@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0018c: (2016-04-18 )
MARVTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEVASQLVIAALAHLDDDEPGGDLLAKLDAAVRAGNSAIAAQVEMEPDLEGMGTTLTAILFAGNRLGLVHIGDSRGYLLRDGELTQITKDDTFVQTLVDEGRITPEEAHSHPQRSLIMRALTGHEVEPTLTMREARAGDRYLLCSDGLSDPVSDETILEALQIPEVAESAHRLIELALRGGGPDNVTVVVADVVDYDYGQTQPILAGAVSGDDDQLTLPNTAAGRASAISQRKEIVKRVPPQADTFSRPRWSGRRLAFVVALVTVLMTAGLLIGRAIIRSNYYVADYAGSVSIMRGIQGSLLGMSLHQPYLMGCLSPRNELSQISYGQSGGPLDCHLMKLEDLRPPERAQVRAGLPAGTLDDAIGQLRELAANSLLPPCPAPRATSPPGRPAPPTTSETTEPNVTSSPASPSPTTSAPAPTGTTPAIPTSASPAAPASPPTPWPVTSSPTMAALPPPPPQPGIDCRAAA
Atome Classification :
(20 SA)
.........10........20......-----.---.-----30---------------------------.........40--........50......-----..60....-------------.-...70........80........90----------.-........100..-..--.--.---.110--.......120.......130.......140.------......150-------.......160....-...170----........--.180........190.......200....-..-----------------.210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
A
R
V
T
L
V
L
R
Y
AARSDR
G
L
V
RANNED
S
V
-----
Y
---A-----G----------------------------
A
R
L
L
A
L
ADGMG--G
H
A
A
G
E
V
A
S
Q
L
V
I
A
A
L
-----
A
HLDDDEP-------------
G
-
G
D
L
L
A
K
L
D
A
A
V
RAGN
S
A
I
A
A
Q
V
E
M-----------E-PDLEGM
G
T
T
L
T
A
I
-
L
F--A--G---
N
R
L
G
--
L
V
H
IGDSR
G
Y
L
LRDG
E
L
T
Q
ITK
D
D
T
F
V
Q
T
L
V
------DEGRI
T
P
E
E
-------AHSH
P
Q
R
S
L
I
M
R
A
L-TGHE------VEP
T
L
T
M
R
--EA-RAGD
R
Y
L
L
CSDGLSDPVS
D
E
T
I
L
E
A
L-QI-----------------
P
E
V
A
E
S
A
H
R
L
I
E
L
A
LRGGGPD
N
V
T
V
V
V
A
D
V
VDYDYGQTQ
P
I
L
A
GAVSGDDD
Q
L
TLPNTAAG
R
A
S
A
I
S
Q
R
K
E
I
V
K
RVPPQADTFSRPRWSGR
R
L
A
F
V
V
A
L
V
T
V
L
M
T
A
G
L
L
I
G
R
A
I
I
RSN
Y
Y
V
ADYAG
S
V
S
I
M
R
G
I
Q
G
S
L
LGMSLH
Q
P
Y
L
M
G
CLSP
R
N
E
L
S
Q
ISYGQSGGPL
D
C
H
L
M
K
L
EDLRP
P
E
R
A
Q
V
RAGLPA
G
T
L
D
D
A
I
G
Q
L
R
E
L
A
A
NSLLPPCPAPRATSPPGRPAPPTTSETTEPNVTSSPASPSPTTSAPAPTGTTPAIPTSASPAAPASPPTPWPVTSSPTMAALPPPPPQPGIDCRAAA
25
HHSearch
93.98
99%
-103
- C6 -
1TXO
3
PSTP_MYCTU
A:
[3-236]
-----
L
V
L
R
Y
A
A
R
S
D
R
G
L
V
R
A
N
N
E
D
S
V
-----
Y
---
A
-----
G
