@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA4037: (2016-02-23 )
MIDIDRLSKRFSGRTVVNDLSFRIDRGEIVGLLGPNGAGKSTTLKMLSGFLAPSAGSVRIFGFDMQDKARQAQKLIGYLPENAPSYGEMTVEGFLAFVASIRDYSGREKRRRIDSAMDCMELRDERRSIIETLSKGFKRRVALAQAILHDPELLLLDEPTDGLDPNQKHQVRQLVKNLSESKIVVISTHILEEVSFMCSRALVINGGRLLADNTPGELRTRSRYHHAVSLSIEAPVDPLAIAMLPGVAGIEGRPDRAGTLTILARPGAQILPALNRLIHGSGWRVSGVRTEHGQLEEVFRQLTREPPA
Atome Classification :
(23 SA)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10.-.--......20........30........40........50........60.-----.....-..---70...--.....80....-..--..90........100-.....--..110-------........120...--..--..130--------.......140.......150.......160.......170.-.....-.180.--.--.----....-..190.......200.......210.......220.......230---.........240.......250.......260.......270---------.......280.......290.......300......------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MI
D
I
D
R
L
S
K
R
FS-G--
R
T
V
VND
L
S
F
R
IDR
G
E
I
V
G
L
LGPNGAGK
S
T
T
L
K
M
L
S
G
F
LAPSAG
S
V
R
I
F
G
-----FD
M
Q
D
-
K
A
---
R
Q
A
Q
K
--
L
I
G
YLPENAPS-Y
G
--
E
M
T
V
E
G
F
L
A
F
V
A
S
I
R-DYS
G
R
--
E
K
R
R
--------
R
I
D
S
A
M
D
C
M
E
L
R
D
E
--
R
R
--
S
I
I
E
T
--------
L
S
K
G
F
K
R
R
V
A
L
A
Q
A
I
LHDP
E
L
L
L
L
DEPTDGLDPN
Q
K
H
Q
V
R
Q
-
L
V
K
NL-SE--S--
K
--
I
----
V
V
I
S
-
T
H
I
L
E
E
V
S
F
M
CS
R
A
L
V
ING
G
R
L
LADNTPGE
L
R
TRS
R
Y
H
H
A
V
S
L
-----
S
IEAPVD
P
L
A
I
A
MLPGVAGIEGRPDRA
G
T
L
T
I
L
ARPG
A
Q
I
L
P
---------
A
L
N
R
L
IHGSG
W
R
V
SGVRTEHG
Q
L
E
E
V
F
R
Q
L
TREPPA------------------
54
Fugue
89.39
25%
-86
- C1 -
1Z47
1
?
A:
[11-355]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GSM
T
I
E
F
V
G
V
E
K
I
Y
P
-
G
G-
A
R
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
------
K
R
V
T
-
D
L
---
P
P
Q
K
R
--
N
V
G
L
V
F
Q
N
Y
A
L
-
F
Q
--
H
M
T
V
Y
D
N
V
S
F
G
L
R
E
K
-
R
V
P
K
D
--
E
M
D
A
--------
R
V
R
E
L
L
R
F
M
R
L
E
S
Y
--
A
N
--
R
F
P
H
E
--------
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
-
F
V
R
Q
V
-
H
D
--
E
M
G
V
--
T
----
S
V
F
V
-
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
V
Y
E
K
P
G
T
L
F
V
A
S
F
IGE
S
N
V
W
T
R
A
V
Q
N
G
R
I
E
V
A
G
A
A
L
P
V
D
P
A
V
S
E
G
S
E
V
A
V
V
V
R
P
K
D
V
E
L
Q
P
A
S
EREAHA
Q
V
V
R
S
A
F
K
G
S
Y
S
A
C
W
I
R
T
K
D
G
E
V
W
E
V
H
V
P
S
A
D
R
H
R
W
SPG
A
W
V
H
M
N
V
T
R
W
F
I
F
P
R
50
HHSearch
85.58
36%
-108
- C1 -
1VPL
2
?
