@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VTQ4: (2017-12-14 )
MNKPLSSRFLFKSFGMVAVCMSLAACGDKAWWSNNDEPELESQQIKRLIPSRVHDRESWAKDIDDIMKDLDIPKTKQNVCSIVAVVDQESNFVANPQVPGLGQKAVEEVSTRLNEKFEDKLGKTIGGTIAGYFEEVLRTQPSPDNNYMSQMRKVKTEKDLDLLYREIFDFMAKHYHVSALTGAAKLVGQDIGEKMNPITTLGSMQVHINYAKANKRSSMNTAALRDDLYTEYGGLYYGIHRLMVYPADYDKAIYRFADYNSGMYSSRNAAFQKMLKELTDKDISLDGDLLLYTKDGDPRATQSESEKELITVFASNNVLVTPRQIRDDLKLEKEKKFESTQTYIALTKLYKSKTGKEPLYAIMPQVVISGPKLSRDYNTNWYATRVNGRYETCMQRAKRIRL
Atome Classification :
(20 SA)
-------------------------------------------------.........10........20---.......----------..30---........40.-------------..----.-----....50-........60......--..--70.-----....-.-..80........90..-.----.....100......--------------------.-110---.........120.......-------130..-------.....140......--.150.....--..160......---.170......---------------.---------------180---------------------------------.........190.......200..-----.....210.-....----..------------------220...-...-------------------.230--..---.....240..------------......250-.----.....---.260.....-..270......--------.280...-------....--290.......300....--...310----........320-------.......330---.......340.---------...----...----------350.--......360...-----...----.370....-----....380.......----390---........400-------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-------------------------------------------------MNKPL
S
S
R
F
L
F
K
SF
G
M
V
A
V
C
----
M
S
L
A
ACG----------DKAW---WSNNDEPE
L
E
S
-------------
Q
Q
----
I
-----
K
R
L
I
P
S
-RVH
D
R
E
S
W
A
K
D
I
D
D
I
M
--
K
D--LDI-----PK
T
K
-
Q
-
N
V
C
S
I
V
A
V
VDQESNFV-A----NPQVPGL
G
Q
K
A
V
E
E
--------------------
V
-
S
-----
T
R
L
N
E
K
F
E
D
K
L
G
K
TI
G
G
T
I
-------
A
G
Y
F
E
-------
E
V
L
RTQPSP
D
N
N
Y
M
--
S
Q
M
R
KVKTE--K
D
L
D
L
L
Y
R
E
I
F
---
D
F
M
A
K
H
Y
H
V
S
---------------
A
---------------
L
-----------------------------------
T
G
A
A
K
L
V
G
Q
D
I
G
EKMNP
I
T
TLG
S
M
-----
Q
V
H
I
N
Y
AKA-NKRS----SM------------------
N
T
A
A
L
R
-
D
D
L
-------------------
Y
T
E
Y--
G
G
---
L
Y
Y
G
I
H
R
-
L
M
------------VYPA
D
Y
D
K
A
-
I
----
Y
R
FAD---YNSGMYSS
R
-
N
A
A
F
Q
K
M
L
K
E
L
--------TDKDISL-------DG
D
L
--
L
L
Y
TKDGDPRATQSESE--K
E
L
I
T
-----
V
F
ASN
N
V
L
V
T
P
-------
R
Q
I
R
D
D
L
K
L
E
---
K
E
KKFES
T
Q
T
Y
---------
I
A
L
----
T
K
L
----------
Y
KSK--TGKE
P
L
Y
A
I
M
P
Q
-----
V
VI----SG-PKLSR-----DYNT
N
W
Y
A
T
RVN
G
R
----
Y
E
----
T
C
M
Q
R
A
K
RIRL-------------------------------------------------------------------------------------------------------
39
Fugue
62.77
16%
-55
- C1 -
-
4E8Y
2
?
