@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0113: (2017-12-15 )
MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLIYFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQEYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFMFSYILLFVQSYLGSNTAWIGNRRLIIDDEFEKILLSKSYVKEISSARYSEYLTCEYKNLTPIILIAIFENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYDNEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCVPSQYDRFFYKDRPYIFSRKSPIKG
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------------------------------.........10--------.........20.....----...30........40.----.....------..50..--......60........70........80........90........100....-...110.-...-...120--------.........130.......140...----....150----......-----.160.......170.--....----------..180.----......190...--..-...---.200.......210..-------.....220.--.------....-.-----230...-....---240...--.-...250...---.---------...260.....----------..270-.........280.......290..--......300.......310..-----.....320-.....--------.--------..-------.330-.----......340.......350--------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------------------MKD
D
Q
K
Y
L
L
A
---------
G
L
Y
S
L
L
V
A
I
F
Y
F
PLID----SK
G
I
F
V
S
I
L
M
A
V
L
L
L
Y
----
L
I
Y
F
I
------
A
T
V
I
H
I
--
V
I
I
K
F
I
R
KKS
F
K
Y
L
V
L
Y
P
F
TYDG
S
W
R
F
Q
P
I
N
L
L
Y
F
P
E
M
V
R
D
VI
P
I
N
L
V
Q
E
Y
CQ-GQ
P
Y
G
L
L
-
K
K
M
-
L
K
R
I
----------
R
L
S
R
E
I
A
L
L
L
A
T
I
I
V
Y
F
F
THRI
L
P
L
----
S
V
F
T
F
M
F
----
S
Y
I
L
L
F
-----
V
Q
S
Y
LGSN
T
A
W
IGN
R
--
R
L
I
I----------
D
D
E
F
E
K
----
I
L
L
S
K
S
Y
--
V
K
E
--
I
S
-
S
A
R
---
Y
S
E
Y
L
T
C
E
YKNL
T
P
I
I
-------
L
I
A
I
F
E
N
L
L
--
D
------
S
Y
L
L-Q-----NQSEV
D
-
L
D
I
F
---
Y
K
V
L
P
L
--
L
-
Y
K
EKYTMG
F
---
N
---------
Y
F
V
S
L
N
Y
L
L
Y
K
----------V
G
F
---
L
G
I
I
YD
N
E
A
L
R
D
L
S
K
Q
Y
L
N
K
-
N
I
S
--
E
LQDGSFEGG
I
Q
D
AVAS
K
Q
I
V
-----
V
I
N
E
F
I
---
A
C
L
NS--------R--------CV-------P
S
Q
Y
-
D
----
R
F
F
YKDR
P
Y
I
FSRKSPIKG--------
15
Fugue
60.81
23%
-17
- C8 -
-
2Y38
2
LAMA5_MOUSE
A:
[8-398]
---------------------------------------------------------------------------------------------------------------G
F
S
L
H
P
P
Y
F
N
L
A
---------
E
G
A
R
I
T
A
S
A
T
C
H
P
V
S
N
AIDG
T
E
R
W
W
Q
S
P
P
L
S
R
G
L
E
Y
N
E
V
N
V
T
L
D
L
------
G
Q
V
F
H
V
A
Y
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L
I
K
F
A
N
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P
R
P
D
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E
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D
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-
T
Y
Q
P
W
Q
F
F
A
S
S
------------
K
R
D
C
L
-
E
R
---
F
G
-
P
R
T
-
L
E
R
I
TQDD
D
V
I
C
T
T
E
Y
S
R
I
V
P
L
E
N
G
E
I
V
V
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L
V
N
G
R
P
G
A
L
NFSY
S
P
L
L
R
D
F
----
T
K
A
T
N
I
-----
R
L
R
F
L
R
T
