@TOME V2.3
(Mar 2018)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0132: (2017-12-15 )
MHLTHREVRDKLLSYSEGLQVYYELYQLLLFHFQEKNADHFFGLIEQELPTVHPLFQTVFWTFLRDRDKIINALKLPYSNAKLEATNNLIKVIKRKAFGFRNFNNFKKRILMTLNIKKESTNFVLSRL
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10...--------.....---20------...-.....30---..-------......------------40....-------....50.....--...60--.........---70..------..-....80.....---...90.....-----.-..100--...-----.....--.110-------------------........120......---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHL
T
H
R
E
V
R
D
K
L
L
S
--------
Y
S
E
G
L
---
Q
V
------
Y
Y
E
-
L
Y
Q
L
L
L
F
---
H
F
-------QEKNA
D
------------
H
F
F
G
L
I
-------
E
Q
ELP
T
V
H
P
L
F
--
Q
T
V
F
---
W
T
F
L
R
D
R
D
K
---
I
I
N
A
------
L
K-LPYSNAKLE
A
T
---
N
N
L
I
K
V
I
K
R
K
-----A-FGF----R
N
F
-----
N
N
F
K
K
--
R
I
L
--------------------
M
T
L
N
IKKEST
N
F
V
LSRL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
75.75
21%
32
- C2 -
-
4D10
-
CSN8_HUMAN
H:
[14-212]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------F
S
F
K
K
L
L
D
Q
C
E
N
Q
E
L
E
--------
A
P
G
G
I
AT
P
P
V
------
Y
G
Q
-
L
L
A
L
Y
L
L
---
H
N
-------
D
M
N
N
A
R
------------
Y
L
W
K
R
I
P
P
A
I
K
S
A
N
S
E
L
G
G
I
W
S
V
G
--
Q
R
I
W
---
Q
R
D
F
P
G
I
Y
T
---
T
I
N
A
H
Q
W
S
ET
V
Q
-
P
I
M
E
A
L
R
D
A
T
R
---
R
R
A
F
A
L
V
S
Q
A
YTSII
A
-
D
D
F
----
A
A
F
V
GLP
V
E
E
A
V
K
--
G
I
L
--------------------
E
Q
G
W
Q
A
D
S
T
T
R
M
V
L
P
R
K
PEQ
Q
L
A
R
L
T
D
Y
V
A
F
L
E
N----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
Fugue
65.32
23%
21
- C2 -
-
4TQT
6
?
A:
[14-490]
------------------A
S
K
V
I
K
G
G
T
V
I
T
AD
R
T
F
R
A
D
I
L
I
E
DGKIAAIGD
S
L
E
G
D
E
V
I
D
ASG
C
Y
V
M
PG
G
I
D
P
H
T
H
L
QMPFMGTYSSDD
F
D
T
G
T
A
A
A
L
A
G
GTT
M
V
V
D
F
V
L
P
D
SEGN
L
L
D
A
L
Q
E
W
F
Q
K
A
G
KAR
T
D
Y
S
F
H
M
A
I
TGWN
E
R
T
F
N
E
M
A
E
V
V
K
R
GINTFHFMAYKG
A
L
M
V
N
D
D
E
M
F
A
S
F
Q
R
C
A
E
L
G
A
M
P
L
V
HAEN
G
D
I
V
A
Q
L
Q
A
K
L
M
A
E
GNDG
P
E
A
H
A
Y
S
R
P
P
E
V
E
G
E
A
T
N
R
A
I
M
I
A
D
Q
A
G
V
P
L
Y
V
V
HVSC
E
Q
S
H
E
A
I
R
R
A
R
Q
K
--------------
G
M
---
R
V
------
F
G
E
P
L
I
Q
H
L
T
L
DES
E
Y
-------
H
N
R
D
W
D
------------
Y
A
A
R
R
V
-------------
M
S
P
P
F
--
R
D
K
L
--------
N
Q
D
S
---
L
W
A
G
------
L
A
-
A
--
G
S
L
Q
C
V
A
T
---
D
H
C
A
F
T
T
E
Q
K
-----
R
-
Y
G
I
----
G
N
F
-----
T
K
I
P
N
---------------------------------
G
T
G
G
L
E
E
R
M
P
V
L
W
T
R
GVRTGRLT
P
N
E
F
V
A
V
T
S
T
N
I
A
K
I
L
NIYPQKGAVVPGADAD
L
V
I
W
D
PE
T
T
K
K
ISAKTQHSSIDYNVFEG
