@TOME V2.3
(Mar 2018)

Ref. - - Doc.
Global output mode :
Sort entries by :
Sequence Color type :

Show alignment :
Column output:
Score:

Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : B0VPJ8: (2017-11-21 )
MWQQLITWLKQLSFLVKKEFLTIFSDPANRAILFVPALMQALLSGYAATYDVNHVDYAILDQSNGQISHELISKLDGSGIFKRVATLEYTEQIKQVTDNRQALLIIAIPNDFESKLNNNQSAPIQVIVDGRNSSTAMVAGSYLNKIIGQFNQQKFNSALPISLETRTWYNPNQESRWSLMPALIAALSMMQTLLLSALSVAREREQGTFDQLLVTPYTPLQIMIGKALPPIFVGLMQSTIILLIILFWFKIPMNGSIGLLYFGLFSFNVAVVGVGLSISALSLNMQQAMLFTFLLIMPLMLLSGLLTPVENMPKALQVATYANPLRFGINLVQRVYLEGASFAQVKLNFLPMIVLGIVTLPLAAWLFRNRLS

Atome Classification :

(20 SA) -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20......----..--30........40..---.--.....-----50.......---.60------.....-...70---...-....-..80..-----------------......90.....----...100......---------------.110..-----....-.120..-.----.---...---------130--.------...----...----------------140..-------.----------....150-...-....-----160.--.....------.170.......180-....--...190....-...200.....-...210.....-..-220-........230........240.....--..250...-......260.--......270-.-----------..----...--.-----------..---280......--.290-....-----.....-300-.-.---.-.....310....-....320.--------.......330.-------.....------.-340------------------------.--------------------------------......350....------...360........370---------------------------------------------------------------------------------------------
(Atome) (Ident) (Tito) (Num) (QMean) (Ligand) (Uniprot) -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWQQLITWLKQLSFLVKKEFLTIFSDP----AN--RAILFVPALMQALL---S--GYAAT-----YDVNHVDYA---ILD------QSNGQ-ISHE----LIS-KLDG-SGIFKR-----------------VATLEYTEQIKQV----TDNRQALLIIAI---------------PNDFES-----KLNN-NQSAPI-Q----V---IVD---------GRN--S------STA----MVA----------------GSYLN-------K----------IIGQFNQ-QKF-NSAL-----PISL--ETRTW------YNPNQESRWSLMPA-LIAA--LSMMQTLLLS-ALSVA-REREQ-GTFDQLLVTPY-TP-LQ--IMIGKALPPI-FVGLMQSTIILLIILF--WFK--IPM-NGSIGLLYFG--LFSFNVA---V-----------VG----VGL--S-----------IS---ALSLNMQQA--ML---FTFL-----LIMPL-M-L-L-S---G-LLTPVEN-MPKA-LQVATY-A--------NPLRFGINLVQ-------RVYLE------G-ASF------------------------A--------------------------------QVKLNFLPMIVLG------IVTL-PLAAWLFRNRLS---------------------------------------------------------------------------------------------
6 HHSearch 59.0318%-175 - C6 - - 5NJG ? B:[451-662] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------V-SAVEL-FVVEK-KLFIHEYISGY-YRVSS--YFLGKLLSDLLPMRMLPSIIFTCIVYF--MLG--LKPKADAFFVMMFT--LMMVAYS---A-----------SS----MAL--A-----------IA---AGQSVVSVA--TL---LMTI-----CFVFM-M-I-F-S---G-LLVNLTT-IASW-LSWLQY-F--------SIPRYGFTALQ-------HNEFL------G-QNF------------------------CPGLNATGNNPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMI------VIFL-TIAYLKLLFLKK---------------------------------------------------------------------------------------------
5 HHSearch 59.0318%-175 - C6 - - 5NJ3 ? A:[451-662] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------V-SAVEL-FVVEK-KLFIHEYISGY-YRVSS--YFLGKLLSDLLPMRMLPSIIFTCIVYF--MLG--LKPKADAFFVMMFT--LMMVAYS---A-----------SS----MAL--A-----------IA---AGQSVVSVA--TL---LMTI-----CFVFM-M-I-F-S---G-LLVNLTT-IASW-LSWLQY-F--------SIPRYGFTALQ-------HNEFL------G-QNF------------------------CPGLNATGNNPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMI------VIFL-TIAYLKLLFLKK---------------------------------------------------------------------------------------------