A:
[16-235]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
V
V
K
D
L
R
K
R
I
G
-
K
--
K
E
I
L
K
G
I
S
F
E
I
E
E
G
E
I
F
G
L
I
G
P
N
G
A
G
K
T
T
T
L
R
I
I
S
T
L
I
K
P
S
S
G
I
V
T
V
F
G
-----
K
N
V
V
E
-
E
P
---
H
E
V
R
K
--
L
I
S
Y
L
P
E
E
A
G
A
-
Y
R
--
N
M
Q
G
I
E
Y
L
R
F
V
A
G
F
Y
-
A
S
S
S
S
--
E
I
E
E
--------
M
V
E
R
A
T
E
I
A
G
L
G
E
K
--
I
K
--
D
R
V
S
T
--------
Y
S
K
G
M
V
R
K
L
L
I
A
R
A
L
M
V
N
P
R
L
A
I
L
D
E
P
T
S
G
L
D
V
L
N
A
R
E
V
R
K
-
I
L
K
Q
A
-
S
Q
E
-
G
--
L
--
T
----
I
L
V
S
-
S
H
N
M
L
E
V
E
F
L
C
D
R
I
A
L
I
H
N
G
T
I
V
E
T
G
T
V
E
E
L
K
E
------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
84.09
35%
-104
- C1 -
1VPL
2
?
A:
[18-241]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
K
D
L
R
K
R
I
G
-
K
--
K
E
I
L
K
G
I
S
F
E
I
E
E
G
E
I
F
G
L
I
G
P
N
G
A
G
K
T
T
T
L
R
I
I
S
T
L
I
K
P
S
S
G
I
V
T
V
F
G
-----
K
N
V
V
E
-
E
P
---
H
E
V
R
K
--
L
I
S
Y
L
P
E
E
A
G
A
-
Y
R
--
N
M
Q
G
I
E
Y
L
R
F
V
A
G
F
Y
-
A
S
S
S
S
--
E
I
E
E
--------
M
V
E
R
A
T
E
I
A
G
L
G
E
K
--
I
K
--
D
R
V
S
T
--------
Y
S
K
G
M
V
R
K
L
L
I
A
R
A
L
M
V
N
P
R
L
A
I
L
D
E
P
T
S
G
L
D
V
L
N
A
R
E
V
R
K
-
I
L
K
Q
A
-
S
Q
--
E
--
G
--
L
T
---
I
L
V
S
-
S
H
N
M
L
E
V
E
F
L
C
D
R
I
A
L
I
H
N
G
T
I
V
E
T
G
T
V
E
E
L
K
E
R
Y
K
A
Q
N
------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
81.22
36%
-101
- C1 -
4P32
2
LPTB_ECOLI
B:
[8-223]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
K
A
Y
K
-
G
--
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
DDISL
L
P
L
H
A
-
R
A
---
R
R
G
-----
I
G
Y
L
P
Q
E
A
S
I
-
F
R
--
R
L
S
V
Y
D
N
L
M
A
V
L
Q
I
R
D
D
L
S
A
E
--
Q
R
E
D
--------
R
A
N
E
L
M
E
E
F
H
I
E
H
L
--
R
D
--
S
M
G
Q
S
--------
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
-
I
I
E
H
L
-
R
D
--
S
--
G
--
L
G---
V
L
I
T
-
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
I
--------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
79.03
36%
-102
- C1 -
4P33
7
LPTB_ECOLI
A:
[8-223]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
K
A
Y
K
-
G
--
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
DDISL
L
P
L
H
A
-
R
A
---
R
R
G
-----
I
G
Y
L
P
Q
E
A
S
I
-
F
R
--
R
L
S
V
Y
D
N
L
M
A
V
L
Q
I
R
D
D
L
S
A
E
--
Q
R
E
D
--------
R
A
N
E
L
M
E
E
F
H
I
E
H
L
--
R
D
--
S
M
G
Q
S
--------
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
Q
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
-
I
I
E
H
L
-
R
D
--
S
--
G
--
L
G
---
V
L
I
T
-
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
I
--------------------------------------------------------------------------------------------------------------------------
32
HHSearch
78.53
31%
-95
- C1 -
1Z47
1
?
