@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : I3TZ21: (2017-12-15 )
MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASFDQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLLEHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYELFQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKSTYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEIFYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVGKIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVLLMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITFCQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN
Atome Classification :
(20 SA)
------------------------------------------------------------------------------------.........10.....---...20........30....---....40........50........60....-....------70........80...-.....90........100.......110.......120-.......-.-.130.-...---..-..140--.--...--...150....----...160.......170..-.....180.......190.......200.......210......---.220...-....230...---....240........250..-----.....260-------.......270-------........280..-.....-290--.......300..---..------...310.......320-..-.......330....-...-----340-.......-.350.......360.......370.......380.......390...---..------..400-........410.....-----..420------....-....430.--..---..--.-.-------.----440--.........450..------------.-....460.------...-..------.470.......480....-------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
------------------------------------------------------------------------------------M
K
I
E
A
L
L
E
R
K
E
Q
L
Q
I
L
---
I
L
R
N
L
V
LQGGT
A
S
I
N
G
L
R
E
---
H
V
Q
L
S
K
A
S
F
D
Q
Y
L
E
D
I
E
L
I
G
R
M
M
E
K
K
V
E
V
Q-RNE
Y
------
Q
A
L
L
V
LDEDV
S
L
E
K
I
-
L
L
F
L
L
Q
E
S
L
K
F
K
M
L
V
Y
L
L
EHQ
Q
V
S
I
V
R
L
A
T
A
FNI
S
E
---
S
S
V
F
R
K
I
-
K
-
E
L
N
-
Q
-
L
L
E
---EF-G
L
Q
IK--N--
G
Q
L--YG
E
E
L
Q
I
R
Y
F
----
Y
Y
E
L
F
Q
YIPEDQR
P
L
F
LQ-NTPEKR
P
F
I
L
G
L
D
R
V
L
E
T
TFTASA
E
A
Q
I
A
C
W
LGI
T
K
K
R
L
LNEKS---
T
Y
A
T
L
K
E
-
K
K
L
L
Y
QS
D
R
L
---
Y
Q
A
I
D
-
P
I
I
V
M
HLSRT
A
A
E
L
-----
N
V
Y
E
T
M
M
F
-------
Y
S
F
F
V
S
F
S
I--------V
D
E
E
I
F
Y
Q
YDLTR-SKKL
P
-
T
A
V
--
L
D
T
Y
I
R
E
T
M
L
WH---YR------PR
R
L
K
I
KEEKAV
G
Y
---
Q
I
-
S
QINN
E
W
F
F
F
V
G
K
I
-
E
V
Y
-----
E
R
--
D
R
L
L
E
Q
Q
-
Q
K
M
L
G
H
S
L
T
Q
L
L
A
K
L
Q
E
T
A
V
Q
Q
L
P
R
KRAEDS
E
L
S
Y
L
M
I
Q
YA
N
V
L
L
M
I
---
D
F
------YIAK--
P
V
V
I
G
I
DLESLP
I
Y
R
I
-----
A
F
Q
Q
-------
Y
L
I
R
-
E
L
RGI-G
G
--
I
E---IG--S-Y-------E----E----GKE
Y
D
L
V
I
T
F
C
QR
N
------------
K
-
K
Q
C
E
Y
Y
L
S
------
E
FA-S
P
------
Y
D
I
I
R
L
K
R
R
I
E
T
L
KKEKN-------------
8
HHSearch
68.08
13%
-60
- C5 -
-
5WAY
1
?
