@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA0716: (2016-01-16 )
MNFQIVINNIQHIGYAELDVDLNASGIICIVGKNGVGKTTLIKAILNLKSADTFSRTASPGIFKANSSMRCTYGENSYEFSFDSDINDLNSRSPIPEELKSVIDVELPMPFGQRFNNYQNIMSADMDIRTALILGEYEVPVELISFLSDIYKTNKFNGLVEVSAKGGSYYCIPLDDDRYVREDHLSSGEFFLISLYRKIKGRSKFIVIDEIDISLDAAAQAHLIGWLRRFCTTEQVKVVFTTHSLALMRTLKDGELFYMEESEGKVSVIPSSYNYIKSVLFGFKGWDRYILTEDAMLKSLLEYVLANYCSGLFFSYQIIHVGGGSNVVDLMRQNSTEGFFSTPENVISVLDGDQAEYRYARRPNVYCIPFLSVEKAIFAEYKAGRFLPELAPDPRFDTPKNFCSAIGRDRHATEADIIKYLCDSYPTEVRRFAQTLSDFLS
Atome Classification :
(20 SA)
-------........-.---10...------.----....20.....-...30........40.......--.50.---..----.....60........70........80..--......90........100.......110.......120.......130......---.---140.......150.......160.......170.......180.........190.......200--.........210.......220.......230.......240.......250.-----------------......260.......-------270.......280......------------------.290.......300.......310.......320----.......-330.-......340.......350....-...360.......370.......380.......390.......400.......410.......----420.--------......430....-..------.440------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------M
N
F
Q
I
V
I
N-N---IQHIG------
Y
----
A
E
L
D
V
DLNAS
G
-
I
I
C
I
VGKNGV
G
K
T
T
L
I
K
A
I
L
NL--KSAD---TF----SRTASP
G
I
F
KANS
S
M
R
C
T
YGEN
S
Y
E
F
SFD--SDINDLNSRSP
I
P
E
E
L
K
S
V
IDVELPM
P
F
G
Q
R
F
N
N
Y
Q
N
I
M
SADM
D
I
R
T
A
L
I
LGEYE---V---
P
V
E
L
I
S
F
L
S
D
I
Y
KTNKFN
G
L
V
E
V
SAKGG
S
Y
Y
C
I
PLDDD
R
Y
V
--
R
E
DHLSSG
E
F
F
L
I
S
L
Y
R
K
IK----GR
S
K
F
I
V
I
D
E
I
DIS
L
D
A
A
A
Q
A
H
L
I
G
W
L
R
R
FCTT
E
Q
V
K
V
V
F
TT
H
S
L
A
L
M
R
TLKD-----------------G
E
L
F
Y
M
EESEG
K
V
S
V
I-------PS
S
Y
N
Y
I
K
S
V
L
F
GFKGW
D
R
------------------
Y
I
L
T
E
D
A
M
L
K
S
L
L
E
Y
V
L
A
N
Y
C
S
G
L
F
F
S
Y
Q
I
I
H
VG----GG
S
N
V
V
D
-
L
M
R
Q-NSTEGFFS
T
P
E
N
V
I
S
VLDGDQA
E
-
Y
R
YARRP
N
V
Y
C
I
P
F
L
S
V
E
K
A
I
F
A
E
YKAGRFLPELAPDPRFD
T
P
K
N
F
C
S
A
IGRDRHA
T
E
A
D
I
I
K
----
Y
L
C
D--------SY
P
T
E
V
R
R
F
A
Q
T
L
-
S
D
------
F
LS-------------------------------------------------------------------------------
29
Fugue
76.87
19%
-89
- C1 -
1E69
-
?
