@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VSX9: (2017-12-10 )
MEQIRPFPPTDFIDQADDEEATRLTPAPDLMDWVVKNYLTVDGELYNPDHDHIAELIHENEGFLAFAWASQACTVKKQMVSGQCEKVMFNVGGWRKARQEQQMRDWFGYVPVYLITIDASYCEQATDRDFCALIEHELYHIGVERDEDGEPLYSEMTGLPKHYLAGHDVEEFVGVVKRWGADENVKRLIEVAKQAPFVSDVNISKCCGTCLIN
Atome Classification :
(20 SA)
------------------------------------------------------------------------------.........10........20........30.-----------------.......40........50..--------......60...--.....70.....--...80........90.-.-......100.......110.......120....-....130.......140....--....150-------------.....---....160....-----...170----.......-.180..-......190.......200-........210.-------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
------------------------------------------------------------------------------MEQIRPFPPTDFIDQADDEEATRLTP
A
P
D
L
M
D
-----------------
W
V
V
K
N
Y
L
TVDGELYNP
D
H
D
H
I
--------
A
E
L
I
HENE
G
F
L
--
A
F
A
WASQ
A
C
T
V
K
--
K
Q
M
V
SG
Q
C
E
K
V
MFNVG-
G
-
W
R
K
A
R
Q
E
Q
Q
M
R
D
W
FGY
V
P
V
Y
L
I
T
I
D
A
S
-
Y
C
E
QA-T
D
R
D
F
C
A
L
I
E
H
E
L
Y
H
-IGVER--DEDGE---------------
P
L
Y
S
E
---MTGL
P
K
H
Y
LAG-----H
D
V
E
E
-----
F
V
G
V
V
K
R-WG-A
D
E
-
N
V
K
R
L
I
E
V
A
K
QAPFVSDV--
N
I
S
K
C
C
G
TCLIN-------------------------------------------------------------------------------------------------------------------------------
24
Fugue
60.10
15%
-72
- C3 -
-
5M1H
-
A:
[1-180]
--------------------------------------------------------------------------------
P
I
G
T
V
I
P
I
Q
H
I
R
S
V
T
G
E
P
P
R
N
---
P
R
E
I
P
I
-----------------
W
L
G
R
N
A
P
A
I
D
G
V
F
P
V
T
T
P
D
L
R
--------
C
R
I
I
N
A
I
L
G
G
------------
N
I
G
--
L
S
L
T
P
G
D
C
L
T
---------
W
D
S
A
V
A
T
L
F
I
R
T
-
H
G
T
F
P
M
H
Q
L
G
N
V
I
K
-
G
I
V
D
Q
-
E
G
-------
V
A
T
A
Y
T
-
L
G
M
M
L
--
S
G
Q
N
------------------
Y
Q
L
---
V
S
G
I
I
R
G
Y
L
P
G
-----
Q
A
V
V
T
-----
A
L
Q
Q
R
L
D
-
Q
E
-
I
D
D
-
Q
T
R
A
E
T
F
I
Q
H
L
N
A
V
Y
E
I
L
--
G
L
N
A
R
G
Q
S
I
R
L
E
-------------------------------------------------------------------------------------------------------------------------------
26
Fugue
58.07
20%
32
* C5 *
-
4QA5
3
HDAC8_HUMAN
A:
[14-377]
----------------------------L
V
P
V
Y
I
Y
S
P
E
Y
V
S
M
C
D
S
LAKIPK
R
A
S
M
V
H
S
L
I
E
A
Y
A
L
H
K
Q
M
R
I
V
K
P
K
V
A
S
M
E
E
M
A
T
F
H
T
D
A
Y
L
Q
H
L
Q
K
V
S
Q
E
G
D
D
D
H
P
D
S
I
E
------------------------------
Y
G
L
G
Y
D
C
P
--------
A
-----
T
E
G
I
F
--
D
Y
A
A
A
I
G
G
A
T
I
T
A
A
Q
C
L
I
D
G
M
C
K
V
A
I
N
W
S
G
-
G
-
W
H
