@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VT49: (2017-12-11 )
MFASILRELNYLRSNKWDSCMVTLIPAFIIFLFSSMFYAGKAEHLPIAIIDQDQSELSRNIGKYLSLNHTVDVKTITTSSSEAERLLNETKIWGYIFIPDGAEKRFVKAQDAQISIAFNQSFFSVGNTISSAMLVSTLNALADYAGQNYLANNIPYLDVPTAHVKISTLYNPSMSYEFYLEPFMVPAVLHLLLCCCVAFAIGQEIKRGTLTQWVNRESFIQGLLAKNLLYSFIFCFWTWLWMFWLVEIRGWFVAGSLSFLLAAQFLLYFSYALISSTVILATKNLSKTFGFIAVYGGSSLSFAGVTLPLNNAPIFTKFWSLIIPYTPYAKLQTEQWVIGSPLFISMSPFLILIGYCLIYFFLSCLLLKKLVQGATP
Atome Classification :
(20 SA)
-----.........10..-......20...-.....30........40........50........-60......-..70.......-.80....-.----...90........100.......110....--...120.......-130---.--------......140..-.....150.-.--.....160....------...170.......180.-......--190.......200.......210.-....-..-220.......230--........240.......250.-.-.....260---.......--------..270.......280.......290......-.---------300-..-....-.310........320.....--...330.-------......340------------------------.--------------------------------......350..-.....360.......370....
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-----
M
F
A
S
I
L
R
E
L
N
Y
L
R-SNKW
D
S
C
M
V
T
L
-
I
P
A
F
I
I
F
L
F
S
S
M
F
YAGKAEH
L
P
I
A
I
IDQ
D
Q
S
E
L
S
R
-
N
I
G
K
Y
LSL-N
H
T
V
D
V
K
T
ITT-S
S
S
E
A
E
R
-
L
----
L
N
ET
K
I
W
G
Y
I
F
IPDGAEK
R
F
V
K
AQD
A
Q
I
S
I
--
A
FN
Q
S
F
F
SV
G
N
T
I
-
S
S
A
---
M
--------
L
V
S
T
L
N
A
L
A
D
Y-AGQNYLANN-I--PYLDVPT
A
H
V
K
I
------
S
T
LYNPSM
S
Y
E
F
Y
L
E
P
F
-
M
V
P
A
V
L
--
H
L
L
L
C
C
C
V
A
F
A
I
G
Q
E
I
K
R
G
T
L
T
Q
W
-
V
N
R
E
-
S
F
-
I
Q
G
L
L
A
K
N
L
L
Y
S
---
F
I
F
C
F
W
T
W
L
W
M
F
W
L
V
E
IR
G
W
F
V
-
A
-
G
S
L
S
F
L
-----
L
A
A
Q
F
L
L
--------
Y
F
S
Y
A
L
I
S
S
T
V
I
L
A
TKNLSK
T
F
G
F
I
A
V
YGGS-S---------
L
S
F
-
A
G
-
V
T
L
P-LNN-A
P
I
F
T
K
F
W
S
L
-IIPYT--PYAK
L
Q
T-------E
Q
W
V
IGS
P
L
------------------------
F
--------------------------------
I
SM
S
P
F
L
I
L
I
G
-
Y
C
L
I
Y
F
F
L
S
C
L
L
L
K
K
L
VQGATP
32
Fugue
65.19
18%
-55
- C2 -
-
5A07
1
KTR4_YEAST
A:
[40-434]
D
H
D
A
E
V
L
D
S
I
M
D
R
L
H
E
P
L
-
Y
E
K
-
D
T
F
D
P
N
E
-
V
L
A
E
N
K
Q
L
Y
E
E
F
L
L
Q
E
I
S
E
P
K
V
D
N
L
V
R
S
G
D
P
L
A
G
K
-
A
K
G
T
I
L
S
L
-
V
R
N
S
D
L
E
D
I
I
S
-
S
I
Q
Q
L
E
E
-
E
----
Y
N
K
N
F
G
Y
P
Y
T
F
L
N
D
---
E
E
F
T
D
E
F
K
D
G
I
K
S
--
I
L
P
K
D
R
V
V
E
F
G
T
I
-
G
P
D
NWN
M
