@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv1667c: (2016-05-04 )
MLGRLRGGYQVEGREVTPTQLLERLGFRRDQLSARVDDLSGGQRRRLQLMLTLLSEPNVLLLDEPTNDVDTEMLTATEDLLDSWAGTLIVVSHDRYLLERVTDQQYAILDDRLRHLPGGIDEYLQLAARVSAPAPAERPAPPAMSGAQRRATEKELAAVDRQLARLADRVAAKHTELAEHDQSDHVGITRLTQQLRVLQDHVAAMENRWLELSEMLE
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20....-..--..30........40........50........60........70----.----.......80...----..---...90........100.-......110......--..120..-.....130.......140.......150.......-----160.......170.......180.......190.......200.......210.....------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLGRLRGG
Y
Q
V
EGREV
T
P
T
Q
L
L
E
R
L-GF--
R
R
D
Q
L
S
A
R
VDDLSGG
Q
R
R
R
L
Q
L
M
L
T
L
LSEP
N
V
L
L
L
DEPTNDV
D
T
----
E
----
M
L
T
A
T
E
D
L
L
D
SW----A
G
---
T
L
I
V
V
SH
D
R
Y
L
L
E
R
VTD-Q
Q
Y
A
I
L
D
-
D
R
L
R
HLP--G
G
I
D
E
Y
L
-
Q
L
A
A
RVSAPAPAERPAPPAMSG
A
Q
RR
A
T
E
K
E
L
A
A
V
-----
D
R
Q
L
A
R
L
A
D
R
V
A
A
K
H
T
E
L
AEHDQSDH
V
G
I
T
R
L
T
Q
Q
L
R
V
L
Q
D
H
V
A
A
M
E
N
R
W
L
E
L
S
E
MLE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
74.69
33%
-65
- C3 -
4FIN
5
ETTA_ECOLI
A:
[158-313]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
I
A
N
L
S
G
G
E
R
R
R
V
A
L
C
R
L
L
L
E
K
P
D
M
L
L
L
D
E
P
T
N
H
L
D
A
----
E
----
S
V
A
W
L
E
R
F
L
H
D
F
----
E
G
---
T
V
V
A
I
T
H
D
R
Y
F
L
D
N
V
A
G
---
W
I
L
E
L
-
D
R
G
E
G
I
P
W
E
G
N
Y
S
S
W
L
E
Q
K
D
Q
R
L
A
Q
E
A
S
Q
E
--------
A
A
R
R
K
S
I
E
K
E
L
E
W
V
R
QGTK-
K
G
K
A
R
L
A
R
F
E
E
L
N
S
T
E
Y
Q
K
R
N
E
T
N
E
L
F
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
71.59
30%
-78
- C3 -
2IWH
5
EF3A_YEAST
A:
[522-635]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
T
K
E
A
I
K
D
K
L
I
E
-
F
-
G
F
--
T
D
E
M
I
A
M
P
I
S
A
L
S
G
G
W
K
M
K
L
A
L
A
R
A
V
L
R
N
A
D
I
L
L
L
D
E
P
T
N
H
L
D
T
----
V
----
N
V
A
W
L
V
N
Y
L
N
T
C
----
G
I
---
T
S
I
T
I
S
H
D
S
V
F
L
D
N
V
C
E
-
Y
I
I
N
Y
E
G
-
L
K
L
R
K
Y
K
--
G
N
F
T
E
F
V
-
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
70.90
30%
-78
- C3 -
2IW3
3
EF3A_YEAST
A:
[522-635]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
T
K
E
A
I
K
D
K
L
I
E
-
F
-
G
F
--
T
D
E
M
I
A
M
P
I
S
A
L
S
G
G
W
K
M
K
L
A
L
A
R
A
V
L
R
N
A
D
I
L
L
L
D
E
P
T
N
H
L
D
T
----
V
----
N
V
A
W
L
V
N
Y
L
N
T
C
----
G
I
---
T
S
I
T
I
S
H
D
S
V
F
L
D
N
V
C
E
-
Y
I
I
N
Y
E
G
-
L
K
L
R
K
Y
K
--
G
N
F
T
E
F
V
-
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
163
HHSearch
70.67
37%
-86
- C3 -
4FIN
4
ETTA_ECOLI
A:
[425-535]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
A
Y
V
G
R
F
-
N
F
--
K
G
V
D
Q
G
K
R
V
G
E
L
S
G
G
E
R
G
R
L
H
L
A
K
