@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3XYF2: (2018-01-08 )
MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQEGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAAMRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLDGVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGRPITQSTNPYKAYQTIQTEWS
Atome Classification :
(23 SA)
.........10........20...-.....-30........40......----..50......-..60........70........-80........90........100......----.---110.......120.......130.......140.......150---........160.......170.......180.......190........200.......210.......220.-......230......--
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MNQLDQR
P
I
I
A
L
DFS
T
R
Q
E
V
E
D
F
L
-
R
FFPK-EEK
L
F
V
K
I
G
M
E
L
F
YQEG
P
----
E
I
V
R
Y
L
K
EAG-
H
N
V
F
L
D
L
K
LHDI
P
N
T
V
E
K
A
M
R
G
-
L
A
KLGV
D
L
T
C
V
HAAG
G
I
R
M
M
E
A
A
M
R
G
L
EE----G---TPEGGKR
P
L
L
L
A
I
TQLTST
S
E
E
E
M
H
A
D
Q
L
I
E
V
S
L
E
K
S
V
I
H
Y
A
----
S
C
A
K
KAGL
D
G
V
V
SS
A
W
E
V
E
A
I
K
E
MAGD
E
F
V
C
LTPGIRPE-GTVAGDQ
T
R
V
VT
P
S
Q
A
KKIG
S
T
F
I
V
I
GRPITQS-TNPY
K
A
Y
Q
T
I
QTEWS--
35
HHSearch
90.91
57%
-131
- C3 -
-
2YYU
2
PYRF_GEOKA
B:
[4-235]
----
H
T
P
F
I
V
A
L
D
F
P
S
K
Q
E
V
E
R
F
L
-
R
P
F
-
A
-
G
T
P
L
F
V
K
V
G
M
E
L
Y
Y
Q
E
G
P
----
A
I
V
A
F
L
K
E
Q
G
-
H
A
V
F
L
D
L
K
L
H
D
I
P
N
T
V
K
Q
A
M
K
G
-
L
A
R
V
G
A
D
L
V
N
V
H
A
A
G
G
R
R
M
M
E
A
A
I
E
G
L
D
A
----
G
---
T
P
S
G
R
M
R
P
R
C
I
A
V
T
Q
L
T
S
T
D
E
R
M
L
H
E
E
L
W
I
S
R
P
L
V
E
T
V
A
H
Y
A
----
A
L
A
K
E
S
G
L
D
G
V
V
C
S
A
N
E
A
A
F
I
K
E
R
C
G
A
S
F
L
A
V
T
P
G
I
R
F
A
-
D
D
A
A
----
R
V
V
T
P
R
K
A
R
A
L
G
S
D
Y
I
V
I
G
R
S
L
T
R
A
-
A
D
P
L
R
T
Y
A
R
L
Q
H
E
W
---
21
PsiBlast_CBE
89.51
57%
-132
- C3 -
-
2YYU
2
PYRF_GEOKA
B:
[8-236]
--------
I
V
A
L
D
F
P
S
K
Q
E
V
E