--------
P
D
S
I
D
R
E
R
Y
D
Q
-
E
M
D
K
M
S
K
E
N
-
I
--
Q
Y
A
E
V
E
S
Y
H
-
N
M
------
C
R
F
Y
S
K
E
F
Y
H
H
P
L
L
S
K
Y
-
K
Y
V
W
R
L
E
P
N
V
N
F
Y
C
K
I
N
Y
D
---------
V
F
Q
F
-
M
N
K
N
-
D
K
-
I
Y
G
F
V
L
--
N
L
Y
D
SPQ
T
I
E
T
L
W
T
S
T
M
D
F
V
E
E
H
P
N
Y
L
N
V
-
N
-
G
A
F
A
W
L
K
DNSQ
N
P
K
N
Y
D
Y
T
QGYSTCH
F
W
T
N
F
E
I
V
D
L
D
F
L
R
S
E
P
Y
E
K
Y
M
Q
Y
L
E
E
K
G
G
F
-
Y
YERWG
D
A
P
V
R
S
L
-
A
L
-
A
L
F
A
D
K
S
S
-
I
H
W
F
R
D
I
G
Y
H
-
H
T
P
Y
T
N
C
P
T
C
P
A
D
S
-------
D
R
C
N
-
G
N
C
V
------------------------
P
--------------------------------
G
K
F
T
P
W
S
D
L
D
N
Q
N
C
Q
A
T
W
I
R
H
S
M
S
E
E
E
L
E
M
Y
---
7
PsiBlast_PDB
43.09
22%
-132
- C3 -
-
3CNI
-
?
A:
[13-103]
-----------------------------------------------------
V
A
I
V
R
E
D
T
G
T
I
A
E
-
L
A
E
K
--
A
L
-
G
N
M
V
D
I
V
Y
A
G
S
-
D
L
K
E
A
E
E
-
A
----
V
K
K
E
K
A
P
A
I
I
V
I
P
K
G
F
S
Q
S
L
E
S
G
E
K
A
R
L
E
I
--
V
----
W
Y
L
R
G
T
G
L
-
S
E
A
---
V
--------
S
T
G
T
I
S
S
L
I
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
41.55
13%
-176
- C3 -
-
5DO7
-
ABCG5_HUMAN
A:
[439-649]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
N
L
F
P
V
L
R
A
V
S
D
Q
E
S
Q
D
G
L
Y
-
Q
K
-
W
Q
M
M
L
A
Y
A
L
H
V
L
---
P
F
S
V
V
A
T
M
I
F
S
S
V
C
Y
W
T
L
G
L
H
P
E
V
-
A
R
F
G
Y
F
-----
S
A
A
L
L
A
P
--------
H
L
I
G
E
F
L
T
L
V
L
L
G
I
V
Q
N
P
N
I
V
N
S
V
V
A
L
L
S
I
A
-
G
---------
V
L
V
G
S
G
-
F
L
R
N
-
I
Q
E
-
M
P
I
P
F
K
I
I
S
Y
-
F
T
F
Q
K
--
Y
C
S
E
I
L
V
-------
V
N
E
F
Y
G
L
N
F
------------------------
T
CAFTQ
G
I
Q
F
I
E
K
TCPGATS-------------
R
F
T
M
N
F
L
I
L
Y
S
-
F
I
P
A
L
V
I
L
G
I
V
V
F
K
I
R
D
H
L
I
--
13
HHSearch
40.78
13%
-173
- C3 -
-
5DO7
-
ABCG5_HUMAN
C:
[439-649]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
N
L
F
P
V
L
R
A
V
S
D
Q
E
S
Q
D
G
L
Y
-
Q
K
-
W
Q
M
M
L
A
Y
A
L
H
V
L
---
P
F
S
V
V
A
T
M
I
F
S
S
V
C
Y
W
T
L
G
L
H
P
E
V
-
A
R
F
G
Y
F
-----
S
A
A
L
L
A
P
--------
H
L
I
G
E
F
L
T
L
V
L
L
G
I
V
Q
N
P
N
I
V
N
S
V
V
A
L
L
S
I
A
-
G
---------
V
L
V
G
S
G
-
F
L
R
N
-
I
Q
E
-
M
P
I
P
F
K
I
I
S
Y
-
F
T
F
Q
K
--
Y
C
S
E
I
L
V
-------
V
N
E
F
Y
G
L
N
F
------------------------
T
CGSMCAFTQ
G
I
Q
F
I
E
K
TCPGATS---------
R
F
T
M
N
F
L
I
L
Y
S
-
F
I
P
A
L
V
I
L
G
I
V
V
F
K
I
R
D
H
L
I
--
26
Fugue
40.30
17%
-22
- C3 -
-
3CNI
-
?