L
L
Q
V
G
G
N
M
L
L
L
D
E
P
T
N
D
L
D
I
----
E
----
T
L
R
A
L
E
N
A
L
L
E
F
----
P
G
---
C
A
M
V
I
S
H
D
R
W
F
L
D
R
I
A
T
-
H
I
L
D
Y
Q
D
E
G
K
V
E
F
F
E
--
G
N
F
T
E
Y
E
-
E
Y
K
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
70.54
30%
-73
- C3 -
2IX3
4
EF3A_YEAST
A:
[522-635]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
T
K
E
A
I
K
D
K
L
I
E
-
F
-
G
F
--
T
D
E
M
I
A
M
P
I
S
A
L
S
G
G
W
K
M
K
L
A
L
A
R
A
V
L
R
N
A
D
I
L
L
L
D
E
P
T
N
H
L
D
T
----
V
----
N
V
A
W
L
V
N
Y
L
N
T
C
----
G
I
---
T
S
I
T
I
S
H
D
S
V
F
L
D
N
V
C
E
-
Y
I
I
N
Y
E
G
-
L
K
L
R
K
Y
K
--
G
N
F
T
E
F
V
-
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
166
HHSearch
67.59
29%
-72
- C3 -
2IW3
3
EF3A_YEAST
A:
[526-636]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
I
K
D
K
L
I
E
F
-
G
F
--
T
D
E
M
I
A
M
P
I
S
A
L
S
G
G
W
K
M
K
L
A
L
A
R
A
V
L
R
N
A
D
I
L
L
L
D
E
P
T
N
H
L
D
T
----
V
----
N
V
A
W
L
V
N
Y
L
N
T
C
----
G
I
---
T
S
I
T
I
S
H
D
S
V
F
L
D
N
V
C
E
-
Y
I
I
N
Y
E
G
-
L
K
L
R
K
Y
K
--
G
N
F
T
E
F
V
-
K
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
65.46
36%
-82
- C2 -
4U00
2
?
A:
[121-207]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
L
E
R
V
-
G
I
--
L
-
D
Q
A
R
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
----
M
V
G
E
V
L
D
V
M
R
D
L
----
A
Q
G
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
-
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
142
Fugue
65.29
14%
-50
- C3 -
1YQT
4
?
A:
[24-538]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EEDCVHRYGVN
A
F
V
L
Y
R
L
P
V
V
K
E
G
M
V
V
G
I
V
G
P
N
GTG
K
S
T
A
V
K
I
L
A
GQLIPNLCGDNDS
W
D
G
V
I
R
A
F
RGNEL
Q
N
Y
F
E
K
L
K
N
GE
I
R
P
V
V
KPQYVDLIPKA
V
K
G
K
V
I
E
L
L
K
K
A
D
E
T
G
K
L
E
E
V
V
K
A
L
-
E
L
--
E
-
N
V
L
E
R
E
I
Q
H
L
S
G
G
E
L
Q
R
V
A
I
A
A
A
L
L
R
N
A
T
F
Y
F
F
D
E
P
S
S
Y
L
D
I
----
R
----
Q
R
L
N
A
A
R
A
I
R
R
L
----
S
E
E
G
K
S
V
L
V
V
E
H
D
L
A
V
L
D
Y
L
S
D
-
I
I
H
V
V
Y
G
-
E
P
G
V
---------------
Y
G
I
F
S
Q
P
K
G
T
R
N
G
I
N
E
F
L
R
G
Y
L
K
D
E
N
V
R
F
R
P
Y
-----------------
E
I
K
F
T
K
T
G
E
R
V
E
I
E
R
E
T
L
V
T
Y
P
R
L
V
K
D
Y
G
S
F
R
L
E
V
E
P
G
E
I
K
K
G
E
V
I
G
I
V
G
P
N
GIG
K
T
T
F
V
K
M
L
A
GVEEPT
E
G
K
I
E
W
D
L
T
V
A
Y
K
P
Q
Y
I
K
A
D
Y
EGT
V
Y
E
L
L
S
K
I
D
A
S
K
L
N
S
N
F
Y
K
T
E
LLKPLGIIDLYDREVNELS
G
G
E
L
Q
R
V
A
I
A
A
T
L
L
RDAD
I
Y
L
L
D
EPSAYLD
V
E
Q
R
L
A
V
S
R
A
I
R
H
L
M
E
K
N
E
K
T
A
L
V
V
E
HD
V
L
M
I
D
Y
V
SD
R
L
M
V
F
E
G
EPGK
Y
G
R
A
L
P
PMG
M
R
E
G
M
N
R
F
L
A
S
I
G
I
T
F
R
R
D
PDTG
R
P
R
A
N
K
EGS
V
K
D
R
E
Q
K
E
K
GEYYYIA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
170
HHSearch
65.15
25%
-89
- C3 -
2PJZ
1
?
