
V
A
S
K
A
G
V
I
G
L
T
K
T
T
A
R
E
L
A
P
R
G
I
N
V
N
A
V
A
P
G
F
I
T
T
D
---------
K
E
A
M
L
A
Q
I
P
L
G
A
Y
G
T
T
E
D
I
A
N
A
V
L
F
L
A
-
S
D
-
A
S
K
Y
I
T
G
Q
T
L
S
V
D
G
G
M
V
M
34
PsiBlast_CBE
66.94
53%
-93
- C1 -
3RSH
12
FABG_VIBCH
B:
[10-250]
-
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
I
-
G
-
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
G
D
-
N
G
-
K
G
M
A
L
--
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
T
K
-
L
N
D
E
Q
R
T
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
-
S
P
-
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
16
PsiBlast_PDB
66.38
53%
-95
- C1 -
4I08
6
FABG_VIBCH
A:
[10-250]
-
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
I
-
G
-
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
G
D
-
N
G
-
K
G
M
A
L
--
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
----
N
D
E
Q
R
T
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
-
S
P
-
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
17
PsiBlast_PDB
66.07
53%
-110
- C1 -
3TZC
5
?
A:
[10-249]
-
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
I
-
G
-
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
G
D
-
N
G
-
K
G
M
A
L
--
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
G
G
V
D
I
L
V
N
N
A
G
I
T
R
----
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
G
S
V
V
------------
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
-----
D
E
Q
R
T
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
-
S
P
-
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
-
49
PsiBlast_CBE
66.01
50%
-93
- C1 -
1Q7B
4
FABG_ECOLI
B:
[3-243]
-
F
E
G
K
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
E
T
L
A
A
R
G
A
K
V
I
-
G
-
T
A
T
S
E
N
G
A
Q
A
I
S
D
Y
L
G
A
-
N
G
K
---
G
L
M
L
N
V
T
D
P
A
S
I
E
S
V
L
E
K
I
R
A
E
F
G
E
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
D
E
E
W
N
D
I
I
E
T
N
L
S
S
V
F
R
L
S
K
A
V
M
R
A
M
M
K
K
R
H
G
R
I
I
T
I
G
S
V
V
G
T
M
G
N
G
G
Q
A
N
Y
A
A
A
K
A
G
L
I
G
F
S
K
S
L
A
R
E
V
A
S
R
G
I
T
V
N
V
V
A
P
G
F
I
E
T
D
M
T
R
--
S
D
D
Q
R
A
G
I
L
A
Q
V
P
A
G
R
L
G
G
A
Q
E
I
A
N
A
V
A
F
L
A
-
S
D
-
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
52
PsiBlast_CBE
65.94
50%
-92
- C1 -
1Q7C
1
FABG_ECOLI
A:
[3-243]
-
F
E
G
K
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
E
T
L
A
A
R
G
A
K
V
I
-
G
-
T
A
T
S
E
N
G
A
Q
A
I
S
D
Y
L
G
A
-
N
G
K
---
G
L
M
L
N
V
T
D
P
A
S
I
E
S
V
L
E
K
I
R
A
E
F
G
E
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
D
E
E
W
N
D
I
I
E
T
N
L
S
S
V
F
R
L
S
K
A
V
M
R
A
M
M
K
K
R
H
G
R
I
I
T
I
G
S
V
V
G
T
M
G
N
G
G
Q
A
N
F
A
A
