@TOME V3
(Feb 2022)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : D3QBL2_STANL: (2019-01-27 )
MCGMTSLVDTALRLTYPDYRWRRLEAARPILGVRTYALTGRYRLVVKIALEEDLIDEDHGPCGEARRLAWLAGHGIPVPEVVDTGVMGDDEYLVLRLPDDAVPADQVASEQRLAACDAVADVARAVHGIDHRGCPFDRRLRVTIPRAKEACLFAEIRSRDPMAKLTSLIAKALWVGREEPVVCHGDLRPDSVLIDARTRRVAAVLDVARLGVADRYTDLAAATRGWRAGGLDKRVWWRYGEIPADADRVRLYRLLAEFCLPRPGTGRVEPRQDGGDVRRCGFVRQLGHGVPGDPTVFHQRRGLVVLETFTRQVRGGGVDTGQEIGFGGFEHLALPAHRHRHVDGTRRPLARGQAGFLGQFAPGGLRGRLTGFDAAAGRLPQQVGVDGVTPAQHQDPVVGVQAQHAGTLTIDFGHDAQVMARRRGGALAWAPGCPCHRVRCGSC
Atome Classification :
(22 SA)
.........10........-------20....--....30.......----.-40.--..---.....---.50.....--...60........70....-.....80...---...-..90.----...-.-...100.---..------------....----110----.....---....120.......130...-.--..------.----140......------.150-----....-...--.160------.----..----..---....170.---..-------..--------.----.180.......190.......200.......210.------......220..----------...---.------.--230........240-..---......250.......260.......270.......280.......290.......300.......310.......320........330.......340.......350.......360.......370.-......380.......390.......400.......410.......420.......430.......440.
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MCG
M
T
S
L
V
D
T
A
L
RLTYPDY-------
R
W
R
R
L
E--AARP
I
L
G
V
R
T
Y
A
L
----T-G-
R
--
Y
R
---
L
V
V
K
I
---ALEE
D
L
ID--EDHGP
C
G
E
A
R
R
L
A
W
-
L
AGH-GIPV
P
E
V
VDT---GVM-GDD
E
Y
----
L
V
L
-R-LPDDAV
P
---
A
D
------------
Q
V
A
S
----
E
------
Q
R
L
A
A
---
C
D
A
V
A
D
V
A
R
A
V
HGIDHRGCP-F--D
R
------
R
----
L
R
V
TIPRA
K
------
E
A
C
------
L
F
A
E
-
I
RS--RD--------
P
----
M
A
----
K
L
---
T
S
L
I
A
K
A
L
---WV-------GR--------E----E
P
V
V
C
HGDLRPD
S
V
L
I
D
A
RT
R
R
V
A
A
V
L
D
V
A
R
LGV
A
------
D
R
Y
T
D
L
A
A
ATR----------GWR---A------G--G-LDKR
V
W
W
RYGE--IP---A
D
A
D
R
V
R
L
Y
R
L
L
A
E
FCLPRPGTGRVEPRQDGG
D
V
R
R
C
G
F
V
R
Q
LGHGVPGDP
T
V
F
H
QRR
G
L
V
V
L
E
T
F
T
R
Q
V
RGGGVDT-GQEIGFGG
F
E
HLAL
P
A
H
R
HRHVDGTRRPLARGQAGFLGQFAPGGLRGRLTGF
D
-
A
A
AGRL
P
Q
QVGVDGVTPAQHQDP
V
V
G
V
Q
AQH
A
G
T
L
T
I
DFGH
D
A
Q
V
M
A
R
RRGG
A
L
AWAPGCPCHRVRCGSC
26
HHSearch
78.53
39%
-18
- C- -
-
4H05
-
?
A:
[7-266]
----------
A
L
R
G
R
Y
P
G
C
-------
E
W
V
V
V
E
----
D
G
A
S
G
A
G
V
Y
R
L
----
R
G
G
-
G
--
R
E
---
L
F
V
K
V
---
A
A
L
G
------
A
G
V
G
L
L
G
E
A
E
R
L
V
W
-
L
A
E
V
-
G
I
P
V
P
R
V
V
E
G
---
G
G
D
-
E
R
V
A
W
----
L
V
T
-
E
-----
A
V
P
---
G
R
------------
P
A
S
A
----
R
WPRE--
Q
R
L
D
V
---
A
V
A
L
A
G
L
A
R
S
L
H
A
L
D
W
E
R
C
P
-
F
--
D
R
------
S
----
L
A
V
T
V
P
Q
A
A
------
R
A
V
------
A
E
G
S
-
V
D
L
--
E
D
--------
L
----
D
E
----
E
R
KGW
S
G
E
R
L
L
A
E
---
L
E
R
T
RP---
A
D
--------
E
----
D
L
A
V
C
H
G
D
L
C
P
D
N
V
L
L
D
P
R
T
C
E
V
T
G
L
I
D
V
G
R
V
G
R
A
------
D
R
H
S
D
L
A
L
V
L
R
----------
E
L
A
---
H
EEDPWF
G
--
P
E
C
S
A
A
F
L
R
E
Y
G
R
--
G
W
D
G
A
V
S
E
E
K
L
A
F
Y
R
L
L
D
E
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
77.59
39%
-18
- C- -
-
4H05
-
?
