@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : I3U021: (2017-12-17 )
MALAESEEEFFMGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDDKRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNGTLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLRAHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRISYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLGDPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQQAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIVDLSNGIPKFCPNCGKPFKGIPVN
Atome Classification :
(20 SA)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20.....-..----.30........40........50........60..----......70........--80........90........100..--------..-...110...--.------------------...120..---------.....130-----.......140-....--------...150..--------------------------.....160.-......170.------......180...------------....190.......200.......210.-------......220.......230.......240.......250.....-..260...-....270..----.....280...--....-290...---------....300....------------...------310.......320........330.......340..------------------------------.....350--.........360.......370----..--.....380.......390.......-400-.-.....------.---..----410---------.----........420....-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALAE
S
E
E
E
F
F
M
G
L
I
K
A
A
T
S
MVGG
G
L
-
A
D
----
Q
W
L
E
V
IEPDNMSD
T
T
V
M
TKG
V
K
V
RKDDKRGSNRKG----TEDVLTDG
T
V
V
H
VYP
N
--
M
M
M
L
L
VDGG
K
I
I
D
Y
TAEE
G
Y
Y
T
IKN--------DA-A
P
S
M
F
N
G
T
L
--
K
------------------
E
A
I
A
E
T
F
D
---------
R
FKFGGVT-----PQ
K
Q
Q
V
F
Y
I
N
-
L
Q
EI--------KGIKFGTS--------------------------A
P
L
N
Y
F
D
N
F-YN
A
E
L
F
L
R
AH------G
T
Y
S
I
H
VV
D
P
I
L
------------
F
YTNAIPKNK
T
Q
V
E
INDI
N
E
Q
Y
L
A
E
F
L
T
-------
A
L
Q
S
A
I
N
Q
MSADG
Q
R
I
S
YVPSKSL
E
L
S
K
Y
M
D
T
AL
D
D
S
W
R
E
LRG
M
-
E
I
V
S
V
A
V
A
-
S
I
SYTDD
S
V
----
K
L
I
N
MRNEGAM--LGD
P
-
S
V
RE
G
Y
---------
V
Q
G
S
I
A
R
G
M
E
A------------AGK------NEAGAMTGF
M
G
-VGMGMNA
N
G
S
Y
L
S
Q
A
AQN
N
Q
E
Q
I
K
------------------------------
Q
Q
A
E
KQ----NQQTAQGNAD
T
W
TCPVCGTENS----GK--
F
C
SNCGAAK
P
V
E
NV
Q
P
K
L
Q
M
R
C
S
E
C
-
N
---
E
-
I
V
D
LS------N---G
I
----
P
-----------
K
----FCPNCGKPFKGIPVN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
Fugue
61.85
16%
12
- C3 -
-
5AKP
2
BPHY_XANC8
B:
[18-638]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VCAREPIHIPGLIQPY
G
V
L
L
V
I
D
P
A
D
G
R
I
V
Q
A
S
T
T
A
A
D
L
L
G
V
P
M
-
A
A
LLGM
P
Y
T
Q
V
L
T
L
P
E
A
Q
P
F
A
V
D
D
Q
P
Q
H
L
M
H
A
E
V
R
F
P
Q
R
A
-----
T
P
P
A
S
A
W
V
A
A
W
H
L
Y
P
Q
Q
W
L
V
E
M
E
P
R
D
A
R
L
L
D
V
T
L
R
E
A
M
P
L
L
R
S
V
E
R
DPG
I
A
E
A