N
T
L
---
L
G
--
H
L
M
G
----------
K
A
L
R
D
P
----
T
V
T
R
R
Y
Y
Y
S
I
K
D
--
I
S
I
G
G
R
C
V
C
H
G
H
A
D
V
C
D
A
K
D
P
-------------------
L
--
D
------
P
F
R
L
-
Q
CACQH
N
T
C
G
G
S
-
C
D
R
C
CPG
F
N
Q
Q
P
-----
W
K
P
A
T
T
D
S
A
---
N
---------
E
C
Q
S
C
N
-----------------
C
---
H
G
H
A
Y
D
C
Y
Y
D
P
E
V
D
R
R
E
A
S
Q
-
N
------
Q
D
N
V
Y
Q
G
G
G
V
C
L
D
C
Q
H
H
T
T
-----
G
I
N
-------
C
--
E
--------
R
--------
C
L
-------
P
G
F
F
R
A
----
P
D
Q
P
L
D
S
P
H
V
C
R
P
A
A
A
H
----------
18
Fugue
60.24
20%
-48
* C9 *
-
5IX1
1
MORC3_MOUSE
A:
[3-450]
-------------------------------------------------------------------------------------------------------------GIR
L
S
A
L
C
P
K
F
L
H
T
N
S
TSHTW
P
F
S
A
V
A
E
L
I
D
N
A
Y
D
P
D
V
N
----
A
K
Q
I
W
I
D
K
T
V
I
S
D
H
I
C
----
L
T
F
T
D
NGNGMT
A
D
K
L
H
K
--
M
L
S
F
G
F
S
D
K
V
T
M
N
G
H
V
P
V
G
L
Y
G
N
G
F
K
S
G
S
M
R
L
------
G
K
D
A
M
V
F
T
K
N
G
E
----
T
M
S
V
G
F
L
S
Q
T
Y
-
L
E
V
I
----------
K
A
E
H
----
V
V
V
P
I
V
T
F
N
K
H
R
Q
M
I
N
L
----
T
E
S
K
A
S
L
----
A
A
I
L
E
H
SLFST
E
Q
K
L
L
A
E
L
N
A
I
M
G
K
K
G
T
R
I
I
I
W
NLRSYKNAT
E
F
D
F
E
K
DKY
D
I
R
I
P
E
D
Y
--
K
K
Q
EI
A
P
-
E
S
D
---
Y
S
L
R
A
Y
C
S
I
L
Y
L
K
P
R
M
-------
Q
I
I
I
R
G
Q
K
V
--
K
------
T
Q
L
V
-
S
-----
K
S
L
A
Y
I
-
E
R
D
V
---
Y
R
P
K
F
L
--
T
-
R
T
V
R
I
T
F
G
F
---
N
CRNKDHY
G
I
M
M
Y
H
K
N
R
L
I
K
A
YEKVGCQNMG
V
G
V
---
V
G
I
I
E
C
N
F
L
K
P
T
H
N
K
Q
D
F
D
Y
T
N
E
Y
--
R
L
T
I
L
A
L
G
E
K
L
N
D
Y
W
N
E
M
K
K
R
-----
P
D
Q
T
W
V
Q
C
D
A
C
L
K
W
--------
R
--------
K
L
-------
P
D
G
I
-
D
QLPE
K
W
Y
C
S
N
N
P
D
P
Q
F
R
N
C
E
V
P
E
E
P
E
D
E---
22
Fugue
36.39
10%
-28
- C6 -
-
3PY7
1
MALE_ECOLI (first)
A:
[3-516]
IEEG
K
L
V
I
W
I
N
GDKG
Y
N
G
L
A
E
V
G
K
K
F
E
K
D
TG
I
K
V
T
V
E
H
P
DK
L
E
E
K
F
P
Q
V
A
A
T
GDGPD
I
I
F
W
AHDR
F
G
G
Y
A
Q
S
GLL
A
E
I
T
P
A
A
A
F
Q
D
K
L
Y
P
F
T
W
D
A
V
RYNGKLI
A
Y
P
I
A
V
E
A
L
S
L
I
Y
N
K
D
L
L
P
N
---------
P
P
K
T
W
E
E
I
P
A
L
D
K
E
L
K
----
A
K
G
K
S
A
L
M
F
N
L
Q
E
P
Y
F
----
T
W
P
L
I
------
A
A
D
G
G
Y
--
A
F
K
Y
E
N
G
K
Y
D
I
K
D
V
G
V
D
--
N
A
G
A
K
A
G
L
T
F
L
V
D
L
I
K
N
K
H
M
N
A
D
T
D
Y
S
I
A
E
A
A
F
N
K
G
E
T
A
M
T
I
-
N
G
P
-
W
A
W
S
----------
N
I
D
T
S
A
V
N
Y
G
V
T
V
L
P
T
F
K
G
Q
P
S
K
P
F
----
V
G
V
L
S
A
G
I
N
AA
S
P
N
K
E
L
-----
A
K
E
F
L
E
N
Y
L
L
T
D
E
G
L
--
E
A
V
N
----------
K
D
K
P
L
G
----
A
V
A
L
K
S
Y
--
E
E
E
--
L
A
-
K
D
P
---
R
I
A
A
T
M
E
N
A
Q
K
G
E
I
M
P
NIPQ
M
S
A
F
W
Y
A
V
R
T
A
V
--
I
------
N
A
A
S
G
R
-----
Q
T
V
D
A
A
-
L
A
A
A
---
Q
T
N
A
A
A
--
M
-
D
D
L
D
A
L
L
A
D
---
K
---------
P
F
S
G
L
D
C
L
W
C
R
----------
E
P
L
-------
T
E
V
D
A
F
R
C
M
V
K
D
F
H
V
V
-
I
R
E
--
G
C
R
Y
G
A
C
T
I
C
L
E
N
C
L
A
T
E
R
R
L
W
QGVP
V
T
G
E
E
A
---
E
L
L
H
G
KTLDRLCI
R
--------
C
C
YCGGKLT
K
N
E
K
-
H
----
R
H
V
L
F
N
E
P
F
C
K
T
R
A
N
I
I
R
G
R
C
YDCCRH
17
Fugue
36.12
20%
-48
- C10 -
-
1IUK
-
?