B:
[7-266]
----------
A
L
R
G
R
Y
P
G
C
-------
E
W
V
V
V
E
----
D
G
A
S
G
A
G
V
Y
R
L
----
R
G
G
-
G
--
R
E
---
L
F
V
K
V
---
A
A
L
G
------
A
G
V
G
L
L
G
E
A
E
R
L
V
W
-
L
A
E
V
-
G
I
P
V
P
R
V
V
E
G
---
G
G
D
-
E
R
V
A
W
----
L
V
T
-
E
-----
A
V
P
---
G
R
------------
P
A
S
A
----
R
WPRE--
Q
R
L
D
V
---
A
V
A
L
A
G
L
A
R
S
L
H
A
L
D
W
E
R
C
P
-
F
--
D
R
------
S
----
L
A
V
T
V
P
Q
A
A
------
R
A
V
------
A
E
G
S
-
V
D
L
--
E
D
--------
L
----
D
E
----
E
R
KGW
S
G
E
R
L
L
A
E
---
L
E
R
T
RP---
A
D
--------
E
----
D
L
A
V
C
H
G
D
L
C
P
D
N
V
L
L
D
P
R
T
C
E
V
T
G
L
I
D
V
G
R
V
G
R
A
------
D
R
H
S
D
L
A
L
V
L
R
----------
E
L
A
---
H
EEDPWF
G
--
P
E
C
S
A
A
F
L
R
E
Y
G
R
--
G
W
D
G
A
V
S
E
E
K
L
A
F
Y
R
L
L
D
E
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
73.90
36%
-10
- C- -
-
4H05
-
?
A:
[7-266]
----------
A
L
R
G
R
Y
P
G
C
-------
E
W
V
V
V
E
--
D
G
A
S
G
A
G
V
--
Y
R
L
----
R
-
G
-
G
--
G
R
E
--
L
F
V
K
V
---
A
A
----
L
G
--
A
G
V
G
L
L
G
E
A
E
R
L
V
W
-
L
A
E
V
-
G
I
P
V
P
R
V
V
E
G
---
G
---
G
D
E
R
------
V
A
-
W
-
L
V
T
E
A
V
P
---
G
R
------------
P
A
S
A
RWPR
E
------
Q
R
L
D
V
---
A
V
A
L
A
G
L
A
R
S
L
H
A
L
D
W
E
R
C
P
-
F
--
D
R
------
S
----
L
A
V
T
V
P
Q
A
A
------
R
A
V
------
A
E
G
S
-
V
D
L
--
E
D
--------
L
----
D
E
----
E
R
---
K
G
W
S
G
E
R
L
---
L
A
E
L
E
R
T
RP
A
D
--------
E
----
D
L
A
V
C
H
G
D
L
C
P
D
N
V
L
L
D
P
R
T
C
E
V
T
G
L
I
D
V
G
R
V
G
R
A
------
D
R
H
S
D
L
A
L
V
L
R
E
L
A
HEEDPWF
G
P
E
---
C
------
S
--
A
-
A
F
L
R
E
Y
G
R
G
W
D
--
G
A
---
V
S
E
E
K
L
A
F
Y
R
L
L
D
E
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
Fugue
72.64
16%
-12
- C7 -
-
5HIU
-
?
