@TOME V2.3
(Nov 2016)
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA3324: (2016-02-15 )
MNALLALPDLQPERLFVQSGDVRLAVHCWGAPDNGKPTLLMVHGYPDNHETWLPLIRQLAGRYRIVAYDVRGAGASDKPRWSRDYHLQRLSEDLQAVIRATSPDRPVHLLAHDWGSIQTWESVTDPQCRPLIASYTSISGPCLDHVGFWMREHLRQRSPKALKAVFGQLLHSWYIAFFHTPVVPELLWSAGLARLWPQFLKHAEGVRHPQVNPTQASDGRHGVKLYRGNFIRSLFRPRKRHTEVPVQLIVPTRDRYVGAQLFQHLSLWAPRLWRREASVGHWQLLAEPEQLAGWLGEFIDAQETGESPPALQRAQVRPDASSMNGKLVVVTGAGGGIGRSTLLSFAERGASLLAADLDLEAAERSAELARALGATAHVYQVDVGDTQAMETFAEWVRDTLGVPDVVVSNAGIGMAGPMLDTSPAEWERLLRVNLWSVIDGCRLFGRQMIAANKPGHLVNVASGVAFAPSRNYPAYATSKAAVLMLSECLRAELAGRSIGVTAVCPGFVDTGIVQATRFVGMDAERQARRQAKIQRFYKRRRLSPDTVGEKLVRAVERNKAVVSVGSEVHLGALQWRFAPWATRFLARFDLTS
Atome Classification :
(36 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350..-----.....360-.....-..370.......-380......-.390.......400........410-.......--420.......430.......440.....--..450--.......460...-....470.---......480...--....490.......500.......510.......520.......530.--......540.......550.......560.......570.......580.......590
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MNALLALPDLQP
E
R
L
F
VQSG
D
V
R
L
A
V
H
C
WGAPDNG
K
P
T
L
L
M
V
HGYPDNH
E
T
W
L
P
L
I
R
Q
LAGR
Y
R
I
V
A
Y
D
VRGAGASDKPRWS
R
D
Y
H
L
Q
R
L
S
E
D
L
Q
A
V
I
RATSPDR
P
V
H
L
L
AHDWGSIQ
T
W
ESVTDPQC
R
P
L
I
A
S
YTSISG
P
C
L
D
H
V
G
F
W
M
R
E
H
L
R
QRS
P
K
A
L
K
A
V
F
G
Q
L
L
H
S
W
Y
I
A
F
FHTP
V
V
P
E
L
L
W
S
A
G
L
A
R
L
W
P
Q
F
L
K
H
AEGVRHPQVNPTQASDGRH
G
V
K
LY
R
G
N
F
I
R
S
L
F
RPRKRHTEV
P
V
Q
L
I
VPTRD
R
Y
V
G
A
Q
L
F
Q
H
L
S
L
W
A
P
R
L
W
R
REASVG
H
W
Q
L
LA
E
P
E
Q
L
A
G
W
L
G
E
F
I
D
A
Q
ETGESPPAL
Q
R
AQVRPDASSMNG
K
L
V
V
V
TGAGGGI
G
R
S
T
L
L
S
F
A
E
R
G
A
S
L
L
A-----ADL
D
L
E
A
A
-
E
R
S
A
E
-
L
A
R
A
LGAT
A
H
V
Y
-
Q
V
DVG
D
T
Q
A
-
M
E
T
F
A
E
W
V
R
D
TL-GVP
D
V
V
VSNAGI-GMAGPML--DT
S
P
A
E
W
E
R
L
L
R
V
N
L
W
S
V
I
D
G
C
R
L
F
G
R
Q
--
M
IAAN--KPG
H
L
V
N
VAS
G
V
A-FAPSRNYP---AYAT
S
K
A
A
V
L
M
L
--
S
E
C
L
R
A
E
LAGRSI
G
V
T
A
VCP
G
F
V
D
T
G
I
V
Q
A
T
R
FVGM
D
A
E
R
Q
A
R
R
Q
A
K
I
--
Q
R
F
Y
K
RRRL
S
P
D
T
V
G
E
K
L
V
R
A
V
ERN
K
A
V
V
SVGS
E
V
H
L
G
A
L
Q
W
RF
A
P
W
A
T
R
F
L
A
RFDLTS
130
Fugue
80.69
23%
-56
- C1 -
3LLS
8
?
A:
[50-475]
---------
P
Q
P
E
T
L
R
R
Y
R
A
G
E
P
P
L
T
G
S
L
L
I
G
G
A
G
R
V
V
E
P
L
R
A
A
L
E
K
D
Y
D
L
V
G
N
------
D
S
F
G
G
L
V
F
D
A
T
G
I
--------
T
E
P
A
G
L
K
G
L
H
E
F
F
T
P
V
L
R
N
L
G
R
C
G
R
V
V
V
V
G
G
T
P
E
A
A
A
--------------------------------------------------------------------------------------------------
S
T
N
E
R
I
A
Q
R
A
L
E
G
F
T
R
S
L
G
K
E
L
R
R
G
A
T
T
A
L
V
Y
L
S
P
------------------------
D
A
K
P
A
A
T
G
L
E
S
T
M
R
F
L
L
S
A
K
S
A
Y
V
D
G
Q
V
F
S
V
G
A
D
D
--
S
T
P
P
A
D
W
E
K
P
L
D
G
K
V
A
I
V
T
G
A
A
R
G
I
G
A
T
I
A
E
V
F
A
R
D
G
A
H
V
V
A
-----
I
D
V
-
E
S
A
A
-
E
N
L
A
E
-
T
A
S
K
V
G
G
T
A
L
W
---
L
D
V
T
A
D
D
A
-
V
D
K
I
S
E
H
L
R
D
H
H
G
G
K
A
D
I
L
V
N
N
A
G
I
-
T
R
D
K
L
L
A
--
N
M
D
D
A
R
W
D
A
V
L
A
V
N
L
L
A
P
L
R
L
T
E
G
L
V
G
N
--
G
-
S
I
G
--
E
G
G
R
V
I
G
L
S
S
I
A
G
-
I
A
G
N
R
G
Q
T
---
N
Y
A
T
T
K
A
G
M
I
G
I
--
T
Q
A
L
A
P
G
L
A
A
K
G
I
T
I
N
A
V
A
P
G
F
I
E
R
------
R
L
N
S
L
L
Q
G
G
Q
P
V
D
V
A
E
A
--
I
A
Y
F
A
S
P
A
S
N
A
------------
V
T
G
N
V
I
R
V
C
G
Q
A
M
I
G
A
--------------------
50
PsiBlast_CBE
78.77
34%
-74
- C3 -
2D1Y
1
?
