@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv2832c: (2016-05-14 )
MANVQYSAVTQRYPGADAPTVDNLDLDIADGEFLVLVGPSGCGKSTTLRVLAGLEPIESGRISIGDVDVTHLPPRARDVAMVFQNYALYPNMTVAANMGFALRNAGMSRADTRRRVLEVADMLELTDLLDRKPAKLSGGQRQRVAMGRAIVRRPRVFCMDEPLSNLDAKLRVSTRSQISGLQRRLGTTTVYVTHDQVEAMTMGDRVAVLKDGVLQQVDTPRALYDDPVNTFVATFIGAPAMNLIDAAVAHGVVRAPDLAIPVPDPAAERVLVGVRPESWDVASIGTPGSLTVHVELVEELGFESFVYATPVDQRGWSSRAPRIVFRTDRRTAVRVGESLAIVPHSQEVRLFNSRTETRLR
Atome Classification :
(43 SA)
.........10.......--.20-........30........40........50........60...-----.....------70----.......-.80........90........----100........110.......120.....-..130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230......----.240..-.....-----250.-.---.-----.--.--.-...260----------.-------.------..-----..--------.-------270.......---280.---...----...----290.--......300.......310.--..---....320.......330.......340.......350.......360
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MAN
V
Q
Y
S
A
V
T
QRYPGADA--PTV-DN
L
D
L
DIADG
E
F
L
V
L
VGPSGCGKS
T
T
L
R
V
L
AGLEPIESG
R
I
S
I-----GDVDV------TH----LPP
R
A
R
D
-
V
A
M
V
F
Q
NYALYPN
M
T
V
A
ANMG----
F
A
-
L
R
NAGMS
R
A
D
T
R
R
R
V
L
E
V
A
D
M
L
E
L
T
D
-
L
LDRKPAKLSGG
Q
R
Q
R
V
A
M
G
R
A
I
VRRP
R
V
F
C
MDEPLSNLD
A
K
L
R
VS
T
R
S
Q
I
S
G
L
Q
R
RLGT
T
T
V
Y
V
THDQ
V
E
A
MTMGD
R
V
A
V
L
K
D
G
V
L
Q
QVDTP
R
A
L
YDD
P
V
N
T
F
V
A
T
F
IG
A
----
P
A
M
N
L
I
-
D
A
A
V
A-----H--G-V---V-----R--A--P-DLAIPV----------P-------D------P
A
-----
A
E
--------
R
-------
V
L
V
GVRPESW---
D
V
AS---IGT----PG
S
----
L
T
V
H
--
V
E
L
V
E
ELGFE
S
F
V
Y
ATPVDQ--RG---WSSRA
P
R
I
V
F
RTDR
R
T
A
V
RVG
E
S
L
A
IVPHSQ
E
V
R
L
FNSRTETRLR
1
PsiBlast_PDB
92.37
45%
-110
- C1 -
2D62
8
?
A:
[5-371]
-
A
E
V
K
L
I
N
I
W
K
R
F
--
G
D
V
--
T
A
V
-
K
D
L
S
L
E
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
P
T
R
G
Q
I
Y
I
-----
E
D
N
L
V
ADPEKG
V
F
----
V
P
P
K
E
R
D
-
V
A
M
V
F
Q
S
Y
A
L
Y
P
H
M
T
V
Y
D
N
I
A
----
F
P
-
L
K
L
R
K
V
P
K
Q
E
I
D
K
R
V
R
E
V
A
E
M
L
G
L
T
E
-
L
L
N
R
K
P
R
E
L
S
G
G
Q
R
Q
R
V
A
L
G
R
A
I
I
R
R
P
K
V
F
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
K
M
R
A
E
L
K
K
L
Q
R
Q
L
G
V
T
T
I
Y
V
T
H
D
Q
V
E
A
M
T
M
G
D
R
I
A
V
M
N
K
G
E
L
Q
Q
V
G
T
P
D
E
V
Y
Y
K
P
V
N
T
F
V
A
G
F
I
G
S
----
P
P
M
N
F
L
-
D
A
T
I
T
D----
D
--
G
-
F
---
L
-----
D
--
F
--
G
-
E
F
K
L
K
L
L
Q
D
Q
F
E
V
L
E
E
E
-------
N
------
M
V
-----
G
K
--------
E
-------
V
I
F
G
I
R
P
E
D
V
---
H
D
A
S
FTH
I
D
V
----
P
E
E
----
N
T
V
K
A
T
V
D
I
I
E
N
L
G
G
E
K
I
V
H
L
----
R
--
R
G
N
I
S
F
T
A
K
F
P
-------
K
E
S
K
V
R
E
G
D
E
V
S
V
V
F
D
M
K
K
I
H
I
F
R
K
D
T
E
----
107
HHSearch
92.26
45%
-103
- C1 -
3RLF
3
MALK_ECOLI
A:
[2-363]
-
A
S
V
Q
L
Q
N
V
T
K
A
W
G
E
--
V
--
V
V
S
-
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
-----
G
E
K
R
M
------
N
D
----
T
P
P
A
E
R
G
-
V
G
M
V
F
Q
S
Y
A
L
Y
P
H
L
S
V
A
E
N
M
S
----
F
G
-
L
K
L
A
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
-
L
L
D
R
K
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
----
P
K
M
N
F
L
-
P
