@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : TIDC1_HUMAN: (2018-07-14 )
MEVPPPAPRSFLCRALCLFPRVFAAEAVTADSEVLEERQKRLPYVPEPYYPESGWDRLRELFGKDEQQRISKDLANICKTAATAGIIGWVYGGIPAFIHAKQQYIEQSQAEIYHNRFDAVQSAHRAATRGFIRYGWRWGWRTAVFVTIFNTVNTSLNVYRNKDALSHFVIAGAVTGSLFRINVGLRGLVAGGIIGALLGTPVGGLLMAFQKYSGETVQERKQKDRKALHELKLEEWKGRLQVTEHLPEKIESSLQEDEPENDAKKIEALLNLPRNPSVIDKQDKD
Atome Classification :
(20 SA)
------------------------.........10........20...-.....30......--..40........50-....-....-.60........70....------------....80....---..-------------------------..90........100.......110.....-----------------..120-....--.....130....---------.....140.......---------------150.......160------.-.-....--...170..--------------..---------------.-----..180....-....190.......-------------.200--------........210.----------...---------------...220-.......230.......240--.........250.......260.......270...--...-.280...----------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
------------------------MEVPPPA
P
R
S
F
L
C
R
A
L
C
L
F
P
R
V
F
A
-
A
EAVTA
D
S
E
V
L
E
E
--
R
Q
K
RLPYVPEPYY--PES
G
-
W
D
R
L
-
R
E
L
FG
K
D
E
Q
Q
R
I
S
K
D
L
A
------------
N
I
C
K
T
A
A
T
A
G
---
I
I
-------------------------
G
W
V
YGG
I
P
A
F
I
H
A
K
Q
Q
Y
I
E
Q
S
Q
A
E
I
Y
H
N
R
F
-----------------
D
A
V
---
Q
S
A
H
--
R
A
A
TRG--
F
I
RY---------
G
W
RWGW
R
T
A
V
F
V
T
I
F
---------------NTVNT
S
L
N
V
Y
R--------
N
-
K
-
D
A
L
S
--
H
F
V
I
A
GAV--------------TG---------------
S
-----
L
F
R
-
I
NVG
L
-
R
G
L
V
A
G
-
G
I
I
G
A
L
L
-------------GTP---------
V
G
G
L
L
M
A
F
Q
KYS----------G
E
T
---------------
V
Q
E
R
K
Q
-
K
D
R
K
A
L
H
E
L
K
L
E
E
WKG
R
L
----
Q
V
T
E
H
L
P
E
K
I
E
S
S
L
QEDEPE
N
D
A
K
K
I
E
A
L
LNLPRN--PSV-IDKQDKD----------------------------------------
29
Fugue
69.24
20%
-17
- C4 -
-
5MG3
-
SECD_ECOLI
D:
[8-619]
------------------------
M
L
N
R
Y
P
L
W
K
Y
V
M
L
I
V
V
I
V
I
G
L
L
Y
A
L
P
N
A
V
Q
Q
N
I
N
I
L
R
N
--
R
V
N
Q
L
G
-
V
A
E
P
V
V
--
Q
R
Q
G
-
A
D
R
I
V
V
E
L
P
G
I
Q
D
T
A
R
A
K
E
I
L
G
ATATLEFRLVNT
N
V
D
Q
A
A
A
A
S
G
---
R
V
PGDSEVKQTREGQPVVLYKRVILTG
D
H
I
T
D
S
T
S
S
Q
D
E
Y
N
Q
P
Q
V
N
I
S
L
D
S
A
G
G
N
I
M
-----------------
S
N
F
---
T
K
D
N
IG
K
P
M
A
T
L
--
F
V
E
Y
KDSGKKDAN
G
R
A
V
L
V
K
Q
E
E
V
I
N
I
A
---------------
N
I
Q
S
R
L
G
N
S
F
R
ITGINNPN
E
-
A
-
R
Q
L
S
--
L
L
L
R
A
G
A