R
F
L
-
R
P
F
A
G
-
T
-
P
L
F
V
K
V
G
M
E
L
Y
Y
Q
E
G
P
----
A
I
V
A
F
L
K
E
Q
G
-
H
A
V
F
L
D
L
K
L
H
D
I
P
N
T
V
K
Q
A
M
K
G
-
L
A
R
V
G
A
D
L
V
N
V
H
A
A
G
G
R
R
M
M
E
A
A
I
E
G
L
D
A
----
G
---
T
P
S
G
R
M
R
P
R
C
I
A
V
T
Q
L
T
S
T
D
E
R
M
L
H
E
E
L
W
I
S
R
P
L
V
E
T
V
A
H
Y
A
----
A
L
A
K
E
S
G
L
D
G
V
V
C
S
A
N
E
A
A
F
I
K
E
R
C
G
A
S
F
L
A
V
T
P
G
I
R
F
A
-
D
D
A
A
----
R
V
V
T
P
R
K
A
R
A
L
G
S
D
Y
I
V
I
G
R
S
L
T
R
A
-
A
D
P
L
R
T
Y
A
R
L
Q
H
E
W
N
--
51
Fugue
89.10
56%
-107
- C3 -
-
1DBT
2
PYRF_BACSU
A:
[1-237]
--
M
K
N
N
L
P
I
I
A
L
D
F
A
S
A
E
E
T
L
A
F
L
-
A
P
F
Q
Q
-
E
-
P
L
F
V
K
V
G
M
E
L
F
Y
Q
E
G
P
----
S
I
V
K
Q
L
K
E
R
N
-
C
E
L
F
L
D
L
K
L
H
D
I
P
T
T
V
N
K
A
M
K
R
-
L
A
S
L
G
V
D
L
V
N
V
H
A
A
G
G
K
K
M
M
Q
A
A
L
E
G
L
E
E
----
G
---
T
P
A
G
K
K
R
P
S
L
I
A
V
T
Q
L
T
S
T
S
E
Q
I
M
K
D
E
L
L
I
E
K
S
L
I
D
T
V
V
H
Y
S
----
K
Q
A
E
E
S
G
L
D
G
V
V
C
S
V
H
E
A
K
A
I
Y
Q
A
V
S
P
S
F
L
T
V
T
P
G
I
R
M
S
-
E
D
A
A
N
D
Q
V
R
V
A
T
P
A
I
A
R
E
K
G
S
S
A
I
V
V
G
R
S
I
T
K
A
-
E
D
P
V
K
A
Y
K
A
V
R
L
E
W
E
GI
2
PsiBlast_PDB
88.78
57%
-129
- C3 -
-
2YYU
2
PYRF_GEOKA
A:
[8-236]
--------
I
V
A
L
D
F
P
S
K
Q
E
V
E
R
F
L
-
R
P
F
A
G
-
T
-
P
L
F
V
K
V
G
M
E
L
Y
Y
Q
E
G
P
----
A
I
V
A
F
L
K
E
Q
G
-
H
A
V
F
L
D
L
K
L
H
D
I
P
N
T
V
K
Q
A
M
K
G
-
L
A
R
V
G
A
D
L
V
N
V
H
A
A
G
G
R
R
M
M
E
A
A
I
E
G
L
D
A
----
G
---
T
P
S
G
R
M
R
P
R
C
I
A
V
T
Q
L
T
S
T
D
E
R
M
L
H
E
E
L
W
I
S
R
P
L
V
E
T
V
A
H
Y
A
----
A
L
A
K
E
S
G
L
D
G
V
V
C
S
A
N
E
A
A
F
I
K
E
R
C
G
A
S
F
L
A
V
T
P
G
I
R
F
A
-
D
-------
R
V
V
T
P
R
K
A
R
A
L
G
S
D
Y
I
V
I
G
R
S
L
T
R
A
-
A
D
P
L
R
T
Y
A
R
L
Q
H
E
W
N
--
3
PsiBlast_PDB
88.10
56%
-110
- C3 -
-
1DBT
2
PYRF_BACSU
A:
[3-234]
----
N
N
L
P
I
I
A
L
D
F
A
S
A
E
E
T
L
A
F
L
-
A
P
F
-
Q
-
Q
E
P
L
F
V
K
V
G
M
E
L
F
Y
Q
E