A:
[43-350]
------------------------------------------------------
V
V
P
V
P
R
E
Q
L
A
R
S
R
V
L
----
V
V
G
D
V
M
L
----------
D
R
Y
W
---
F
G
N
V
D
R
I
S
P
E
A
-------------
P
-----
V
-----
P
V
V
H
V
Q
-
R
Q
E
E
R
L
G
G
A
A
N
V
A
R
N
A
--
V
T
--
L
------------------------------------
G
G
Q
A
G
L
L
C
V
V
G
C
D
E
--------------------
P
-
G
-----
E
R
I
V
E
L
L
G
S
S
G
V
T
P
H
L
E
R
D
-------
P
A
L
P
T
-------
T
I
K
L
R
V
L
A
R
Q
Q
Q
L
L
--
R
V
D
F
E
A
M
P
T
--
H
E
V
L
L
A
G
L
A
R
F
---
D
V
L
L
P
Q
H
D
V
V
---------------
L
---------------
M
-----------------------------------
S
D
Y
A
K
-------------
G
G
L
T
H
V
-----
T
T
M
I
E
K
A
R
A
-
A
G
K
-----------------------------------------------------------------------
A
-
V
L
------------
V
D
P
K
G
D
D
W
A
-
R
----
Y
R
G
A
S
-------
L
I
T
P
N
-
R
A
E
L
R
E
V
V
G
Q
W
--------
K
S
E
D
-
D
L
-------
R
A
R
V
--
A
N
L
R
A
E
L
D
I
D
A
L
L
L
T
R
S
--
E
E
G
M
T
-----
L
F
S
A
G
G
E
L
H
A
P
-------
A
L
A
R
E
-------------------------------------
V
----------
F
D
V
S
--
G
A
G
D
T
V
I
A
T
V
A
T
-----
M
L
G
----
A
G
V
P
L
V
D
A
-----
V
V
L
A
N
R
A
A
G
I
V
V
G
K
----
L
G
----
T
--
A
T
V
D
Y
D
E
L
-------------------------------------------------------------------------------------------------------
41
Fugue
62.43
16%
-28
- C4 -
-
3LD1
-
R1A_IBVM
A:
[5-363]
-----------------------------------------------------------
L
R
D
V
I
L
V
S
K
D
----
I
P
-
E
Q
L
C
----------
D
A
L
F
---
F
Y
T
S
H
N
P
------------------------------
K
D
Y
A
D
-
A
F
A
V
R
Q
K
F
D
R
N
L
Q
T
----
G
K
--
Q
F
K
-----
F
E
T
V
-
C
-
G
L
F
L
L
K
G
V
--------------
D
K
I
T
P
G
V
P
A
K
V
L
K
A
--------------------
T
-
S
-----
K
--
L
A
D
L
E
D
I
F
G
V
S
---
P
F
-------
A
R
K
Y
R
-------
E
L
L
K
T
A
C
Q
W
S
L
T
V
E
--
T
L
D
A
R
A
L
T
L
--
D
E
I
F
D
P
T
E
I
L
W
---
L
Q
V
A
A
K
I
Q
V
S
---------------
A
---------------
M
A
M
R
R
L
V
-----------------------------
G
E
V
T
A
K
V
M
D
A
L
G
S
N
M
S
A
L
F
Q
I
F
K
Q
-----
Q
I
V
R
I
F
Q
A
A
L
A
I
F
E
----
N
V
------------------
S
E
L
P
Q
R
I
A
A
L
-------------------
K
M
A
F
--
A
K
---
C
A
K
S
I
T
V
-
V
V
------------
M
------
E
R
-
T
----
L
V
V
R
E
---
F
A
G
T
C
L
A
S
I
-
N
G
A
V
A
K
F
F
E
E
L
P
N
G
F
MG
A
K
I
F
T
T
F
A
F
-------
F
R
E
A
--
A
V
K
I
V
D
N
I
P
N
A
P
R
G
T
----
K
G
F
E
V
-----
V
G
N
A
K
G
T
Q
V
V
V
-------
R
G
M
R
N
D
L
T
L
L
---
D
Q
K
A
E
I
P
V
E
S
------------------
E
G
----------
W
S
A
I
--
L
G
G
H
L
C
Y
V
F
K
S
----------------------------
G
D
R
F
Y
A
A
P
L
S
G
N
----
F
A
LHD
V
H
C
C
E
R
V
V
C
L
---------------------------------------------------------------------------------------------------------
43
Fugue
61.16
17%
48
- C6 -
-
4PG7
4
?
