@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu32040: (2016-07-23 )
MNAVVIAVLLMLVLSLLRVNIVIALIIGALAGGLTGGLGLGETVKAFTDGLGGNATVAVSYAMLGAFAAALTKTGLPDAMVEASVKLIGNKEDSRKKALSKVLIVLIILIVSCFSQNVVPVHIAFIPVLIPPLLKIFNELEMDRRLIACVITFGLTAPYILLPVGFGQIFQGMLKDNMADAGLNVPLADIPYALIIPVAGMVVGLILSVIVYRKPKQYETKDISGAEASPYTRKSIGIAVLAIVVSLGVQLYLSQTLGVEGMIMGALAGLIVLFVSGVMKRDEADSLITDGMVLMAFIGFVMLVAAGFSNVLTKTGDVESLVKTSAGFIGHSQSLGALLMLIVGLLITMGIGSSFATIPVITTIFVPLCMQLGFSPMATIAIIGAAAALGDAGSPASDSTLGPTSGLSADGQHHHIWDTCVPTFIFYNIPLVIFGWIAALVL
Atome Classification :
(20 SA)
---------.........10........---20........30..---......40........50----........60.......---------.70.....-------...-80.--.....-..90....-.-----...100.--......110---........120..--.....130--....---...140-------------------------......-----...150.......160----......----------.170..----.....180-....-..---------------...190---------.......200...-.....210-........--220-..--..-----.-.-...230....-..---.---240........250--..----------.-..------.-.----260---------.-.--------.---....-----.---270....---.-..-280--......---------------...290.......300.-.--.....310.......320...-....-.330---......----..340-------------------------------------------........350----.......360.......370.----...-...380.......390..-.....400.......410.--......420.......430.......440----------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------M
N
A
V
V
I
A
V
L
L
M
L
V
L
S
L
L
R
V
---
N
I
V
I
A
L
I
I
G
A
L
A
G
G---LTGGLG
L
G
E
T
V
K
A
F
TDGL----GGN
A
T
V
A
V
S
Y
A
M
L
G
A
F
A
---------
A
A
L
T
KTGL-------
P
D
A
-
M
V
E
--
A
S
V
K
L-IGNK
E
D
S
R
-
K
-----
K
A
L
S
K
V
L
--
I
V
L
I
I
L
I
V
----
S
C
F
SQN
V
V
P
V
H
I
A
--
F
I
P
V
L
I
P
P
--
L
L
K
I
---
F
N
E
L
---------------------------
E
M
D
R
R
L
-----
I
A
C
V
I
T
FGLTA
P
Y
I
L
L
----PV
G
F
G
Q
----------
I
F
Q
G
M
L
----
K
DNMAD---AGLN-VP---------------LADI
P
Y
---------
A
L
I
I
P
V
A
G
M
-
V
V
G
-
L
I
L
S
V
I
V
--YRKPKQYE--T---KD--IS-----G-A-EASPYT
R
K
S
I
-
G
I
---
A
---
V
-
L
A
I
V
V
S
L
G
V
Q
L
Y
--
L
S----------Q-TL------G-V----
E
G
----------
M
-
I
--------
M
---
G
A
L
A
-----
G
---
L
I
V
L
F
V
S
---
G
-
V
M-K----RD
E
A
D
S
---------------
L
I
T
D
G
M
V
L
M
A
F
I
G
F
V
M
L
-
V
--
