@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3XZJ6: (2018-01-15 )
MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVSAFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTNVLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTAFIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKIIKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQSVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGMFMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGGVKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS
Atome Classification :
(20 SA)
-----------.........10........20........------------30...------.....40........50......---..60.-.---..----....70.....-...80........90.--.-.---.....100-----........110.......120.......130.......140---.-........150------.-.---.---.....-160.---..--....-------.----170---.-----...--------...-180.--...--...190...---------....200.-...-..--..-210-.........220.----......230..------------------.-..------..240---------...-----..----------------....250.......260-..----..-...-----.270..--.....280.......290.......300.......310..-.---.--...320.....--..330....-...340.......350...---------....360-----.......370..-.....380.......390----.-----.......400....----...410.......420.......430
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-----------MAI
E
A
G
L
V
L
F
F
V
F
V
V
L
L
VLGM
P
I
A
I
S
I
A
F
------------
S
S
M
M
T
------
L
L
L
V
IPFD
V
S
A
F
S
S
A
Q
K
M
V
GSIN---S
F
S
L
I
-
A
---
I
P
----
F
F
V
L
S
G
I
IMNN-G
G
I
A
K
K
L
V
D
F
A
M
L
F
V
G--R-V---PG
A
L
A
H
T
------
N
V
L
G
N
A
L
F
GSISS
S
A
I
AASTAIG
G
V
L
I
P
Q
Q
V
E
EGYDR
K
F
-----
A
-
T
A
V
NIASAPT-------
G
-
M
---
V
---IPP
S
T
-
A
-
F
I
---
M
Y
--
S
L
VA-------G----G
A
S
---
I
-----
S
A
L
--------
F
M
G
-
G
Y
L
V
--
G
A
L
--
W
A
L
G
I
M
L
V
A
---------
F
I
V
AKK-N-KYP-VV--EK-G---QM
A
H
A
G
K
I
I
K
E
A
I
----
P
S
L
L
L
I
V
I
I
I
G
------------------
G
-
I
L
------
T
G
I
-----------
F
T
A
-----
V
E
----------------
A
S
A
I
A
V
I
Y
S
L
L
I
A
M
F
Y
--
Y
K----TV-
K
L
K
-----
D
I
P
N
M
L
--
F
Q
S
V
AMS
G
T
I
M
F
L
LA
T
S
S
M
M
S
F
A
M
A
FTG
I
P
Q
A
I
S
S
L
I
MGV-T---D--NK
F
I
I
L
L
L
V
N
L
--
V
L
L
L
V
G
M
F
M
-
D
VA
P
A
I
L
I
F
T
P
I
F
L
P
I
V
T
S---------VGV
D
P
V
H
-----
Y
G
L
F
S
I
M
N
L
C
V
G-SITPPVGT
G
L
Y
V
GASVG-----G-----
V
K
A
E
A
M
L
K
P
L
L
P
F
Y
----
G
V
I
L
V
V
L
F
L
I
T
Y
F
P
Q
I
V
M
W
L
P
N
MLS-
30
Fugue
63.19
18%