A:
[11-155]
---------------------------------------------------
Q
K
V
A
I
V
R
E
D
T
G
T
I
A
E
-
L
A
E
K
A
L
G
N
M
V
D
I
V
Y
A
G
S
----
D
L
K
E
A
E
E
-
A
----
V
K
K
E
K
A
P
A
I
I
V
I
P
K
G
F
S
Q
S
L
E
S
G
E
K
A
R
L
E
I
--
V
W
Y
L
R
G
T
G
L
S
E
A
V
-
S
T
G
---
T
--------
I
S
S
L
I
E
S
L
K
V
Q
-
L
A
S
F
L
L
N
D
P
-
K
K-
A
Q
L
L
F
D
P
L
E
I
V
Q
------
H
T
Y
L
R
G
S
L
F
K
N
H
S
P
E
A
I
M
N
V
F
Y
S
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
40.23
12%
-184
- C3 -
-
5DO7
-
ABCG8_HUMAN
B:
[472-671]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
C
Y
S
E
R
A
M
L
Y
Y
E
L
E
D
G
L
Y
T
T
-
G
P
Y
F
F
A
K
I
L
G
E
L
---
P
E
H
C
A
Y
I
I
I
Y
G
M
P
T
Y
W
L
A
N
L
R
P
G
L
-
Q
P
F
L
L
H
-----
F
L
L
V
W
L
V
--------
V
F
C
C
R
I
M
A
L
A
A
A
A
L
L
P
T
F
H
M
A
S
F
F
S
N
A
L
Y
N
S
-
F
---------
Y
L
A
-
G
G
-
F
M
I
N
-
L
S
S
-
L
W
T
V
P
A
W
I
S
K
-
V
S
F
L
R
--
W
C
F
E
G
L
M
-------
K
I
Q
F
S
R
R
T
Y
K
M
P
L
G
NLTIAVSGD
K
I
L
S
V
M
ELDS
Y
--------------------------------
P
L
Y
A
I
Y
L
I
V
I
G
-
L
S
G
G
F
M
V
L
Y
Y
V
S
L
R
F
I
K
Q
K
P
--
31
Fugue
40.18
17%
210
- C- -
-
4RWR
-
?
A:
[63-331]
-----
V
Y
R
E
K
Q
K
K
V
E
S
L
P
M
E
E
Y
V
T
G
V
V
A
S
E
M
N
A
S
F
E
I
E
A
L
K
A
Q
A
L
A
A
R
T
F
V
V
Q
------------
R
M
L
S
G
G
K
K
N
N
-
A
D
V
T
D
T
D
Q
V
Y
K
-
S
K
E
E
L
K
K
-
Q
----
W
G
-----------
N
N
Y
E
N
N
L
K
K
I
E
E
A
V
S
K
T
--
A
--
G
Q
V
L
T
Y
E
G
K
P
-
I
S
A
---
S
--------
F
F
S
T
S
N
G
R
T
E
N
-
A
-
A
D
Y
W
G
N
D
-
Y
--
P
Y
L
K
S
V
D
S
P
W
D
Q
------
A
-------
S
P
K
F
T
S
E
Q
I
-
F
T
V
A
D
F
--
Q
K
R
L
G
-------
V
K
V
L
A
D
G
K
V
G
D
I
-
K
G
R
T
-----
E
G
K
R
V
K
D
V
A
F
Q
---
G
-------------
K
T
L
T
G
R
D
V
-
R
-
D
K
L
E
L
R
-----
S
S
-------------
D
F
T
W
K
Q
E
G
D
K
I
V
V
T
T
K
G
F
G
--------
H
G
V
G
M
S
-----------------
Q
Y
G
-
A
N
G
M
A
A
E
G
K
K
Y
T
D
I
-
V
A
H
Y
Y
--
K
G
V
E
I
K
T
M------
N
D
Y
-------------------------------------------------------------------------------------------------
15
HHSearch
39.11
17%
-83
- C3 -
-
3CNI
-
?