A:
[1-136]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
---
N
D
Q
E
L
R
A
Y
L
S
Q
A
K
T
I
A
-------
V
L
G
A
H
K
D
----
P
------
S
R
P
A
-
H
-----
Y
V
P
R
Y
L
-
R
E
Q
G
---
Y
R
V
L
P
V
N
P
R
-
F
Q
G
E
E
L
F
G
E
---
E
---------
A
V
A
S
L
L
D
L
K
E
P
----------
V
D
I
---
L
D
V
F
R
P
P
S
A
L
M
D
H
L
P
E
V
L
A
L
-
R
P
G
L
V
W
L
Q
S
G
I
R
H
P
E
F
E
K
A
L
K
E
A
G
I
P
-----
V
V
A
----------
D
--------
R
--------
C
L
-------
M
V
E
H
-
K
----
R
L
F
R
G
----------------------
4
HHSearch
33.11
21%
-470
- C10 -
-
1DI2
1
PRKAB_XENLA
A:
[2-15]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
V
G
S
L
Q
E
L
A
V
-
Q
K
G
W
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
31.69
10%
-149
- C9 -
-
1RKU
5
THRH_PSEAE
A:
[1-206]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
M
E
I
A
----
C
L
D
L
E
------
G
V
L
V
P
E
--
I
W
I
A
F
A
E
K
T
G
I
D
A
L
K
A
-----------
T
T
R
D
I
P
D
Y
D
V
L
M
K
Q
R
L
R
I
L
D
E
H
-----
G
L
K
L
G
D
I
-
Q
E
V
-
I
A
T
L
----------
K
P
L
E
G
A
V
E
F
V
D
W
L
R
E
R
F
-
Q
V
V
I
L
S
D
----
T
F
Y
E
F
S
Q
----
P
L
M
R
Q
L
-----
G
F
P
T
L
L
C
H
K
L
E
I
D
D
S
--
D
R
V
V
----------
G
Y
Q
L
R
Q
----
K
D
P
K
R
Q
S
--
V
I
A
--
F
K
-
S
L
Y
---
Y
R
V
I
A
A
G
D
S
Y
N
D
T
T
M
L
-------
S
E
A
H
A
G
I
L
F
HA
P
------
E
N
V
I
-
R
-----
E
F
P
Q
F
P
-
A
V
H
T
---
Y
E
D
L
K
R
--
E
-
F
L
K
A
S
S
R
S
L
---
S
---------
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
31.25
28%
-
- C10 -
-
4Z8Z
-
?
A:
[92-172]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
V
C
-------
N
I
L
L
L
H
G
L
Y
--
D
DNMLNY
G
F
L
T
-
R
-----
M
L
N
E
L
K
-
F
N
V
F
---
L
M
E
L
P
F
--
H
-
F
N
R
K
P
A
E
S
F
FSG
E
---------
Y
F
I
S
A
D
L
L
R
A
R
----------
N
A
F
---
I
Q
S
I
Y
D
I
E
A
S
R
N
L
--------------------------------------------------------------------------------------------------------------------
5
HHSearch
29.77
75%
-232
- C3 -
-
3H0D
-
CTSR_GEOSE
B:
[35-42]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
--------
C
V
-------
P
S
Q
I
-
N
-------------------------------
7
HHSearch
28.55
27%
-
- C1 -
-
5U5T
-
?