-
A
V
R
V
A
K
G
L
R
--
S
L
IGFD
R
V
M
I
Y
R
F
D
EEWNG
D
I
I
A
E
A
R
K
PELEAYLG
L
H
Y
P
A
S
D
I
P
-----
A
Q
A
R
A
L
Y
L
R
N
R
V
R
Q
I
--------
A
D
V
G
Y
Q
P
S
PIQPTVHPQLGTPVDLSDVSLRSVS
P
V
H
L
E
Y
L
A
N
M
G
V
T
A
T
L
V
A
S
I
V
VNDALW
G
L
I
S
C
H
H
Y
S
P
--------------
H
F
T
N
H
A
M
R
D
V
T
D
A
V
A
R
T
L
A
G
R
I
G
A
L
Q
A
V
-------
A
R
A
R
L
E
S
V
L
L
T
V
R
E
K
L
I
T
D
F
N
D
A
E
H
M
T
V
E
L
L
D
D
M
A
P
D
L
M
D
V
V
D
A
-
D
G
V
A
I
F
H
G
N
D
I
S
R
H
G
T
T
P
----
D
V
A
A
L
R
R
I
R
D
H
--
I
E
S
E
-
H
H
E
A
L
R
---------
E
D
A
V
G
A
L
H
V
D
A
------------
I
G
E
VFPELA
D
L
A
P
L
A
A
G
F
I
F
-
V
P
L
-
M
P
Q
S
R
S
A
L
L
W
T
R
R
E
Q
I
Q
Q
I
K
W
AGNP-------------------------
R
K
S
F
D
L
----
W
Q
Q
T
V
R
G
R
A
R
R
W
S
P
L
H
L
E
S
A
R
S
----
L
R
--
V
L
I
E
L
M
E
R
K
R
F
Q
Q
D
F
T
L
L
E
A
S
L
S
R
L
-
R
---
D
G
V
A
I
I
E
------
R
---
G
T
----
A
NAAHRLLFVN
T
A
----
F
A
D
V
C
G
S
D
V
A
E
L
I
G
R
E
L
Q
T
L
Y
ASDAP
R
A
N
V
E
L
L
Q
D
A
L
R
N
G
R
A
A
Y
V
T
L
P
L
QVSDGA
P
V
Y
R
Q
F
H
L
E
P
L
P
SPSGVTA
H
W
L
L
Q
L
R
D----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
54.08
15%
-130
- C7 -
-
4FVF
-
STOM_MOUSE
B:
[4-120]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
S
L
I
K
V
D
-
M
R
T
I
--------
S
F
-
D
I
P
-
P
--------------------------
Q
E
V
--
L
T
K
D
----
S
V
T
I
S
V
D
------
G
V
V
Y
Y
R
V
Q
N
A
T
L
------------
A
V
A
N
-
I
T
---------
N
A
D
S
A
T
R
L
L
A
Q
T
-------
T
L
R
N
A
L
G
T
K
-----
N
L
S
Q
I
L
S
D
R
E
E
I
A
H
H
M
Q
S
T
L
D
D
A
T
D
-
D
W
G
I
-
K
V
E
R
V
E
I
K
-
D
V
K
L
P
V
Q
L
Q
----
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
53.49
18%
-170
- C7 -
-
2RPB
-
?
A:
[63-174]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
D
H
V
D
-
L
R
E
H
--------
V
I
-
D
V
P
-
P
--------------------------
Q
E
V
I
C
K
D
------
N
V
V
V
T
V
D
------
A
V
V
Y
Y
Q
V
I
D
P
V
K
------------
A
V
Y
N
V
-
S
---------
D
F
L
M
A
I
V
K
L
A
Q
T
-------
N
L
R
A
I
I
G
E
M
-----
E
L
D
E
T
L
S
G
R
D
I
I
N
A
R
L
R
E
E
L
D
K
I
T
D
-
R
W
G
V
-
K
I
T
R
V
E
I
Q
-
R
I
D
P
P
K
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
Fugue
52.36
21%
33
- C2 -
-
5IJL
-
DP2L_PYRAB
A:
[9-1044]
P
K
E
M
E
E
Y
F
E
M
L
Q
R
E
I
D
K
A
Y
E
I
A
K
K
A
R
A
Q
GKDPSLDVE
I
P
Q
A
TD
M
A
G
R
V
E
S
L
VGPPG
V
A
K
R
I
R
E
L
V
K
E
YG
K
E
I
A
A
L
K
I
V
D
E
I
I
E
GKFGDLGS
R
E
K
Y
A
E
Q
A
V
R
T
A
L
A
I
L
T
EGIVSAPIEGIA
N
V
K
I
K
R
NTWADN
S
E
Y
L
A
L
Y
Y
A
GPIRSSG
G
T
A
Q
A
L
S
V
L
V
G
D
Y
V
R
R
K
L
GLD
R
F
K
P
S
E
K
H
I
E
R
M
V
E
E
V
D
L
Y
H
R
AVTRLQ
Y
H
P
S
P
E
E
V
R
L
A
M
R
N
IPIEITGEATDDVEVSHRDVPGVETNQLR
G
G
A
I
L
V
L
AEGVLQK
A
K
K
L
V
K
Y
I
D
K
M
G
I
E
G
W
E
W
L
K
E
F
V
E
A
K
E
K
G
V
D
M
G
F
-
Y
Y
----
S
L
Y
Q
K
F
K
E
E
P
L
F
S
D
P