H
A
K
K
D
E
A
--
S
G
F
C
Y
L
N
D
A
V
L
G
I
L
R
L
---
R
R
K
-
F
E
R
I
L
Y
V
D
L
D
--
L
H
H
G
D
G
V
E
D
T
F
S
F
T
S
K
---------------
V
M
T
V
S
---
L
H
K
F
S
P
G
F
F
P
G
-----
T
-----------
G
D
V
S
D
-
V
G
-
L
G
K
-
G
R
Y
Y
S
V
N
V
P
I
Q
-
D
G
I
Q
D
E
--
K
Y
Y
Q
I
C
E
S
V
L
K
E
V
Y
Q
A
FNPK
A
V
V
L
Q
L
G
ADTIAGDPMCSFNMT
P
V
G
I
G
K
C
L
K
Y
I
L
Q
W
QLA
T
L
I
L
G
G
G
GFN
L
A
N
T
A
R
C
W
T
Y
L
T
G
V
I
L
G
K
T
L
S
SEIPDHEFFTAYGPDYVL
E
I
T
P
S
CRPDRNE
P
H
R
I
Q
Q
I
L
N
Y
I
K
G
N
L
K
HVV
25
Fugue
51.95
17%
-71
- C3 -
-
2CWO
-
P21_BYVU
A:
[1-177]
------------------------------------------------------------------------------
M
K
F
F
L
K
----------
D
G
E
T
S
R
A
L
S
R
S
E
S
L
L
R
-----------------
R
V
-
K
E
L
G
T
------
N
S
Q
Q
S
E
I
--------
S
E
C
V
D
E
F
N
E
L
A
--
S
F
N
H
L
L
V
T
V
E
H
R
--
E
W
M
------------------
E
Q
R
I
G
E
M
L
K
E
I
R
A
F
L
K
V
R
V
V
T
---
P
-
M
H
K
E
T
-
A
S
D
T
L
N
A
F
L
E
E
Y
C
R
I
-
T
G
L
A
R
--
E
D
A
L
R
---------------
E
---
K
---
M
R
K
V
K
S
V
V
L
F
H
-----
H
S
E
L
L
-----
K
F
E
V
T
E
N
M
F
S
-
Y
T
E
-
L
L
K
L
N
L
S
L
R
V
I
S
S
Q
I
L
G
M
--
A
I
-----------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
49.21
19%
-390
- C4 -
-
4JIX
1
Y123_METJA
B:
[47-78]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
K
T
L
R
L
N
K
Y
-
V
V
E
N
F
-
D
E
E
L
L
H
Y
I
I
L
H
E
L
I
H
-
F
K
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
48.57
19%
-379
- C4 -
-
4JIX
3
Y123_METJA
A:
[47-78]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
K
T
L
R
L
N
K
Y
-
V
V
E
N
F
-
D
E
E
L
L
H
Y
I
I
L
H
E
L
I
H
-
F
K
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
48.48
12%
-46
- C- -
-
1JFU
-
TLPA_BRADU
A:
[5-180]
----------------------------------------------------------------------------------
T
G
D
P
A
C
R
A
A
V
A
T
A
Q
K
I
A
P
L
A
H
G
E
V
A
A
L
T
-----------------
M
A
S
A
P
L
K
L
P
D
L
A
F
E
D
A
D
G
K
P
K
--------
K
L
S
D
F
R
G
K
T
L
L
--
V
N
L
W
A
T
W
-
C
----------
V
P
C
R
K
E
M
P
A
L
D
-
E
-
L
Q
G
K
L
S
G
P
---------
N
F
E
V
V
A
I
N
I
D
-
T
R
D
P
E
-
K
P
K
T
F
L
K
E
A
N
L
T
R
L
G
-
Y
F
N
D
Q
--
K
A
K
V
F
---------------
Q
D
L
K
A
I
GR
A
L
G
M
P
T
S
V
L
V
D
-----
P
Q
G
C
E
-----
I
A
T
I
A
G
P
-
A
E
W
A
S
E
-
D
A
L
K
L
I
R
A
A
T
G
----------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
47.47
21%
-370
- C4 -
-
4QHJ
-
Y1213_METJA
A:
[45-77]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
K
T
I
Y
I
N
K
N
-
I
L
P
Y
L
-
S
D
E
E
I
R
F
I
L
A
H
E
L
L
H
-
L
K
Y
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
46.89
14%
-99
- C3 -
-
1EWX
1
?
