@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv3877: (2016-05-24 )
MSAPAVAAGPTAAGATAARPATTRVTILTGRRMTDLVLPAAVPMETYIDDTVAVLSEVLEDTPADVLGGFDFTAQGVWAFARPGSPPLKLDQSLDDAGVVDGSLLTLVSVSRTERYRPLVEDVIDAIAVLDESPEFDRTALNRFVGAAIPLLTAPVIGMAMRAWWETGRSLWWPLAIGILGIAVLVGSFVANRFYQSGHLAECLLVTTYLLIATAAALAVPLPRGVNSLGAPQVAGAATAVLFLTLMTRGGPRKRHELASFAVITAIAVIAAAAAFGYGYQDWVPAGGIAFGLFIVTNAAKLTVAVARIALPPIPVPGETVDNEELLDPVATPEATSEETPTWQAIIASVPASAVRLTERSKLAKQLLIGYVTSGTLILAAGAIAVVVRGHFFVHSLVVAGLITTVCGFRSRLYAERWCAWALLAATVAIPTGLTAKLIIWYPHYAWLLLSVYLTVALVALVVVGSMAHVRRVSPVVKRTLELIDGAMIAAIIPMLLWITGVYDTVRNIRF
Atome Classification :
(20 SA)
-------------------------------------------------------------------.........10........20--------........30--.-.--.......40----.........50.......-------.60......-..70........80...------......90.-.......---------.100.......110.....----------------...-120.......----130..-.....140...---....150---.........160..-....---.170........180.......190.....-..200.......210.......220.......230...-----....240.......250-.........260.......------270-----.......280.---......290.-......300.......310......------------------.320......------.330......------.340...--------....350.--------.....------------.360-------------------.....------....370......---.380--........----390...-------....400-......-...410.......420.......430.....--..440.......450-----.........460......---.470.......480.......490.......500-------.......510-----------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------------------MSAPAVAAGPTAAGATAARPA--------
T
T
R
V
T
I
L
TG---R-
R
--
M
T
D
L
VLPA-----AV
P
M
E
T
YID
D
T
V
A
V
L
S
E
V
-------
L
EDT
P
A
D
V
L-GGFDFTAQ
G
V
W
A
F-ARP------GSPPLKL-D-QSLDDAG---------VVDG
S
L
L
T
L
V
S
VS-
R
T
E
R
Y
----------------
R
P
L
-
V
E
D
V
I
D
A
I
A
V----LDESP-EF
D
R
T
A
L
N
R
F
V
---
G
AA
I
P
-----
L
L
T
A
P
V
I
G
M
A
M
R
A
W
-
W
E
TG---RS
L
-
W
W
P
L
A
I
G
I
L
G
I
A
V
L
V
G
S
F
V
A
N
R
F
YQS-G
H
L
A
E
C
L
L
V
T
T
Y
L
L
I
A
T
A
A
A
L
AVPLPRG
V
N
SLGAP
Q
V
A
-----
G
A
A
T
A
V
L
F
L
T
L
MTRG---GP
R
K
R
H
E
L
A
S
F
A
V
I
T
A
I
A
V
------
I
A
A
-----
A
A
A
FGYG
Y
Q
DW---VPAGG
I
A
F
G
L
-
F
I
VTNAA
K