G
P
----
S
I
V
K
Q
L
K
E
R
N
-
C
E
L
F
L
D
L
K
L
H
D
I
P
T
T
V
N
K
A
M
K
R
-
L
A
S
L
G
V
D
L
V
N
V
H
A
A
G
G
K
K
M
M
Q
A
A
L
E
G
L
E
E
----
G
---
T
P
A
G
K
K
R
P
S
L
I
A
V
T
Q
L
T
S
T
S
E
Q
I
M
K
D
E
L
L
I
E
K
S
L
I
D
T
V
V
H
Y
S
----
K
Q
A
E
E
S
G
L
D
G
V
V
C
S
V
H
E
A
K
A
I
Y
Q
A
V
S
P
S
F
L
T
V
T
P
G
I
R
M
S
-
E
D
A
A
N
D
Q
V
R
V
A
T
P
A
I
A
R
E
K
G
S
S
A
I
V
V
G
R
S
I
T
K
A
-
E
D
P
V
K
A
Y
K
A
V
R
L
E
W
---
1
PsiBlast_PDB
87.38
57%
-148
- C3 -
-
2YYT
-
PYRF_GEOKA
A:
[8-236]
--------
I
V
A
L
D
F
P
S
K
Q
E
V
E
R
F
L
-
R
P
F
A
G
-
T
-
P
L
F
V
K
V
G
M
E
L
Y
Y
Q
E
G
P
----
A
I
V
A
F
L
K
E
Q
G
-
H
A
V
F
L
D
L
K
L
H
D
I
P
N
T
V
K
Q
A
M
K
G
-
L
A
R
V
G
A
D
L
V
N
V
H
A
A
G
G
R
R
M
M
E
A
A
I
E
G
L
D
A
----
G
---
T
P
S
G
R
M
R
P
R
C
I
A
V
T
Q
L
T
S
T
D
E
R
M
L
H
E
E
L
W
I
S
R
P
L
V
E
T
V
A
H
Y
A
----
A
L
A
K
E
S
G
L
D
G
V
V
C
S
A
N
E
A
A
F
I
K
E
R
C
G
A
S
F
L
A
V
T
-----------------
V
T
P
R
K
A
R
A
L
G
S
D
Y
I
V
I
G
R
S
L
T
R
A
-
A
D
P
L
R
T
Y
A
R
L
Q
H
E
W
N
--
22
PsiBlast_CBE
87.32
56%
-115
- C3 -
-
1DBT
1
PYRF_BACSU
C:
[3-234]
----
N
N
L
P
I
I
A
L
D
F
A
S
A
E
E
T
L
A
F
L
-
A
P
F
-
Q
-
Q
E
P
L
F
V
K
V
G
M
E
L
F
Y
Q
E
G
P
----
S
I
V
K
Q
L
K
E
R
N
-
C
E
L
F
L
D
L
K
L
H
D
I
P
T
T
V
N
K
A
M
K
R
-
L
A
S
L
G
V
D
L
V
N
V
H
A
A
G
G
K
K
M
M
Q
A
A
L
E
G
L
E
E
----
G
---
T
P
A
G
K
K
R
P
S
L
I
A
V
T
Q
L
T
S
T
S
E
Q
I
M
K
D
E
L
L
I
E
K
S
L
I
D
T
V
V
H
Y
S
----
K
Q
A
E
E
S
G
L
D
G
V
V
C
S
V
H
E
A
K
A
I
Y
Q
A
V
S
P
S
F
L
T
V
T
P
G
I
R
M
S
-
E
D
A
A
N
D
Q
V
R
V
A
T
P
A
I
A
R
E
K
G
S
S
A
I
V
V
G
R
S
I
T
K
A
-
E
D
P
V
K
A
Y
K
A
V
R
L
E
W
---
31
HHSearch
87.22
56%
-65
- C3 -
-
1DBT
2
PYRF_BACSU
A:
[1-235]
--
M
K
N
N
L
P
I
I
A
L
D
F
A
S
A
E
E
T
L
A
F
L
-
A
P
F
-
Q
-
Q
E
P
L
F
V
K
V
G
M
E
L
F
Y
Q
E
G
P
----
S
I
V
K
Q
L
K
E
R
N
-
C
E
L
F
L
D
L
K
L
H
D
I
P
T