F
E
L
K
G
LPI
M
T
L
S
RGRIAFDKGQVTAKPGD
G
R
F
I
E
R
E
P
NG
A
V
N
R
A
L
S
Q
W
K
E
I
V
A
P
R
K
V
E
R
S
A------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
53.07
17%
102
- C5 -
-
5GOX
2
RAD50_HUMAN
A:
[5-185]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K
E
I
N
Q
T
R
D
R
L
A
K
L
N
K
E
L
A
S
S
E
Q
N
K
N
H
I
N
N
E
L
K
R
K
E
E
Q
L
S
S
--------
Y
E
D
K
L
---
F
D
V
CGSQD
F
E
S
-
D
L
D
R
L
K
E
---
E
I
-------
E
K
S
S
K
Q
R
A
M
L
A
G
A
T
A
V
Y
S
Q
F
I
T
Q
L
-------
T
D
E
N
Q
S
C
C
P
V
C
--
Q
R
V
F
QT
E
A
E
L
Q
E
V
I
S
D
---
L
Q
S
K
------
L
R
-
L
A
P
D
K
L
K
S
T
E
S
---
E
L
K
K
K
E
K
R
R
D
-----
E
M
L
G
L
V
P
M
R
Q
S
I
-----
I
D
L
K
E
--
K
E
I
--------------------
P
E
L
R
N
K
L
Q
N
V
N
R
D
I
Q
R
L
K--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
52.70
16%
46
- C1 -
-
2LIQ
1
?
A:
[1-153]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGHH
H
H
H
H
H
H
S
G
D
S
P
A
V
T
--------
L
S
A
G
------------
N
Y
I
-
I
Y
N
R
V
L
S
---
P
R
-------
G
E
K
L
A
L
------------
T
Y
P
G
R
--------
Q
R
T
P
V
T
V
S
P
L
D
GS
S
E
Q
A
---
W
I
L
R
S
Y
D
S
N
---
S
N
T
W
------
T
I
-
S
P
V
G
S
P
N
S
Q
I
G
W
GA
G
N
V
P
V
V
L
P
P
N
-----
N
-
Y
V
W
----
T
L
T
-----
L
T
S
G
G
--
Y
N
I
Q
D
GKRT
V
S
W
S
L
N
NATAG
E
E
V
S
I
G
A
D
A
T
F
S
G
R
W
V
I
E
K
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
50.14
18%
20
- C2 -
-
5N5X
-
RRN7_YEAST
B:
[94-514]
KLIGHEA
K
L
L
F
L
K
S
F
Q
F
I
L
K
R
Q
I
R
W
L
I
T
EMRFP
K
E
F
E
H
V
A
K
I
I
W
L
K
I
L
K
T
I
N
D
QPQEELKLQLH
M
T
S
T
I
S
I
L
Y
L
A
S
T
H
L
SLPVY
T
C
D
Y
I
K
W
I
C
T
AKMPYFQASEILRIQLP
N
Y
Y
V
S
I
L
E
GSISPFNG
Q
L
Y
N
K
I
A
L
T
C
G
M
I
HFKEFFNSEISC
Q
G
L
L
L
K
L
V
M
Q
C
ALPP
E
F
Y
F
Y
T
K
Q
V
I
E
F
E
ET
D
I
R
N
L
T
LWERTDERHTGRVSNH
A
E
L
R
V
L
S
Y
F
M
L
T
I
N
W
M
L
S
F
DRDRQYP
L
K
W
I
L
S
L
T
E
S
L
T
Q
R
T
T
T
S
E
S
I
G
R
N
I
V
K
V
V
Y
P
D
K
P
T
S
S
D
Y
F
Q
--------
W
S
E
E
E
---
T
L
------
E
F
L
-
K
W
M
E
K
Q
F
---
L
P
-------
T
Q
T
D
----------------
Q
K
I
A
-------
R
R
K
L
Y
K
I
F
P
L
D
--
S
T
H
Q
---
L
T
F
I
E
D
L
Q
E
---
R
Y
A
K
------
Q
T
-
P
F
F
P
P
A
R
K
E
A
I
---
G
R
L
L
T
H
I
A
S
Q
-----
L
-
L
V
D
--------------------------------------------
F
A
I
S
K
E
Q
L
K
D
C
I
S
R
I
K
N
A
C
L
H
R
M
N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
44.98
29%
40
- C4 -
-
1QWM
-
CATA_HELPY
A:
[454-490]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
V
T
H
K
E
I
V
D
K
Q
L
E
H
F
K
K
A
D
P
K
Y
A
E
G
V
---
K
K
------
A
L
E
-
K
H
Q
K
M
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
44.90
15%
-10
- C2 -
-
4QFH
2
?