----------------------------
A
R
L
L
A
L
A
D
G
M
G
--
G
H
A
A
G
E
V
A
S
Q
L
V
I
A
A
L
-----
A
H
L
D
D
D
E
P
-------------
G
-
G
D
L
L
A
K
L
D
A
A
V
R
A
G
N
S
A
I
A
A
Q
V
E
M
-----------
E
-
P
D
L
E
G
M
G
T
T
L
T
A
I
-
L
F
--
A
--
G
---
N
R
L
G
--
L
V
H
I
G
D
S
R
G
Y
L
L
R
D
G
E
L
T
Q
I
T
K
D
D
T
F
V
Q
T
L
V
------
D
E
G
R
I
T
P
E
E
-------
A
H
S
H
P
Q
R
S
L
I
M
R
A
L
-
T
G
H
E
------
V
E
P
T
L
T
M
R
--
E
A
-
R
A
G
D
R
Y
L
L
C
S
D
G
L
S
D
P
V
S
D
E
T
I
L
E
A
L
-
Q
I
-----------------
P
E
V
A
E
S
A
H
R
L
I
E
L
A
L
R
G
G
G
P
D
N
V
T
V
V
V
A
D
L
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
93.59
97%
-102
- C6 -
1TXO
3
PSTP_MYCTU
A:
[3-235]
-----
L
V
L
R
Y
A
A
R
S
D
R
G
L
V
R
A
N
N
E
D
S
V
-----
Y
---
A
-----
G
----------------------------
A
R
L
L
A
L
A
D
G
M
G
--
G
H
A
A
G
E
V
A
S
Q
L
V
I
A
A
L
-----
A
H
L
D
D
D
E
P
-------------
G
-
G
D
L
L
A
K
L
D
A
A
V
R
A
G
N
S
A
I
A
A
Q
V
E
M
-----------
E
-
P
D
L
E
G
M
G
T
T
L
T
A
I
-
L
F
--
A
--
G
---
N
R
L
G
--
L
V
H
I
G
D
S
R
G
Y
L
L
R
D
G
E
L
T
Q
I
T
K
D
D
T
F
V
Q
T
L
V
------
D
E
G
R
I
T
P
E
E
-------
A
H
S
H
P
Q
R
S
L
I
M
R
A
L
-
T
G
H
E
------
V
E
P
T
L
T
M
R
--
E
A
-
R
A
G
D
R
Y
L
L
C
S
D
G
L
S
D
P
V
S
D
E
T
I
L
E
A
L
-
Q
I
-----------------
P
E
V
A
E
S
A
H
R
L
I
E
L
A
L
R
G
G
G
P
D
N
V
T
V
V
V
A
D
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
93.27
100%
-103
- C6 -
2CM1
3
PSTP_MYCTU
A:
[25-260]
----
T
L
V
L
R
Y
A
A
R
S
D
R
G
L
V
R
A
N
N
E
D
S
V
-----
Y
---
A
-----
G
----------------------------
A
R
L
L
A
L
A
D
G
M
G
--
G
H
A
A
G
E
V
A
S
Q
L
V
I
A
A
L
-----
A
H
L
D
D
D
E
P
-------------
G
-
G
D
L
L
A
K
L
D
A
A
V
R
A
G
N
S
A
I
A
A
Q
V
E
M
-----------
E
-
P
D
L
E
G
M
G
T
T
L
T
A
I
-
L
F
--
A
--
G
---
N
R
L
G
--
L
V
H
I
G
D
S
R
G
Y
L
L
R
D
G
E
L
T
Q
I
T
K
D
D
T
F
V
Q
T
L
V
------
D
E
G
R
I
T
P
E
E
-------
A
H
------
L
I
M
R
A
L
-
T
G
H
E
------
V
E
P
T
L
T
M
R
--
E
A
-
R
A
G
D
R
Y
L
L
C
S
D
G
L
S
D
P
V
S
D
E
T
I
L
E
A
L
-
Q
I
-----------------
P
E
V
A
E
S
A
H
R
L
I
E
L
A
L
R
G
G
G
P
D
N
V
T
V
V
V
A
D
V
V
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
72.78
33%
-86
- C6 -
2PK0
2
?