A:
[1-1164]
-----------
M
R
L
K
-
K
---
L
Y
L
K
G
------
F
KSFG
R
P
S
L
I
G
F
S
-
D
R
-
V
T
A
I
V
G
P
N
G
S
G
K
S
N
I
I
D
A
I
K
W
V
F
G
E
K
F
D
---
M
I
FAGS
E
N
L
P
P
A
G
S
A
Y
V
E
L
V
F
E
E
N
G
E
E
I
T
V
A
R
E
L
K
--
R
T
G
E
N
T
Y
Y
L
N
G
S
P
V
R
L
K
D
I
R
D
R
F
A
G
T
G
L
G
V
D
F
Y
S
I
V
G
-----
Q
G
Q
I
D
R
I
V
N
A
Y
Q
R
---
V
---
N
E
S
F
N
R
F
I
S
L
L
F
F
G
G
E
G
R
L
E
I
S
I
R
K
P
G
----------
R
R
D
Q
--
K
L
S
L
L
S
G
G
E
K
A
L
V
G
L
A
L
L
F
A
L
MEI
K
P
S
P
F
Y
V
L
D
E
V
D
S
P
L
D
D
Y
N
A
E
R
F
K
R
L
L
K
E
N
S
K
H
T
Q
F
I
V
I
--
T
H
N
K
I
V
M
E
A
A
D
-------------------
L
L
H
G
V
T
M
V
N
G
V
S
A
I
V
-------
P
V
E
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
64.77
16%
-77
- C1 -
1Z47
1
?
A:
[11-355]
-------
G
S
M
T
I
E
F
V
-
G
---
V
E
K
I
Y
PGGARS
V
----
R
G
V
S
F
Q
I
R
E
G
E
-
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
--
E
R
P
T
---
K
-----------
G
D
V
W
I
G
G
------------------------
K
R
V
T
D
L
P
P
Q
K
R
N
V
G
L
V
F
Q
N
Y
A
L
F
Q
H
M
T
V
Y
D
N
-
V
S
F
G
L
R
E
K
R
V
--------------------------
P
K
D
E
M
D
A
R
V
R
E
L
L
R
F
-----
M
R
L
E
S
Y
A
N
R
--
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
----
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
E
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
----------------------------
R
V
L
V
L
-------
H
-------------
E
G
N
V
E
------------------
Q
F
G
T
P
E
E
V
Y
E
K
P
G
T
L
F
V
A
S
F
I
G
E
S
--
N
V
W
T
R
A
V
Q
----
N
G
R
I
E
V
A
-
G
A
A
L
-
P
V
D
P
A
V
S
E
G
S
E
V
A
V
V
V
-------------
R
P
K
D
V
E
L
Q
P
A
S
E
R
E
A
H
A
Q
V
V
R
S
A
F
K
G
S
Y
S
A
C
W
I
R
T
K
D
G
E
V
W
E
V
H
V
P
S
A
D
R
H
R
W
S
P
---------------------
G
A
W
V
H
M
N
V
T
R
W
-
F
I
------
F
P
R
-------------------------------------------------------------------------------
28
Fugue
57.64
14%
-84
- C1 -
3TUZ
3
METN_ECOLI
H:
[23-362]
HMIKLSN
I
T
K
V
F
H
Q
G
-
T
---
R
T
I
Q
A
------
L
----
N
N
V
S
L
H
V
P
A
G
Q
-
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
--
E
R
P
T
---
E
G
----
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
K
A
R
R
Q
I
G
M
I
F
Q
--
H
--
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
E
L
D
-----
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
-------------------------------------------------
V
G
L
G
D
K
H
D
S
--
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
----
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
----------------------------
C
V
A
V
I
-------
S
N
G
-----------------------------------
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
--
T
L
H
L
D
----
I
P
E
D
Y
Q
E
-
R
L
Q
A
-
E
P
F
T
D
C
V
P
M
L
R
L
E
F
T
G
Q
S
V
D
A
P
L
-
L
S
E
T
A
R
R
F
N
V
N
N
N
I
I
S
A
Q
M
D
Y
A
G
G
V
K
F
G
I
M
L
T
E
M
H
G
T
-----------------
Q
Q
D
T
Q
A
A
I
A
----
W
L
Q
E
--------
H
H
V
K
V
E
V
-------------------------------------------------------------------------------------------------
30
Fugue
54.65
15%
-78
- C1 -
1OXS
23
?