A:
[11-107]
---------------------------------------------------
Q
K
V
A
I
V
R
E
D
T
G
T
I
A
E
-
L
A
E
K
A
L
G
---
N
M
V
D
I
V
Y
A
G
S
-
D
L
K
E
A
E
E
-
A
----
V
K
K
E
K
A
P
A
I
I
V
I
P
K
G
F
S
Q
S
L
E
S
G
E
K
A
R
L
E
I
V
W
Y
L
R
G
T
G
L
-
S
E
A
V
S
-
T
G
T
---
I
--------
S
S
L
I
E
S
L
K
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
37.69
12%
-184
- C3 -
-
5DO7
-
ABCG8_HUMAN
D:
[472-671]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
C
Y
S
E
R
A
M
L
Y
Y
E
L
E
D
G
L
Y
T
T
-
G
P
Y
F
F
A
K
I
L
G
E
L
---
P
E
H
C
A
Y
I
I
I
Y
G
M
P
T
Y
W
L
A
N
L
R
P
G
L
-
Q
P
F
L
L
H
-----
F
L
L
V
W
L
V
--------
V
F
C
C
R
I
M
A
L
A
A
A
A
L
L
P
T
F
H
M
A
S
F
F
S
N
A
L
Y
N
S
-
F
---------
Y
L
A
-
G
G
-
F
M
I
N
-
L
S
S
-
L
W
T
V
P
A
W
I
S
K
-
V
S
F
L
R
--
W
C
F
E
G
L
M
-------
K
I
Q
F
S
R
R
T
Y
K
M
P
L
GNL
T
I
A
V
S
GD
K
I
L
S
V
M
ELDS
Y
--------------------------------
P
L
Y
A
I
Y
L
I
V
I
G
-
L
S
G
G
F
M
V
L
Y
Y
V
S
L
R
F
I
K
Q
K
P
--
8
HHSearch
36.13
8%
-108
- C3 -
-
5XJY
2
?
A:
[533-1119]
------------------------------------------------------------------------------------
P
I
A
-
T
E
V
W
L
I
N
-
K
S
M
E
L
L
D
E
R
K
F
W
A
G
I
V
F
T
G
I
T
P
G
S
I
E
L
P
H
H
V
K
Y
K
I
--
R
M
D
I
D
N
V
E
R
T
N
K
I
K
D
G
Y
---
W
DPGPRADP
F
E
D
M
R
Y
V
W
G
G
F
A
Y
L
Q
D
V
V
E
Q
A
I
I
R
V
L
T
G
T
E
K
K
T
G
V
Y
M
Q
Q
MPYP
C
Y
V
D
D
I
F
L
R
V
M
S
R
S
M
P
L
-
F
M
T
L
A
W
--
I
Y
S
V
A
V
-
I
I
K
G
I
V
Y
E
K
E
A
R
L
K
E
T
M
R
I
M
G
L
-
D
N
-
S
I
L
W
F
S
W
F
I
S
S
----
L
I
P
L
L
V
S
A
G
L
L
V
V
I
L
K
L
G
N
L
L
P
-
Y
-
S
D
P
S
V
V
-----
F
V
F
L
S
V
F
--------
A
V
V
T
I
L
Q
C
F
L
I
S
T
L
F
S
R
A
N
L
A
A
A
C
G
G
I
I
Y
F
T
-
L
---------
Y
L
P
-
Y
V
L
C
V
A
W
-
Q
D
Y
-
V
G
F
T
L
K
I
F
A
S
L
L
S
P
V
A
--
F
G
F
G
C
E
Y
F
A
L
F
EEQ--------------------------------------------------------------------
G
F
N
L
T
T
S
V
S
-
M
M
L
F
D
T
F
L
Y
G
V
M
T
W
Y
I
E
A
V
F
--
10
HHSearch
35.55
9%
-145
- C3 -
-
5NJG
1
?