A:
[2-247]
---
R
K
K
Y
M
E
I
S
L
L
T
D
I
G
Q
R
R
S
N
N
Q
D
F
I
-----
N
---
Q
F
E
N
KA
G
----------------------------
V
P
L
I
I
L
A
D
G
M
G
--
G
H
R
A
G
N
I
A
S
E
M
T
V
T
D
L
-----
G
S
D
W
A
E
T
D
FSE----------
L
-
S
E
I
R
D
W
M
L
V
S
I
E
T
E
N
R
K
I
Y
E
L
G
Q
S
-----------
D
--
D
Y
K
G
M
G
T
T
I
E
A
V
-
A
I
--
V
--
G
---
D
N
I
I
--
F
A
H
V
G
D
S
R
I
G
I
V
R
Q
G
E
Y
H
L
L
T
S
D
H
S
L
V
N
E
L
V
------
K
A
G
Q
L
T
E
E
E
-------
A
A
S
H
P
Q
K
N
I
I
T
Q
S
I
-
G
Q
A
N
P
-----
V
E
P
D
L
G
V
H
--
L
L
-
E
E
G
D
Y
L
V
V
N
S
D
G
L
T
N
M
L
S
N
A
D
I
A
T
V
L
T
Q
E
-----------------
K
T
L
D
D
K
N
Q
D
L
I
T
L
A
N
H
R
G
G
L
D
N
I
T
V
A
L
V
Y
V
E
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
71.99
38%
-79
- C6 -
2Y09
4
?
A:
[4-240]
----------
A
G
L
T
D
C
G
L
I
R
K
S
N
Q
D
A
F
-----
Y
I
DE
K
-----
H
----------------------------
Q
R
F
F
I
V
A
D
G
M
G
--
G
H
A
G
G
E
E
A
S
R
L
A
V
D
H
I
R
Q
Y
L
E
T
H
L
E
D
L
Q
H
----------------
D
P
V
T
L
L
R
Q
A
F
L
A
A
N
H
A
I
V
E
Q
Q
R
Q
-----------
N
-
S
A
R
A
D
M
G
T
T
A
V
V
I
-
L
L
D
E
K
--
G
---
D
R
A
W
--
C
A
H
V
G
A
S
R
I
Y
R
W
R
K
D
Q
L
Q
Q
I
T
S
D
H
T
W
I
A
Q
A
V
------
Q
L
G
S
L
-----------
A
R
Q
H
P
W
R
H
V
L
S
Q
C
L
--
G
R
E
------
D
L
S
Q
I
D
I
Q
P
I
D
L
-
E
P
G
D
R
L
L
L
C
S
D
G
L
T
E
E
L
T
D
D
V
I
S
I
Y
L
-
S
E
-----------------
P
N
V
Q
K
A
A
A
A
L
V
D
A
A
K
T
H
G
G
R
D
N
V
T
V
V
V
I
S
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
70.70
38%
-80
- C6 -
2XZV
4
?
A:
[4-240]
----------
A
G
L
T
D
C
G
L
I
R
K
S
N
Q
D
A
F
-----
Y
I
DE
K
-----
H
----------------------------
Q
R
F
F
I
V
A
D
G
M
G
------
G
E
E
A
S
R
L
A
V
D
H
I
R
Q
Y
L
E
T
H
L
E
D
L
Q
H
----------------
D
P
V
T
L
L
R
Q
A
F
L
A
A
N
H
A
I
V
E
Q
Q
R
Q
-----------
N
-
S
A
R
A
D
M
G
T
T
A
V
V
I
-
L
L
D
E
K
--
G
---
D
R
A
W
--
C
A
H
V
G
D
S
R
I
Y
R
W
R
K
D
Q
L
Q
Q
I
T
S
D
H
T
W
I
A
Q
A
V
------
Q
L
G
S
L
T
I
E
Q
-------
A
R
Q
H
P
W
R
H
V
L
S
Q
C
L
--
G
R
E
------
D
L
S
Q
I
D
I
Q
P
I
D
L
-
E
P
G
D
R
L
L
L
C
S
A
G
L
T
E
E
L
T
D
D
V
I
S
I
Y
L
-
S
E
-----------------
P
N
V
Q
K
A
A
A
A
L
V
D
A
A
K
T
H
G
G
R
D
N
V
T
V
V
V
I
S
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
69.47
21%
-79
- C6 -
3QN1
3
P2C16_ARATH
B:
