@TOME V3
(Feb 2022)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : G17_092570T0_kcl54: (2019-03-29 )
PQPSDGLRRTWEEARENDCEVRIFSDKVNKYIQPLDRFFITPGLETHYIINAGGVQYPVSFLAPKGCEAAITGKLPPTYGV
Atome Classification :
(20 SA)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10.......---------.20...---...-----.--.30....-.-...-40------------...---.-------...--..50...---..-..-----.60.-..--.----.---...70.--..-.....80-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQP
S
D
G
L
R
R
T
W
E
E
A
REND---------C
E
V
R
I
F
---
S
D
K
-----
V
--
N
K
Y
I
Q
P
L
-
D
-
R
F
F-I-------------TPG---L-------
E
T
H
--
Y
I
I
NAGG---VQ-Y
P
-----
V
S
FL-AP--K----G---CE
A
A
IT--GK-LPPTYGV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
SP3
66.66
20%
31
- C2 -
0.25
1VZW
1
HIS4_STRCO
A:
[2-240]
------------------------------------------------------------------S
K
L
E
L
L
P
A
V
D
V
R
DGQAVRETSYGS
P
L
E
A
A
L
A
W
Q
R
S
GAE
W
L
H
L
V
D
L
D
A
A
F
GTGDN
R
A
L
I
A
E
V
A
Q
A
MD
I
K
V
E
L
S
G
GIRD
D
D
T
L
A
A
A
L
A
T
GCT
R
V
N
L
G
T
A
A
L
E
T
P
E
W
V
A
K
V
I
A
E
HGDK
I
A
V
G
L
D
V
RGT
T
L
R
G
RGW
T
R
D
G
G
D
L
Y
E
T
L
D
R
L
N
K
E
G
---------
C
A
R
Y
V
V
---
T
D
------
I
--
G
P
N
L
E
L
L
-
K
-
N
V
C
-----------------
A
---
A
-------
T
D
R
--
P
V
V
A
S
G
G
---
V
S
-
S
L
D
D
L
R
A
I
A
G
L
-
V
P
--
A
----
G
---
V
E
G
A
I
V
--
G
K
A
L
--
Y
A
K
A
FT
L
E
E
A
L
E
A
T
S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
Fugue
58.52
20%
52
- C3 -
-
2E6Q
-
A:
[1-112]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GSSG
S
S
G
T
A
R
L
V
A
G
L
E
D
V
Q
V
Y
D
---------
G
E
D
A
V
F
---
S
L
D
-----
L
--
S
T
I
I
Q
G
----
T
W
F
-
L
NG
E
E
L
K
SN
E
P
E
G
Q
V
E
P
---
G
-------
A
L
R
--
Y
R
I
E
Q
K
G
---
L
Q
-
H
R
-----
L
I
L
H
-
A
V
--
K
HQDS
G
---
A
L
V
G
F
S
--
C
P
-
G
V
Q
D
S
A
A
L
T
I
Q
E
SSGPSSG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
57.47
15%
-11
- C2 -
0.40
4R80
-
?