A
A
G
F
S
N
V
LTKTG
D
V
E
S
-
L
V
K
T
-
S
A
GF-IG-H---S
Q
S
L
G
A
----
L
L
M
L
--------------------------------------------
I
V
G
L
L
I
T
MGIG----SSFA
T
I
P
V
I
T
T
I
F
V
P
L
C
M
QLG----FSP-
M
A
T
I
A
I
I
G
A
A
A
ALGDAGS-PASDSTLGPTSGLSADGQH--H
H
I
W
D
T
C
V
P
T
F
I
F
Y
N
I
P
L
V
I
F
G
W
I
A
A
L
VL----------
28
Fugue
67.72
16%
-122
- C7 -
3MK7
8
CCON1_PSEST
A:
[5-470]
TSTAYSY
K
V
V
R
Q
F
A
I
M
T
V
V
W
G
I
V
G
M
G
L
G
---
V
F
I
A
A
Q
L
A
W
P
F
L
N
F
---
D
L
P
W
T
S
F
G
R
L
R
P
L
H
T
N
A
V
I
F
A
F
G
G
C
A
L
F
A
T
S
Y
Y
S
V
Q
R
T
C
QTTLFA
P
K
L
A
A
F
T
F
W
G
W
-------
Q
L
V
-
I
L
L
--
A
A
I
S
L
-
P
L
G
F
T
S
S
K
-
E
YAELE
W
P
I
D
I
L
I
--
T
I
V
W
V
A
Y
A
----
V
V
F
F
G
T
L
A
K
R
K
V
K
--
H
I
Y
V
G
N
W
F
--
F
G
A
F
---
I
L
T
V
---------------------------
A
I
L
H
V
V
-----
N
N
L
E
I
P
V
T
A
M
K
S
Y
S
L
Y
----
A
G
A
T
D
A
----------
M
V
Q
W
W
Y
----
G
H
N
A
V
G
---
F
F
L
T
-
A
G
---------------
F
L
G
I
M
Y
---------
Y
F
V
P
K
Q
A
E
R
-
P
V
Y
-
S
-----
Y
--
R
L
S
I
V
H
F
W
--
A
---
L
I
--
T
V
-----
Y
-
I
-
W
A
G
P
H
H
L
H
Y
T
-
A
L
---
P
---
D
-
W
A
Q
S
L
G
M
V
M
S
L
I
--
L
-----------------------
L
----
A
P
----------
S
-
W
--------
G
---
G
M
I
N
-----
G
---
M
M
T
L
--
S
---
G
-
A
W
-
H
----
K
L
R
S
D
P
---------------
I
L
R
F
L
V
V
S
L
A
F
Y
G
M
S
T
F
-
E
--
G
P
M
M
A
-----
I
K
T
V
N
A
-
L
S
H
Y
-
T
D
W
T
-
I
G
-
H
V
H
-
A
G
A
L
G
W
----
V
A
M
V
--------------------------------------------
S
I
G
A
L
Y
H
L
V
P
K
VFGR
E
Q
M
H
S
I
G
L
I
N
T
H
F
--
W
L
A
T
I
G
----
T
V
L
-
Y
I
A
S
M
W
V
N
G
I
A
Q
G
L
M
W
R
A
-
I
N
D
D
G
T
L
T
Y
S
F
V
E
S
L
E
A
S
H
--
P
G
F
V
V
R
M
I
G
G
A
I
F
F
A
G
M
L
V
M
A
Y
N
T
W
R
T
V
Q
AAKPAEYDAA
12
HHSearch
66.80
13%
-126
- C7 -
4F35
2
?
D:
[40-441]
----------------
A
F
I
A
V
L
W
L
T
E
A
L
---
H
V
T
V
T
A
I
L
V
P
V
M
A
V
---
F
F
G
I
F
E
T
Q
A
A
L
N
N
F
A
N
--------
S
--
I
I
F
L
F
L
G
G
F
A
L
A
---------
A
A
M
H
H
Q
G
L
-------
D
K
V
-
I
A
D
--
K
V
L
A
M
-
A
Q
G
K
-------------
M
S
V
A
V
F
M
L
F
G
V
T
A
L
L
----
S
M
W
I
S
N
-----
T
A
--
T
A
A
M
M
L
P
L
--
V
L
G
V
---
L
S
K
V
---------------------------
D
A
D
K
Q
R
STYVF
V
L
L
G
V
A
Y
S
A
S
I
G
G
I
A
T
----
L
V
G
S
P
-------------
P
N
A
I
----
A
A
A
-------
E
V
G
-
L
S
---------------