C:
[1-352]
-MVRIIV
K
N
V
S
K
V
F
K
-
K
---
G
K
V
V
A
------
L
----
D
N
V
N
I
N
I
E
N
G
E
-
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
--
D
V
P
S
---
T
-----------
G
E
L
Y
F
D
----------------
D
--
R
L
V
A
S
N
G
K
L
I
V
P
P
E
D
R
K
----------
I
G
M
V
F
Q
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
A
F
P
L
T
N
M
K
---
M
---
S
-----------
K
E
E
I
R
K
R
V
E
E
V
A
K
I
------
L
D
I
H
H
V
L
N
H
--
F
P
R
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
----
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
------------------
R
V
G
V
L
V
K
--
G
K
L
V
Q
V
-------
G
K
P
E
D
L
Y
D
N
P
V
------
S
I
------------------
Q
V
A
S
L
---
I
G
E
I
N
E
L
E
G
K
V
T
N
E
G
V
V
I
G
S
L
R
F
P
V
S
----
V
S
S
D
R
A
I
-
I
G
I
R
----------
P
E
D
V
K
L
S
K
D
V
I
K
D
D
S
W
I
L
V
G
K
G
K
V
K
V
I
G
Y
Q
G
G
L
F
R
I
T
I
T
P
L
D
S
E
E
E
I
F
T
Y
S
D
H
P
I
H
S
G
E
E
V
L
V
Y
V
R
K
D
K
------------------------------
I
K
V
F
E
K
---------------------------------------------------------------------------------------------
7
PsiBlast_PDB
54.55
23%
-129
- C1 -
3C4J
3
?
A:
[147-231]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
L
K
D
K
A
H
A
--
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
----
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
-----------------
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
-------
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
------------------
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
54.18
18%
-94
- C1 -
2PJZ
5
?
A:
[1-261]
---M
I
Q
L
K
N
V
G
I
T
L
S
-
G
---
K
G
Y
E
R
------
F
----
S
L
E
N
I
N
L
E
V
N
G
E
K
V
I
I
L
G
P
N
G
S
G
K
T
T
L
L
R
A
I
S
G
L
--
L
P
---------------
Y
S
G
N
I
F
I
N
G
-------------------------------------
M
E
V
R
K
I
R
N
Y
I
R
Y
S
T
N
L
P
E
A
Y
E
I
G
V
T
V
N
D
I
V
Y
L
Y
E
E
L
---
K
---
G
L
D
R
D
L
F
L
E
M
L
K
A
L
K
L
G
E
E
I
L
R
----------------
R
K
L
--
Y
K
--
L
S
A
G
Q
S
V
L
V
R
T
S
L
A
L
A
----
S
Q
P
E
I
V
G
L
D
E
P
F
E
N
V
D
A
A
R
R
H
V
I
S
R
Y
I
K
E
Y
G
K
E
----
G
I
L
V
T
H
E
L
D
M
L
N
L
Y
K
E
Y
K
A
Y
F
LVGNRLQGPIS
V
S
E
L
L
E
S
S
I
V
E
G
E
R
N
D
A
-------
L
L
V
L
D
I
M
D
K
K
V
S
I
V
K
G
D
L
G
------------------
M
K
F
G
A
L
G
S
L
N
R
I
Y
G
I
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
53.11
23%
-128
- C1 -
2OLK
-
?
A:
[147-231]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
L
K
D
K
A
H
A
--
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
----
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
-----------------
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
-------
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
------------------
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
52.25
23%
-127
- C1 -
2Q0H
2
?
A:
[147-231]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
L
K
D
K
A
H
A
--
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
----
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
-----------------
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
-------
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
------------------
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
HHSearch
52.23
16%
-106
- C1 -
1V43
-
?