A:
[1-76]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
S
E
E
E
E
K
R
R
A
K
Q
V
A
K
E
--------------
K
I
L
---
E
Q
N
-----
P
--
S
S
K
V
Q
V
R
-
R
-
V
Q
K
-
Q
-------------
G
N
T
---
I
-------
R
V
E
--
L
E
I
T
E
N
G
---
K
K
-
T
N
-----
I
T
V
E
-
V
E
--
K
----
Q
---
G
N
T
F
T
V
--
K
R
-
I
T
E
T
V
G
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
Fugue
54.41
26%
47
- C2 -
0.06
5ISE
6
CARM1_MOUSE
A:
[10-352]
-------------------S
V
F
S
E
R
T
E
E
S
S
A
V
Q
Y
F
Q
F
Y
GY
L
S
Q
Q
Q
N
M
M
Q
DYV
R
T
G
T
Y
Q
R
A
I
L
Q
N
HTDFKD
K
I
V
L
D
V
GCGSG
I
L
S
F
F
A
A
Q
A
GAR
K
I
Y
A
V
E
ASTM
A
Q
H
A
E
V
L
V
K
S
N
NLTDR
I
V
V
I
P
G
KVEEVSLPEQVD
I
I
I
S
EPMGYMLFNER
M
L
E
S
Y
L
H
A
KKYLKPSGNMFPT
I
G
D
V
H
L
A
P
F
T
D
E
Q
L
Y
M
E
Q
F
T
K
A
N
F
W
Y
Q
P
S
F
H
G
V
-----------------------------
D
L
-----
S
--
A
L
R
G
A
A
V
-
D
-
E
Y
F
-
R
-------------
Q
P
V
---
V
-------
D
T
F
D
I
R
I
L
M
A
K
S
---
V
K
-
Y
T
-----
V
N
F
L
-
E
A
--
K
----
E
---
G
D
L
H
-
R
--
I
E
-
I
P
F
K
F
H
M
L
H
S
G
L
V
H
G
L
A
F
W
F
D
V
A
FIGSI
M
T
V
W
L
S
TAPTEPLTHWY
Q
V
R
C
L
F
Q
S
P
L
F
A
K
AG
D
T
L
S
G
T
C
L
L
I
A
N
KRQSYD
I
S
I
V
A
Q
VDQTG
S
K
S
S
N
L
L
D
LKNPFFRYT--------------------------------------------------------------------------------------------------------------------------------------------------------------
50
Fugue
54.25
26%
47
- C2 -
0.12
5IH3
7
CARM1_MOUSE
A:
[10-352]
-------------------S
V
F
S
E
R
T
E
E
S
S
A
V
Q
Y
F
Q
F
Y
G
Y
L
S
Q
Q
Q
N
M
M
Q
DYV
R
T
G
T
Y
Q
R
A
I
L
Q
N
HTDFKD
K
I
V
L
D
V
GCGSG
I
L
S
F
F
A
A
Q
A
GAR
K
I
Y
A
V
E
ASTM
A
Q
H
A
E
V
L
V
K
S
N
NLTDR
I
V
V
I
P
G
KVEEVSLPEQVD
I
I
I
S
EPMGYMLFNER
M
L
E
S
Y
L
H
A
KKYLKPSGNMFPT
I
G
D
V
H
L
A
P
F
T
D
E
Q
L
Y
M
E
Q
F
T
K
A
N
F
W
Y
Q
P
S
F
H
G
V
-----------------------------
D
L
-----
S
--
A
L
R
G
A
A
V
-
D
-
E
Y
F
-
R
-------------
Q
P
V
---
V
-------
D
T
F
D
I
R
I
L
M
A
K
S
---
V
K
-
Y
T
-----
V
N
F
L
-
E
A
--
K
----
E
---
G
D
L
H
-
R
--
I
E
-
I
P
F
K
F
H
M
L
H
S
G
L
V
H
G
L
A
F
W
F
D
V
A
FIGSI
M
T
V
W
L
S
TAPTEPLTHWY
Q
V