S
K
P
G
G
F
R
L
R
Y
G
R
S
W
G
I
N
----------------------
P
--
A
T
M
I
L
V
G
A
V
V
T
P
V
T
T
I
E
G
P
I
V
K
L
K
D
--------
G
S
-
V
L
R
V
D
D
Y
N
L
--
A
------------------
L
K
V
R
E
D
--------------------------
V
E
E
I
L
Y
L
G
-
D
A
V
I
--------
A
-
F
G
D
Q
T
L
--------------------------
L
P
A
N
Y
C
E
E
W
-
W
I
L
E
F
V
K
A
L
K
------
E
I
Y
E
V
H
L
-
E
P
--------------
F
T
E
N
E
E
E
S
I
E
E
A
S
D
Y
L
E
I
D
P
E
F
L
K
E
M
L
R
DPLRVKP
P
V
E
L
A
I
H
F
S
E
V
L
G
--
I
P
L
H
P
Y
Y
T
L
Y
W
N
S
V
E
P
K
D
V
E
K
L
W
R
L
L
K
N
Y
A
E
I
E
W
S
N
F
R
-
G
I
K
F
A
K
K
I
V
I
S
QE
K
L
G
D
S
K
R
T
L
E
L
--
L
G
L
P
H
T
V
R
D
G
N
---------
V
I
V
D
---------------------
Y
------
P
W
A
A
A
L
L
T
P
L
G
N
L
N
W
E
F
M
A
K
P
L
Y
A
T
I
D
I
I
N
E
N
N
E
I
K
L
R
DRGISWIGKPPVQVLFPIGLAGGSSRD
I
K
K
A
A
E
E
----
G
K
-
V
A
E
V
E
I
A
F
F
K
C
P
K
C
G
H
V
G
P
----
E
H
--
L
C
P
N
C
G
T
R
K
E
L
L
W
V
C
P
R
C
N
A
E
Y
P
----------
E
S
Q
A
------
E
---
G
Y
----
N
-----------
Y
----
T
C
P
K
C
N
V
K
L
R
P
Y
A
K
R
K
I
R
P
S
E
L
L
N
R
A
M
E
N
V
KVYGVD
K
L
K
G
V
MGMTSGWKMPEP
L
E
K
G
L
L
R
A
K
N
D
V
Y
V
F
KDG
T
I
R
F
D
A
T
D
A
P
I
THFRPREIGVS
V
E
K
L
R
E
L
GYTHDFEGKPLVSED
Q
I
V
E
L
K
PQ
D
I
I
L
S
K
E
A
G
R
Y
L
L
K
V
A
K
F
V
D
D
L
L
E
KFYG
L
P
R
F
YNAEKMEDLIG
H
L
V
I
G
L
A
P
HTS
A
G
I
V
G
R
I
IGFVDAL
V
G
Y
A
H
PYFHA
A
K
R
R
N
C
DGD
E
D
A
V
M
L
L
L
D
A
L
L
NFSRYYLPEKRGGKMDAPL
V
I
T
TRLDPRYYP
L
E
F
Y
E
A
T
Y
E
LKS
P
K
E
L
V
G
V
I
E
R
V
E
D
19
HHSearch
51.40
15%
-134
- C7 -
-
4FVG
-
STOM_MOUSE
A:
[14-122]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
-
M
R
T
I
--------
S
F
-
D
I
P
-----------------------------
P
Q
E
V
L
T
K
D
----
S
V
T
I
S
V
D
------
G
V
V
Y
Y
R
V
Q
N
A
T
L
------------
A
V
A
N
I
-
T
---------
N
A
D
S
A
T
R
L
L
A
Q
T
-------
T
L
R
N
A
L
G
T
K
-----
N
L
S
Q
I
L
S
D
R
E
E
I
A
H
H
M
Q
S
T
L
D
D
A
T
D
-
D
W
G
I
-
K
V
E
R
V
E
I
K
-
D
V
K
L
P
V
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
51.38
12%
-149
* C7 *
-
1WIN
-
FLOT2_MOUSE
A:
[3-135]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
G
S
-
S
G
Q
R
I
S
-
L
E
I
M
--------
T
L
-
Q
P
R
-----------------------------
C
E
D
V
E
T
A
E
----
G
V
A
L
T
V
T
------
G
V
A
Q
V
K
I
M
T
E
K
E
------------
L
L
A
V
A
C
E
Q
F
L
-
G
K
N
V
Q
D
I
K
N
V
V
L
Q
T
L
E
G
-------
H
L
R
S
I
L
G
T
L
-----
T
V
E
Q
I
Y
Q
D
R
D
Q
F
A
K
L
V
R
E
V
A
A
P
D
V
G
-
R
M
G
I
-
E
I
L
S
F
T
I
K
-
D
V
Y
D
K
V
D
Y
L
----
S
S
L
G
K
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
50.95
14%
-150
- C7 -
-
3BK6
-
PSTOM_PYRHO
A:
[55-179]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
F
E
K
A
V
I
V
D
-
L
R
T
Q
--------
V
L
-
D
V
P
-----------------------------
V
Q
E
T
I
T
K
D
----
N
V
P
V
R