A:
[21-460]
---
S
P
E
Q
A
D
L
V
A
K
L
K
N
G
H
L
-------
S
E
R
V
L
A
--
A
N
K
L
R
F
A
V
V
D
F
P
L
----
N
-------
P
---
V
H
A
I
W
---
H
A
A
K
D
M
I
H
--
P
E
N
P
--
D
N
A
R
Q
A
S
W
E
L
L
I
E
-
C
V
K
Y
P
---
N
S
---
T
E
L
-
E
R
S
E
Y
----
F
H
T
-
L
-
T
G
----
P
---
A
H
------------
S
K
D
F
----
C
------
Y
Q
L
V
A
---
L
E
Q
L
T
N
H
G
R
N
I
A
G
F
Y
Y
E
M
F
P
L
L
--
T
L
------
W
----
L
N
Q
A
Y
R
A
A
R
------
D
A
R
------
K
L
A
L
-
A
R
P
--
A
S
--------
P
E
D
K
N
L
S
----
Q
L
---
F
A
L
V
K
D
V
I
---
K
F
-------
N
F
--------
K
FAT
D
D
V
I
A
G
L
I
D
M
L
L
K
I
C
M
L
T
S
V
E
D
D
L
R
A
C
I
H
V
I
E
S
L
V
T
F
G
S
I
P
T
N
K
L
K
Y
C
I
Q
V
L
S
----------
S
I
H
---
C
LV----
P
--
S
-
L
Q
K
E
A
W
H
T
I
S
I
--
I
C
---
R
S
H
H
G
Q
S
T
V
R
I
L
L
D
F
L
R
S
Y
S
------
P
N
P
D
---------------
K
N
R
E
K
D
T
V
R
D
V
R
G
A
L
S
V
L
Q
K
L
L
R
K
T
A
E
K
G
Y
P
Q
V
P
L
S
L
L
V
G
G
L
A
N
V
S
K
S
---------
S
S
T
R
V
A
T
E
I
L
R
L
I
N
S
L
F
H
G
N
I
N
P
I
L
V
E
E
H
W
E
P
I
F
D
V
A
A
Q
C
A
T
K
A
P
T
V
A
K
----------
E
N
V
S
L
Q
L
K
H
L
I
L
R
V
E
N
L
I
V
H
Q
G
P
E
L
L
Q
R
D
D
C
M
K
F
L
I
R
V
Q
H
-
59
SP3
70.01
16%
-61
* C6 *
-
1ND4
1
KKA2_KLEPN
A:
[10-264]
------
G
S
P
A
A
W
V
E
R
L
F
G
Y
-------
D
W
A
Q
Q
T
--
I
G
C
S
D
A
A
V
F
R
L
S
A
----
Q
-
G
-
R
--
P
V
---
L
F
V
K
T
---
D
L
S
G
A
------
L
N
E
L
Q
D
E
A
A
R
L
S
W
-
L
A
T
T
-
G
V
P
C
A
A
V
L
D
V
---
V
T
E
-
A
G
R
D
W
----
L
L
L
-
G
-
E
V
P
G
Q
D
L
---
L
S
------------
S
H
L
A
------------
P
A
E
K
---
V
S
I
M
A
D
A
M
R
R
L
H
T
L
D
P
A
T
C
P
-
F
--
D
H
------
Q
----
A
K
H
R
I
E
R
A
R
------
T
R
M
------
E
A
G
L
-
V
D
Q
--
D
D
LDEEHQGL
A
----
P
A
----
E
L
---
F
A
R
L
K
A
R
M
---
P
D
-------
G
E
-------------
D
L
V
V
T
H
G
D
A
C
L
P
N
I
M
V
E
--
N
G
R
F
S
G
F
I
D
C
G
R
L
G
V
A
------
D
R
Y
Q
D
I
A
L
A
T
R
----------
D
I
A
E
E
L
G
------
G
--
E
-
W
A
D
R
F
L
V
L
Y
G
I
--
A
A
---
P
D
S
Q
R
I
A
F
Y
R
L
L
D
E
F
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
67.94
26%
-24
- C6 -
-
4GKI
1
?
C:
[16-271]
-------
L
N
S
N
L
D
A
D
L
Y
G
Y
-------
R
W
A
R
D
N
----
V
G
Q
S
G
A
T
I
Y
R
L
----
Y
G
K
-
P
NA
P
E
---
L
F
L
K
H
---
G
K
G
S
------
V
A
N
D
V
T
D
E
M
V
R
L
N
W
-
L
T
A
--
F
M
P
L
P
T
I
K
H
F
---
I
R
T
-
P
D
D
A
W
----
L
L
T
-
T
-----
A
I
P
---
G
K
------------
T
A
F
Q
----
V
LEEYPD
S
G
E
N
I
---
V
D
A
L
A
V
F
L
R
R
L
H
S
I
P
V
C
N
C
P
-
F
--
N
S
------
D
RVFR
L
A
Q
A
Q
S
R
M
N
------
N
G
L
------
V
D
A
S
D
F
D
D
--
E
R
--------
N
----
G
-----
W
P
---
V
E
Q
V
W
K
E
M
---
H
K
LLP----
F
S
--------
P
----
D
S
V
V
T
H
G
D
F
S
L
D
N
L
I
F
D
E
G
--
K
L
I
G
C
I
D
V
G
R
V
G
I
A
------
D
R
Y
Q
D
L
A
I
L
W
N
----------
C
L
G
---
E
F-----
S
P-
S
-
L
Q
K
R
L
F
Q
K
Y
G
I
--
D
N
---
P
D
M
N
K
L
Q
F
H
L
M
L
D
E
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
67.92
26%
-26
- C6 -
-
4GKH
2
?