L
T
V
A
V
A
R
IALPPIPVPG------------------ETVD
N
E
ELLD------PVATPEATSE------ETP
T
W
Q
A
--------
I
I
A
SVP
A
S
--------
A
V
R
L
T
------------
E
R
---------------------
S
K
L
A
K
------
Q
L
L
I
G
YVTSG
T
L
I
---
L
AA---
G
A
I
A
V
V
VR----
G
H
F
F
V
H
-------
S
L
V
V
A
---
G
L
I
T
T
V
-
C
G
F
R
S
R
L
Y
A
E
R
W
C
A
W
A
L
L
A
A
T
V
AIPTG
L
T
A
K
--
L
I
I
WYP
H
Y
A
W
L
L
L
-------
S
V
Y
L
T
V
A
L
V
A
L
V
V
V
G
S
M
A
---
H
V
R
R
V
S
P
V
V
K
R
T
L
E
L
ID
G
A
M
I
A
A
I
I
P
M
L
L
W
I
T
G
V
-------
Y
D
T
V
R
NIRF------------------------------------------------------------
27
Fugue
81.38
20%
-110
* C4 *
5EY9
5
FAA32_MYCMM
A:
[3-626]
-------------------------------------------------YHNPFIVNG
K
I
R
F
P
E
NTN
L
V
R
H
V
E
K
W
A
R
V
R
G
D
K
L
A
Y
R
F
L
DFSTERD
G
V
E
R
D
I
L
W
S
E
---
F
-
S
--
A
R
N
R
A
V
G
A
-----
R
L
Q
Q
V
T
Q
P
G
D
R
I
A
I
L
C
P
Q
-------
N
L
D
Y
L
I
S
F
F
-
G
A
L
-
Y
S
G
R
I
A
V
P
L
-
F
D
P
------
A
E
H
V
G
R
L
-
H
-
A
V
L
D
D
C
T
PS
T
I
L
T
T
TD
S
A
E
G
V
R
K
F
I
R
S
R
S
-
A
K
E
R
P
----------------
R
V
I
A
V
D
A
V
P
T
E
V
A
S
----
T
W
Q
Q
P
-
N
E
L
T
T
A
Y
L
Q
Y
T
V
P
S
G
V
Q
I
T
-----
H
L
N
L
P
T
N
V
L
Q
V
L
N
A
-
L
E
G
Q
EG
D
R
G
V
S
W
L
P
F
F
H
D
M
G
L
I
T
V
L
L
A
S
V
L
--------
G
H
--
S
F
T
F
M
T
P
A
A
F
V
R
R
P
G
R
W
I
R
E
L
A
R
K
P
G
E
T
G
G
--
T
F
-----
S
A
A
P
N
F
A
F
E
H
A
A
M
R
G
---
V
P
R
D
D
E
P
P
L
D
L
S
N
V
K
G
I
L
N
GSEPVS
P
A
S
-----
M
R
K
F
F
K
A
F
E
P
Y
GLR
E
T
A
V
K
P
S
Y
G
L
-------
A
E
A
T
L
F
V
S
T
T
P
M
D
E
V
P
-
T
V
------------------
I
H
V
D
R
D
E
L
N
K
Q
R
F
V
E
V
A
A
D
A
P
N
A
V
A
Q
V
S
AGKV
G
V
D
E
W
A
V
--------
I
V
D
T
E
T
A
S
E
L
P
D
GQI
G
E
I
W
L
H
G
NNLGIGYWGK
E
E
E
---------------------
S
A
Q
T
F
------
R
N
I
L
K
S
R
V
P
E
S
H
A
---
E
G
A
---
P
D
D
G
L
W
V
R
TG
D
Y
G
T
Y
F
K
G
-------
H
L
Y
I
A
---
G
R
I
K
D
L
-
V
I
I
D
G
R
N
H
Y
P
Q
D
L
E
Y
T
A
Q
E
S
T
K
A
L
R
V
G
Y
V
A
A
--
F
S
V
P
A
N
Q
L
P
Q
K
V
F
D
DPHAGL
S
F
D
P
E
D
T
S
E
Q
L
V
I
V
G
E
R
A
A
GT
H
K
L
E
Y
Q
P
I
A
D
D
I
R
A
A
I
A
V
G
H
G
V
T
V
R
D
V
L
L
V
S
A
G
T
IPRTSSG
K
I
G
R
R
A
C
R
T
A
Y
I
D
GSLRSTVFA-----------------------------------------------
31
Fugue
79.62
19%
-105
- C3 -
4YU6
10
?