V
N
------
A
V
V
Y
F
R
V
V
D
P
V
K
------------
A
V
T
Q
V
-
K
N
---------
Y
I
M
A
T
S
Q
I
S
Q
T
-------
T
L
R
S
V
I
G
Q
A
-----
H
L
D
E
L
L
S
E
R
D
K
L
N
M
Q
L
Q
R
I
I
D
E
A
T
D
-
P
W
G
I
-
K
V
T
A
V
E
I
K
-
D
V
E
L
P
A
G
M
Q
----
K
A
M
A
R
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
49.96
14%
-138
- C7 -
-
3BK6
-
PSTOM_PYRHO
C:
[55-179]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
F
E
K
A
V
I
V
D
-
L
R
T
Q
--------
V
L
-
D
V
P
-----------------------------
V
Q
E
T
I
T
K
D
----
N
V
P
V
R
V
N
------
A
V
V
Y
F
R
V
V
D
P
V
K
------------
A
V
T
Q
V
-
K
N
---------
Y
I
M
A
T
S
Q
I
S
Q
T
-------
T
L
R
S
V
I
G
Q
A
-----
H
L
D
E
L
L
S
E
R
D
K
L
N
M
Q
L
Q
R
I
I
D
E
A
T
D
-
P
W
G
I
-
K
V
T
A
V
E
I
K
-
D
V
E
L
P
A
G
M
Q
----
K
A
M
A
R
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
Fugue
48.47
13%
59
- C4 -
-
4LLG
-
RPOD_ECOLI
F:
[6-612]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QS
Q
L
K
L
L
V
T
R
G
K
E
Q
G
Y
L
T
Y
A
E
V
N
D
H
L
P
E
D
I
V
D
S
D
----
Q
I
E
D
I
I
Q
M
I
N
D
M
G
I
Q
V
M
G
R
T
T
D
P
V
R
M
Y
M
R
E
M
G
T
V
E
L
L
T
R
E
G
E
I
D
I
A
K
R
I
E
D
G
I
N
Q
--
V
Q
C
S
V
A
E
Y
P
E
A
I
T
Y
L
L
E
Q
Y
D
R
V
E
A
E
--------
E
A
R
L
S
D
L
I
T
G
F
V
DD
P
------------------
E
L
A
R
E
K
F
A
---------
E
L
R
A
Q
Y
V
V
T
R
D
TI
K
A
T
A
Q
E
E
I
L
K
-
L
S
E
V
F
K
Q
FRLV
P
K
Q
F
D
Y
L
V
N
--------------------------
S
M
R
V
M
M
D
R
V
-
R
T
Q
E
R
L
I
M
K
L
------
C
V
E
Q
C
K
M
P
K
K
N
F
I
TLFTGNETSDT
W
F
N
A
A
I
A
M
N
K
P
W
S
E
K
L
H
D
V
S
E
E
V
H
R
A
L
Q
-------
K
L
Q
Q
I
E
E
E
T
G
L
T
I
E
Q
V
K
D
I
-
N
R
R
M
S
I
G
E
A
K
A
R
R
A
K
K
E
M
V
E
A
N
L
R
-
L
V
I
S
I
A
K
K
-
Y
T
N
R
G
L
Q
F
L
----
D
L
I
Q
E
G
N
I
G
L
M
K
A
V
D
K
F
-
E
Y
R
R
G
Y
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
T
R
S
I
A
D
QART
I
R
I
P
V
H
M
I
E
T
I
------
N
K
L
N
R
I
S
R
Q
M
L
-
Q
E
M
G
R
E
P
T
P
E
E
L
A
E
R
M
L
M
P
E
D
K
I
R
------------------------------
K
V
L
K
I
A
KEPI
S
M
E
T
P
I
G
D
D
E
D
S
H
L
G
D
F
I
E
D
T
T
----
L
E
--
L
P
L
D
S
A
T
T
E
S
L
R
A
A
T
H
D
V
L
A
G
L
T
A
R
E
A
---
K
-
V
L
R
M
R
------
F
---
G
I
DMNT
D
-----------
Y
----
T
L
E
E
V
G
K
Q
F
D
V
T
R
E
R
I
R
Q
I
E
A
K
A
L
R
K
L
RHP
S
R
S
E
V
L
RSFLD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
41.42
27%
-161
- C5 -
-
4MVT
-
PIAS3_HUMAN
A:
[270-314]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
W
T
C
P
V
C
D
K
K
A
P
----
Y
E
---------
S
L
I
I
D
G
L
F
M
E
I
L
S
S
C
S
D
C
-
D
---
E
-
I
Q
F
M
E
------
D
---
G
-----------------
S
----
W
C
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
37.17
26%
-55
- C5 -
-
2E6S
-
A:
[5-74]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
G
R
N
D
T
-
E
C
D
L
C
G
G
D
P
E