-53
- C2 -
-
5ULM
-
M3K5_HUMAN
A:
[7-390]
-------------
F
R
E
S
I
L
N
D
I
R
K
A
R
N
L
Y
T
G
K
E
L
A
A
E
L
A
R
I
R
Q
R
V
D
N
IEVLT
A
D
I
V
I
------
N
L
L
L
S
Y
R
D
I
Q
D
Y
D
S
I
V
K
L
V
E
T
L
E
K
LP
T
F
D
L
A
-
S
H
H
H
V
K
----
F
H
Y
A
F
A
L
N
R
R
N
L
P
G
D
R
A
K
A
L
D
I
M
I
P
M
V
Q
--
Q
-
V
---
A
-------------
S
D
M
Y
C
L
V
G
R
I
Y
K
D
M
F
L
D
S
-
N
F
T
D
T
E
S
R
D
H
G
A
S
W
F
K
K
A
F
-----
E
-
S
E
P
T
L
Q
S
G
I
N
-------
Y
-
A
---
V
---
L
L
L
A
A
-
G
-
H
S
---
S
F
--
E
L
R
K
-------
V
----
G
V
K
---
L
-----
S
S
L
--------
L
G
K
K
G
N
L
E
KL
Q
S
Y
--
W
E
V
G
F
F
L
G
A
---------
S
V
L
A
N
D
-----------
H
M
-
R
---
V
I
Q
A
S
E
K
L
F
K
L
K
T
----
P
-------------------------------------------------------------
A
----------------
W
Y
L
K
S
I
V
E
T
I
L
I
Y
K
H
F
--
V
K
----
P
V
-
A
K
Q
-----
E
L
V
D
F
W
--
M
D
F
L
V
E
--------
A
T
K
T
--------------------
D
V
-
T
---
V
--
V
R
F
P
V
L
I
L
------------------
E
P
T
K
I
Y
Q
P
S
Y
L
S
I
N
N
E
---------
V
E
----------
E
K
T
I
S
I
W
H
V
L
P
D
-
D
-
K
K
G
I
H
E
W
N
F
S
A
S
S
V
R
-----
G
-----
V
S
I
S
K
F
E
E
R
C
C
F
L
Y
V
L
HN
S
D
D
F
Q
I
Y
F
C
T
E
L
H
C
K
K
F
F
E
M
V
N
T
I
T
E
17
HHSearch
61.14
13%
-145
- C2 -
-
5ULD
1
?
C:
[38-440]
----------------------
I
A
V
L
W
L
T
E
A
L
H
V
T
V
T
A
I
L
------------
V
P
V
M
A
------
V
F
F
G
I
---
F
E
----
T
Q
A
A
L
N
N
F
A
---
N
S
I
I
F
-
L
---
F
L
----
G
G
F
A
L
A
A
A
M
H
H
-
Q
G
L
D
K
V
I
A
D
K
V
L
A
M
A
Q
--
G
-
K
---
M
S
V
A
V
F
M
------
L
F
G
V
T
A
L
L
S
M
W
I
-
S
N
T
A
T
A
A
M
M
L
P
L
V
L
G
V
L
S
K
V
D
A
D
K
Q
R
STYVF
V
L
L
G
V
A
Y
S
A
S
I
G
-------
G
-
I
---
A
---
T
L
V
G
T
G
P
-
N
A
---
I
A
--
A
A
E
V
-------
G
-----
L
S
---
F
-----
T
D
W
--------
M
K
F
-
G
L
P
T
--
A
M
M
--
M
L
P
M
A
I
A
I
L
---------
Y
F
L
L
K
P
-
T
-
L
N
G
-
M
F
--
E
L
-
D
-----
R
A
P
V
N
W
D
K
G
K
V
----
V
T
L
G
I
F
G
L
T
V
F
------------------
L
W
I
F
------
S
S
P
-----------
I
N
A
ALGGF
K
S
F---------------
D
T
L
V
A
L
G
A
I
L
M
L
S
F
----
A
R
----
V
V
-
H
W
K
-----
E
I
Q
K
T
A
--
D
------
W
G
I
L
L
L
F
G
G
G
L
C
L
S
N
V
L
K
Q
T
G
T
S
V
F
L
A
N
A
L
S
D
M
V
S
H--
M
--
G
I
F
V
V
I
L
V
V
A
T
--
F
V
V
F
L
T
E
F
T
-
S
N
V
A
T
T
T
L
L
I
P
V
F
A
T
V
A
E
A
---------
F
G
M
S
P
V
L
-----
L
S
V
L
I
A
V
A
A
S
C
A
-
F
M
L
P
V
A
T
P
P
N
A
I
V
F
A
S
G
-----
H
-----
I
K
Q
S
E
M
M
R
V
G
L
Y
L
N
----
I
A
C
I
G
L
L
T
A
I
A
---------------
16
HHSearch
60.40
13%
-143
- C2 -
-
5ULE
1
?