V
K
V
T
-----
A
--
T
-
A
---
I
D
Q
V
Q
V
E
--
L
PM
P
N
R
Q
Q
V
W
L
----------
P
-------
V
ESRDV-
Q
V
-----
G
A
--------
N
-------
M
S
L
G
I
R
P
E
H
L
---
L
P
S
D
---
I
-
A
----
D
V
I
----
L
E
G
E
--
V
Q
V
V
E
Q
L
G
N
E
T
Q
I
H
I
Q
I
P
S
I
--
R
---------
Q
N
L
V
Y
R
Q
N
D
V
V
L
V
E
E
G
A
T
F
A
I
G
L
P
P
E
R
C
H
L
F
R
E
D
G
T
A
C
R
-
18
PsiBlast_PDB
91.96
43%
-107
- C1 -
3PUV
5
MALK_ECOLI
A:
[2-355]
-
A
S
V
Q
L
Q
N
V
T
K
A
W
--
G
E
V
--
V
V
S
-
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
-----
G
E
K
R
M
------
N
D
----
T
P
P
A
E
R
G
-
V
G
M
V
F
Q
S
Y
A
L
Y
P
H
L
S
V
A
E
N
M
S
----
F
G
-
L
K
L
A
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
-
L
L
D
R
K
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
----
P
K
M
N
F
L
-
P
V
K
V
T
-----
A
--
T
-
A
---
I
-----
D
--
Q
--
V
-
Q
V
E
L
P
M
----------
P
-------
N
R
Q
Q
V
W
L
P
V
-----
E
S
--------
R
DVQVG
A
N
M
S
L
G
I
R
P
E
H
L
LPS
D
I
A
D
---
V
I
L
----
E
G
E
----------
V
Q
V
V
E
Q
L
G
N
E
T
Q
I
H
I
Q
-----------
I
P
S
I
R
Q
N
L
V
Y
R
Q
N
D
V
V
L
V
E
E
G
A
T
F
A
I
G
L
P
P
E
R
C
H
L
F
---------
105
HHSearch
91.46
43%
-109
- C1 -
2YYZ
3
?
A:
[2-358]
-
P
S
I
R
V
V
N
L
K
K
Y
F
G
K
--
V
--
K
A
V
-
D
G
V
S
F
E
V
K
D
G
E
F
V
A
L
L
G
P
S
G
C
G
K
T
T
T
L
L
M
L
A
G
I
Y
K
P
T
S
G
E
I
Y
F
-----
D
D
V
L
V
------
N
D
----
I
P
P
K
Y
R
E
-
V
G
M
V
F
Q
N
Y
A
L
Y
P
H
M
T
V
F
E
N
I
A
----
F
P
-
L
R
A
R
R
I
S
K
D
E
V
E
K
R
V
V
E
I
A
R
K
L
L
I
D
N
-
L
L
D
R
K
P
T
Q
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
Q
P
K
V
L
L
F
D
E
P
L
S
N
L
D
A
N
L
R
M
I
M
R
A
E
I
K
H
L
Q
Q
E
L
G
I
T
S
V
Y
V
T
H
D
Q
A
E
A
M
T
M
A
S
R
I
A
V
F
N
Q
G
K
L
V
Q
Y
G
T
P
D
E
V
Y
D
S
P
K
N
M
F
V
A
S
F
I
G
N
----
P
P
T
N
F
L
-
R
D
F
S
V
-----
S
V
E
N
-
K
Q
--
T
-----
I
L
K
R
--
D
-
D
V
I
I
K
L
----------
P
-------
E
P
V
D
---
V
K
-----
L
K
--------
E
-------
V
V
V
G
I
R
P
E
H
C
---
R
I
S
R
---
E
R
V
----
E
N
S
----
I
P
G
V
--
V
Y
V
V
E
P
L
G
R
D
I
I
V
N
V
K
T
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G
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E
----------
I
I
K
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F
G
D
T
G
K
A
P
Q
P
G
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N
V
F
L
V
P
D
L
R
K
I
H
L
F
N
P
E
T
E
E
T
I
-
24
PsiBlast_CBE
91.39
43%
-106
- C1 -
3RLF
3
MALK_ECOLI
A:
[2-355]
-
A
S
V
Q
L
Q
N
V
T
K
A
W
--
G
E
V
--
V
V
S
-
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
-----
G
E
K
R
M
------
N
D
----
T
P
P
A
E
R
G
-
V
G
M
V
F
Q
S
Y
A
L
Y
P
H
L
S
V
A
E
N
M
S
----
F
G
-
L
K
L
A
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
-
L
L
D
R
K
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
----
P
K
M
N
F
L
-
P
V
K
V
T
-----
A
--
T
-
A
---
I
-----
D
--
Q
--
V
-
Q
V
E
L
P
M
----------
P
-------
N
R
Q
Q
V
W
L
P
V
-----
E
S
--------
R
DVQVG
A
N
M
S
L
G
I
R
P
E
H
L
LPS
D
I
A
D
---
V
I
L
----
E
G
E
----------
V
Q
V
V
E
Q
L
G
N
E
T
Q
I
H
I
Q
-----------
I
P
S
I
R
Q
N
L
V
Y
R
Q
N
D
V
V
L
V
E
E
G
A
T
F
A
I
G
L
P
P
E
R
C
H
L
F
---------
102
HHSearch
91.17
46%
-114
- C1 -
4TQU
-
?
