@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA3075: (2016-02-13 )
MIRLFCSLLLALLCVSAHASFSASVDRARLTEGESVELTLESDDPTLFGKPDLSPLDALFEVLGTRQVNRLATQNGRAQATTRWIVTLLPKQSGYVAIPPISLGASSTQPIRLHVLEARDRAKSSKLAPVFIDASVDQETVYVQAQAILTLRIYHSVSLYDDSSLTPLAMNDAKVEQLGEARTYEKEINGIRHGVIEVRYAIFPQKSGTLEIPAQAFSATLVDRGSDDYNPFGPRPGRQMRVTSPSIPLQVRPKPADYPADAPWMPARALSISESWSPQPEQAQVGESLTRNVLLKVEGLSGTQLPPLPLPDVQGLRRYPDQPQLADQSTDQGLIGSREEREALVPEQAGRIELPALEVVWWNTREDRLERTSLPPRTLEVAAAPQAEAEPPAAALPLGERLEPTLWPWQLATAVLALTTLLGFGLWWRARQLPAVIRAAANGPSSRSLLDELRRACLANDPQATRQALDAWARQQPDTLADMAARFVPLSDALDGLNGALYSESGHSWQGEDLWRAIRALPTTEQAPAGAVDNGGLPPLYPR
Atome Classification :
(20 SA)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10..-----......20........30........40......----..50........--60........70......--..80.....---------...90........100-..-------......110....-...120...-....130.......140-----........150.......--160........170..-.....180...----..-..190.......200..-----..-----...210.--...---------..---------..220.......230...--....240------........250.......260.......270.......280.......290....-.-----..300...----------....310.......320.......330..-.....340.......350.-.----.....360....---....370--.......-----.380---.......390.......400--.......410......-.420..-----.....430..---....--.440.......--450.--....---..460.......470.......480..------------.....490.......500...-......510--...------------------.....520........530.......540.-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
R
L
F
C
S
L
L
L
A
L
L
-----
C
V
S
AHASFSASVDRARLTEG
E
S
V
E
L
T
LESDDPTL----FGKPDL
S
P
L
D
A
L
--
F
E
V
L
G
T
R
Q
V
N
R
L
ATQNGR--A
Q
A
T
T
R
W
I
V
---------
T
L
LPKQSG
Y
V
AIPPI--SL-------GASSTQ
P
I
R
L
H
V
L
-EARDRAKSS-KL
A
P
V
F
I
DASVDQ
E
T
V
------
Y
V
Q
A
Q
A
I
L
T
L
R
I
Y
H
S
V
S
L--YD-DSSLTPLAM
N
D
A
K
-
V
E
Q
LGEA
R
T
Y
E
----
K
E
-
I
N
G
I
R
H
G
V
I
E
V
R
Y
A
I
FP-----QK-----SG
T
L
-
E
I--
P
A
Q
---------
A
F
---------
