@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VTK0: (2017-12-14 )
MNAPVKTENHLSVQQESPIDKTLSMIERIALDPSSDVAKLEKMIELQERVMKTQAKQAYDNAMVLAQSEMPPIDKFKKGHNSNYAPLDHIMSIVFPVLKRNNLFVRWTSDPKENGSLCVTCICSHVGGHSETSSMDVKEDRGGSKSDIQGMGSAFTYAKRYTLSALLGLVLTDDTDGARINLKVTDAQATMLRNKLKFFKPEALEAFKAKIGCEVEELPRGDFDYWCSYIDNQINKLMANQGEKNANP
Atome Classification :
(20 SA)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20........30........40.......--.50.-.......60.......------------.70.-.......80.......--.90........-100-.......110.......120.......130.....--..140.......150.......------160-........170..-......180.--------------------------------......190.-......------200.....------------...210.......220-.......230..---.......240......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNAPVKTENHLSVQQESP
I
D
K
T
L
S
M
I
E
R
IALDPS
S
D
V
A
K
L
E
K
M
I
E
L
Q
E
--
R
V
M
K
-
T
Q
A
K
Q
AYD
N
A
M
V
L
AQS------------EMP
P
-
I
D
K
F
KKGHNSNYA
P
L
D
--
H
I
M
S
I
V
F
P
V
LK-RN
N
-
L
F
V
R
WTSDPKENG
S
L
C
V
T
C
I
C
S
HVGGHSETSSMDV--KEDRGGSK
S
D
I
Q
G
M
G
S
A
F
T
Y
A
K
------
R
Y
--
T
L
S
A
L
L
G
L
V
-LTD-DTDG
A
R
I
N
L
K
--------------------------------
V
TD
A
Q
A
T
M
L
R
-
N
K
L
K
FF------
K
-
P
E
A
L
E
A
------------
F
K
A
K
IGC
E
V
E
ELPRG
D
-
F
D
Y
W
C
S
Y
I
--
D
N
---
Q
I
N
K
L
M
ANQGEKNANP
23
Fugue
74.23
14%
-
- C5 -
-
4N74
-
?
A:
[264-577]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TQ
N
T
I
E
T
G
V
G
Y
S
TDV
G
P
R
V
K
A
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W
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K
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M
P
L
L
K
N
P
L
E
Q
Y
Y
L
V
Q
G
G
F
--
K
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D
-
L
N
D
T
E
S
D
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A
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D
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SSG
W
Q
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A
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N
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-
V
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E
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T
T
M
L
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--
Y
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R
S
-
R
G
G
-
L
M
P
T
W
--------------------
G
D
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Q
R
Y
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I
D
Y
--
S
N
T
A
W
G
S
D
V
D
F
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A
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N
V
W
I
R
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YDR
H
R
F
--
V
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I
-
E
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D
K
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D
RSIRGYKYKS
I
A
P
K
Y
ANG
D
L
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A
S
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I
T
G
S
L
E
Y
Q
Y
N
-
V
T
G
K
W
W
------
G
-
A
V
F
V
D
S
G
E
A
V
SDIRRSD
F
K
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G
T
G
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G
V
R
W
E
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P
V
G
P
-
I
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A
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V
A
D
K
---
D
E
H
G
L
Q
F
Y
I
G
L
G
P
E
L
-
22
Fugue
64.29
21%
-15
- C2 -
-
4D0L
2
PI4KB_HUMAN
A:
[10-566]
S
W
L
L
R
L
F
E
SKLFD
I
S
M
A
I
S
Y
L
Y
N
SKE
P
G
V
Q
A
Y
I
G
N
R
L
FCFR
N
E
D
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D
F
Y
L
P
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L
N
M
Y
I
HMD
E
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A
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Y
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R
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N
F
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A
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L
L
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A
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SR
G
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R
K
L
I
L
SRL
A
P
E
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E
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L
M
A
I
G
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R
L
ATLPT
K
E
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K
T
Q
R
L
I
S
E
L
S
L
L
N
H
K
LPARVWLPTAG
F
D
H
H
V
V
RVPHTQAVVLNSKDK
A
P
Y
L
I
Y
V
E
V
L
E
C
ENFDTTSV
P
A
R
I
PENPSAVALKEP
W
Q
E
K
V
R
R
I
R
E
G
SPYGHLPN
W
R
L
L
S
V
I
V
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CGDDL
R
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E
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L
A
F
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K
Q
L
Q
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I
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E
Q
E
RVP
L
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ISAD
S
G
M
I
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P
V
V
N
A
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V
K
K
Q
S
----
Q
L
S
L
L
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Y
F
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E
H
G
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Y
--
T
T
E
A
F
L
S
A
Q
R
--
N
F
V
Q
-
S
C
A
--
G
Y
C
L
V
C
Y
L
L
Q
---------------------
V
K
D
R
H
N
G
N
I
L
L
D
A
EG
H
I
I
H
I
D
F
G
F
I
L
-
S
S
S
-
S
A
F
K
L
T
-----------
T
E
F
V
D
V
M
G
G
L
D
-----------------------
G
D
M
F
N
Y
Y
K
------
M
L
--
M
L
Q
G
L
I
A
A
R
----------
K
H
M
D
K
--------------------------------
V
V
Q
I
V
E
I
M
Q
Q
G
S
Q
L
P
C
F
------
H
G
S
S
T
I
R
N
------------
L
K
E
R
F
H
M
---------------
S
M
T
--
E
E
---
Q
L
Q
L
L
V
E
Q
M
V
D
G
S
M
R
S
24
Fugue
58.84
12%
-43
- C1 -
-
2P4F
1
?