A:
[19-271]
----------
N
L
D
A
D
L
Y
G
Y
-------
R
W
A
R
D
N
----
V
G
Q
S
G
A
T
I
Y
R
L
----
Y
G
K
-
P
N
A
P
E
---
L
F
L
K
H
---
G
K
G
S
------
V
A
N
D
V
T
D
E
M
V
R
L
N
W
-
L
T
A
--
F
M
P
L
P
T
I
K
H
F
---
I
R
T
-
P
D
D
A
W
----
L
L
T
-
T
-----
A
I
P
---
G
K
------------
T
A
F
Q
----
V
L
E
E
Y
P
D
S
G
E
N
I
---
V
D
A
L
A
V
F
L
R
R
L
H
S
I
P
V
C
N
C
P
-
F
--
N
S
------
D
R
V
F
R
L
A
Q
A
Q
S
R
M
N
------
N
G
L
------
V
D
A
S
D
F
D
D
--
E
R
--------
N
----
G
-----
W
P
---
V
E
Q
V
W
K
E
M
---
H
K
L
L
P
----
F
S
--------
P
----
D
S
V
V
T
H
G
D
F
S
L
D
N
L
I
F
D
E
G
--
K
L
I
G
C
I
D
V
G
R
V
G
I
A
------
D
R
Y
Q
D
L
A
I
L
W
N
----------
C
L
G
---
E
F-----
S
P
-
S
-
L
Q
K
R
L
F
Q
K
Y
G
I
--
D
N
---
P
D
M
N
K
L
Q
F
H
L
M
L
D
E
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
Fugue
67.79
19%
-30
- C6 -
-
1J7L
1
KKA3_ENTFL
A:
[2-264]
---
A
K
M
R
I
S
P
E
L
K
K
L
I
E
K
Y
-------
R
C
V
K
D
T
--
E
G
M
S
--
P
A
K
V
Y
K
L
----
V
-
G
-
E
--
N
E
---
N
L
Y
L
K
---
M
T
D
S
R
Y
K
G
--
T
T
Y
D
V
E
R
E
K
D
M
M
L
W
-
L
E
G
K
--
L
P
V
P
K
V
L
H
F
---
E
R
H
-
D
G
W
S
N
----
L
L
M
-
S
E
A
D
G
V
L
C
S
---
E
E
------------
Y
E
D
E
----
Q
------
S
P
E
K
I
---
I
E
L
Y
A
E
C
I
R
L
F
H
S
I
D
I
S
D
C
P
-
Y
--
T
N
------
S
----
L
D
S
R
L
A
E
L
D
------
Y
L
L
N
N
DLAD
V
D
C
E
-
N
W
E
--
E
D
--------
T
----
P
F
----
K
D
---
P
R
E
L
Y
D
F
L
---
K
T
-------
E
K
P
E
------
E
----
E
L
V
F
S
H
G
D
L
G
D
S
N
I
F
V
K
--
D
G
K
V
S
G
F
I
D
L
G
R
S
G
R
A
------
D
K
W
Y
D
I
A
F
C
V
R
----------
S
I
R
---
E
D
IG---
E
--
E
-
Q
Y
V
E
L
F
F
D
L
L
G
--
I
K
---
P
D
W
E
K
I
K
Y
Y
I
L
L
D
E
L
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
65.83
29%
-12
- C6 -
-
1ND4
1
KKA2_KLEPN
A:
[11-263]
------
S
P
A
A
W
V
E
R
L
F
G
Y
D
--------
W
A
Q
Q
T
----
I
G
C
S
D
A
A
V
F
R
L
----
S
A
Q
G
R
--
P
V
---
L
F
V
K
T
---
D
L
S
G
------
A
L
N
E
L
Q
D
E
A
A
R
L
S
W
-
L
A
T
T
-
G
V
P
C
A
A
V
L
D
V
---
V
T
E
-
A
G
R
D
W
----
L
L
L
-
G
-----
E
V
P
---
G
Q
------------
D
L
L
S
----
S
HL----
A
P
A
E
K
---
V
S
I
M
A
D
A
M
R
R
L
H
T
L
D
P
A
T
C
P
-
F
--
D
H
------
Q
----
A
K
H
R
I
E
R
A
R
------
T
R
M
------
E
A
G
L
-
V
D
Q
--
D
D
--------
L
----
D
E
EHQG
L
A
---
P
A
E
L
F
A
R
L
---
K
A
R
MP----
D
G
--------
E
----
D
L
V
V
T
H
G
D
A
C
L
P
N
I
M
V
E
N
G
--
R
F
S
G
F
I
D
C
G
R
L
G
V
A
------
D
R
Y
Q
D
I
A
L
A
T
R
----------
D
I
A
E
E
-
L
------
G
G
-
E
-
W
A
D
R
F
L
V
L
Y
G
I
--
A
A
---
P
D
S
Q
R
I
A
F
Y
R
L
L
D
E
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
65.68
28%
1
- C6 -
-
4FEU
2
?