T
V
N
K
A
M
K
R
-
L
A
S
L
G
V
D
L
V
N
V
H
A
A
G
G
K
K
M
M
Q
A
A
L
E
G
L
E
E
----
G
TPA
G
K
---
K
R
P
S
L
I
A
V
T
Q
L
T
S
T
S
E
Q
I
M
K
D
E
L
L
I
E
K
S
L
I
D
T
V
V
H
Y
S
----
K
Q
A
E
E
S
G
L
D
G
V
V
C
S
V
H
E
A
K
A
I
Y
Q
A
V
S
P
S
F
L
T
V
T
P
G
I
R
M
S
-
E
D
A
A
N
D
Q
V
R
V
A
T
P
A
I
A
R
E
K
G
S
S
A
I
V
V
G
R
S
I
T
K
A
-
E
D
P
V
K
A
Y
K
A
V
R
L
E
W
E
--
23
PsiBlast_CBE
86.43
56%
-120
- C3 -
-
1DBT
2
PYRF_BACSU
B:
[3-234]
----
N
N
L
P
I
I
A
L
D
F
A
S
A
E
E
T
L
A
F
L
-
A
P
F
-
Q
-
Q
E
P
L
F
V
K
V
G
M
E
L
F
Y
Q
E
G
P
----
S
I
V
K
Q
L
K
E
R
N
-
C
E
L
F
L
D
L
K
L
H
D
I
P
T
T
V
N
K
A
M
K
R
-
L
A
S
L
G
V
D
L
V
N
V
H
A
A
G
G
K
K
M
M
Q
A
A
L
E
G
L
E
E
----
G
---
T
P
A
G
K
K
R
P
S
L
I
A
V
T
Q
L
T
S
T
S
E
Q
I
M
K
D
E
L
L
I
E
K
S
L
I
D
T
V
V
H
Y
S
----
K
Q
A
E
E
S
G
L
D
G
V
V
C
S
V
H
E
A
K
A
I
Y
Q
A
V
S
P
S
F
L
T
V
T
P
G
I
R
M
S
-
E
D
A
A
N
D
Q
V
R
V
A
T
P
A
I
A
R
E
K
G
S
S
A
I
V
V
G
R
S
I
T
K
A
-
E
D
P
V
K
A
Y
K
A
V
R
L
E
W
---
32
HHSearch
84.69
56%
-67
- C3 -
-
1DBT
2
PYRF_BACSU
B:
[3-235]
----
N
N
L
P
I
I
A
L
D
F
A
S
A
E
E
T
L
A
F
L
-
A
P
F
-
Q
-
Q
E
P
L
F
V
K
V
G
M
E
L
F
Y
Q
E
G
P
----
S
I
V
K
Q
L
K
E
R
N
-
C
E
L
F
L
D
L
K
L
H
D
I
P
T
T
V
N
K
A
M
K
R
-
L
A
S
L
G
V
D
L
V
N
V
H
A
A
G
G
K
K
M
M
Q
A
A
L
E
G
L
E
E
----
G
TPA
G
K
---
K
R
P
S
L
I
A
V
T
Q
L
T
S
T
S
E
Q
I
M
K
D
E
L
L
I
E
K
S
L
I
D
T
V
V
H
Y
S
----
K
Q
A
E
E
S
G
L
D
G
V
V
C
S
V
H
E
A
K
A
I
Y
Q
A
V
S
P
S
F
L
T
V
T
P
G
I
R
M
S
-
E
D
A
A
N
D
Q
V
R
V
A
T
P
A
I
A
R
E
K
G
S
S
A
I
V
V
G
R
S
I
T
K
A
-
E
D
P
V
K
A
Y
K
A
V
R
L
E
W
E
--
52
Fugue
81.52
55%
-5
- C3 -
-
1DBT
2
PYRF_BACSU
A:
[1-237]
--
M
K
N
N
L
P
I
I
A
L
D
F
A
S
A
E
E
T
L
A
F
L
-
A
P
F
Q
Q
-
E
-
P
L
F
V
K
V
G
M
E
L
F
Y
Q
E
G
P
S
I
V
K
Q
L
K
E
R
----
N
-
C
E
L
F
L
D
L
K
L
H
D
I
P
T
T
V
N
K
A
M
K
-
R
L
A
S
L
G
V
D
L
V
N
V
H
A
A
G
G