A:
[15-236]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
F
V
G
V
E
K
I
Y
P
G
G
--
A
R
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
-----
K
R
V
T
D
-
L
P
----
P
Q
K
R
--
N
V
G
L
V
F
Q
N
Y
A
L
-
F
Q
--
H
M
T
V
Y
D
N
V
S
F
G
L
R
E
K
-
R
V
P
K
D
--
E
M
D
A
--------
R
V
R
E
L
L
R
F
M
R
L
E
S
Y
--
A
N
--
R
F
P
H
E
--------
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
-
F
V
R
Q
V
-
H
D
E
M
G
--
V
--
T
----
S
V
F
V
-
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
V
Y
E
K
-----------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
78.36
36%
-98
- C1 -
4P32
2
LPTB_ECOLI
A:
[8-223]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
K
A
Y
K
-
G
--
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
DDISL
L
P
L
H
A
-
R
A
---
R
R
G
-----
I
G
Y
L
P
Q
E
A
S
I
-
F
R
--
R
L
S
V
Y
D
N
L
M
A
V
L
Q
I
R
D
D
L
S
A
E
--
Q
R
E
D
--------
R
A
N
E
L
M
E
E
F
H
I
E
H
L
--
R
D
--
S
M
G
Q
S
--------
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
-
I
I
E
H
L
-
R
D
--
S
--
G
--
L
G---
V
L
I
T
-
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
I
--------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
78.24
36%
-100
- C1 -
4P33
6
LPTB_ECOLI
B:
[8-223]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
K
A
Y
K
-
G
--
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
DDISL
L
P
L
H
A
-
R
A
---
R
R
G
-----
I
G
Y
L
P
Q
E
A
S
I
-
F
R
--
R
L
S
V
Y
D
N
L
M
A
V
L
Q
I
R
D
D
L
S
A
E
--
Q
R
E
D
--------
R
A
N
E
L
M
E
E
F
H
I
E
H
L
--
R
D
--
S
M
G
Q
S
--------
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
Q
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
-
I
I
E
H
L
-
R
D
--
S
--
G
--
L
G---
V
L
I
T
-
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
I
--------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
78.18
36%
-96
- C1 -
4QC2
2
?
A:
[9-224]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
K
A
Y
K
-
G
--
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
DDISL
L
P
L
H
A
-
R
A
---
R
R
G
-----
I
G
Y
L
P
Q
E
A
S
I
-
F
R
--
R
L
S
V
Y
D
N
L
M
A
V
L
Q
I
R
D
D
L
S
A
E
--
Q
R
E
D
--------
R
A
N
E
L
M
E
E
F
H
I
E
H
L
--
R
D
--
S
M
G
Q
S
--------
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
-
I
I
E
H
L
-
R
D
--
S
--
G
--
L
G
---
V
L
I
T
-
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
I
--------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
76.81
32%
-104
- C1 -
4WBS
1
?
B:
[42-265]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
N
L
K
K
R
Y
G
-
S
--
R
T
V
V
K
D
V
S
L
D
V
K
S
G
E
V
V
G
L
L
G
P
N
G
A
G
K
T
T
S
F
Y
M
I
V
G
L
V
P
L
D
A
G
E
I
D
L
D
G
KS---
I
S
L
L
P
-
I
H
---
K
R
A
S
L
--
G
L
S
Y
L
P
Q
E
A
S
V
-
F
R
--
K
L
S
V
E
E
N
I
R
A
V
L
E
L
Q
---
V
G
----
G
K
R
LS
K
D
A
I
A
S
R
T
E
A
L
L
D
E
L
Q
I
S
H
L
--
R
E
--
N
P
A
L
S
--------
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
T
N
P
S
F
I
L
L
D
E
P
F
A
G
V
D
P
I
A
V
L
E
I
Q
K
-
I
V
K
F
L
-
K
Q
--
R
--
N
--
I
G
---
V
L
I
T
-
D
H
N
V
R
E
T
L
G
I
C
D
H
A
Y
I
I
S
D
G
S
V
L
A
A
G
A
P
G
D
I
--------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
76.14
36%
-94
- C1 -
4QC2
2
?
