@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA4910: (2016-03-02 )
MSDKILSVEHLMMHFGGIKALNDVNLDVERGSITALIGPNGAGKTTVFNCLTGFYKATGGNILLNTQGRTTDVIQVLGEPFQLDDFVKPPQLGSRLYYKMFGGTHLVNRAGLARTFQNIRLFKDMSVVENLLVAQHMFVNRNLLAGILNTPGYRRAESEALDHAFYWLEVVDLVDCANRLAGEMSYGQQRRLEIARAMCTRPELICLDEPAAGLNPAETHALSNIVRYLRDHHGITVLLIEHDMGMVMNISDHIIVLDHGDVIARGNPEQIRHDEKVIAAYLGADEEELS
Atome Classification :
(20 SA)
.........10....-..----..20-........30........40........50........60........70........80........90........100.......110.......120.......130.......140....--...150...---....160-......--------.170-....-....180.......190.......200........210.......220.......230.......240.......250.......-260.......270--..---..--.--..--..280.......290------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MSD
K
I
L
S
V
E
H
L
M
M
H
F-GG----I
K
A
L
-
N
D
V
N
L
D
V
ERG
S
I
T
A
L
IGPNGAG
K
T
T
V
F
N
C
L
T
G
F
Y
KATGG
N
I
L
L
NTQGR
T
T
D
V
I
Q
V
LGEPFQLDDFVKPPQLG
S
R
L
Y
Y
K
MFGG
T
H
L
V
N
R
A
G
L
A
R
T
F
Q
N
I
R
L
F
K
D
M
S
V
V
E
N
L
L
V
A
Q
H
M
F
V
N
R
N
L
L
A
G
--
I
LNTPGYRR---
A
E
S
E
A
L
D
-
H
A
F
Y
W
L
--------
E
V
V
--
D
L
V
D
-
C
A
N
R
L
A
GEMSY
G
Q
Q
R
R
L
E
I
A
R
A
MCT-RP
E
L
I
C
LDEPAAGLN
P
A
E
T
H
A
L
S
N
I
V
R
Y
L
R
DHH
G
I
T
V
L
L
I
EHDM
G
M
V
M
NISD
H
I
I
V
L
DH-G
D
V
I
ARG
N
P
E
Q
----
I
R
---
H
D
--
E
--
K
V
--
I
A
A
Y
LGAD
E
E
ELS--------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
91.42
34%
-138
- C1 -
1G6H
3
LIVG_METJA
A:
[6-256]
---
E
I
L
R
T
E
N
I
V
K
Y
F
-
G
E
----
F
K
A
L
-
D
G
V
S
I
S
V
N
K
G
D
V
T
L
I
I
G
P
N
G
S
G
K
S
T
L
I
N
V
I
T
G
F
L
K
A
D
E
G
R
V
Y
F
E
N
K
D
I
T
N
K
------
E
P
A
E
L
Y
H
Y
------------------------
G
I
V
R
T
F
Q
T
P
Q
P
L
K
E
M
T
V
L
E
N
L
L
I
G
E
-------
I
C
P
G
ES
P
L
N
S
L
F
Y
K
K
WIP
K
E
E
E
M
V
E
-
K
A
F
K
I
L
--------
E
F
L
--
K
L
S
H
-
L
Y
D
R
K
A
G
E
L
S
G
G
Q
M
K
L
V
E
I
G
R
A
L
M
T
-
N
P
K
M
I
V
M
D
E
P
I
A
G
V
A
P
G
L
A
H
D
I
F
N
H
V
L
E
L
K
-
A
K
G
I
T
F
L
I
I
E
H
R
L
D
I
V
L
N
Y
I
D
H
L
Y
V
M
F
N
-
G
Q
I
I
A
E
G
R
G
E
E
E
I
K
N
V
L
---
S
D
--
P
--
K
V
--
V
E
I
Y
I
G
---------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
89.42
34%
-129
- C1 -
1GAJ
7
LIVG_METJA
A:
[6-256]
---
E
I
L
R
T
E
N
I
V
K
Y
F
-
G
E
----
F
K
A
L
-
D
G
V
S
I
S
V
N
K
G
D
V
T
L
I
I
G
P
N
G
S
G
K
S
T
L
I
N
V
I
T
G
F
L
K
A
D
E
G
R
V
Y
F
E
N
K
D
I
T
N
K
------
E
P
A
E
L
Y
H
Y
------------------------
G
I
V
R
T
F
Q
T
P
Q
P
L
K
E
M
T
V
L
E
N
L
L
I
G
E
-----
I
N
P
G
E
S
--
P
L
N
S
L
F
Y
K
K
WIP
K
E
E
E
M
V
E
-
K
A
F
K
I
L
--------
E
F
L
--
K
L
S
H
-
L
Y
D
R
K