A:
[1-144]
------------------------------------------------------------------------------
S
G
L
D
K
Y
L
P
G
I
E
K
L
R
R
------------------------------------------------
G
D
G
E
V
E
V
--------
K
S
L
--
A
G
K
L
V
F
--
F
Y
F
S
A
S
-
W
C
----------
P
P
C
R
G
F
T
P
Q
L
I
-
E
-
F
Y
D
K
F
H
E
S
K
N
------
F
E
V
V
F
C
T
W
D
E
E
----
E
D
-
G
F
A
G
Y
F
A
--
K
M
P
W
L
A
-
V
P
F
A
Q
--
S
E
A
V
Q
---------------
K
L
S
K
H
F
N-
V
E
S
I
P
T
L
I
G
V
D
-----
A
D
S
---------
G
D
V
V
T
-
T
R
-
A
R
A
-
T
L
V
K
D
P
E
-
G
E
Q
F
P
W
K
D
A
----------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
46.61
22%
-387
- C4 -
-
4QHI
1
Y1213_METJA
B:
[46-77]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
I
Y
I
N
K
N
-
I
L
P
Y
L
-
S
D
E
E
I
R
F
I
L
A
H
E
L
L
H
-
L
K
Y
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
43.57
12%
2
- C5 -
-
2Q7E
12
PYLS_METMA
A:
[25-291]
-------------------------------------------------------------------PALT
K
S
Q
T
D
R
L
E
V
L
L
N
P
K
D
E
K
P
F
R
E
L
E
S
E
L
L
S
R
R
K
K
D
L
Q
Q
I
Y
A
EEREN
Y
L
G
K
L
E
R
E
I
T
R
F
F
V
D
R
G
F
L
E
I
K
S
P
I
L
I
P
L
E
Y
I
E
R
M
GIDNLS
K
Q
I
F
R
V
D
K
N
F
C
LR
P
M
L
A
P
N
L
Y
N
Y
L
R
--
K
L
D
R
A
L
P
D
P
I
K
I
F
E
I
G
P
C
-
Y
R
K
E
S
D
G
K
E
H
L
E
E
F
T
M
L
N
F
C
Q
M
G
-------
S
G
C
-
T
R
E
N
L
E
S
I
I
T
D
F
L
N
H
-
L
G
I
D
F
--
K
I
V
G
D
S
C
MVYGD
T
L
D
V
M
HGD
L
E
L
S
S
---
A
V
V
G
P
I
P
L
D
R
E
-----
W
G
I
D
K
P
W
I
G
A
G
F
G
L
E
R
L
-
L
K
-
V
K
H
-
D
F
K
N
I
K
R
A
A
R
S
E
S
Y
Y
N
G
I
--
S
T
N
L
---------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
42.21
25%
-318
- C4 -
-
4JIU
-
?
A:
[37-68]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
G
T
I
T
L
D
P
A
-
V
-
L
N
L
-
E
E
E
E
M
F
Y
I
L
I
H
E
L
A
H
-
L
K
A
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
40.90
21%
-250
- C4 -
-
3CQB
2
HTPX_VIBPA
A:
[65-97]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
S
L
V
A
V
S
T
G
-
L
L
H
N
M
-
T
R
D
E
A
E
A
V
L
A
H
E
V
S
H
-
I
A
N
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
37.69
15%
-285
- C4 -
-
4IL3
-
?