L
IAPIQIVEERTIGP
T
L
---------------
G
-----
M
Q
N
-
I
E
Q
G
L
-
E
A
C
L
A
G
-
L
L
V
S
I
L
F
MIIFYKKFGLIAT
S
A
L
---------
I
A
N
L
I
L
I
V
G
I
M
S
LLPGATLSMP
G
I
A
---------------
G
I
V
L
T
L
-
A
V
A
V
D
A
N
V
L
I
N
E
R
I
K
E
E
L
SNGR
T
V
Q
Q
A
I
D
E
G
Y
R
G
A
F
S
S
I
F
D
A
N
I
T
T
L
I
K
V
I
I
L
Y
A
V
G
--
T
G
A
-
I
K
G
F
A
I
T
TGIGVATSMFTAIVGTRAIVNLLYGGKRVKK---------
27
Fugue
61.66
14%
5
- C3 -
-
4WZI
-
PDE4B_HUMAN
A:
[85-576]
VT
P
F
A
Q
V
L
A
S
L
R
S
V
R
N
N
F
T
IQ
K
L
A
M
E
T
L
E
E
L
D
W
A
L
D
Q
L
E
T
I
Q
T
Y
R
S
V
S
-
E
M
A
S
N
K
F
K
R
M
L
N
R
--
E
L
T
H
L
S
E
M
S
R
C
G
N
--
Q
V
S
E
-
Y
I
S
N
-
T
F
L
-
D
K
E
N
E
D
H
L
A
K
E
L
E
DLNKWGL-----
N
I
F
N
V
A
G
Y
S
H
NR
P
L
T
-------------------------
A
I
M
Y
A
I
F
Q
E
R
D
L
L
K
T
F
R
I
S
S
D
T
F
I
T
Y
M
M
T
L
E
D
H
YHSDVAYHN
S
L
H
A
A
D
V
A
---
Q
S
T
H
--
V
L
L
S
T
P
--
A
L
D
A
---------
V
F
T
D
L
E
I
L
A
A
I
F
A
A
A
I
H
DVDHPGVS
N
Q
F
L
I
N
T
N
S
E
L
A
L
M
Y
N
--------
D
-
E
-
S
V
L
E
N
H
H
L
A
V
G
F
K
L
--------------
L
Q
---------------
E
EHADI
F
M
N
-
L
T
K
K
Q
-
R
Q
T
L
R
K
-
M
V
I
D
M
V
L
-------------
A
T
D
---------
M
S
K
H
M
S
L
L
A
D
L
K
----------
T
M
V
E
T
K
K
V
T
SSG
V
L
L
L
DN
Y
T
D
R
I
Q
-
V
L
R
N
M
V
H
A
A
D
L
S
N
P
T
K
S
L
----
E
L
Y
R
Q
W
T
D
R
I
M
E
E
F
F
Q
Q
G
D
K
E
R
E
R
G
M
E
I
S
P
M
A
D
K
H
--
T
A
C
-
V
E
K
S
Q
V
G
F
I
D
Y
I
V
H
P
L
W
E
T
W
A
D
L
V
QPDA
Q
D
I
L
D
T
L
E
D
N
R
N
W
Y
Q
A
M
IP
28
Fugue
55.63
16%
-8
- C5 -
-
5JJO
-
?
A:
[4-268]
-------------------------------
L
R
P
F
I
C
--------
V
N
E
-
K
D
H
L
P
S
L
D
P
Q
A
D
A
--
W
Y
R
E
A
V
A
L
A
K
P
D
T
--
L
R
P
--
W
D
R
I
-
V
D
L
Y
S
K
A
V
E
R
G
H
W
K
A
M
H
------------
N
L
A
S
L
Y
R
T
--------------------------------
G
W
--
K
D
T
Q
K
A
L
D
L
Y
Q
K
M
I
D
L
K
V
P
Q
G
F
Y
D
M
A
-----------------
A
M
I
GNR
A
G
V
K
--
N
P
A
T
D
G
LT
F
L
D
K
---------
A
A
S
L
G
N
P
P
A
L
T
E
L
G
R
---------------
L
Y
I
Y
V
A
-------------
G
-
Q
-
D
E
L
G
--
L
K
Y
T
N
C
A
A
--------------
G
Q
---------------
G
-----
Y
A
P
-
A
N
Y
E
L
-
A
M
Y
Y
R
L
---
V
A
H
N
Y
-------------
P
K
A
---------
A
G
Y
Y
L
L
A
A
S
Q
G
N
----------
D
D
A
---------------
A
F
F
M
S
G
V
F
D
K
T
S
P
D
V
D
R
M
--
W
Y
A
P
D
----
E
K
L
H
K
L
Y
D
G
I
Y
D
Q
L
A
A
D
-
P
D
L
R
F
P
N
L
I
K
D
H
P
L
P
P
H
--
P
T
Q
G
Y
D
A
D
R
P
D
----------------------------------------
26
Fugue
49.00
13%
-61
- C2 -
-
3R9F
2
?