A:
[18-219]
---------
L
T
K
R
F
G
-
N
---
F
T
A
V
N
------
K
----
L
N
L
T
I
K
D
--
G
E
-
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
--
E
E
P
T
---
E
G
----
R
I
Y
---------------
F
G
D
R
D
V
T
Y
L
P
P
------
K
D
R
N
I
S
M
V
F
Q
--------
H
-------------------
M
T
V
Y
E
N
I
A
F
P
L
-----
K
KFP
K
D
E
I
D
K
R
V
R
W
A
--------
A
E
L
L
Q
I
E
E
----
L
----
L
N
R
Y
----
P
A
Q
L
S
G
G
Q
R
Q
R
V
A
V
A
R
A
I
V
----
V
E
P
D
V
L
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
A
M
R
A
E
I
K
K
L
Q
Q
K
L
K
V
T
T
I
Y
V
T
H
D
Q
V
E
A
M
T
M
G
D
------------------
R
I
A
V
M
N
R
G
Q
L
L
Q
I
G
S
-------
P
T
E
V
Y
L
R
P
N
S
V
F
V
A
T
F
I
G
A
------------------
P
E
M
N
I
L
E
V
S
V
G
D
G
Y
L
E
G
R
G
F
R
I
E
L
P
Q
M
D
L
L
K
D
Y
V
----
G
K
T
V
L
F
G
-
I
R
P
E
-
H
M
T
V
E
G
V
H
M
K
R
T
A
R
L
I
G
K
V
D
F
V
E
-
A
L
G
T
D
T
I
L
H
V
K
F
G
D
E
L
V
K
V
K
L
P
G
H
I
P
I
E
P
G
R
E
V
K
V
I
M
D
L
D
M
I
H
V
F
D
K
D
T
E
K
A
I
V
---------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
52.10
23%
-126
- C1 -
2OUK
-
?
A:
[147-231]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
L
K
D
K
A
H
A
--
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
----
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
-----------------
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
-------
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
------------------
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
HHSearch
52.05
17%
-111
- C1 -
3RLF
3
MALK_ECOLI
A:
[8-210]
--------
N
V
T
K
A
W
G
-
E
---
V
V
V
S
K
------
D
----
I
N
L
D
I
H
E
--
G
E
-
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
--
E
T
I
T
---
S
G
----
D
L
F
---------------
I
G
E
K
R
M
N
D
T
P
P
AE
R
G
V
G
M
V
------
F
Q
--
S
Y
A
L
Y
P
H
-------------------
L
S
V
A
E
N
M
S
F
G
L
K
L
---
A
GAK
K
E
V
I
N
Q
R
V
N
Q
V
--------
A
E
V
L
Q
L
A
H
----
L
----
L
D
R
K
----
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
----
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
------------------
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
-------
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
------------------
P
K
M
N
F
L
P
V
K
V
T
A
T
A
I
D
Q
V
Q
V
E
L
P
M
P
N
R
Q
Q
V
W
L
P
V
----
E
S
R
D
V
Q
V
-
G
A
N
M
-
S
L
G
I
R
P
E
H
L
L
P
S
D
I
A
D
V
I
L
E
G
E
V
-
Q
V
V
E
Q
L
G
N
E
T
Q
I
H
I
Q
I
P
S
I
R
Q
N
L
V
Y
R
Q
N
D
V
V
L
V
E
E
G
A
T
F
A
I
G
L
P
P
E
R
C
H
L
F
R
E
D
G
T
A
C
R
R
L
H
K
----
E
P
G
V
--------
A
-------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
51.25
23%
-129
- C1 -
2OLJ
3
?
A:
[147-231]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
L
K
D
K
A
H
A
--
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
----
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
-----------------
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
-------
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
------------------
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
51.22
23%
-122
- C1 -
3C41
2
?