A:
[1-493]
--------------------------------------------------------------------------------------
M
R
D
L
L
S
K
K
S
H
R
Q
L
E
---
L
L
E
L
L
F
E
H
K
R
W
F
H
R
S
E
L
A
E
---
L
L
N
C
T
E
R
A
V
K
D
D
L
S
H
V
K
S
A
F
P
D
L
----
I
F
H
-
S
S
T
N
------
G
I
R
I
I
N
T
D
D
S
D
I
E
M
V
-
Y
H
H
F
F
K
H
S
T
H
F
S
I
L
E
F
I
F
F
N
E
G
C
Q
A
E
S
I
C
K
E
F
Y
I
S
S
---
S
S
L
Y
R
I
I
-
S
-
Q
I
N
-
K
-
V
I
K
R
--
Q
F
-
Q
F
E
V
S
LT
P
--
V
Q
I
--
I
G
N
E
R
D
I
R
Y
F
----
F
A
Q
Y
F
S
E
K
Y
Y
F
L
E
W
P
F
E
N
F
S
S
E
P
L
S
Q
L
L
E
L
V
Y
K
E
T
S
F
P
M
N
L
S
T
H
R
M
L
K
L
L
L
V
T
N
L
Y
R
I
K
F
G
H
F
---
M
E
V
--------------
F
LMQ
A
E
G
I
E
-
G
V
A
Q
S
F
E
S
E
Y
N
I
S
L
-----
D
E
E
V
V
C
Q
L
-------
F
V
S
Y
F
Q
K
M
F
--------
F
I
D
E
S
L
F
M
K
C
V
K
K
D
S
Y
V
E
K
S
Y
H
L
--
L
S
D
F
I
D
-
Q
I
S
V
K
---
Y
Q
------
I
-
E
I
--
E
N
K
D
N
L
I
W
---
H
L
----
H
N
T
A
H
L
Y
R
Q
E
L
-
F
T
E
FILFD
Q
K
--
G
N
T
I
R
N
F
-
Q
N
I
F
-
P
K
F
V
S
D
V
K
K
E
L
S
H
Y
L
E
T
L
-
E
V
C
S
S
S
M
M
V
N
H
L
S
Y
T
F
I
T
H
T
K
H
L
V
I
N
L
L
------
Q
N
Q
P
--
K
L
K
V
L
V
M
S
N
F
D
Q
Y
H
A
K
-----
F
V
A
E
-------
T
L
S
Y
-
Y
C
S
N
N
-
F
E
--
L
E
---
V
W
--
T
-
E
LELS
K
E
S
L
----
E
----
D
S
P
Y
D
I
I
I
S
N
F
I
I
P
PI----------
E
-
N
K
R
L
I
Y
S
N
------
N
I
N
-
T
V
------
S
L
I
Y
L
L
N
A
M
M
F
I
R
L
D
E
---------------
5
HHSearch
66.97
16%
-17
- C5 -
-
4R6I
1
ATXA_BACAN
B:
[4-476]
------------------------------------------------------------------------------------
M
L
T
P
I
S
I
E
K
E
H
I
R
L
I
N
---
L
L
H
F
I
N
E
Q
N
R
W
F
T
I
K
E
L
S
D
---
Y
L
Q
V
A
D
K
T
V
R
K
Y
L
K
L
L
E
D
E
I
P
P
S
-
W
--
N
L
L
V
Q
K
G
K
------
G
I
Y
L
K
K
P
L
N
E
S
L
S
F
V
-
E
S
K
I
L
R
K
S
L
N
L
Q
I
C
E
E
L
V
F
K
K
-
N
S
M
Q
S
L
A
Q
K
L
H
L
Q
V
---
G
A
L
Y
P
I
I
-
N
-
Q
I
N
-
Y
-
D
I
Q
---
S
S
-
H
L
N
I
K
--
K
KP
L
E
I
--
S
G
R
E
Q
D
V
R
V
F
----
M
L
R
L
Y
C
N
I
-
P
N
D
Y
W
P
F
P
Y
I
N
K
Q
N
I
T
D
L
I
N
K
M
E
K
I
L
N
V
Q
M
Y
T
Y
S
K
H
K
L
C
V
L
F
A
I
T
I
S
R
L
L
S
G
N
T
---
I
D
N
V
S
G
--
L
I
L
V
N
K
N
D
D
H
---
Y
K
T
V
A
-
S
I
T
S
E
L
Q
N
S
F
G
V
T
L
-----
H
E
T
E
I
S
F
L
-------
A
L
A
L
L
L
S
L
G
--------
N
S
I
T
---
N
K
T
L
-
T
-
S
Y
K
K
T
I
M
P
L
--
A
K
E
I
T
K
-
G
I
E
H
K
---
L
Q
------
L
-
G
I
--
N
Y
D
E
S
F
L
T
---
Y
V
-
V
-
L
I
I
K
K
A
L
D
K
N
F
I
-
Q
Y
Y
-----
N
Y
N-
I
K
F
I
R
H
I
-
K
Q
R
H
-
P
N
T
F
N
T
I
Q
E
C
I
S
N
L
N
Y
T
V
-
Y
S
H
F
D
C
Y
E
I
S
L
L
T
M
H
F
E
T
Q
R
M
L
F
------------
K
N
N
--
P
K
K
I
Y
V
Y
T
S
Q
G
C
I
H
R
E
-----
Y
I
S
A
-------
L
L
E
K
-
R
Y
N
G
L
-
I
K
--
I
V
---
R
N
--
T
I------------------
D
M
E
I
D
I
I
I
S
N
--------------------------------
E
F
P
-
T
E
------
R
D
F
H
E
I
K
K
-----------------------
7
HHSearch
63.27
13%
-61
- C5 -
-
5WAY
1
?