S:
[2-362]
V
A
S
V
S
I
Q
N
V
V
K
R
Y
D
K
--
T
--
T
V
V
-
H
G
V
S
L
D
I
E
P
G
E
F
V
V
L
V
G
P
S
G
C
G
K
S
T
T
L
R
M
V
A
G
L
E
E
I
S
G
G
T
I
R
I
-----
D
G
R
V
I
------
N
D
----
L
A
P
K
D
R
D
-
V
A
M
V
F
Q
N
Y
A
L
Y
P
H
L
N
V
R
D
N
I
S
----
F
G
-
L
R
L
K
R
T
K
K
S
V
I
D
A
A
V
K
T
A
A
D
I
L
G
L
Q
P
-
L
L
E
R
K
P
S
D
L
S
G
G
Q
R
Q
R
V
A
M
G
R
A
I
V
R
D
P
K
V
F
L
F
D
Q
P
L
S
N
L
D
A
K
L
R
T
Q
M
R
A
E
I
K
R
L
H
Q
R
L
G
T
T
V
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
R
I
V
V
M
R
D
G
L
I
E
Q
I
G
K
P
M
D
L
F
L
H
P
A
N
T
F
V
A
S
F
I
G
S
----
P
P
M
N
L
M
-
P
A
R
I
A
-----
V
--
D
-
S
TQH
V
-----
E
L-
N
--
G
-
G
N
R
I
S
L
----------
L
PRAG---
T
HL----
A
P
-----
G
Q
--------
E
-------
V
V
F
G
I
R
P
E
D
V
---
T
L
D
G
---
V
E
G
SE--
R
A
Q
----
I
K
A
T
--
V
D
I
V
E
P
L
G
S
E
S
I
L
H
A
T
V
G
D
H
-------------
S
L
V
V
K
V
G
G
L
N
E
V
H
P
G
D
P
V
T
L
H
V
D
L
T
R
V
H
L
F
D
A
Q
S
Q
A
S
I
-
20
PsiBlast_PDB
91.11
43%
-106
- C1 -
3PUX
5
MALK_ECOLI
A:
[2-355]
-
A
S
V
Q
L
Q
N
V
T
K
A
W
--
G
E
V
--
V
V
S
-
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
-----
G
E
K
R
M
------
N
D
----
T
P
P
A
E
R
G
-
V
G
M
V
F
Q
S
Y
A
L
Y
P
H
L
S
V
A
E
N
M
S
----
F
G
-
L
K
L
A
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
-
L
L
D
R
K
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
----
P
K
M
N
F
L
-
P
V
K
V
T
-----
A
--
T
-
A
---
I
-----
D
--
Q
--
V
-
Q
V
E
L
P
M
----------
P
-------
N
R
Q
Q
V
W
L
P
V
-----
E
S
--------
R
DVQVG
A
N
M
S
L
G
I
R
P
E
H
L
LPS
D
I
A
D
---
V
I
L
----
E
G
E
----------
V
Q
V
V
E
Q
L
G
N
E
T
Q
I
H
I
Q
-----------
I
P
S
I
R
Q
N
L
V
Y
R
Q
N
D
V
V
L
V
E
E
G
A
T
F
A
I
G
L
P
P
E
R
C
H
L
F
---------
104
HHSearch
91.06
40%
-114
- C1 -
2IT1
-
?
A:
[1-357]
M
V
E
I
K
L
E
N
I
V
K
K
F
G
N
--
F
--
T
A
L
-
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
Y
F
-----
D
E
K
D
V
------
T
E
----
L
P
P
K
D
R
N
-
V
G
L
V
F
Q
N
W
A
L
Y
P
H
M
T
V
Y
K
N
I
A
----
F
P
-
L
E
L
R
K
A
P
R
E
E
I
D
K
K
V
R
E
V
A
K
M
L
H
I
D
K
-
L
L
N
R
Y
P
W
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
K
R
L
Q
K
E
L
G
I
T
T
V
Y
V
T
H
D
Q
A
E
A
L
A
M
A
D
R
I
A
V
I
R
E
G
E
I
L
Q
V
G
T
P
D
E
V
Y
Y
K
P
K
Y
K
F
V
G
G
F
L
G
N
----
P
P
M
N
F
V
-
E
A
K
V
E
-----
D
--
G
-
K
---
L
-----
V
I-
T
--
E
-
K
S
K
L
P
I
----------
P
KQY
V
E
I
V
K
E
-----
T
G
-----
I
T
--------
E
-------
V
I
I
G
F
R
P
H
D
A
---
E
I
V
K
---
G
E
-----
G
E
G
----
I
V
G
E
--
V
Y
S
F
E
P
L
G
R
E
Q
I
V
T
V
S
V
N
D
S
-------------
I
V
K
V
F
A
P
E
G
E
H
F
S
F
G
E
K
V
T
I
K
V
K
E
E
L
L
V
L
F
D
K
K
T
E
K
A
L
-
21
PsiBlast_CBE
90.67
43%
-104
- C1 -
4KI0
3
MALK_ECOLI
B:
[2-355]
-
A
S
V
Q
L
Q
N
V
T
K
A
W
--
G
E
V
--
V
V
S
-
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