D:
[3-12]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
F
S
S
N
R
--
Q
K
I
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
27.96
75%
-150
- C4 -
-
3H0D
-
CTSR_GEOSE
A:
[35-42]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
--------
C
V
-------
P
S
Q
I
-
N
-------------------------------
3
PsiBlast_PDB
27.06
30%
-61
- C10 -
-
4R04
-
TOXA_CLODI
A:
[917-1024]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
--
I
F
-
S
-
K
---
Y
S
E
H
I
T
K
E
I
S
T
I
K
N
S
I
-------
I
T
D
V
N
G
--------------
Q
L
-
D
-----
H
T
S
Q
V
N
T
L
N
A
A
---
F
F
I
Q
S
L
--
I
D
Y
S
S
N
K
D
V
L
N
---
D
---------
L
S
T
S
V
K
V
Q
L
Y
A
----------
Q
L
F
STG
L
N
T
I
Y
D
S
I
Q
L
V
N
L
I
S
N
A
V
N
D
-
T
I
N
--
V
L
-----------------------------------------------------------------------------------------------------
13
HHSearch
23.86
22%
-208
- C11 -
-
3N40
-
?
F:
[42-95]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
L
---
S
L
D
Y
I
T
C
E
Y
K
T
V
I
P
S
P
-------
Y
V
K
C
C
G
T
A
E
--
C
--------
K
D
-
K
-----
N
L
P
D
Y
S
-
C
K
V
F
---
T
G
V
Y
P
F
--
M
-
W
G
G
A
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
21.01
28%
-82
- C7 -
-
3ZIF
-
CAPSH_ADEB3
A:
[618-704]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
P
P
N
A
T
Q
L
P
I
P
-
S
R
N
W
A
A
F
-
R
G
W
S
L
T
R
L
----------
K
-
Q
R
E
T
P
A
L
G
S
P
F
D
P
Y
F
T
Y
S
G
T
I
P
Y
----
L
D
G
T
F
Y
L
----
S
H
T
F
R
K
-----
V
A
I
Q
F
D
S
S
V
T
W
P
G
N
D
--
R
L
L
T
----------
P
N
E
F
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
20.24
20%
-146
* C11 *
-
3J0C
-
POLS_EEVV8
D:
[40-93]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
V
---
N
L
E
Y
V
T
C
H
Y
K
T
G
M
D
S
P
-------
A
I
K
C
C
G
S
Q
E
--
C
--------
T
P
-
T
-----
Y
R
P
D
E
Q
-
C
K
V
F
---
T
G
V
Y
P
F
--
M
-
W
G
G
A
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
19.92
19%
-
- C11 -
-
3J0F
-
?
G:
[40-93]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
S
T
---
N
Q
E
Y
I
T
C
K
F
T
T
V
V
P
S
P
-------
K
I
K
C
C
G
S
L
E
--
C
------
Q
--
P
-
A
-----
A
H
A
D
Y
T
-
C
K
V
F
---
G
G
V
Y
P
F
--
M
-
W
G
G
A
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
19.17
36%
-
- C2 -
-
2QXV
-
EZH2_MOUSE
B:
[40-50]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
M
F
S
S
N
R
--
Q
K
I
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
18.51
25%
-101
- C11 -
-
2YEW
-
?
K:
[40-104]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
S
L
---
V
Q
D
Y
I
T
C
N
Y
K
T
V
V
P
S
P
-------
Y
I
K
C
C
G
G
A
E
--
C
------
S
K
---------
N
E
A
D
Y
K
-
C
S
V
F
---
T
G
V
Y
P
F
--
M
-
W
G
G
A
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
18.37
20%
-106
* C10 *
-
2LO7
-
KA20_TITSE
A:
[1-31]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
G
C
M
K
E
Y
C
A
G
Q
C
R
-----
G
K
V
S
Q
D
---
Y
C
L
K
H
C-------
K
--------
C
I
-------
P
R
-----------------------------------
14
Fugue
17.64
35%
-74
- C5 -
-
4B2U
-
?
A:
[1-36]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
T
Y
-----
C
I
E
L
G
E
---
R
C
P
N
P
--------
R
EGDWCCHK
C
V
-------
P
E
G
--
K
----
R
F
Y
C
R
D
Q
--------------------
12
HHSearch
12.85
46%
54
- C10 -
-
3ADJ
-
DRB1_ARATH
A:
[101-113]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
C
K
N
L
L
Q
E
Y
A
Q
-
K
M
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------