@TOME V2.3
(Mar 2018)
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0766: (2017-12-29 )
MSRVRVQIMNQFHRKSHEYKAIKRYWKLIQQDSRKLSDKRFYRPTFRMHLTNKEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPEKFFGLIEDNLKQVHPIFQTVFKTFLKNKEKIVNALQLPYSNAKIGSDQ
Atome Classification :
(20 SA)
--------------------------------------------------------------.........10---.........------------20....----....30.--.....---..------------40---..-....--...50------.-------------........---60..-......70........80-------------..-......90........100.------.--.....110...--....120-.........130..-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
--------------------------------------------------------------MSR
V
R
V
Q
I
M
N
----
Q
F
H
RKS
H
E
Y
------------
K
A
I
K
R
Y
----
W
K
L
I
Q
Q
D
--
S
R
KLS---DK------------R----FY-R
P
T
F
--
R
M
HL-------T-------------
N
K
E
I
L
D
K
I
---
L
S
Y
S
-
E
D
L
K
H
H
Y
Q
I
Y
Q
L
L
L
F
H
FQ-------------NK-
D
P
E
K
F
F
G
L
I
E
D
N
L
K
Q
V
H
P
I
F
------
Q
--
T
V
F
K
T
F
LK
N
K
E
--
K
I
V
N
A
---
L
QLPYSNAKIGSDQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
72.51
17%
-42
- C4 -
-
2MN2
-
?
A:
[1-122]
----------------------------------------------------------------------
M
D
----
E
Y
S
P
K
R
H
D
V
------------
A
Q
L
K
F
L
----
C
E
S
L
Y
D
E
--
G
I
A
T
L
---
G
D
------------
S
HHGW
V
N
-
D
P
T
S
--
A
V
N
L
-------
Q
-------------
L
N
D
L
I
E
H
I
---
A
S
F
V
-
M
S
F
K
I
K
Y
-------------------------
P
-
D
D
G
D
L
S
E
L
V
E
E
Y
L
D
D
T
Y
T
L
F
SSYGIN
D
--
P
E
L
Q
R
W
Q
K
T
K
E
--
R
L
F
R
L
---
F
S
G
E
Y
I
S
T
L
M
K
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
71.18
27%
-
- C5 -
-
4H63
-
MED18_SCHPO
R:
[89-157]
----------------------------------------------------------------------------------------------------------------------
K
R
E
---
D
K
------------
C
----
G
I
-
R
P
V
N
--
R
A
K
L
-------
T
-------------
N
G
S
V
T
E
F
V
---
E
K
M
G
-
Y
E
F
S
H
E
Y
-
I
I
Q
G
L
E
Y
F
F
F
-------------
D
T
-
T
V
R
I
Y
Q
T
L
I
P
S
Q
Q
R
S
I
K
P
P
F
------
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
62.52
19%
-8
- C4 -
-
5HJQ
1
?
A:
[78-367]
-------------------------------ALRS
Y
T
E
I
Q
Q
L
L
Q
Q
GK
K
R
D
V
K
N
I
L
R
E
NSWPI
N
S
P
I
R
A
Q
L
W
P
----
M
L
C
G
Q
H
L
D
----------------
G
F
Y
----
W
E
M
V
H
Q
V
FG
T
T
E
L
S
---
E
K
------------
P
----
I
M
-
L
P
A
F
VD
A
T
H
C
LPYHLT
S
T
-------------
G
R
A
V
A
D
R
I
V
N
V
L
G
Y
D
C
P
D
I
T
Y
S
P
V
L
Y
P
I
T
S
I
L
L
H
-------------
F
M
-
S
E
E
E
A
Y
I
C
L
A
G
L
V
G
S
K
E
K
V
F
----------
I
N
Q
T
K
L
Q
H
E
V
--
T
W
K
T
V
---
M
Q
I
A
K