-----
G
E
K
R
M
------
N
D
----
T
P
P
A
E
R
G
-
V
G
M
V
F
Q
S
Y
A
L
Y
P
H
L
S
V
A
E
N
M
S
----
F
G
-
L
K
L
A
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
-
L
L
D
R
K
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
----
P
K
M
N
F
L
-
P
V
K
V
T
-----
A
--
T
-
A
---
I
-----
D
--
Q
--
V
-
Q
V
E
L
P
M
----------
P
-------
N
RQQVWL
P
V
-----
E
S
--------
R
DVQVGAN
M
S
L
G
I
R
P
E
H
L
LPS
D
I
A
D
---
V
I
L
----
E
G
E
----------
V
Q
V
V
E
Q
L
G
N
E
T
Q
I
H
I
Q
-----------
I
P
S
I
R
Q
N
L
V
Y
R
Q
N
D
V
V
L
V
E
E
G
A
T
F
A
I
G
L
P
P
E
R
C
H
L
F
---------
22
PsiBlast_CBE
90.63
43%
-105
- C1 -
4KI0
4
MALK_ECOLI
A:
[2-355]
-
A
S
V
Q
L
Q
N
V
T
K
A
W
--
G
E
V
--
V
V
S
-
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
-----
G
E
K
R
M
------
N
D
----
T
P
P
A
E
R
G
-
V
G
M
V
F
Q
S
Y
A
L
Y
P
H
L
S
V
A
E
N
M
S
----
F
G
-
L
K
L
A
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
-
L
L
D
R
K
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
----
P
K
M
N
F
L
-
P
V
K
V
T
-----
A
--
T
-
A
---
I
-----
D
--
Q
--
V
-
Q
V
E
L
P
M
----------
P
-------
N
R
Q
Q
V
W
L
P
V
-----
E
S
--------
R
DVQVG
A
N
M
S
L
G
I
R
P
E
H
L
LPS
D
I
A
D
---
V
I
L
----
E
G
E
----------
V
Q
V
V
E
Q
L
G
N
E
T
Q
I
H
I
Q
-----------
I
P
S
I
R
Q
N
L
V
Y
R
Q
N
D
V
V
L
V
E
E
G
A
T
F
A
I
G
L
P
P
E
R
C
H
L
F
---------
19
PsiBlast_PDB
90.32
43%
-105
- C1 -
3PUW
5
MALK_ECOLI
A:
[2-355]
-
A
S
V
Q
L
Q
N
V
T
K
A
W
--
G
E
V
--
V
V
S
-
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
-----
G
E
K
R
M
------
N
D
----
T
P
P
A
E
R
G
-
V
G
M
V
F
Q
S
Y
A
L
Y
P
H
L
S
V
A
E
N
M
S
----
F
G
-
L
K
L
A
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
-
L
L
D
R
K
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
----
P
K
M
N
F
L
-
P
V
K
V
T
-----
A
--
T
-
A
---
I
-----
D
--
Q
--
V
-
Q
V
E
L
P
M
----------
P
-------
N
R
Q
Q
V
W
L
P
V
-----
E
S
--------
R
DVQVG
A
N
M
S
L
G
I
R
P
E
H
L
LPS
D
I
A
D
---
V
I
L
----
E
G
E
----------
V
Q
V
V
E
Q
L
G
N
E
T
Q
I
H
I
Q
-----------
I
P
S
I
R
Q
N
L
V
Y
R
Q
N
D
V
V
L
V
E
E
G
A
T
F
A
I
G
L
P
P
E
R
C
H
L
F
---------
4
PsiBlast_PDB
90.07
44%
-111
- C1 -
2YYZ
3
?
A:
[10-355]
----------
K
K
Y
F
G
K
-
V
--
K
A
V
-
D
G
V
S
F
E
V
K
D
G
E
F
V
A
L
L
G
P
S
G
C
G
K
T
T
T
L
L
M
L
A
G
I
Y
K
P
T
S
G
E
I
Y
F
-----
D
D
V
L
V
------
N
D
----
I
P
P
K
Y
R
E
-
V
G
M
V
F
Q
N
Y
A
L
Y
P
H
M
T
V
F
E
N
I
A
----
F
P
-
L
R
A
R
R
I
S
K
D
E
V
E
K
R
V
V
E
I
A
R
K
L
L
I
D
N
-
L
L
D
R
K
P
T
Q
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
Q
P
K
V
L
L
F
D
E
P
L
S
N
L
D
A
N
L
R
M
I
M
R
A
E
I
K
H
L
Q
Q
E
L
G
I
T
S
V
Y
V
T
H
D
Q
A
E
A
M
T
M
A
S
R
I
A
V
F
N
Q
G
K
L
V
Q
Y
G
T
P
D
E
V
Y
D
S
P
K
N
M
F
V
A
S
F
I
G
N
----
P
P
T
N
F
L
R
D
F
S
