@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv1264: (2016-04-30 )
MTDHVREADDANIDDLLGDLGGTARAERAKLVEWLLEQGITPDEIRATNPPLLLATRHLVGDDGTYVSAREISENYGVDLELLQRVQRAVGLARVDDPDAVVHMRADGEAAARAQRFVELGLNPDQVVLVVRVLAEGLSHAAEAMRYTALEAIMRPGATELDIAKGSQALVSQIVPLLGPMIQDMLFMQLRHMMETEAVNAGERAAGKPLPGARQVTVAFADLVGFTQLGEVVSAEELGHLAGRLAGLARDLTAPPVWFIKTIGDAVMLVCPDPAPLLDTVLKLVEVVDTDNNFPRLRAGVASGMAVSRAGDWFGSPVNVASRVTGVARPGAVLVADSVREALGDAPEADGFQWSFAGPRRLRGIRGDVRLFRVRRGATRTGSGGAAQDDDLAGSSP
Atome Classification :
(20 SA)
.........10........20........30........40......-..50........60...-.....70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250..-...-..260.......270...---------....280.......290---------------------------------------.---------....---...300.......310------.........320.......330.......340.......350.......360.......370.......380.......390.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MTDHVREADDA
N
I
D
D
L
L
G
DLGGT
A
R
A
E
R
A
K
L
V
E
W
L
L
EQGI
T
P
D
EIRA-TNP
P
L
L
L
A
T
RHLVGDDG-
T
Y
V
S
A
R
EI
S
E
NYGV
D
L
E
L
L
Q
R
V
Q
R
A
VGLARVDDPD
A
V
V
H
M
RAD
G
E
A
A
A
R
A
Q
R
F
V
E
LGL
N
P
D
Q
V
V
L
V
V
R
V
L
A
E
G
L
S
H
A
A
E
A
M
R
Y
T
A
L
E
A
I
MRPGA
T
E
L
DIAKG
S
Q
A
L
V
S
Q
I
V
P
L
L
G
P
M
I
Q
D
M
L
F
M
Q
L
R
H
M
M
E
T
EAVNAGERAAGKPLPGA
R
Q
V
T
V
A
F
A
D
L
V
G
F
T
Q
L
G
E
V
V
S
A
E
E
L
G
H
L
A
G
R
L
A
G
L
A
R
DLTA-P
P
V
-
W
F
I
K
TIG
D
A
V
M
L
VCPDP
A
---------
P
L
L
D
T
V
L
K
L
V
E
V
VDTD----------------------------------------N---------N
F
P
R
---
L
R
A
G
V
ASG
M
A
VSRA--------GDWFGS
P
V
N
V
A
S
R
V
TGVARP
G
A
V
L
V
A
D
S
V
R
E
A
LGDAPEADG
F
Q
W
SFAG
P
R
R
L
RGIRGD
V
R
L
F
R
V
RRGATRTGSGGAAQDDDLAGSSP
22
PsiBlast_CBE
96.58
100%
-125
- C3 -
1Y10
3
Y1264_MYCTU
C:
[12-377]
-----------
N
I
D
D
L
L
G
D
L
G
G
T
A
R
A
E
R
A
K
L
V
E
W
L
L
E
Q
G
I
T
P
D
E
I