A
G
E
L
S
G
G
Q
M
K
L
V
E
I
G
R
A
L
M
T
-
N
P
K
M
I
V
M
D
Q
P
I
A
G
V
A
P
G
L
A
H
D
I
F
N
H
V
L
E
L
K
-
A
K
G
I
T
F
L
I
I
E
H
R
L
D
I
V
L
N
Y
I
D
H
L
Y
V
M
F
N
-
G
Q
I
I
A
E
G
R
G
E
E
E
I
K
N
V
L
---
S
D
--
P
--
K
V
--
V
E
I
Y
I
G
---------------------------------------------------------------------------------------------------------------
65
Fugue
89.10
27%
-129
- C1 -
3TUZ
3
METN_ECOLI
H:
[23-362]
---
H
M
I
K
L
S
N
I
T
K
V
F
-
H
Q
GTRT
I
Q
A
L
-
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
-----------------------------------
L
S
E
S
E
L
T
K
A
R
R
Q
I
G
M
I
F
Q
H
F
---
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
E
--
L
D
N
T
P
K
--------
D
E
V
K
R
-
R
V
T
E
L
L
--------
S
L
V
--
G
L
G
D
-
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
-
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
-
G
E
L
I
E
Q
D
T
V
S
E
----
V
F
SHP
K
T
--
P
--
L
A
--
Q
K
F
I
Q
S
T
L
H
L
D
I
P
EDYQERLQAEPFTDCVPMLRLEFTGQSVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHHVKVEV---------------
61
Fugue
88.05
25%
-120
- C1 -
1OXS
23
?
C:
[1-352]
M
V
R
--
I
I
V
K
N
V
S
K
V
F
-
K
K
GK--
V
V
A
L
-
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
R
L
V
A
S
N
G
K
L
I
V
P
----------------------------
P
E
D
R
K
I
G
M
V
F
Q
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
A
F
P
L
T
N
-----------------
M
K
M
---
S
K
E
E
I
R
K
-
R
V
E
E
V
A
--------
K
I
L
--
D
I
H
H
-
V
L
N
H
F
P
R
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
-
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
K
-
G
K
L
V
Q
V
G
K
P
E
D
----
L
Y
---
D
N
PV
S
--
I
Q
--
V
A
S
L
I
G
-
E
I
N
E
L
E
GKVTNEGVVIGSLRFPVSVSSDRAIIGIRPEDVKLSKDVIKDDSWILVGKGKVKVIGYQGGLFRITITPLDSEEEIFTYSDHPIHSGEEVLVYVRKDKIKVFEK
54
HHSearch
88.02
37%
-126
- C1 -
1G6H
3
LIVG_METJA
A:
[4-243]
-
T
M
E
I
L
R
T
E
N
I
V
K
Y
F
-
G
E
----
F
K
A
L
-
D
G
V
S
I
S
V
N
K
G
D
V
T
L
I
I
G
P
N
G
S
G
K
S
T
L
I
N
V
I
T
G
F
L
K
A
D
E
G
R
V
Y
F
E
N
K
D
I
T
--------------
N
K
---
E
P
------------
A
E
-
L
Y
H
Y
G
I
V
R
T
F
Q
T
P
Q
P
L
K
E
M
T
V
L
E
N
L
L
I
G
E
I
C
P
G
E
S
P
L
N
S
L
--
F
Y
K
K
W
I
--
P
---
K
E
E
E
M
V
E
-
K
A
F
K
I
L
--------
E
F
L
--
K
L
S
H
-
L
Y
D
R
K
A
G
E
L
S
G
G
Q
M
K
L
V
E
I
G
R
A
L
M
T
-
N
P
K
M
I
V
M
D
E
P
I
A
G
V
A
P
G
L
A
H
D
I
F
N
H
V
L
E
L
K
A
-
K
G
I
T
F
L
I
I
E
H
R
L
D
I
V
L
N
Y
I
D
H
L
Y
V
M
F
N
-
G
Q
I
I
A
E
G
R
G
E
E
----
E
I
---
K
N
------------------------------------------------------------------------------------------------------------------------------
63
Fugue
87.14
26%
-129
- C1 -
1Z47
1
?