S
A
T
L
VDRGSDDYNPFGPR--PG
R
Q
M
R
-------VTSPSI
P
L
Q
VRPKPADYPADAPWMP
A
R
A
LSISESWSPQ
P
E
Q
A
Q
V
G
E
S
L
T
R
N
V
L
L
K
-
V
-----EGLSGTQL----------PPLPLP
D
V
Q
G
L
RRYPDQPQLADQSTDQGL-IG
S
R
E
E
R
E
ALVPEQAG
R
I
E-L----
P
A
L
E
V
V
W
-WNT
R
---
E
D
R
L
ER---TSLPPR
T
-----
L
E
V
A---AAPQAEAEPPAAALPLGERL--EPTL
W
P
W
Q
L
A
T
A
V
L
A
L
-
T
T
L
L
G
F
-----
G
L
W
W
R
A
R
Q
L
P
---
A
V
I
R
--
A
AANGP
S
S
R
S
L
--
L
D
E
L
--
R
R
A
C---LAN
D
P
Q
A
T
R
Q
A
L
D
A
W
A
RQQP
D
T
L
A
D
M
A
------------
A
R
FV
P
L
S
D
A
L
D
GLN
G
A
--
L
YS-ESGHSWQ
G
---
E
D
L
------------------
W
R
A
I
R
AL-PTTEQAPAGAVDNGGLPPLYPR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
86.41
18%
-34
- C2 -
2B39
1
CO3_BOVIN
A:
[30-1661]
TPN
I
L
R
L
E
S
E
E
T
V
V
L
E
A
H
GGQG
T
I
Q
V
S
V
T
V
H
D
FPAKKQVLSN
E
N
T
Q
L
N
S
NNGY
L
S
T
V
T
I
K
I
P
ASKELKSDK
G
H
K
F
V
T
V
VATFGN
V
Q
V
E
K
VVLISLQS
G
Y
L
F
I
Q
T
DKTIYTPG
S
T
V
L
Y
R
V
F
T
V
D
HKLLPVG
Q
T
V
F
I
T
I
E
T
PD
G
I
P
V
K
R
D
S
K
S
SQNQF
G
I
L
T
L
S
W
NIPE
L
V
N
M
G
V
W
K
I
K
A
Y
Y
EDSPQ
Q
V
F
S
A
E
F
E
V
K
E
Y
VLPS
F
E
V
Q
L
E
P
EEKFYYIDDPDGLKV
N
I
I
A
R
F
LYGE
Q
V
D
G
T
A
F
V
I
F
G
V
Q
D
GDRRISLTHSLTRVPINDG
N
G
E
A
I
L
K
RQVLLNGVQPSRADALVG
K
S
I
Y
V
S
A
T
V
I
L
QSG
S
D
M
V
E
A
E
R
T
GIPIVTSP
Y
Q
I
H
F
T
KTP
K
F
F
K
P
A
M
P
F
D
L
M
V
Y
V
T
N
PDGSPARHIPVVTQGS
N
V
Q
S
L
T
QDDGVAK
L
S
I
N
T
Q
NKRDPL
T
I
T
V
R
T
KKDNIPEG
R
Q
A
T
R
T
M
Q
A
L
P
Y
N
T
QGNSNN
Y
L
H
L
S
V
PRVELKPG
E
T
L
N
V
N
F
H
L
R
T
D
P
GEQAKIR
Y
Y
T
Y
M
I
M
N
KGKLL
K
V
G
R
Q
Y
R
E
P
GQD
L
V
V
L
P
L
T
ITSDFIP
S
F
R
L
V
A
Y
Y
TLINAKGQREVV
A
D
S
V
W
V
D
V
KDSCMG
T
L
V
V
K
N
GGKEEKHHRPG
Q
Q
I
T
L
K
I
E
A
D
Q
G
A
R
V
G
L
V
A
V
D
K
G
V
F
V
LNKKNKLT
Q
R
K
I
W
D
V
V
EKADIGCTPGSGRN
Y
A
G
V
F
T
D
A
G
L
T
L
K
T
SQGLETQQRADPQCPQSV
Q
L
M
E
K
R
M
D
K
A
G
Q
Y
SS
D
L
R
K
C
C
E
D
G
M
RDN
P
M
K
F
P
C
Q
R
R
A
Q
F
I
LQG
D
A
C
V
K
A
F
L
D
C
C
E
Y
I
T
Q
L
R
Q
Q
H
S
R
D
G
A
L
-----
D
D
D
I
----
I
P
E
E
D
I
I
S
R
S
Q
F