B:
[1-492]
--------------------------------------------------------------------------------------
M
R
D
L
L
S
K
K
S
H
R
Q
L
E
---
L
L
E
L
L
F
E
H
K
R
W
F
H
R
S
E
L
A
E
---
L
L
N
C
T
E
R
A
V
K
D
D
L
S
H
V
K
S
A
F
P
D
L
----
I
F
H
-------------
R
I
I
N
T
D
D
S
D
I
E
M
V
-
Y
H
H
F
F
K
H
S
T
H
F
S
I
L
E
F
I
F
F
N
E
G
C
Q
A
E
S
I
C
K
E
F
Y
I
S
S
---
S
S
L
Y
R
I
I
-
S
-
Q
I
N
-
K
-
V
I
K
R
--
Q
F
-
Q
F
E
V
S
LT
P
--
V
Q
I
--
I
G
N
E
R
D
I
R
Y
F
----
F
A
Q
Y
F
S
E
K
Y
Y
F
L
E
W
P
F
E
N
F
S
S
E
P
L
S
Q
L
L
E
L
V
Y
K
E
T
S
F
P
M
N
L
S
T
H
R
M
L
K
L
L
L
V
T
N
L
Y
R
I
K
F
G
H
F
---
M
E
V
------------
L
D
F
L
M
Q
A
E
G
I
E
-
G
V
A
Q
S
F
E
S
E
Y
N
I
S
L
-----
D
E
E
V
V
C
Q
L
-------
F
V
S
Y
F
Q
K
M
F
--------
F
I
D
E
S
L
F
M
K
C
V
K
K
D
S
Y
V
E
K
S
Y
H
L
--
L
S
D
F
I
D
-
Q
I
S
V
K
---
Y
Q
------
I
-
E
I
--
E
N
K
D
N
L
I
W
---
H
L
----
H
N
T
A
H
L
Y
R
Q
E
L
-
F
T
E
FILFD
Q
K
--
G
N
T
I
R
N
F
-
Q
N
I
F
-
P
K
F
V
S
D
V
K
K
E
L
S
H
Y
L
E
T
L
-
E
V
C
S
S
S
M
M
V
N
H
L
S
Y
T
F
I
T
H
T
K
H
L
V
I
N
L
L
------
Q
N
Q
P
--
K
L
K
V
L
V
M
S
N
F
D
Q
Y
H
A
K
-----
F
V
A
E
-------
T
L
S
Y
-
Y
C
S
N
N
-
F
E
--
L
E
---
V
W
--
T
-
E
LELS
K
E
S
L
----
E
----
D
S
P
Y
D
I
I
I
S
N
F
I
I
P
PI----------
E
-
N
K
R
L
I
Y
S
N
------
N
I
N
-
T
V
------
S
L
I
Y
L
L
N
A
M
M
F
I
R
L
D
----------------
32
Fugue
55.90
15%
-32
- C2 -
-
5DOQ
3
?