V
S
V
E
NK-
Q
--
T
-
I
---
L
-----
K
--
R
--
D
-
D
V
I
I
K
L
----------
P
-------
E
------
P
V
D
V
K--
L
K
--------
E
-------
V
V
V
G
I
R
P
E
H
C
---
R
I
S
R
---
E
R
V
----
E
N
S
----
I
P
G
V
--
V
Y
V
V
E
P
L
G
R
D
I
I
V
N
V
K
------------
T
E
K
G
E
I
I
K
V
F
G
D
T
G
K
A
P
Q
P
G
E
N
V
F
L
V
P
D
L
R
K
I
H
L
F
N
P
E
T
E
----
23
PsiBlast_CBE
90.03
43%
-105
- C1 -
3RLF
3
MALK_ECOLI
B:
[2-355]
-
A
S
V
Q
L
Q
N
V
T
K
A
W
--
G
E
V
--
V
V
S
-
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
-----
G
E
K
R
M
------
N
D
----
T
P
P
A
E
R
G
-
V
G
M
V
F
Q
S
Y
A
L
Y
P
H
L
S
V
A
E
N
M
S
----
F
G
-
L
K
L
A
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
-
L
L
D
R
K
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
----
P
K
M
N
F
L
-
P
V
K
V
T
-----
A
--
T
-
A
---
I
-----
D
--
Q
--
V
-
Q
V
E
L
P
M
----------
P
-------
N
RQQVWL
P
V
-----
E
S
--------
R
DVQVGAN
M
S
L
G
I
R
P
E
H
L
LPS
D
I
A
D
---
V
I
L
----
E
G
E
----------
V
Q
V
V
E
Q
L
G
N
E
T
Q
I
H
I
Q
-----------
I
P
S
I
R
Q
N
L
V
Y
R
Q
N
D
V
V
L
V
E
E
G
A
T
F
A
I
G
L
P
P
E
R
C
H
L
F
---------
36
PsiBlast_CBE
89.82
38%
-112
- C1 -
2IT1
1
?
B:
[2-358]
-
V
E
I
K
L
E
N
I
V
K
K
F
--
G
N
F
--
T
A
L
-
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
Y
F
-----
D
E
K
D
V
------
T
E
----
L
P
P
K
D
R
N
-
V
G
L
V
F
Q
N
W
A
L
Y
P
H
M
T
V
Y
K
N
I
A
----
F
P
-
L
E
L
R
K
A
P
R
E
E
I
D
K
K
V
R
E
V
A
K
M
L
H
I
D
K
-
L
L
N
R
Y
P
W
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
K
R
L
Q
K
E
L
G
I
T
T
V
Y
V
T
H
D
Q
A
E
A
L
A
M
A
D
R
I
A
V
I
R
E
G
E
I
L
Q
V
G
T
P
D
E
V
Y
Y
K
P
K
Y
K
F
V
G
G
F
L
G
N
----
P
P
M
N
F
V
-
E
A
K
V
E
-----
D
--
G
K
L
---
V
-----
I
--
T
--
E
-
K
S
K
L
P
I
----------
P
-------
K
------
Q
Y
-----
V
E
I
V
K
E
T
GIT
E
-------
V
I
I
G
F
R
P
H
D
A
---
E
I
V
K
----
G
E
----
G
E
G
----
I
V
G
E
--
V
Y
S
F
E
P
L
G
R
E
Q
I
V
T
V
S
V
N
D
S
I
V
K
V
---
F
A
P
E
G
E
H
F
S
F
--
G
E
K
V
T
I
K
V
K
E
E
L
L
V
--------
L
F
D
K
K
T
E
K
A
L
E
8
PsiBlast_PDB
89.66
45%
-110
- C1 -
4XTC
-
?
S:
[2-362]
V
A
S
V
S
I
Q
N
V
V
K
R
Y
---
D
K
--
T
T
V
V
H
G
V
S
L
D
I
E
P
G
E
F
V
V
L
V
G
P
S
G
C
G
K
S
T
T
L
R
M
V
A
G
L
E
E
I
S
G
G
T
I
R
I
-----
D
G
R
V
I
------
N
D
----
L
A
P
K
D
R
D
-
V
A
M
V
F
Q
N
Y
A
L
Y
P
H
L
N
V
R
D
N
I
S
----
F
G
-
L
R
L
K
R
T
K
K
S
V
I
D
A
A
V
K
T
A
A
D
I
L
G
L
Q
P
-
L
L
E
R
K
P
S
D
L
S
G
G
Q
R
Q
R
V
A
M
G
R
A
I
V
R
D
P
K
V
F
L
F
D
Q
P
L
S
N
L
D
A
K
L
R
T
Q
M
R
A
E
I
K
R
L
H
Q
R
L
G
T
T
V
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
R
I
V
V
M
R
D
G
L
I
E
Q
I
G
K
P
M
D
L
F
L
H
P
A
N
T
F
V
A
S
F
I
G
S
----
P
P
M
N
L
M
-
P
A
R
I
A
VDSTQ
H
--
V
-
E
---
L
-----
N
--
G
--
G
-
N
R
I
S
L
L
----------
P
-------
R
------
A
G
THLAP
G
Q
--------
E
-------