R
A
-
T
N
P
P
L
L
L
A
T
R
H
L
V
G
D
D
G
-
T
Y
V
S
A
R
E
I
S
E
N
Y
G
V
D
L
E
L
L
Q
R
V
Q
R
A
V
G
L
A
R
V
D
D
P
D
A
V
V
H
M
R
A
D
G
E
A
A
A
R
A
Q
R
F
V
E
L
G
L
N
P
D
Q
V
V
L
V
V
R
V
L
A
E
G
L
S
H
A
A
E
A
M
R
Y
T
A
L
E
A
I
M
R
P
G
A
T
E
L
D
I
A
K
G
S
Q
A
L
V
S
Q
I
V
P
L
L
G
P
M
I
Q
D
M
L
F
M
Q
L
R
H
M
M
E
T
E
A
V
N
A
G
E
R
A
A
G
K
P
L
P
G
A
R
Q
V
T
V
A
F
A
D
L
V
G
F
T
Q
L
G
E
V
V
S
A
E
E
L
G
H
L
A
G
R
L
A
G
L
A
R
D
L
T
A
-
P
P
V
-
W
F
I
K
T
I
G
D
A
V
M
L
V
C
P
D
P
A
---------
P
L
L
D
T
V
L
K
L
V
E
V
V
D
T
D
----------------------------------------
N
---------
N
F
P
R
---
L
R
A
G
V
A
S
G
M
A
V
S
R
A
--------
G
D
W
F
G
S
P
V
N
V
A
S
R
V
T
G
V
A
R
P
G
A
V
L
V
A
D
S
V
R
E
A
L
G
D
A
---
D
G
F
Q
W
S
F
A
G
P
R
R
L
R
G
I
R
G
D
V
R
L
F
R
V
R
R
G
--------------------
28
HHSearch
95.54
100%
-128
- C3 -
1Y10
5
Y1264_MYCTU
A:
[14-376]
-------------
D
D
L
L
G
D
L
G
G
T
A
R
A
E
R
A
K
L
V
E
W
L
L
E
Q
G
I
T
P
D
E
I
R
A
-
T
N
P
P
L
L
L
A
T
R
H
L
V
G
D
D
G
-
T
Y
V
S
A
R
E
I
S
E
N
Y
G
V
D
L
E
L
L
Q
R
V
Q
R
A
V
G
L
A
R
V
D
D
P
D
A
V
V
H
M
R
A
D
G
E
A
A
A
R
A
Q
R
F
V
E
L
G
L
N
P
D
Q
V
V
L
V
V
R
V
L
A
E
G
L
S
H
A
A
E
A
M
R
Y
T
A
L
E
A
I
M
R
P
G
A
T
E
L
D
I
A
K
G
S
Q
A
L
V
S
Q
I
V
P
L
L
G
P
M
I
Q
D
M
L
F
M
Q
L
R
H
M
M
E
T
E
A
V
N
A
G
E
R
A
A
G
K
P
L
P
G
A
R
Q
V
T
V
A
F
A
D
L
V
G
F
T
Q
L
G
E
V
V
S
A
E
E
L
G
H
L
A
G
R
L
A
G
L
A
R
D
L
T
A
-
P
P
V
-
W
F
I
K
T
I
G
D
A
V
M
L
V
C
P
D
P
A
---------
P
L
L
D
T
V
L
K
L
V
E
V
V
D
T
D
----------------------------------------
N
---------
N
F
P
R
---
L
R
A
G
V
A
S
G
M
A
V
S
R
A
--------
G
D
W
F
G
S
P
V
N
V
A
S
R
V
T
G
V
A
R
P
G
A
V
L
V
A
D
S
V
R
E
A
L
G
D
A
---
D
G
F
Q
W
S
F
A
G
P
R
R
L
R
G
I
R
G
D
V
R
L
F
R
V
R
R
---------------------
1
PsiBlast_PDB
95.54
100%
-128
- C3 -
1Y10
5
Y1264_MYCTU
A:
[14-376]
-------------
D
D
L
L
G
D
L
G
G
T
A
