@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3XZI5: (2018-01-14 )
MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALTLGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFFAVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILELKLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKIGIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLADAMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAGIINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKKGQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAELQK
Atome Classification :
(19 SA)
.........10...---.....20........30-........40........50........60........70........80........90-----..-----......100.......110....-.-.--.120.......130.---......140-..--.....150....-...160.......170.......180.---......190.......---200----.-......-..210.....--..220-........230.......-------.240-------.......250.-......260---.........270.....---------..280.......290.-......-300.-......310..------.....320.-...-..---.330----....-...340.--...---.-------..350.......360.-......370.......380.......-390.......400.......410.......420.......430.......440.......450.----
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
E
V
F
Q
T
I
I
N
Y
V
L
N
L---
G
S
A
I
F
V
P
L
I
I
L
I
L
G
L
LA-
G
M
K
L
K
K
A
F
M
S
A
L
T
L
G
I
A
F
S
G
M
S
M
V
I
G
Y
M
SNAVS
P
A
S
E
A
L
AKNTGISLPALDLGWTG
A
A
S
I
-----
T
W
-----SW
S
Y
A
F
I
F
F
A
V
T
I
G
V
N
F
V
L
L
L
FN-W-T--K
T
L
N
V
D
M
W
N
V
W
G
K
A
L
---
T
A
Y
L
V
Y
YVS-G
S
--
L
A
A
G
F
L
T
A
M
V
Q
V
-
I
L
E
LK
L
G
D
M
F
Q
K
H
I
Q
D
LTGIP
L
V
T
V
T
H
---
F
M
T
S
A
A
V
L
L
L
P
F
N
M
I
M
---
D
------K-IPALNK-RA
D
T
N
A
L
K
K
K
--IGIF--SENS
V
M
G
F
I
I
-
G
L
G
L
G
F
A
-------
A
A
YG-------VSG
S
L
N
L
A
I
Q
T
-
A
T
A
L
S
L
F
-----
P
M
I
S
K
M
F
M
Q
S
L
S
P
L
A
D
A
---------
M
S
E
F
M
K
K
RFKDR
E
V
Y
I
-GLDWPI-LAGR-S
E
I
W
V
T
A
I
L
L
V
------
P
V
F
I
G
Y
A
I
I
-LPG-N
Q
---
V
L
P
L
----
A
G
I
I
-
N
Y
S
I
A
V
G
--
G
L
L
---L-------TG
G
N
L
A
R
M
L
I
L
G
I
I
T
M
-
P
I
Y
L
Y
G
A
T
Y
L
A
P
I
L
S
D
L
A
E
KSGAVEG-IKKG
Q
L
I
T
W
SSIEGP
E
F
R
V
L
F
A
E
A
FNR
N
I
L
A
I
V
G
C
V
I
F
L
G
L
F
V
L
L
Y
K
Y
M
I
KAKV
P
S
E
R
Y
A
E
LQK----
16
Fugue
65.64
16%
-143
- C2 -
-
4RP9
8
ULAA_ECOLI
A:
[6-456]
-
N
I
F
T
V
F
F
N
Q
V
M
T
-----
N
A
P
L
L
L
G
I
V
T
C
L
G
Y
I
L
L
R
K
S
V
S
V
I
I
K
G
T
I
K
T
I
I
G
F
M
L
L
Q
A
G
S
G
I
L
T
S
T
F
K
P
V
V
A
K
M
S
E
V
Y
G
I
N
G
A
I
S
D
T
Y
A
S
M
M
A
T
I
-----
D
R
M
GDAY
S
W
V
G
Y
A
V
L
L
A
L
A
L
N
I
C
Y
V
L
L
R
R
I
T
G
-
I
--
R
T
I
M
L
T
G
H
I
M
F
Q
Q
A
G
---
L
I
A
V
T
L
F
I
F
-
G
Y
S
M
W
T