A:
[107-216]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
L
E
M
L
K
A
L
-
K
L
--
G
E
E
I
L
R
R
K
L
Y
K
L
S
A
G
Q
S
V
L
V
R
T
S
L
A
L
A
S
Q
P
E
I
V
G
L
D
E
P
F
E
N
V
D
A
----
A
----
R
R
H
V
I
S
R
Y
I
K
E
Y
----
G
K
---
E
G
I
L
V
T
H
E
L
D
M
L
N
L
Y
K
E
Y
K
A
Y
F
L
V
G
-
N
R
L
Q
G
-
P
--
I
S
V
S
E
L
L
-
E
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
169
HHSearch
64.73
33%
-88
- C3 -
4FIN
4
ETTA_ECOLI
A:
[145-254]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
A
A
D
A
L
-
R
L
--
P
--
D
W
D
A
K
I
A
N
L
S
G
G
E
R
R
R
V
A
L
C
R
L
L
L
E
K
P
D
M
L
L
L
D
E
P
T
N
H
L
D
A
----
E
----
S
V
A
W
L
E
R
F
L
H
D
F
----
E
G
---
T
V
V
A
I
T
H
D
R
Y
F
L
D
N
V
A
G
-
W
I
L
E
L
D
R
-
G
E
G
I
P
W
E
--
G
N
Y
S
S
W
L
-
E
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
154
HHSearch
64.58
27%
-82
* C3 *
1OXX
11
?
K:
[119-230]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
R
V
E
E
V
A
K
I
L
-
D
I
--
H
H
-
V
L
N
H
F
P
R
E
L
S
G
A
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
----
R
----
M
R
D
S
A
R
A
L
V
K
E
V
QSRL
G
V
---
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
-
R
V
G
V
L
V
K
-
G
K
L
V
Q
-
V
--
G
K
P
E
D
L
Y
-
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
64.47
33%
-92
- C2 -
4YMS
-
?
J:
[120-211]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
A
K
V
-
G
L
LD
K
K
D
Q
Y
P
I
K
---
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
----
E
----
M
V
K
E
V
L
N
V
M
K
Q
L
----
A
N
EGM
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
--
R
V
I
F
M
D
-
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
PsiBlast_CBE
64.41
36%
-79
- C2 -
4U02
1
?