K
K
M
M
Q
A
A
L
E
G
L
E
E
----
G
---
T
P
A
G
K
K
R
P
S
L
I
A
V
T
Q
L
T
S
T
S
E
Q
I
M
K
D
E
L
L
I
E
K
S
L
I
D
T
V
V
H
Y
S
----
K
Q
A
E
E
S
G
L
D
G
V
V
C
S
V
H
E
A
K
A
I
Y
Q
A
V
S
P
S
F
L
T
V
T
P
G
I
R
M
-S
E
D
A
A
N
D
Q
V
R
V
A
T
P
A
I
A
R
E
K
G
S
S
A
I
V
V
G
R
S
I
T
K
A
E-
D
P
V
K
A
Y
K
A
V
R
L
E
W
E
GI
36
HHSearch
80.54
42%
-134
- C3 -
-
3LDV
-
PYRF_VIBCH
A:
[24-254]
-
A
M
N
D
P
K
V
I
V
A
L
D
Y
D
N
L
A
D
A
L
A
F
V
-
D
K
I
-
D
-
P
S
T
C
R
L
K
V
G
K
E
M
F
T
L
F
G
P
----
D
F
V
R
E
L
H
K
R
G
-
F
S
V
F
L
D
L
K
F
H
D
I
P
N
T
C
S
K
A
V
K
A
-
A
A
E
L
G
V
W
M
V
N
V
H
A
S
G
G
E
R
M
M
A
A
S
R
E
I
L
E
P
----
Y
---
G
K
---
E
R
P
L
L
I
G
V
T
V
L
T
S
M
E
S
A
D
L
Q
G
-
I
G
I
L
S
A
P
Q
D
H
V
L
R
L
A
----
T
L
T
K
N
A
G
L
D
G
V
V
C
S
A
Q
E
A
S
L
L
K
Q
H
L
G
R
E
F
K
L
V
T
P
G
I
R
P
A
-
G
S
E
Q
G
D
Q
R
R
I
M
T
P
A
Q
A
I
A
S
G
S
D
Y
L
V
I
G
R
P
I
T
Q
A
-
A
H
P
E
V
V
L
E
E
I
N
S
S
L
---
24
PsiBlast_CBE
76.82
43%
-28
- C3 -
-
3UWQ
7
PYRF_VIBCH
B:
[27-252]
----
D
P
K
V
I
V
A
L
D
Y
D
N
L
A
D
A
L
A
F
V
D
K
I
D
P
S
-
T
C
R
L
--
K
V
G
K
E
M
F
T
L
F
G
P
----
D
F
V
R
E
L
H
K
R
G
-
F
S
V
F
L
D
L
K
F
H
D
I
P
N
T
C
S
K
A
V
K
A
-
A
A
E
L
G
V
W
M
V
N
V
H
A
S
G
G
E
R
M
M
A
A
S
R
E
I
L
E
----------
P
Y
G
K
E
R
P
L
L
I
G
V
T
V
L
T
S
M
E
S
A
D
L
Q
G
I
G
I
L
S
A
P
-
Q
D
H
V
L
R
L
A
----
T
L
T
K
N
A
G
L
D
G
V
V
C
S
A
Q
E
A
S
L
L
K
Q
H
L
G
R
E
F
K
L
V
T
P
G
I
R
P
A
-
G
S
----
Q
R
R
I
M
T
P
A
Q
A
I
A
S
G
S
D
Y
L
V
I
G
R
P
I
T
Q
A
-
A
H
P
E
V
V
L
E
E
I
N
S
-----
4
PsiBlast_PDB
76.47
43%
-125
- C3 -
-
3TFX
-
PYRF_LACAC
A:
[2-235]
----
D
R
P
V
I
V
A
L
D
L
D
N
E
E
Q
L
N
K
I
L
-
S
K
L
G
D
-
P
H
D
V
F
V
K
V
G
M
E
L
F
Y
N
A
G
I
----
D
V
I
K
K
L
T
Q
Q
G
-
Y
K
I
F
L
D
L
K
M
H
D
I
P
N
T
V
Y
N
G
A
K
A
-
L
A
K
L
G
I
T
F
T
T
V
H
A
L
G
G
S
Q
M
I
K
S
A
K
D
G
L
I
A
----
G
---
T
P
A
G
H
S
V