C:
[6-224]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
G
V
L
V
T
G
G
A
R
G
I
G
R
A
I
A
Q
A
F
A
R
E
G
A
L
V
A
L
-----
C
D
L
R
P
E
-----
G
K
E
-
V
A
E
A
I
G
G
A
--
F
F
-
Q
V
D
L
E
D
E
R
E
-
R
V
R
F
V
E
E
A
A
Y
A
L
-
G
R
V
D
V
L
V
N
N
A
A
I
-
A
A
P
G
S
A
L
--
T
V
R
L
P
E
W
R
R
V
L
E
V
N
L
T
A
P
M
H
L
S
A
L
A
A
R
E
--
M
R
K
V
G
--
G
-
G
A
I
V
N
V
A
S
V
Q
G
-
L
F
A
E
Q
E
N
A
---
A
Y
N
A
S
K
G
G
L
V
N
L
--
T
R
S
L
A
L
D
L
A
P
L
R
I
R
V
N
A
V
A
P
G
A
I
A
T
E
A
V
L
E
A
I
A
L
S
P
D
P
E
R
T
R
R
D
W
E
D
L
--
H
A
L
--
R
R
L
G
K
P
E
E
V
A
E
A
V
L
----------------------------------------
51
PsiBlast_CBE
76.67
34%
-74
- C3 -
2D1Y
1
?
B:
[6-224]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
G
V
L
V
T
G
G
A
R
G
I
G
R
A
I
A
Q
A
F
A
R
E
G
A
L
V
A
L
-----
C
D
L
R
P
E
-----
G
K
E
-
V
A
E
A
I
G
G
A
--
F
F
-
Q
V
D
L
E
D
E
R
E
-
R
V
R
F
V
E
E
A
A
Y
A
L
-
G
R
V
D
V
L
V
N
N
A
A
I
-
A
A
P
G
S
A
L
--
T
V
R
L
P
E
W
R
R
V
L
E
V
N
L
T
A
P
M
H
L
S
A
L
A
A
R
E
--
M
R
K
V
G
--
G
-
G
A
I
V
N
V
A
S
V
Q
G
-
L
F
A
E
Q
E
N
A
---
A
Y
N
A
S
K
G
G
L
V
N
L
--
T
R
S
L
A
L
D
L
A
P
L
R
I
R
V
N
A
V
A
P
G
A
I
A
T
E
A
V
L
E
A
I
-------
R
T
R
R
D
W
E
D
L
--
H
A
L
--
R
R
L
G
K
P
E
E
V
A
E
A
V
L
----------------------------------------
49
PsiBlast_CBE
75.74
34%
-72
- C3 -
2D1Y
1
?
D:
[6-224]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
G
V
L
V
T
G
G
A
R
G
I
G
R
A
I
A
Q
A
F
A
R
E
G
A
L
V
A
L
-----
C
D
L
R
P
E
-----
G
K
E
-
V
A
E
A
I
G
G
A
--
F
F
-
Q
V
D
L
E
D
E
R
E
-
R
V
R
F
V
E
E
A
A
Y
A
L
-
G
R
V
D
V
L
V
N
N
A
A
I
-
A
A
P
G
S
A
L
--
T
V
R
L
P
E
W
R
R
V
L
E
V
N
L
T
A
P
M
H
L
S
A
L
A
A
R
E
--
M
R
K
V
G
--
G
-
G
A
I
V
N
V
A
S
V
Q
G
-
L
F
A
E
Q
E
N
A
---
A
Y
N
A
S
K
G
G
L
V
N
L
--
T
R
S
L
A
L
D
L
A
P
L
R
I
R
V
N
A
V
A
P
G
A
I
A
T
E
A
V
L
E
A
I
A
-------
T
R
R
D
W
E
D
L
--
H
A
L
--
R
R
L
G
K
P
E
E
V
A
E
A
V
L
----------------------------------------
13
PsiBlast_PDB
75.63
27%
-65
- C3 -
4URE
1
?
A:
[3-237]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
G
K
T
A
L
V
T
G
A
G
N
G
I
G
R
T
I
A
L
T
Y
A
A
E
G
A
N
V
V
V
-----
S
D
I
S
D
E
W
G
-
R
E
T
L
A
-
L
I
E
G
K
G
G
K
A
V
F
Q
-
H
A
D
T
A
H
P
E
D
-
H
D
E
L
I
A
A
A
K
R
A
F
-
G
R
L
D
I
A
C
N
N
A
G
I
S
G
E
F
T
P
T
A
--
E
T
T
D
A
Q
W
Q
R
V
I
G
I
N
L
S
G
V
F
Y
G
V
R
A
Q
I
R
A
--
M
L
E
T
G
---
G
G
A
I
V
N
I
S
S
I
A
G
-
Q
I
G
I
E
G
I
T
---
P
Y
T
A
A
K
H
G
V
V
G
L
--
T
K
T
V
A
W
E
Y
G
S
K
G
I
R
I
N
S
V
G
P
A
F
I
N
T
T
L
V
Q
-------
N
V
P
L
E
T
R
R
Q
--
L
--
E
Q
M
H
A
L
R
R
L
G
E
T
E
E
V
A
N
L
V
A
W
L
S
S
D
K
A
S
F
V
T
G
S
--------------------------
14
PsiBlast_PDB
75.62
27%
-69
- C3 -
4URF
9
?