J:
[126-210]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
L
K
D
K
A
H
A
--
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
----
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
-----------------
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
-------
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
------------------
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
50.64
16%
-99
- C1 -
3FVQ
3
FBPC_NEIG1
A:
[9-215]
--------
H
L
S
K
S
F
Q
-
N
---
T
P
V
L
N
------
D
----
I
S
L
S
L
D
P
--
G
E
-
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
--
E
Q
P
D
---
S
G
----
E
I
S
---------------
L
S
G
K
T
I
F
S
K
N
T
--
N
L
P
V
R
E
R
R
L
G
Y
L
V
Q
--
E
G
V
L
F
P
H
-------------------
L
T
V
Y
R
N
I
A
Y
G
L
G
N
---
G
KGR
T
A
Q
E
R
Q
R
I
E
A
M
--------
L
E
L
T
G
I
S
E
----
L
----
A
G
R
Y
----
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
----
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
------------------
R
I
A
V
M
K
Q
G
R
I
L
Q
T
A
S
-------
P
H
E
L
Y
R
Q
P
A
D
L
D
A
A
L
F
I
G
E
------------------
G
I
V
F
P
A
A
L
N
A
D
G
T
A
D
C
R
L
G
R
L
P
V
Q
S
G
A
P
A
G
T
R
G
T
----
L
L
I
R
P
E
Q
-
Y
S
L
H
-
P
H
S
A
P
A
A
S
I
H
A
V
V
L
K
T
T
P
K
A
R
H
T
-
E
I
S
L
R
A
G
Q
T
V
L
T
L
N
L
L
S
D
G
I
S
A
V
L
H
L
D
G
P
A
L
F
F
P
G
----------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
50.64
17%
-99
- C1 -
1Z47
1
?
A:
[19-222]
--------
G
V
E
K
I
Y
P
G
G
---
A
R
S
V
R
------
G
----
V
S
F
Q
I
R
E
--
G
E
-
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
--
E
R
P
T
---
K
G
----
D
V
---------------
W
I
G
G
K
R
V
T
D
L
P
P
------
Q
K
R
N
V
G
L
V
F
Q
--
N
Y
A
L
F
Q
H
-------------------
M
T
V
Y
D
N
V
S
F
G
L
R
E
---
K
RVP
K
D
E
M
D
A
R
V
R
E
L
--------
L
R
F
M
R
L
E
S
----
Y
----
A
N
R
F
----
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
----
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
E
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
------------------
R
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
-------
P
E
E
V
Y
E
K
P
G
T
L
F
V
A
S
F
I
G
E
------------------
S
N
V
W
T
R
A
V
Q
N
G
R
I
E
V
A
G
A
A
L
P
V
D
P
A
V
S
E
G
S
E
V
A
V
----
V
V
R
P
K
D
V
-
E
L
Q
P
-
A
S
E
R
E
A
H
A
Q
V
V
R
S
A
F
K
G
S
Y
S
A
C
W
-
I
R
T
K
D
G
E
V
W
E
V
H
V
P
S
A
D
R
H
R
W
S
P
G
A
W
V
H
M
N
V
T
R
W
F
I
F
P
R
------------------------------------------------------------------------------------------------------------------------------------------------
41
HHSearch
50.42
16%
-93
- C1 -
2IT1
-
?
A:
[8-210]
--------
N
I
V
K
K
F
G
-
N
---
F
T
A
L
N
------
N
----
I
N
L
K
I
K
D
--
G
E
-
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
--
Y
K
P
T
---
S
G
----
K
I
---------------
Y
F
D
E
K
D
V
T
E
L
P
P
------
K
D
R
N
V
G
L
V
F
---
Q
N
W
A
L
Y
P
------------------
H
M
T
V
Y
K
N
I
A
F
P
L
E
L
---
R
KAP
R
E
E
I
D
K
K
V
R
E
V
--------
A
K
M
L
H
I
D
K
----
L
----
L
N
R
Y
----
P
W
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
----
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
K
R
L
Q
K
E
L
G
I
T
T
V
Y
V
T
H
D
Q
A
E
A
L
A
M
A
D
------------------
R
I
A
V
I
R
E
G
E
I
L
Q
V
G
T
-------
P
D
E
V
Y
Y
K
P
K
Y
K
F
V
G
G
F
L
G
N
------------------
P
P
M
N
F
V
E
A
K
V
E
D
G
K
L
V
I
T
E
K
S
K
L
P
I
P
K
Q
Y
V
E
I
V
K
----
E
T
G
I
T
E
V
-
I
I
G
F
-
R
P
H
D
A
E
I
V
K
G
E
G
E
G
I
V
G
E
V
Y
S
F
E
-
P
L
G
R
E
Q
I
V
T
V
S
V
N
D
S
I
V
K
V
F
A
P
E
G
E
H
F
S
F
G
E
K
V
T
I
K
V
K
E
E
L
L
V
L
F
D
K
K
T
E
K
A
L
E
F
S
K
L
-----------------------------------------------------------------------------------------------------------------------------
43
HHSearch
49.89
15%
-99
- C1 -
2YYZ
3
?