A:
[1-432]
-----------------------------------------------------------------------------MNGYDPV
L
L
S
R
I
L
T
E
L
T
L
T
V
H
I
I
Y
A
T
I
G
V
G
V
P
L
M
I
A
I
A
Q
W
V
G
I
R
K
NDM
H
Y
I
L
L
A
R
R
W
T
R
G
F
V
I
T
V
A
V
G
V
V
T
G
T
A
I
G
L
Q
-
L
S
L
L
W
P
N
F
M
Q
L
A
G
Q
V
I
S
L
P
L
F
M
E
T
F
-
A
F
F
F
E
A
I
F
L
G
I
Y
L
Y
T
W
D
R
F
E
N
Q
K
K
H
L
L
L
L
I
P
V
A
I
G
S
---
S
A
S
A
M
F
I
-
T
-
M
V
N
-
A
-
F
M
N
---
T
P
Q
G
F
E
L
K
--
N
--
G
E
L
--
V
N
--------------------
I
D
P
I
V
A
M
F
N
P
-
A
M
P
T
K
V
A
H
V
L
A
T
S
Y
-
M
T
S
A
F
V
L
A
S
I
A
A
W
H
L
W
K
G
--
N
R
H
I
Y
H
R
K
A
---
L
H
L
T
M
K
T
A
F
I
F
S
V
A
S
A
L
V
---
G
D
L
S
G
-
K
F
L
A
E
Y
Q
P
E
K
L
A
A
A
-----
E
W
H
F
E
T
S
S
-------
H
A
P
L
I
L
F
G
T
--------
L
E
E
D
N
E
V
K
Y
A
L
E
I
-
P
--
Y
A
-
L
S
I
--
L
A
H
N
H
P
A
A
V
V
T
G
---
L
N
------
D
I
P
E
D
E
R
P
P
L
Y
I
H
Y
---
L
F
-
D
V
M
V
T
I
G
V
F
L
M
V
V
A
-
A
V
Y
-----
W
L
--
G
S
I
F
-----------------
R
W
K
W
T
A
K
N
W
F
F
G
L
L
V
A
G
G
P
L
A
M
I
A
I
E
A
G
W
Y
L
A
E
V
--------------------------------------
G
R
Q
P
-------
W
I
----
L
R
G
Y
-
M
K
--
T
A
---
E
G
--
A
-------------------------------
T
T
------------
S
-
A
H
V
D
T
M
L
V
------
L
F
C
-
L
L
------
Y
I
V
L
V
I
A
S
A
T
V
L
I
R
M
F
R
R
NP-----------
35
Fugue
49.46
16%
1
- C6 -
-
4PE2
1
MALE_ECOLI
A:
[3-498]
-------------------------------------------------------------------------------------------
I
E
E
G
K
L
V
I
W
---
I
N
G
D
----
K
G
Y
N
G
L
A
E
V
G
K
---
K
F
E
K
D
T
-
G
I
K
V
T
V
E
H
P
D
K
L
E
E
K
F
P
Q
V
A
A
T
G
-
D
G
P
D
------
I
I
F
W
A
H
D
R
F
G
G
Y
A
Q
S
G
L
L
A
E
I
T
P
D
K
A
F
Q
D
K
L
Y
P
F
T
W
D
A
V
R
Y
N
G
K
L
I
A
Y
P
I
A
V
E
A
L
S
L
I
Y
N
K
D
-
L
-
L
P
N
-
P
-
P
K
T
---
W
E
-
E
I
P
A
L
--
D
--
K
E
L
--
K
A
K
G
K
S
A
L
M
F
NLQE
P
Y
F
T
W
P
L
I
A
A
D
G
G
Y
A
F
K
Y
-
E
N
G
K
Y
D
I
K
D
V
G
V
D
-------
N
A
G
A
K
A
G
L
T
F
L
V
D
L
I
K
N
K
H
M
N
A
D
T
---
D
Y
S
I
A
E
A
-
A
---
F
N
K
G
E
T
---
A
M
T
I
N
G
P
W
A
W
S
N
I
D
T
S
K
V
N
Y
-----
G
V
T
V
L
P
T
F
KGQPSK
P
F
V
G
V
L
S
A
G
I
NAASPN
K
E
L
A
K
E
F
L
E
N
Y
L
L
T
--
D
E
G
L
E
-
A
V
N
--
K
D
K
P
L
G
A
V
A
L
K
S
---
Y
E
E
E
L
AKD
P
R
I
A
A
T
M
E
N
A
Q
K
G
E
IMP
N
I
-
P
Q
M
S
A
F
W
Y
A
V
R
T
A
V
-
I
N
A
-----
A
S
--
G
R
-----------
Q
T
V
D
E
A
L
K
D
A
Q
T
N
A
----
A
A
S
N
I
N
K
A
K
V
A
S
V
E
S
D
Y
S
S
V
K
S
A
A
---
L
S
------
Y
Y
S
D
KN
T
M
P
P
S
G
E
L
D
A
L
E
T
Y
M
D
-----
T
L
P
D
KADI
G
G
G
Y
K
L
L
-
L
V
N
N
K
-
L
A
--
L
K
---
I
G
--
D
-
G
-------
T
----
A
----
A
D
S
V
T
L
-------
T
------------
K
-
A
Q
I
E
K
L
L
S
------
D
I
--
G
P
------
K
K
I
Y
T
E
N
T
L
K
T
E
L
Q
K
N
S
T
LKDG
T
L
Y
I
V
LIDN
3
PsiBlast_PDB
47.15
26%
-159
- C5 -
-
3HYI
-
?
