@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0860: (2017-12-31 )
MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSVSLERELETRLVDRERVINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLLKEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLEFPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAMSSLGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKMQDVLFPSLLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPFTYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIERWGSSRKKEVFKV
Atome Classification :
(20 SA)
.........10........20........30........40......-..50-........----.60----........70........80.....--...90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200........-210........220.-......230.......240.......250.......260.......270.......280.......290.......300.......310-----.-.-----.-----....320.-.-.-.....330.......340-.--..--....------------------.--------------------------350.-----------------......360.......370.......380.......390.
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MK
D
V
S
L
F
L
L
K
K
V
F
K
S
R
L
N
W
I
I
L
L
L
F
A
S
V
LG
V
T
F
Y
LNSQTAN
S
V
S
L
E
R
-
E
L
E
--
T
R
L
V
D
R
E
R
----VIN----E
N
E
E
K
L
S
Q
MSDTSS
E
E
Y
Q
F
AKNNL
D
--
V
Q
K
N
L
L
T
R
K
T
E
I
L
T
L
L
KEGRWK
E
A
Y
Y
L
Q
WQDEEK
N
Y
E
F
VSNDPTASSGLKMGV
D
R
E
R
K
I
Y
Q
A
LYPL
N
I
K
A
H
T
L
EFPTH
G
I
D
Q
I
V
W
I
L
E
V
I
I
P
S
L
F
V
V
A
I
I
F
M
L
T
Q
L
F
A
E
R
Y
Q
N
H-LDTAHLYP
V
-
S
K
-
V
T
F
A
M
S
S
LG
V
G
V
-
G
Y
V
T
V
L
F
I
G
I
C
G
F
S
F
L
V
G
S
L
I
S
G
FGQLDYPY
P
I
Y
S
L
VNQEVTI
G
K
M
Q
D
V
L
F
P
S
L
L
L
A
F
L
A
F
I
V
I
V
E
V
V
Y
L
I
A
Y
F
F
K
QK
M
P
V
L
F
L
S
L
I
G
I
-----
V
-
G
-----
L
-----
L
F
G
I
Q
-
T
I
-
Q
-
P
-
L
Q
R
I
A
H
L
I
P
F
T
Y
L
R
S
V
E
--
I
--
L
S
--
G
R
L
S
------------------
K
--------------------------QID
N
-----------------
V
DLNWS
M
G
M
V
L
L
P
C
L
I
I
L
L
L
V
G
I
L
F
I
E
R
WGSSR
K
K
EVFKV
9
PsiBlast_PDB
86.81
26%
-
- C3 -
-
1EI3
-
FIBB_CHICK
B:
[86-187]
------------------------------------------------
E
L
Q
--
T
T
L
L
K
Q
E
K
T
V
K
P
V
L
R
----
D
L
K
D
R
V
A
K
F
S
D
T
S
T
T
M
Y
Q
Y
V
-
N
M
I
D
N
K
L
V
K
T
Q
K
Q
R
K
D
N
D
I
I
L
S
E
Y
N
T
E
M
E
L
H
Y
N
Y
I
K
D
N
L
D
N
-----
N
I
P
S
S
L
R
V
L
R
A
V
I
D
S
L
H
K
K
I
Q
K
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
69.06
16%
-
- C3 -
-
4RFX
-
DCTN1_CHICK
A:
[432-531]
--------------------------------------------
M
V
E
-
T
L
T
--
E
R
N
L
D
L
E
E
----
K
V
R
----
E
L
R
E
T
V
G
D
L
E
A
M
N
E
M
N
D
E
L
Q
E
N
A
R
E
--
T
E
L
E
L
R
E
Q
L
D
L
A
A
A
R
V
R
E
---
A
E
K
R
V
E
A
A
Q
E
T
V
A
D
Y
Q
Q
T
I
K
K
Y
R
E
L
T
A
H
L
Q
D
V
N
R
E
L
M
S
Q
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
61.79
26%
23
- C3 -
-
1M1J
-
FIBB_CHICK
B:
[86-187]
------------------------------------------------
E
L
Q
--
T
T
L
L
K
Q
E
K
T
V
K
P
V
L
R
----
D
L
K
D
R
V
A
K
F
S
D
T
S
T
T
M
Y
Q
Y
V
-
N
M
I
D
N
K
L
V
K
T
Q
K
Q
R
K
D
N
D
I
I
L
S
E
Y
N
T
E
M
E
L
H
Y
N
Y
I
K
D
N
L
D
N
-----
N
I
P
S
S
L
R
V
L
R
A
V
I
D
S
L
H
K
K
I
Q
K
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
59.08
13%
-159
- C3 -
-
5NJ3
1
?