A:
[95-299]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
D
K
P
Y
K
T
L
D
D
Y
L
K
L
D
K
I
K
D
L
S
K
--
Q
E
V
E
-
F
L
W
R
A
K
W
S
N
R
D
D
S
L
V
A
------------
V
V
P
Y
-
V
K
T
F
Q
G
M
Y
K
Y
A
V
K
------
N
P
L
F
V
L
P
L
P
R
P
V
E
L
-
Q
Y
V
Q
W
Q
F
A
G
P
N
T
V
H
C
L
I
T
S
L
A
E
Y
---------------
K
L
H
Q
D
F
A
K
P
H
T
T
I
Q
F
H
L
D
L
A
N
------
D
K
--
D
M
V
L
M
N
G
Q
V
-
E
S
D
-
S
--------
N
--------------------------------
V
S
L
Q
D
A
Q
L
L
L
-
L
N
V
Q
R
F
Y
GAMGS
E
-
T
S
I
A
K
E
------------
R
I
Q
L
L
E
D
F
N
K
G
S
Q
N
F
D
-
I
N
K
L
I
Q
L
A
--
Q
S
---
M
E
N
-------------
27
Fugue
51.56
10%
-81
- C5 -
-
1QST
1
?
A:
[1-160]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
F
D
I
L
T
N
----
D
-------------
G
T
H
R
N
M
K
L
L
I
D
L
K
N
I
F
S
--
R
Q
L
---
P
----------------------------
K
M
-
P
K
E
Y
I
V
K
L
V
F
---
D
R
H
--
H
E
S
M
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I
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K
N
K
Q
-
K
V
I
-
G
G
I
C
F
R
Q
Y
K
--------------
P
Q
R
F
A
E
V
A
F
L
A
V
--
T
A
N
E
Q
V
R
G
Y
G
T
R
L
M
N
K
F
K
D
H
M
Q
------
K
Q
---
N
I
E
Y
L
L
T
Y
-
A
D
N
---------------------------------------------------------------------
F
A
I
G
Y
------------
F
K
K
-
Q
G
F
T
K
--
E
H
R
M
P
-
Q
E
K
W
K
G
Y
I
--
K
D
Y
DG
G
T
L
M
E
C
Y
I
H
P
Y
V
D
Y
--
25
Fugue
50.70
11%
-21
- C4 -
-
1YAR
-
?
O:
[10-237]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
R
A
A
L
I
Q
N
L
R
D
S
Y
T
E
T
S
S
F
A
V
I
E
E
W
A
A
G
T
L
Q
E
I
E
G
I
A
K
A
A
A
E
A
H
--
G
V
I
R
-
N
S
-
T
Y
G
R
A
Q
A
E
K
S
P
E
Q
------------
L
L
G
V
-
L
Q
R
Y
Q
D
L
C
H
N
V
Y
C
Q
A
E
--
T
I
R
T
V
I
A
I
R
I
P
-
E
H
K
---------
E
E
D
N
L
G
V
A
V
Q
H
A
V
L
K
I
I
D
E
L
E
I
K
T
L
G
S
GE
K
S
G
S
G
G
A
P
T
P
I
G
M
Y
A
L
R
E
Y
L
S
A
------
R
S
--
T
V
E
D
K
L
L
G
G
--
G
S
-
Q
S
P
S
L
L
L
E
L
R
--------------------------------
Q
I
D
A
D
F
M
L
K
V
-
E
L
A
T
T
H
------
L
-
S
T
M
V
R
A
------------
V
I
N
A
Y
L
L
N
W
K
K
L
I
Q
------------------------
P
R
T
G
S
D
H
M
V
S
26
Fugue
50.55
21%
73
* C5 *
-
5JEN
-
LYSC_CHICK (first)
A:
[62-271]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
V
K
A
I
T
F
I
E
I
K
E
E
K
--------------
D
Q
S
S
I
D
V
K
T
P
A
L
S
G
L
S
N
--
K
E
L
E
-
N
S
I
N
E
K
Y
L
K
E
S
Q
Q
L
Y
K
------------
E
F
I
Q
S
T
S
K
N
K
K
G
H
L
S
I
Y
S
D
Y
E
--
T
V
T
D
T
P
D
L
L
S
I
-
R
R
N
-
I
E
T
T
Q
A
S
--------------------
S
Y
T
Q
S
R
Y
I
--
T
I
D
K
---
K
N
D
I
L
L
T
L
K
S
L
F
K
D
E
------
R
Y
I
K
V
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Q
N
I
K
E
Q
M
K
Q
Q
M
K
E
D
P
N
K
I
-
Y
W
--------------------------------
L
T
D
E
D
A
E
P
F
K
-
T
I
L
P
D
Q
------
T
-
F
Y
I
T
E
D
------------
H
K
L
V
I
S
F
D
E
Y
E
V
A
P
G
Y
M
G
V
T
E
F
T
I
P
--
T
G
---
V
I
S
N
L
L
V
G
E
R
Y
I
R
---
6
PsiBlast_PDB
45.63
39%
-113
- C6 -
-
3WP1
-
B:
[129-156]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
N
V
L
E
I
N
K
--
R
I
T
E
-
E
Q
A
R
K
A
F
D
R
A
T
K
L
E
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
45.40
39%
-122
- C6 -
-
5B64
-
A:
[131-158]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
N
V
L
E
I
N
K
--
R
I