A:
[228-292]
--------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
I
------
R
A
I
E
L
I
K
E
N
M
G
L
E
N
------
L
P
E
D
L
R
R
V
A
L
V
R
L
-
R
N
K
E
L
S
L
R
E
L
G
K
K
L
N
L
T
K
---
S
Q
I
Y
S
K
L
-
K
-
R
I
I
-
K
-
I
A
E
---
R
F
-
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
45.84
27%
-198
- C5 -
-
2QLZ
-
?
B:
[165-205]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
Q
L
A
I
L
H
Y
L
L
L
N
G
R
A
T
V
E
E
L
S
D
R
L
N
L
K
E
---
R
E
V
R
E
K
I
-
S
-
E
M
A
-
R
-
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
45.80
27%
-184
- C5 -
-
2QLZ
-
?
D:
[165-205]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
Q
L
A
I
L
H
Y
L
L
L
N
G
R
A
T
V
E
E
L
S
D
R
L
N
L
K
E
---
R
E
V
R
E
K
I
-
S
-
E
M
A
-
R
-
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
44.98
16%
33
- C4 -
-
5A5T
-
?
A:
[7-605]
RP
E
N
A
L
K
R
A
N
E
F
L
E
VG
K
K
Q
P
A
L
D
V
L
Y
D
V
M
K
S
KKHR
T
W
Q
K
I
H
E
P
I
M
L
K
Y
L
E
L
C
V
D
L
R
KSH
L
A
K
E
G
L
Y
Q
Y
K
N
I
CQQV
N
I
K
S
L
E
D
V
V
R
A
Y
L
K
L
A
E
E
K
T
E
A
A
K
E
---
E
S
Q
Q
M
V
L
D
I
E
D
L
D
N
I
Q
T
P
E
---
S
V
L
L
S
A
V
S
G
E
D
T
Q
D
R
T
D
R
L
L
L
T
P
W
V
K
F
L
W
E
-
S
Y
R
-------
Q
C
L
D
L
L
R
N
N
S
R
V
E
R
L
-
Y
H
D
I
A
Q
Q
A
F
K
F
C
L
Q
Y
T
R
K
A
E
F
R
K
L
C
D
N
L
R
M
H
L
S
Q
I
Q
---
R
H
H
N
Q
S
T
-
A
-
I
N
L
-
N
-
N
P
E
---
S
Q
-
S
M
H
L
E
--
T
--
R
L
V
--
Q
L
D
S
A
I
S
M
E
L
----
W
Q
E
A
F
K
A
V
E
D
I
H
G
L
F
S
L
S
-
K
K
P
P
K
P
Q
L
M
A
N
Y
Y
N
K
V
S
T
V
F
W
K
S
G
N
A
L
F
--
H
A
S
T
L
H
R
L
Y
H
L
S
R
E
---
M
R
K
N
L
T
Q
-
D
E
M
Q
R
M
S
T
R
V
---
L
L
A
T
L
-
S
I
P
I
T
P
E
R
T
D
I
A
R
L
L
D
MD
G
I
I
V
E
K
Q
R
R
-------
L
A
T
L
L
G
L
Q
A
--------
P
P
T
R
I
G
L
I
N
D
M
V
R
-
F
N
V
L
Q
-
Y
V
V
----
P
E
V
K
D
L
Y
N
W
L
EVE
F
N
------
P
L
K
L
C
E
R
V
T
K
V
L
N
W
V
R
-
E
Q
-
P
E
K
E
P
E
L
Q
Q
Y
V
P
Q
L
-
Q
S
N
-----
T
I
--
L
R
L
L
Q
Q
V
A
Q
I
Y
Q
S
I
E
F
S
R
L
T
S
L
V
P
F
V
D
A
F
Q
L
E
R
A
I
V
D
A
A
R
H
C
D
L
Q
V
R
I
D
H
T
S
R
T
L
---
S
F
GSDLNY
A
T
R
E
--
D
A
P
I
G
P
H
L
Q
S
M
P
S
E
Q
I
RNQ
L
T
A
M
S
S
-------
V
L
A
K
-
A
L
E
V
I
-
K
P
--
A
H
---
I
L
--
Q
-
E
-------
K
----
E
----
E
Q
H
Q
L
A
V
T
A
Y
L
K
N
S
------------
R
-
K
E
H
Q
R
I
L
A
R
R
Q
T
I
E
E
R
K
-
E
R
------
L
E
S
L
N
I
Q
R
E
K
E
E
L
E
Q
R
E
A
E
L
Q
K
V
R-------
1
PsiBlast_PDB
44.98
25%
-125
- C5 -
-
5WAY
-
?