A:
[3-237]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
G
K
T
A
L
V
T
G
A
G
N
G
I
G
R
T
I
A
L
T
Y
A
A
E
G
A
N
V
V
V
-----
S
D
I
S
D
E
W
G
-
R
E
T
L
A
-
L
I
E
G
K
G
G
K
A
V
F
Q
-
H
A
D
T
A
H
P
E
D
-
H
D
E
L
I
A
A
A
K
R
A
F
-
G
R
L
D
I
A
C
N
N
A
G
I
S
G
E
F
T
P
T
A
--
E
T
T
D
A
Q
W
Q
R
V
I
G
I
N
L
S
G
V
F
Y
G
V
R
A
Q
I
R
A
--
M
L
E
T
G
---
G
G
A
I
V
N
I
S
S
I
A
G
-
Q
I
G
I
E
G
I
T
---
P
Y
T
A
A
K
H
G
V
V
G
L
--
T
K
T
V
A
W
E
Y
G
S
K
G
I
R
I
N
S
V
G
P
A
F
I
N
T
T
L
V
Q
-------
N
V
P
L
E
T
R
R
Q
--
L
--
E
Q
M
H
A
L
R
R
L
G
E
T
E
E
V
A
N
L
V
A
W
L
S
S
D
K
A
S
F
V
T
G
S
--------------------------
52
PsiBlast_CBE
75.60
34%
-75
- C3 -
2D1Y
1
?
A:
[6-224]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
G
V
L
V
T
G
G
A
R
G
I
G
R
A
I
A
Q
A
F
A
R
E
G
A
L
V
A
L
-----
C
D
L
R
P
E
-----
G
K
E
-
V
A
E
A
I
G
G
A
--
F
F
-
Q
V
D
L
E
D
E
R
E
-
R
V
R
F
V
E
E
A
A
Y
A
L
-
G
R
V
D
V
L
V
N
N
A
A
I
-
A
A
P
G
S
A
L
--
T
V
R
L
P
E
W
R
R
V
L
E
V
N
L
T
A
P
M
H
L
S
A
L
A
A
R
E
--
M
R
K
V
G
--
G
-
G
A
I
V
N
V
A
S
V
Q
G
-
L
F
A
E
Q
E
N
A
---
A
Y
N
A
S
K
G
G
L
V
N
L
--
T
R
S
L
A
L
D
L
A
P
L
R
I
R
V
N
A
V
A
P
G
A
I
A
T
E
A
V
L
E
A
I
A
--------
R
R
D
W
E
D
L
--
H
A
L
--
R
R
L
G
K
P
E
E
V
A
E
A
V
L
----------------------------------------
2
PsiBlast_PDB
74.46
38%
-68
- C3 -
3UF0
1
?
A:
[28-233]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
A
G
R
T
A
V
V
T
G
A
G
S
G
I
G
R
A
I
A
H
G
Y
A
R
A
G
A
H
V
L
A
-----
W
G
R
T
D
G
V
K
-
E
V
A
D
E
-
I
A
D
G
-
G
G
S
A
E
A
V
-
V
A
D
L
A
D
L
E
G
-
A
A
N
V
A
E
E
L
A
A
T
R
-
R
V
-
D
V
L
V
N
N
A
G
I
-
I
A
R
A
P
A
E
--
E
V
S
L
G
R
W
R
E
V
L
T
V
N
L
D
A
A
W
V
L
S
R
S
F
G
T
A
--
M
L
A
-
H
--
G
S
G
R
I
V
T
I
A
S
M
L
S
-
F
Q
G
G
R
N
V
A
---
A
Y
A
A
S
K
H
A
V
V
G
L
--
T
R
A
L
A
S
E
W
A
G
R
G
V
G
V
N
A
L
A
P
G
Y
V
V
T
A
N
T
A
A
L
R
---
A
D
D
E
R
A
A
E
I
T
A
R
I
-------------------------------------------------------------
28
PsiBlast_CBE
74.39
38%
-68
- C3 -
3UF0
1
?
B:
[28-233]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
A
G
R
T
A
V
V
T
G
A
G
S
G
I
G
R
A
I
A
H
G
Y
A
R
A
G
A
H
V
L
A
-----
W
G
R
T
D
G
V
K
-
E
V
A
D
E
-
I
A
D
G
-
G
G
S
A
E
A
V
-
V
A
D
L
A
D
L
E
G
-
A
A
N
V
A
E
E
L
A
A
T
R
-
R
V
-
D
V
L
V
N
N
A
G
I
-
I
A
R
A
P
A
E
--
E
V
S
L
G
R
W
R
E
V
L
T
V
N
L
D
A
A
W
V
L
S
R
S
F
G
T
A
--
M
L
A
-
H
--
G
S
G
R
I
V
T
I
A
S
M
L
S
-
F
Q
G
G
R
N
V
A
---
A
Y
A
A
S
K
H
A
V
V
G
L
--
T
R
A
L
A
S
E
W
A
G
R
G
V
G
V
N
A
L
A
P
G
Y
V
V
T
A
N
T
A
A
L
R
---
A
D
D
E
R
A
A
E
I
T
A
R
I
-------------------------------------------------------------
34
PsiBlast_CBE
74.33
32%
-76
- C3 -
4WEC
4
?
C:
[28-245]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
G
K
V
A
V
I
T
G
G
A
S
G
I
G
L
A
T
G
R
R
L
R
A
E
G
A
T
V
V
V
-----
G
D
I
D
P
T
T
G
-
K
A
A
A
D
-
E
L
E
G
L
-----
F
V
-
P
V
D
V
S
E
Q
E
A
-
V
D
N
L
F
D
T
A
A
S
T
F
-
G
R
V
D
I
A
F
N
N
A
G
I
-
S
P
P
E
D
D
L
IE
N
T
D
L
P
A
W
Q
R
V
Q
D
I
N
L
K
S
V
Y
L
S
C
R
A
A
L
R
H
--
M
V
P
A
G
--
K
-
G
S
I
I
N
T
A
S
F
V
A
V
M
G
S
A
T
S
Q
I
---
S
Y
T
A
S
K
G
G
V
L
A
M
--
S
R
E
L
G
V
Q
Y
A
R
Q
G
I
R
V
N
A
L
C
P
G
P
V
N
T
P
L
L
Q
--
E
L
F
A
K
D
P
E
R
A
A
R
R
L
V
H
I
PL
G
R
F
A
E
P
E
E
L
A
-------------------------------------------------
33
PsiBlast_CBE
74.28
32%
-78
- C3 -
4WEC
4
?