A:
[20-446]
-------------------------------------------------
H
M
K
K
L
N
I
A
L
L
--
G
L
G
T
V
G
S
G
----
V
V
K
I
I
E
E
----------
N
R
Q
Q
---
I
Q
D
T
L
N
K
D
I
V
I
-------------
K
H
----
I
L
V
RDK
S
K
K
R
P
L
-
N
I
S
Q
Y
H
L
T
E
-
D
V
N
E
I
L
--
N
D
DS
L
D
I
I
V
E
VM
G
G
I
E
-
P
-
T
V
D
W
L
R
T
A
L
K
N
K
K
H
V
I
T
A
----
N
K
D
L
L
A
V
H
L
K
L
L
E
D
--------------------
L
-
A
-----
E
E
N
G
V
A
L
K
F
E
A
S
V
A
G
G
P
N
N
-------
I
S
K
F
M
-------
G
I
L
---
N
G
T
S
N
F
I
L
--
S
K
M
T
K
E
Q
T
T
--------
F
E
E
A
L
---
D
E
A
K
R
L
G
F
A
E
---------------
A
---------------------------------------------------
D
P
T
D
D
V
E
G
V
D
A
A
R
K
V
V
-
I
T
S
Y
L
S
F
-----
N
Q
V
I
K
L
N
D
V
-
K
R
R
G
ISGV
T
L
------------------
T
D
I
N
V
A
-
D
Q
L
-------------------
G
Y
K
I
--
K
L
---
I
G
K
G
I
Y
E
-
N
G
------------
K
V
N
A
S
V
E
P
T
-
L
----
I
D
K
K
H
---
Q
L
A
A
V
E
D
E
Y
-
N
A
I
Y
V
I
G
D
A
V
------------------------
G
D
T
--
M
F
Y
G
K
G
A
G
S
L
A
T
G
S
A
V
V
--
S
D
L
L
N
-----
V
A
L
F
F
E
S
T
L
P
P
-------
H
F
---
E
L
K
T
D
---
K
T
R
E
M
E
K
S
N
F
F
---------
V
V
V
----
N
H
V
----------
K
G
S
-----
I
E
N
F
E
N
E
L
K
A
-----
I
L
P
----
F
H
-
R
S
L
R
V
A
----
N
Y
D
N
Q
S
Y
A
A
V
I
V
G
L
----
E
S
----
S
P
E
E
L
I
T
K
H
G
Y
EVD
K
V
Y
P
V
E
GV--------------------------------------------------------------------------------------------
36
Fugue
58.21
15%
14
- C2 -
-
3C2W
1
BPHY_PSEAE
A:
[5-494]
-----------------------------------------TPVTLANC
E
D
E
P
I
H
V
P
G
A
I
Q
P
H
G
A
L
V
T
L
R
ADG
M
V
L
A
A
S
E
----------
N
I
Q
A
LLG
F
V
A
S
P
G
S
Y
L
T
Q
-------------
E
Q
VG
P
E
V
-----
L
R
M
L
E
E
-
G
L
T
G
N
G
P
W
S
N
S
V
E
T
R
I
GE
H