A:
[11-355]
-
G
S
M
T
I
E
F
V
G
V
E
K
I
Y
P
G
G
----
A
R
S
V
-
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
--
G
K
R
V
T
D
L
P
-------------------------------
P
Q
K
R
N
V
G
L
V
F
Q
N
Y
A
L
F
Q
H
M
T
V
Y
D
N
V
S
F
G
L
R
E
-----------------
K
R
V
---
P
K
D
E
M
D
A
-
R
V
R
E
L
L
--------
R
F
M
--
R
L
E
S
-
Y
A
N
R
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
-
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
E
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
-
G
N
V
E
Q
F
G
T
P
E
E
----
V
Y
---
E
K
PG
T
--
L
F
--
V
A
S
F
I
G
E
S
N
V
W
T
R
A
V
Q
NG
R
I
E
V
AG
A
A
L
P
V
DPAVSEG
S
E
V
A
V
V
V
R
PKD
V
E
L
Q
P
A
S
EREAHAQVV
R
S
A
F
KGS
Y
S
A
C
W
I
R
T
KD
G
E
V
W
E
V
H
V
P
SADRHRWSPG
A
W
V
H
M
N
V
T
R
W
F
I
F
P
R---
2
PsiBlast_PDB
86.83
34%
-125
- C1 -
1G9X
4
LIVG_METJA
A:
[6-256]
---
E
I
L
R
T
E
N
I
V
K
Y
F
-
G
E
----
F
K
A
L
-
D
G
V
S
I
S
V
C
K
G
D
V
T
L
I
I
G
P
N
G
S
G
K
S
T
L
I
N
V
I
T
G
F
L
K
A
D
E
G
R
V
Y
F
E
N
K
D
I
T
N
K
------
E
P
A
E
L
Y
H
Y
------------------------
G
I
V
R
T
F
Q
T
P
Q
P
L
K
E
M
T
V
L
E
N
L
L
I
G
E
-----
I
N
P
G
E
S
--
P
L
N
S
L
F
Y
K
K
WIP
K
E
E
E
M
V
E
-
K
A
F
K
I
L
--------
E
F
L
--
K
L
S
H
-
L
Y
D
R
K
A
G
E
L
S
G
G
Q
M
K
L
V
E
I
G
R
A
L
M
T
-
N
P
K
M
I
V
M
D
E
P
I
A
G
V
A
P
G
L
A
H
D
I
F
N
H
V
L
E
L
K
-
A
K
G
I
T
F
L
I
I
E
H
R
L
D
I
V
L
N
Y
I
D
H
L
Y
V
M
F
N
-
G
Q
I
I
A
E
G
R
G
E
E
E
I
K
N
V
L
---
S
D
--
P
--
K
V
--
V
E
I
Y
I
G
---------------------------------------------------------------------------------------------------------------
56
Fugue
86.36
36%
-131
- C1 -
1G6H
3
LIVG_METJA
A:
[4-257]
-
T
M
E
I
L
R
T
E
N
I
V
K
Y
F
-
G
-E---
F
K
A
L
D-
G
V
S
I
S
V
N
K
G
D
V
T
L
I
I
G
P
N
G
S
G
K
S
T
L
I
N
V
I
T
G
F
L
K
A
D
E
G
R
V
Y
F
E
N
----
K
D
I
T
N
K
-------------------------
E
P
A
E
L
Y
H
Y
G
-
I
V
R
T
F
Q
T
P
Q
P
L
K
E
M
T
V
L
E
N
L
L
I
G
E
I
C
P
G
E
S
P
L
N
S
L
--
F
Y
K
K
W
I
P
K
E
---
E
E
M
V
E
K
A
-
F
K
I
L
E
F
L
KLSHLYD-------------
R
K
A
G
E
L
S
G
G
Q
M
K
L
V
E
I
G
R
A
L
M
T
N-
P
K
M
I
V
M
D
E
P
I
A
G
V
A
P
G
L
A
H
D
I
F
N
H
V
L
E
L
K
A
K
-
G
I
T
F
L
I
I
E
H
R
L
D
I
V
L
N
Y
I
D
H
L
Y
V
M
F
-N
G
Q
I
I
A
E
G
R
G
E
E
E
I
K
N
V
L
---
S
D
--
P
--
K
V
--
V
E
I
Y
I
G
E