T
I
I
C
T
A
I
L
V
S
-
L
Y
W
G
I
T
S
N
M
M
Y
K
P
T
Q
E
V
T
D
G
C
G
F
S
I
G
H
QQ
Q
F
A
S
W
I
A
Y
K
V
A
P
F
L
G
K
K
---
E
ESVE
D
L
K
-
L
P
G
W
L
N
-
I
F
H
D
N
I
V
S
T
A
--
I
V
M
T
--
I
F
F
G
A
I
L
L
S
F
-
G
I
D
T
V
Q
A
-------
M
A
G
K
-------
V
H
W
T
V
Y
I
L
Q
T
G
-
F
S
F
A
V
A
I
-----
F
I
I
T
Q
G
V
R
M
F
V
A
E
L
S
E
A
---------
F
N
G
I
S
Q
R
L
I
P
G
A
V
L
A
I
D
C
A
A
I
Y
S
-
F
A
P
N
-
A
V
V
W
G
F
M
W
G
T
I
------
G
Q
L
I
A
V
G
I
L
-
V
A
C
-
G
S
S
I
L
I
I
P
G
----
F
I
P
M
-
F
F
S
N
A
T
I
--
G
V
F
---
A
-------
N
H
F
G
G
W
R
A
A
L
K
I
C
L
V
M
-
G
M
I
E
I
F
G
C
V
W
A
V
K
L
T
G
M
----
S
A
W
M
G
------
M
A
D
W
S
I
L
A
P
P
M
M
Q
G
F
F
S
I
G
--------
I
A
F
M
A
V
I
I
V
I
A
L
A
Y
M
F
F
A
G
R
A
L
R
A
E
E
D
A
--------
20
Fugue
59.83
13%
-69
- C1 -
-
1TUB
1
TBA1A_PIG
A:
[1-440]
---
M
R
E
C
I
S
I
H
V
G
Q
---
A
G
V
Q
I
G
N
A
C
W
E
L
Y
C
L
E
H
-
G
I
Q
P
D
G
Q
---
M
P
S
D
K
T
I
G
G
G
D
D
S
F
N
T
F
F
S
E
T
G
A
G
K
H
V
P
R
A
V
F
V
D
L
E
P
T
V
I
D
E
V
R
T
G
T
Y
R
Q
-----
L
F
-----
H
P
E
Q
L
I
T
G
K
-
E
D
A
A
N
N
Y
A
R
G
H
Y
T
-
I
-
G
--
K
E
I
I
D
L
V
L
D
R
I
R
K
L
A
D
QC
T
G
L
Q
G
F
S
V
F
-
H
S
--
F
G
G
G
T
G
S
G
F
T
S
L
-
L
M
E
R
L
S
V
D
Y
G
K
K
S
K
L
E
F
S
I
Y
P
A
P
Q
V
S
T
---
A
V
V
E
P
Y
N
S
I
L
T
T
H
T
T
L
EHS
D
------
C
-
A
F
M
V
D
N
-
E
A
I
Y
D
I
C
R
R
N
--
L
D
I
E
RP
T
Y
T
N
L
N
R
L
I
G
-
Q
I
V
S
S
I
T
-------
A
S
L
R
-------
F
D
G
A
L
N
V
D
L
T
E
F
Q
T
N
L
V
P
Y
-----
P
R
G
-
H
F
P
L
A
T
Y
A
P
V
I
S
A
EKAYHEQLS
V
A
E
I
T
N
A
C
F
E
P
A
N
Q
M
V
-
K
C
D
------
P
R
-
H
G
K
Y
M
A
C
C
L
L
Y
R
G
DVV
P
K
D
V
N
A
A
I
A
T
-
I
K
T
-
K
R
---
T
I
Q
F
----
V
D
W
C
-
P
T
G
F
K
V
G
--
I
N
Y
---
E
-------
P
P
T
V
V
P
G
G
D
L
A
K
V
Q
R
A
-
V
C
M
L
S
N
T
T
A
I
A
E
A
W
A
R
L
D
H
K
F
D
L
M
---
Y
A
K
R
A
F
V
H
W
Y
V
G
E
G
M
E
----------------------
E
G
E
F
S
E
A
R
E
D
M
A
A
L
E
K
D
Y
E
E
V
G
V
D
S
V
----
5
HHSearch
59.35
16%
-132
- C2 -
-
4RP9
8
ULAA_ECOLI
A:
[6-403]
-----
N
I
F
T
V
F
F
N
Q
VMT
N
A
P
L
L
L
G
I
V
T
C
L
G
Y
I
L
L
-
R
K
S
V
S
V
I
I
K
G
T
I
K
T
I
I
G
F
M
L
L
Q
A
G
S
G
I
L
T
S
T
F
K
P
V
V
A
K
M
S
E
V
Y
G
I
N
G
A
I
S
D
T
Y
A
S
M
M
A
T
I
D
R
M
GD
A
Y
-----
S
W
--
V
G
Y
A
V
L
L
A
L
A
L
N
I
C
Y
V
L
L
R
-
R
I
T
GI
R
T
I
M
L
T
G
H
I
M
F
Q
Q
A
G
---
L
I
A
V
T
L
F
I
F
G
Y
S
--
M
W
T
T
I
I
C
T
A
I
L
V
S
L
Y
W
G
I
T
S
N
M
M
Y
K
P
T
Q
E
V
T
D
G
C
G
F
S
I
G
H
---
Q
Q
Q
F
-------
A
S
W
I
A
---
Y
------
K
V
A
P
F
L
G
K
K
E
E
S
V
E
D
L
K
L
P
G
W
L
N
I
F
--
H
D
N
I
V
S
T
A
I
V
M
T
I
F
F
G
A
I
L
L
S
F
G
I
D
T
V
Q
A
M
A
GKVH
W
T
V
Y
I
L
Q
T
G
F
S
F
-
A
V
A
I
F
I
I
-----
T
Q
G
V
R
M
F
V
A
E
---
L
S
E
A