R
A
E
R
A
K
L
V
E
W
L
L
E
Q
G
I
T
P
D
E
I
R
A
-
T
N
P
P
L
L
L
A
T
R
H
L
V
G
D
D
G
-
T
Y
V
S
A
R
E
I
S
E
N
Y
G
V
D
L
E
L
L
Q
R
V
Q
R
A
V
G
L
A
R
V
D
D
P
D
A
V
V
H
M
R
A
D
G
E
A
A
A
R
A
Q
R
F
V
E
L
G
L
N
P
D
Q
V
V
L
V
V
R
V
L
A
E
G
L
S
H
A
A
E
A
M
R
Y
T
A
L
E
A
I
M
R
P
G
A
T
E
L
D
I
A
K
G
S
Q
A
L
V
S
Q
I
V
P
L
L
G
P
M
I
Q
D
M
L
F
M
Q
L
R
H
M
M
E
T
E
A
V
N
A
G
E
R
A
A
G
K
P
L
P
G
A
R
Q
V
T
V
A
F
A
D
L
V
G
F
T
Q
L
G
E
V
V
S
A
E
E
L
G
H
L
A
G
R
L
A
G
L
A
R
D
L
T
A
-
P
P
V
-
W
F
I
K
T
I
G
D
A
V
M
L
V
C
P
D
P
A
---------
P
L
L
D
T
V
L
K
L
V
E
V
V
D
T
D
----------------------------------------
N
---------
N
F
P
R
---
L
R
A
G
V
A
S
G
M
A
V
S
R
A
--------
G
D
W
F
G
S
P
V
N
V
A
S
R
V
T
G
V
A
R
P
G
A
V
L
V
A
D
S
V
R
E
A
L
G
D
A
---
D
G
F
Q
W
S
F
A
G
P
R
R
L
R
G
I
R
G
D
V
R
L
F
R
V
R
R
---------------------
50
Fugue
95.36
99%
-129
- C3 -
1Y10
5
Y1264_MYCTU
A:
[14-376]
-------------
D
D
L
L
G
D
L
G
G
T
A
R
A
E
R
A
K
L
V
E
W
L
L
E
Q
G
I
T
P
D
E
I
R
A
-
T
N
P
P
L
L
L
A
T
R
H
L
V
G
D
D
G
-
T
Y
V
S
A
R
E
I
S
E
N
Y
G
V
D
L
E
L
L
Q
R
V
Q
R
A
V
G
L
A
R
V
D
D
P
D
A
V
V
H
M
R
A
D
G
E
A
A
A
R
A
Q
R
F
V
E
L
G
L
N
P
D
Q
V
V
L
V
V
R
V
L
A
E
G
L
S
H
A
A
E
A
M
R
Y
T
A
L
E
A
I
M
R
P
G
A
T
E
L
D
I
A
K
G
S
Q
A
L
V
S
Q
I
V
P
L
L
G
P
M
I
Q
D
M
L
F
M
Q
L
R
H
M
M
E
T
E
A
V
N
A
G
E
R
A
A
G
K
P
L
P
G
A
R
Q
V
T
V
A
F
A
D
L
V
G
F
T
Q
L
G
E
V
V
S
A
E
E
L
G
H
L
A
G
R
L
A
G
L
A
R
D
L
T
A
-
P
P
V
-
W
F
I
K
T
I
G
D
A
V
M
L
V
C
P
D
P
A
---------
P
L
L
D
T
V
L
K
L
V
E
V
V
D
T
D
----------------------------------------
N
---------
N
F
P
R
---
L
R
A
G
V
A
S
G
M
A
V
S
R
A
--------
G
D
W
F
G
S
P
V
N
V
A
S
R
V
T
G
V
A
R
P
G
A
V
L
V
A
D
S
V
R
E
A
L
G
D
A
D
---
G
F
Q
W
S
F
A
G
P
R
R
L
R
G
I
R
G
D
V
R
L
F
R
V
R
R
---------------------
23
PsiBlast_CBE
94.67
100%
-129
- C3 -
1Y10
4
Y1264_MYCTU
B:
[20-376]