A:
[71-169]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
S
D
I
E
M
V
-
Y
H
H
F
F
K
H
S
T
H
F
S
I
L
E
F
I
F
F
N
E
G
C
Q
A
E
S
I
C
K
E
F
Y
I
S
S
---
S
S
L
Y
R
I
I
-
S
-
Q
I
N
-
K
-
V
I
K
R
QF
Q
F
-
E
V
S
L
T
--
P
--
V
Q
I
--
I
G
N
E
R
D
I
R
Y
F
----
F
A
Q
Y
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
42.34
16%
-68
- C5 -
-
1H99
-
LICT_BACSU
A:
[72-275]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
V
S
E
E
I
I
S
Y
A
K
L
Q
L
G
K
K
L
N
D
S
I
Y
V
S
L
T
D
H
I
N
F
A
I
Q
R
N
Q
K
G
L
D
---
I
K
N
A
L
L
--
W
E
T
K
R
L
Y
K
D
E
---
F
A
I
G
K
-
E
A
L
V
M
V
K
N
K
T
G
V
S
L
-----
P
E
D
E
A
G
F
I
-------
A
L
H
I
V
N
A
E
L
--------
N
E
E
M
P
---
N
-------
I
I
N
I
T
K
V
--
M
E
E
I
L
S
-
I
V
K
Y
H
---
F
K
------
I
-
E
F
N
--
E
E
S
L
H
Y
Y
---
R
F
-
V
-
T
D
L
K
F
F
A
Q
R
L
F
N
-
G
T
H
-----
M
-ED
D
F
L
L
D
T
V
-
K
E
K
Y
-
H
R
A
Y
E
C
T
K
K
I
Q
T
Y
I
E
R
E
Y
-
E
H
K
L
T
S
D
E
L
L
Y
L
T
I
D
I
E
R
V
V
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
40.45
18%
24
- C3 -
-
4O6D
7
?
A:
[19-377]
--------------------------------------------------------------------------------------
L
Y
F
Q
S
N
A
D
T
G
C
A
I
D
---
I
S
R
Q
E
L
R
C
G
S
G
V
F
I
H
---
N
---
D
V
E
A
W
M
D
R
Y
K
Y
Y
P
E
T
P
Q
G
L
A
K
I
I
Q
K
A
H
K
E
G
----------------------------------------------------
V
C
G
L
R
S
V
S
R
L
E
---
H
Q
M
W
E
A
V
-
K
D
E
L
N
-
T
-
L
L
K
---
E
N
-
G
V
D
L
------------------------------
S
V
V
V
E
K
Q
E
G
M
Y
---
K
S
A
P
K
R
-----
L
T
A
T
A
N
N
T
F
V
V
D
G
P
E
T
K
E
C
P
---
T
Q
N
R
A
W
N
---------------------------------
S
L
E
V
E
D
F
G
--------------------------------
F
G
L
--------
T
S
T
R
M
F
L
K
V
R
E
S
N
-
T
T
E
C
D
-
S
K
I
--
I
G
T
A
V
K
N
N
L
A
I
H
---
S
-----------------
D
L
S
Y
---
W
I
E
S
R
L
N
D
T
W
K
L
E
R
A
V
L
G
E
V
K
-----
S
C
--
T
W
P
E
T
H
T
-
L
W
G
D
G
I
L
E
S
D
L
I
I
P
V
T
L
A
G
P
R
S
N
H
N
R
R
P
G
Y
K
T
Q
N
--
Q
G
P
W
D
E
G
R
V
E
I
---
D
F
------
D
Y
C
P
--
G
T
T
V
T
L
S
-
E
S
C
G
H
R
G
P
-----
A
T
R
-----------------------------
T
--
T
-
T
-------
E
----
S
----
G
K
---
L
I
T
D
W
C
C
R
S
----------------
C
T
L
P
P
L
------
R
Y
Q
-
T
D
S
G
C
W
Y
G
M
E
I
R
P
Q
R
H
D
E
K
T
L
V
Q
S
Q
V
NA-----------
2
PsiBlast_PDB
39.53
22%
-49
- C5 -
-
4R6I
-
ATXA_BACAN
A:
[112-246]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
Q
K
L
H
L
Q
V
---
G
A
L
Y
P
I
I
-
N
-
Q
I
N
-
Y
-
D
I
Q
---
S
S
-
H
L
N
I
K
--
K
--
K
P
L
E
I
S
G
R
E
Q
D
V
R
V
F
----
M
L
R
L
Y
C
N
I
P
N
D
Y
W
P
F
P
Y
I
-
N
K
Q
N
I
T
D
L
I
N
K
M
E
K
I
L
N
V
Q
M
Y
T
Y
S
K
H
K
L
C
V
L
F
A
I
T
I
S
R
L
L
-
S
G
N
---
T
I
D
N
V
S
G
-
L
I
L
V
N
K
N
D
D
H
---
Y
K
T
V
A
-
S
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
35.81
11%
-24
- C5 -
-
4MGE
-
?