---------
F
N
G
I
S
Q
R
L
I
P
G
A
--
V
L
-
A
I
D
C
A
A
-
I
Y
S
F
A
P
N
A
V
V
W
G
F
M
W
G
------
T
I
G
Q
L
I
A
V
G
I
L
V
A
-
C
G
---
S
-
S
I
----
L
I
I
P
G
F
I
P
M
F
F
S
N
A
T
I
G
---
V
F
A
N
H
F
GG
W
R
A
A
L
K
I
C
L
V
M
G
M
I
E
I
-
F
G
C
V
W
A
V
K
L
T
G
------------------------------------------------------------------------------------
15
Fugue
53.83
11%
-689
- C2 -
-
2YJN
-
ERYC3_SACEN
A:
[19-436]
---
S
H
M
R
V
V
F
S
S
M
A
---
S
K
S
H
L
F
G
L
V
P
L
A
W
A
F
R
A
A
G
H
E
V
R
V
V
A
S
P
A
L
T
E
D
I
T
A
A
G
L
T
A
V
P
V
G
T
D
V
D
L
V
D
F
M
T
H
A
G
H
D
I
I
D
Y
V
R
S
L
D
F
S
E
R
D
P
A
T
L
-----
T
W
-----
E
H
L
L
G
M
Q
T
V
L
T
P
T
F
------
Y
A
L
-
M
-
S
--
P
D
T
L
I
E
G
M
V
S
F
C
R
K
W
---
R
P
D
L
V
I
W
E
P
-
L
T
--
F
A
A
P
I
A
A
A
V
T
---------------------
G
T
P
H
A
R
L
L
W
---
G
P
D
I
T
T
R
A
R
Q
N
F
L
G
L
L
---
P
------
D
-
Q
P
--
E
E
-
H
R
E
D
P
L
A
E
W
L
--
T
W
T
L
--
E
K
Y
G
G
P
A
F
D
E
-
E
V
V
V
G
Q
W
-------
T
I
D
P
-------
A
P
A
A
I
R
L
D
T
G
L
-
K
T
V
G
M
R
Y
V
D
Y
N
G
P
S
V
V
P
E
W
L
H
D
E
P
E
R
R
R
V
---------
C
L
T
L
Q
V
S
I
E
E
L
L
G
A
V
G
-
D
V
D
A
E
I
-
I
A
T
F
-
D
A
Q
Q
L
E
G
V
A
N
I
------
P
D
N
V
R
T
V
G
F
-
V
P
M
-
H
A
---
L
L
P
T
----
C
A
-------------
A
T
---
V
-------
H
H
G
G
P
G
S
W
H
T
A
A
I
H
G
V
-
P
Q
V
I
L
P
D
G
W
D
T
G
V
R
A
Q
R
T
Q
E
F
G
A
-------
G
I
A
L
P
V
P
E
L
T
--------
P
D
Q
L
R
E
S
V
K
R
V
L
D
D
P
A
H
R
A
G
A
A
R
M
R
D
D
M
L
A
E
P
S
P
A
E
V
V
G
I
C
E
E
L
A
A
G
4
PsiBlast_CBE
32.39
31%
-366
- C2 -
-
4PL0
1
MCJD_ECOLX
B:
[263-306]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
F
G
S
V
F
I
Y
N
I
L
G
V
L
N
G
V
V
S
I
G
H
F
I
M
I
T
S
Y
I
I
L
L
S
T
P
V
E
N
I
G
A
L
------
11
HHSearch
32.26
45%
-59
- C2 -
-
2NSC
-
TIG_THEMA
A:
[40-60]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
-
I
P
G
F
R
K
G
R
I
P
K
N
V
L
K
M
K
--
L
G
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
31.29
31%
-346
- C2 -
-
5EG1
-
MCJD_ECOLX
A:
[263-306]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
F
G
S
V
F
I
Y
N
I
L
G
V
L
N
G
V
V
S
I
G
H
F
I
M
I
T
S
Y
I
I
L
L
S
T
P
V
E
N
I
G
A
L
------
1
PsiBlast_PDB
30.90
31%
-352
- C2 -
-
4PL0
1
MCJD_ECOLX
A:
[263-306]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
F
G
S
V
F
I
Y
N
I
L
G
V
L
N
G
V
V
S
I
G
H
F
I
M
I
T
S
Y
I
I
L
L
S
T
P
V
E
N
I
G
A
L
------
6
HHSearch
29.20
12%
-167
- C2 -
-
4RP9
5
ULAA_ECOLI
A:
[15-195]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
M
--
T
N
A
P
L
L
L
G
I
V
-
T
C
L
G
Y
I
L
-------
L
R
K
S
-------
V
S
V
I
I
K
G
T
I
K
T
-
I
I
G
F
M
L
L
-----
Q
A
G
S
G
I
L
T
S
T
F
K
P
V
V
A
K