D:
[28-245]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
G
K
V
A
V
I
T
G
G
A
S
G
I
G
L
A
T
G
R
R
L
R
A
E
G
A
T
V
V
V
-----
G
D
I
D
P
T
T
G
-
K
A
A
A
D
-
E
L
E
G
L
-----
F
V
-
P
V
D
V
S
E
Q
E
A
-
V
D
N
L
F
D
T
A
A
S
T
F
-
G
R
V
D
I
A
F
N
N
A
G
I
-
S
P
P
E
D
D
L
IE
N
T
D
L
P
A
W
Q
R
V
Q
D
I
N
L
K
S
V
Y
L
S
C
R
A
A
L
R
H
--
M
V
P
A
G
--
K
-
G
S
I
I
N
T
A
S
F
V
A
V
M
G
S
A
T
S
Q
I
---
S
Y
T
A
S
K
G
G
V
L
A
M
--
S
R
E
L
G
V
Q
Y
A
R
Q
G
I
R
V
N
A
L
C
P
G
P
V
N
T
P
L
L
Q
--
E
L
F
A
K
D
P
E
R
A
A
R
R
L
V
H
I
PL
G
R
F
A
E
P
E
E
L
A
-------------------------------------------------
11
PsiBlast_PDB
74.27
32%
-78
- C3 -
4WEC
4
?
A:
[28-245]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
G
K
V
A
V
I
T
G
G
A
S
G
I
G
L
A
T
G
R
R
L
R
A
E
G
A
T
V
V
V
-----
G
D
I
D
P
T
T
G
-
K
A
A
A
D
-
E
L
E
G
L
-----
F
V
-
P
V
D
V
S
E
Q
E
A
-
V
D
N
L
F
D
T
A
A
S
T
F
-
G
R
V
D
I
A
F
N
N
A
G
I
-
S
P
P
E
D
D
L
IE
N
T
D
L
P
A
W
Q
R
V
Q
D
I
N
L
K
S
V
Y
L
S
C
R
A
A
L
R
H
--
M
V
P
A
G
--
K
-
G
S
I
I
N
T
A
S
F
V
A
V
M
G
S
A
T
S
Q
I
---
S
Y
T
A
S
K
G
G
V
L
A
M
--
S
R
E
L
G
V
Q
Y
A
R
Q
G
I
R
V
N
A
L
C
P
G
P
V
N
T
P
L
L
Q
--
E
L
F
A
K
D
P
E
R
A
A
R
R
L
V
H
I
PL
G
R
F
A
E
P
E
E
L
A
-------------------------------------------------
26
PsiBlast_CBE
74.26
33%
-62
- C3 -
1ZEM
1
?
C:
[3-226]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
F
N
G
K
V
C
L
V
T
G
A
G
G
N
I
G
L
A
T
A
L
R
L
A
E
E
G
T
A
I
A
L
-----
L
D
M
N
R
E
A
L
-
E
K
A
E
A
-
S
V
R
E
K
G
V
E
A
R
S
Y
-
V
C
D
V
T
S
E
E
A
V
I
G
T
V
D
S
V
V
R
D
-
F
-
G
K
I
D
F
L
F
N
N
A
G
Y
Q
G
A
F
A
P
V
Q
--
D
Y
P
S
D
D
F
A
R
V
L
T
I
N
V
T
G
A
F
H
V
L
K
A
V
S
R
Q
--
M
I
T
Q
N
--
Y
-
G
R
I
V
N
T
A
S
M
A
G
-
V
K
G
P
P
N
M
A
---
A
Y
G
T
S
K
G
A
I
I
A
L
--
T
E
T
A
A
L
D
L
A
P
Y
N
I
R
V
N
A
I
S
P
G
Y
M
G
P
G
F
M
W
---------
E
R
Q
V
E
L
Q
A
K
V
--
G
S
Q
Y
--
F
S
T
D
P
K
V
V
A
Q
Q
M
I
G
S
V
-------------------------------------
25
PsiBlast_CBE
74.25
33%
-63
- C3 -
1ZEM
1
?
D:
[3-226]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
F
N
G
K
V
C
L
V
T
G
A
G
G
N
I
G
L
A
T
A
L
R
L
A
E
E
G
T
A
I
A
L
-----
L
D
M
N
R
E
A
L
-
E
K
A
E
A
-
S
V
R
E
K
G
V
E
A
R
S
Y
-
V
C
D
V
T
S
E
E
A
V
I
G
T
V
D
S
V
V
R
D
-
F
-
G
K
I
D
F
L
F
N
N
A
G
Y
Q
G
A
F
A
P
V
Q
--
D
Y
P
S
D
D
F
A
R
V
L
T
I
N
V
T
G
A
F
H
V
L
K
A
V
S
R
Q
--
M
I
T
Q
N
--
Y
-
G
R
I
V
N
T
A
S
M
A
G
-
V
K
G
P
P
N
M
A
---
A
Y
G
T
S
K
G
A
I
I
A
L
--
T
E
T
A
A
L
D
L
A
P
Y
N
I
R
V
N
A
I
S
P
G
Y
M
G
P
G
F
M
W
---------
E
R
Q
V
E
L
Q
A
K
V
--
G
S
Q
Y
--
F
S
T
D
P
K
V
V
A
Q
Q
M
I
G
S
V
-------------------------------------
58
PsiBlast_CBE
74.13
31%
-81
- C3 -
3AK4
1
?
C:
[10-196]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
G
R
K
A
I
V
T
G
G
S
K
G
I
G
A
A
I
A
R
A
L
D
K
A
G
A
T
V
A
I
-----
A
D
L
D
V
M
A
A
-
Q
---
A
-
V
V
A
G
L
E
N
G
G
F
A
V
-
E
V
D
V
T
K
R
A
S
-
V
D
A
A
M
Q
K
A
I
D
A
L
-
G
G
F
D
L
L
C
A
N
A
G
V
-
S
T
M
R
P
A
V
--
D
I
T
D
E
E
W
D
F
N
F
D
V
N
A
R
G
V
F
L
A
N
Q
I
A
C
R
H
--
F
L
A
S
N
--
T
K
G
V
I
V
N
T
A
S
L
A
A
-
K
V
G
A
P
L
L
A
---
H
Y
S
A
S
K
F
A
V
F
G
W
--
T
Q
A
L
A
R
E
M
A
P
K
N
I
R
V
N
C
V
C
P
G
F
V
K
T
A
M
----------------------------------------------------------------------------------
35
PsiBlast_CBE
74.06
32%
-77
- C3 -
4WEC
4
?