-------------------
L
G
G
T
A
R
A
E
R
A
K
L
V
E
W
L
L
E
Q
G
I
T
P
D
E
I
R
A
-
T
N
P
P
L
L
L
A
T
R
H
L
V
G
D
D
G
-
T
Y
V
S
A
R
E
I
S
E
N
Y
G
V
D
L
E
L
L
Q
R
V
Q
R
A
V
G
L
A
R
V
D
D
P
D
A
V
V
H
M
R
A
D
G
E
A
A
A
R
A
Q
R
F
V
E
L
G
L
N
P
D
Q
V
V
L
V
V
R
V
L
A
E
G
L
S
H
A
A
E
A
M
R
Y
T
A
L
E
A
I
M
R
P
G
A
T
E
L
D
I
A
K
G
S
Q
A
L
V
S
Q
I
V
P
L
L
G
P
M
I
Q
D
M
L
F
M
Q
L
R
H
M
M
E
T
E
A
V
N
A
G
E
R
A
A
G
K
P
L
P
G
A
R
Q
V
T
V
A
F
A
D
L
V
G
F
T
Q
L
G
E
V
V
S
A
E
E
L
G
H
L
A
G
R
L
A
G
L
A
R
D
L
T
A
-
P
P
V
-
W
F
I
K
T
I
G
D
A
V
M
L
V
C
P
D
P
A
---------
P
L
L
D
T
V
L
K
L
V
E
V
V
D
T
D
----------------------------------------
N
---------
N
F
P
R
---
L
R
A
G
V
A
S
G
M
A
V
S
R
A
--------
G
D
W
F
G
S
P
V
N
V
A
S
R
V
T
G
V
A
R
P
G
A
V
L
V
A
D
S
V
R
E
A
L
G
D
A
P
E
A
D
G
F
Q
W
S
F
A
G
P
R
R
L
R
G
I
R
G
D
V
R
L
F
R
V
R
R
---------------------
21
PsiBlast_CBE
94.31
100%
-129
- C3 -
1Y10
6
Y1264_MYCTU
D:
[14-376]
-------------
D
D
L
L
G
D
L
G
G
T
A
R
A
E
R
A
K
L
V
E
W
L
L
E
Q
G
I
T
P
D
E
I
R
A
-
T
N
P
P
L
L
L
A
T
R
H
L
V
G
D
D
G
-
T
Y
V
S
A
R
E
I
S
E
N
Y
G
V
D
L
E
L
L
Q
R
V
Q
R
A
V
G
L
A
R
V
D
D
P
D
A
V
V
H
M
R
A
D
G
E
A
A
A
R
A
Q
R
F
V
E
L
G
L
N
P
D
Q
V
V
L
V
V
R
V
L
A
E
G
L
S
H
A
A
E
A
M
R
Y
T
A
L
E
A
I
M
R
P
G
A
T
E
L
D
I
A
K
G
S
Q
A
L
V
S
Q
I
V
P
L
L
G
P
M
I
Q
D
M
L
F
M
Q
L
R
H
M
M
E
T
E
A
V
N
A
G
E
R
A
A
G
K
P
L
P
G
A
R
Q
V
T
V
A
F
A
D
L
V
G
F
----
E
V
V
S
A
E
E
L
G
H
L
A
G
R
L
A
G
L
A
R
D
L
T
A
-
P
P
V
-
W
F
I
K
T
I
G
D
A
V
M
L
V
C
P
D
P
A
---------
P
L
L
D
T
V
L
K
L
V
E
V
V
D
T
D
----------------------------------------
N
---------
N
F
P
R
---
L
R
A
G
V
A
S
G
M
A
V
S
R
A
--------
G
D
W
F
G
S
P
V
N
V
A
S
R
V
T
G
V
A
R
P
G
A
V
L
V
A
D
S
V
R
E
A
L
G
D
A
---
D
G
F
Q
W
S
F
A
G
P
R
R
L
R
G
I
R
G
D
V
R
L
F
R
V
R
R
---------------------
2
PsiBlast_PDB
94.05
100%
-132