A:
[451-663]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
A
V
E
L
F
V
V
E
K
K
L
F
I
H
E
Y
I
S
G
Y
-
Y
R
V
S
S
Y
F
L
G
K
L
L
S
D
L
L
P
M
R
M
L
P
S
I
I
F
T
C
I
V
Y
----
F
M
L
G
L
K
---
P
K
-----
A
-----------
D
A
F
F
V
M
M
F
T
L
M
M
V
A
Y
S
A
S
S
M
A
L
A
I
A
A
G
Q
S
V
V
S
V
A
T
L
L
M
T
I
C
F
-----
V
-
F
-----
M
M
I
F
SG
L
L
V
N
L
T
T
I
A
S
-
W
-
L
S
W
L
Q
Y
F
S
I
P
R
Y
G
F
T
A
L
--
Q
H
N
E
F
--
L
G
Q
N
------------------
F
CPGLNATGNNPCNYATCT
G
E
E
Y
L
V
K
Q
G
I
D
L
-----------------
S
P
W
G
L
W
K
N
H
V
A
L
A
C
M
I
V
I
F
L
T
I
A
Y
L
K
L
L
F
L
K
K
Y
-------
17
HHSearch
58.73
13%
-159
- C3 -
-
5NJG
1
?
B:
[451-663]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
A
V
E
L
F
V
V
E
K
K
L
F
I
H
E
Y
I
S
G
Y
-
Y
R
V
S
S
Y
F
L
G
K
L
L
S
D
L
L
P
M
R
M
L
P
S
I
I
F
T
C
I
V
Y
----
F
M
L
G
L
K
---
P
K
-----
A
-----------
D
A
F
F
V
M
M
F
T
L
M
M
V
A
Y
S
A
S
S
M
A
L
A
I
A
A
G
Q
S
V
V
S
V
A
T
L
L
M
T
I
C
F
-----
V
-
F
-----
M
MIFSG
L
L
V
N
L
T
T
I
A
S
-
W
-
L
S
W
L
Q
Y
F
S
I
P
R
Y
G
F
T
A
L
--
Q
HN
E
F
--
L
G
Q
N
------------------
F
CPGLNATGNNPCNYATCTGEEYLVKQ
G
I
D
L
-----------------
S
P
W
G
L
W
K
N
H
V
A
L
A
C
M
I
V
I
F
L
T
I
A
Y
L
K
L
L
F
L
K
K
Y
-------
5
PsiBlast_PDB
56.21
25%
-6
- C3 -
-
5I6I
-
?
A:
[849-991]
------------------------------
L
N
L
Y
L
D
G
Q
K
A
R
E
L
N
L
I
A
-
D
L
L
--
S
M
Y
A
D
V
E
C
----
Q
F
S
GRRL
Q
D
E
E
A
I
L
K
L
R
D
Q
Y
K
D
N
I
Q
K
V
V
N
T
V
L
--
S
H
K
N
V
M
S
K
N
S
L
V
L
A
L
L
D
E
Y
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
54.45
25%
16
- C3 -
-
5I6H
-
?