B:
[28-245]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
G
K
V
A
V
I
T
G
G
A
S
G
I
G
L
A
T
G
R
R
L
R
A
E
G
A
T
V
V
V
-----
G
D
I
D
P
T
T
G
-
K
A
A
A
D
-
E
L
E
G
L
-----
F
V
-
P
V
D
V
S
E
Q
E
A
-
V
D
N
L
F
D
T
A
A
S
T
F
-
G
R
V
D
I
A
F
N
N
A
G
I
-
S
P
P
E
D
D
L
IE
N
T
D
L
P
A
W
Q
R
V
Q
D
I
N
L
K
S
V
Y
L
S
C
R
A
A
L
R
H
--
M
V
P
A
G
--
K
-
G
S
I
I
N
T
A
S
F
V
A
V
M
G
S
A
T
S
Q
I
---
S
Y
T
A
S
K
G
G
V
L
A
M
--
S
R
E
L
G
V
Q
Y
A
R
Q
G
I
R
V
N
A
L
C
P
G
P
V
N
T
P
L
L
Q
--
E
L
F
A
K
D
P
E
R
A
A
R
R
L
V
H
I
PL
G
R
F
A
E
P
E
E
L
A
-------------------------------------------------
21
PsiBlast_CBE
73.95
33%
-63
- C3 -
1ZEM
1
?
H:
[3-226]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
F
N
G
K
V
C
L
V
T
G
A
G
G
N
I
G
L
A
T
A
L
R
L
A
E
E
G
T
A
I
A
L
-----
L
D
M
N
R
E
A
L
-
E
K
A
E
A
-
S
V
R
E
K
G
V
E
A
R
S
Y
-
V
C
D
V
T
S
E
E
A
V
I
G
T
V
D
S
V
V
R
D
-
F
-
G
K
I
D
F
L
F
N
N
A
G
Y
Q
G
A
F
A
P
V
Q
--
D
Y
P
S
D
D
F
A
R
V
L
T
I
N
V
T
G
A
F
H
V
L
K
A
V
S
R
Q
--
M
I
T
Q
N
--
Y
-
G
R
I
V
N
T
A
S
M
A
G
-
V
K
G
P
P
N
M
A
---
A
Y
G
T
S
K
G
A
I
I
A
L
--
T
E
T
A
A
L
D
L
A
P
Y
N
I
R
V
N
A
I
S
P
G
Y
M
G
P
G
F
M
W
---------
E
R
Q
V
E
L
Q
A
K
V
--
G
S
Q
Y
--
F
S
T
D
P
K
V
V
A
Q
Q
M
I
G
S
V
-------------------------------------
22
PsiBlast_CBE
73.55
33%
-62
- C3 -
1ZEM
1
?
G:
[3-226]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
F
N
G
K
V
C
L
V
T
G
A
G
G
N
I
G
L
A
T
A
L
R
L
A
E
E
G
T
A
I
A
L
-----
L
D
M
N
R
E
A
L
-
E
K
A
E
A
-
S
V
R
E
K
G
V
E
A
R
S
Y
-
V
C
D
V
T
S
E
E
A
V
I
G
T
V
D
S
V
V
R
D
-
F
-
G
K
I
D
F
L
F
N
N
A
G
Y
Q
G
A
F
A
P
V
Q
--
D
Y
P
S
D
D
F
A
R
V
L
T
I
N
V
T
G
A
F
H
V
L
K
A
V
S
R
Q
--
M
I
T
Q
N
--
Y
-
G
R
I
V
N
T
A
S
M
A
G
-
V
K
G
P
P
N
M
A
---
A
Y
G
T
S
K
G
A
I
I
A
L
--
T
E
T
A
A
L
D
L
A
P
Y
N
I
R
V
N
A
I
S
P
G
Y
M
G
P
G
F
M
W
---------
E
R
Q
V
E
L
Q
A
K
V
--
G
S
Q
Y
--
F
S
T
D
P
K
V
V
A
Q
Q
M
I
G
S
V
-------------------------------------
23
PsiBlast_CBE
73.50
33%
-64
- C3 -
1ZEM
1
?
F:
[3-226]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
F
N
G
K
V
C
L
V
T
G
A
G
G
N
I
G
L
A
T
A
L
R
L
A
E
E
G
T
A
I
A
L
-----
L
D
M
N
R
E
A
L
-
E
K
A
E
A
-
S
V
R
E
K
G
V
E
A
R
S
Y
-
V
C
D
V
T
S
E
E
A
V
I
G
T
V
D
S
V
V
R
D
-
F
-
G
K
I
D
F
L
F
N
N
A
G
Y
Q
G
A
F
A
P
V
Q
--
D
Y
P
S
D
D
F
A
R
V
L
T
I
N
V
T
G
A
F
H
V
L
K
A
V
S
R
Q
--
M
I
T
Q
N
--
Y
-
G
R
I
V
N
T
A
S
M
A
G
-
V
K
G
P
P
N
M
A
---
A
Y
G
T
S
K
G
A
I
I
A
L
--
T
E
T
A
A
L
D
L
A
P
Y
N
I
R
V
N
A
I
S
P
G
Y
M
G
P
G
F
M
W
---------
E
R
Q
V
E
L
Q
A
K
V
--
G
S
Q
Y
--
F
S
T
D
P
K
V
V
A
Q
Q
M
I
G
S
V
-------------------------------------
18
PsiBlast_PDB
73.40
29%
-81
- C3 -
2PNF
3
FABG_AQUAE
A:
[5-215]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
G
K
V
S
L
V
T
G
S
T
R
G
I
G
R
A
I
A
E
K
L
A
S
A
G
S
T
V
I
I
-----
T
G
T
S
G
E
R
A
-
K
A
V
A
E
E
I
A
N
K
Y
G
V
K
A
H
G
V
-
E
M
N
L
L
S
E
E
S
-
I
N
K
A
F
E
E
I
Y
N
L
V
-
D
G
I
D
I
L
V
N
N
A
G
I
-
T
R
D
K
L
F
L
--
R
M
S
L
L
D
W
E
E
V
L
K
V
N
L
T
G
T
F
L
V
T
Q
N
S
L
R
K
--
M
I
K
-
Q
--
R
W
G
R
I
V
N
I
S
S
V
V
G
-
F
T
G
N
V
G
Q
V
---
N
Y
S
T
T
K
A
G
L
I
G
F
--
T
K
S
L
A
K
E
L
A
P
R
N
V
L
V
N
A
V
A
P
G
F
I
E
T
D
M
---
T
A
V
L
S
E
E
I
K
Q
K
Y
K
E
Q
I
P
L
--
G
R
F
--------------------------------------------------------
54
PsiBlast_CBE
72.90
31%
-76
- C3 -
3WDS
1
?