26 Fugue 57.7515% -78 * C6 * - 5DO7 - ABCG5_HUMAN A:[34-650] EPHSLGILHASYSRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGEVYVNGRALRREQFQDCFSYVLQSDTLLSSLTVRETLHYTALLAIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNYSLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGT----------------PAEMLDFF---NDCGYPCP-----EHSNPFDFY---MDLTSVDTQSKERE-IETS----KRV-QMIE-SAYKKS-----------------AICHKTLKNIERM----KHLKTLPMVPFK---------------TKDSPG-----VFSK-LGVLLR-R----V---TRN---------LVR--N------KLA----VIT----------------RLLQN-------L----------IMGLFLL-FFV-LRV-------------RSNV------LKGAIQDRVGLLYQ-FVGA--TP--YTGMLN-AVNLF-PVLRA-VSDQESQDGLY-QK-WQ--MMLAYALH-V-LPFSVVATMIFSSVCY--WTL--GLH-PEVARFGYFS--AALLAPH---L-----------IG----EFL--T-----------LV---LLGIVQNPN--IVNSVVALL-----SIAGV-L-V-G-S---G-FLRNIQE-MPIP-FKIISY-F--------TFQKYCSEILV-------VNEFY------G----------------------------------------------------------------LNFTCAFTQG------IQFI-EKTCPGATSRFTMNFLILYSFIPALVILGIVVFKIRDHLIS----------------------------------------------------------------
21 Fugue 53.7918% -32 - C5 - - 4TXD - ? A:[21-369] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KRDVLAELGLGDLRPYLRSIGDKDRIFPK--AHRIEVVFLVRAAN---Y--LLLRT-----EGAGTINMT---TLE------YSGGA-MEVP----VIQ-PQKL-MAVTRR-----------------QMLQLLREYRDSL----DEVSKRWLVQEV---------------IGKAKD-----LGFK-KVSEEW-N----C---TIQ---------GMDGFC------PHC----TIF----------------GAALT-------E--------------QHN-EKF-GG-L-----SIGI--KTRVR------FDPAFATQRRITPE-T--------HNKVTEG-HLSM----TGQ-ALFSEVHVEPG-T------VFIGRAEL----VDLTEPELVATLYSL--ATL--REL-GGRSG--IYG--TVRVEIL---G-----------VK----AGKYAS-----------TT---AYDLAAENAGKGY---EEVK-----KNLKE-R-L-E-K---L-GFTPV-D-NSKL-LAAVDH-K--------DPN----GLFK-------DLWRS------S-IDF------------------------A--------------------------------EKMVKWVEELKGG------G-------------------------------------------------------------------------------------------------------------
24 Fugue 52.0722% -39 - C3 - - 5IH3 CARM1_MOUSE A:[10-352] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVFSERTEESSAVQYFQFYGYLSQQQNMM---QD----YV--RTGTYQRAILQ----------------------NHTDFKDKIVLD------VGCGSGILSF----FAA-QAGA-RKIYAV-----------------EASTMAQHAEVLV----KSNNLTDRIVVI---------------PGKVEEVSLPEQVDI-IISEPMGY----M---LFN---------ERM--L------ESY----LHA----------------KKYLK-------P----------SGNMFPT-IGD-VHLA-----PFT---DEQLY------MEQFTKANFWYQPS----------FHGVDLS-ALRGA-AVDEY---FRQPVVDTF-D--IR--ILMAKSVKYT-VNFLEAKEGDLHRIEI--PFK--FHM-LHS-GLVHGL--AFWFDVA---F-----------IGSIMTVWL--S-----------TAPTEPLTHWYQVR--CL---FQSP-----LFAKA-GDT-L-S---G-TCLLIAN-KRQS-YDISIV-A--------QVDQTGSKSSN-------LLDLK------N-PFF------------------------------------------------------------------------------------------RYT---------------------------------------------------------------------------------------------
2 PsiBlast_PDB 51.6822%-174 - C6 - - 5NJG - ? A:[480-600] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LGKLLSDL-LPMRMLPSIIFTCIVY--FMLGLKPK-ADAFFVMMFT--LMMVAYS---A-----------SS----MAL--A-----------IA---AGQSVVSVA--TL---LMTI-----CFVFM-M-I-F-S---G-LLVNLTT-IASW-LSWLQY-F--------SIPRYGFTALQ-------HNEFL------G-QNF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1 PsiBlast_PDB 51.6822%-174 - C6 - - 5NJ3 - ? A:[480-600] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LGKLLSDL-LPMRMLPSIIFTCIVY--FMLGLKPK-ADAFFVMMFT--LMMVAYS---A-----------SS----MAL--A-----------IA---AGQSVVSVA--TL---LMTI-----CFVFM-M-I-F-S---G-LLVNLTT-IASW-LSWLQY-F--------SIPRYGFTALQ-------HNEFL------G-QNF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9 HHSearch 51.6413%-157 - C6 - - 5DO7 - ABCG8_HUMAN B:[472-668] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-CYSER-AMLYYELEDGLYTT-GP--YFFAKILGEL-PEHCAYIIIYGMPTYW--LAN--LRPGLQPFLLHFLL--VWLVVFC---C-----------RI----MAL--A-----------AA---ALLPTFHMA--SF---FSNA-----LYNSF-Y-L-A-G---G-FMINLSS-LWTV-PAWISK-V--------SFLRWCFEGLM-------KIQFS------R-RTYKMPLGNLTIAVSGDKILSVMELDSY--------------------------------PLYAIYLIVIGLS------GGFM-VLYYVSLRFIK----------------------------------------------------------------------------------------------