F
T
D
W
M
K
---------
F
G
L
P
T
A
M
M
M
-
L
P
M
A
I
A
I
L
Y
F
L
--
L
------------------------------
V
N
W
D
-
K
G
K
-
V
V
---
T
---
L
-
G
I
F
G
L
T
V
F
L
W
I
F
--
S
S
----------
P
-
I
N
------
A
A
L
GGFK
S
F
----------
D
-
T
--------
L
---
V
A
L
G
-----
A
---
I
L
M
L
S
F
A
---
R
-
V
V
-
H
----
W
K
E
I
Q
K
---------------
T
A
D
W
G
V
L
------
L
L
F
G
-
G
--
G
L
C
L
S
N
V
L
K
Q
T
G
T
S
V
F
-
L
A
N
A
-
L
S
D
M
-
V
S
H
M
---
G
I
F
V
V
I
----
L
V
V
A
--------------------------------------------
T
F
V
V
F
L
T
E
F
A
-----
S
N
T
A
S
A
A
L
L
I
P
V
F
A
T
V
A
E
A
F
G
----
M
S
P
-
V
L
L
S
V
L
I
A
V
A
A
S
C
-
A
F
M
L
-
P
V
A
T
P
P
N
A
I
V
F
A
S
--
G
-
H
I
---
K
Q
S
E
-----
M
M
R
V
G
L
Y
L
N
I
A
C
I
G
L
L
T
------------
25
Fugue
66.56
20%
-78
- C7 -
4CGY
1
TOP3A_HUMAN
A:
[22-640]
---------
F
S
R
A
A
M
E
M
A
L
R
G
V
R
K
V
L
C
V
A
EK
N
D
A
A
K
G
I
A
D
L
L
S
N
G
R
M
R
R
R
E
G
L
S
K
F
N
K
I
Y
E
F
D
Y
H
L
----
Y
G
Q
N
V
T
M
V
M
T
S
V
S
G
H
L
L
---------
A
H
D
F
Q
M
Q
F
RKWQSCN
P
L
V
-
L
F
E
--
A
E
I
E
K
-
Y
C
P
E
N
F
V
D
I
K
-----
K
T
L
E
R
E
T
--
R
Q
C
Q
A
L
V
I
WTDC
D
R
E
G
E
N
I
G
F
E
I
I
H
--
V
C
K
A
V
K
P
N
--
L
Q
V
L
R
A
R
F
S
E
I
T
P
H
A
V
R
T
A
C
E
N
LTEPD
Q
R
V
S
D
A
V
D
V
R
Q
E
L
D
L
R
I
-----
G
A
A
F
T
R
F
Q
T
L
R
L
Q
R
I
F
----
P
E
V
L
A
E
QLISYG
S
C
Q
F
P
T
L
G
F
V
----
V
E
R
F
K
A
---
I
Q
A
F
-
V
P
E
I
F
H
R
I
K
V
T
H
D
H
KD
G
I
V
E
F
N
W
KRHRLFN
H
T
A
C
L
V
L
Y
Q
L
C
-
V
E
D
-
P
M
A
T
V
V
E
--
V
R
S
K
P
K
S
K
--
W
---
R
P
QA
L
D
-----
T
-
V
-
E
L
E
K
L
A
S
R
K
L
-
R
I
N
A
K
E
---
T
-
M
R
I
A
E
K
L
Y
T
Q
G
Y
--
I
S
YPRTETNIFP
R
-
D
L
------
N
-
L
----
T
V
----------
L
-
V
E
Q
Q
TPDPR
W
---
G
A
F
A
-----
Q
---
S
I
L
E
R
-
G
---
G
-
P
T
-
P
----
R
N
G
N
K
S
DQAHPPIHPTKYTNN
L
Q
G
D
E
Q
R
L
Y
E
F
I
V
R
H
F
L
-
A
--
C
C
S
Q
-
D
A
Q
G
Q
E
T
T
V
E
I
-
D
I
A
--
Q
E
R
F
-
V
A
-
H
---
G
L
M
I
L
A
----
R
N
Y
L
D
V
Y
PY
D
H
W
S
D
KILPVYEQG
S
H
F
Q
P
STVEM
V
D
G
E
T
S
P
P
KLLT
E
A
D
L
I
A
L
M
E
K
H
G
I
G
----
T
D
A
T
H
A
E
H
I
E
T
I
K
A
R
M
Y
V
G
L
T
PDK
R
F
L
P
G
H
L
G
M
G
L
V
E
G
Y
D
S
M
G
Y
E
M
S
K
P
D
L
R
A
E
L
E
A
D
L
K
L
I
C
D
G
K
K
D
K
F
V
V
L
R
Q
Q
V
Q
K
Y
K
Q
V
F
I
E
A
V
A
K
A
K
K
L
D
E
A
L
A
Q
Y
FGNGT--
14
HHSearch
66.32
16%
-118
- C7 -
4R1I
-
?