- C3 -
1Y11
3
Y1264_MYCTU
A:
[14-377]
-------------
D
D
L
L
G
D
L
G
G
T
A
R
A
E
R
A
K
L
V
E
W
L
L
E
Q
G
I
T
P
D
E
I
R
A
-
T
N
P
P
L
L
L
A
T
R
H
L
V
G
D
D
G
-
T
Y
V
S
A
R
E
I
S
E
N
Y
G
V
D
L
E
L
L
Q
R
V
Q
R
A
V
G
L
A
R
V
D
D
P
D
A
V
V
H
M
R
A
D
G
E
A
A
A
R
A
Q
R
F
V
E
L
G
L
N
P
D
Q
V
V
L
V
V
R
V
L
A
E
G
L
S
H
A
A
E
A
M
R
Y
T
A
L
E
A
I
M
R
P
G
A
T
E
L
D
I
A
K
G
S
Q
A
L
V
S
Q
I
V
P
L
L
G
P
M
I
Q
D
M
L
F
M
Q
L
R
H
M
M
E
T
E
A
V
N
A
G
E
R
A
A
G
K
P
L
P
G
A
R
Q
V
T
V
A
F
A
D
L
V
G
F
T
Q
L
G
E
V
V
S
A
E
E
L
G
H
L
A
G
R
L
A
G
L
A
R
D
L
T
A
-
P
P
V
-
W
F
I
K
T
I
G
D
A
V
M
L
V
C
P
D
P
A
---------
P
L
L
D
T
V
L
K
L
V
E
V
V
D
T
D
----------------------------------------
N
---------
N
F
P
R
---
L
R
A
G
V
A
S
G
M
A
V
S
R
A
--------
G
D
W
F
G
S
P
V
N
V
A
S
R
V
T
G
V
A
R
P
G
A
V
L
V
A
D
S
V
R
E
A
L
G
D
A
P
E
A
D
G
F
Q
W
S
F
A
G
P
R
R
L
R
G
I
R
G
D
V
R
L
F
R
V
R
R
G
--------------------
3
PsiBlast_PDB
61.30
99%
-110
- C3 -
2EV1
3
Y1264_MYCTU
A:
[23-207]
----------
A
N
I
D
D
L
L
G
D
L
G
G
T
A
R
A
E
R
A
K
L
V
E
W
L
L
E
Q
G
I
T
P
D
E
I
R
A
-
T
N
P
P
L
L
L
A
T
R
H
L
V
G
D
D
G
-
T
Y
V
S
A
R
E
I
S
E
N
Y
G
V
D
L
E
L
L
Q
R
V
Q
R
A
V
G
L
A
R
V
D
D
P
D
A
V
V
H
M
R
A
D
G
E
A
A
A
R
A
Q
R
F
V
E
L
G
L
N
P
D
Q
V
V
L
V
V
R
V
L
A
E
G
L
S
H
A
A
E
A
M
R
Y
T
A
L
E
A
I
M
R
P
G
A
T
E
L
D
I
A
K
G
S
Q
A
L
V
S
Q
I
V
P
L
L
G
P
M
I
Q
D
M
L
F
M
Q
L
R
H
M
M
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
60.69
99%
-105
- C3 -
2EV2
2
Y1264_MYCTU
B:
[24-206]
-----------
N
I
D
D
L
L
G
D
L
G
G
T
A
R
A
E
R
A
K
L
V
E
W
L
L
E
Q
G
I
T
P
D
E
I
R
A
-
T
N
P
P
L
L
L
A
T
R
H
L
V
G
D
D
G
-
T
Y
V
S
A
R
E
I
S
E
N
Y
G
V
D
L
E
L
L
Q
R
V
Q
R
A
V
G
L
A
R
V
D
D
P
D
A
V
V
H
M
R
A
D
G
E
A
A
A
R
A
Q
R
F
V
E
L
G
L
N
P
D
Q
V
V
L
V
V
R
V
L
A
E
G
L
S
H
A
A
E
A
M
R
Y
T
A
L
E
A
I
M
R
P
G
A
T
E
L
D
I
A
K
G
S
Q
A
L
V