B:
[451-663]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
A
V
E
L
F
V
V
E
K
K
L
F
I
H
E
Y
I
S
G
Y
-
Y
R
V
S
S
Y
F
L
G
K
L
L
S
D
L
L--
P
M
R
M
L
P
S
I
I
F
T
C
I
V
Y
F
M
L
G
L
K
P
-
K
A
D
A
F
F
V
M
-----
M
F
T
L
M
M
V
--------
A
Y
S
A
S
S
M
A
L
A
I
A
A
G
Q
S
V
V
S
V
A
T
L
L
M
T
I
C
F
V
F
-
M
---------
M
I
F
-
S
G
-
L
L
V
N
-
L
T
T
-
I
A
S
W
L
S
W
L
Q
Y
-
F
S
I
P
R
--
Y
G
F
T
A
L
Q
-------
H
N
E
F
L
G
Q
N
F
------------------------
C
PGLNATGNNPCNYATCTGEEYLVKQGIDLSPW
G
L
W
K
N
H
V
A
L
A
C
-
M
I
V
I
F
L
T
I
A
Y
L
K
L
L
F
L
K
K
Y
---
9
HHSearch
35.50
9%
-145
- C3 -
-
5NJ3
1
?
A:
[451-663]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
A
V
E
L
F
V
V
E
K
K
L
F
I
H
E
Y
I
S
G
Y
-
Y
R
V
S
S
Y
F
L
G
K
L
L
S
D
L
L
--
P
M
R
M
L
P
S
I
I
F
T
C
I
V
Y
F
M
L
G
L
K
P
-
K
A
D
A
F
F
V
M
-----
M
F
T
L
M
M
V
--------
A
Y
S
A
S
S
M
A
L
A
I
A
A
G
Q
S
V
V
S
V
A
T
L
L
M
T
I
C
F
V
F
-
M
---------
M
I
F
-
S
G
-
L
L
V
N
-
L
T
T
-
I
A
S
W
L
S
W
L
Q
Y
-
F
S
I
P
R
--
Y
G
F
T
A
L
Q
-------
H
N
E
F
L
G
Q
N
F
------------------------
C
PGLNATGNNPCNYATCT
G
E
E
Y
L
V
K
Q
GIDLS
P
W
G
L
W
K
N
H
V
A
L
A
C
-
M
I
V
I
F
L
T
I
A
Y
L
K
L
L
F
L
K
K
Y
---
4
PsiBlast_PDB
30.85
40%
-250
- C4 -
-
4FNP
-
AGAA_GEOSE
A:
[695-724]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
V
Y
G
G
D
-
E
---------
L
V
Y
-
A
G
-
V
A
L
P
-
Y
R
S
-
S
D
F
I
S
M
M
W
R
L
--------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
30.38
40%
-260
- C4 -
-
4FNQ
-
?
A:
[695-724]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
V
Y
G
G
D
-
E
---------
L
M
Y
-
A
G
-
V
A
L
P
-
Y
R
S
-
G
D
F
I
S
M
M
W
R
L
--------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
29.77
40%
-276
- C4 -
-
4FNR
-
AGAA_GEOSE
A:
[695-724]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
V
Y
G
G
D
-
E
---------
L
M
Y
-
A
G
-
V
A
L
P
-
Y
R
S
-
S
D
F
I
S
M
M
W
R
L
--------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
28.99
40%
-260
* C4 *
-
4FNT
-
AGAA_GEOSE
A:
[695-724]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
V
Y
G
G
D
-
E
---------
L
V
Y
-
A
G
-
V
A
L
P
-
Y
R
S
-
S
D
F
I
S
M
M
W
R
L
--------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
28.92
40%
-247
- C4 -
-
4FNS
-
AGAA_GEOSE
A:
[695-724]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
V
Y
G
G
D
-
E
---------
L
V
Y
-
A
G
-
V
A
L
P
-
Y
R
S
-
S
D
F
I
S
M
M
W
R
L
--------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
28.18
40%
-262
- C4 -
-
4FNU
-
AGAA_GEOSE
A:
[695-724]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
V
Y
G
G
D
-
E
---------
L
M
Y
-
A
G
-
V
A
L
P
-
Y
R
S
-
S
D
F
I
S
M
M
W
R
L
--------------------------------------------------------------------------------------------------------------------------
25
HHSearch
26.67
22%
-
- C1 -
-
2MFR
-
A:
[38-46]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
L
F
L
R
K
R
Q
P
---
17
HHSearch
25.89
15%
-35
- C3 -
-
2P0S
1
?
A:
[8-68]
-------------------------------------------------
D
M
K
T
I
A
I
A
D
R
T
G
E
-
Y
E
Q
-
L
F
K
E
-----
N
D
E
F
R
F
V
-
H
A
E
K
T
A
E
E
Y
R
K
M
G
----
A
D
K
S
G
I
D
A
V
L
E
I
R
Q
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------