A:
[78-497]
-----------------------------------------------------
G
L
I
K
I
L
T
H
T
V
K
N
F
----
T
G
F
A
P
L
G
T
V
-
L
V
S
L
L
G
V
---------
G
I
A
E
K
S
G
L
-------
I
S
A
-
L
M
R
--
L
L
L
T
K
-
S
P
R
K
--------------
L
T
T
F
--
M
V
V
F
T
G
I
L
----
S
N
T
A
-
S
E
-----
L
--
G
Y
V
V
L
I
P
L
--
S
A
V
I
---
F
H
S
L
---------------------------
G
R
H
P
L
A
------
G
L
A
A
A
F
A
G
V
S
G
G
Y
S
A
NLFL
G
T
I
D
P
L
------------
L
A
G
I
----
T
Q
Q
A
-----
A
Q
I
I
H
P
D
---------------
Y
V
V
G
P
E
---------
A
N
W
F
F
M
A
A
S
T
F
V
I
-
A
L
I
G
Y
F
V
--
T
E
K
I
V
E
P
Q
L
G
P
Y
QS
D
L
S-
Q
E
E
K
D
I
R
H
-
S
N
E
I
T
P
L
E
-
Y
K
G
L
I
W
---
A
---
G
-
V
V
F
I
A
L
S
A
L
L
A
W
S
I
V
P
----------
A
-
D
G
IL----
R
-
H
----
P
E
TGLVAGSPFL
K
S
I
--------
V
V
F
I
F
L
L
F
-----
A
L
P
G
I
V
Y
G
R
I
T
---
R
S
L
R
-
G
----
E
R
E
V
V
N
---------------
A
M
A
E
S
M
S
T
L
G
L
Y
L
V
I
I
F
-
F
--
A
A
Q
F
V
A
F
F
N
W
T
N
I
G
Q
Y
-
I
A
V
K
-
G
A
V
F
-
L
K
-
E
VGL
A
G
S
V
L
F
----
I
G
F
I
--------------------------------------------
L
I
C
A
F
I
N
L
M
I
G
----
S
A
S
A
Q
W
A
V
T
A
P
I
F
V
P
M
L
M
L
A
G
----
Y
A
P
-
E
V
I
Q
A
A
Y
R
I
G
D
S
V
T
N
I
I
T
-
P
M
M
S
Y
F
G
L
I
M
A
T
V
M
K
Y
K
K
D
--
A
G
V
G
T
-----
L
I
S
M
M
L
P
Y
S
A
F
F
L
I
A
W
I
------------
13
HHSearch
62.56
15%
-139
- C7 -
4R0C
6
?