[13-331]
------
I
P
L
W
G
T
V
S
I
Q
G
N
-
R
S
E
M
E
D
A
F
-----
A
---
V
-----
S
P
HFLKLPIKMLMT
H
L
T
------------
G
H
F
F
G
V
Y
D
G
H
G
--
G
H
K
V
A
D
Y
C
R
D
R
L
H
F
A
L
-----
A
E
E
I
E
R
I
K
--------------Q
V
Q
W
D
K
V
F
T
S
C
F
L
T
V
D
G
E
I
E
G
K
I
G
R
AVVGSSDKVLE
A
-
V
A
S
E
T
V
G
S
T
A
V
V
A
-
L
V
--
C
--
S
---
S
H
I
V
--
V
S
N
C
G
D
S
R
A
V
L
F
R
G
K
E
A
M
P
L
S
V
D
H
K
P
D
R
E
D
E
Y
A
R
I
E
N
A
G
G
K
V
I
Q
W
Q
-------
G
A
R
V
F
G
V
L
A
M
S
R
S
I
-
G
D
R
Y
LKPYVI
P
E
P
E
V
T
F
M
--
P
R
S
R
E
D
E
C
L
I
L
A
S
D
G
L
W
D
V
M
N
N
Q
E
V
C
E
I
A
R
R
R
I
L
M
W
H
K
K
NGAPRGKGID
P
A
C
Q
A
A
A
D
Y
L
S
M
L
A
L
Q
K
G
S
K
D
N
I
S
I
I
V
I
D
L
K
A
Q
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
68.79
38%
-73
- C6 -
2J86
3
?
A:
[4-240]
----------
A
G
L
T
D
C
G
L
I
R
K
S
N
Q
D
A
F
-----
Y
I
DE
K
-----
H
----------------------------
Q
R
F
F
I
V
A
D
G
M
G
--
G
H
A
G
G
E
E
A
S
R
L
A
V
D
H
I
R
Q
Y
L
E
T
H
L
E
D
L
Q
H
----------------
D
P
V
T
L
L
R
Q
A
F
L
A
A
N
H
A
I
V
E
Q
Q
R
Q
-----------
N
-
S
A
R
A
D
M
G
T
T
A
V
V
I
-
L
L
D
E
K
--
G
---
D
R
A
W
--
C
A
H
V
G
D
S
R
I
Y
R
W
R
K
D
Q
L
Q
Q
I
T
S
D
H
T
W
I
A
Q
A
V
------
Q
-----
I
E
Q
-------
A
R
Q
H
P
W
R
H
V
L
S
Q
C
L
--
G
R
E
------
D
L
S
Q
I
D
I
Q
P
I
D
L
-
E
P
G
D
R
L
L
L
C
S
D
G
L
T
E
E
L
T
D
D
V
I
S
I
Y
L
-
S
E
-----------------
P
N
V
Q
K
A
A
A
A
L
V
D
A
A
K
T
H
G
G
R
D
N
V
T
V
V
V
I
S
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
68.39
35%
-81
- C6 -
2PK0
2
?
A:
[12-245]
-------------
T
D
I
G
Q
R
R
S
N
N
Q
D
F
I
N
Q
F
E
N
K
---
A
-----
G
----------------------------
V
P
L
I
I
L
A
D
G
M
G
--
G
H
R
A
G
N
I
A
S
E
M
T
V
T
D
L
G
S
D
W
-
A
E
T
D
F
S
E
L
-------------
S
--
E
I
R
D
W
M
L
V
S
I
E
T
E
N
R
K
I
Y
-
E
L
G
Q
-----------
S
-
D
D
Y
K
G
M
G
T
T
I
E
A
V
-
A
I
--
V
--
G
---
D
N
I
I
--
F
A
H
V
G
D
S
R
I
G
I
V
R
Q
G
E
Y
H
L
L
T
S
D
H
S
L
V
N
E
L
V
------
K
A
G
Q
L
T
E
E
E
-------
A
A
S
H
P
Q
K
N
I
I
T
Q
S
I
G
Q
A
N
P
------
V
E
P
D
L
G
V
H
--
L
L
-
E
E
G
D
Y
L
V
V
N
S
D
G
L
T
N
M
L
S
N
A
D
I
A
T
V
L
T
Q
E
-----------------
K
T
L
D
D
K
N
Q
D
L
I
T
L
A
N
H
R
G
G
L
D
N
I
T
V
A
L
V
Y
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
68.16
35%
-73
- C6 -
2PK0
3
?