--
P
E
S
W
L
W
T
V
I
E
D
L
-
K
Q
A
D
K
--
N
G
I
S
T
K
L
M
N
---------
V
F
L
K
D
S
I
T
T
W
E
I
L
A
V
--
S
L
S
DKK---
G
I
C
V
A
D
P
Y
E
V
T
V
M
-
Q
------------
D
F
F
I
D
L
R
L
P
Y
-
S
V
------
V
R
N
E
Q
V
E
I
R
A
I
L
Y
N
Y
R
E
A
--
E
N
-
L
K
V
R
V
E
L
L
Y
N
P
A
F
-
C
S
L
A
T
A
K
K
R
H
Q
----
Q
T
-
I
T
I
P
A
R
S
S
V
A
V
P
Y
V
I
V
P
-----
L
K
-----
I
G
L
H
-
E
V
--
E
V
K
---------
A
A
---------
V
----------
Y
N
H
F
I
S
-----------------
D
G
V
K
K
T
L
K
V
V
P
E
G
-----------
V
R
V
N
K
T
V
A
V
R
T
L
N
P
E
H
L
G
Q
G
G
V
Q
R
E
E
V
-------------
P
A
A
D
L
----------
S
D
-
Q
V
P
D
T
E
S
E
T
K
I
L
L
Q
G
T
P
V
A
Q
M
T
E
D
A
I
-
D
G
E
R
L
K
H
L
I
Q
T
P
S
G
C
G
E
Q
N
-
M
IGM
T
P
T
V
I
A
V
H
-
Y
L
D
S
---
T
D
Q
W
E
K
---
F
G
L
E
K
R
Q
E
S
L
E
L
I
R
K
G
---
Y
T
Q
Q
L
A
F
R
Q
K
S
S
A
Y
A
A
F
Q
Y
R
--
P
P
S
T
W
L
T
A
Y
V
V
K
V
F
A
L
A
A
N
L
I
A
I
-----
D
---
S
K
D
L
C
E
---
T
V
K
W
--
L
I
L
E
K
Q
K
P
D
G
I
--
F
Q
E
------------
D
G
P
V
I
H
Q
E
M
I
G
G
F
R
D
T
R
E
K
D
V
S
L
T
A
------------
F
V
L
I
A
L
H
E
A
K
D
I
C
E
A
Q
--
V
N
S
L
G
R
S
I
A
K
A
G
---
D
F
L
------------------
E
N
H
Y
R
E
L
-
R
R
P
Y
T
V
A
I
A
A
Y
A
L
A
L
L
G
K
L
E
G
D
R
L
T
K
F
L
N
T
AKEKN
R
W
E
E
P
NQ
K
L
Y
N
V
E
A
T
S
Y
A
L
L
A
L
L
A
R
KDYDTT
P
P
V
V
R
W
L
N
E
QRYYGGGYGST
Q
A
T
F
M
V
F
Q
A
L
A
Q
Y
Q
K
D
VPDHKE
L
N
L
D
V
S
I
Q
L
PSRNS
A
V
R
H
R
I
L
WESASL
L
R
S
E
E
T
KEN
E
R
F
T
V
K
A
E
G
K
G
Q
G
T
L
S
V
V
T
V
Y
H
A
K
L
KGKVSCKK
F
D
L
R
V
S
I
R
P
A
P
ETVKKPQDAK
G
S
M
I
L
D
I
C
T
K
Y
LGDQDA
T
M
S
I
L
D
I
S
M
M
TGFSPD
V
E
D
L
K
T
L
S
TGVDRYIS
K
Y
E
M
N
R
DSNKN
T
L
I
I
Y
L
DKVSHT
V
E
D
C
L
S
F
K
V
H
Q
YFNVGL
I
Q
P
G
A
V
K
V
Y
S
YYNLDE
T
C
I
R
F
Y
H
P
D
KEDGMLSKLCHK
D
T
C
R
C
A
EENCFT
L
E
D
R
L
D
K
A
C
EPGVDYVYKTRLI
Q
K
K
L
E
DDFDEY
I
M
V
IENIIKSGSD
E
V
Q
V
K
Q
E
R
K
F
I
S
H
IKCREALKLKEG
A
H
Y
L
V
W
G
V
SSDLWGEKP
K
I
S
Y
I
IGKD
T
W
V
E
LWPEAEECQD
E
E
N
Q
K
Q
C
E
D
L
A
N
F
T
E
N
M
V
V
FGCPN
27
Fugue
79.22
19%
-22
- C3 -
4JY3
7
?