L
--
F
D
V
-----
I
G
H
S
-
Y
-
K
E
V
F
Y
L
E
F
E
I
R
T
A
D
T
L
-
S
----
I
T
S
F
T
L
N
A
Q
R
I
I
A
Q
--------------------
V
-
Q
L
HND
T
A
S
L
L
S
N
V
T
D
E
L
R
R
M
T
G
Y
D
R
-------
V
M
A
Y
R
F
R
HDDSG
E
V
V
A
E
S
R
R
E
D
L
E
----
S
Y
L
G
Q
R
Y
P
A
--
S
D
I
P
A
Q
A
R
R
L
Y
---
I
Q
N
P
I
R
L
I
A
D
---------------
V
---------------
A
-----------------------------------
Y
T
P
M
R
V
F
P
A
L
N
P
E
T
N
E
S
F
D
L
S
Y
S
V
LRSVS
P
I
H
C
E
Y
L
T
N
M
G
V
R
A
----
S
M
------------------
S
I
S
I
V
V
-
G
G
----------------------
K
L
--
W
G
---
L
F
S
C
H
H
M
S
P
K
------------
L
I
P
Y
P
V
R
M
S
-
F
----
Q
I
F
S
Q
---
V
C
S
A
I
V
E
R
L
E
Q
G
R
I
A
E
L
L
R
V
S
--------
T
E
R
R
L
A
L
-------
A
R
R
A
----
R
D
A
D
D
L
F
G
A
L
A
H
P
D
D
GI
A
A
L
I
P
CD
G
A
L
V
M
L
G
G
R
T
L
S
I
R
GDF
E
R
Q
A
G
N
V
L
Q
R
L
Q
R
D
---
P
E
R
D
I
Y
H
T
D
N
W
CC
G
------
V
L
A
----
I
R
F
HRQES
G
W
I
F
W
F
R
H
E
--
E
V
H
R
I
R
W
G
G
K
P
E
-----
K
L
L
TIGP
S
G
-
P
R
L
T
P
-----
R
G
S
F
E
A
W
E
E
V
V
R
G
H
STPW
S
E
----
T
D
L
A
I
A
E
K
L
R
L
D
L
M
E
L
C
L------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
49.33
23%
-22
- C7 -
-
5HIK
2
?
A:
[137-283]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
W
M
N
K
D
I
H
D
K
F
D
A
I
V
C
L
G
N
S
-----
F
T
H
L
-
F
D
E
G
-
D
R
R
K
----
A
L
A
E
F
Y
A
L
LKHD
G
V
L
L
L
D
Q
R
N
Y
D
A
I
L
-
D
D
----------------------
S
K
--
H
A
---
H
Y
Y
C
G
D
T
-
V
S
------------
V
Y
P
E
H
V
D
E
G
-
L
A
R
F
K
Y
E
F
S
D
G
S
V
Y
N
L
N
M
F
P
L
R
-
K
D
Y
T
R
Q
L
L
H
E
V
--------
G
F
Q
E
I
N
T
-------
L
G
D
F
--
K
E
T
Y
K
E
D
E
P
D
F
F
L
H
V
A
E
--
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
48.68
23%
-24
- C7 -
-
5HIM
4
?