C:
[12-245]
-------------
T
D
I
G
Q
R
R
S
N
N
Q
D
F
I
NQFEN
K
---
A
-----
G
----------------------------
V
P
L
I
I
L
A
D
G
M
G
--
G
H
R
A
G
N
I
A
S
E
M
T
V
T
D
L
GSDW-
A
E
T
D
F
S
E
L
-------------
S
--
E
I
R
D
W
M
L
V
S
I
E
T
E
N
R
K
I
Y
-
E
L
G
Q
-----------
S
-
D
D
Y
K
G
M
G
T
T
I
E
A
V
-
A
I
--
V
--
G
---
D
N
I
I
--
F
A
H
V
G
D
S
R
I
G
I
V
R
Q
G
E
Y
H
L
L
T
S
D
H
S
L
V
N
E
L
V
------
K
A
G
Q
L
T
E
E
E
-------
A
A
S
H
P
Q
K
N
I
I
T
Q
S
I
G
Q
A
N
P
------
V
E
P
D
L
G
V
H
--
L
L
-
E
E
G
D
Y
L
V
V
N
S
D
G
L
T
N
M
L
S
N
A
D
I
A
T
V
L
T
Q
E
-----------------
K
T
L
D
D
K
N
Q
D
L
I
T
L
A
N
H
R
G
G
L
D
N
I
T
V
A
L
V
Y
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
68.00
22%
-69
- C6 -
4OIC
6
P2C06_ORYSJ
B:
[147-460]
------
V
P
L
W
G
H
K
S
I
C
G
R
-
R
P
E
M
E
D
A
V
-----
V
---
A
-----
V
S
RF
F
D
I
P
LWMLTGNSVVDGLDPMS
F
R
L
P
A
H
F
F
G
V
Y
D
G
H
G
--
G
A
Q
V
A
N
Y
C
R
E
R
L
H
A
A
L
-----
V
E
E
L
S
R
I
E
G
S
VSGANLGSVE
F
K
-
K
K
W
E
Q
A
F
V
D
C
F
S
R
V
D
E
E
V
G
G
N
---------------A
V
A
P
E
T
V
G
S
T
A
V
V
A
-
V
I
--
C
--
S
---
S
H
I
I
--
V
A
N
C
G
D
S
R
A
V
L
C
R
G
K
Q
P
V
P
L
S
V
D
H
K
P
N
R
E
D
-------
E
Y
A
R
I
E
A
E
G
G
K
V
I
QWN
G
Y
R
V
F
G
V
L
A
M
S
R
S
I
-
G
D
R
Y
LKPWII
P
V
P
E
I
T
I
V
--
P
R
A
K
D
D
E
C
L
V
L
A
S
D
G
L
W
D
V
M
S
N
E
E
V
C
D
V
A
R
K
R
I
L
L
W
H
K
K
NGSSD-----
P
A
A
E
A
A
A
E
C
L
S
K
L
A
L
Q
K
G
S
K
D
N
I
S
V
I
V
V
D
L
K
A
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
67.85
35%
-73
- C6 -
2PK0
4
?