A:
[10-379]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
R
R
A
E
V
A
G
G
-------------------------
G
F
A
G
L
--
T
A
A
I
A
L
K
Q
----------------
N
G
W
D
V
---------
R
L
H
------------------------------------------
E
K
S
S
-
E
L
R
A
F
-------
G
A
G
I
------
Y
L
W
H
N
G
L
R
V
L
E
G
L
G
A
L
D
D
--
V
L
-
Q
G
S
H
T
P
-----
P
T
-
Y
E
T
W
M
H
N
K
S
V
S
----
K
E
T
F
N
G
L
P
W
R
I
M
T
-----------------------------
R
S
---------
H
L
---------
H
D
A
L
V
N
R
A
R
A
--
L
G
V
D
I
S
--
V
N
S
E
A
V
-------
A
A
D
P
V
G
R
L
T
L
Q
T
--------------------------------
G
E
V
L
E
A
D
L
I
V
G
-
A
-----
D
G
V
G
S
----------------------
K
V
R
D
S
I
G
F
K
Q
D
R
W
V
S
K
D
-
G
L
-
I
R
L
I
V
P
R
M
---
K
K
E
L
G
H
G
E
-
W
----
D
N
T
I
D
M
W
N
F
W
P
R
---
V
Q
R
I
L
Y
---
S
P
C
N
E
N
E
-----
L
Y
L
G
---
L
M
A
P
A
-
A
D
P
R
G
S
S
V
P
I
D
L
E
V
--
W
V
E
M
F
P
F
L
E
P
C
L
I
E
A
A
-
K
L
K
T
A
R
-----
Y
D
K
Y
E
T
T
K
L
D
---
S
W
T
R
GK
V
A
L
V
G
D
A
A
H
A
M
--
C
P
A
L
AQ
G
A
G
C
---
A
M
V
N
A
F
S
L
S
Q
D
L
E
E
-
G
S
S
V
E
D
A
L
V
A
W
E
------------
T
R
I
R
P
I
T
D
R
C
Q
A
L
S
G
D
--
Y
A
A
-
N
--
R
S
L
S
K
---
G
N
M
------------------
F
--------
T
P
A
A
L
E
A
A
R
Y
D
P
L
R
R
V
Y
S
W
P
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
77.36
17%
-24
- C3 -
4S3Q
7
?
A:
[2-691]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ES
K
R
L
D
N
A
A
L
A
A
GISP
N
Y
I
N
AHG
K
P
Q
S
I
S
A
E
T
K
R
R
L
L
D
A
M
H
Q
T
P
-----
V
P
N
V
M
V
Y
T
S
G
K
K
M
P
M
V
V
E
G
S
G
E
Y
S
W
L
L
T
T
E
E
G
T
Q
----
Y
K
G
H
V
T
G
G
K
A
F
N
--
L
P
T
K
L
P
E
G
Y
H
T
L
T
L
T
Q
D
D
--
Q
R
A
H
C
R
V
I
V
A
P
KRCYEP
Q
A
L
L
N
K
Q
K
L
W
G
A
C
V
Q
L
--
Y
T
LRSEKNW
G
I
G
D
F
G
D
L
K
A
M
L
V
-
D
V
A
K
R
G
G
S
F
I
G
L
N
P
I
H
A
L
Y
P
A
N
P
E
S
A
SPYSPS
S
R
R
W
L
N
V
I
Y
I
D
V
N
A
V
E
D
F
--
H
L
-
S
E
E
A
Q
A
W
W
Q
L
P
T
T
-
Q
Q
T
L
Q
Q
A
R
D
A
D
WVD
Y
S
T
-
V
T
A
L
K
M
T
A
L
R
M
A
W
K
G
F
A
Q