--------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
86.23
34%
-121
- C1 -
1G9X
3
LIVG_METJA
C:
[6-256]
---
E
I
L
R
T
E
N
I
V
K
Y
F
-
G
E
----
F
K
A
L
-
D
G
V
S
I
S
V
C
K
G
D
V
T
L
I
I
G
P
N
G
S
G
K
S
T
L
I
N
V
I
T
G
F
L
K
A
D
E
G
R
V
Y
F
E
N
K
D
I
T
N
K
------
E
P
A
E
L
Y
H
Y
------------------------
G
I
V
R
T
F
Q
T
P
Q
P
L
K
E
M
T
V
L
E
N
L
L
I
G
E
-----
I
N
P
G
E
S
--
P
L
N
S
L
F
Y
K
K
WIP
K
E
E
E
M
V
E
-
K
A
F
K
I
L
--------
E
F
L
--
K
L
S
H
-
L
Y
D
R
K
A
G
E
L
S
G
G
Q
M
K
L
V
E
I
G
R
A
L
M
T
-
N
P
K
M
I
V
M
D
E
P
I
A
G
V
A
P
G
L
A
H
D
I
F
N
H
V
L
E
L
K
-
A
K
G
I
T
F
L
I
I
E
H
R
L
D
I
V
L
N
Y
I
D
H
L
Y
V
M
F
N
-
G
Q
I
I
A
E
G
R
G
E
E
EIKN
V
L
---
S
D
--
P
--
K
V
--
V
E
I
Y
I
G
---------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
85.43
34%
-133
- C1 -
1G9X
3
LIVG_METJA
B:
[6-256]
---
E
I
L
R
T
E
N
I
V
K
Y
F
-
G
E
----
F
K
A
L
-
D
G
V
S
I
S
V
C
K
G
D
V
T
L
I
I
G
P
N
G
S
G
K
S
T
L
I
N
V
I
T
G
F
L
K
A
D
E
G
R
V
Y
F
E
N
K
D
I
T
N
K
------
E
P
A
E
L
Y
H
Y
------------------------
G
I
V
R
T
F
Q
T
P
Q
P
L
K
E
M
T
V
L
E
N
L
L
I
G
E
-----
I
N
P
G
E
S
--
P
L
N
S
L
F
Y
K
K
WIP
K
E
E
E
M
V
E
-
K
A
F
K
I
L
--------
E
F
L
--
K
L
S
H
-
L
Y
D
R
K
A
G
E
L
S
G
G
Q
M
K
L
V
E
I
G
R
A
L
M
T
-
N
P
K
M
I
V
M
D
E
P
I
A
G
V
A
P
G
L
A
H
D
I
F
N
H
V
L
E
L
K
-
A
K
G
I
T
F
L
I
I
E
H
R
L
D
I
V
L
N
Y
I
D
H
L
Y
V
M
F
N
-
G
Q
I
I
A
E
G
R
G
E
E
EIKN
V
L
---
S
D
--
P
--
K
V
--
V
E
I
Y
I
G
---------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
84.17
28%
-137
- C1 -
1JI0
1
?
A:
[2-238]
V
S
D
I
V
L
E
V
Q
S
L
H
V
Y
Y
-
G
A
----
I
H
A
I
-
K
G
I
D
L
K
V
P
R
G
Q
I
V
T
L
I
G
A
N
G
A
G
K
T
T
T
L
S
A
I
A
G
L
V
R
A
Q
K
G
K
I
I
F
N
G
Q
-----------------
D
I
T
N
K
P
-------------
A
H
V
I
N
R
M
G
I
A
L
V
P
E
G
R
R
I
F
P
E
L
T
V
Y
E
N
L
M
M
G
-------------------
A
Y
N
R
---
K
D
K
E
G
I
K
-
R
D
L
E
W
I
--------
F
S
L
F
P
R
L
K
E
-
R
L
K
Q
L
G
G
T
L
S
G
G
E
Q
Q
M
L
A
I
G
R
A
L
M
S
-
R
P
K
L
L
M
M
D
E
P
S
L
G
L
A
P
I
L
V
S
E
V
F
E
V
I
Q
K
I
-
N
Q
E
G
T
T
I
L
L
V
E
Q
N
A
L
G
A
L
K
V
A
H
Y
G
Y
V
L
E
T
-
G
Q
I
V
L
E
G
K
A
S
E
----
L
L
---
D
N
--
E
--
M
V
--
R
K
A
Y
L
G
---------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
83.23
28%
-136
- C1 -
4WBS
1
?