A:
[8-210]
--------
N
L
K
K
Y
F
G
-
K
---
V
K
A
V
D
------
G
----
V
S
F
E
V
K
D
--
G
E
-
F
V
A
L
L
G
P
S
G
C
G
K
T
T
T
L
L
M
L
A
G
I
--
Y
K
P
T
---
S
G
----
E
I
---------------
Y
F
D
D
V
L
V
N
D
I
P
P
------
K
Y
R
E
V
G
M
V
F
Q
--
N
Y
A
L
Y
P
H
-------------------
M
T
V
F
E
N
I
A
F
P
L
R
A
RRI
S
---
K
D
E
V
E
K
R
V
V
E
I
--------
A
R
K
L
L
I
D
N
----
L
----
L
D
R
K
----
P
T
Q
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
----
K
Q
P
K
V
L
L
F
D
E
P
L
S
N
L
D
A
N
L
R
M
I
M
R
A
E
I
K
H
L
Q
Q
E
L
G
I
T
S
V
Y
V
T
H
D
Q
A
E
A
M
T
M
A
S
------------------
R
I
A
V
F
N
Q
G
K
L
V
Q
Y
G
T
-------
P
D
E
V
Y
D
S
P
K
N
M
F
V
A
S
F
I
G
N
------------------
P
P
T
N
F
L
R
D
F
S
V
S
V
E
N
K
Q
T
I
L
K
R
D
D
V
I
I
K
L
P
E
P
V
D
----
V
K
L
K
E
V
V
-
V
G
I
R
-
P
E
H
C
R
I
S
R
E
R
V
E
N
S
I
P
G
V
V
Y
V
V
E
-
P
L
G
R
D
I
I
V
N
V
K
T
E
K
G
E
I
I
K
V
F
G
D
T
G
K
A
P
Q
P
G
E
N
V
F
L
V
P
D
L
R
K
I
H
L
F
N
P
E
T
E
E
T
I
L
--------------------------------------------------------------------------------------------------------------------------------
52
HHSearch
49.22
17%
-155
- C1 -
3BK7
-
?
A:
[470-547]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
L
S
G
G
E
L
Q
R
V
A
I
A
A
T
L
L
----
R
D
A
D
I
Y
L
L
D
E
P
S
A
Y
L
D
V
E
Q
R
L
A
V
S
R
A
I
R
H
L
M
E
K
N
E
K
T
A
L
V
V
E
H
D
V
L
M
I
D
Y
V
S
D
------------------
R
L
I
V
F
E
G
E
P
G
R
H
G
R
A
-------
L
P
P
M
G
M
R
E
G
M
N
R
F
L
A
S
V
G
I
------------------
T
F
R
R
D
P
D
S
G
R
P
R
A
N
K
E
G
S
V
K
D
R
E
Q
K
A
R
G
E
Y
Y
Y
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
HHSearch
49.20
18%
-80
- C1 -
3WMG
1
?