K
H
T
K
S
A
T
S
Y
F
Q
R
I
C
PGLKLERIFMD
W
C
W
W
I
L
AGLP
F
Q
H
L
V
R
I
M
D
C
Y
F
H
EGI
K
V
L
Y
R
V
A
L
V
I
L
N
L
F
H
K
E
C
Q
SNNEWSPDNIKND
I
G
N
A
L
I
K
F
C
K
K
IPVS
P
A
K
L
L
H
A
A
F
S
IRGLS
T
Q
Y
I
S
R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
61.31
15%
-
- C4 -
-
5DSE
-
TTC7B_HUMAN
A:
[140-843]
V
I
A
E
A
Y
A
T
K
G
L
C
L
ED
V
I
T
C
Y
E
K
A
G
D
I
A
L
L
Y
L
Q
E
I
E
R
VLG
F
F
L
E
T
G
L
Q
R
A
H
V
L
Y
F
K
N
GN
L
T
R
G
V
G
R
F
R
-
E
L
L
R
----
A
V
E
T
R
T
T
Q
N
------------
L
R
M
T
I
A
----
R
Q
L
A
E
I
L
--
L
R
G
M
C
---
E
Q
------------
S
----
Y
W
-
N
P
L
E
--
D
P
F
C
PQ-----
E
-------------
N
T
E
E
A
L
L
L
---
L
L
I
S
-
E
S
M
A
N
R
S
V
V
Y
D
L
L
T
I
A
L
G
-------------
R
R
G
Q
Y
E
M
L
S
E
C
L
E
R
A
M
K
F
A
F
E
E
F
------
H
--
L
W
Y
Q
F
A
L
S
L
M
A
A
G
K
S
A
R
A
---
V
K
V
L
K
E
C
I
R
L
K
P
D
D
A
T
I
P
L
L
A
A
K
L
C
M
G
SLHW
L
E
E
A
E
K
F
A
K
T
V
VT
S
E
F
K
A
K
G
Y
L
A
L
G
L
T
Y
S
L
Q
A
T
D
ASL
R
G
M
Q
E
V
L
Q
R
K
A
L
L
A
F
Q
R
A
H
S
L
SPTD
H
Q
A
A
F
Y
L
A
L
Q
L
A
I
S
RQ
I
P
E
A
L
G
Y
V
R
Q
A
L
Q
L
QGDD
A
N
S
L
H
L
L
A
L
L
L
S
A
Q
KH
Y
H
D
A
L
N
I
I
D
M
A
L
S
E
Y
PEN
F
I
L
L
F
S
K
V
K
L
Q
S
L
CRG
P
D
E
A
L
L
T
C
K
H
M
L
Q
I
W
K
S
C
YLHP
W
M
T
L
A
Q
I
W
L
H
A
A
E
V
Y
I
G
I
GK
P
A
E
A
T
A
C
T
Q
E
A
A
N
L
FPMS
H
N
V
L
Y
M
R
G
Q
I
A
E
L
R
GS
M
D
E
A
R
R
W
Y
E
E
A
L
A
I
SPTH
V
K
S
M
Q
R
L
A
L
I
L
H
Q
L
GR
Y
S
L
A
E
K
I
L
R
D
A
V
Q
V
NSTA
H
E
V
W
N
G
L
G
E
V
L
Q
A
Q
GN
D
A
A
A
T
E
C
F
L
T
A
L
E
L
E
A
S
SPAVPFTIIPRVL
15
PsiBlast_PDB
54.58
26%
-79
- C4 -
-
2D2R
-
ISPT_HELPY
A:
[74-136]
-------------------------------------------------------------------------------------------------
K
M
L
K
K
Y
----
L
K
--
D
E
R
--
S
T
Y
L
D
---
N
N
------------
I
----
R
F
-
R
A
I
G
--
D
L
E
G
-------
F
-------------
S
K
E
L
R
D
T
I
---
L
Q
L
E
-
N
D
T
R
H
F
K
D
F
T
Q
V
L
A
L
N
Y
G
-------------
S
K
-
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
52.91
26%
-91
- C4 -
-
2DTN
-
ISPT_HELPY
A:
[85-147]
-------------------------------------------------------------------------------------------------
K
M
L
K
K
Y
----
L
K
--
D
E
R
--
S
T
Y
L
D
---
N
N
------------
I
----
R
F
-
R
A
I
G
--
D
L
E
G
-------
F
-------------
S
K
E
L
R
D
T
I
---
L
Q
L
E
-
N
D
T
R
H
F
K
D
F
T
Q
V
L
A
L
N
Y
G
-------------
S
K
-
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
52.49
27%
-89
- C5 -
-
3C0T
-
MED18_SCHPO
A:
[89-157]
----------------------------------------------------------------------------------------------------------------------
K
R
E
---
D
K
------------
C
----
G
I
-
R
P
V
N
--
R
A
K
L
-------
T
-------------