---------
M
S
E
V
Y
G
I
N
G
A
I
S
D
T
Y
A
-
S
M
M
A
T
I
D
R
M
---
G
D
A
Y
S
W
V
G
Y
A
V
------
L
L
A
L
A
L
N
I
C
-
Y
V
L
L
R
R
---
I
T
G
I
RTIM
L
T
G
H
-
I
M
F
Q
Q
A
G
L
-
I
A
V
T
L
F
I
-------
F
G
Y
S
M
W
T
T
I
I
C
T
A
I
L
V
S
L
Y
W
G
I
T
S
N
M
M
Y
K
P
T
Q
E
V
T
D
G
C
G
---
F
S
I
G
H
Q
----------------------------------------------------------------
9
HHSearch
21.83
26%
11
- C2 -
-
1P9Y
-
TIG_ECOLI
B:
[43-62]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
-
I
D
G
L
R
K
G
K
V
P
M
N
I
V
A
Q
R
--
Y
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
19.71
22%
35
- C2 -
-
2A7U
-
ATPA_SHIF8
A:
[1-22]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Q
L
N
S
T
E
---------
I
S
E
L
I
K
Q
R
I
A
Q
F
N
V
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
18.34
19%
-
- C- -
-
4ZMK
-
TAZ1_SCHPO
A:
[408-478]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
T
F
--
S
E
R
T
--------
L
G
L
N
S
I
-------
D
N
T
E
-------
I
S
E
V
V
S
L
G
L
V
S
-
S
A
L
D
K
I
T
-----
G
L
L
S
A
D
N
L
S
E
T
V
S
Q
A
R
D
---------
F
S
H
T
L
S
K
S
L
K
S
R
A
K
S
L
-
S
Q
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
Fugue
14.13
26%
-76
- C2 -
-
2PCO
-
A:
[1-26]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
M
W
S
G
M
W
R
R
K
L
K
K
L
R
N
A
---------
L
K
K
K
L
K
G
E
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
Fugue
13.79
24%
-44
- C2 -
-
5B16
-
DGCR8_HUMAN
B:
[1-25]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
N
L
H
I
L
S
K
L
Q
E
E
---------
M
K
R
L
A
E
E
R
E
E
T
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
9.97
23%
21
- C2 -
-
3N00
-
B:
[1-21]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
H
R
L
I
T
L
A
D
H
---------
I
C
Q
I
I
T
Q
D
F
A
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
9.51
45%
-
- C2 -
-
2NSB
-
TIG_THEMA
A:
[40-60]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
-
I
P
G
F
R
K
G
R
I
P
K
N
V
L
K
M
K
--
L
G
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
9.00
7%
-35
- C2 -
-
2RDD
-
YAJC_ECOLI
B:
[17-30]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
F
M
I
L
R
P
Q
Q
K
R
T
K
E
-------------
22
Fugue
8.88
25%
258
* C2 *
-
1T01
-
B:
[1-24]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
R
P
L
L
Q
A
A
K
G
L
A
G
A
---------
V
S
E
L
L
R
S
A
Q
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
6.63
15%
-
- C2 -
-
5FU7
-
?
D:
[120-161]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
E
-----
I
A
R
S
L
K
I
F
A
Q
V
T
S
M
Q
D
V
---------
M
Q
E
F
A
T
N
G
Y
A
S
D
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------