R
C
L
F
Q
S
P
L
F
A
K
AG
D
T
L
S
G
T
C
L
L
I
A
N
KRQ
S
Y
D
I
S
I
V
A
Q
VDQTG
S
K
S
S
N
L
L
D
LKNPFFRYT--------------------------------------------------------------------------------------------------------------------------------------------------------------
36
SP3
52.90
17%
-29
- C2 -
0.18
2GSA
2
GSA_SYNP6
A:
[6-432]
------------------------------------------------------------------------------------------------------------FKT
I
K
S
D
E
I
F
A
A
A
Q
K
L
MPGGVSSPVRAFKSV
G
G
Q
P
I
V
F
DRVKDA
Y
A
W
D
VDGNRYIDYVGTWGPAICGHAH
P
E
V
I
E
A
L
K
V
A
M
E
KGTSFGAP
C
A
L
E
N
V
L
A
E
M
V
N
D
A
V
P
S
I
---------
E
M
V
R
F
V
---
N
S
G
-----
T
--
E
A
C
M
A
V
L
-
R
-
L
M
R
-
A
-------------
Y
T
G
-----------
R
D
K
--
I
I
K
F
E
G
C
---
Y
H
-
G
H
-----
A
D
M
F
-
L
V
--
K
----
A
---
G
S
G
V
A
T
--
L
G
-
L
P
S
S
P
G
V
P
K
K
T
T
A
N
T
L
T
T
P
YND
L
E
A
V
K
A
L
F
A
E
N
PGEIA
G
V
I
L
EPIVGNS
G
F
I
V
P
D
AG
F
L
E
G
L
R
E
I
T
L
E
H
D
A
L
L
V
F
DEVMTGFRIAYGG
V
Q
E
K
F
GVTPD
L
T
T
L
G
KIIGGG
L
P
V
G
A
Y
G
G
K
REIMQLVAPAGP
M
Y
Q
A
G
TLSGN
P
L
A
M
T
A
G
I
K
T
L
E
L
L
R
QPG
T
Y
E
Y
L
D
Q
I
T
K
R
L
S
D
G
L
L
A
I
A
Q
E
T
G
H
A
A
C
G
G
Q
V
SG
M
F
G
F
F
FTEGPVHN
Y
E
D
A
K
K
SD
L
Q
K
F
S
R
F
H
R
G
M
L
E
Q
GIYLAPSQF
E
A
G
F
T
S
LAHT
E
E
D
I
D
A
T
L
A
A
A
R
T
V
M
S
A
L
32
SP3
50.32
16%
47
- C2 -
0.33
1WD7
-
?
A:
[8-261]
----------------------------------------A
V
R
V
A
Y
AGLRR
K
E
A
F
K
A
L
A
E
K
L
G
F
T
P
L
L
F
P
VQAT
E
K
V
P
V
PE
Y
R
D
Q
V
R
A
L
A
Q
GVD
L
F
L
A
TT
G
V
G
V
R
D
L
L
E
A
G
K
A
L
GLD
L
E
G
P
L
A
K
A
F
R
L
A
RG
A
K
A
A
R
A
L
K
E
A
GLPPHAVGDGTSKSLLPL
L
P
Q
G
R
G
V
A
A
L
Q
L
YGKPL
P
L
L
E
N
A
L
A
E
R
GYR
V
L
P
L
M
P
Y
R
H
L
P
D
P
E
G
I
L
R
L
E
E
A
L
L
R
G
E
---------
V
D
A
L
A
F
VA-
A
I
Q
-----
V
--
E
F
L
F
E
G
A
K
D
-
P
K
A
-
L
-------------
R
E
A
---
L
-------
N
T
R
--
V
K
A
L
A
V
G
----
R
-
V
T
-----
A
D
A
L
-
R
E
--
W
----
G
---
V
K
P
F
Y
V
------
D
E
T
E
R
L
G
S
L
L
Q
G
F
K
R
A
L
Q
K
E
V
A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
49.13
19%
-29
- C2 -
0.11
5J0H
-
?