10 HHSearch 50.0213%-160 - C6 - - 5DO7 - ABCG8_HUMAN D:[472-668] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-CYSER-AMLYYELEDGLYTT-GP--YFFAKILGEL-PEHCAYIIIYGMPTYW--LAN--LRPGLQPFLLHFLL--VWLVVFC---C-----------RI----MAL--A-----------AA---ALLPTFHMA--SF---FSNA-----LYNSF-Y-L-A-G---G-FMINLSS-LWTV-PAWISK-V--------SFLRWCFEGLM-------KIQFS------R-RTYKMPLGNLTIAVSGDKILSVMELDSY--------------------------------PLYAIYLIVIGLS------GGFM-VLYYVSLRFIK----------------------------------------------------------------------------------------------
23 Fugue 49.9616% -21 - C4 - - 3J9O - ? B:[79-505] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VIDKLIDLQVNSIISNDEFRALEQEWLKVQE-VCQEDYDNVEVSI----LD--VKKEELQYDFERNL---Y--DISSS-----DFFKKVYVS---EFD------QYGGE-PYGA----ILG-LYNF-E---NT-----------------TNDIIWLTGMGMV----AKNSHAPFIASIDKSFFGVKDLSEITHIKSFEA-----LLEH-PRYKEW-N----D---F------------RN--L------DVAAYIGLTV----------------GDFML-------R----------QPYNPEN-NPV-QYKL-----MEGF--NEFVD------YDKNESYLWGPASI-HLVK--NMMRSYDKTR-WFQYI-RGVES-GGYVKNLVACV-YD-NKGILETKSPLNVL-FADYMELSLANIGLIP--F----VSE-KGTSNACFFS--VNSAKKVEEFV-----------DG----FDS--A-----------NS---RLIANLSYT--MC---ISRI-----SHYIK-C-V-I-RDKIG-SIVDVES-IQKI-LSDWIS-EFVTTVYQPTPLEMARYPFR-------NVSIEVKTIPGK-PGW------------------------Y--------------------------------SCKINVIPHIQFEGMNTTMTIDT-RLEPELFGTNN----------------------------------------------------------------------------------------------
8 HHSearch 49.7316%-140 - C6 - - 5DO7 - ABCG5_HUMAN C:[440-647] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLF-PVLRA-VSDQESQDGLY-QK-WQ--MMLAYALHVL-PFSVVATMIFSSVCYW--TLG--LHPEVARFGYFSAA--LLAPHLI---G-----------EF----LTL--V-----------LL---GIVQNPNIV--NS---VVAL-----LSIAG-V-L-VGS---G-FLRNIQE-MPIP-FKIISY-F--------TFQKYCSEILV-------VNEFY------G-LNF------------------------TCGSMCAFTQGIQFIEKTCPGATS---------RFTMNFLILYSFI------PALV-ILGIVVFKIRDH---------------------------------------------------------------------------------------------
7 HHSearch 45.4816%-135 - C6 - - 5DO7 - ABCG5_HUMAN A:[440-647] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLF-PVLRA-VSDQESQDGLY-QK-WQ--MMLAYALHVL-PFSVVATMIFSSVCYW--TLG--LHPEVARFGYFSAA--LLAPHLI---G-----------EF----LTL--V-----------LL---GIVQNPNIV--NS---VVAL-----LSIAG-V-L-VGS---G-FLRNIQE-MPIP-FKIISY-F--------TFQKYCSEILV-------VNEFY------G-LNF------------------------TCAFTQGIQFIEKTCPGATS-------------RFTMNFLILYSFI------PALV-ILGIVVFKIRDH---------------------------------------------------------------------------------------------
25 Fugue 45.0619% -47 - C2 - - 5L35 - ? A:[1-422] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PNNLDSNVSQIVLKKFLPGFMSD----LV--LAKTVDRQLLAGEINSST--GDSVS-----FKRPH-QFS---SLR------TPTGD-ISGQNKNNLISGKATG-RVGNYI-----------------TVAVEYQQLEEAI----KLNQLEEILAPV---------------RQRIVT-----DLET-ELAHFM-M----NNGALSL---------GSP--NTPITKWSDV----AQT----------------ASFLK-------DLGVNEGENYAVMDPWSA-QRL-ADAQTGLHASDQL--VRTAW------ENAQIPTNFGGIRA-LMSNGLASRTQGAFGG-TLTV----KTQ-PTVTYNAVKDS-YQ-FT--VTLTGATASV-TGFLKAGDQVKFTNTY--WLQ--QQT-KQA---LYNGATPISFTAT---VTADANSDSGGDVT----VTL--SGVPIYDTTNPQYN---SVSRQVEAG--DA---VSVVGTASQTMKPN-L-F-Y-N---K-FFCGLGS-IPLPKLHSIDS-A--------VATYEGFSIRV-------HKYAD------GDANV------------------------Q--------------------------------KMRFDLLPAYVC--------FNP-HMGGQFFGNP-----------------------------------------------------------------------------------------------