D:
[12-245]
-------------
T
D
I
G
Q
R
R
S
N
N
Q
D
F
I
NQFEN
K
---
A
-----
G
----------------------------
V
P
L
I
I
L
A
D
G
M
G
--
G
H
R
A
G
N
I
A
S
E
M
T
V
T
D
L
GSDW-
A
E
T
D
F
S
E
L
-------------
S
--
E
I
R
D
W
M
L
V
S
I
E
T
E
N
R
K
I
Y
-
E
L
G
Q
-----------
S
-
D
D
Y
K
G
M
G
T
T
I
E
A
V
-
A
I
--
V
--
G
---
D
N
I
I
--
F
A
H
V
G
D
S
R
I
G
I
V
R
Q
G
E
Y
H
L
L
T
S
D
H
S
L
V
N
E
L
V
------
K
A
G
Q
L
T
E
E
E
-------
A
A
S
H
P
Q
K
N
I
I
T
Q
S
I
G
Q
A
N
P
------
V
E
P
D
L
G
V
H
--
L
L
-
E
E
G
D
Y
L
V
V
N
S
D
G
L
T
N
M
L
S
N
A
D
I
A
T
V
L
T
Q
E
-----------------
K
T
L
D
D
K
N
Q
D
L
I
T
L
A
N
H
R
G
G
L
D
N
I
T
V
A
L
V
Y
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
67.79
35%
-80
- C6 -
2PK0
2
?
B:
[12-245]
-------------
T
D
I
G
Q
R
R
S
N
N
Q
D
F
I
N
Q
F
E
N
K
---
A
-----
G
----------------------------
V
P
L
I
I
L
A
D
G
M
G
--
G
H
R
A
G
N
I
A
S
E
M
T
V
T
D
L
G
S
D
W
-
A
E
T
D
F
S
E
L
-------------
S
--
E
I
R
D
W
M
L
V
S
I
E
T
E
N
R
K
I
Y
-
E
L
G
Q
-----------
S
-
D
D
Y
K
G
M
G
T
T
I
E
A
V
-
A
I
--
V
--
G
---
D
N
I
I
--
F
A
H
V
G
D
S
R
I
G
I
V
R
Q
G
E
Y
H
L
L
T
S
D
H
S
L
V
N
E
L
V
------
K
A
G
Q
L
T
E
E
E
-------
A
A
S
H
P
Q
K
N
I
I
T
Q
S
I
G
Q
A
N
P
------
V
E
P
D
L
G
V
H
--
L
L
-
E
E
G
D
Y
L
V
V
N
S
D
G
L
T
N
M
L
S
N
A
D
I
A
T
V
L
T
Q
E
-----------------
K
T
L
D
D
K
N
Q
D
L
I
T
L
A
N
H
R
G
G
L
D
N
I
T
V
A
L
V
Y
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
67.55
38%
-76
- C6 -
2J86
3
?
B:
[4-240]
----------
A
G
L
T
D
C
G
L
I
R
K
S
N
Q
D
A
F
-----
Y
I
DE
K
-----
H
----------------------------
Q
R
F
F
I
V
A
D
G
M
G
--
G
H
A
G
G
E
E
A
S
R
L
A
V
D
H
I
R
Q
Y
L
E
T
H
L
E
D
L
Q
H
----------------
D
P
V
T
L
L
R
Q
A
F
L
A
A
N
H
A
I
V
E
Q
Q
R
Q
-----------
N
-
S
A
R
A
D
M
G
T
T
A
V
V
I
-
L
L
D
E
K
--
G
---
D
R
A
W
--
C
A
H
V
G
D
S
R
I
Y
R
W
R
K
D
Q
L
Q
Q
I
T
S
D
H
T
W
I
A
Q
A
V
------
Q
----
T
I
E
Q
-------
A
R
Q
H
P
W
R
H
V
L
S
Q
C
L
--
G
R
E
------
D
L
S
Q
I
D
I
Q
P
I
D
L
-
E
P
G
D
R
L
L
L
C
S
D
G
L
T
E
E
L
T
D
D
V
I
S
I
Y
L
-
S
E
-----------------
P
N
V
Q
K
A
A
A
A
L
V
D
A
A
K
T
H
G
G
R
D
N
V
T
V
V
V
I
S
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
65.30
38%
-70
- C6 -
2V06
3
?