C:
[10-196]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
G
R
K
A
I
V
T
G
G
S
K
G
I
G
A
A
I
A
R
A
L
D
K
A
G
A
T
V
A
I
-----
A
D
L
D
V
M
A
A
-
Q
---
A
-
V
V
A
G
L
E
N
G
G
F
A
V
-
E
V
D
V
T
K
R
A
S
-
V
D
A
A
M
Q
K
A
I
D
A
L
-
G
G
F
D
L
L
C
A
N
A
G
V
-
S
T
M
R
P
A
V
--
D
I
T
D
E
E
W
D
F
N
F
D
V
N
A
R
G
V
F
L
A
N
Q
I
A
C
R
H
--
F
L
A
S
N
--
T
K
G
V
I
V
N
T
A
S
L
A
A
-
K
V
G
A
P
L
L
A
---
H
Y
S
A
S
K
F
A
V
F
G
W
--
T
Q
A
L
A
R
E
M
A
P
K
N
I
R
V
N
C
V
C
P
G
F
V
K
T
A
M
----------------------------------------------------------------------------------
59
PsiBlast_CBE
72.89
31%
-78
- C3 -
3AK4
1
?
B:
[10-196]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
G
R
K
A
I
V
T
G
G
S
K
G
I
G
A
A
I
A
R
A
L
D
K
A
G
A
T
V
A
I
-----
A
D
L
D
V
M
A
A
-
Q
---
A
-
V
V
A
G
L
E
N
G
G
F
A
V
-
E
V
D
V
T
K
R
A
S
-
V
D
A
A
M
Q
K
A
I
D
A
L
-
G
G
F
D
L
L
C
A
N
A
G
V
-
S
T
M
R
P
A
V
--
D
I
T
D
E
E
W
D
F
N
F
D
V
N
A
R
G
V
F
L
A
N
Q
I
A
C
R
H
--
F
L
A
S
N
--
T
K
G
V
I
V
N
T
A
S
L
A
A
-
K
V
G
A
P
L
L
A
---
H
Y
S
A
S
K
F
A
V
F
G
W
--
T
Q
A
L
A
R
E
M
A
P
K
N
I
R
V
N
C
V
C
P
G
F
V
K
T
A
M
----------------------------------------------------------------------------------
60
PsiBlast_CBE
72.68
31%
-80
- C3 -
3AK4
1
?
A:
[10-196]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
G
R
K
A
I
V
T
G
G
S
K
G
I
G
A
A
I
A
R
A
L
D
K
A
G
A
T
V
A
I
-----
A
D
L
D
V
M
A
A
-
Q
---
A
-
V
V
A
G
L
E
N
G
G
F
A
V
-
E
V
D
V
T
K
R
A
S
-
V
D
A
A
M
Q
K
A
I
D
A
L
-
G
G
F
D
L
L
C
A
N
A
G
V
-
S
T
M
R
P
A
V
--
D
I
T
D
E
E
W
D
F
N
F
D
V
N
A
R
G
V
F
L
A
N
Q
I
A
C
R
H
--
F
L
A
S
N
--
T
K
G
V
I
V
N
T
A
S
L
A
A
-
K
V
G
A
P
L
L
A
---
H
Y
S
A
S
K
F
A
V
F
G
W
--
T
Q
A
L
A
R
E
M
A
P
K
N
I
R
V
N
C
V
C
P
G
F
V
K
T
A
M
----------------------------------------------------------------------------------
57
PsiBlast_CBE
72.12
31%
-80
- C3 -
3AK4
1
?
D:
[10-196]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
G
R
K
A
I
V
T
G
G
S
K
G
I
G
A
A
I
A
R
A
L
D
K
A
G
A
T
V
A
I
-----
A
D
L
D
V
M
A
A
-
Q
---
A
-
V
V
A
G
L
E
N
G
G
F
A
V
-
E
V
D
V
T
K
R
A
S
-
V
D
A
A
M
Q
K
A
I
D
A
L
-
G
G
F
D
L
L
C
A
N
A
G
V
-
S
T
M
R
P
A
V
--
D
I
T
D
E
E
W
D
F
N
F
D
V
N
A
R
G
V
F
L
A
N
Q
I
A
C
R
H
--
F
L
A
S
N
--
T
K
G
V
I
V
N
T
A
S
L
A
A
-
K
V
G
A
P
L
L
A
---
H
Y
S
A
S
K
F
A
V
F
G
W
--
T
Q
A
L
A
R
E
M
A
P
K
N
I
R
V
N
C
V
C
P
G
F
V
K
T
A
M
----------------------------------------------------------------------------------
56
PsiBlast_CBE
72.11
31%
-78
- C3 -
3WDS
2
?
A:
[10-196]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
G
R
K
A
I
V
T
G
G
S
K
G
I
G
A
A
I
A
R
A
L
D
K
A
G
A
T
V
A
I
-----
A
D
L
D
V
M
A
A
-
Q
---
A
-
V
V
A
G
L
E
N
G
G
F
A
V
-
E
V
D
V
T
K
R
A
S
-
V
D
A
A
M
Q
K
A
I
D
A
L
-
G
G
F
D
L
L
C
A
N
A
G
V
-
S
T
M
R
P
A
V
--
D
I
T
D
E
E
W
D
F
N
F
D
V
N
A
R
G
V
F
L
A
N
Q
I
A
C
R
H
--
F
L
A
S
N
--
T
K
G
V
I
V
N
T
A
S
L
A
A
-
K
V
G
A
P
L
L
A
---
H
Y
S
A
S
K
F
A
V
F
G
W
--
T
Q
A
L
A
R
E
M
A
P
K
N
I
R
V
N
C
V
C
P
G
F
V
K
T
A
M
----------------------------------------------------------------------------------
55
PsiBlast_CBE
71.53
31%
-79
- C3 -
3WDS
1
?