N
G
S
V
T
E
F
V
---
E
K
M
G
-
Y
E
F
S
H
E
Y
-
I
I
Q
G
L
E
Y
F
F
F
-------------
D
T
-
T
V
R
I
Y
Q
T
L
I
P
S
Q
Q
R
S
I
K
P
P
F
------
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
51.35
27%
-91
* C5 *
-
5U0S
-
MED18_SCHPO
R:
[89-157]
----------------------------------------------------------------------------------------------------------------------
K
R
E
---
D
K
------------
C
----
G
I
-
R
P
V
N
--
R
A
K
L
-------
T
-------------
N
G
S
V
T
E
F
V
---
E
K
M
G
-
Y
E
F
S
H
E
Y
-
I
I
Q
G
L
E
Y
F
F
F
-------------
D
T
-
T
V
R
I
Y
Q
T
L
I
P
S
Q
Q
R
S
I
K
P
P
F
------
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
50.51
27%
-76
- C5 -
-
5U0P
-
MED18_SCHPO
R:
[89-157]
----------------------------------------------------------------------------------------------------------------------
K
R
E
---
D
K
------------
C
----
G
I
-
R
P
V
N
--
R
A
K
L
-------
T
-------------
N
G
S
V
T
E
F
V
---
E
K
M
G
-
Y
E
F
S
H
E
Y
-
I
I
Q
G
L
E
Y
F
F
F
-------------
D
T
-
T
V
R
I
Y
Q
T
L
I
P
S
Q
Q
R
S
I
K
P
P
F
------
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
49.54
15%
20
- C4 -
-
1UG7
-
AIDA_MOUSE
A:
[1-128]
-------------------------------------------------------GSSGSSG
M
S
E
V
T
R
S
L
L
Q
----
R
W
G
A
S
L
R
R
G
------------
A
D
F
D
S
W
----
G
Q
L
V
E
A
I
--
D
E
Y
Q
I
---
L
A
------------
R
----
H
L
-
Q
K
E
A
--
Q
A
Q
H
-------
N
-------------
N
S
E
F
T
E
E
Q
---
K
K
T
I
-
G
K
I
A
T
C
L
E
L
R
S
A
A
L
Q
S
T
Q
-------------
S
Q
-
E
E
F
K
L
-----
E
D
L
K
K
L
E
P
I
L
------
K
--
N
I
L
-
T
Y
N
K
E
F
P
--
F
D
V
Q
P
---
I
S
G
P
S
S
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
48.94
27%
-56
- C5 -
-
5N9J
-
MED18_SCHPO
X:
[92-160]
----------------------------------------------------------------------------------------------------------------------
K
R
E
---
D
K
------------
C
----
G
I
-
R
P
V
N
--
R
A
K
L
-------
T
-------------
N
G
S
V
T
E
F
V
---
E
K
M
G
-
Y
E
F
S
H
E
Y
-
I
I
Q
G
L
E
Y
F
F
F
-------------
D
T
-
T
V
R
I
Y
Q
T
L
I
P
S
Q
Q
R
S
I
K
P
P
F
------
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
47.96
27%
-29
- C4 -
-
2B5D
-
?
X:
[51-128]
-----------------------------------------------------------------------------------------------------------------------------------------------------
F
--
R
L
T
M
-------
S
-------------
I
T
P
P
L
M
E
M
---
L
S
-
S
-
R
D
L
Q
E
K
Y
E
R
H
M
E
K
L
I
E
L
A
-------------
N
K
-
E
V
E
R
--------
T
K
K
E
H
P
L
K
------
H
--
K
M
A
K
F
Y
R
E
H
F
E
--
K
I
L
N
V
---
F
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
47.77
16%
85
- C2 -
-
4MT5
-
?