A:
[40-277]
-----
L
V
V
R
N
L
K
K
R
Y
-
G
S
----
R
T
V
V
-
K
D
V
S
L
D
V
K
S
G
E
V
V
G
L
L
G
P
N
G
A
G
K
T
T
S
F
Y
M
I
V
G
L
V
P
L
D
A
G
E
I
D
L
D
--
G
K
S
I
S
L
L
P
I
----------------------------
H
K
R
A
S
L
G
L
S
Y
L
P
Q
E
A
S
V
F
R
K
L
S
V
E
E
N
I
R
A
V
L
E
L
Q
V
G
D
D
-----------
G
K
R
L
---
S
K
D
A
I
A
S
-
R
T
E
A
L
L
--------
D
E
L
--
Q
I
S
H
-
L
R
E
N
P
A
L
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
T
-
N
P
S
F
I
L
L
D
E
P
F
A
G
V
D
P
I
A
V
L
E
I
Q
K
I
V
K
F
L
K
Q
R
N
-
I
G
V
L
I
T
D
H
N
V
R
E
T
L
G
I
C
D
H
A
Y
I
I
S
D
-
G
S
V
L
A
A
G
A
P
G
D
----
I
I
---
E
N
--
E
--
S
V
--
R
R
V
Y
L
G
---------------------------------------------------------------------------------------------------------------
46
HHSearch
81.25
31%
-133
- C1 -
1JI0
1
?
A:
[3-237]
-
S
D
I
V
L
E
V
Q
S
L
H
V
Y
Y
-
G
A
----
I
H
A
I
-
K
G
I
D
L
K
V
P
R
G
Q
I
V
T
L
I
G
A
N
G
A
G
K
T
T
T
L
S
A
I
A
G
L
V
R
A
Q
K
G
K
I
I
F
N
G
Q
D
I
--------------
T
N
K
---
P
A
------------
H
V
-
I
N
R
M
G
I
A
L
V
P
E
G
R
R
I
F
P
E
L
T
V
Y
E
N
L
M
M
G
A
Y
N
R
K
D
K
E
---------------------
G
I
K
R
-
D
L
E
W
I
F
--------
S
L
F
P
-
R
L
K
E
-
R
L
K
Q
L
G
G
T
L
S
G
G
E
Q
Q
M
L
A
I
G
R
A
L
M
S
-
R
P
K
L
L
M
M
D
E
P
S
L
G
L
A
P
I
L
V
S
E
V
F
E
V
I
Q
K
I
N
Q
-
E
G
T
T
I
L
L
V
E
Q
N
A
L
G
A
L
K
V
A
H
Y
G
Y
V
L
E
T
-
G
Q
I
V
L
E
G
K
A
S
E
----
L
L
---
D
N
--
E
--
M
V
--
R
K
A
Y
L
----------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
80.84
27%
-132
- C1 -
4P33
7
LPTB_ECOLI
A:
[3-235]
-----
L
T
A
K
N
L
A
K
A
Y
-
K
G
----
R
R
V
V
-
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
D
D
I
S
L
L
P
L
------------------------------
H
A
R
A
R
R
G
I
G
Y
L
P
Q
E
A
S
I
F
R
R
L
S
V
Y
D
N
L
M
A
V
L
Q
I
---
R
D
D
L
S
A
----------------
E
Q
R
E
D
-
R
A
N
E
L
M
--------
E
E
F
--
H
I
E
H
-
L
R
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
-
N
P
K
F
I
L
L
D
Q
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
D
-
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
-
G
H
L
I
A
H
G
T
P
T
E
----
I
L
---
Q
D
--
E
--
H
V
--
K
R
V
Y
L
G
---------------------------------------------------------------------------------------------------------------
42
HHSearch
80.70
26%
-123
* C1 *
3TUI
1
METN_ECOLI
C:
[23-255]
---
H
M
I
K
L
S
N
I
T
K
V
F
-
H
Q
GTRT
I
Q
A
L
-
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
--------------
T
L
---
S
E
-----------
S
E
L
T
K
A
R
R
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
E
L
D
N
T
P
--------------------
K
D
E
V
K
R
-
R
V
T
E
L
L
--------
S
L
V
--
G
L
G
D
-
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
-
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
-
G
E
L
I
E
Q
D
T
V
S
E
----
V
F
---
S
H
--
P
---------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
80.26
27%
-130
- C1 -
4P32
2
LPTB_ECOLI
A:
[3-234]
-----
L
T
A
K
N
L
A
K
A
Y
-
K
G
----
R
R
V
V
-
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
D
D
I
S
L
L
P
L
------------------------------
H
A
R
A
R
R
G
I
G
Y
L
P
Q
E
A
S
I
F
R
R
L
S
V
Y
D
N
L
M
A
V
L
Q
I
---
R
D
D
L
S
A
----------------
E
Q
R
E
D
-
R
A
N
E
L
M
--------
E
E
F
--
H
I
E
H
-
L
R
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
-
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
D
-
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
-
G
H
L
I
A
H
G
T
P
T
E
----
I
L
---
Q
D
--
E
--
H
V
--
K
R
V
Y
L
----------------------------------------------------------------------------------------------------------------
45
HHSearch
80.02
27%
-127
- C1 -
2OLJ
4
?