T
E
-
E
Q
A
R
K
A
F
D
R
A
T
K
L
E
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
45.40
39%
-126
- C6 -
-
1JXM
-
A:
[232-259]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
N
V
L
E
I
N
K
--
R
I
T
E
-
E
Q
A
R
K
A
F
D
R
A
T
K
L
E
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
44.99
39%
-105
- C6 -
-
1KJW
-
A:
[226-253]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
N
V
L
E
I
N
K
--
R
I
T
E
-
E
Q
A
R
K
A
F
D
R
A
T
K
L
E
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
43.16
39%
-111
- C6 -
-
3WP0
1
A:
[129-156]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
N
V
L
E
I
N
K
--
R
I
T
E
-
E
Q
A
R
K
A
F
D
R
A
T
K
L
E
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
42.37
8%
-190
- C6 -
-
1TH5
-
NIFU1_ORYSJ
A:
[158-182]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
N
V
E
--
K
V
L
N
E
I
R
P
Y
L
A
-
G
T
G
G
G
G
L
Q
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
42.31
39%
-120
- C6 -
-
1JXO
-
DLG4_RAT
A:
[655-682]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
N
V
L
E
I
N
K
--
R
I
T
E
-
E
Q
A
R
K
A
F
D
R
A
T
K
L
E
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
40.41
16%
-92
- C6 -
-
1V8D
-
Y214_THET2 (first)
A:
[77-154]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
T
R
P
S
L
E
A
A
H
--
A
V
L
E
G
L
L
P
P
L
L
-
E
R
G
-
V
H
V
A
V
Q
A
C
E
H
L
N
R
A
L
V
V
E
R
E
T
A
R
A
F
G
K
E
E
V
A
V
F
P
H
------------
P
K
A
G
G
A
K
A
T
A
A
F
------
L
R
--
F
--------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
30.52
20%
70
- C6 -
-
4OD8
-
A20_VACCC
C:
[3-52]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
S
S
A
D
L
T
N
L
K
E
L
L
S
L
Y
K
S
L
R
F
S
D
-
S
A
A
I
E
K
Y
N
S
L
V
E
W
G
T
S
------------
T
Y
W
K
-
I
G
V
Q
K
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
28.30
17%
-119
- C6 -
-
2LSE
-
?
A:
[50-85]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
E
K
F
R
D
------------
E
M
E
Q
-
M
Y
K
D
A
P
N
-----
A
V
M
E
--
Q
L
L
E
E
I
E
K
L
L
K
-
K
A
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
27.93
12%
141
* C6 *
-
2YMY
-
RASF5_MOUSE
A:
[2-41]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
P
E
L
Q
N
F
L
T
I
L
E
K
E
E
--
Q
D
K
I
-
H
Q
L
Q
K
K
Y
N
K
F
R
Q
K
L
E
E
------------
A
L
R
E
-
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
27.49
11%
8
- C6 -
-
2AZE
-
E2F1_HUMAN
B:
[215-252]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
S
E
Q
Q
L
D
H
L
M
N
I
C
T
T
------------
Q
L
R
L
-
L
S
E
D
T
D
S
Q
R
L
A
Y
V
T
C
Q
--
D
L
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
27.25
21%
85
- C6 -
-
5TUU
-
B:
[8-60]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
L
I
E
L
K
A
--
E
I
E
E
L
Q
Q
R
E
Q
E
L
D
Q
H
K
V
W
V
Q
Q
------------
S
I
R
N
-
V
T
E
D
V
Q
N
S
C
L
A
Y
V
T
H
E
--
D
I
C
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
25.95
8%
80
- C6 -
-
3T97
-
NUP54_RAT
B:
[345-402]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
M
T
K
Q
H
Q
T
R
L
D
I
I
S
E
D
I
S
E
L
Q
K
N
Q
T
T
T
M
A
K
I
A
Q
Y
K
R
K
L
M
D
L
S
H
--
R
T
L
Q
-
V
L
I
K
Q
E
I
Q
R
K
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------