RDD
E
Q
M
-----
A
A
F
R
-
Q
F
--
V
A
E
Q
G
D
S
L
F
W
Q
A
A
F
---------
D
A
L
H
A
Q
Q
V
K
E
D
E
M
R
W
G
W
P
AW
P
E
M
Y
Q
N
-------
V
D
S
P
E
V
R
Q
F
C
E
E
H
R
D
D
V
D
F
Y
L
-
W
L
Q
W
L
A
Y
S
Q
F
A
A
C
W
E
I
S
Q
G
Y
E
M
P
I
G
L
Y
R
D
L
A
V
G
-
V
AEGG
A
E
T
W
C
D
R
E
L
YCLK
A
S
V
G
A
P
P
D
I
L
G
P
L
G
Q
N
W
G
L
P
P
M
D
P
H
I
I
T
A
R
A
Y
E
P
F
-
I
E
L
L
R
A
N
M
Q
N
C
G
--
A
L
R
I
D
H
V
----
M
S
M
L
R
L
W
-
W
I
P
Y
---
G
E
T
A
D
Q
G
A
Y
V
H
Y
P
V
D
D
-----
L
L
S
I
---
L
A
L
E
S
K
R
H
R
---
C
M
V
I
G
E
D
L
GT
V
P
V
E
I
V
G
K
L
R
S
S
G
V
Y
S
-
Y
K
V
L
Y
F
ENDHE
K
T
F
R
A
P
K
A
Y
P
EQ
S
M
A
V
A
--
A
T
H
D
L
P
T
L
R
G
Y
W
E
C
G
D
L
--
T
L
G
K
T
L
G
L
Y
P
D
E
V
V
L
R
G
L
Y
Q
D
R
E
L
A
K
Q
G
L
L
D
A
L
H
K
Y
GCLPKRAGHK
A
S
L
M
S
M
T
P
T
L
N
R
G
L
Q
R
--
Y
I
A
-
D
S
N
S
A
L
L
G
L
Q
P
E
D
W
L
DMAEPVNIPGTSYQYKN
W
R
--
R
K
L
S
A
T
L
E
S
M
F
A
D
D
G
V
N
K
L
L
K
D
L
D
R
R
R
R
S
AH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
72.94
16%
-11
- C3 -
1IOK
-
CH60_PARDE
A:
[2-526]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A
A
K
E
V
K
F
N
S
D
A
R
D
R
-----
M
L
K
G
V
N
I
L
A
D
A
V
K
V
T
L
G
P
K
G
R
N
V
V
I
D
K
S
F
G
A
P
R
I
T
KD
G
V
S
V
A
K
E
I
E
L
S
D
K
--
F
E
N
M
G
A
Q
M
V
R
E
V
A
S
R
T
N
D
--
E
A
G
D
----------------------------------------
G
T
T
T
A
T
V
L
A
Q
A
I
V
-
R
E
G
L
K
A
V
A
A
-
G
M
N
P
M
D
L
K
R
G
I
D
V
A
T
A
------
K
V
V
E
A
I
K
-----
S
A
A
R
P
V
--
N
D
-
S
S
E
V
A
Q
V
G
T
I
S
A
N
G
E
S
F
I
G
Q
Q
I
A
E
A
----
M
Q
-
R
V
G
-
N
E
G
V
I
T
V
-----------
E
E
-----
N
K
G
M
-
E
T
--
E
V
E
---------
V
V
---------
E
G
M
Q
F
D
R
G
Y
L
S
P
Y
F
V
T
N
A
--
D
K
M
I
A
E
-------
L
E
D
A
Y
I
L
L
H
E
K
K
L
S
S
L
Q
P
Q
K
P
L
L
I
V
A
E
D
V
E
I
A
A
V
K
A
P
-------
G
F
G
D
R
R
K
A
M
L
Q
D
I
-----
A
I
L
T
G
G
I
D
----------
M
L
G
R
A
K
K
V
S
I
N
K
---------
D
N
T
T
I
V
D
G
-
A
G
E
K
A
E
I
E
A
R
V
S
Q
I
R
Q
Q
I
E
----------------
E
T
---
T