A:
[5-233]
------
V
L
S
A
A
T
A
T
D
Q
G
P
V
R
E
N
N
Q
D
A
C
-----
L
---
A
-----
D
----------------------------
G
I
L
Y
A
V
A
D
G
F
G
AR
G
H
H
A
S
A
T
A
L
K
T
L
S
A
G
F
-----
A
A
A
P
D
R
D
---------------------
G
L
L
E
A
V
Q
Q
A
N
L
R
V
F
E
L
L
G
D
-----------
E
-
P
T
V
S
G
--
T
T
L
T
A
V
A
V
F
--
E
--
P
---
G
Q
G
G
P
L
V
V
N
I
G
D
S
P
L
Y
R
I
R
D
G
H
M
E
Q
L
T
D
D
H
S
V
A
G
E
L
V
------
R
M
G
E
I
T
R
H
E
-------
A
R
W
H
P
Q
R
H
L
L
T
R
A
L
G
I
G
P
H
------
I
G
P
D
V
F
G
I
--
D
C
-
G
P
G
D
R
L
L
I
S
S
D
G
L
F
A
A
A
D
E
A
L
I
V
D
A
A
-
T
S
-----------------
P
D
P
Q
V
A
V
R
R
L
V
E
V
A
N
D
A
G
G
S
D
N
T
T
V
V
V
I
D
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
65.20
38%
-79
- C6 -
2J82
3
?
A:
[2-240]
--------
D
V
A
G
L
T
D
C
G
L
I
R
K
S
N
Q
D
A
F
-----
Y
---
I
-----
D
EKH-------------------------
Q
R
F
F
I
V
A
D
G
M
-----
A
G
G
E
E
A
S
R
L
A
V
D
H
I
-----
R
Q
Y
L
E
T
H
L
EDL----------
Q
-
H
D
P
V
T
L
L
R
Q
A
F
-
A
A
N
H
A
I
V
E
Q
Q
R
Q
-----------
N
-
S
A
R
A
D
M
G
T
T
A
V
V
I
-
L
L
--
D
EK
G
---
D
R
A
W
--
C
A
H
V
G
D
S
R
I
Y
R
W
R
K
D
Q
L
Q
Q
I
T
S
D
H
T
W
I
A
Q
A
-----------------------------
R
H
V
L
S
Q
C
L
-
G
R
E
D
L-----
S
Q
I
D
I
Q
P
I
--
D
L
-
E
P
G
D
R
L
L
L
C
S
D
G
L
T
E
E
L
T
D
D
V
I
S
I
Y
L
-
S
E
-----------------
P
N
V
Q
K
A
A
A
A
L
V
D
A
A
K
T
H
G
G
R
D
N
V
T
V
V
V
I
S
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
65.19
38%
-81
- C6 -
2J82
3
?
A:
[4-240]
----------
A
G
L
T
D
C
G
L
I
R
K
S
N
Q
D
A
F
-----
Y
I
DE
K
-----
H
----------------------------
Q
R
F
F
I
V
A
D
G
M
-----
A
G
G
E
E
A
S
R
L
A
V
D
H
I
R
Q
Y
L
E
T
H
L
E
D
L
Q
H
----------------
D
P
V
T
L
L
R
Q
A
F
-
A
A
N
H
A
I
V
E
Q
Q
R
Q
-----------
N
-
S
A
R
A
D
M
G
T
T
A
V
V
I
-
L
L
D
E
K
--
G
---
D
R
A
W
--
C
A
H
V
G
D
S
R
I
Y
R
W
R
K
D
Q
L
Q
Q
I
T
S
D
H
T
W
I
A
Q
A
-----------------------------
R
H
V
L
S
Q
C
L
--
G
R
E
------
D
L
S
Q
I
D
I
Q
P
I
D
L
-
E
P
G
D
R
L
L
L
C
S
D
G
L
T
E
E
L
T
D
D
V
I
S
I
Y
L
-
S
E
-----------------
P
N
V
Q
K
A
A
A
A
L
V
D
A
A
K
T
H
G
G
R
D
N
V
T
V
V
V
I
S
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
64.26
38%
-74
- C6 -
2JFS
7
?