A:
[8-187]
-------------------------------------------------------------------------
D
V
S
L
--
T
P
S
G
-
I
K
V
N
-
D
E
I
T
L
L
Y
P
A
L
K
Y
A
E
E
L
Y
------------
L
L
I
N
Q
N
K
I
N
F
---
I
K
-------------------------
S
M
A
W
P
A
F
V
N
N
I
S
D
S
V
S
F
I
E
Q
S
M
I
D
N
Q
N
E
K
A
-----------------
L
I
L
---
F
I
K
Y
--
K
T
K
I
A
G
--
V
V
S
F
---------
N
I
I
D
H
A
N
K
T
A
Y
I
G
Y
W
L
G
ANFQGKG
I
V
T
---
N
A
I
N
K
L
I
Q
E
Y
G
--------
D
-
S
-
G
V
I
K
--
R
F
V
I
K
C
I
V
--------------
D
N
---------------
K
-----
K
S
N
-
A
T
A
L
R
-
C
G
F
T
L
E
-
G
V
L
Q
K
---------------
A
E
I
---------
L
N
G
V
S
Y
D
Q
N
I
Y
S
----------
K
V
I
------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
47.71
25%
-48
- C7 -
-
2ZSI
1
GID1A_ARATH
A:
[173-253]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
---------------
N
W
V
N
S
R
S
W
L
K
S
--------
K
-
K
-
D
S
K
V
--
H
I
F
L
A
G
D
S
--------------
S
G
---------------
G
-----
N
I
A
-
H
N
V
A
L
-
R
A
G
E
S
G
I
D
V
L
G
N
I
L
-------------
L
N
P
---------
M
F
G
--------
G
----------
N
E
R
---------------
T
E
S
E
K
S
-
L
D
G
K
Y
F
V
T
V
R
D
R
D
W
------------------------------------------------------------------------------------------------
25
Fugue
46.83
20%
-24
- C6 -
-
3HG9
-
?
A:
[9-127]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
E
V
---------------
D
T
L
A
R
S
L
L
L
Y
R
--------
S
-
R
-
L
A
E
Y
--
A
H
A
N
P
G
F
S
--------------
G
S
PADSALGLP------
A
-----
W
F
R
-
K
P
V
R
L
-
Q
G
Y
I
A
A
-
G
T
S
Y
A
F
I
-------------
A
S
P
---------
P
A
G
L
A
A
A
V
D
T
G
T
----------
E
S
D
---------------
L
V
G
V
R
R
-
N
G
Q
L
V
T
R
R
L
G
A
T
A
----
I
----
A
L
P
A
P
I
P
E
G
A
V
V
A
V
K
E
G
H
H
---------------------------------------------------------------------
3
PsiBlast_PDB
46.52
25%
-38
- C7 -
-
2ZSH
1
GID1A_ARATH
A:
[173-253]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
---------------
N
W
V
N
S
R
S
W
L
K
S
--------
K
-
K
-
D
S
K
V
--
H
I
F
L
A
G
D
S
--------------
S
G
---------------
G
-----
N
I
A
-
H
N
V
A
L
-
R
A
G
E
S
G
I
D
V
L
G
N
I
L
-------------
L
N
P
---------
M
F
G
--------
G
----------
N
E
R
---------------
T
E
S
E
K
S
-
L
D
G
K
Y
F
V
T
V
R
D
R
D
W
------------------------------------------------------------------------------------------------
12
HHSearch
44.16
15%
-52
- C7 -
-
5XTD
-
NDUAB_HUMAN
V:
[12-113]
-----------------------------------------------------------------------------------------------------
I
P
D
G
T
------------
D
C
H
R
K
A
Y
S
T
T
---
S
I
-------------------------
A
S
V
A
G
L
T
A
A
A
Y
R
V
T
L
N
--
P
P
G
---
T
------------------------------------
F
L
E
G
---
V
A
K
---------
V
G
Q
Y
T
F
T
A
A
A
V
G
A
V
F
---------------
G
L
T
T
C
I
S
A
H
V
R
--------
E
-
K
P
D
D
P
L
--
N
Y
F
L
G
G
C
A
--------------
G
G
---------------
L
-----
T
L
G
-
A
R
T
H
N
Y
G
I
G
A
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
41.89
12%
-80
- C7 -
-
5XTD
-
NDUAB_HUMAN
V:
[18-118]
-------------------------------------------------------------------------------------------------------
C
H
R
------------
K
A
Y
S
T
T
S
I
A
S
---
V
A
-------------------------
G
L
T
A
A
A
Y
R
V
T
L
N
P
P
G
T
F
L
E
G
----
V
--------------------------------------
A
K
--
V
G
Q
Y
---------
T
F
T
A
A
A
V
G
A
V
F
G
L
T
T
---------------
C
I
S
A
H
V
R
E
K
P
D
--------
D
P
L
-
N
Y
F
L
--
G
G
C
A
G
G
L
T
--------------
L
G
---------------
A
-----
R
T
H
N
Y
G
I
G
A
-
A
A
C
V
Y
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
40.28
20%
57
- C7 -
-
5AJS
-
THA11_HUMAN
A:
[252-314]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
E
E
----------
E
L
L
---------------
R
K
L
N
E
Q
-
R
D
I
L
A
L
M
E
V
K
M
K
E
M
K
G
S
I
----
R
H
L
R
L
T
E
A
K
L
R
E
E
L
R
E
K
D
R
L
L
A
M
A
V
I
R
K
K
H
G
M
--------------------------------------------------------
5
PsiBlast_PDB
38.38
26%
10
- C7 -
-
2LST
-
?