A:
[137-283]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
W
M
N
K
D
I
H
D
K
F
D
A
I
V
C
L
G
N
S
-----
F
T
H
L
-
F
D
E
G
-
D
R
R
K
----
A
L
A
E
F
Y
A
L
LKHD
G
V
L
L
L
D
Q
R
N
Y
D
A
I
L
-
D
D
----------------------
S
K
--
H
A
---
H
Y
Y
C
G
D
T
-
V
S
------------
V
Y
P
E
H
V
D
E
G
-
L
A
R
F
K
Y
E
F
S
D
G
S
V
Y
N
L
N
M
F
P
L
R
-
K
D
Y
T
R
Q
L
L
H
E
V
--------
G
F
Q
E
I
N
T
-------
L
G
D
F
--
K
E
T
Y
K
E
D
E
P
D
F
F
L
H
V
A
E
--
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
48.62
17%
50
* C4 *
-
4BHW
1
EP300_HUMAN
A:
[14-576]
--------------------------------------------------
K
K
I
F
K
P
E
E
L
R
Q
A
L
M
P
T
L
E
A
----
L
Y
R
Q
D
P
E
----------
S
L
P
F
---
R
Q
P
V
D
P
Q
L
L
G
I
PDYFDIVK
S
P
M
D
L
S
T
----
I
-----
K
R
K
L
D
T
G
Q
Y
Q
E
P
W
Q
Y
V
D
D
I
W
L
M
F
--
N
N
--
A
W
L
Y
NRKT
S
R
V
Y
-
K
-
Y
C
S
K
L
S
E
V
F
E
Q
E
I
D
P
V
-
M
----
Q
S
L
G
Y
C
C
G
R
K
L
E
F
S
PQTLCCYGKQL
C
T
I
P
R
D
A
T
Y
Y
-
S
-----
Y
Q
N
R
Y
H
F
C
E
K
C
F
N
E
I
Q
G
E
S
-------
V
S
------------
L
G
D
D
P
S
Q
P
Q
T
T
I
N
K
E
Q
F
S
K
R
K
N
D
--
T
L
D
P
E
L
F
V
E
C
T
---
E
C
G
R
K
M
H
Q
I
C
---------------
V
---------------
L
HHEIIWPAGFVC
D
G
C
L
K
K
S
ARTRKENKFSAKRLPS
T
R
L
G
T
F
L
E
N
R
V
N
D
F
L
R
R
Q
N
H
P
E
S
G
-----
E
V
T
V
R
V
V
H
A
-
S
D
K
T
----
V
E
------------------
V
K
P
G
M
K
-
A
R
F
VDSGEMAE
S
F
P
Y
R
T
K
A
L
F
A
F
E
E
I
--
D
G
V
D
L
C
F
F
G
M
H
V
-
Q
E
Y
G
SDCPPPNQR
R
V
Y
I
S
Y
L
D
S
V
H
F
----
F
R
P
K
C
---
L
R
T
A
V
Y
H
E
I
-
L
I
G
Y
L
E
Y
V
K
K
L
--------
G
Y
T
T
G
H
I
WACPPSE
G
D
D
Y
--
I
F
H
C
H
P
P
D
Q
K
I
P
K
P
K
R
L
--
Q
E
W
F
K
-----
K
M
L
D
K
A
V
S
E
R
I
V------
H
D
Y
K
D
I
F
K
Q
A
---
T
E
D
R
L
T
S
A
K
E
L
P
Y
F
E
GD
F
W
P
N
V
L
----
E
E
S
----------
I
K
E
S
GG
S
G
S
Q
K
L
Y
A
T
M
E
K
H
KEV
F
F
V
I
R
LI-
A
G
-
P
A
A
N
S
L
P
P
I
V
D
P
D
P
L
I
P
C
D
L
M
D
G
R
-----
D
----
A
F
L
T
L
A
R
D
K
H
L
EFSS
L
R
R
A
Q
W
S
T
M
C
M
L
V
E
L
H
T
Q
S
Q
D------------------------------------------------------------------------------
3
PsiBlast_PDB
48.51
23%
-25
- C7 -
-
5HIJ
-
?
A:
[137-283]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
W
M
N
K
D
I
H
D
K
F
D
A
I
V
C
L
G
N
S
-----
F
T
H
L
-
F
D
E
G
-
D
R
R
K
----
A
L
A
E
F
Y
A
L
LKHD
G
V
L
L
L
D
Q
R
N
Y
D
A
I
L
-
D
D
----------------------
S
K
--
H
A
---
H
Y
Y
C
G
D
T
-
V
S
------------
V
Y
P
E
H
V
D
E
G
-
L
A
R
F
K
Y
E
F
S
D
G
S
V
Y
N
L
N
M
F
P
L
R
-
K
D
Y
T
R
Q
L
L
H
E
V
--------
G
F
Q
E
I
N
T
-------
L
G
D
F
--
K
E
T
Y
K
E
D
E
P
D
F
F
L
H
V
A
E
--
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
48.45
23%
-10
- C7 -
-
5HII
3
?