V
V
F
G
I
R
P
E
-----
D
V
T
L
---
D
G
V
----
E
G
S
ERAQ
I
K
A
T
--
V
D
I
V
E
P
L
G
S
E
S
I
L
H
A
T
V
G
D
H
-------------
S
L
V
V
K
V
G
G
L
N
E
V
H
P
G
D
P
V
T
L
H
V
D
L
T
R
V
H
L
F
D
A
Q
S
Q
A
S
I
-
16
PsiBlast_PDB
89.14
43%
-106
- C1 -
3PUZ
2
MALK_ECOLI
A:
[2-355]
-
A
S
V
Q
L
Q
N
V
T
K
A
W
--
G
E
V
--
V
V
S
-
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
-----
G
E
K
R
M
------
N
D
----
T
P
P
A
E
R
G
-
V
G
M
V
F
Q
S
Y
A
L
Y
P
H
L
S
V
A
E
N
M
S
----
F
G
-
L
K
L
A
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
-
L
L
D
R
K
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
----
P
K
M
N
F
L
-
P
V
K
V
T
-----
A
--
T
-
A
---
I
-----
D
--
Q
--
V
-
Q
V
E
L
P
M
----------
P
-------
N
R
Q
Q
V
W
L
P
V
-----
E
S
--------
R
DVQVG
A
N
M
S
L
G
I
R
P
E
H
L
LPS
D
I
A
D
---
V
I
L
----
E
G
E
----------
V
Q
V
V
E
Q
L
G
N
E
T
Q
I
H
I
Q
-----------
I
P
S
I
R
Q
N
L
V
Y
R
Q
N
D
V
V
L
V
E
E
G
A
T
F
A
I
G
L
P
P
E
R
C
H
L
F
---------
25
PsiBlast_CBE
89.11
43%
-108
- C1 -
3PUZ
2
MALK_ECOLI
B:
[2-355]
-
A
S
V
Q
L
Q
N
V
T
K
A
W
--
G
E
V
--
V
V
S
-
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
-----
G
E
K
R
M
------
N
D
----
T
P
P
A
E
R
G
-
V
G
M
V
F
Q
S
Y
A
L
Y
P
H
L
S
V
A
E
N
M
S
----
F
G
-
L
K
L
A
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
-
L
L
D
R
K
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
----
P
K
M
N
F
L
-
P
V
K
V
T
-----
A
--
T
-
A
---
I
-----
D
--
Q
--
V
-
Q
V
E
L
P
M
----------
P
-------
N
RQQVWL
P
V
-----
E
S
--------
R
DVQVGAN
M
S
L
G
I
R
P
E
H
L
LPS
D
I
A
D
---
V
I
L
----
E
G
E
----------
V
Q
V
V
E
Q
L
G
N
E
T
Q
I
H
I
Q
-----------
I
P
S
I
R
Q
N
L
V
Y
R
Q
N
D
V
V
L
V
E
E
G
A
T
F
A
I
G
L
P
P
E
R
C
H
L
F
---------
7
PsiBlast_PDB
88.94
45%
-110
- C1 -
4XIG
-
?
S:
[2-362]
V
A
S
V
S
I
Q
N
V
V
K
R
Y
---
D
K
--
T
T
V
V
H
G
V
S
L
D
I
E
P
G
E
F
V
V
L
V
G
P
S
G
C
G
K
S
T
T
L
R
M
V
A
G
L
E
E
I
S
G
G
T
I
R
I
-----
D
G
R
V
I
------
N
D
----
L
A
P
K
D
R
D
-
V
A
M
V
F
Q
N
Y
A
L
Y
P
H
L
N
V
R
D
N
I
S
----
F
G
-
L
R
L
K
R
T
K
K
S
V
I
D
A
A
V
K
T
A
A
D
I
L
G
L
Q
P
-
L
L
E
R
K
P
S
D
L
S
G
G
Q
R
Q
R
V
A
M
G
R
A
I
V
R
D
P
K
V
F
L
F
D
Q
P
L
S
N
L
D
A
K
L
R
T
Q
M
R
A
E
I
K
R
L
H
Q
R
L
G
T
T
V
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
R
I
V
V
M
R
D
G
L
I
E
Q
I
G
K
P
M
D
L
F
L
H
P
A
N
T
F
V
A
S
F
I
G
S
----
P
P
M
N
L
M
-
P
A
R
I
A
VDSTQ
H
--
V
-
E
---
L
-----
N
--
G
--
G
-
N
R
I
S
L
L
----------
P
-------
R
------
A
G
THLAP
G
Q
--------
E
-------
V
V
F
G
I
R
P
E
-----
D
V
T
L
---
D
G
V
----
E
G
S
ERAQ
I
K
A
T
--
V
D
I
V
E
P
L
G
S
E
S
I
L
H
A
T
V
G
D
H
-------------
S
L
V
V
K
V
G
G
L
N
E
V
H
P
G
D
P
V
T
L
H
V
D
L
T
R
V
H
L
F
D
A
Q
S
Q
A
S
I
-
103
HHSearch
88.75
45%
-114
- C1 -
1V43
-
?