S
D
Y
D
R
---
E
K
L
Q
E
R
V
-----
A
K
L
A
G
G
V
A
V
I
R
V
G
G
M
T
E
I
E
V
K
E
R
K
D
R
V
--
D
D
A
L
---
N
A
T
R
A
A
V
Q
E
-
G
I
V
V
G
G
-----
G
--------
V
---
A
L
V
Q
--
G
A
K
V
L
E
G
L
S
G
A
---
N
S
D
--
Q
D
A
G
---
I
A
I
I
R
R
A
L
E
A
P
M
R
Q
I
A
E
N
A
G
V
D
G
A
V
V
A
------------
G
K
V
R
E
S
S
D
K
A
F
G
F
N
A
Q
TE
E
Y
G
-
D
M
F
K
F
G
V
I
---
D
P
A
------------------
K
V
V
R
T
A
L
-
E
D
A
A
S
V
A
G
L
L
I
T
T
E
A
M
I
A
E
K
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
67.83
18%
-3
- C3 -
4HNE
1
P4K2A_HUMAN
A:
[2-384]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
G
S
P
E
F
A
A
Q
A
Q
--
A
L
-
A
A
Q
A
A
A
A
A
H
A
A
Q
A
-
H
R
E
R
N
E
F
P
E
D
P
----
E
F
-
E
A
V
V
R
Q
A
E
L
A
I
E
R
C
I
F
P
-----
E
R
IYQGS
S
G
S
Y
-
F
V
K
D
P
Q
G
---------
R
I
---------
I
A
V
F
K
P
K
N
E
E
P
Y
G
H
L
N
P
K
--
W
T
K
W
L
Q
KFGRDCL
V
L
N
Q
G
Y
L
S
E
A
G
A
S
L
V
D
Q
K
L
E
L
N
I
V
P
R
T
K
V
V
Y
L
A
S
E
T
F
N
Y
S
A
I
D
R
V
K
S
R
G
K
R
L
A
L
R
---------
F
N
R
I
G
L
----------
P
P
K
V
G
S
F
Q
L
F
V
E
G
Y
K
D
A
D
Y
W
L
R
R
F
E
A
E
P
L
----
P
E
N
T
N
R
Q
L
L
L
Q
F
E
R
---
L
----
V
V
L
D
Y
I
I
-
R
N
T
D
RGN
D
N
W
L
I
K
---
Y
D
C
P
P
-
V
-----
I
K
V
A
---
A
I
D
N
G
L
A
F
P
L
K
H
--
P
D
S
W
R
A
--
Y
P
F
Y
W
A
W
-
L
P
Q
A
K
V
P
F
-
S
----------------
Q
E
I
K
---
D
L
I
L
--
P
K
I
S
D
P
N
F
V
K
D
--
L
E
E
D
--
L
Y
E
L
---
F
K
K
D
P
G
F
D
R
G
Q
F
H
K
Q
-------
I
A
V
M
R
------------
G
Q
I
L
N
L
T
Q
A
L
K
D
N
K
S
P
--
L
H
L
-
V
Q
M
P
P
V
I
V
---
E
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
50.09
15%
2
- C5 -
2XZZ
-
TGM1_HUMAN
A:
[-1-766]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
S
L
T
L
-
L
G
A
A
V
V
G
Q
E
C
E
V
Q
I
V
F
K
N
P
L
------
P
----
V
T
L
-
T
N
V
V
F
R
L
E
G
S
G
L
Q
R
P
K
I
L
N
V
G
D
IG
G
N
E
T
V
T
L
R
Q
---------
S
F
V
P
V
R
P
G
P
R
Q
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
46.45
14%
28
- C3 -
3U4T
-
?