A
K
A
G
L
I
G
F
S
K
S
L
A
R
E
V
A
S
R
G
I
T
V
N
V
V
A
P
G
F
I
E
T
D
M
T
R
A
L
S
D
D
Q
R
A
G
I
L
A
Q
V
P
A
G
R
L
G
G
A
Q
E
I
A
N
A
V
A
F
L
A
-
S
D
-
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
53
PsiBlast_CBE
64.67
50%
-97
- C1 -
2PNF
3
FABG_AQUAE
B:
[5-247]
-
L
Q
G
K
V
S
L
V
T
G
S
T
R
G
I
G
R
A
I
A
E
K
L
A
S
A
G
S
T
V
I
I
T
G
T
S
G
E
R
A
K
A
--
V
A
E
E
I
A
N
K
Y
G
V
K
A
H
G
V
E
M
N
L
L
S
E
E
S
I
N
K
A
F
E
E
I
Y
N
L
V
D
G
I
D
I
L
V
N
N
A
G
I
T
R
D
K
L
F
L
R
M
S
L
L
D
W
E
E
V
L
K
V
N
L
T
G
T
F
L
V
T
Q
N
S
L
R
K
M
I
K
Q
R
W
G
R
I
V
N
I
S
S
V
V
G
F
T
G
N
V
G
Q
V
N
Y
S
T
T
K
A
G
L
I
G
F
T
K
S
L
A
K
E
L
A
P
R
N
V
L
V
N
A
V
A
P
G
F
I
E
T
D
M
T
A
V
L
S
E
E
I
K
Q
K
Y
K
E
Q
I
P
L
G
R
F
G
S
P
E
E
V
A
N
V
V
L
F
L
C
-
S
E
-
L
A
S
Y
I
T
G
E
V
I
H
V
N
G
G
M
--
50
PsiBlast_CBE
64.52
50%
-90
- C1 -
1Q7B
4
FABG_ECOLI
A:
[3-243]
-
F
E
G
K
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
E
T
L
A
A
R
G
A
K
V
I
-
G
-
T
A
T
S
E
N
G
A
Q
A
I
S
D
Y
L
G
A
-
N
G
K
---
G
L
M
L
N
V
T
D
P
A
S
I
E
S
V
L
E
K
I
R
A
E
F
G
E
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
D
E
E
W
N
D
I
I
E
T
N
L
S
S
V
F
R
L
S
K
A
V
M
R
A
M
M
K
K
R
H
G
R
I
I
T
I
G
S
V
V
G
T
M
G
N
G
G
Q
A
N
Y
A
A
A
K
A
G
L
I
G
F
S
K
S
L
A
R
E
V
A
S
R
G
I
T
V
N
V
V
A
P
G
F
I
E
T
D
M
T
R
A
L
S
D
D
Q
R
A
G
I
L
A
Q
V
P
A
G
R
L
G
G
A
Q
E
I
A
N
A
V
A
F
L
A
-
S
D
-
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
51
PsiBlast_CBE
63.69
50%
-89
- C1 -
1Q7C
1
FABG_ECOLI
B:
[3-243]
-
F
E
G
K
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
E
T
L
A
A
R
G
A
K
V
I
-
G
-
T
A
T
S
E
N
G
A
Q
A
I
S
D
Y
L
G
A
-
N
G
K
---
G
L
M
L
N
V
T
D
P
A
S
I
E
S
V
L
E
K
I
R
A
E
F
G
E
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
D
E
E
W
N
D
I
I
E
T
N
L
S
S
V
F
R
L
S
K
A
V
M
R
A
M
M
K
K
R
H
G
R
I
I
T
I
G
S
V
V
G
T
M
G
N
G
G
Q
A
N
F
A
A
A
K
A
G
L
I
G
F
S
K
S
L
A
R
E
V
A
S
R
G
I
T
V
N
V
V
A
P
G
F
I
E
T
D
M
T
R
A
L
S
D
D
Q
R
A
G
I
L
A
Q
V
P
A
G
R
L
G
G
A
Q
E
I
A
N
A
V
A
F
L
A
-
S
D
-
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
54
PsiBlast_CBE
63.62
50%
-93
- C1 -
2PNF
3
FABG_AQUAE
A:
[5-247]
-
L
Q
G
K
V
S
L
V
T
G
S
T
R
G
I
G
R
A
I
A
E
K
L
A
S
A
G
S
T
V
I
I
T
G
T
S
G
E
R
A
K
A
--
V
A
E
E
I
A
N
K
Y
G
V
K
A
H
G
V
E
M
N
L
L
S
E
E
S
I
N
K
A
F
E
E
I
Y
N
L
V
D
G
I
D
I
L
V
N
N
A
G
I
T
R
D
K
L
F
L
R
M
S
L
L
D
W
E
E
V
L
K
V
N
L
T
G
T
F
L
V
T
Q
N
S
L
R
K
M
I
K
Q
R
W
G
R
I
V
N
I
S
S
V
V
G
F
T
G
N
V
G
Q
V
N
Y
S
T
T
K
A
G
L
I
G
F
T
K
S
L
A
K
E
L
A
P
R
N
V
L
V
N
A
V
A
P
G
F
I
E
T
D
M
T
A
V
L
S
E
E
I
K
Q
K
Y
K
E
Q
I
P
L
G
R
F
G
S
P
E
E
V
A
N
V
V
L
F
L
C
-
S
E
-
L
A
S
Y
I
T
G
E
V
I
H
V
N
G
G
M
--