D:
[121-207]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
L
E
R
V
-
G
I
--
L
-
D
Q
A
R
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
----
M
V
G
E
V
L
D
V
M
R
D
L
----
A
Q
GGM
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
-
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
144
Fugue
64.36
20%
-25
- C3 -
4F4C
3
PGP1_CAEEL
A:
[4-1306]
N
G
S
L
R
Q
S
L
R
T
L
D
S
F
SLA
P
E
D
V
L
K
T
A
I
K
T
V
E
D
Y
EGDNIDSNG
E
I
K
I
TRDEVV
N
K
V
S
I
P
Q
L
Y
RYTT
T
L
E
K
L
L
L
F
I
G
T
L
V
A
V
I
T
G
A
G
L
P
L
M
S
I
L
Q
G
K
V
S
Q
A
F
I
N
E
Q
I
V
I
N
N
N
G
S
T
F
LPTGQNYT
K
T
D
F
E
H
D
V
M
N
V
V
W
S
Y
A
A
M
T
V
G
M
W
A
A
G
Q
I
T
V
T
C
Y
L
Y
V
A
E
Q
M
N
N
R
L
R
R
E
F
V
K
S
I
L
R
QE
I
S
W
F
D
T
N
HSGT
L
A
T
K
L
F
D
N
L
E
R
V
K
E
G
T
GD
K
I
G
M
A
F
Q
Y
L
S
Q
F
I
T
G
F
I
V
A
F
T
H
S
W
Q
L
T
L
V
M
L
A
V
T
P
I
Q
A
L
C
G
F
A
I
A
K
S
M
S
T
F
A
I
R
E
T
L
R
Y
A
K
A
G
K
V
V
E
E
T
I
S
S
I
R
T
V
V
S
L
NG
L
R
Y
E
L
E
R
Y
S
T
A
V
E
E
A
K
K
A
G
V
L
K
G
L
F
L
G
I
S
F
G
A
M
Q
A
S
N
F
I
S
F
A
L
A
F
Y
I
G
V
G
W
V
H
D
GSLN
F
G
D
M
L
T
T
F
S
S
V
M
M
G
S
M
A
L
G
L
A
G
P
Q
L
A
V
L
G
T
A
Q
G
A
A
S
G
I
Y
E
V
LDRKPVIDSS
S
K
A
G
R
KDMKIK
G
D
I
T
V
E
N
V
H
F
T
Y
PSRPDVPILRG
M
N
L
R
V
N
AGQT
V
A
L
V
G
S
SGCG
K
S
T
I
I
S
L
L
L
RYYDVL
K
G
K
I
T
I
DGVDVRDIN
L
E
F
L
R
K
N
V
A
V
V
S
Q
E
P
A
L
F
NCT
I
E
E
N
I
S
L
G
K
E
G
I
T
R
E
E
M
V
A
A
C
K
M
A
N
A
E
K
F
I
K
T
L
P
N
G
--
Y
N
T
L
V
G
D
R
G
T
Q
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
L
V
R
N
P
K
I
L
L
L
D
E
A
T
S
A
L
D
A
----
E
----
S
E
G
I
V
Q
Q
A
L
D
K
A
----
A
K
G
R
-
T
T
I
I
I
A
H
R
---
L
S
T
I
R
N
-
A
D
L
I
I
S
C
-
K
N
G
Q
V
V
E
--
V
G
D
H
R
A
L
-
M
----------
A
Q
Q
G
L
Y
Y
D
L
V
T
A
Q
T
F
T
D
A
V
D
S
A
A
E
-----
G
E
R
I
G
K
------
D
A
L
S
R
L
K
Q
E
L
E
E
N
N
A
Q
K
T
N
L
F
E
I
L
Y
H
A
R
P
H
A
L
S
L
F
I
G
M
S
T
A
T
I
G
G
F
I
Y
P
T
Y
S
V
F
F
T
S
F
M
N
V
F
AGNPADFL
S
Q
G
H
F
W
A
L
M
F
L
V
L
A
A
A
Q
G
I
C
S
F
L
M
T
F
F
M
G
I
A
S
E
S
L
T
R
D
L
R
N
K
L
F
R
N
V
L
S
QHIGFFDSPQNA
S
G
K
I
S
T
R
L
A
T
D
V
P
N
L
R
T
A
I
D
F
R
F
S
T
V
I
T
T
L
V
S
M
V
A
G
I
G
L
A
F
F
Y
G
W
Q
M
A
L
L
I
I
A
I
L
P
I
V
A
F
G
Q
Y
L
R
G
RRFTGKNVKSA
S
E
F
A
D
S
G
K
I
A
I
E
A
I
E
N
V
R
T
V
Q
A
L
AR
E
D
T
F
Y
E
N
F
C
E
K
L
D
I
P
H
K
E
A
I
K
E
A
F
I
Q
G
L
S
Y
G
C
A
S
S
V
L
Y
L
L
N
T
C
A
Y
R
M
G
L
A
L
I
I
TDPPTMQ
P
M
R
V
L
R
V
M
Y
A
I
T
I
S
T
S
TLGFAT
S
Y
F
P
E
Y
A
K
A
T
F
A
G
G
I
I
F
G
M
L
R
KISKIDSLSLAGEKKKLYGK
V
I
F
K
N
V
R
F
A
Y
PERPEIEILK
G
L
S
F
S
V
E
PG
Q
T
L
A
L
V
G
P
S
GCGKST
V
V
A
L
L
E
RFYDTL
G
G
E
I
F
I
DGSEIKTLN
P
E
H
T
R
S
Q
I
A
I
V
S
Q
E
P