A:
[27-271]
------------------
Y
-------
R
W
A
R
D
N
--
V
G
Q
S
--
G
A
T
I
Y
R
L
----
Y
-
G
-
K
--
P
N
A
P
E
L
F
L
K
H
G
K
G
S
V
A
N
D
V
T
D
--
E
-------
M
V
R
L
N
W
-
L
T
A
F
-
M
-
P
L
P
T
I
K
H
F
---
I
R
T
-
P
D
D
A
W
----
L
L
T
-
T
-----
A
I
P
G
KT
A
F
------------
Q
V
L
E
----
E
------
Y
P
D
S
G
E
N
I
V
D
A
L
A
V
F
L
R
R
L
H
S
I
P
V
C
N
C
P
-
F
NS
D
R
------
V
----
F
R
L
A
Q
A
Q
S
R
M
N
N
GLV
D
A
S
------
D
F
D
D
-
E
R
N
--
G
W
--------
P
----
V
E
----
Q
V
---
W
K
E
M
H
K
L
L
---
P
F
-------
S
---------
P
----
D
S
V
V
T
H
G
D
F
S
L
D
N
L
I
F
D
E
G
--
K
L
I
G
C
I
D
V
G
R
V
G
I
A
------
D
R
Y
Q
D
L
A
I
L
W
N
C
L
--------
G
E
F
---
S
------
P
--
S
-
L
Q
K
R
L
F
Q
K
Y
G
I
--
D
N
---
P
D
M
N
K
L
Q
F
H
L
M
L
D
E
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
64.98
28%
7
- C6 -
-
4EJ7
2
?
A:
[47-291]
------------------
Y
-------
R
W
A
R
D
N
--
V
G
Q
S
--
G
A
T
I
Y
R
L
----
Y
-
G
-
K
--
P
N
A
P
E
L
F
L
K
H
G
K
G
S
V
A
N
D
V
T
D
--
E
-------
M
V
R
L
N
W
-
L
T
A
F
-
M
-
P
L
P
T
I
K
H
F
---
I
R
T
-
P
D
D
A
W
----
L
L
T
-
T
-----
A
I
P
G
KT
A
F
------------
Q
V
L
E
----
E
------
Y
P
D
S
G
E
N
I
V
D
A
L
A
V
F
L
R
R
L
H
S
I
P
V
C
N
C
P
-
F
NS
D
R
------
V
----
F
R
L
A
Q
A
Q
S
R
M
N
N
GLV
D
A
S
------
D
F
D
D
-
E
R
N
--
G
W
--------
P
----
V
E
----
Q
V
---
W
K
E
M
H
K
L
L
---
P
F
-------
S
---------
P
----
D
S
V
V
T
H
G
D
F
S
L
D
N
L
I
F
D
E
G
--
K
L
I
G
C
I
D
V
G
R
V
G
I
A
------
D
R
Y
Q
D
L
A
I
L
W
N
C
L
--------
G
E
F
---
S
------
P
--
S
-
L
Q
K
R
L
F
Q
K
Y
G
I
--
D
N
---
P
D
M
N
K
L
Q
F
H
L
M
L
D
E
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
63.96
28%
10
- C6 -
-
4FEV
2
?
A:
[27-271]
------------------
Y
-------
R
W
A
R
D
N
--
V
G
Q
S
--
G
A
T
I
Y
R
L
----
Y
-
G
-
K
--
P
N
A
P
E
L
F
L
K
H
G
K
G
S
V
A
N
D
V
T
D
--
E
-------
M
V
R
L
N
W
-
L
T
A
F
--
M
P
L
P
T
I
K
H
F
---
I
R
T
-
P
D
D
A
W
----
L
L
T
-
T
-----
A
I
P
GKT
A
F
------------
Q
V
L
E
----
E
------
Y
P
D
S
G
E
N
I
V
D
A
L
A
V
F
L
R
R
L
H
S
I
P
V
C
N
C
P
-
F
NS
D
R
------
V
----
F
R
L
A
Q
A
Q
S
R
M
N
N
GLV
D
A
S
------
D
F
D
D
-
E
R
N
--
G
W
--------
P
----
V
E
----
Q
V
---
W
K
E
M
H
K
L
L
---
P
F
-------
S
---------
P
----
D
S
V
V
T
H
G
D
F
S
L
D
N
L
I
F
D
E
G
--
K
L
I
G
C
I
D
V
G
R
V
G
I
A
------
D
R
Y
Q
D
L
A
I
L
W
N
C
L
--------
G
E
F
---
S
------
P
--
S
-
L
Q
K
R
L
F
Q
K
Y
G
I
--
D
N
---
P
D
M
N
K
L
Q
F
H
L
M
L
D
E
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
63.73
28%
6
- C6 -
-
4FEX
3
?