A:
[125-262]
------------------------------
L
N
L
Y
L
D
G
Q
K
A
R
E
L
N
L
I
A
-
D
L
L
--
S
M
Y
A
D
V
E
C
----
Q
F
S
GRRL
Q
D
E
E
A
I
L
K
L
R
D
Q
Y
K
D
N
I
Q
K
V
V
N
T
V
L
--
S
H
K
N
V
M
S
K
N
S
L
V
L
A
L
L
D
E
Y
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
53.70
27%
210
- C3 -
-
2P22
-
SRN2_YEAST
C:
[121-191]
------------------------------------
S
K
K
Y
G
D
I
A
L
K
K
-
K
L
E
Q
N
T
K
K
L
D
E
E
-------
S
----
S
Q
L
E
T
T
T
R
S
I
D
S
A
D
D
L
D
Q
F
I
K
N
Y
L
D
--
I
R
T
Q
Y
H
L
R
R
E
K
L
A
T
W
D
K
Q
G
N
L
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
52.35
15%
82
- C3 -
-
5D3A
1
KI21A_HUMAN
A:
[1-82]
--------------------------------------------
G
S
M
-
T
I
S
--
N
M
E
A
D
M
N
R
----
L
L
K
----
Q
R
E
E
L
T
K
R
R
E
K
L
S
K
R
R
E
K
I
V
K
E
N
G
E
--
G
D
K
N
V
A
N
I
N
E
E
M
E
S
L
T
A
N
I
D
Y
I
N
D
S
I
S
D
C
Q
A
N
I
M
Q
M
E
E
A
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
51.10
18%
-41
- C- -
-
1X8Y
-
LMNA_HUMAN
A:
[313-386]
----------------------------------
L
A
A
K
E
A
K
L
R
D
L
E
D
-
S
L
A
--
R
E
R
D
T
S
R
R
----
L
L
A
----
E
K
E
R
E
M
A
E
M
R
A
R
M
Q
Q
Q
L
D
E
Y
Q
E
L
L
D
--
I
K
L
A
L
D
M
E
I
H
A
Y
R
K
L
L
E
G
E
E
E
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
48.05
15%
35
- C3 -
-
3QH9
1
A:
[14-79]
----------------------------------------------------------
Q
E
E
----
K
Q
R
----
K
A
E
E
L
L
Q
E
L
R
H
L
K
I
K
V
E
E
L
E
N
E
R
N
Q
--
Y
E
W
K
L
K
A
T
K
A
E
V
A
Q
L
Q
E
Q
V
A
L
K
D
A
E
I
E
R
L
H
S
Q
L
S
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
47.60
34%
-
- C3 -
-
4N06
-
CAS1A_ARCFU
A:
[189-231]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
N
G
R
R
G
I
E
--
I
--
G
S
--
P
R
Y
A
------------------
K
--------------------------
D
I
V
N
-----------------
A
M
L
N
Y
G
Y
S
I
L
L
A
E
C
V
K
A
V
E
L
A
G
L
-----------------
12
HHSearch
46.83
7%
-158
- C3 -
-
5DO7
-
ABCG5_HUMAN
A:
[444-650]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
R
A
V
S
D
Q
E
S
Q
D
G
L
Y
-
Q
K
-
W
Q
M
M
L
A
Y
A
L
H
V
L
-
P
F
S
V
V
A
T
M
I
F
S
S
V
C
Y
----
W
T
L
G
L
H
---
P
E
-----
V
-----------
A
R
F
G
Y
F
S
A
A
L
L
A
P
H
L
I
G
E
F
L
T
L
V
L
L
G
I
V
Q
N
P
N
I
V
N
S
V
V
A
L
L
S
I
A
G
V
L
V
G
S
-----
G
-----
F
L
R
N
I
Q
E
M
-
P
-
I
P
F
K
I
I
S
Y
F
T
F
Q
K
Y
C
S
E
I
L
--
V
--
V
N
E
F
Y
G
L
N
------------------
F
--------------------------
T
C
--AFTQ
G
I
Q
F
I
E
K
TCPG--
A
T
S
R
F
T
M
N
F
L
I
L
Y
S
F
I
P
A
L
V
I
L
G
I
V
V
F
K
I
R
D
H
L
I
S
-----
25
Fugue
46.78
25%
-53
- C3 -
-
3EFG
1
SLYX_XANCP
A:
[8-58]
--------------------------------------------
R
D
Q
-
E
L
E
--
A
R
L
V
E
L
E
T
----
R
L
S
----
F
Q
E
Q
A
L
T
E
L
S
E
A
L
A
D
A
R
L
T
G
A
R
N
A
E
--
L
I
R
H
L
L
E
D
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