S
Q
I
V
P
L
L
G
P
M
I
Q
D
M
L
F
M
Q
L
R
H
M
M
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
60.55
99%
-107
- C3 -
2EV4
2
Y1264_MYCTU
B:
[24-206]
-----------
N
I
D
D
L
L
G
D
L
G
G
T
A
R
A
E
R
A
K
L
V
E
W
L
L
E
Q
G
I
T
P
D
E
I
R
A
-
T
N
P
P
L
L
L
A
T
R
H
L
V
G
D
D
G
-
T
Y
V
S
A
R
E
I
S
E
N
Y
G
V
D
L
E
L
L
Q
R
V
Q
R
A
V
G
L
A
R
V
D
D
P
D
A
V
V
H
M
R
A
D
G
E
A
A
A
R
A
Q
R
F
V
E
L
G
L
N
P
D
Q
V
V
L
V
V
R
V
L
A
E
G
L
S
H
A
A
E
A
M
R
Y
T
A
L
E
A
I
M
R
P
G
A
T
E
L
D
I
A
K
G
S
Q
A
L
V
S
Q
I
V
P
L
L
G
P
M
I
Q
D
M
L
F
M
Q
L
R
H
M
M
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
60.40
99%
-107
- C3 -
2EV4
3
Y1264_MYCTU
A:
[23-208]
----------
A
N
I
D
D
L
L
G
D
L
G
G
T
A
R
A
E
R
A
K
L
V
E
W
L
L
E
Q
G
I
T
P
D
E
I
R
A
-
T
N
P
P
L
L
L
A
T
R
H
L
V
G
D
D
G
-
T
Y
V
S
A
R
E
I
S
E
N
Y
G
V
D
L
E
L
L
Q
R
V
Q
R
A
V
G
L
A
R
V
D
D
P
D
A
V
V
H
M
R
A
D
G
E
A
A
A
R
A
Q
R
F
V
E
L
G
L
N
P
D
Q
V
V
L
V
V
R
V
L
A
E
G
L
S
H
A
A
E
A
M
R
Y
T
A
L
E
A
I
M
R
P
G
A
T
E
L
D
I
A
K
G
S
Q
A
L
V
S
Q
I
V
P
L
L
G
P
M
I
Q
D
M
L
F
M
Q
L
R
H
M
M
E
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
60.14
97%
-107
- C3 -
2EV1
3
Y1264_MYCTU
A:
[23-207]
----------
A
N
I
D
D
L
L
G
D
L
G
G
T
A
R
A
E
R
A
K
L
V
E
W
L
L
E
Q
G
I
T
P
D
E
I
R
A
T
N
P
P
L
-
L
L
A
T
R
H
L
V
-
G
D
D
G
T
Y
V
S
A
R
E
I
S
E
N
Y
G
V
D
L
E
L
L
Q
R
V
Q
R
A
V
G
L
A
R
V
D
D
P
D
A
V
V
H
M
R
A
D
G
E
A
A
A
R
A
Q
R
F
V
E
L
G
L
N
P
D
Q
V
V
L
V
V
R
V
L
A
E
G
L
S
H
A
A
E
A
M
R
Y
T
A
L
E
A
I
M
R
P
G
A
T
E
L
D
I
A
K
G
S
Q
A
L
V
S
Q
I
V
P
L
L
G
P
M
I
Q
D
M
L
F
M
Q
L
R
H
M
M
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
59.33
99%
-110
- C3 -
2EV3
2
Y1264_MYCTU
A:
[24-207]
-----------
N
I
D
D
L
L
G
D
L
G
G
T
A
R
A
E
R
A
K
L
V
E
W
L
L
E
Q
G
I
T
P
D
E
I
R
A
-
T
N
P
P
L
L
L
A
T
R
H
L
V
G
D
D
G
-
T
Y
V
S
A
R
E
I
S
E
N
Y
G
V
D
L