A:
[27-271]
------------------
Y
-------
R
W
A
R
D
N
--
V
G
Q
S
--
G
A
T
I
Y
R
L
----
Y
-
G
-
K
--
P
N
A
P
E
L
F
L
K
H
G
K
G
S
V
A
N
D
V
T
D
--
E
-------
M
V
R
L
N
W
-
L
T
A
F
--
M
P
L
P
T
I
K
H
F
---
I
R
T
-
P
D
D
A
W
----
L
L
T
-
T
-----
A
I
P
G
KT
A
F
------------
Q
V
L
E
----
E
------
Y
P
D
S
G
E
N
I
V
D
A
L
A
V
F
L
R
R
L
H
S
I
P
V
C
N
C
P
-
F
NS
D
R
------
V
----
F
R
L
A
Q
A
Q
S
R
M
N
N
GLV
D
A
S
------
D
F
D
D
-
E
R
N
--
G
W
--------
P
----
V
E
----
Q
V
---
W
K
E
M
H
K
L
L
---
P
F
-------
S
---------
P
----
D
S
V
V
T
H
G
D
F
S
L
D
N
L
I
F
D
E
G
--
K
L
I
G
C
I
D
V
G
R
V
G
I
A
------
D
R
Y
Q
D
L
A
I
L
W
N
C
L
--------
G
E
F
---
S
------
P
--
S
-
L
Q
K
R
L
F
Q
K
Y
G
I
--
D
N
---
P
D
M
N
K
L
Q
F
H
L
M
L
D
E
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
Fugue
63.65
15%
-27
- C6 -
-
3ATS
1
Y3168_MYCTU
A:
[1-357]
--
T
L
P
A
V
I
S
R
W
L
S
S
V
L
P
G
G
AA
P
E
V
T
V
E
S
G
V
D
S
TG
M
S
S
E
T
I
I
L
T
A
R
W
Q
Q
DG
R
S
-
I
-
Q
--
Q
K
---
L
V
A
R
V
---
A
P
A
A
E
D
V
P
VF
P
T
Y
R
L
D
H
Q
F
E
V
I
R
L
-
V
G
E
L
T
D
V
P
V
P
R
V
R
W
I
ETT
G
D
V
-
L
G
T
P
F
----
F
L
M
-
D
-
Y
V
E
G
V
V
P
---
P
D
VMPYTFGDNWFA
D
A
P
A
----
E
------
R
Q
R
Q
L
---
Q
D
A
T
V
A
A
L
A
T
L
H
S
I
P
N
A
Q
N
T
-
F
--
S
F
LTDT
T
L
H
----
R
H
F
N
W
V
R
S
W
------
Y
D
F
------
A
V
E
G
-
I
G
R
--
S
P
--------
L
----
L
E
----
R
T
---
F
E
W
L
Q
S
H
W
P
D
-
D
A
-------
A
A
--------
R
----
E
P
V
L
L
W
G
D
A
R
V
G
N
V
L
Y
R
D
F
--
Q
P
V
A
V
L
D
W
E
M
V
A
L
G
------
P
R
E
L
D
V
A
W
M
I
F
----------
A
H
R
---
V
------
F
--
Q
-
E
L
A
G
L
A
T
L
P
G
L
PE
V
M
---
R
E
D
D
V
R
A
T
Y
Q
A
L
T
G
V
E
L
G
D
----------------------------------------------------------------
L
H
W
F
Y
V
Y
S
G
V
M
W
A
C
V
F
M
R
T
G
A
R
R
V
H
F
G
E
I
E
--------------------------------------------------
K
P
D
D
V
E
S
L
F
Y
H
A
G
L
M
K
H
L
L
G
E
E
H
----------------
7
PsiBlast_PDB
63.08
28%
9
- C6 -
-
4FEW
2
?
A:
[27-271]
------------------
Y
-------
R
W
A
R
D
N
--
V
G
Q
S
--
G
A
T
I
Y
R
L
----
Y
-
G
-
K
--
P
N
A
P
E
L
F
L
K
H
G
K
G
S
V
A
N
D
V
T
D
--
E
-------
M
V
R
L
N
W
-
L
T
A
F
-
M
-
P
L
P
T
I
K
H
F
---
I
R
T
-
P
D
D
A
W
----
L
L
T
-
T
-----
A
I
P
GKT
A
F
------------
Q
V
L
E
----
E
------
Y
P
D
S
G
E
N
I
V
D
A
L
A
V
F
L
R
R
L
H
S
I
P
V
C
N
C
P
-
F
NS
D
R
------
V
----
F
R
L
A
Q
A
Q
S
R
M
N
N
GLV
D
A
S
------
D
F
D
D
-
E
R
N
--
G
W
--------
P
----
V
E
----
Q
V
---
W
K
E
M
H
K
L
L
---
P
F
-------
S
---------
P
----
D
S
V
V
T
H
G
D
F
S
L
D
N
L
I
F
D
E
G
--
K
L
I
G
C
I
D
V
G
R
V
G
I
A
------
D
R
Y
Q
D
L
A
I
L
W
N
C
L
--------
G
E
F
---
S
------
P
--
S
-
L
Q
K
R
L
F
Q
K
Y
G
I
--
D
N
---
P
D
M
N
K
L
Q
F
H
L
M
L
D
E
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
62.56
28%
15
- C6 -
-
4GKI
3
?