B:
[10-196]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
G
R
K
A
I
V
T
G
G
S
K
G
I
G
A
A
I
A
R
A
L
D
K
A
G
A
T
V
A
I
-----
A
D
L
D
V
M
A
A
-
Q
---
A
-
V
V
A
G
L
E
N
G
G
F
A
V
-
E
V
D
V
T
K
R
A
S
-
V
D
A
A
M
Q
K
A
I
D
A
L
-
G
G
F
D
L
L
C
A
N
A
G
V
-
S
T
M
R
P
A
V
--
D
I
T
D
E
E
W
D
F
N
F
D
V
N
A
R
G
V
F
L
A
N
Q
I
A
C
R
H
--
F
L
A
S
N
--
T
K
G
V
I
V
N
T
A
S
L
A
A
-
K
V
G
A
P
L
L
A
---
H
Y
S
A
S
K
F
A
V
F
G
W
--
T
Q
A
L
A
R
E
M
A
P
K
N
I
R
V
N
C
V
C
P
G
F
V
K
T
A
M
----------------------------------------------------------------------------------
40
PsiBlast_CBE
70.04
34%
-87
- C3 -
3D3W
2
DCXR_HUMAN
B:
[5-190]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
G
R
R
V
L
V
T
G
A
G
K
G
I
G
R
G
T
V
Q
A
L
H
A
T
G
A
R
V
V
A
V
S
RT
Q
A
D
L
D
---------
S
-
L
V
R
E
C
P
G
I
E
P
V
C
--
V
D
L
G
D
W
E
A
-----
T
E
R
A
L
G
S
V
-
G
P
V
D
L
L
V
N
N
A
A
V
-
A
L
L
Q
P
F
L
--
E
V
T
K
E
A
F
D
R
S
F
E
V
N
L
R
A
V
I
Q
V
S
Q
I
V
A
R
G
--
L
I
A
R
G
--
V
P
G
A
I
V
N
V
S
S
Q
C
S
-
Q
R
A
V
T
N
H
S
---
V
Y
C
S
T
K
G
A
L
D
M
L
--
T
K
V
M
A
L
E
L
G
P
H
K
I
R
V
N
A
V
N
P
T
V
V
M
T
S
M
G
Q
A
T
------------------------------------------------------------------------------
42
PsiBlast_CBE
69.53
34%
-90
- C3 -
1WNT
1
DCXR_HUMAN
C:
[5-190]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
G
R
R
V
L
V
T
G
A
G
K
G
I
G
R
G
T
V
Q
A
L
H
A
T
G
A
R
V
V
A
VSRTQ
A
D
L
D
---------
S
-
L
V
R
E
C
P
G
I
E
P
V
C
--
V
D
L
G
D
W
E
A
-----
T
E
R
A
L
G
S
V
-
G
P
V
D
L
L
V
N
N
A
A
V
-
A
L
L
Q
P
F
L
--
E
V
T
K
E
A
F
D
R
S
F
E
V
N
L
R
A
V
I
Q
V
S
Q
I
V
A
R
G
--
L
I
A
R
G
--
V
P
G
A
I
V
N
V
S
S
Q
C
S
-
Q
R
A
V
T
N
H
S
---
V
Y
C
S
T
K
G
A
L
D
M
L
--
T
K
V
M
A
L
E
L
G
P
H
K
I
R
V
N
A
V
N
P
T
V
V
M
T
S
M
G
Q
A
T
------------------------------------------------------------------------------
47
PsiBlast_CBE
69.33
33%
-83
- C3 -
3WYE
1
?
B:
[3-204]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
A
L
V
T
G
A
G
Q
G
I
G
K
A
I
A
L
R
L
V
K
D
G
F
A
V
A
I
-----
A
D
Y
N
D
A
T
A
-
K
A
V
A
S
-
E
I
N
Q
A
G
G
H
A
V
A
V
-
K
V
D
V
S
D
R
D
Q
-
V
F
A
A
V
E
Q
A
R
K
T
L
-
G
G
F
D
V
I
V
N
N
A
G
I
-
A
Q
I
K
P
L
L
--
E
V
T
E
E
D
L
K
Q
I
Y
S
V
N
V
F
S
V
-----
F
F
G
I
Q
A
A
V
E
A
F
K
--
K
E
G
H
G
G
K
I
I
N
A
A
S
-
I
A
A
I
Q
G
F
P
IL
S
A
Y
S
T
T
K
F
A
V
R
G
L
--
T
Q
T
A
A
R
D
L
A
P
L
G
I
T
V
N
G
Y
C
P
G
I
V
G
T
G
M
----------------------------------------------------------------------------------
45
PsiBlast_CBE
69.26
34%
-87
- C3 -
1PR9
3
DCXR_HUMAN
B:
[5-190]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
G
R
R
V
L
V
T
G
A
G
K
G
I
G
R
G
T
V
Q
A
L
H
A
T
G
A
R
V
V
A
VSRTQ
A
D
L
D
---------
S
-
L
V
R
E
C
P
G
I
E
P
V
C
--
V
D
L
G
D
W
E
A
-----
T
E
R
A
L
G
S
V
-
G
P
V
D
L
L
V
N
N
A
A
V
-
A
L
L
Q
P
F
L
--
E
V
T
K
E
A
F
D
R
S
F
E
V
N
L
R
A
V
I
Q
V
S
Q
I
V
A
R
G
--
L
I
A
R
G
--
V
P
G
A
I
V
N
V
S
S
Q
C
S
-
Q
R
A
V
T
N
H
S
---
V
Y
C
S
T
K
G
A
L
D
M
L
--
T
K
V
M
A
L
E
L
G
P
H
K
I
R
V
N
A
V
N
P
T
V
V
M
T
S
M
G
Q
A
T
------------------------------------------------------------------------------
44
PsiBlast_CBE
69.17
34%
-87
- C3 -
1WNT
1
DCXR_HUMAN
A:
[5-190]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
G
R
R
V
L
V
T
G
A
G
K
G
I
G
R
G
T
V
Q
A
L
H
A
T
G
A
R
V
V
A
V
S
R
T
Q
A
D
L
D
---------
S
-
L
V
R
E
C
P
G
I
E
P
V
C
--
V
D
L
G
D
W
E
A
-----
T
E
R
A
L
G
S
V
-
G
P
V
D
L
L
V
N
N
A
A
V
-
A
L
L
Q
P
F
L
--
E
V
T
K
E
A