46.02
9%
-135
- C3 -
-
5DO7
-
ABCG8_HUMAN
B:
[480-674]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Y
Y
E
L
E
D
G
L
Y
T
T
-
G
P
Y
F
F
A
K
I
L
G
E
L
-
P
E
H
C
A
Y
I
I
I
Y
G
M
P
T
Y
W
----
L
A
N
L
R
---
P
G
-----
L
-----------
Q
P
F
L
L
H
F
L
L
V
W
L
V
V
F
C
C
R
I
M
A
L
A
A
A
A
L
L
P
T
F
H
M
A
S
F
F
S
N
A
L
Y
-----
N
-
S
F
Y
L
A
G
G
-----
F
M
I
N
L
S
S
L
-
W
T
V
-
P
A
W
I
S
K
V
S
F
L
R
W
C
F
E
G
L
M
K
I
--
Q
F
--
S
R
R
T
Y
K
M
P
L
G
NLTIAVSGD
K
I
L
S
--------------------------
V
M
E
L
-----------------
D
S
Y
P
L
Y
A
I
Y
L
I
V
I
G
L
S
G
G
F
M
V
L
Y
Y
V
S
L
R
F
I
K
Q
K
P
S
Q
D
---
11
HHSearch
45.68
7%
-167
- C3 -
-
5DO7
-
ABCG5_HUMAN
C:
[444-649]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
R
A
V
S
D
Q
E
S
Q
D
G
L
Y
-
Q
K
-
W
Q
M
M
L
A
Y
A
L
H
V
L
-
P
F
S
V
V
A
T
M
I
F
S
S
V
C
Y
----
W
T
L
G
L
H
---
P
E
-----
V
-----------
A
R
F
G
Y
F
S
A
A
L
L
A
P
H
L
I
G
E
F
L
T
L
V
L
L
G
I
V
Q
N
P
N
I
V
N
S
V
V
A
L
L
S
I
A
G
V
L
V
G
S
-----
G
-----
F
L
R
N
I
Q
E
M
-
P
-
I
P
F
K
I
I
S
Y
F
T
F
Q
K
Y
C
S
E
I
L
--
V
--
V
N
E
F
Y
G
L
N
------------------
F
--------------------------
T
C
G
S
MCAFTQ
G
I
Q
F
I
E
K
TCPG
A
T
S
R
F
T
M
N
F
L
I
L
Y
S
F
I
P
A
L
V
I
L
G
I
V
V
F
K
I
R
D
H
L
I
------
3
PsiBlast_PDB
45.29
27%
180
- C3 -
-
2F66
-
SRN2_YEAST
C:
[11-75]
------------------------------------
S
K
K
Y
G
D
I
A
L
K
K
-
K
L
E
Q
N
T
K
K
L
D
E
E
-------
S
----
S
Q
L
E
T
T
T
R
S
I
D
S
A
D
D
L
D
Q
F
I
K
N
Y
L
D
--
I
R
T
Q
Y
H
L
R
R
E
K
L
A
T
W
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
44.64
24%
157
- C3 -
-
5I7C
-
CNN_DROME
A:
[4-62]
-------------------------------------
H
D
C
A
K
V
D
L
E
N
A
E
L
R
--
R
K
L
I
R
T
K
R
----
A
F
E
----
D
T
Y
E
K
L
R
M
A
N
K
A
K
A
Q
V
E
K
D
I
K
N
Q
I
L
--
K
T
H
N
V
L
R
N
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
44.58
27%
237
- C3 -
-
2CAZ
-
SRN2_YEAST
C:
[142-202]
------------------------------------
S
E
K
Y
G
D
I
A
L
K
K
-
K
L
E
Q
N
T
K
K
L
D
E
E
-------
S
----
S
Q
L
E
T
T
T
R
S
I
D
S
A
D
D
L
D
Q
F
I
K
N
Y
L
D
--
I
R
T
Q
Y
H
L
R
R
E
K
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
44.01
8%
-162
- C3 -
-
5DO7
-
ABCG8_HUMAN
D:
[480-671]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Y
Y
E
L
E
D
G
L
Y
T
T
-
G
P
Y
F
F
A
K
I
L
G
E
L
-
P
E
H
C
A
Y
I
I
I
Y
G
M
P
T
Y
W
----
L
A
N
L
R
---
P
G
---------------
L
-
Q
P
F
L
L
H
F
L
L
V
W
L
V
V
F
C
C
R
I
M
A
L
A
A
A
A
L
L
P
T
F
H
M
A
S
F
F
S
N
A
L
Y
-----
N
-
S
-----
F
Y
L
A
GG
F
M
I
N
L
S
S
L
-
W
T
V
-
P
A
W
I
S
K
V
S
F
L
R
W
C
F
E
G
L
M
K
I
--
Q
F
--
S
R
R
T
Y
K
M
P
L
GNL
T
I
A
V
S
GD
K
I
L
S
--------------------------
V
M
E
L
-----------------
D
S
Y
P
L
Y
A
I
Y
L
I
V
I
G
L
S
G
G
F
M
V
L
Y
Y
V
S
L
R
F
I
K
Q
K
P
------