A:
[6-615]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------H
H
H
M
K
D
Q
Y
L
K
D
L
T
V
H
L
N
E
SNAAPAN
T
S
M
A
V
A
S
F
N
M
P
H
E
I
T
R
R
M
RPLG
V
D
A
D
TSLTSC
P
S
W
R
R
L
Q
E
L
Y
E
I
HGSESIL
K
N
F
D
E
C
K
D
R
F
Q
R
Y
S
L
E
V
D
L
R
S
S
D
K
N
F
V
F
L
D
--------
Y
S
K
T
----
H
I
------
N
D
E
-
I
K
D
V
L
F
K
---
L
V
-------
E
E
R
G
I
R
------------
A
F
M
R
A
L
-------
F
A
G
E
K
V
N
T
A
E
N
--
R
S
V
L
---
H
I
A
L
R
N
R
S
N
R
P
I
F
V
N
G
------
H
D
V
M
P
L
V
N
K
V
L
E
Q
M
---
K
K
L
S
E
K
V
R
R
G
-----
E
-
W
K
G
----
Q
S
G
-----
K
P
I
R
H
--
V
V
N
--------------------
I
G
I
G
G
S
D
L
G
P
M
M
A
C
E
A
L
RPFSDRR
I
S
M
H
F
V
S
N
IDG
T
H
L
S
E
V
L
N
L
V
DLES
T
L
F
I
I
A
S
KTFTT
Q
E
T
I
T
N
A
L
S
A
R
N
E
F
L
K
F
L
S
S
R
GISEAG
A
V
A
K
H
F
V
A
L
STN
A
E
K
V
K
E
F
GIDEEN
M
F
Q
F
W
DWVGGRYSLWSAIG
L
S
V
M
I
S
IG
Y
D
N
F
V
E
L
L
T
G
A
H
I
M
D
E
H
F
I
N
APTENN
L
P
I
I
L
A
L
V
G
I
W
Y
N
NFFGSE
T
Q
A
I
L
P
YDQYLWR
L
P
A
Y
L
Q
Q
L
D
M
E
S
NGKGATKNGRMVSTHTG
P
I
I
F
G
E
A
G
T
N
G
Q
H
A
FYQLIHQGT
K
L
I
P
C
D
F
I
G
A
IQTQNYIGE
H
H
R
I
L
M
S
N
F
F
A
Q
T
E
A
L
M
IGKT
P
E
E
V
K
R
E
L
E
S
A
GGKS
E
D
E
I
Q
L
L
I
PQKTFTGG
R
P
S
N
S
L
L
V
KALT
P
R
A
L
G
A
I
I
A
M
Y
E
H
K
V
L
V
Q
G
A
I
W
GINSYDQWGV
E
L
G
K
L
L
A
K
S
I
L
L
Q
LQPG
Q
K
V
T
NHD
S
S
T
N
G
L
I
E
L
F
N
E
R
SH
26
HHSearch
44.89
17%
-206
- C4 -
-
3FXD
-
?
C:
[8-30]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Q
K
E
T
---
I
L
K
A
------
L
N
-
D
A
I
E
K
G
P
W
D
K
S
---
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
44.56
18%
-62
- C4 -
-
1YAR
-
?