P
K
L
L
A
V
T
E
L
T
S
I
S
D
D
V
L
R
N
E
Q
N
C
R
L
P
M
A
E
Q
V
L
S
L
A
----
K
M
A
K
H
S
G
A
D
G
V
I
C
S
P
L
E
V
K
K
L
H
E
N
I
G
D
D
F
L
Y
V
T
P
G
I
R
P
A
------------
T
P
K
M
A
K
E
W
G
S
S
A
I
V
V
G
R
P
I
T
L
A
-
S
D
P
K
A
A
Y
E
A
I
K
K
E
F
N
--
5
PsiBlast_PDB
76.28
43%
-23
- C3 -
-
3LDV
-
PYRF_VIBCH
A:
[27-252]
----
D
P
K
V
I
V
A
L
D
Y
D
N
L
A
D
A
L
A
F
V
D
K
I
D
P
S
-
T
C
R
L
--
K
V
G
K
E
M
F
T
L
F
G
P
----
D
F
V
R
E
L
H
K
R
G
-
F
S
V
F
L
D
L
K
F
H
D
I
P
N
T
C
S
K
A
V
K
A
-
A
A
E
L
G
V
W
M
V
N
V
H
A
S
G
G
E
R
M
M
A
A
S
R
E
I
L
E
----------
P
Y
G
K
E
R
P
L
L
I
G
V
T
V
L
T
S
M
E
S
A
D
L
Q
G
I
G
I
L
S
A
P
-
Q
D
H
V
L
R
L
A
----
T
L
T
K
N
A
G
L
D
G
V
V
C
S
A
Q
E
A
S
L
L
K
Q
H
L
G
R
E
F
K
L
V
T
P
G
I
R
P
A
-
G
S
E
Q
G
D
Q
R
R
I
M
T
P
A
Q
A
I
A
S
G
S
D
Y
L
V
I
G
R
P
I
T
Q
A
-
A
H
P
E
V
V
L
E
E
I
N
S
-----
6
PsiBlast_PDB
76.09
43%
-27
- C3 -
-
3UWQ
7
PYRF_VIBCH
A:
[27-252]
----
D
P
K
V
I
V
A
L
D
Y
D
N
L
A
D
A
L
A
F
V
D
K
I
D
P
S
-
T
C
R
L
--
K
V
G
K
E
M
F
T
L
F
G
P
----
D
F
V
R
E
L
H
K
R
G
-
F
S
V
F
L
D
L
K
F
H
D
I
P
N
T
C
S
K
A
V
K
A
-
A
A
E
L
G
V
W
M
V
N
V
H
A
S
G
G
E
R
M
M
A
A
S
R
E
I
L
E
----------
P
Y
G
K
E
R
P
L
L
I
G
V
T
V
L
T
S
M
E
S
A
D
L
Q
G
I
G
I
L
S
A
P
-
Q
D
H
V
L
R
L
A
----
T
L
T
K
N
A
G
L
D
G
V
V
C
S
A
Q
E
A
S
L
L
K
Q
H
L
G
R
E
F
K
L
V
T
P
G
I
R
P
A
--------
R
R
I
M
T
P
A
Q
A
I
A
S
G
S
D
Y
L
V
I
G
R
P
I
T
Q
A
-
A
H
P
E
V
V
L
E
E
I
N
S
-----
39
HHSearch
74.80
40%
-124
* C3 *
-
1EIX
2
PYRF_ECOLI
C:
[12-241]
--
V
T
N
S
P
V
V
V
A
L
D
Y
H
N
R
D
D
A
L
A
F
V
-
D
K
I
-
D
-
P
R
D
C
R
L
K
V
G
K
E
M
F
T
L
F
G
P
----
Q
F
V
R
E
L
Q
Q
R
G
-
F
D
I
F
L
D
L
K
F
H
D
I
P
N
T
A
A
H
A
V
A
A
-
A
A
D
L
G
V
W
M
V
N
V
H
A
S
G
G
A
R
M
M
T
A
A
R
E
A
L
V
P
----
F
---
G
K
---
D
A
P
L
L
I
A
V
T
V
L
T
S
M
E
A
S
D
L
V
D
-
L
G
M
T
L
S
P
A
D
Y
A
E
R
L
A