A:
[68-477]
--------------------------------------------------------
Y
L
F
T
T
L
V
G
N
F
----
T
G
F
A
P
L
G
-
V
V
L
V
A
M
L
G
L
---------
G
V
A
E
Q
S
G
L
-------
L
S
V
-
S
L
A
--
S
L
V
R
R
-
S
S
G
G
-------------
A
L
-
V
F
--
T
V
A
F
A
G
V
L
----
S
S
L
T
-
V
D
-----
A
--
G
Y
V
V
L
I
P
L
--
A
G
L
V
---
F
Q
L
A
---------------------------
G
R
P
P
I
A
-----
G
I
A
T
A
F
A
A
V
S
G
G
F
S
A
N
----
L
L
V
G
P
-------------
V
D
A
T
L
A
G
L
S
T
E
A
A
H
I
ID
P
D
R
T
-
V
A
---------------
A
T
G
N
Y
W
---------
F
I
I
A
S
T
F
L
V
-
T
----
G
L
V
T
L
I
T
R
T
L
T
E
P
R
L
A
--
H
A--
N
T
V
-
A
D
-----
A
S
V
-
D
A
P
Q
I
H
S
R
A
M
-
K
W
---
T
G
L
T
L
-
A
I
L
L
A
G
L
A
L
L
V
L
--
P
N
----------
D
A
P
L
RHPDTG
S
V
L
----
G
S
P
F
I
-------
H
-
G
--------
L
---
V
V
I
V
-----
A
---
L
I
A
G
I
C
G
A
V
Y
G
-
R
V
S
G
QFRN
S
G
A
V
I
T
---------------
A
M
E
V
T
M
A
S
M
A
G
Y
L
V
L
M
F
-
F
--
A
A
Q
F
V
A
W
F
N
Y
S
Q
L
G
L
L
L
A
V
K
G
-
A
A
W
L
G
A
L
T
V
---
P
K
V
V
L
L
----
L
L
F
V
--------------------------------------------
V
L
T
A
L
I
N
L
M
I
G
----
S
A
S
A
K
W
S
I
L
A
P
V
F
I
P
M
L
M
L
L
G
----
I
S
P
-
E
A
S
Q
A
A
Y
R
V
G
D
S
S
T
N
I
I
T
-
P
L
M
P
Y
F
V
L
V
L
G
F
A
R
R
Y
Q
P
E
--
T
G
I
G
T
-----
L
I
A
L
M
L
P
Y
S
L
T
L
L
L
G
W
S
------------
27
Fugue
45.77
14%
-69
- C7 -
4KK0
-
TSC1_SCHPO
A:
[2-431]
--------
P
L
Q
S
L
V
K
A
L
W
N
V
L
H
E
P
D
L
--------------------------
T
E
L
I
A
E
V
E
S
Y
Q
Q
R
Y
----
P
-
K
Q
N
P
T
N
S
Q
K
I
R
H
I
L
D
---------
E
I
Y
E
K
T
P
F
-------
N
N
------------------
T
R
R
-
R
-----
I
L
W
L
A
V
L
--
K
T
V
I
P
L
L
I
------
L
D
R
Q
A
V
G
E
W
W
D
Q
I
F
F
P
F
L
N
S
P
TQ
L
K
P
V
---
F
S
D
L
------------------------------
K
S
I
-----
L
F
Y
I
L
I
F
H
D
E
D
E
W
-------
G
G
D
L
R
R
----------
E
C
A
E
E
T
----
I
T
R
L
V
D
---
L
Y
V
S
-
K
A
---------------
I
E
N
L
E
S
---------
Q
E
Q
R
N
Q
T
I
E
-
C
L
V
-
N
V
L
V
H
Y
G
--
I
Q
R
P
K
E
L
---
S
---
S
C
--
F
C
-----
H
-
H
-
F
L
N
P
P
T
R
I
P
I
--
L
---
S
---
V
M
V
E
V
I
R
R
Q
G
P
R
L
Y
--
E
I
----------
P
-
Q
T
------
G
-
F
----
Y
D
----------
L
-
V
--------
L
---
K
C
A
E
FDTS
P
I
---
L
L
S
Y
A
L
S
---
F
-
I
L
M
I
----
L
S
H
I
C
N
---------------
S
L
D
D
S
L
Y
R
L
F
C
I
Y
L
R
F
S
M
I
DP
T
S
G
F
P
S
S
-
T
A
S
G
N
W
E
V
-
F
H
D
F
M
S
T
G
S
-
S
Q
-
P
---
D
Y
L
E
S
L
----
D
Y
S
Q
--------------------------------------------
L
F
S
I
L
Y
A
L
Y
P
I
----
N
F
L
E
F
L
R
D
P
K
L
Y
A
S
K
H
N
F
Q
I
R
----
Y
S
F
-
N
Q
E
L
L
S
T
K
S
D
G
L
L
G
R
--
H
-
L
A
H
S
N
F
L
K
Y
T
A
E
T
E
L
T
D
K
S
--
R
W
T
R
L
D
S
I
A
V
V
A
L
C
N
S
L
N
A
V
-------------------
16
HHSearch
42.05
14%
-175
- C7 -
4R1I
-
?