F
D
R
S
F
E
V
N
L
R
A
V
I
Q
V
S
Q
I
V
A
R
G
--
L
I
A
R
G
--
V
P
G
A
I
V
N
V
S
S
Q
C
S
-
Q
R
A
V
T
N
H
S
---
V
Y
C
S
T
K
G
A
L
D
M
L
--
T
K
V
M
A
L
E
L
G
P
H
K
I
R
V
N
A
V
N
P
T
V
V
M
T
S
M
G
Q
A
T
------------------------------------------------------------------------------
10
PsiBlast_PDB
69.06
31%
-79
- C3 -
2GDZ
1
PGDH_HUMAN
A:
[2-197]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
M
V
N
G
K
V
A
L
V
T
G
A
A
Q
G
I
G
R
A
F
A
E
A
L
L
L
K
G
A
K
V
A
L
-----
V
D
W
N
L
E
A
G
V
Q
C
K
A
A
-
L
H
E
Q
F
E
P
Q
K
T
L
F
I
Q
C
D
V
A
D
Q
Q
Q
-
L
R
D
T
F
R
K
V
V
D
H
F
-
G
R
L
D
I
L
V
N
N
A
G
V
-----------
N
N
E
K
N
W
E
K
T
L
Q
I
N
L
V
S
V
I
S
G
T
Y
L
G
L
D
Y
--
M
S
K
Q
N
GG
E
G
G
I
I
I
N
M
S
S
L
A
G
-
L
M
P
V
A
Q
Q
P
---
V
Y
C
A
S
K
H
G
I
V
G
F
T
R
S
A
A
L
A
A
N
L
M
N
S
G
V
R
L
N
A
I
C
P
G
F
V
N
T
A
I
L
E
S
I
E
-----------------------------------------------------------------------------
43
PsiBlast_CBE
69.01
34%
-85
- C3 -
1WNT
1
DCXR_HUMAN
B:
[5-190]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
G
R
R
V
L
V
T
G
A
G
K
G
I
G
R
G
T
V
Q
A
L
H
A
T
G
A
R
V
V
A
VSRTQ
A
D
L
D
---------
S
-
L
V
R
E
C
P
G
I
E
P
V
C
--
V
D
L
G
D
W
E
A
-----
T
E
R
A
L
G
S
V
-
G
P
V
D
L
L
V
N
N
A
A
V
-
A
L
L
Q
P
F
L
--
E
V
T
K
E
A
F
D
R
S
F
E
V
N
L
R
A
V
I
Q
V
S
Q
I
V
A
R
G
--
L
I
A
R
G
--
V
P
G
A
I
V
N
V
S
S
Q
C
S
-
Q
R
A
V
T
N
H
S
---
V
Y
C
S
T
K
G
A
L
D
M
L
--
T
K
V
M
A
L
E
L
G
P
H
K
I
R
V
N
A
V
N
P
T
V
V
M
T
S
M
G
Q
A
T
------------------------------------------------------------------------------
46
PsiBlast_CBE
68.92
34%
-87
- C3 -
1PR9
3
DCXR_HUMAN
A:
[5-190]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
G
R
R
V
L
V
T
G
A
G
K
G
I
G
R
G
T
V
Q
A
L
H
A
T
G
A
R
V
V
A
V
S
RT
Q
A
D
L
D
---------
S
-
L
V
R
E
C
P
G
I
E
P
V
C
--
V
D
L
G
D
W
E
A
-----
T
E
R
A
L
G
S
V
-
G
P
V
D
L
L
V
N
N
A
A
V
-
A
L
L
Q
P
F
L
--
E
V
T
K
E
A
F
D
R
S
F
E
V
N
L
R
A
V
I
Q
V
S
Q
I
V
A
R
G
--
L
I
A
R
G
--
V
P
G
A
I
V
N
V
S
S
Q
C
S
-
Q
R
A
V
T
N
H
S
---
V
Y
C
S
T
K
G
A
L
D
M
L
--
T
K
V
M
A
L
E
L
G
P
H
K
I
R
V
N
A
V
N
P
T
V
V
M
T
S
M
G
Q
A
T
------------------------------------------------------------------------------
41
PsiBlast_CBE
68.35
34%
-84
- C3 -
1WNT
1
DCXR_HUMAN
D:
[5-190]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
G
R
R
V
L
V
T
G
A
G
K
G
I
G
R
G
T
V
Q
A
L
H
A
T
G
A
R
V
V
A
VSRTQ
A
D
L
D
---------
S
-
L
V
R
E
C
P
G
I
E
P
V
C
--
V
D
L
G
D
W
E
A
-----
T
E
R
A
L
G
S
V
-
G
P
V
D
L
L
V
N
N
A
A
V
-
A
L
L
Q
P
F
L
--
E
V
T
K
E
A
F
D
R
S
F
E
V
N
L
R
A
V
I
Q
V
S
Q
I
V
A
R
G
--
L
I
A
R
G
--
V
P
G
A
I
V
N
V
S
S
Q
C
S
-
Q
R
A
V
T
N
H
S
---
V
Y
C
S
T
K
G
A
L
D
M
L
--
T
K
V
M
A
L
E
L
G
P
H
K
I
R
V
N
A
V
N
P
T
V
V
M
T
S
M
G
Q
A
T
------------------------------------------------------------------------------
48
PsiBlast_CBE
66.98
33%
-80
- C3 -
3WYE
1
?
A:
[3-189]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
A
L
V
T
G
A
G
Q
G
I
G
K
A
I
A
L
R
L
V
K
D
G
F
A
V
A
I
-----
A
D
Y
N
D
A
T
A
-
K
A
V
A
S
-
E
I
N
Q
A
G
G
H
A
V
A
V
-
K
V
D
V
S
D
R
D
Q
-
V
F
A
A
V
E
Q
A
R
K
T
L
-
G
G
F
D
V
I
V
N
N
A
G
I
-
A
Q
I
K
P
L
L
--
E
V
T
E
E
D
L
K
Q
I
Y
S
V
N
V
F
S
V
-----
F
F
G
I
Q
A
A
V
E
A
F
K
--
K
E
G
H
G
G
K
I
I
N
A
A
S
-
I
A
A
I
Q
G
F
P
IL
S
A
Y
S
T
T
K
F
A
V
R
G
L
--
T
Q
T
A
A
R
D
L
A
P
L
G
I
T
V
N
G
Y
C
P
G
I
V
G
T
G
M
----------------------------------------------------------------------------------