S:
[13-88]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
-
L
I
Q
N
L
R
D
---
S
Y
-------
T
E
T
S
---------------
S
F
A
V
I
-------
E
E
W
A
A
G
T
L
Q
E
I
--
E
G
I
A
---
K
A
A
A
E
A
H
G
V
---
I
R
N
S
----------
T
Y
G
R
A
Q
A
E
K
S
---
P
E
Q
L
L
G
V
L
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
42.64
10%
36
* C5 *
-
3JB9
-
PRP19_SCHPO
S:
[1-132]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MF
C
S
I
S
G
E
T
P
K
E
P
V
I
S
--------
R
V
S
G
N
---
V
Y
------
E
K
R
-
L
I
E
Q
V
I
R
---
E
T
SKDPVTQ
Q
E
C
T
L
E
------------
D
L
V
P
V
K
-------
V
P
D
F
V
R
P
R
P
P
S
--
A
T
----------
S
L
P
A
---
L
L
S
L
------
F
Q
-
E
E
W
D
S
V
A
L
E
Q
F
---
E
L
R
R
N
L
T
E
T
K
-----
Q
-
E
L
S
----
T
A
L
-----
Y
S
L
D
A
AL
R
V
I
--------------------
S
R
L
T
K
E
R
D
E
A
R
E
A
L
A
K
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
40.93
32%
142
- C4 -
-
4MT4
-
?
A:
[414-470]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
L
E
A
R
Q
N
---
W
L
N
A
-------
A
-
V
A
F
N
N
I
K
Y
S
Y
A
---
N
S
I
V
D
V
I
--
K
-----
A
-
F
G
-------------
G
G
F
E
Q
--
S
E
D
--------------------
T
S
K
N
I
K
E
E
S
K
N
L
D
M
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
40.14
29%
37
- C4 -
-
1QWL
-
CATA_HELPY
A:
[454-491]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
V
T
H
K
E
I
V
D
K
Q
L
E
H
F
K
K
A
D
P
K
Y
A
E
G
V
---
K
K
------
A
L
E
-
K
H
Q
K
M
M
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
39.23
29%
27
- C4 -
-
2A9E
-
CATA_HELPY
A:
[458-491]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
V
T
H
K
E
I
V
D
K
Q
L
E
H
F
K
K
A
D
P
K
Y
A
E
G
V
---
K
K
------
A
L
E
-
K
H
Q
K
M
M
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
38.97
29%
24
- C4 -
-
2IQF
-
CATA_HELPY
A:
[458-491]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
V
T
H
K
E
I
V
D
K
Q
L
E
H
F
K
K
A
D
P
K
Y
A
E
G
V
---
K
K
------
A
L
E
-
K
H
Q
K
M
M
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
38.83
24%
-72
- C3 -
-
1JNU
1
?
A:
[61-104]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
R
D
V
T
V
Q
V
L
N
--------
Y
T
K
G
G
---
R
A
------
F
W
N
-
L
F
H
L
Q
V
M
---
R
D
-------
E
N
G
D
V
Q
------------
Y
F
I
G
-
V
-------
Q
Q
E
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
36.82
24%
-47
* C3 *
-
1G28
1
?
A:
[61-104]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
R
D
V
T
V
Q
V
L
N
--------
Y
T
K
G
G
---
R
A
------
F
W
N
-
L
F
H
L
Q
V
M
---
R
D
-------
E
N
G
D
V
Q
------------
Y
F
I
G
-
V
-------
Q
Q
E
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
36.78
33%
-58
- C4 -
-
4X7V
1
MYCF_MICGR
A:
[23-55]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
S
T
G
V
---
E
L
------
Y
L
D
-
L
L
K
R
T
V
S
---
N
F
-------
I
Y
Q
D
A
T
------------
H
V
A
G
L
I
-------
T
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
36.78
40%
77
- C4 -
-
5GJQ
-
PSMD3_HUMAN
S:
[295-326]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
A
------
I
Q
-
L
E
Y
S
E
A
R
R
T
M
T
---
N
A
L
R
K
A
P
Q
H
T
-----
A
-
V
G
F
----
K
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
36.59
40%
33
- C4 -
-
5L4K
-
PSMD3_HUMAN
S:
[295-326]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
A
------
I
Q
-
L
E
Y
S
E
A
R
R
T
M
T
---
N
A
L
R
K
A
P
Q
H
T
-----
A
-
V
G
F
----
K
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
36.39
40%
-
- C4 -
-
5T0I
-
PSMD3_HUMAN
V:
[295-326]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
A
------
I
Q
-
L
E
Y
S
E
A
R
R
T
M
T
---
N
A
L
R
K
A
P
Q
H
T
-----
A
-
V
G
F
----
K
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------