B:
[9-224]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
K
A
Y
K
-
G
--
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
DDISL
L
P
L
H
A
-
R
A
---
R
R
G
-----
I
G
Y
L
P
Q
E
A
S
I
-
F
R
--
R
L
S
V
Y
D
N
L
M
A
V
L
Q
I
R
D
D
L
S
A
E
--
Q
R
E
D
--------
R
A
N
E
L
M
E
E
F
H
I
E
H
L
--
R
D
--
S
M
G
Q
S
--------
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
-
I
I
E
H
L
-
R
D
--
S
--
G
--
L
G---
V
L
I
T
-
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
I
--------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
76.03
34%
-100
- C1 -
4RVC
-
?
A:
[3-222]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
E
V
K
D
L
S
G
G
Y
T
-
A
--
Q
N
V
L
E
D
V
T
F
V
V
D
R
G
E
M
V
A
L
I
G
L
N
G
A
G
K
S
T
T
I
K
H
I
I
G
L
M
E
P
R
R
G
A
I
S
I
N
G
-----
Y
R
L
A
D
-
G
P
---
E
T
Y
R
R
--
Q
F
A
Y
I
P
E
T
P
V
L
-
Y
E
--
E
L
T
L
E
E
H
L
R
L
A
A
M
A
Y
-
G
L
S
E
A
--
E
Y
E
R
--------
R
L
P
P
L
L
R
--
E
F
R
L
E
--
R
R
LS
S
F
P
A
H
--------
F
S
K
G
M
K
Q
K
V
M
I
V
C
A
F
L
L
E
P
P
L
Y
I
I
D
E
P
F
L
G
L
D
P
L
A
I
H
---
A
-
L
L
E
R
M
-
N
E
--
Q
--
K
--
A
K
G
A
G
I
L
L
S
-
T
H
I
L
A
T
A
E
R
Y
C
D
S
F
V
I
L
H
N
G
R
V
K
A
K
G
T
L
D
D
I
R
-------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
75.07
32%
-107
- C1 -
4WBS
1
?
A:
[42-265]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
N
L
K
K
R
Y
G
-
S
--
R
T
V
V
K
D
V
S
L
D
V
K
S
G
E
V
V
G
L
L
G
P
N
G
A
G
K
T
T
S
F
Y
M
I
V
G
L
V
P
L
D
A
G
E
I
D
L
D
G
KS---
I
S
L
L
P
-
I
H
---
K
R
A
S
L
--
G
L
S
Y
L
P
Q
E
A
S
V
-
F
R
--
K
L
S
V
E
E
N
I
R
A
V
L
E
L
Q
---
V
G
D
--
D
G
K
R
LS
K
D
A
I
A
S
R
T
E
A
L
L
D
E
L
Q
I
S
H
L
--
R
E
--
N
P
A
L
S
--------
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
T
N
P
S
F
I
L
L
D
E
P
F
A
G
V
D
P
I
A
V
L
E
I
Q
K
-
I
V
K
F
L
-
K
Q
--
R
--
N
--
I
G
---
V
L
I
T
-
D
H
N
V
R
E
T
L
G
I
C
D
H
A
Y
I
I
S
D
G
S
V
L
A
A
G
A
P
G
D
I
--------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
72.13
31%
-87
- C1 -
2IT1
1
?