A:
[1-754]
NLIQ
E
D
R
L
A
E
A
L
K
E
R
GTINPASS
K
E
E
T
K
K
A
V
E
K
Y
I
E
K
K
QGDQANKEILPADTAKEAS
D
F
V
K
K
V
K
E
K
K
M
E
E
K
E
K
V
K
K
P
E
K
N
V
S
P
E
Q
K
P
E
--------
P
N
K
K
Q
-
L
N
G
---
Q
-
V
--
P
T
S
K
A
K
Q
A
-----
P
Y
K
G
S
V
R
T
D
K
V
L
V
L
L
V
E
F
SDYKHNN
I
D
Q
T
P
G
Y
M
Y
S
N
D
F
S
R
E
H
Y
Q
K
M
L
F
-
G
N
E
P
Y
T
L
FD
G
S
K
V
K
T
F
-
K
-
Q
Y
Y
E
E
Q
S
G
GSY-----
T
T
D
G
Y
V
T
E
W
L
T
V
P
G
K
A
S
D
Y
G
A
D
G
SSGHDNKGPKG
A
R
D
L
-
V
K
E
A
L
H
A
A
A
E
K
GLD
L
S
Q
F
D
-
Q
F
D
R
Y
D
T
N
S
D
G
---
N
Q
N
E
P
DGVID
H
L
M
V
I
H
A
G
V
G
Q
E
A
G
G
G
K
L
G
---
D
D
A
-
I
W
S
H
R
S
K
L
A
I
D
P
V
A
I
E
G
T
K
S
K
V
D
Y
F
G
-
G
K
V
----
A
A
H
D
Y
T
I
E
P
E
D
G
A
V
G
V
F
A
H
A
F
G
H
D
L
G
L
P
D
E
Y
DTKYT
G
T
G
S
P
V
E
A
W
S
L
M
S
G
G
SWT
G
K
I
A
G
T
E
P
T
S
F
S
P
Q
N
K
D
F
L
------
Q
K
N
MGGNW
A
K
I
L
E
V
D
Y
D
K
I
---
K
R
G
V
G
V
P
T
Y
I
D
Q
S
V
T
K
S
N
R
P
--
G
V
V
R
V
N
L
P
G
K
S
V
E
T
IKPEFGK
H
A
Y
Y
S
T
R
G
D
D
M
H
T
T
L
E
T
P
F
F
D
------
L
T
K
G
T
N
A
K
F
D
------
Y
K
A
N
Y
E
L
EAE
C
D
F
V
E
V
H
A
V
T
E
D
G
--------
T
K
T
L
I
------------
D
R
LGEKVVQGDKDTTDG
K
W
I
D
K
S
Y
D
L
S
Q
FKG
K
K
V
K
L
Q
F
D
Y
I
T
D
P
A
V
T
YK
G
F
A
M
---
D
H
V
N
V
T
V
D
----
G
Q
V
V
F
S
DDAEGQS
K
M
N
L
N
---
G
F
V
V
S
D
G
T
E
K
K
A
H
Y
Y
Y
L
E
W
R
N
Y
A
G
S
D
N
G
L
K
A
G
K
G
P
V
Y
N
T
G
L
V
V
W
Y
A
D
D
S
F
K
D
N
-------
W
V
G
V
H
P
G
E
G
F
L
G
V
V
D
S
-----
H
P
E
A
F
V
G
N
L
N
G
K
P
T
Y
G
N
T
G
M
Q
I
A
D
A
A
F
S
F
D
Q
T
P
A
-------
W
S
V
N
S
L
T
R
G
Q
F
N
Y
S
G
LQGVTTFDDSKVYSNNQIADA
G
R
K
V
P
KLG
L
K
F
Q
VV
G
Q
A
DDKS
A
G
A
V
W
I
K
R
H
H
HH
25
Fugue
78.72
18%
-138
* C3 *
4QLA
1
HYEP_BOMMO
A:
[19-442]
-------------------------------------------------------------------
L
D
L
E
E
W
W
G
P
P
E
L
K
Q
K
Q
D
T
S
I
K
--------
P
F
E
I
T
-------------------------------
F
S
E
T
M
V
K
E
L
K
E
R
-------
I
K
K
R
---------------------
R
P
------
F
A
P
P
L
--------
E
G
V
G
---------
F
----------------
K
Y
----------------
G
F
N
-
S
K
Q
L
D
S
W
L
K
Y
----
W
A
E
---
E
Y
P
F
A
E
R
Q
K
F
L
---
N
Q
Y
-
P
-----
H
F
K
T
N
I
Q
G
L
N
I
H
F
M
-
R
I
T
P
---
K
V
P
-
K
G
V
E
I
V
P
L
L
L
L
H
G
W
P
G
S
--
V
R
E
F
Y
E
A
I
P
H
L
T
A
V
S
K
D
R
N
F
A
L
E
I
I
A
P
S
L
--
P
G
Y
G
F
S
D
A
A
V
R
P
G
L
A
-----
A
A
E
V
A
V
I
F
K
N
L
M
A
R
L
---
G
Y
K
Q
------
Y
Y
V
Q
G
G
D
W
G
------
A
L
I
-----
G
S
A
M
A
T
F
F
P
K
E
---
I
I
G
F
H
S
N
M
A
L
-
T
L
S
P
A
A
T
F
L
E
F
V
G
A
L
--
F
P
S
L
I
V
E
P
------------------
E
L
---
A
N
R
L
Y
------
P
L
S
E
K
Y
S
T
L
L
------
E
E
L
G
Y
M
H
--------
I
Q
A
T
K
P
D
T
--------
V
G
I
G
L
------------
T
D
S
P
-------------------
A
G
L
L
A
------
Y
I
L
E
K
F
S
T
W
T
N
P
D
---
L
R
S
KED
G
G
L
S
Y
R
W
T
----
K
D
Q
L
I
D
-------
N
L
M
L
Y
W
S
T
K
S
I
V
T
S
-
M
R
L
Y
A
E
S
F
S
S
R
H
F
D
L
K
L
D
E
I
Q
V
Q
V
P
----------------
T
W
V
L
Q
-------
A
K
H
E
L
A
Y
Q
P
P
C
I
L
K
M
K
Y
----------
P
K
L
V
N
A
S
V
I
E
D
G
G
H
F
L
A
F
E
L
P
E
I
F
A
K
D
V
-------
L
K
A
I
G
E
F
R
K
L
K
N---------------------------------------------------------
1
PsiBlast_PDB
76.14
100%
-100
- C2 -
4KV2
-
?