A:
[55-122]
----------------------------------------------
F
V
-
V
A
S
V
S
V
D
T
P
E
G
Q
E
L
A
R
R
Y
R
V
P
G
T
P
T
F
V
F
L
V
P
K
A
G
A
W
E
E
V
-
G
R
L
F
G
S
R
P
R
A
E
F
L
K
E
L
R
------------
Q
V
C
V
K
G
G
A
C
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
37.72
8%
-94
- C7 -
-
1F8V
-
?
E:
[2-13]
---------------------------------------------------------------------------------
K
F
-
W
E
G
V
-
L
R
V
L
N
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
36.70
12%
31
* C7 *
-
4X01
4
COM1_SCHPO
A:
[6-54]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
V
----------
H
W
S
---------------
I
V
Y
R
Q
L
-
G
N
L
L
E
Q
Y
E
V
E
I
A
R
L
K
S
Q
L
----
V
L
E
K
K
L
R
I
Q
V
E
K
E
M
E
S
V
K
T
K
--------------------------------------------------------------------
2
PsiBlast_PDB
36.48
31%
14
- C7 -
-
1EA0
-
GLTB_AZOBR
A:
[388-463]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
E
M
I
A
V
D
L
Q
S
----------
G
K
L
---------------
Y
R
D
R
E
L
-
K
D
----
H
L
A
T
L
K
P
W
D
K
W
V
----
Q
N
T
T
H
L
D
E
L
V
K
T
A
S
L
K
G
E
P
-
S
D
M
D
K
A
E
-------------------------------------------------------------
1
PsiBlast_PDB
36.39
31%
14
- C7 -
-
2VDC
-
GLTB_AZOBR
A:
[388-446]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
E
M
I
A
V
D
L
Q
S
----------
G
K
L
---------------
Y
R
D
R
E
L
-
K
D
----
H
L
A
T
L
K
P
W
D
K
W
V
----
Q
N
T
T
H
L
D
E
L
V
K
T
A
S
L
K
G
E
P
-
S
D
M
D
K
A
E
-------------------------------------------------------------
10
PsiBlast_PDB
32.67
30%
144
- C7 -
-
4TQL
-
?
A:
[46-108]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
E
V
K
Q
-
E
V
E
K
A
I
E
E
M
K
------------
K
L
Y
D
E
A
K
K
K
I
E
Q
M
I
Q
Q
I
K
Q
G
G
D
K
Q
K
M
E
E
L
L
K
R
A
K
E
E
M
K
K
V
-
K
D
K
M
E
K
-----------------------------------------
8
PsiBlast_PDB
31.45
25%
-1
- C7 -
-
4KJS
-
CHAA_BACSU
A:
[24-145]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
P
S
A
V
L
F
A
V
Y
---------------
C
V
T
I
I
A
L
A
S
Y
M
--------
G
-
R
-
A
T
E
S
--
L
S
I
----
R
--------------
I
G
G
L
L
N
A
T
F
G
N
A
V
E
L
I
I
S
-----
M
F
A
-
L
K
E
G
L
-
T
G
I
V
L
A
-
S
L
T
G
S
V
L
-------------
G
N
L
LL
V
A
G
L
S
F
F
V
G
G
L
K
Y
A
R
Q
E
F
N
-------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
29.26
17%
78
- C7 -
-
4JQU
2
B:
[1-54]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
L
D
K
F
H
VDL-------
N
E
D
---------------
M
S
N
L
S
F
-
K
D
L
D
I
E
E
R
K
R
L
L
V
W
Q
A
R
K
----
N
L
E
T
K
L
Q
S
D
K
D
L
Q
S
L
L
T
-----------------------------------------------------------------------
17
HHSearch
28.78
40%
-
- C1 -
-
4H62
-
V:
[10-19]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
K
Q
I
E
E
L
L
D
---------------------------------------------------------
22
Fugue
28.54
36%
-
- C7 -
-
4MGP
-
A:
[1-22]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
G
K
F
L
H
A
A
K
K
F
A
K
A
F
V
A
E
I
M
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------