A:
[5-233]
------
V
L
S
A
A
T
A
T
D
Q
G
P
V
R
E
N
N
Q
D
A
C
-----
L
---
A
-----
D
----------------------------
G
I
L
Y
A
V
A
D
G
F
G
AR
G
H
H
A
S
A
T
A
L
K
T
L
S
A
G
F
-----
A
A
A
P
D
R
D
---------------------
G
L
L
E
A
V
Q
Q
A
N
L
R
V
F
E
L
L
G
D
-----------
E
-
P
T
V
S
G
--
T
T
L
T
A
V
A
V
F
--
E
--
P
---
G
Q
G
G
P
L
V
V
N
I
G
D
S
P
L
Y
R
I
R
D
G
H
M
E
Q
L
T
D
D
H
S
V
A
G
E
L
V
------
R
M
G
E
I
T
R
H
E
-------
A
R
W
H
P
Q
R
H
L
L
T
R
A
L
G
I
G
P
H
------
I
G
P
D
V
F
G
I
--
D
C
-
G
P
G
D
R
L
L
I
S
S
D
G
L
F
A
A
A
D
E
A
L
I
V
D
A
A
-
T
S
-----------------
P
D
P
Q
V
A
V
R
R
L
V
E
V
A
N
D
A
G
G
S
D
N
T
T
V
V
V
I
D
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
64.10
38%
-70
- C6 -
2JFT
6
?
A:
[5-233]
------
V
L
S
A
A
T
A
T
D
Q
G
P
V
R
E
N
N
Q
D
A
C
-----
L
---
A
-----
D
----------------------------
G
I
L
Y
A
V
A
D
G
F
G
AR
G
H
H
A
S
A
T
A
L
K
T
L
S
A
G
F
-----
A
A
A
P
D
R
D
---------------------
G
L
L
E
A
V
Q
Q
A
N
L
R
V
F
E
L
L
G
D
-----------
E
-
P
T
V
S
G
--
T
T
L
T
A
V
A
V
F
--
E
--
P
---
G
Q
G
G
P
L
V
V
N
I
G
D
S
P
L
Y
R
I
R
D
G
H
M
E
Q
L
T
D
D
H
S
V
A
G
E
L
V
------
R
M
G
E
I
T
R
H
E
-------
A
R
W
H
P
Q
R
H
L
L
T
R
A
L
G
I
G
P
H
------
I
G
P
D
V
F
G
I
--
D
C
-
G
P
G
D
R
L
L
I
S
S
D
G
L
F
A
A
A
D
E
A
L
I
V
D
A
A
-
T
S
-----------------
P
D
P
Q
V
A
V
R
R
L
V
E
V
A
N
D
A
G
G
S
D
N
T
T
V
V
V
I
D
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
64.08
37%
-75
- C6 -
2JFR
6
?
A:
[1-233]
--
G
M
A
S
V
L
S
A
A
T
A
T
D
Q
G
P
V
R
E
N
N
Q
D
A
C
-----
L
---
A
-----
D
----------------------------
G
I
L
Y
A
V
A
D
G
F
G
--
A
--
R
G
H
H
A
S
A
T
A
L
K
T
L
-----
S
A
G
F
A
A
A
P
-----------------
D
R
D
G
L
L
E
A
V
Q
Q
A
N
L
R
V
F
E
L
L
G
D
-----------
E
---
P
T
V
S
G
T
T
L
T
A
V
-
A
V
--
F
--
E
PGQ
G
G
P
L
--
V
V
N
I
G
D
S
P
L
Y
R
I
R
D
G
H
M
E
Q
L
T
D
D
H
S
V
A
G
E
L
V
------
R
M
G
E
I
T
R
H
E
-------
A
R
W
H
P
Q
R
H
L
L
T
R
A
L
-
G
I
G
P
H
-----
I
G
P
D
V
F
G
I
--
D
C
-
G
P
G
D
R
L
L
I
S
S
D
G
L
F
A
A
A
D
E
A
L
I
V
D
A
A
-
T
S
-----------------
P
D
P
Q
V
A
V
R
R
L
V
E
V
A
N
D
A
G
G
S
D
N
T
T
V
V
V
I
D
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------