B:
[4-227]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
L
E
N
I
V
K
K
F
G
-
N
--
F
T
A
L
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
Y
--------
F
D
E
K
D
-
V
T
---
E
L
P
P
K
DR
N
V
G
L
V
F
Q
N
W
A
L
-
Y
P
--
H
M
T
V
Y
K
N
I
A
F
P
L
E
L
R
-
K
A
P
R
E
--
E
I
D
K
--------
K
V
R
E
V
A
K
M
L
H
I
D
K
L
--
L
N
--
R
Y
P
W
Q
--------
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
-
E
L
K
R
L
-
Q
K
--
E
--
L
GI
T
----
T
V
Y
V
-
T
H
D
Q
A
E
A
L
A
M
A
D
R
I
A
V
I
R
E
G
E
I
L
Q
V
G
T
P
D
E
V
Y
Y
K
P
K
Y
--------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
71.68
33%
-97
- C1 -
4MKI
4
ECFA2_CALS4
B:
[27-249]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
D
I
N
F
S
I
D
D
E
E
F
V
G
I
I
G
H
T
G
S
G
K
S
T
L
I
Q
Q
L
N
G
L
L
K
P
S
K
G
K
I
Y
I
N
G
-----
I
D
I
T
D
-
K
K
VS
L
K
D
I
R
K
--
Q
V
G
-
L
V
F
Q
Y
P
E
-
Y
Q
LF
E
E
T
V
F
K
D
I
A
F
G
P
S
N
L
-
G
L
S
E
E
--
E
V
K
E
--------
R
V
Y
E
A
M
E
I
V
G
I
S
K
E
LA
D
K
--
S
P
F
E
---------
L
S
G
G
Q
K
R
R
V
A
I
A
G
I
L
A
M
R
P
K
I
L
I
L
D
E
P
T
A
G
L
D
P
K
G
K
Q
E
I
L
N
-
K
I
K
E
I
-
H
D
--
K
--
Y
K
M
I
----
T
I
L
V
-
S
H
N
M
E
D
I
A
R
I
A
D
K
I
I
V
M
N
R
G
K
I
E
L
I
G
T
P
R
E
V
F
R
E
A
E
R
L
E
K
I
G
L
-----
S
V
-------------------------------------------------------------------------------------------------------
39
HHSearch
71.64
33%
-86
- C1 -
2YYZ
3
?
A:
[3-223]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
I
R
V
V
N
L
K
K
Y
F
G
-
K
--
V
K
A
V
D
G
V
S
F
E
V
K
D
G
E
F
V
A
L
L
G
P
S
G
C
G
K
T
T
T
L
L
M
L
A
G
I
Y
K
P
T
S
G
E
I
Y
F
D
D
-----
V
L
V
N
D
-
I
P
----
P
K
Y
R
--
E
V
G
M
V
F
Q
N
Y
A
L
-
Y
P
--
H
M
T
V
F
E
N
I
A
F
P
L
R
A
R
-
R
I
S
K
D
--
E
V
E
K
--------
R
V
V
E
I
A
R
K
L
L
I
D
N
L
--
L
D
--
R
K
P
T
Q
--------
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
Q
P
K
V
L
L
F
D
E
P
L
S
N
L
D
A
N
L
R
M
I
M
R
A
-
E
I
K
H
L
-
Q
Q
E
L
G
--
I
--
T
----
S
V
Y
V
-
T
H
D
Q
A
E
A
M
T
M
A
S
R
I
A
V
F
N
Q
G
K
L
V
Q
Y
G
T
P
D
E
V
Y
D
------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
71.63
33%
-96
- C1 -
4MKI
4
ECFA2_CALS4
A:
[27-249]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
D
I
N
F
S
I
D
D
E
E
F
V
G
I
I
G
H
T
G
S
G
K
S
T
L
I
Q
Q
L
N
G
L
L
K
P
S
K
G
K
I
Y
I
N
G
-----
I
D
I
T
D
-
K
K
VS
L
K
D
I
R
K
--
Q
V
G
-
L
V
F
Q
Y
P
E
-
Y
Q
LF
E
E
T
V
F
K
D
I
A
F
G
P
S
N
L
-
G
L
S
E
E
--
E
V
K
E
--------
R
V
Y
E
A
M
E
I
V
G
I
S
K
E
LA
D
K
--
S
P
F
E
---------
L
S
G
G
Q
K
R
R
V
A
I
A
G
I
L
A
M
R
P
K
I
L
I
L
D
E
P
T
A
G
L
D
P
K
G
K
Q
E
I
L
N
-
K
I
K
E
I
-
H
D
--
K
--
Y
K
M
I
----
T
I
L
V
-
S
H
N
M
E
D
I
A
R
I
A
D
K
I
I
V
M
N
R
G
K
I
E
L
I
G
T
P
R
E
V
F
R
E
A
E
R
L
E
K
I
G
L
-----
S
V
-------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
71.31
31%
-83
- C1 -
2IT1
-
?