----
K
K
---
C
H
S
C
S
C
R
V
C
G
G
K
H
E
P
N
M
Q
L
L
C
D
E
C
-
N
---
V
-
A
Y
H
I
Y
CLNPPL
D
---
K
V
----
P
-----------
E
E
E
Y
W
Y
C
P
S
C
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
34.18
28%
-76
- C5 -
-
4TVR
-
UHRF2_HUMAN
A:
[216-277]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
D
L
C
G
G
D
P
E
----
K
K
---
C
H
S
C
S
C
R
V
C
G
G
K
H
E
P
N
M
Q
L
L
C
D
E
C
-
N
V
A
Y
H
-
I
Y
C
L
N
------
P
---
P
L
----
D
-----------
K
VW--
Y
C
P
S
C
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
32.49
25%
-50
- C5 -
-
3GJ8
-
D:
[65-90]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
W
D
C
E
V
C
-
L
---
V
-
Q
N
K
A
------------
D
----
S
-----------
T
----
K
C
I
A
C
E
S
A
K
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
32.45
25%
-32
- C5 -
-
2JRP
-
?
A:
[3-66]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
C
P
V
C
H
H
A
L
E
R
NGD
T
A
--
H
C
E
T
C
A
K
D
F
S
L
-------
Q
A
L
C
P
D
C
-
R
---
Q
-
P
L
Q
V
L
------
K
A
CG
A
V
----
D
-----------
Y
----
F
C
Q
N
G
H
G
L
I
S
K
K
R
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
31.99
27%
39
- C5 -
-
5IJL
-
DP2L_PYRAB
A:
[685-771]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
G
S
S
R
D
I
K
------------------------------
K
A
A
E
E
G
------
K
V
A
E
V
E
I
A
F
F
K
C
P
K
C
G
H
V
G
P
----
E
H
--
L
C
P
N
C
G
T
R
K
E
L
L
W
V
C
P
R
C
N
A
E
Y
P
E
S
-
Q
---------
A
------
E
---
G
Y
----
N
-----------
Y
----
T
C
P
K
C
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
30.96
55%
-18
- C1 -
-
3PWF
-
?
B:
[153-163]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
-----------
E
----
Y
C
P
V
C
G
A
P
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
30.76
23%
-31
- C5 -
-
3GJ7
-
NU153_RAT
B:
[71-96]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
T
W
D
C
D
T
C
-
L
---
V
-
Q
N
K
P
------------
E
----
A
-----------
V
----
K
C
V
A
C
E
T
P
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
HHSearch
29.61
22%
-75
- C5 -
-
2LK1
1
A:
[6-28]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
L
C
N
K
C
-
C
---
L
-
N
N
F
R
------------
K
----
R
-----------
L
----
K
C
F
R
C
G
A
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
Fugue
28.77
29%
-17
- C5 -
-
4OWF
-
G:
[2-30]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
G
R
W
A
C
Q
S
C
T
F
E
N
E
----
A
A
AV
L
C
S
I
C
E
R
P
R
L
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
28.55
27%
-28
- C5 -
-
5IJL
-
DP2L_PYRAB
A:
[711-756]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
P
K
C
G
H
V
G
P
--------
E
H
L
C
P
N
C
-
G
---
T
-
R
K
E
-------------
L
----
L
-----------
W
----
V
C
P
R
C
N
A
E
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------