A:
[0-183]
--------------------------------------------------------------
M
Q
T
A
Y
V
K
Y
V
D
DTTG
E
T
L
R
Q
D
D
L
H
G
Y
TDETIPYST
A
E
G
I
K
K
Y
E
G
D
G
Y
V
L
V
S
D
G
--
F
K
P
G
T
---
K
F
------------
G
----
V
G
-
T
P
T
Y
--
E
V
H
F
-------
K
H
G
M
T
H
T
D
ATDKN
A
E
Q
K
T
V
T
E
T
---
I
H
Y
V
-
D
E
N
N
Q
T
V
Q
P
D
S
T
T
A
V
T
F
K
R
G
Y
T
T
D
NVTGKVV
S
Y
-
D
P
W
T
V
D
G
N
Q
A
D
S
-
K
T
F
A
A
V
P
------
S
--
P
A
V
E
G
Y
T
P
N
H
Q
--
Q
I
-
N
E
---
F
T
V
T
P
D
S
K
D
I
V
K
T
V
V
Y
V
G
DP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
45.95
26%
-60
- C4 -
-
3F3S
3
CRYL1_HUMAN
A:
[196-263]
-----------------------------------------------------------------------------------
Q
Y
------------
A
I
I
S
E
A
----
W
R
L
V
E
E
G
--
I
V
S
P
S
---
D
L
D
L
V
M
S
E
G
L
G
M
R
Y
A
----
F
I
-
G
P
L
E
--
T
M
H
L
-------
N
-------------
A
E
G
M
L
S
Y
C
---
D
R
Y
S
-
E
G
I
K
H
V
L
Q
T
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
45.47
41%
-28
- C4 -
-
4MYC
-
ATM1_YEAST
A:
[383-429]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
Q
-------------
L
S
-
V
P
L
N
F
L
G
S
V
Y
R
D
L
K
Q
S
L
I
D
M
------
E
--
T
L
F
K
-
L
R
K
N
E
V
--
K
I
K
N
A
ERP
L
M
L
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
45.09
25%
-148
- C3 -
-
4UUY
-
PEP3_YEAST
A:
[269-343]
-----------------------------------------------------------------------------------------------------------------------------------------------------
F
--
H
I
L
L
-------
L
-------------
R
K
N
T
V
T
M
V
---
S
Q
L
N
-
N
D
V
V
F
H
E
T
I
---------------------------
E
K
F
L
G
L
V
R
D
S
V
K
E
T
F
W
C
F
------
S
NI
N
V
F
E
I
I
I
E
N
E
P
--
N
S
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
44.05
41%
-20
- C4 -
-
4MYH
-
ATM1_YEAST
A:
[286-332]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
Q
-------------
L
S
-
V
P
L
N
F
L
G
S
V
Y
R
D
L
K
Q
S
L
I
D
M
------
E
--
T
L
F
K
-
L
R
K
N
E
V
--
K
I
K
N
A
E
RP
L
M
L
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
43.59
15%
-149
- C4 -
-
1QCK
-
BAF_HUMAN
B:
[37-84]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
G
F
D
K
A
Y
V
V
L
G
Q
F
L
V
L
K
---------------
K
-
D
E
D
L
F
R
E
W
L
K
D
T
C
G
A
N
A
K
Q
S
------
R
--
D
C
F
G
C
L
R
E
W
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
43.28
26%
-22
- C4 -
-
4MIV
1
SPHM_HUMAN
A:
[384-454]
-----------------------------------------------------------------------------------------------------
R
H
----
F
R
L
V
H
N
L
--
N
F
K
M
P
F
P
I
D
Q
------------
D
----
F
Y
V
S
P
T
F
--
Q
-
D
L
-------
L
-------------
N
R
T
T
A
G
Q
P
---
T
G
W
Y
-
K
D
L
R
H
Y
Y
Y
R
A
R
W
E
L
Y
D
-
R
-------------
S
R
-
D
P
H
E
T
Q
N
L
A
T
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
41.93
22%
-277
- C4 -
-
2DII
-
A:
[17-34]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
K
N
R
M
---
L
Q
E
D
-
P
V
L
F
Q
L
Y
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------