B:
[1-102]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
I
L
L
C
C
S
A
G
M
S
T
S
L
-----
L
V
T
--------
K
M
E
A
-
A
A
K
A
R
G
L
E
GK
I
W
---
A
V
--
S
-
G
-------
D
----
A
VKTN
I
D
Q
A
D
V
L
L
L
G
P
Q
V
R
YMLSSMKTLADE
R
-
N
V
G
I
D
V
I
N
------
P
M
H
Y
G
M
------
M
N
G
E
A
V
L
D
H
A
L
T
L
K
K
G
E
--------------
34
Fugue
35.64
15%
-120
* C5 *
-
1BIA
-
?
?:
[1-88]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
D
N
T
V
P
L
K
L
I
A
L
L
A
N
G
E
F
H
S
G
E
Q
L
G
E
T
L
G
M
S
R
---
A
A
I
N
K
H
I
-
Q
-
T
L
R
-
D
-
W
--------
G
V
D
V
F
--
T
--
V
P
G
--
K
G
Y
S
L
P
E
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
35.52
11%
-17
- C5 -
-
4MGE
1
?
A:
[1-102]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
I
L
L
C
C
S
A
G
M
S
T
S
L
-----
L
V
T
--------
K
M
E
A
-
A
A
K
A
R
G
L
E
G
K
I
W
---
A
V
--
S
-
G
-------
D
----
A
VKTN
I
D
Q
A
D
V
L
L
L
G
P
Q
V
R
YM
L
S
S
M
K
T
L
A
D
E
R
-
N
V
G
I
D
V
I
N
------
P
M
H
Y
G
M
------
M
N
G
E
A
V
L
D
H
A
L
T
L
K
K
G
E
--------------
31
Fugue
32.26
11%
-7
- C6 -
-
3TEL
4
?
A:
[14-385]
--------------------------------------------------------------------------------------------
S
E
Y
S
L
S
V
A
---
V
L
A
D
----
S
E
I
E
N
V
T
Q
L
T
S
---
V
T
A
P
T
G
T
D
N
E
N
I
Q
K
L
L
A
D
I
K
S
S
Q
N
T
D
L
T
V
N
-
Q
S
S
-----------------
S
Y
L
A
A
-
Y
K
S
L
I
A
G
E
T
K
------------------
A
I
V
L
N
S
V
F
---
E
N
I
I
E
L
E
-
Y
-
P
------------------------------
D
Y
A
S
K
I
K
K
I
----
Y
T
K
G
F
T
K
K
V
E
A
P
K
T
---
S
-
K
N
Q
S
F
N
I
Y
V
S
G
I
D
T
Y
G
P
I
S
S
V
S
R
S
D
V
N
I
L
M
T
V
N
R
D
T
K
K
I
L
L
T
T
T
P
AD
A
Y
V
P
I
---------
A
D
G
G
---
N
N
Q
K
D
-
K
L
T
H
A
G
I
Y
G
V
D
S
S
I
-----
H
T
L
E
N
L
Y
G
-------
V
D
I
-----------------
N
Y
Y
V
R
L
N
F
T
S
-
F
L
K
M
I
-
D
L
L
G
G
V
D
V
H
N
D
Q
E
F
S
A
L
---
H
G
------
K
F
H
F
P
V
G
N
V
H
L
D
S
E
---
Q
A
-
L
G
F
V
R
E
R
Y
S
L
A
D
G
-----------
D
--
R
D
R
G
R
N
Q
-
Q
K
V
I
V
A
I
L
Q
K
L
T
---
S
T
E
A
L
K
N
Y
S
T
I
I
N
S
L
Q
D
S
I
Q
T
N
V
P
L
E
T
M
I
N
L
V
---
N
A
------
Q
L
E
S
--
G
-------
G
N
Y
K
V
N
S
Q
-----
D
----------------
L
K
G
T
-
G
R
--
M
D
---
L
P
--
S
-
Y
-------
A
----
M
----
P
D
S
N
L
Y
V
M
E
I
------------------------------------
D
D
------
S
S
L
A
V
V
K
A
A
I
Q
D
V
M
E
G
R
--------------
12
HHSearch
32.07
14%
10
- C5 -
-
2FEW
-
?