A:
[4-227]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
L
E
N
I
V
K
K
F
G
-
N
--
F
T
A
L
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
Y
--------
F
D
E
K
D
-
V
T
---
E
L
P
P
K
DR
N
V
G
L
V
F
Q
N
W
A
L
-
Y
P
--
H
M
T
V
Y
K
N
I
A
F
P
L
E
L
R
-
K
A
P
R
E
--
E
I
D
K
--------
K
V
R
E
V
A
K
M
L
H
I
D
K
L
--
L
N
--
R
Y
P
W
Q
--------
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
-
E
L
K
R
L
-
Q
K
--
E
--
L
GI
T
----
T
V
Y
V
-
T
H
D
Q
A
E
A
L
A
M
A
D
R
I
A
V
I
R
E
G
E
I
L
Q
V
G
T
P
D
E
V
Y
Y
K
P
K
Y
--------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
70.67
32%
-99
- C1 -
3FVQ
3
FBPC_NEIG1
B:
[5-226]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
H
I
G
H
L
S
K
S
F
Q
-
N
--
T
P
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
KTI--
F
S
K
N
T
-
N
L
---
P
V
R
E
R
--
R
L
G
Y
L
V
Q
E
G
V
L
-
F
P
--
H
L
T
V
Y
R
N
I
A
Y
--
G
L
G
-
N
G
K
G
R
TA
Q
E
R
Q
--------
R
I
E
A
M
L
E
L
T
G
I
S
E
L
--
A
G
--
R
Y
P
H
E
--------
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
--
G
--
K
--
S
----
A
V
F
V
-
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
G
R
I
L
Q
T
A
S
P
H
E
L
--------------------------------------------------------------------------------------------------------------------------
59
Fugue
70.38
21%
-80
- C1 -
3B60
2
MSBA_SALTY
A:
[10-581]
W
Q
T
F
R
R
L
W
P
T
I
A
PFK
A
G
L
I
V
A
G
I
A
L
I
L
N
A
A
S
D
T
F
M
L
S
L
LKPLLDDGFGKTDRSVLLW
M
P
L
V
V
I
G
L
M
I
L
R
G
I
T
S
Y
I
S
S
Y
C
I
S
W
V
S
G
K
V
V
M
T
M
R
R
R
L
F
G
H
M
M
G
MPVAFFDKQS
T
G
T
L
L
S
R
I
T
Y
D
S
E
Q
V
A
S
S
S
S
G
A
L
I
T
V
V
R
E
G
A
S
I
I
G
L
F
I
M
M
FYYS
W
Q
L
S
I
I
L
V
V
L
A
P
I
V
S
I
A
I
R
V
V
S
K
R
F
R
S
I
S
K
N
M
Q
N
T
M
G
Q
V
T
T
S
A
E
Q
M
L
K
G
H
KEVLIFGG
Q
E
V
E
T
K
R
F
D
K
V
S
N
K
M
R
L
Q
G
M
K
M
V
S
A
S
S
I
S
D
P
I
I
Q
L
I
A
S
L
A
L
A
F
V
L
Y
A
A
S
FPSVMDSLT
A
G
T
I
T
V
V
F
S
S
M
I
A
L
M
R
P
L
K
S
L
T
N
V
N
A
Q
F
Q
R
G
M
A
A
C
Q
T
L
F
A
I
L
D
SEQEK
D
E
G
K
RVIDRATG
D
L
E
F
R
N
V
T
F
T
Y
P
-
G
RE
V
P
A
L
R
N
I
N
L
K
I
P
A
G
K
T
V
A
L
V
G
R
S
G
S
G
K
S
T
I
A
S
L
I
T
R
F
Y
D
I
D
E
G
H
I
L
M
D
G
-----
H
D
L
R
E
Y
T
L
---
A
S
L
R
N
--
Q
V
A
L
V
S
Q
N
V
H
L
-
F
N
--
D
-
T
V
A
N
N
I
A
Y
--
A
R
T
-
E
E
Y
S
R
--
E
Q
I
E
--------
E
A
A
R
M
A
Y
A
M
D
F
I
N
K
--
M
D
--
N
G
L
D
T
I
I
G
ENGVL
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
L
R
D
S
P
I
L
I
L
D
E
A
T
S
A
L
D
T
E
S
E
R
A
I
Q
A
-
A
L
D
E
L
-
Q
K
--
N
--
R
--
T
----
S
L
V
I
-
A
H
R
L
S
T
I
E
Q
-
A
D
E
I
V
V
V
E
D
G
I
I
V
E
R
G
T
H
S
E
L
L
A
Q
H
G
V
----------------------------------------------------------------------------------------
Y
A
Q
L
H
K
M
Q
F
G
------------------
13
PsiBlast_PDB
64.68
32%
-94
- C1 -
1VCI
1
?