----
A
L
T
Q
K
C
G
L
D
G
V
V
C
S
A
Q
E
A
V
R
F
K
Q
V
F
G
Q
E
F
K
L
V
T
P
G
I
R
P
Q
-
G
S
E
A
G
D
Q
R
R
I
M
T
P
E
Q
A
L
S
A
G
V
D
Y
M
V
I
G
R
P
V
T
Q
S
-
V
D
P
A
Q
T
L
K
A
I
N
A
S
L
---
34
HHSearch
70.72
43%
9
- C3 -
-
3TFX
-
PYRF_LACAC
A:
[2-235]
----
D
R
P
V
I
V
A
L
D
L
D
N
E
E
Q
L
N
K
I
L
-
S
K
L
-
G
D
P
H
D
V
F
V
K
V
G
M
E
L
F
Y
N
A
G
I
----
D
V
I
K
K
L
T
Q
Q
G
-
Y
K
I
F
L
D
L
K
M
H
D
I
P
N
T
V
Y
N
G
A
K
A
-
L
A
K
L
G
I
T
F
T
T
V
H
A
L
G
G
S
Q
M
I
K
S
A
K
D
G
L
I
A
G
TPA
G
---
H
----
S
V
P
K
L
L
A
V
T
E
L
T
S
I
S
D
D
V
L
R
N
E
Q
N
C
R
L
P
M
A
E
Q
V
L
S
L
A
----
K
M
A
K
H
S
G
A
D
G
V
I
C
S
P
L
E
V
K
K
L
H
E
N
I
G
D
D
F
L
Y
V
T
P
G
I
R
P
A
------------
T
P
K
M
A
K
E
W
G
S
S
A
I
V
V
G
R
P
I
T
L
A
-
S
D
P
K
A
A
Y
E
A
I
K
K
E
F
N
--
26
PsiBlast_CBE
70.63
43%
-9
- C3 -
-
1EIX
2
PYRF_ECOLI
D:
[18-238]
--------
V
V
A
L
D
Y
H
N
R
D
D
A
L
A
F
V
D
K
I
D
P
R
-
D
C
R
L
--
K
V
G
K
E
M
F
T
L
F
G
P
----
Q
F
V
R
E
L
Q
Q
R
G
-
F
D
I
F
L
D
L
K
F
H
D
I
P
N
T
A
A
H
A
V
A
A
-
A
A
D
L
G
V
W
M
V
N
V
H
A
S
G
G
A
R
M
M
T
A
A
R
E
A
L
----------
V
P
F
G
K
D
A
P
L
L
I
A
V
T
V
L
T
S
-----
M
E
A
S
D
L
V
D
L
G
M
T
L
S
P
A
D
Y
A
ERLA
A
L
T
Q
K
C
G
L
D
G
V
V
C
S
A
Q
E
A
V
R
F
K
Q
V
F
G
Q
E
F
K
L
V
T
P
G
I
R
P
Q
-
G
S
E
A
G
D
Q
R
R
I
M
T
P
E
Q
A
L
S
A
G
V
D
Y
M
V
I
G
R
P
V
T
Q
S
-
V
D
P
A
Q
T
L
K
A
I
N
------
10
PsiBlast_PDB
70.45
37%
-55
- C3 -
-
3RU6
-
PYRF_CAMJE
A:
[29-239]
---------
V
A
L
D
L
S
T
K
E
E
C
L
Q
L
A
-
K
E
L
-
K
-
N
L
D
I
W
L
K
V
G
L
R
A
Y
L
R
D
G
F
----
K
F
I
E
E
L
K
K
V
D
D
F
K
I
F
L
D
L
K
F
H
D
I
P
N
T
M
A
D
A
C
E
E
-
V
S
K
L
G
V
D
M
I
N
I
H
A
S
A
G
K
I
A
I
Q
E
V
M
T
R
L
S
K
----
F
---
S
----
K
R
P
L
V
L
A
V
S
A
L
T
S
F
D
E
E
N
F
F
S
--
I
Y
R
Q
K
I
E
E
A
V
I
N
F
S
----
K
I
S
Y
E
N
G
L
D
G
M
V
C
S
V
F
E
S
K
K
I
K
E
H
T
S
S
N
F
L
T
L
T
P
G
I
R
P
F