E
L
L
Q
R
V
Q
R
A
V
G
L
A
R
V
D
D
P
D
A
V
V
H
M
R
A
D
G
E
A
A
A
R
A
Q
R
F
V
E
L
G
L
N
P
D
Q
V
V
L
V
V
R
V
L
A
E
G
L
S
H
A
A
E
A
M
R
Y
T
A
L
E
A
I
M
R
P
G
A
T
E
L
D
I
A
K
G
S
Q
A
L
V
S
Q
I
V
P
L
L
G
P
M
I
Q
D
M
L
F
M
Q
L
R
H
M
M
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
59.22
99%
-115
- C3 -
2EV2
2
Y1264_MYCTU
A:
[23-208]
----------
A
N
I
D
D
L
L
G
D
L
G
G
T
A
R
A
E
R
A
K
L
V
E
W
L
L
E
Q
G
I
T
P
D
E
I
R
A
-
T
N
P
P
L
L
L
A
T
R
H
L
V
G
D
D
G
-
T
Y
V
S
A
R
E
I
S
E
N
Y
G
V
D
L
E
L
L
Q
R
V
Q
R
A
V
G
L
A
R
V
D
D
P
D
A
V
V
H
M
R
A
D
G
E
A
A
A
R
A
Q
R
F
V
E
L
G
L
N
P
D
Q
V
V
L
V
V
R
V
L
A
E
G
L
S
H
A
A
E
A
M
R
Y
T
A
L
E
A
I
M
R
P
G
A
T
E
L
D
I
A
K
G
S
Q
A
L
V
S
Q
I
V
P
L
L
G
P
M
I
Q
D
M
L
F
M
Q
L
R
H
M
M
E
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
58.47
99%
-111
- C3 -
2EV1
3
Y1264_MYCTU
B:
[25-205]
------------
I
D
D
L
L
G
D
L
G
G
T
A
R
A
E
R
A
K
L
V
E
W
L
L
E
Q
G
I
T
P
D
E
I
R
A
-
T
N
P
P
L
L
L
A
T
R
H
L
V
G
D
D
G
-
T
Y
V
S
A
R
E
I
S
E
N
Y
G
V
D
L
E
L
L
Q
R
V
Q
R
A
V
G
L
A
R
V
D
D
P
D
A
V
V
H
M
R
A
D
G
E
A
A
A
R
A
Q
R
F
V
E
L
G
L
N
P
D
Q
V
V
L
V
V
R
V
L
A
E
G
L
S
H
A
A
E
A
M
R
Y
T
A
L
E
A
I
M
R
P
G
A
T
E
L
D
I
A
K
G
S
Q
A
L
V
S
Q
I
V
P
L
L
G
P
M
I
Q
D
M
L
F
M
Q
L
R
H
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
58.36
99%
-109
- C3 -
2EV3
2
Y1264_MYCTU
B:
[23-207]
----------
A
N
I
D
D
L
L
G
D
L
G
G
T
A
R
A
E
R
A
K
L
V
E
W
L
L
E
Q
G
I
T
P
D
E
I
R
A
-
T
N
P
P
L
L
L
A
T
R
H
L
V
G
D
D
G
-
T
Y
V
S
A
R
E
I
S
E
N
Y
G
V
D
L
E
L
L
Q
R
V
Q
R
A
V
G
L
A
R
V
D
D
P
D
A
V
V
H
M
R
A
D
G
E
A
A
A
R
A
Q
R
F
V
E
L
G
L
N
P
D
Q
V
V
L
V
V
R
V
L
A
E
G
L
S
H
A
A
E
A
M
R
Y
T
A
L
E
A
I
M
R
P
G
A
T
E
L
D
I
A
K
G
S
Q
A
L
V
S
Q
I
V
P
L
L
G
P
M
I
Q
D
M
L
F
M
Q
L
R
H
M
M
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
56.10
28%
-129
* C3 *
4WP9
6
?