A:
[27-271]
------------------
Y
-------
R
W
A
R
D
N
--
V
G
Q
S
--
G
A
T
I
Y
R
L
----
Y
-
G
-
K
--
P
N
A
P
E
L
F
L
K
H
G
K
G
S
V
A
N
D
V
T
D
--
E
-------
M
V
R
L
N
W
-
L
T
A
F
-
M
-
P
L
P
T
I
K
H
F
---
I
R
T
-
P
D
D
A
W
----
L
L
T
-
T
-----
A
I
P
G
KT
A
F
------------
Q
V
L
E
----
E
------
Y
P
D
S
G
E
N
I
V
D
A
L
A
V
F
L
R
R
L
H
S
I
P
V
C
N
C
P
-
F
NS
D
R
------
V
----
F
R
L
A
Q
A
Q
S
R
M
N
N
GLV
D
A
S
------
D
F
D
D
-
E
R
N
--
G
W
--------
P
----
V
E
----
Q
V
---
W
K
E
M
H
K
L
L
---
P
F
-------
S
---------
P
----
D
S
V
V
T
H
G
D
F
S
L
D
N
L
I
F
D
E
G
--
K
L
I
G
C
I
D
V
G
R
V
G
I
A
------
D
R
Y
Q
D
L
A
I
L
W
N
C
L
--------
G
E
F
---
S
------
P
--
S
-
L
Q
K
R
L
F
Q
K
Y
G
I
--
D
N
---
P
D
M
N
K
L
Q
F
H
L
M
L
D
E
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
62.23
21%
-9
- C6 -
-
1L8T
2
KKA3_ENTFL
A:
[4-262]
------
R
I
S
P
E
L
K
K
L
I
E
K
Y
-------
R
C
V
K
D
T
----
E
G
M
S
P
A
K
V
Y
K
L
----
V
G
E
-
N
--
E
N
---
L
Y
L
K
M
---
T
D
S
R
Y
-
K
G
--
T
T
Y
D
V
E
R
E
K
D
M
M
L
W
-
L
E
G
--
K
L
P
V
P
K
V
L
H
F
---
E
R
H
-
D
G
W
S
N
----
L
L
M
-
S
-----
E
A
D
---
G
V
------------
L
C
S
E
----
E
Y
E
DEQ-
S
P
E
K
I
---
I
E
L
Y
A
E
C
I
R
L
F
H
S
I
D
I
S
D
C
P
-
Y
--
T
N
------
S
----
L
D
S
R
L
A
E
L
D
------
Y
L
L
------
N
N
D
L
-
A
D
V
DC
E
N
--------
W
----
E
E
----
D
T
---
P
F
K
D
P
R
E
L
Y
D
F
L
K
T
E
K----
P
E
--------
E
----
E
L
V
F
S
H
G
D
L
G
D
S
N
I
F
V
K
D
G
--
K
V
S
G
F
I
D
L
G
R
S
G
R
A
------
D
K
W
Y
D
I
A
F
C
V
R
----------
S
I
R
---
E
D
I
----
G
E
E
Q
-
Y
V
E
L
F
F
D
L
L
G
I
--
K
----
P
D
W
E
K
I
K
Y
Y
I
L
L
D
E
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
61.99
31%
-33
- C6 -
-
1ND4
1
KKA2_KLEPN
A:
[63-263]
----------------------------------------------------------------------------------------
E
A
A
R
L
S
W
-
L
A
T
T
-
G
V
P
C
A
A
V
L
D
V
---
V
T
E
-
A
G
R
D
W
----
L
L
L
G
E
-
V
P
G
Q
D
L
L
---
S
S
------------
H
L
A
P
----
A
------
E
K
V
S
I
------
M
A
D
A
M
R
R
L
H
T
L
D
P
A
T
C
P
-
F
--
D
H
------
Q
----
A
K
H
R
I
E
R
A
R
------
T
R
-------
M
E
A
G
-
L
V
D
--
Q
D
--------
D
----
L
D
----
E
E
---
H
Q
G
L
A
P
A
E
---
L
F
-------
A
R
L
K
A
R
MPDG
E
----
D
L
V
V
T
H
G
D
A
C
L
P
N
I
M
V
E
--
N
G
R
F
S
G
F
I
D
C
G
R
L
G
V
A
------
D
R
Y
Q
D
I
A
L
A
T
R
----------
D
I
A
E
E
L
G
------
G
--
E
-
W
A
D
R
F
L
V
L
Y
G
I
--
A
A
---
P
D
S
Q
R
I
A
F
Y
R
L
L
D
E
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
61.36
21%
-8
- C6 -
-
3TM0
2
KKA3_ENTFL
A:
[4-262]
------
R
I
S
P
E
L
K
K
L
I
E
K
Y
-------
R
C
V
K
D
T
----
E
G
M
S
P
A
K
V
Y
K
L
----
V
G
E
-
N
--
E
N
---
L
Y
L
K
M
---
T
D
S
R
Y
-
K
G
--
T
T
Y
D
V
E
R
E
K
D
M
M
L
W
-
L
E
G
--
K
L
P
V
P
K
V
L
H
F
---
E
R
H
-
D
G
W
S
N
----
L
L
M
-
S
-----
E
A
D
---
G
V
------------
L
C
S
E
----
E
Y
EDEQ-
S
P
E
K
I
---
I
E
L
Y
A
E
C
I
R
L
F
H
S
I
D
I
S
D
C
P
-
Y
--
T
N
------
S
----
L
D
S
R
L
A
E
L
D
------
Y
L
L
------
N
N
D
L
-
A
D
V
DC
E
N
--------
W
----
E
E
----
D
T
---
P
F
K
D
P
R
E
L
Y
D
F
L
K
T
E
K----
P
E
--------
E
----
E
L
V
F
S
H
G
D
L
G
D
S
N
I
F
V
K
D
G
--
K
V
S
G
F
I
D
L
G
R
S
G
R
A
------
D
K
W
Y
D
I
A
F
C
V
R
----------
S
I
R
---
E
D
I----
G
EE
Q
-
Y
V
E
L
F
F
D
L
L
G
I
--
K
----
P
D
W
E
K
I
K
Y
Y
I
L
L
D
E
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
60.93
28%
14
- C6 -
-
4GKH
2
?