A:
[7-78]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Y
E
L
R
R
A
L
E
E
L
E
K
A
L
---------
R
E
L
K
K
S
---
L
D
E
-----
L
--
E
R
S
L
E
E
L
-
E
-
K
N
P
-
S
-------------
E
D
A
---
L
-------
V
E
N
--
N
R
L
N
V
E
N
---
N
K
-
I
I
-----
V
E
V
L
-
R
I
--
I
----
A
---
E
V
L
K
I
N
--
A
K
-
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
SP3
48.81
16%
41
- C2 -
0.32
1ST9
3
RESA_BACSU
A:
[2-138]
--------------------------------------------------------------------------------------------------------------------------------------------------------------EGSDA
P
N
F
V
L
E
D
TNG
K
R
I
E
LSDLKG
K
G
V
F
L
N
F
W
G
TWC
E
P
C
K
K
E
F
P
Y
M
A
N
Q
Y
K
H
F
K
S
Q
G
---------
V
E
I
V
A
V
---
N
-------
V
--
G
E
S
K
I
A
V
-
H
-
N
F
M
-
K
-------------
S
Y
G
---
V
N
F
P
V
V
L
D
T
D
R
--
Q
V
L
D
A
Y
D
---
V
S
P
L
P
-----
T
T
F
L
I
N
P
--
E
----
G
K--
V
V
K
V
V
T
--
G
T
-
M
T
E
S
-
M
I
H
D
Y
M
N
L
I
KP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
48.58
27%
-122
- C4 -
-
4YPO
-
ILVC_MYCTU
A:
[83-129]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
E
I
F
---
A
G
D
-----
I
--
E
P
N
L
K
P
G
-
D
-
A
L
F
-
F
-------------
G
H
G
---
L
-------
N
V
H
--
F
G
L
I
K
P
P
---
A
D
-
V
A
-----
V
A
M
V
-
A
P
--
K
----
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
48.13
22%
-21
- C2 -
0.23
2I9F
2
NCAP_EAVBU
A:
[6-64]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
H
H
E
P
G
D
---------
L
R
H
D
L
N
---
Q
Q
E
-----
R
--
A
T
L
S
S
N
V
-
Q
-
R
F
F
M
I
-------------
G
H
G
-------------
S
--
L
T
A
D
A
G
G
---
L
T
-
Y
T
-----
V
S
W
V
-
P
T
--
K
----
Q
---
I
Q
R
K
V
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
SP3
46.47
14%
43
- C2 -
0.32
1GU7
6
ETR1_CANTR
A:
[1-364]
M
I
T
A
Q
A
V
L
Y
TQHGEPKDV
L
F
T
Q
S
F
E
I
D
DDNLAPN
E
V
I
V
K
T
L
G
S
P
V
N
P
S
D
I
N
Q
I
Q
GVYP
S
K
P
A
K
T
TGFGTT
E
P
A
A
P
C
G
N
E
G
L
F
E
V
IKVGSNVSSLEAG
D
W
V
I
P
SHVNFGTWRT
H
A
L
G
N
DDD
F
I
K
L
PN
P
A
Q
S
K
A
N
GKPNGLT
I
N
Q
G
A
T
ISV
N
P
L
T
A
Y
L
M
L
TH
Y
V
K
L
T
P
G
K
D
W
F
I
Q
N
GGTS
A
V
G
K
Y
A
S
Q
I
G
K
L
L
N
F
N
S
I
S
V
I
R
D
R
P
N
L
D
E
V
V
A
S
L
K
E
L
G
---------
A
T
Q
V
I
T
---
E
D
Q
-----
N
N
S
R
E
F
G
P
T
I
-
K
-
E
W
I
-
K
-------------
Q
S
G
---
G
-------
E
A
K
--
L
A
L
N
C
V
G
G
K
S
S
T
-
G
I
-----
A
R
K
L
-
N
N
--
N
----
G
L
M
L
T
Y
G
G
M
S
--
F
Q
--
P
V
T
I
P
T
S
L
Y
I
FKN
F
T
S
A
G
F
W
V
T
E
L
L
K
NN
K
E
L
K
T
S
T
L
N
Q
I
I
A
W
Y
E
E
GKLTDAKSI
E
T
L
Y
DGTKP
L
H
E
L
Y
Q
D
G
V
A
N
SKD
G
K
Q
L
I
T
Y-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
45.86
30%
-209
- C4 -
-
3SQG
-
?
D:
[165-192]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
N
D
---------
S
Y
A
K
I
F
---
S
G
D
-----
D
--
D
L
-
V
D
S
V
-
D
R
R
F
I
-
L
-------------
D
I
N
---
K
-------
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
Fugue
44.01
12%
51
* C3 *
-
2KD2
-
FAIM1_MOUSE
A:
[86-179]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPLG
S
E
N
R
S
K
T
T
S
T
W
V
L
R
L
D
G
E
---------
D
L
R
V
V
L
---
E
K
D
TM
D
V
W
C
--
N
G
Q
K
M
E
T
-
A
-
G
E
F
-
V
-------------
D
D
G
---
T
-------
E
T
H
--
F
S
V
G
N
H
D
---
C
Y
-
I
K
-----
A
V
S
S
-
G
K
--
R
KE--
G
---
I
I
H
T
L
I
V
D
N
R
-
E
I
P
E
L
T
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
Fugue
41.95
21%
-4
- C2 -
0.25
1KQ1
2
?