A:
[21-109]
---------------------------------------------------------------------------------------
A
--------
T
T
R
V
T
I
L
T
G
---
R
-
R
--
M
T
D
L
V
L
P
A
-----
A
V
P
M
E
T
Y
I
D
D
T
V
A
V
L
S
E
V
-------
L
E
D
T
P
A
D
V
L
-
G
G
F
D
F
T
A
Q
G
V
W
A
F
-
A
R
P
------
G
S
P
P
L
K
L
-
D
-
Q
S
L
D
D
A
G
---------
V
V
D
G
S
L
L
T
L
V
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
76.08
98%
-99
- C2 -
4KV2
-
?
A:
[20-109]
--------------------------------------------------------------------------------------
M
A
--------
T
T
R
V
T
I
L
T
G
---
R
-
R
--
M
T
D
L
V
L
P
A
-----
A
V
P
M
E
T
Y
I
D
D
T
V
A
V
L
S
E
V
-------
L
E
D
T
P
A
D
V
L
-
G
G
F
D
F
T
A
Q
G
V
W
A
F
-
A
R
P
------
G
S
P
P
L
K
L
-
D
-
Q
S
L
D
D
A
G
---------
V
V
D
G
S
L
L
T
L
V
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
76.08
98%
-99
- C2 -
4KV2
-
?
A:
[20-109]
--------------------------------------------------------------------------------------
M
A
--------
T
T
R
V
T
I
L
T
G
---
R
-
R
--
M
T
D
L
V
L
P
A
-----
A
V
P
M
E
T
Y
I
D
D
T
V
A
V
L
S
E
V
-------
L
E
D
T
P
A
D
V
L
-
G
G
F
D
F
T
A
Q
G
V
W
A
F
-
A
R
P
------
G
S
P
P
L
K
L
-
D
-
Q
S
L
D
D
A
G
---------
V
V
D
G
S
L
L
T
L
V
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
74.25
100%
-112
- C2 -
4KV3
-
MALE_ECOLI
A:
[376-461]
--------------------------------------------------------------------------------------------------
R
V
T
I
L
T
G
---
R
-
R
--
M
T
D
L
V
L
P
A
-----
A
V
P
M
E
T
Y
I
D
D
T
V
A
V
L
S
E
V
-------
L
E
D
T
P
A
D
V
L
-
G
G
F
D
F
T
A
Q
G
V
W
A
F
-
A
R
P
------
G
S
P
P
L
K
L
-
D
-
Q
S
L
D
D
A
G
---------
V
V
D
G
S
L
L
T
L
V
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
67.35
15%
-102
* C1 *
3QQ5
-
?