A:
[22-261]
--
L
Q
M
I
D
V
H
Q
L
K
K
S
F
-
G
S
----
L
E
V
L
-
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
------------
K
D
T
---
N
L
------------
N
--
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
-------------------
P
R
E
K
A
E
A
-
K
A
M
E
L
L
--------
D
K
V
--
G
L
K
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
----
L
F
---
D
R
--
P
--
Q
H
E
R
T
K
A
F
L
S
K
--------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
80.02
27%
-121
- C1 -
4QC2
2
?
A:
[4-236]
-----
L
T
A
K
N
L
A
K
A
Y
-
K
G
----
R
R
V
V
-
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
D
D
I
S
----------------
L
L
P
--------------
L
H
A
R
A
R
R
G
I
G
Y
L
P
Q
E
A
S
I
F
R
R
L
S
V
Y
D
N
L
M
A
V
L
Q
I
---
R
D
D
L
S
A
----------------
E
Q
R
E
D
-
R
A
N
E
L
M
--------
E
E
F
--
H
I
E
H
-
L
R
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
-
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
D
-
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
-
G
H
L
I
A
H
G
T
P
T
E
----
I
L
---
Q
D
--
E
--
H
V
--
K
R
V
Y
L
G
---------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
79.79
26%
-120
- C1 -
1Z47
1
?
A:
[13-247]
M
T
I
E
F
V
G
V
E
K
I
--
Y
P
-
G
G
----
A
R
S
V
-
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
-
R
V
T
D
L
---------------
P
P
Q
-----------------
K
R
N
V
G
L
V
F
Q
N
Y
A
L
F
------------
Q
H
M
T
V
Y
D
N
V
S
F
G
--
L
R
E
----
K
R
---
V
P
K
D
E
M
D
A
R
V
R
E
L
L
--------
R
F
M
--
R
L
E
S
-
Y
A
N
R
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
-
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
E
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
-
G
N
V
E
Q
F
G
T
P
E
E
----
V
Y
---
E
K
--
P
--
G
T
L
F
V
A
S
F
I
G
---------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
79.79
25%
-131
- C1 -
2IT1
-
?
A:
[4-235]
-----
I
K
L
E
N
I
V
K
K
F
-
G
N
----
F
T
A
L
-
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
Y
F
D
E
K
----
D
V
T
E
L
------------
P
P
K
-----------------
D
R
N
V
G
L
V
F
Q
N
W
A
L
Y
P
H
M
T
V
Y
K
N
I
A
F
P
L
E
L
------------------
R
K
---
A
P
R
E
E
I
D
-
K
K
V
R
E
V
--------
A
K
M
--
L
H
I
D
K
L
L
N
R
Y
P
W
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
-
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
K
R
L
Q
K
E
L
G
I
T
T
V
Y
V
T
H
D
Q
A
E
A
L
A
M
A
D
R
I
A
V
I
R
E
-
G
E
I
L
Q
V
G
T
P
D
E
----
V
Y
---
Y
K
--
P
KY
K
F
--
V
G
G
F
L
G
---------------------------------------------------------------------------------------------------------------