A:
[137-283]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
W
M
N
K
D
I
H
D
K
F
D
A
I
V
C
L
G
N
S
-----
F
T
H
L
-
F
D
E
G
-
D
R
R
K
----
A
L
A
E
F
Y
A
L
LKHD
G
V
L
L
L
D
Q
R
N
Y
D
A
I
L
-
D
-----------------------
S
K
--
H
A
---
H
Y
Y
C
G
D
T
-
V
S
------------
V
Y
P
E
H
V
D
E
G
-
L
A
R
F
K
Y
E
F
S
D
G
S
V
Y
N
L
N
M
F
P
L
R
-
K
D
Y
T
R
Q
L
L
H
E
V
--------
G
F
Q
E
I
N
T
-------
L
G
D
F
--
K
E
T
Y
K
E
D
E
P
D
F
F
L
H
V
A
E
--
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
47.48
23%
-0
- C7 -
-
5HIL
4
?
A:
[137-283]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
W
M
N
K
D
I
H
D
K
F
D
A
I
V
C
L
G
N
S
-----
F
T
H
L
-
F
D
E
G
-
D
R
R
K
----
A
L
A
E
F
Y
A
L
LKHD
G
V
L
L
L
D
Q
R
N
Y
D
A
I
L
-
D
-----------------------
S
K
--
H
A
---
H
Y
Y
C
G
D
T
-
V
S
------------
V
Y
P
E
H
V
D
E
G
-
L
A
R
F
K
Y
E
F
S
D
G
S
V
Y
N
L
N
M
F
P
L
R
-
K
D
Y
T
R
Q
L
L
H
E
V
--------
G
F
Q
E
I
N
T
-------
L
G
D
F
--
K
E
T
Y
K
E
D
E
P
D
F
F
L
H
V
A
E
--
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
47.27
23%
-20
- C7 -
-
5GWX
2
?
A:
[137-283]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
W
M
N
K
D
I
H
D
K
F
D
A
I
V
C
L
G
N
S
-----
F
T
H
L
-
F
D
E
G
-
D
R
R
K
----
A
L
A
E
F
Y
A
L
LKHD
G
V
L
L
L
D
Q
R
N
Y
D
A
I
L
-
D
D
G
-------------------
Y
S
S
K
--
H
A
---
H
Y
Y
C
G
D
T
-
V
S
------------
V
Y
P
E
H
V
D
E
G
-
L
A
R
F
K
Y
E
F
S
D
G
S
V
Y
N
L
N
M
F
P
L
R
-
K
D
Y
T
R
Q
L
L
H
E
V
--------
G
F
Q
E
I
N
T
-------
L
G
D
F
--
K
E
T
Y
K
E
D
E
P
D
F
F
L
H
V
A
E
--
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
46.74
23%
-13
- C7 -
-
5H02
2
?
A:
[136-282]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
W
M
N
K
D
I
H
D
K
F
D
A
I
V
C
L
G
N
S
-----
F
T
H
L
-
F
D
E
G
-
D
R
R
K
----
A
L
A
E
F
Y
A
L
LKHD
G
V
L
L
L
D
Q
R
N
Y
D
A
I
L
-
D
D
G
-------------------
Y
S
S
K
--
H
A
---
H
Y
Y
C
G
D
T
-
V
S
------------
V
Y
P
E
H
V
D
E
G
-
L
A
R
F
K
Y
E
F
S
D
G
S
V
Y
N
L
N
M
F
P
L
R
-
K
D
Y
T
R
Q
L
L
H
E
V
--------
G
F
Q
E
I
N
T
-------
L
G
D
F
--
K
E
T
Y
K
E
D
E
P
D
F
F
L
H
V
A
E
--
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
46.43
12%
29
* C6 *
-
3N6R
1
?