A:
[5-173]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
S
R
V
V
I
L
F
T
D
I
E
E
S
T
A
L
N
E
R
I
G
D
R
A
W
V
K
L
I
S
S
H
D
K
L
V
S
D
L
V
R
R
Q
S
G
-
H
V
V
K
S
Q
G
D
G
F
M
V
A
F
A
R
P
E
---------
Q
A
V
R
C
G
I
E
L
Q
R
A
L
R
R
N
A--------------------------------------------------
E
I
R
---
V
R
I
G
I
H
M
G
R
S
V
R
R
G
--------
D
D
L
F
G
R
N
V
A
M
A
A
R
V
A
A
Q
A
A
G
G
E
I
L
V
S
Q
P
V
R
D
A
L
S
R
S
---
D
G
I
R
F
D
D
G
R
E
V
E
L
K
G
F
S
G
T
Y
R
L
F
A
V
L
A
S
--------------------
37
HHSearch
55.85
22%
-106
- C3 -
1FX2
2
A:
[9-224]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
D
P
V
T
L
I
F
T
D
I
E
S
S
T
A
L
W
A
A
-
H
P
D
L
M
P
D
A
V
A
A
H
H
R
M
V
R
S
L
I
G
R
Y
K
C
-
Y
E
V
K
T
V
G
D
S
F
M
I
A
S
K
S
P
F
---------
A
A
V
Q
L
A
Q
E
L
Q
L
C
F
L
H
H
DWGTN
A
L
D
D
S
Y
R
E
F
E
E
Q
R
A
E
G
E
C
EYTPPTAHMD
P
E
V
Y
S
R
L
W
---------
N
G
L
R
---
V
R
V
G
I
H
T
G
L
C
D
I
R
H
DEVTK
G
--
Y
D
Y
Y
G
R
T
P
N
M
A
A
R
T
E
S
V
A
N
G
G
Q
V
L
M
T
H
A
A
Y
M
S
L
S
A
E
D
-
R
K
Q
I
D
V
T
A
L
G
D
V
A
L
R
G
V
S
D
P
V
K
M
Y
Q
L
N
T
V
P
S
R
N
F
---------------
12
PsiBlast_PDB
54.86
28%
-132
- C3 -
4WP8
4
?
A:
[8-170]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
V
I
L
F
T
D
I
E
E
S
T
A
L
N
E
R
I
G
D
R
A
W
V
K
L
I
S
S
H
D
K
L
V
S
D
L
V
R
-
R
Q
S
G
H
V
V
K
S
Q
G
D
G
F
M
V
A
F
A
R
P
E
---------
Q
A
V
R
C
G
I
E
L
Q
R
A
L
R
R
N
----------------------------------------
A
---------
N
R
--E
I
R
V
R
I
G
I
H
M
G
R
S
V
R
R
G
--------
D
D
L
F
G
R
N
V
A
M
A
A
R
V
A
A
Q
A
A
G
G
E
I
L
V
S
Q
P
V
R
D
A
L
-------
G
I
R
F
D
D
G
R
E
V
E
L
K
G
F
S
G
T
Y
R
L
F
A
V
-----------------------
42
HHSearch
54.82
22%
-127
- C3 -
3R5G
1
?
A:
[6-195]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
R
K
K
L
T
V
F
F
S
D
I
R
G
F
T
E
L
S
E
E
L
E
A
E
A
L
T
D
L
L
N
N
Y
L
N
E
M
S
K
I
A
L
K
Y
G
G
-
T
I
D
K
F
V
G
D
C
V
M
V
F
F
G
D
P
S
TQG
A
K
K
D
A
V
A
A
V
S
M
G
I
A
M
R
K
H
M
K
V
L
----------------------------------------
R
Q
Q
W
R
A
Q
GIT
K
P
L
E
---
I
R
M
G
I
N
T
G
Y
C
T
V
G
N
F
G
A
DTRMD
Y
T
I
I
G
R
E
V
N
L
A
S
R
L
E
S
A
S
E
A
G
E
I
L
I
S
H
E
T
Y
S
L
I
K
D
V
-----
I
M
C
R
D
K
G
Q
I
A
V
K
G
F
S
R
P
V
Q
I
Y
Q
V
V
D
S
R
R
------------------