A:
[10-372]
M
V
E
V
K
L
E
N
L
T
K
R
F
G
N
--
F
--
T
A
V
-
N
K
L
N
L
T
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
P
T
E
G
R
I
Y
F
-----
G
D
R
D
V
------
T
Y
----
L
P
P
K
D
R
N
-
I
S
M
V
F
Q
------
H
M
T
V
Y
E
N
I
A
----
F
P
-
L
--
K
K
F
P
K
D
E
I
D
K
R
V
R
W
A
A
E
L
L
Q
I
E
E
-
L
L
N
R
Y
P
A
Q
L
S
G
G
Q
R
Q
R
V
A
V
A
R
A
I
V
V
E
P
D
V
L
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
A
M
R
A
E
I
K
K
L
Q
Q
K
L
K
V
T
T
I
Y
V
T
H
D
Q
V
E
A
M
T
M
G
D
R
I
A
V
M
N
R
G
Q
L
L
Q
I
G
S
P
T
E
V
Y
L
R
P
N
S
V
F
V
A
T
F
I
G
A
----
P
E
M
N
I
L
-
E
V
S
V
G
-----
D
--
G
-
Y
---
L
-----
E
--
G
--
R
-
G
F
R
I
E
L
----------
P
-------
Q
MDLLKD
Y
V
-----
G
K
--------
T
-------
V
L
F
G
I
R
P
E
H
M
---
T
V
E
G
---
V
--HMK
R
T
A
R
----
L
I
G
K
--
V
D
F
V
E
A
L
G
T
D
T
I
L
H
V
K
F
G
D
E
-------------
L
V
K
V
K
L
P
G
H
I
P
I
E
P
G
R
E
V
K
V
I
M
D
L
D
M
I
H
V
F
D
K
D
T
E
K
A
I
-
15
PsiBlast_PDB
88.75
43%
-107
- C1 -
3PUY
3
MALK_ECOLI
A:
[2-355]
-
A
S
V
Q
L
Q
N
V
T
K
A
W
--
G
E
V
--
V
V
S
-
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
-----
G
E
K
R
M
------
N
D
----
T
P
P
A
E
R
G
-
V
G
M
V
F
Q
S
Y
A
L
Y
P
H
L
S
V
A
E
N
M
S
----
F
G
-
L
K
L
A
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
-
L
L
D
R
K
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
----
P
K
M
N
F
L
-
P
V
K
V
T
-----
A
--
T
-
A
---
I
-----
D
--
Q
--
V
-
Q
V
E
L
P
M
----------
P
-------
N
R
Q
Q
V
W
L
P
V
-----
E
S
--------
R
DVQVG
A
N
M
S
L
G
I
R
P
E
H
L
LPS
D
I
A
D
---
V
I
L
----
E
G
E
----------
V
Q
V
V
E
Q
L
G
N
E
T
Q
I
H
I
Q
-----------
I
P
S
I
R
Q
N
L
V
Y
R
Q
N
D
V
V
L
V
E
E
G
A
T
F
A
I
G
L
P
P
E
R
C
H
L
F
---------
49
PsiBlast_CBE
62.14
34%
-101
- C1 -
3FVQ
3
FBPC_NEIG1
B:
[16-296]
----------------
N
T
--
P
V
L
-
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
-----
S
G
K
T
I
FSKN--
T
N
----
L
P
V
R
E
R
R
-
L
G
Y
L
V
Q
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
A
----
Y
G
-
L
G
N
G
K
G
R
T
A
Q
E
R
Q
R
I
E
A
M
L
E
L
T
G
I
S
E
-
L
A
G
R
Y
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
P
A
D
L
D
A
A
L
F
I
G
E
GIVF
P
A
A
L
N
A
-
D
G
T
A
D
-----
C
--
R
-
L
---
G
-----
R
--
L
--
P
----
V
Q
S
----------
G
-------
A
------
P
A
-----
G
T
--------
R
-------
G
T
L
L
I
R
P
E
Q
Y
---
S
L
H
P
---
H
S
A
----
P
A
A
-----
S
I
H
--------------------------------------------------------------------------
50
PsiBlast_CBE
61.17
34%
-100
- C1 -
3FVQ
3
FBPC_NEIG1
A:
[16-301]
----------------
N
T
--
P
V
L
-
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
-----
S
G
K
T
I
FSKN--
T
N
----
L
P
V
R
E
R
R
-
L
G
Y
L
V
Q
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
A
----
Y
G
-
L
G
N
G
K
G
R
T
A
Q
E
R
Q
R
I
E
A
M
L
E
L
T
G
I
S
E
-
L
A
G
R
Y
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
P
A
D
L
D
A
A
L
F
I
G
E
G
I
V
F
P
A
A
L
N
A
-
D
G
T
A
D
-----
C
--
R
-
L
---
G
-----
R
--
L
--
P
----
V
Q
S
----------
G
-------
A
------
P
A
-----
G
T
--------
R
-------
G
T
L
L
I
R
P
E
Q
Y
---
S
L
H
P
---
H
S
A
----
P
A
A
-----
S
I
H
--------------------------------------------------------------------------
57
PsiBlast_CBE
53.86
34%
-94
- C1 -
3C4J
4
?
B:
[40-259]
----------------------
L
-
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
-----
D
G
I
N
L
KAKD--
T
N
----
L
N
K
V
R
E
E
-
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
----
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
79
PsiBlast_CBE
53.43
33%
-90
- C1 -
4U00
3
?
A:
[19-238]
---------------------
V
L
-
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
-----
D
G
L
S
V
------
K
D
DRA-
L
R
E
I
R
R
E
-
V
G
M
V
F
Q
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
----
L
A
P
M
R
V
R
R
W
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
L
D
-
Q
A
R
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
Q
G
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
T
R
S
F
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
70
PsiBlast_CBE
52.79
34%
-93
- C1 -
2OLJ
4
?