A:
[6-65]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
Q
D
K
A
L
E
N
F
K
A
N
Q
---------
T
E
V
T
V
F
F
LN
G
F
Q
-----
M
--
K
G
V
I
E
E
Y
-
D
-
K
Y
--------------------------------
V
--
V
S
L
N
S
Q
G
---
K
Q
-
H
L
-----
I
Y
-----------------
K
H
A
I
S
--
T
Y
-
T
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
SP3
41.28
14%
89
- C2 -
0.15
1WOQ
1
?
A:
[11-263]
---------------------------------N
A
P
L
I
G
I
D
I
G
GT
G
I
K
G
G
I
V
DLKKGKLL
G
E
R
F
R
V
P
TPQPAT
P
E
S
V
A
E
A
V
A
L
V
V
A
E
L
S
A
RPEAPAAG
S
P
V
G
V
T
F
PGIIQHGVVHSAANVDKSWLNTD
I
D
A
L
L
T
A
R
L
G
R
P
V
E
V
I
N
D
A
D
A
A
G
L
A
E
A
R
YGAGAGVK
G
T
V
L
V
I
T
L
G
T
G
I
G
S
A
F
I
F
DGKLVPNAELGHLEID
G
H
D
A
E
T
K
A
S
A
V
A
R
E
R
D
-
G
---------
L
S
W
D
E
Y
---
S
V
L
-----
L
--
Q
R
Y
F
S
H
V
-
E
-
F
L
F
---------------
S
P
E
---
L
-------------
F
I
V
G
G
G
---
I
S
-
K
R
-----
A
D
E
Y
-
L
P
NL
R
----
L
---
R
T
P
I
V
P
--
A
V
-
L
R
N
E
A
G
I
V
G
A
A
I
E
I
A
L
Q
H------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
41.06
24%
-156
- C4 -
-
1E6Y
-
MCRA_METBF
A:
[170-194]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
D
D
---------
C
Y
V
K
V
F
---
T
G
D
-----
D
--
A
L
-
A
D
E
I
-
D
K
Q
F
L
-
I
-------------
D
I
N
---
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
Fugue
40.68
17%
62
- C1 -
-
1QK9
-
MECP2_HUMAN
A:
[1-92]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
A
S
P
K
Q
R
R
S
I
I
R
D
R
G
P
M
YDDPTLPEG
W
T
R
K
L
K
---
Q
R
K
-----
S
--
G
R
S
A
G
K
Y
-
D
-
V
Y
L
-
I
-------------
N
P
Q
G
K
A
F
-------
R
S
K
--
V
E
L
I
A
Y
F
---
E
K
-
V
G
-----
D
T
S
L
-
D
P
--
N
----
D
---
F
D
F
T
V
T
--
G
R
-
G
S
G
S
-
G
C
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
40.62
25%
-275
* C5 *
-
4GFX
-
TXNIP_HUMAN
A:
[92-111]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
K
---
Y
E
-
Y
K
-----
F
G
F
E
-
L
P
--
Q
----
G
------------
P
-
L
G
T
S
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
Fugue
40.31
15%
-24
- C2 -
0.03
3F6N
-
VAP_CAMVS
A:
[3-72]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
N
Q
I
Q
K
E
V
S
E
I
L
---------
S
D
Q
K
S
M
---
K
A
D
-----
I
--
K
A
I
L
E
L
L
-
G
-
S
---
Q
-------------
N
P
I
---
K
-------
E
S
L
--
E
T
V
A
A
K
I
---
V
N
-
D
L
-----
T
K
L
I
-
N
D
--
C
----
P
---
C
N
K
E
I
L
--
E
A
-
L
G
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------