A:
[27-271]
------------------
Y
-------
R
W
A
R
D
N
--
V
G
Q
S
--
G
A
T
I
Y
R
L
----
Y
-
G
-
K
--
P
N
A
P
E
L
F
L
K
H
G
K
G
S
V
A
N
D
V
T
D
--
E
-------
M
V
R
L
N
W
-
L
T
A
F
-
M
-
P
L
P
T
I
K
H
F
---
I
R
T
-
P
D
D
A
W
----
L
L
T
-
T
-----
A
I
P
GKT
A
F
------------
Q
V
L
E
----
E
------
Y
P
D
S
G
E
N
I
V
D
A
L
A
V
F
L
R
R
L
H
S
I
P
V
C
N
C
P
-
F
NS
D
R
------
V
----
F
R
L
A
Q
A
Q
S
R
M
N
N
GLV
D
A
S
------
D
F
D
D
-
E
R
N
--
G
W
--------
P
----
V
E
----
Q
V
---
W
K
E
M
H
K
L
L
---
P
F
-------
S
---------
P
----
D
S
V
V
T
H
G
D
F
S
L
D
N
L
I
F
D
E
G
--
K
L
I
G
C
I
D
V
G
R
V
G
I
A
------
D
R
Y
Q
D
L
A
I
L
W
N
C
L
--------
G
E
F
---
S
------
P
--
S
-
L
Q
K
R
L
F
Q
K
Y
G
I
--
D
N
---
P
D
M
N
K
L
Q
F
H
L
M
L
D
E
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Blastp_CBE
60.62
31%
-31
- C6 -
-
1ND4
1
KKA2_KLEPN
B:
[63-263]
----------------------------------------------------------------------------------------
E
A
A
R
L
S
W
-
L
A
T
T
-
G
V
P
C
A
A
V
L
D
V
---
V
T
E
-
A
G
R
D
W
----
L
L
L
G
E
-
V
P
G
Q
D
L
L
---
S
S
------------
H
L
A
P
----
A
------
E
K
V
S
I
------
M
A
D
A
M
R
R
L
H
T
L
D
P
A
T
C
P
-
F
--
D
H
------
Q
----
A
K
H
R
I
E
R
A
R
------
T
R
-------
M
E
A
G
-
L
V
D
--
Q
D
--------
D
----
L
D
----
E
E
---
H
Q
G
L
A
P
A
E
---
L
F
-------
A
R
LKARMPDG
E
----
D
L
V
V
T
H
G
D
A
C
L
P
N
I
M
V
E
--
N
G
R
F
S
G
F
I
D
C
G
R
L
G
V
A
------
D
R
Y
Q
D
I
A
L
A
T
R
----------
D
I
A
EEL
G
------
G
--
E
-
W
A
D
R
F
L
V
L
Y
G
I
--
A
A
---
P
D
S
Q
R
I
A
F
Y
R
L
L
D
E
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
41.75
18%
-12
- C6 -
-
5IGI
3
?
A:
[31-254]
------------------------------------
E
L
G
L
D
Y
R
I
V
I
A
----
T
V
D
D
G
--
R
R
---
W
V
L
R
I
---
P
R
R
A
---
E
--
V
S
A
K
V
E
P
E
A
R
V
L
A
M
-
L
K
N
R
L
P
F
A
V
P
D
W
R
V
A
---
N
A
E
L
V
A
Y
P
M
LEDS
T
A
--
V
-----
I
Q
P
---
G
S
------------
S
T
P
D
----
W
VVPQ--
D
S
E
V
F
---
A
E
S
F
A
T
A
L
A
A
L
H
A
V
P
I
S
A
A
V
-
D
--
A
G
MLIR--
T
----
P
T
Q
A
R
Q
K
V
A
------
D
D
V
------
D
R
V
R
-
R
E
F
------------
V
----
V
N
----
D
K
---
R
L
H
R
W
Q
R
W
---
L
D
DDSS---
W
P
--------
D
----
F
S
V
V
V
H
G
D
L
Y
V
G
H
V
L
I
D
N
T
E
-
R
V
S
G
M
I
D
W
S
E
A
R
V
D
------
D
P
A
I
D
M
A
A
H
L
M
----------
V
F
G
---
E
---------
E
-
G
L
A
K
L
L
L
T
Y
E
A
--
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------