A:
[40-259]
----------------------
L
-
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
-----
D
G
I
N
L
KAKD--
T
N
----
L
N
K
V
R
E
E
-
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
----
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
73
PsiBlast_CBE
52.67
34%
-92
- C1 -
3TIF
7
Y796_METJA
B:
[2-232]
---
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
II
Y
A
L
-
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
DNIKT
N
D
L
D
D
------
D
E
----
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
LPLI
F
K
-
Y
R
G
A
-
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
F
A
N
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
-
I
N
V
A
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
E
E
K
L
R
G
-
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
55
PsiBlast_CBE
52.33
35%
-95
- C1 -
3C41
3
?
K:
[22-238]
--------------------------
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
-----
D
G
I
N
L
KAKD--
T
N
----
L
N
K
V
R
E
E
-
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
----
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
69
PsiBlast_CBE
52.29
34%
-86
- C1 -
2OLJ
3
?
B:
[40-259]
----------------------
L
-
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
-----
D
G
I
N
L
KAKD--
T
N
----
L
N
K
V
R
E
E
-
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
----
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
56
PsiBlast_CBE
52.23
35%
-93
- C1 -
3C41
3
?
J:
[22-238]
--------------------------
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
-----
D
G
I
N
L
KAKD--
T
N
----
L
N
K
V
R
E
E
-
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
----
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
66
PsiBlast_CBE
52.12
34%
-90
- C1 -
2OLK
1
?
C:
[40-259]
----------------------
L
-
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
-----
D
G
I
N
L
KAKD--
T
N
----
L
N
K
V
R
E
E
-
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
----
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
71
PsiBlast_CBE
52.08
34%
-91
- C1 -
1L2T
4
Y796_METJA
B:
[2-232]
---
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
II
Y
A
L
-
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
DNIKT
N
D
L
D
D
------
D
E
----
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
LPLI
F
K
-
Y
R
G
A
-
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
F
A
N
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
-
I
N
V
A
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
E
E
K
L
R
G
-
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
58
PsiBlast_CBE
52.00
34%
-93
- C1 -
3C4J
3
?
A:
[40-259]
----------------------
L
-
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
-----
D
G
I
N
L
KAKD--
T
N
----
L
N
K
V
R
E
E
-
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
----
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
65
PsiBlast_CBE
51.56
34%
-91
- C1 -
2OLK
1
?
D:
[40-259]
----------------------
L
-
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
-----
D
G
I
N
L
KAKD--
T
N
----
L
N
K
V
R
E
E
-
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
----
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
59
PsiBlast_CBE
51.20
34%
-93
- C1 -
2Q0H
4
?
B:
[40-259]
----------------------
L
-
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
-----
D
G
I
N
L
KAKD--
T
N
----
L
N
K
V
R
E
E
-
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
----
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
67
PsiBlast_CBE
51.12
34%
-93
- C1 -
2OLK
2
?
B:
[40-259]
----------------------
L
-
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
-----
D
G
I
N
L
KAKD--
T
N
----
L
N
K
V
R
E
E
-
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
----
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
60
PsiBlast_CBE
51.04
34%
-93
- C1 -
2Q0H
4
?
A:
[40-259]
----------------------
L
-
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
-----
D
G
I
N
L
KAKD--
T
N
----
L
N
K
V
R
E
E
-
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
----
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
68
PsiBlast_CBE
50.87
34%
-92
- C1 -
2OLK
1
?
A:
[40-259]
----------------------
L
-
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
-----
D
G
I
N
L
KAK
D
--
T
N
----
L
N
K
V
R
E
E
-
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
----
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
83
PsiBlast_CBE
50.63
34%
-93
- C1 -
4YMU
2
?
A:
[22-224]
----------------------------
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
-----
D
G
V
K
I
------
N
N
GKVN
I
N
K
V
R
Q
K
-
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
----
L
A
P
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
72
PsiBlast_CBE
50.41
34%
-89
- C1 -
1L2T
4
Y796_METJA
A:
[2-230]
---
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
-
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
DNIKT
N
D
L
D
D
------
D
E
----
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
PLI
F
K
-
Y
R
G
A
-
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
F
A
N
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
-
I
N
V
A
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
E
E
K
L
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
74
PsiBlast_CBE
50.39
34%
-89
- C1 -
3TIF
7
Y796_METJA
A:
[2-230]
---
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
-
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
DNIKT
N
D
L
D
D
------
D
E
----
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
PLI
F
K
-
Y
R
G
A
-
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
F
A
N
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
-
I
N
V
A
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
E
E
K
L
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
82
PsiBlast_CBE
49.03
34%
-92
- C1 -
4YMU
2
?
J:
[22-224]
----------------------------
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
-----
D
G
V
K
I
------
N
N
GKVN
I
N
K
V
R
Q
K
-
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
----
L
A
P
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
81
PsiBlast_CBE
48.48
34%
-90
- C1 -
4YMV
1
?
A:
[22-224]
----------------------------
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
-----
D
G
V
K
I
------
N
N
GKVN
I
N
K
V
R
Q
K
-
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
----
L
A
P
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
80
PsiBlast_CBE
48.06
34%
-93
- C1 -
4YMV
1
?
J:
[22-224]
----------------------------
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
-----
D
G
V
K
I
------
N
N
GKVN
I
N
K
V
R
Q
K
-
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
----
L
A
P
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------