A:
[230-487]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
E
F
R
Y
A
D
F
L
----
F
K
N
N
N
Y
A
E
A
I
E
V
--
F
N
K
L
E
A
K
K
Y
N
S
P
Y
I
Y
N
R
R
--
A
V
C
Y
Y
E
L
A
K
---------
Y
D
L
A
Q
K
D
I
E
T
Y
F
S
K
V
NA
T
K
-------
A
K
S
A
D
F
E
Y
Y
G
K
I
L
M
K
K
G
Q
D
S
L
A
I
-
Q
Q
Y
Q
A
A
V
D
R
D
T
T
R
L
D
-
M
-----
Y
G
Q
I
G
S
Y
F
Y
N
K
G
N
F
P
L
A
I
--
Q
Y
M
E
K
Q
I
R
P
T
T
T
D
P
K
V
-
F
Y
E
L
G
Q
A
Y
Y
Y
N
----
K
E
-
Y
V
K
A
D
S
S
F
V
K
V
L
E
L
K
P
N
-----
I
Y
-----
I
G
Y
L
W
R
A
--
R
A
N
---------
A
A
Q
D
P
DTKQGL
A
K
P
Y
Y
E
K
L
I
E
V
C
A
P
G
G
A
K
--
Y
K
D
E
L
I
-------
E
A
N
E
Y
I
A
Y
Y
Y
T
I
N
R
D
K
V
K
A
D
A
A
W
K
N
I
L
A
L
D
P
T
N
K
K
A
I
D
G
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
44.33
26%
30
- C4 -
3AYI
-
PAO_PSESP
A:
[213-293]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
G
N
P
Q
G
E
N
V
A
M
Y
P
I
A
N
V
D
P
A
K
I
A
A
I
L
------------
N
A
A
T
P
P
A
D
A
L
E
R
I
Q
T
K
--
Y
W
P
-
E
F
I
A
Q
Y
D
G
---
L
T
L
------------------
G
A
A
V
R
E
I
-
V
T
V
------
A
F
E
K
G
T
L
P
P
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
43.32
26%
30
- C4 -
3AYL
-
PAO_PSESP
A:
[213-293]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
G
N
P
Q
G
E
N
V
A
M
Y
P
I
A
N
V
D
P
A
K
I
A
A
I
L
------------
N
A
A
T
P
P
A
D
A
L
E
R
I
Q
T
K
--
Y
W
P
-
E
F
I
A
Q
Y
D
G
---
L
T
L
------------------
G
A
A
V
R
E
I
-
V
T
V
------
A
F
E
K
G
T
L
P
P
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
42.98
26%
31
- C4 -
2YR6
-
PAO_PSESP
A:
[213-293]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
G
N
P
Q
G
E
N
V
A
M
Y
P
I
A
N
V
D
P
A
K
I
A
A
I
L
------------
N
A
A
T
P
P
A
D
A
L
E
R
I
Q
T
K
--
Y
W
P
-
E
F
I
A
Q
Y
D
G
---
L
T
L
------------------
G
A
A
V
R
E
I
-
V
T
V
------
A
F
E
K
G
T
L
P
P
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
42.93
26%
84
- C4 -
1JMA
2
GD_HHV1P
A:
[196-259]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
P
P
S
A
C
L
S
P
Q
A
Y
Q
Q
G
V
T
V
D
S
I
G
M
L
P
R
F
I
P
E
N
Q
R
T
V
A
-
V
----
Y
S
L
K
I
A
G
-
W
H
G
P
---
K
A
P
Y
T
S
---
T
L
L
P
P
E
L
-----
S
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
42.90
26%
31
- C4 -
2YR5
-
PAO_PSESP
A:
[213-293]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
G
N
P
Q
G
E
N
V
A
M
Y
P
I
A
N
V
D
P
A
K
I
A
A
I
L
------------
N
A
A
T
P
P
A
D
A
L
E
R
I
Q
T
K
--
Y
W
P
-
E
F
I
A
Q
Y
D
G
---
L
T
L
------------------
G
A
A
V
R
E
I
-
V
T
V
------
A
F
E
K
G
T
L
P
P
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
42.78
26%
28
- C4 -
2YR4
-
PAO_PSESP
A:
[213-314]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
G
N
P
Q
G
E
N
V
A
M
Y
P
I
A
N
V
D
P
A
K
I
A
A
I
L
------------
N
A
A
T
P
P
A
D
A
L
E
R
I
Q
T
K
--
Y
W
P
-
E
F
I
A
Q
Y
D
G
---
L
T
L
------------------
G
A
A
V
R
E
I
-
V
T
V
------
A
F
E
K
G
T
L
P
P
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
42.65
26%
30
- C4 -
3AYJ
-
PAO_PSESP
A:
[213-293]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
G
N
P
Q
G
E
N
V
A
M
Y
P
I
A
N
V
D
P
A
K
I
A
A
I
L
------------
N
A
A
T
P
P
A
D
A
L
E
R
I
Q
T
K
--
Y
W
P
-
E
F
I
A
Q
Y
D
G
---
L
T
L
------------------
G
A
A
V
R
E
I
-
V
T
V
------
A
F
E
K
G
T
L
P
P
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
38.06
26%
92
* C4 *
1L2G
-
GD_HHV1P
A:
[198-257]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
P
P
S
A
C
L
S
P
Q
A
Y
Q
Q
G
V
T
V
D
S
I
G
M
L
P
R
F
I
P
E
N
Q
R
T
V
A
-
V
----
Y
S
L
K
I
A
G
-
W
H
G
P
---
K
A
P
Y
T
S
---
T
L
L
P
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
36.03
32%
77
- C4 -
3MCX
2
?
A:
[19-72]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
L
D
D
A
Q
I
A
L
N
G
I
--
Y
R
L
-
A
S
G
H
S
Y
Y
G
---
D
N
Y
------------------
W
Y
Y
G
D
C
R
-
A
A
D
V
Q
A
R
I
T
K
G
D
G
K
R
V
S
P
Y
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
35.96
26%
118
- C4 -
3SKU
-
?
A:
[196-252]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
P
P
S
A
C
L
S
P
Q
A
Y
Q
Q
G
V
T
V
D
S
I
G
M
L
P
R
F
I
P
E
N
Q
R
T
V
A
-
V
----
Y
S
L
K
I
A
G
-
W
H
G
P
---
K
A
P
Y
T
S
---
T
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
35.36
11%
-11
- C5 -
1G0D
-
TGM2_PAGMA
A:
[593-667]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
A
------
V
V
W
E
P
L
T
A
Y
V
S
F
T
N
P
L
P
V
P
L
K
G
-
G
-
V
F
T
-
L
E
G
A
G
L
L
-
S
A
---
T
Q
I
H
V
N
----
G
A
-
V
A
P
S
--
G
K
V
S
V
K
L
S
F
S
P
-----
M
R
-----
T
G
V
R
-
K
L
--
L
-
V
---------
D
F
---------
D
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
34.97
26%
113
- C4 -
3U82
-
GD_HHV11
A:
[196-253]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
P
P
S
A
C
L
S
P
Q
A
Y
Q
Q
G
V
T
V
D
S
I
G
M
L
P
R
F
I
P
E
N
Q
R
T
V
A
-
V
----
Y
S
L
K
I
A
G
-
W
H
G
P
---
K
A
P
Y
T
S
---
T
L
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
33.83
15%
97
- C3 -
2KP6
-
?
A:
[1-79]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
T
S
N
H
L
L
P
G
L
F
R
Q
L
G
L
-
E
D
E
P
A
A
I
R
A
F
I
D
S
H
P
L
P
P
R
-
V
----
P
L
P
E
A
P
F
-
W
T
P
A
---
Q
A
A
F
L
R
---
Q
A
L
E
C
D
A
EW---
S
E
A
A
---
D
G
L
A
V
L
L
Q
Q
G
E
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------