A:
[355-568]
--------
N
V
H
F
R
Y
P
-
T
RMN
V
E
V
L
R
------
G
----
I
S
L
T
I
P
N
--
G
K
-
T
V
A
I
V
G
G
S
G
A
G
K
S
T
I
I
Q
L
L
M
R
F
--
Y
D
I
E
PQG
G
G
-------------------
L
L
L
F
D
G
T
P
A
W
N
Y
D
----
F
H
A
L
R
S
Q
I
G
L
V
S
---
Q
E
P
V
L
F
S
G
T
I
R
D
N
I
L
Y
G
K
R
D
A
---------------------
T
---
D
E
E
V
I
Q
A
L
R
------------
E
A
N
A
Y
S
F
V
-
M
A
L
P
D
G
L
D
T
E
V
G
E
R
G
L
A
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
I
L
----
K
H
P
T
L
L
C
L
D
E
S
T
S
A
L
D
A
E
S
E
A
L
V
Q
E
A
L
D
R
M
M
A
S
D
G
V
T
S
V
V
I
A
H
R
L
S
T
V
A
R
A
D
-------------------
L
I
L
V
M
Q
D
G
V
V
V
E
Q
G
N
-------
H
S
E
L
M
A
L
G
P
S
G
F
Y
Y
Q
L
V
E
K
------------------
Q
L
A
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
47.26
17%
-75
- C1 -
1YQT
4
?
A:
[24-538]
-------
E
E
D
C
V
H
R
Y
-
G
---
V
N
A
F
V
------
L
----
Y
R
L
P
--
V
V
K
E
G
M
V
V
G
I
V
G
P
N
G
T
G
K
S
T
A
V
K
I
L
A
G
Q
--
L
I
P
N
------------------------------
L
C
G
D
N
D
S
W
--
D
G
V
I
R
A
F
R
G
N
E
L
Q
N
Y
F
E
K
L
K
N
G
E
I
R
P
V
V
K
P
Q
Y
V
D
L
I
P
K
A
V
K
G
K
V
I
E
L
L
K
K
A
D
E
T
G
---
K
---
L
E
E
V
V
K
A
L
E
-----------------------
L
E
N
V
L
E
R
E
I
--
Q
H
--
L
S
G
G
E
L
Q
R
V
A
I
A
A
A
L
L
----
R
N
A
T
F
Y
F
F
D
E
P
S
S
Y
L
D
I
R
Q
R
L
N
A
A
R
A
I
R
R
L
S
E
-
E
G
K
S
V
L
V
V
E
H
D
L
A
V
L
D
Y
L
S
D
------------------
I
I
H
V
V
Y
G
E
P
G
V
Y
G
I
F
S
QPKG
T
R
N
G
I
N
E
F
L
R
G
Y
L
K
D
E
N
V
R
F
R
P
Y
E
I
K
FTKTGERVE
I
E
R
E
T
L
V
T
Y
P
R
L
V
K
D
Y
G
S
F
R
L
E
V
E
P
G
E
I
K
K
G
E
V
I
G
I
V
G
P
N
GI
G
K
T
T
F
V
K
M
L
A
G
V
E
E
P
T
E
G
K
I
E
W
D
L
T
V
A
Y
K
P
Q
Y
I
K
A
D
-
Y
E
G
----
T
V
Y
E
L
L
S
K
I
D
A
S
K
L
N
S
N
F
Y
K
T
E
L
L
K
P
L
G
I
I
D
L
Y
D
R
E
V
N
E
L
S
G
G
E
L
Q
R
V
A
I
A
A
T
L
L
R
DAD
I
Y
L
L
D
EPSAYLD
V
E
Q
R
L
A
V
S
R
A
I
R
H
L
M
E
K
N
E
K
T
A
L
V
V
E
HD
V
L
M
I
D
Y
V
SD
R
L
M
V
F
E
G
EPGK
Y
G
R
A
L
P
PMG
M
R
E
G
M
N
R
F
L
A
S
I
G
I
T
F
R
R
D
PDTG
R
P
R
A
N
K
EGS
V
K
D
R
E
Q
K
E
K
GEYYYIA