A:
[-1-398]
--------------------------------------------------------------------
T
M
R
--------------
L
G
F
--------
R
R
Y
I
V
V
A
G
R
---
R
-
N
--
V
G
K
S
S
F
M
N
-----
A
L
V
G
T
D
P
V
Y
K
S
M
E
L
H
------------------------------------
P
------
I
G
P
V
T
L
V
-
D
T
P
G
L
D
D
V
G
---------
E
L
-
G
R
L
--------
R
V
E
K
A
----------------
R
R
V
-
F
Y
R
A
D
C
G
I
L
V
----
T
D
S
A
P
T
P
Y
E
D
D
V
V
N
L
F
K
---
E
M
E
I
P
-----
F
V
V
V
----
V
N
K
I
D
V
-
L
G
E
K
---
A
E
E
-
L
K
G
L
Y
E
S
R
Y
E
A
K
V
L
L
V
S
A
L
Q
K
K
G
F
D
-----------------
D
I
G
K
T
I
S
E
I
L
P
G
D
E
E
I
P
Y
L
G
D
L
I
-----
D
G
G
D
L
V
I
L
V
V
P
I
D
L
G
---
A
P
K
G
R
L
I
M
P
Q
V
H
A
I
R
E
A
L
D
------
R
E
A
----------------------------
I
-
A
L
V
V
K
E
R
E
L
R
Y
V
M
E
N
I
G
M
K
P
K
L
V
I
T
------------------
D
S
----
Q
V
A
M
------
K
V
A
S
D
V
P
E
D
V
------
E
L
T
T
F
S
I
--------
V
E
S
R
Y
R
G
D
--------
L
A
Y
F
V
------------
E
S
---------------------
V
R
K
I
E
------
E
L
E
D
G
----
D
T
V
V
---
I
M
E
---
G
-----
C
T
----
H
R
P
L
T
E
-------
D
I
-----------------
G
R
V
K
I
P
R
W
L
V
N
H
-------
T
G
A
Q
L
N
F
K
--
V
I
A
G
K
D
F
P
D
L
E
E
I
-------
E
N
A
K
L
I
I
H
C
G
G
C
I
L
N
R
S
A
---
M
M
R
R
V
R
M
A
K
R
L
G
I
P
M
T
N
Y
G
V
T
I
S
Y
L
------
H
G
V
-------
L
E
R
A
I
R
P
F
-------------------------------------------------------------
17
HHSearch
48.76
19%
-59
- C2 -
1YQB
-
UBQL3_HUMAN
A:
[16-95]
-----------------------------------------------------------------------------------
R
G
S
P
H
--------
L
I
K
V
T
V
K
T
P
---
K
-
D
--
K
E
D
F
S
V
T
D
-----
T
C
T
I
Q
Q
L
K
E
E
I
S
Q
R
F
K
------------
A
------------
H
P
D
Q
L
V
L
-
I
-
F
------
A
G
K
I
L
K
D
-
P
-
D
S
L
A
Q
C
G
---------
V
R
D
G
L
T
V
H
L
V
I
K
R
-
Q
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
47.76
20%
-46
- C2 -
1WX7
-
UBQL3_HUMAN
A:
[10-91]
---------------------------------------------------------------------------------
A
P
V
Q
D
P
H
--------
L
I
K
V
T
V
K
T
P
---
K
-
D
--
K
E
D
F
S
V
T
D
-----
T
C
T
I
Q
Q
L
K
E
E
I
S
Q
R
F
K
------------
A
------------
H
P
D
Q
L
V
L
-
I
-
F
------
A
G
K
I
L
K
D
-
P
-
D
S
L
A
Q
C
G
---------
V
R
D
G
L
T
V
H
L
V
I
K
R
-
Q
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
47.35
15%
-54
- C2 -
2BWF
2
?
A:
[5-75]
-------------------------------------------------------------------------------------------------
L
N
I
H
I
K
S
G
---
Q
-
D
--
K
W
E
V
N
V
A
P
-----
E
S
T
V
L
Q
F
K
E
A
I
N
K
A
N
G
------------
I
P
------------
V
A
N
Q
R
L
-
I
-
Y
------
S
G
K
I
L
K
D
-
D
-
Q
T
V
E
S
Y
H
---------
I
Q
D
G
H
S
V
H
L
V
K
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
47.12
17%
-46
* C2 *
1WXV
-
A:
[4-87]
-------------------------------------------------------------------------------------
G
S
S
--------
G
L
T
V
T
V
T
H
S
---
N
-
E
--
K
H
D
L
H
V
T
S
QQGSS
E
P
V
V
Q
D
L
A
Q
V
V
E
E
V
I
G
------------
V
------------
P
Q
S
F
Q
K
L
-
I
-
F
------
K
G
K
S
L
K
E
M
E
-
T
P
L
S
A
L
G
---------
I
Q
D
G
C
R
V
M
L
I
G
K
K
-
N
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
45.72
13%
-60
- C2 -
2L76
-
NF2IP_HUMAN
A:
[259-335]
-----------------------------------------------------------------------------------
P
E
T
P
R
--------
L
F
P
L
K
I