-
G
--------
V
A
N
L
A
M
A
R
E
N
L
S
D
Y
I
V
V
G
R
P
I
Y
K
N
-
E
N
P
--------------
27
PsiBlast_CBE
69.24
43%
-11
- C3 -
-
1EIX
2
PYRF_ECOLI
C:
[18-238]
--------
V
V
A
L
D
Y
H
N
R
D
D
A
L
A
F
V
D
K
I
D
P
R
-
D
C
R
L
--
K
V
G
K
E
M
F
T
L
F
G
P
----
Q
F
V
R
E
L
Q
Q
R
G
-
F
D
I
F
L
D
L
K
F
H
D
I
P
N
T
A
A
H
A
V
A
A
-
A
A
D
L
G
V
W
M
V
N
V
H
A
S
G
G
A
R
M
M
T
A
A
R
E
A
L
----------
V
P
F
G
K
D
A
P
L
L
I
A
V
T
V
L
T
S
-----
M
E
A
S
D
L
V
D
L
G
M
T
L
S
P
A
D
Y
A
ERLA
A
L
T
Q
K
C
G
L
D
G
V
V
C
S
A
Q
E
A
V
R
F
K
Q
V
F
G
Q
E
F
K
L
V
T
P
G
I
R
P
Q
-
G
S
E
A
G
D
Q
R
R
I
M
T
P
E
Q
A
L
S
A
G
V
D
Y
M
V
I
G
R
P
V
T
Q
S
-
V
D
P
A
Q
T
L
K
A
I
N
------
28
PsiBlast_CBE
69.04
43%
-17
- C3 -
-
1EIX
2
PYRF_ECOLI
B:
[18-238]
--------
V
V
A
L
D
Y
H
N
R
D
D
A
L
A
F
V
D
K
I
D
P
R
-
D
C
R
L
--
K
V
G
K
E
M
F
T
L
F
G
P
----
Q
F
V
R
E
L
Q
Q
R
G
-
F
D
I
F
L
D
L
K
F
H
D
I
P
N
T
A
A
H
A
V
A
A
-
A
A
D
L
G
V
W
M
V
N
V
H
A
S
G
G
A
R
M
M
T
A
A
R
E
A
L
----------
V
P
F
G
K
D
A
P
L
L
I
A
V
T
V
L
T
S
-----
M
E
A
S
D
L
V
D
L
G
M
T
L
S
P
A
D
Y
A
ERLA
A
L
T
Q
K
C
G
L
D
G
V
V
C
S
A
Q
E
A
V
R
F
K
Q
V
F
G
Q
E
F
K
L
V
T
P
G
I
R
P
Q
-
G
S
E
A
G
D
Q
R
R
I
M
T
P
E
Q
A
L
S
A
G
V
D
Y
M
V
I
G
R
P
V
T
Q
S
-
V
D
P
A
Q
T
L
K
A
I
N
------
7
PsiBlast_PDB
68.56
43%
-11
- C3 -
-
1EIX
2
PYRF_ECOLI
A:
[18-238]
--------
V
V
A
L
D
Y
H
N
R
D
D
A
L
A
F
V
D
K
I
D
P
R
-
D
C
R
L
--
K
V
G
K
E
M
F
T
L
F
G
P
----
Q
F
V
R
E
L
Q
Q
R
G
-
F
D
I
F
L
D
L
K
F
H
D
I
P
N
T
A
A
H
A
V
A
A
-
A
A
D
L
G
V
W
M
V
N
V
H
A
S
G
G
A
R
M
M
T
A
A
R
E
A
L
----------
V
P
F
G
K
D
A
P
L
L
I
A
V
T
V
L
T
S
-----
M
E
A
S
D
L
V
D
L
G
M
T
L
S
P
A
D
Y
A
E
R
L
A
A
L
T
Q
K
C
G
L
D
G
V
V
C
S
A
Q
E
A
V
R
F
K
Q
V
F
G
Q
E
F
K
L
V
T
P
G
I
R
P
Q
-
G
S
E
A
G
D
Q
R
R
I
M
T
P
E
Q
A
L
S
A
G
V
D
Y
M
V
I
G
R
P
V
T
Q
S
-
V
D
P
A
Q
T
L
K
A
I
N
------