A:
[338-494]
----------------------------------------------------
R
G
E
R
E
V
V
N
A
M
A
E
S
M
----
S
T
L
G
L
Y
L
V
I
I
F
F
A
A
Q
F
V
---------
A
F
F
N
W
T
N
I
-------
G
Q
Y
-
I
A
V
--
K
G
A
V
F
-
L
K
E
V
G
L
----------
A
G
S
V
L
F
I
G
F
I
L
I
C
A
F
I
----
N
L
M
I
G
----
S
A
S
A
--
Q
W
A
V
T
A
P
I
--
F
V
P
M
---
L
M
L
A
---------------------------
G
Y
A
P
E
V
-----
I
Q
A
A
Y
R
I
G
D
S
V
T
N
I
I
T
----
P
M
M
S
Y
-------------
F
G
L
I
----
M
A
T
V
M
K
---
Y
K
K
D
-
A
G
---------------
V
G
T
L
I
S
---------
M
M
L
P
Y
S
A
F
F
-
L
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
41.01
25%
-179
- C6 -
3KL7
5
?
A:
[170-234]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
D
L
K
D
I
D
I
A
--
F
L
P
V
N
Q
P
Y
--
T
M
T
V
---
S
Q
A
A
---------------------------
K
A
A
R
M
F
---------------
S
P
K
I
L
Y
----
P
Y
H
Y
G
D
----------
T
K
I
G
E
L
----
K
D
A
L
K
D
---
S
G
I
D
-
V
R
---------------
I
R
E
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
38.97
12%
-150
- C7 -
4R0C
2
?
A:
[320-474]
------------------------------------------------------
S
G
A
V
I
T
A
M
E
V
T
M
----
A
S
M
A
G
Y
L
V
L
M
F
F
A
A
Q
F
V
---------
A
W
F
N
Y
S
Q
L
-------
G
L
L
L
A
V
K
--
G
A
A
W
L
G
A
L
T
V
P
------------
K
V
V
L
L
L
L
F
V
V
L
T
A
L
I
----
N
L
M
I
G
----
S
A
S
A
--
K
W
S
I
L
A
P
V
--
F
I
P
M
---
L
M
L
L
---------------------------
G
I
S
P
E
A
-----
S
Q
A
A
Y
R
V
G
D
S
S
T
N
I
I
T
----
P
L
M
P
Y
F
----------
V
--
L
V
-----
L
G
F
A
R
R
---
Y
Q
P
E
-
T
G
---------------
I
G
T
L
I
A
---------
L
M
L
P
Y
S
L
T
L
-
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
36.44
28%
-108
- C6 -
4WN3
1
PYRE_YEAST
A:
[129-210]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
----
I
D
D
V
M
T
---
A
G
T
A
-
I
N
---------------
E
A
---
F
---------
E
I
I
S
N
A
K
G
Q
-
V
V
G
----
S
I
I
A
--
L
D
R
Q
E
V
V
S
--
T
---
D
D
--
K
E
-----
G
-
L
-
S
A
T
Q
T
V
S
K
K
Y
-
G
I
---
P
---
V
-
L
S
I
V
S
L
I
H
I
I
T
Y
--
L
E
----------
G
-
R
I
------
T
-
A
----
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
36.18
28%
-107
- C6 -
4WML
1
PYRE_YEAST
A:
[128-209]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
----
I
D
D
V
M
T
---
A
G
T
A
-
I
N
---------------
E
A
---
F
---------
E
I
I
S
N
A
K
G
Q
-
V
V
G
----
S
I
I
A
--
L
D
R
Q
E
V
V
S
--
T
---
D
D
--
K
E
-----
G
-
L
-
S
A
T
Q
T
V
S
K
K
Y
-
G
I
---
P
---
V
-
L
S
I
V
S
L
I
H
I
I
T
Y
--
L
E
----------
G
-
R
I
------
T
-
A
----
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
36.17
28%
-97
- C6 -
2PS1
2
PYRE_YEAST
A:
[129-210]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
----
I
D
D
V
M
T
---
A
G
T
A
-
I
N
---------------
E
A
---
F
---------
E
I
I
S
N
A
K
G
Q
-
V
V
G
----
S
I
I
A
--
L
D
R
Q
E
V
V
S
--
T
---
D
D
--
K
E
-----
G
-
L
-
S
A
T
Q
T
V
S
K
K
Y
-
G
I
---
P
---
V
-
L
S
I
V
S
L
I
H
I
I
T
Y
--
L
E