T
L
F
DCS
I
A
E
N
I
I
YGLDPSSVT
M
A
Q
V
E
E
A
A
R
L
A
NI
H
N
F
I
A
E
LPEGFETRVGDRGTQLS
G
G
Q
K
Q
R
I
A
I
A
R
A
L
V
R
NPK
I
L
L
L
D
EATSALDT
E
S
E
K
V
V
Q
E
A
L
D
R
A
R
EG
R
T
C
I
V
I
A
HRLNTVMNAD
C
I
A
V
V
S
NGTII
E
K
G
T
H
T
Q
L
M
S
E
K
20
PsiBlast_PDB
64.20
31%
-92
- C2 -
4MKI
2
ECFA2_CALS4
B:
[131-217]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
I
V
-
G
I
--
S
K
E
L
A
D
K
S
P
F
E
L
S
G
G
Q
K
R
R
V
A
I
A
G
I
L
A
M
R
P
K
I
L
I
L
D
E
P
T
A
G
L
D
P
K
G
K
Q
E
----
I
L
N
K
I
K
E
I
H
D
K
Y
----
K
M
---
I
T
I
L
V
S
H
N
M
E
D
I
A
R
I
A
D
-
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
64.20
33%
-94
- C2 -
4YMW
-
?
J:
[120-211]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
A
K
V
-
G
L
LD
K
K
D
Q
Y
P
I
K
---
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
----
E
----
M
V
K
E
V
L
N
V
M
K
Q
L
----
A
N
EGM
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
--
R
V
I
F
M
D
-
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
64.18
33%
-89
- C2 -
4YMU
2
?
J:
[120-211]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
A
K
V
-
G
L
LD
K
K
D
Q
Y
P
I
K
---
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
----
E
----
M
V
K
E
V
L
N
V
M
K
Q
L
----
A
N
EGM
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
--
R
V
I
F
M
D
-
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
167
HHSearch
64.08
29%
-81
- C3 -
3RLF
3
MALK_ECOLI
A:
[112-222]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
R
V
N
Q
V
A
E
V
L
-
Q
L
--
A
H
-
L
L
D
R
K
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
----
A
----
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
---
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
-
K
I
V
V
L
D
A
-
G
R
V
A
Q
-
V
--
G
K
P
L
E
L
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
63.98
33%
-79
- C2 -
3C4J
4
?
B:
[134-228]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
K
A
E
A
K
A
M
E
L
L
D
K
V
-
G
L
--
K
-
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
----
M
V
G
E
V
L
S
V
M
K
Q
L
----
A
N
EGM
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
-
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
PsiBlast_CBE
63.82
33%
-104
- C2 -
3BK7
1
?
A:
[453-552]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
L
L
K
P
L
-
G
I
--
I
-
D
L
Y
D
R
N
V
E
D
L
S
G
G
E
L
Q
R
V
A
I
A
A
T
L
L
R
D
A
D
I
Y
L
L
D
E
P
S
A
Y
L
D
V
----
E
Q
R
L
A
V
S
R
A
I
R
H
L
M
E
K
N
----
E
K
---
T
A
L
V
V
E
H
D
V
L
M
I
D
Y
V
S
D
-
R
L
I
V
F
E
G
-
E
P
G
R
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------