B:
[376-471]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
--
V
R
K
I
I
V
A
S
D
A
G
M
G
S
S
A
-----
M
G
A
G
-------
V
L
R
K
-
K
I
Q
D
A
--
G
--
L
S
QIS
V
T
NS
A
-
I
-------
N
----
N
L---
P
P
D
V
D
L
V
I
T
H
R
D
L
T
ERAMRQV-----
P
-
Q
A
Q
H
I
S
L
T
------
N
F
L
-
D
S
------
G
L
Y
T
S
L
T
E
R
L
V
A
A
Q
R
H
---------------
33
Fugue
31.25
11%
-133
- C- -
-
2UVK
-
NANM_ECOLI
A:
[1-349]
------------------------------------------------------------------------------------
S
V
L
P
E
T
P
V
P
F
K
S
G
T
G
A
---
I
D
------
N
D
T
V
Y
I
G
L
G
S
A
---
G
T
A
W
Y
K
L
D
T
Q
A
K
D
K
K
W
T
A
L
A
A
F
P
G
G
P
-----
R
D
Q
A
------
T
S
A
F
I
D
G
---------
N
L
Y
V
F
G
G
I
G
K
N
-------
S
E
G
L
T
Q
V
F
N
D
V
H
K
Y
N
-
P
K
---
T
N
S
W
V
K
L
M
S
-
H
A
P
M
G
M
A
-----
G
H
-
V
T
F
V
H
--
N
--
G
K
A
--
Y
V
T
G
---------------------------------------
G
V
N
Q
N
I
F
N
G
Y
F
E
D
L
N
E
A
G
K
D
S
T
A
I
D
K
I
N
A
H
Y
F
D
K
---
K
A
E
D
Y
F
F
-
N
K
F
L
L
S
F
D
P
S
---
T
Q
Q
W
S
-
Y
A
G
E
S
P
W
Y
G
T
A
G
--------------------------
A
A
V
V
N
--------
K
G
D
K
T
W
L
I
N
G
E
A
K
-
P
G
L
R
T
-
D
----
A
V
F
E
L
D
F
T
L
K
W
N
---
K
L
------
A
P
--
V
S
S
P
D
G
V
A
G
G
---
F
A
-
G
I
S
N
D
-
S
L
I
F
A
G
G
A
-
G
-----------------------
F
K
G
S
R
E
N
Y
Q
N
G
K
N
Y
A
H
E
G
L
K
K
S
Y
S
T
D
I
H
L
W
H
W
---------------------------------
D
K
S
G
E
L
S
Q
G
R
A
-----
Y
G
V
S
-------
L
P
W
N
N
S
L
L
I
I
-
G
G
--
E
T
---
A
G
--
G
-
K
-------
A
----
V
----
T
D
S
V
L
I
T
V
--------------------------------------------------------
D
N
K
V
T
V
Q
N
-------------
11
HHSearch
30.74
12%
-38
- C5 -
-
1TVM
-
PTKB_ECOL6
A:
[19-112]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
--
K
R
K
I
I
V
A
C
G
G
A
V
A
T
S
T
-----
M
A
A
E
-------
E
I
K
E
-
L
C
Q
S
H
--
N
--
I
P
V
E
-
L
I
Q
C
R
-
V
-------
N
EIET
Y
----
M
D
G
V
H
L
I
C
T
T
A
R
V
D
RS----------
F
G
D
I
P
L
V
H
G
M
------
P
F
V
-
S
G
------
V
G
I
E
A
L
Q
N
K
I
L
T
I
L
Q
----------------