----------
G
-
R
I
------
T
-
A
----
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
35.90
28%
-124
- C6 -
2PRY
-
PYRE_YEAST
A:
[128-209]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
----
I
D
D
V
M
T
---
A
----
I
N
---------------
E
A
---
F
---------
E
I
I
S
N
A
K
G
Q
-
V
V
G
----
S
I
I
A
--
L
D
R
Q
E
V
V
S
--
T
---
D
D
--
K
E
-----
G
-
L
-
S
A
T
Q
T
V
S
K
K
Y
-
G
I
---
P
---
V
-
L
S
I
V
S
L
I
H
I
I
T
Y
--
L
E
----------
G
-
R
I
------
T
-
A
----
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
35.58
24%
-155
- C6 -
1MHS
-
PMA1_NEUCR
A:
[245-351]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
F
A
S
---
S
-
A
V
-
K
----
R
G
E
A
------------------------------
F
V
V
I
-
T
--
A
T
G
D
N
---
T
F
V
G
R
A
A
A
-
L
V
N
A
-
A
S
G
G
-
S
G
-
H
F
--
T
E
V
L
N
G
I
G
T
I
L
L
I
L
--------------------------------------------
V
I
F
T
L
L
I
V
W
V
S
----
S
F
Y
R
S
N
P
I
V
Q
I
L
E
F
T
L
A
I
T
I
I
----
G
V
P
-
V
G
L
P
A
V
V
T
T
T
M
A
V
G
A
A
---------------------------------------------------------------
7
PsiBlast_PDB
35.16
28%
-108
- C6 -
2PRZ
1
PYRE_YEAST
A:
[129-210]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
----
I
D
D
V
M
T
---
A
G
T
A
-
I
N
---------------
E
A
---
F
---------
E
I
I
S
N
A
K
G
Q
-
V
V
G
----
S
I
I
A
--
L
D
R
Q
E
V
V
S
--
T
---
D
D
--
K
E
-----
G
-
L
-
S
A
T
Q
T
V
S
K
K
Y
-
G
I
---
P
---
V
-
L
S
I
V
S
L
I
H
I
I
T
Y
--
L
E
----------
G
-
R
I
------
T
-
A
----
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
32.51
38%
-179
- C6 -
4R1I
-
?
A:
[408-450]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
N
L
M
I
G
----
S
A
S
A
Q
W
A
V
T
A
P
I
F
V
P
M
L
M
L
A
G
----
Y
A
P
-----
E
V
I
Q
A
A
Y
R
I
G
D
S
---------------------------------------------------------------
11
PsiBlast_PDB
28.44
31%
-116
- C6 -
1M3U
1
PANB_ECOLI
A:
[122-184]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
V
Q
M
L
T
E
R
A
V
P
V
C
G
H
L
G
----
L
T
P
-
Q
-
S
V
N
I
F
G
G
Y
K
V
Q
G
-
R
G
D
-
E
A
G
D
Q
L
L
S
D
A
L
A
L
E
A
A
G
A
Q
--
L
L
V
L
E
-
C
V
P
------------------------------
4
PsiBlast_PDB
27.88
35%
-113
- C6 -
4R0C
1
?
A:
[389-432]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
L
M
I
G
----
S
A
S
A
K
W
S
I
L
A
P
V
F
I
P
M
L
M
L
L
G
----
I
S
P
-
E
A
S
----
Q
A
A
Y
R
V
G
D
S
S
T
-------------------------------------------------------------
21
Fugue
27.85
50%
14
- C4 -
3NK4
2
?
C:
[9-30]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
-
V
A
A
D
V
V
I
G
P
V
L
-
L
S
A
D
H
H
H
--
H
H
H
------------------------------------
24
Fugue
25.97
32%
-28
* C6 *
2JM6
-
APR_MOUSE
A:
[68-94]
---------------------------------------------------------------------------------------------------------------
P
A
D
-
L
K
D
E
C
A
Q
L
R
R
-
I
G
D
K
V
N
L
R
-
Q
-----
K
L
L
N
M
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------