A:
[13-239]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
K
L
E
N
L
T
K
R
F
G
-
N
--
F
T
A
V
N
K
L
N
L
T
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
P
T
E
G
R
I
Y
-
F
G
-----
D
R
D
V
T
-
Y
L
---
P
P
K
D
R
--
N
I
S
M
V
F
Q
---------
H
M
T
V
Y
E
N
I
A
F
P
L
--
K
-
K
F
P
K
D
--
E
I
D
K
--------
R
V
R
W
A
A
E
L
L
Q
I
E
E
L
--
L
N
--
R
Y
P
A
Q
--------
L
S
G
G
Q
R
Q
R
V
A
V
A
R
A
I
V
V
E
P
D
V
L
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
A
M
R
A
-
E
I
K
K
L
-
Q
Q
--
K
L
-
K
--
V
----
T
T
I
Y
V
T
H
D
Q
V
E
A
M
T
M
G
D
R
I
A
V
M
N
R
G
Q
L
L
Q
I
G
S
P
T
E
V
Y
L
R
-----------------------------------------------------------------------------------------------------------------------
31
PsiBlast_CBE
57.59
32%
-92
- C1 -
4HLU
3
ECFA1_THEMA
C:
[12-206]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
L
N
S
V
S
F
R
Y
N
-
G
--
D
Y
V
L
K
D
V
N
A
E
F
E
T
G
K
I
Y
V
V
V
G
K
N
G
S
G
K
T
T
L
L
K
I
L
A
G
L
L
A
-
A
A
G
E
I
F
L
D
G
-------
S
P
A
-
D
P
---
F
L
L
R
K
--
N
V
G
Y
V
F
Q
N
P
S
S
Q
I
I
--
G
A
T
V
E
E
D
V
A
F
S
L
E
I
M
-
G
L
D
E
S
--
E
M
R
K
--------
R
I
K
K
V
L
E
L
V
G
L
S
G
L
--
A
A
--
A
D
P
L
N
--------
L
S
G
G
Q
K
Q
R
L
A
I
A
S
M
L
A
R
D
T
R
F
L
A
L
D
E
P
V
S
M
L
D
P
P
S
Q
R
E
I
F
Q
-
V
L
E
S
L
K
N
E
--
G
--
K
--
G
----
I
I
L
V
-
T
H
E
L
E
Y
L
D
D
M
-----------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
53.86
35%
-19
- C1 -
4P31
2
LPTB_ECOLI
A:
[8-223]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
K
A
Y
K
-
G
--
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
DDISL
L
P
L
H
A
-
R
A
---
R
R
G
-----
I
G
Y
L
P
Q
E
A
S
I
-
F
R
--
R
L
S
V
Y
D
N
L
M
A
V
L
Q
I
R
D
D
L
S
A
E
--
Q
R
E
D
--------
R
A
N
E
L
M
E
E
F
H
I
E
H
L
--
R
D
--
S
M
G
Q
S
--------
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
-
I
I
E
H
L
-
R
D
--
S
--
G
--
L
G
---
V
L
I
T
-
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
I
--------------------------------------------------------------------------------------------------------------------------