A:
[2-681]
FNK
I
L
I
ANRG
E
I
A
C
R
V
I
K
T
A
R
K
M
GIS
T
V
A
I
Y
S
DADKQA
L
H
V
Q
M
AD
E
A
V
H
I
G
P
P
P
A
N
Q
S
Y
I
V
I
D
K
V
M
A
A
I
----
R
A
T
G
A
Q
A
VHPGYGFLSE
N
S
K
F
---
A
E
A
L
E
A
E
G
V
I
F
-------------
V
G
----
P
-----
P
K
G
A
I
E
-
A
M
G
D
K
I
T
S
K
K
I
A
Q
E
A
N
--
V
S
--
T
V
P
-----
G
V
T
Q
-
P
-
R
H
I
E
I
Q
V
L
C
D
S
H
G
N
G
I
-
Y
L
G
E
R
E
C
S
I
Q
R
R
N
Q
K
V
V
E
E
--------------------
A
P
S
-----
P
F
L
D
E
A
T
R
R
A
M
G
E
Q
A
V
A
L
A
KAVGYA
S
A
G
T
V
E
-------
F
I
V
---
D
G
Q
K
N
F
Y
F
--
L
E
M
N
---
T
R
--
L
Q
V
E
H
P
V
T
E
L
I
T
GV
D
L
V
E
Q
M
I
R
V
A
---------------
A
GEPLSITQGDVKL
T
G
W
-----------------------------------
A
I
E
N
R
L
Y
A
E
D
P
Y
R
G
F
L
P
--
S
I
G
R
L
-----
T
R
Y
R
P
P
A
E
A
-
A
V
R
N
----
D
T
------------------
G
V
Y
E
-
G
-
G
E
I
-------------------
S
M
Y
Y
--
D
P
---
M
---
I
A
K
-
L
C
------------
T
W
A
P
T
R
A
A
A
-
I
----
E
A
M
R
I
---
A
L
D
S
F
E
V
E
G
-
I
G
H
N
L
P
F
L
S
A
V
--------
M
D
H
P
K
F
I
-------
S
G
D
M
TT
A
F
I
A
E
E
Y
P
E
G
F
E
G
V
N
L
P
--
E
T
D
L
R
-----
R
V
A
A
A
A
A
A
M
H
R
-------
V
A
E
I
R
R
T
R
V
S
GRM
D
N
H
E
R
R
V
G
T
E
W
---------
V
V
T
L
QGA
D
F
P
----------
V
T
I
A
--
A
D
H
D
G
S
T
V
S
F
D
D
-----
G
S
S
----
M
R
-
V
T
S
D
W
-----
T
P
G
D
Q
L
A
N
L
M
V
D
G
A
----
P
L
----
V
L
K
V
G
K
I
S
G
G
F
R
I
R
T
R
G
A
D
L
K
V
H
V
R
T
P
R
Q
A
E
L
A
R
L
M
P
E
K
L
P
P
D
T
S
KMLLCPMPGLIVKVDVEVG
Q
E
V
Q
EGQAL
C
T
I
E
A
MK
M
E
N
I
L
R
A
E
K
K
G
V
V
AKINASAG
N
S
L
A
V
DDVIMEFE
10
HHSearch
41.40
20%
-193
- C7 -
-
3CT0
1
GP13_BPPH2
A:
[12-52]
----------------------------------------------------------------------------------------------------------------------------------------------
S
E
M
K
V
N
A
Q
Y
I
L
N
Y
L
--
S
S
--
N
G
W
-------
T
K
-
Q
-
A
I
C
G
M
L
G
N
M
Q
S
E
S
T
I
N
-
P
----
G
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
41.18
17%
53
* C5 *
-
4TVS
-
TOIP1_HUMAN
A:
[8-231]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
E
T
T
A
V
Q
E
F
Q
--
N
Q
M
N
Q
L
K
N
K
Y
Q
G
Q
D
E
K
L
W
K
R
S
Q
---
T
F
L
E
K
H
L
N
S
S
HPRSQ
P
A
I
L
L
L
T
A
A
R
D
---------------
A
-----------------------------------
E
E
A
L
R
C
L
S
E
Q
I
A
D
A
Y
S
S
F
R
S
V
R
A
I
-----
R
I
D
-
G
T
D
K
A
-
T
Q
D
S
----
D
T
------------------
V
K
L
E
V
D
-
Q