A:
[273-313]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
R
I
V
L
F
D
T
-
L
V
N
S
N
-
S
T
D
E
I
T
A
V
L
A
H
E
I
G
H
-
W
Q
K
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
36.50
25%
-325
- C4 -
-
5SYT
1
FACE1_HUMAN
A:
[324-343]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
-
K
N
E
E
V
L
A
V
L
G
H
E
L
G
H
-
W
K
L
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
35.48
7%
-7
- C2 -
-
2AWI
-
?
A:
[2-301]
FK
I
G
S
V
L
K
Q
I
R
Q
E
L
NYHQIDLYSGIMS
K
S
V
Y
I
K
V
E
A
DS
R
P
I
S
V
E
E
L
S
K
F
S
E
R
L
GVN
F
F
E
I
L
N
R
A
GMNSVN
E
T
G
K
E
K
L
L
I
S
K
I
F
T
N
P
D
L
F
D
K
N
F
Q
R
I
E
P
K
R
L
T
S
L
Q
Y
F
S
I
Y
-----------------
L
G
Y
I
S
I
A
H
H
Y
N
I
E
V
P
T
F
N
K
T
I
--------
T
S
D
L
K
H
L
Y
D
K
R
--
T
T
F
F
G
I
D
C
E
I
V
S
--
N
L
L
N
V
L
P
Y
E
E
V
S
S
I
I
K
-
P
M
Y
P
I
V
D
S
F
G
K
D
Y
D
L
T
I
Q
T
V
L
K
N
A
L
T
I
S
I
M
N
R
N
L
K
-
E
A
Q
Y
Y
I
N
Q
F
E
H
L
K
T
I
-
K
N
I
S
I
--
N
G
Y
Y
D
---------------
L
E
I
N
Y
---
L
K
Q
I
Y
Q
F
L
T
D
K
N
I
D
S
Y
L
N
A
V
N
-----
I
I
N
I
F
K
I
-
I
G
-
K
E
D
-
I
H
R
S
L
V
E
E
L
T
K
I
S
A
K
E
K
F
--
T
P
P
K
E
V
T
M
Y
Y
E
N
-------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
35.02
12%
-56
* C4 *
-
2V4X
-
A:
[17-61]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Q
L
K
E
-----
L
K
I
A
C
S
Q
-
Y
G
-
P
T
A
P
F
T
I
A
M
I
E
N
L
G
T
Q
A
L
P
P
N
D
W
K
Q
T
A
R
A
C
L
------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
34.88
15%
-166
- C4 -
-
3C37
1
?
A:
[80-130]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
G
G
R
V
Y
V
H
T
G
-
L
L
K
A
A
D
N
E
T
E
L
A
G
V
L
A
H
E
I
N
H
-
A
V
A
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
33.64
28%
-117
- C4 -
-
4KK0
-
TSC1_SCHPO
A:
[109-173]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
---------------
P
V
F
S
D
---
L
K
S
I
L
F
Y
I
L
I
F
-----
H
D
E
D
E
-----
W
G
G
D
L
R
R
-
E
C
-
A
E
E
-
T
I
T
R
L
V
D
L
-------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
33.57
15%
-226
- C4 -
-
4IL3
-
?
B:
[273-305]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
R
I
V
L
F
D
T
-
L
V
N
S
N
-
S
T
D
E
I
T
A
V
L
A
H
E
I
G
H
-
W
Q
K
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
33.40
28%
-112
- C4 -
-
4KK1
-
TSC1_SCHPO
A:
[109-173]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
---------------
P
V
F
S
D
---
L
K
S
I
L
F
Y
I
L
I
F
-----
H
D
E
D
E
-----
W
G
G
D
L
R
R
-
E
C
-
A
E
E
-
T
I
T
R
L
V
D
L
-------------------------------------------------------------------------------------------------------------------------------------------------------