19 HHSearch 42.6629%-163 - C6 - - 2MWT - A:[6-29] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FFKKVKKSVKKRLKKIFKKP----MV--IG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4 HHSearch 41.8811%-112 - C6 - - 5XJY ? A:[533-1116] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PIATEVWLINKSMELLDERKFWAGIVF---------------TGITPG-----SIEL-PHHVKY-K----I---RMD---------IDN--V------ERT----NKIKDGYWDPGPRADPFEDMRYVWGGFAYLQD----------VVEQAII-RVLTGTEK-----KTGV--YMQQMPYPCYVDDIFLRVMSRSMPL-FMTL--AWIYS-VAVI-IKGIV-YEKEA-RLKETMRIMGL-DN-SI--LWFSWFISS--LIPLLVSAGLLVVILK--LGN--LLP-YSDPSVVFVF--LSVFAVV---T-----------IL----QCF--L-----------IS---TLFSRANLA--AA---CGGI-----IYFTL-Y-L-P-Y---VLCVAWQDY-VGFT-LKIFASLL--------SPVAFGFGCEYFALFEEQ---------------------------------------------------------------------------GFNLTTSVSMM------LFDT-FLYGVMTWYIE----------------------------------------------------------------------------------------------
12 HHSearch 41.1819%-101 - C5 - - 3CNI - ? A:[11-87] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QKVA---IVR------EDTGT-IAEL----AEK-ALG---NMVDI-----------------VYAGSDLKEAEEA----VKKEKAPAIIVI---------------PKGFSQ-----SLES-GEKARL-E----IVW-YLR---------GT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28 Fugue 40.2316% -20 - C4 - - 2O1S DXS_ECOLI A:[3-620] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVSRS----SGHFASGLGTVELTVALH---Y--VYNTPFDQLIWDVGHQAYP---HKI------LTGRR-DKIG----TIR-QKGGLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKE----GKNRRTVCVIGD---------------GAITAGM----AFEAMNHAGDI-RPDMLV---ILN---------DNE--P------GTL----FEELGFNYIGPVD------GHDVL-------G----------LITTLKNMRDL-KGPQ-----FLHIMTKKGRG------YEPALPSYSKIFGD-WLCE--TAAKDNKL--MAITPAMREGSGMVEFSRKFPDRY-FD-VA--IAEQHAVT-F-AAGLAIGGYKPIVAIYSTFLQ--RAY-DQVLHDVAIQ--KLPVLFA---I-----------DR----AGI--------------VG---ADGQTHQGA--FD---LSYL-----RCIPEMV-IMT-P---S-DENECRQMLYTG-YHYNDG-P--------SAVRYPRGNAV-------GVELT------P-LEKLPIGK-------------------G--------------------------------IVKRRGEKLAILN------FGTLMPEAAKVAESLNATLVDMRFVKPLDEALILEMAASHEALVTVEENAIMGGAGSGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEMRAELGLDAAGMEAKIKAWLA
22 Fugue 29.3814% -78 - C5 - - 2MQ8 - ? A:[1-112] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLTVEVEVKITADD----EN--KAEEIVKRVIDEVE---R--EVQKQ-----YP-NATITR---TLT------RDDGT-VELR----IKV-KADT-EEKAKS-----------------IIKLIEERIEEELR---KRDPNATITRTV---------------RTEVGS-----SWSL-EHHHHH-H----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20 Fugue 28.6614% 10 * C5 * - 3CNI - ? A:[11-155] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QKVA---IVR------EDTGT-IAEL----AEK-ALGNMV---DI-----------------VYAGSDLKEAEEA----VKKEKAPAIIVI---------------PKGFSQ-----SLES-GEKARL-E----I---VWYLRGTGLSEAVST--G------TIS----SLI----------------ESLKV-------Q----------LASFLLN-DPK-KAQLLFD--PLEI--VQHTY------LRGSLFKNHSPEAIMNVFY--SQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18 HHSearch 26.3916%-102 - C6 - - 5DO7 - ABCG8_HUMAN D:[395-437] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PGAVQQFTTLIRRQISNDFRDL----PT--LLIHGAEACLMSMT---I--GFLY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------