R
C
R
---
A
-
D
--
L
V
R
L
P
L
R
M
-----
S
E
P
L
Q
S
V
V
D
H
M
A
T
H
L
G
V
------------------------
S
P
S
R
I
L
L
-
L
-
F
------
G
E
T
E
L
S
P
-
T
-
A
T
P
R
T
L
K
---------
L
G
V
A
D
I
I
D
C
V
V
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
45.41
9%
-37
- C2 -
3TIX
1
SMT3_YEAST (first)
A:
[55-131]
--------------------------------------------------------------------------------------
E
T
--------
H
I
N
L
K
V
S
D
G
---
S
-
S
--
E
I
F
F
K
I
K
K
-----
T
T
P
L
R
R
L
M
E
A
F
A
K
R
Q
G
------------
K
------------
E
M
D
S
L
T
F
-
L
-
Y
------
D
G
I
E
I
Q
A
-
D
-
Q
T
P
E
D
L
D
---------
M
E
D
N
D
I
I
E
A
H
R
E
Q
-
I
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
45.31
10%
-33
- C2 -
1V86
-
A:
[4-90]
---------------------------------------------------------------------------
G
S
S
G
D
A
G
G
G
V
G
K
E
--------
L
V
D
L
K
I
I
W
N
---
K
-
T
--
K
H
D
V
K
V
P
L
-----
D
S
T
G
S
E
L
K
Q
K
I
H
S
I
T
G
------------
L
------------
P
P
A
M
Q
K
V
-
M
Y
K
-------
G
-
L
V
P
E
-
D
-
K
T
L
R
E
I
K
---------
V
T
S
G
A
K
I
M
V
V
G
S
T
-
I
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
44.86
19%
-43
- C2 -
2BPS
-
YUKD_BACSU
A:
[1-78]
---------------------------------------------------------------------------------------
S
--------
Y
I
D
I
T
I
D
L
K
HYN
G
-
S
--
V
F
D
L
R
L
S
D
-----
Y
H
P
V
K
K
V
I
D
I
A
W
Q
A
Q
S
V
------------
S
M
---------
P
P
R
E
G
H
W
I
R
V
V
N
------
K
D
K
V
F
S
G
-
E
-
C
K
L
S
D
C
G
---------
I
T
N
G
D
R
L
E
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
44.66
18%
-34
- C2 -
1J8C
-
UBQL2_HUMAN
A:
[26-103]
----------------------------------------------------------------------------------
A
P
A
E
P
K
--------
I
I
K
V
T
V
K
T
P
---
K
-
E
--
K
E
E
F
A
V
P
E
-----
N
S
S
V
Q
Q
F
K
E
A
I
S
K
R
F
K
------------
S
Q
-----------
T
D
-
Q
L
V
L
--
I
F
------
A
G
K
I
L
K
D
-
Q
-
D
T
L
I
Q
H
G
---------
I
H
D
G
L
T
V
H
L
V
I
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
44.57
14%
-39
- C2 -
3A4R
1
NF2IP_MOUSE
A:
[5-77]
--------------------------------------------------------------------------------------
S
Q
--------
E
L
R
L
R
V
Q
G
K
---
E
-
K
HQ
M
L
E
I
S
L
S
P
-----
D
S
P
L
K
V
L
M
S
H
Y
E
E
A
M
G
L
------------------------
S
G
H
K
L
S
F
-
F
-
F
------
D
G
T
K
L
S
G
-
K
-
E
L
P
A
D
L
G
---------
L
E
S
G
D
L
I
E
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
44.12
12%
-50
- C2 -
2JXX
-
A:
[20-96]
-----------------------------------------------------------------------------------
T
E
T
S
Q
--------
Q
L
Q
L
R
V
Q
G
K
---
E
-
K
HQ
T
L
E
V
S
L
S
R
-----
D
S
P
L
K
T
L
M
S
H
Y
E
E
A
M
G
------------
L
------------
S
G
R
K
L
S
F
--
F
F
------
D
G
T
K
L
S
G
-
R
-
E
L
P
A
D
L
G
---------
M
E
S
G
D
L
I
E
V
W
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
44.04
5%
-49
- C2 -
2IO1
-
SUMO3_HUMAN
B:
[15-91]
---------------------------------------------------------------------------------------
D
--------
H
I
N
L
K
V
A
G
Q
---
D
G
S
--
V
V
Q
F
K
I
K
R
-----
H
T
P
L
S
K
L
M
K
A
Y
C
E
R
Q
G
------------
L
------------
S
M
R
Q
I
R
F
-
R
-
F
------
D
G
Q
P
I
N
E
-
T
-
D
T
P
A
Q
L
E
---------
M
E
D
E
D
T
I
D
V
F
Q
Q
Q
-
T
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------