E
L
-------------------
S
N
G
F
K
N
G
Q
---
N
A
A
V
V
H
R
-
F
E
------------
S
F
P
A
G
S
T
L
I
-
F
----
Y
K
Y
C
D
---
H
E
--------
N
A
A
F
-----------------
K
D
V
A
L
-------
V
L
T
V
--
L
L
E
E
E
T
L
G
T
S
L
G
L
K
E
V
E
--
E
K
V
R
D
-----
F
L
K
V
K
F
T
N
S
N
T
-------
P
N
S
Y
N
H
M
D
P
D
---
K
L
N
G
L
W
S
R
I
S
H
---------
L
V
L
----
P
V
Q
----------
P
E
N
A
--
L
K
R
G
I
C
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
41.18
20%
-196
- C7 -
-
3CT5
1
GP13_BPPH2
A:
[12-52]
----------------------------------------------------------------------------------------------------------------------------------------------
S
E
M
K
V
N
A
Q
Y
I
L
N
Y
L
--
S
S
--
N
G
W
-------
T
K
-
Q
-
A
I
C
G
M
L
G
N
M
Q
S
E
S
T
I
N
-
P
----
G
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
40.51
19%
-32
- C7 -
-
1JHL
-
LYSC_PHACO
A:
[8-45]
-------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
A
A
M
--
K
R
--
M
G
L
-----
D
N
Y
R
G
Y
-
S
L
G
N
W
V
C
A
A
K
F
E
S
N
F
N
-
T
----
G
A
T
N
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
40.46
17%
-52
- C5 -
-
5FKV
-
DPO3X_ECOLI
E:
[506-622]
-----------------------------------------------------------------------------------------------------------
T
-------------
P
E
----
L
-----
A
A
K
L
A
A
-
E
A
I
E
R
D
P
W
A
A
Q
V
S
Q
L
--------
S
L
-----
P
K
L
V
-
E
-
Q
V
A
L
N
-
A
W
K
E
E
S
D
N
A
V
---------
C
L
H
L
R
S
S
Q
R
H
L
--------------------
N
-
N
-----
R
G
A
Q
Q
K
L
A
E
A
L
S
M
L
K
G
S
T
V
-----------
E
-------
L
T
I
V
E
D
D
N
P
A
V
R
T
P
--
L
E
W
R
Q
A
I
Y
E
--
E
K
L
A
Q
A
R
E
S
I
I
---
A
D
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
40.42
19%
-162
- C7 -
-
4OK7
-
?
C:
[15-67]
--------------------------------------------------------------------------------------------------------
M
M
D
I
-------------
N
Q
----
F
-----
R
R
A
S
G
I
-
N
E
Q
L
A
A
R
W
F
P
H
I
T
T
A
M
--
N
E
--
F
G
I
-----
T
-
K
P
-
D
-
D
Q
A
M
F
I
A
Q
V
G
H
E
S
G
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
40.21
19%
-46
- C7 -
-
1LSG
-
LYSC_CHICK
A:
[9-46]
-------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
A
A
M
--
K
R
--
H
G
L
-----
D
N
Y
R
-
G
Y
S
L
G
N
W
V
C
A
A
K
F
E
S
N
F
N
-
T
----
Q
A
T
N
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------