C:
[38-440]
----------------------
I
A
V
L
W
L
T
E
A
L
H
V
T
V
T
A
I
L
------------
V
P
V
M
A
------
V
F
F
G
I
---
F
E
----
T
Q
A
A
L
N
N
F
A
---
N
S
I
I
F
-
L
---
F
L
----
G
G
F
A
L
A
A
A
M
H
H
-
Q
G
L
D
K
V
I
A
D
K
V
L
A
M
A
Q
--
G
-
K
---
M
S
V
A
V
F
M
------
L
F
G
V
T
A
L
L
S
M
W
I
-
S
N
T
A
T
A
A
M
M
L
P
L
V
L
G
V
L
S
K
V
D
A
D
K
Q
R
STYVF
V
L
L
G
V
A
Y
S
A
S
I
G
-------
G
-
I
---
A
---
T
L
V
G
T
G
P
-
N
A
---
I
A
--
A
A
E
V
-------
G
-----
L
S
---
F
-----
T
D
W
--------
M
K
F
-
G
L
P
T
--
A
M
M
--
M
L
P
M
A
I
A
I
L
---------
Y
F
L
L
K
P
-
T
-
L
N
G
-
M
F
--
E
L
-
D
-----
R
A
P
V
N
W
D
K
G
K
V
----
V
T
L
G
I
F
G
L
T
V
F
------------------
L
W
I
F
------
S
S
P
-----------
I
N
A
ALGGF
K
S
F---------------
D
T
L
V
A
L
G
A
I
L
M
L
S
F
----
A
R
----
V
V
-
H
W
K
-----
E
I
Q
K
T
A
--
D
------
W
G
I
L
L
L
F
G
G
G
L
C
L
S
N
V
L
K
Q
T
G
T
S
V
F
L
A
N
A
L
S
D
M
V
S
H--
M
--
G
I
F
V
V
I
L
V
V
A
T
--
F
V
V
F
L
T
E
F
T
-
S
N
V
A
T
T
T
L
L
I
P
V
F
A
T
V
A
E
A
---------
F
G
M
S
P
V
L
-----
L
S
V
L
I
A
V
A
A
S
C
A
-
F
M
L
P
V
A
T
P
P
N
A
I
V
F
A
S
G
-----
H
-----
I
K
Q
S
E
M
M
R
V
G
L
Y
L
N
----
I
A
C
I
G
L
L
T
A
I
A
---------------
28
Fugue
58.79
18%
-132
- C2 -
-
5DOQ
3
?
A:
[1-432]
MNGYDPV
L
L
S
R
I
L
T
E
L
T
L
T
V
H
I
I
Y
A
-
T
I
G
V
G
V
P
L
M
I
A
I
A
Q
------------
W
V
G
I
R
K
NDM
H
Y
I
L
L
A
R
R
W
T
R
G
F
V
I
T
V
A
V
G
V
V
T
G
T
---
A
I
G
L
Q
-
L
---
S
L
LW
P
N
F
M
Q
L
A
G
Q
V
I
S
----
L
P
L
F
M
E
T
F
A
F
F
F
E
A
--
I
-
F
---
L
G
I
Y
L
Y
T
W
DRFEN
Q
K
K
H
L
L
L
L
I
P
V
A
I
G
S
S
A
S
A
M
F
I
T
M
V
N
A
F
M
N
T
P
Q
G
F
E
L
K
N
-----
G
-
E
L
V
N
I
D
--
P
I
-------
V
-
A
---
M
---
F
N
P
A
M
-
P
-
T
K
---
V
A
--
H
V
L
A
-------
T
----
S
Y
M
---
T
-----
S
A
F
--------
V
L
A
-
S
I
A
A
--
W
H
L
--
W
---------------------
K
G
-
N
-
R
--------------------
H
I
Y
H
R
K
A
----
L
H
L
T
M
K
T
A
F
I
F
------------------
S
-
V
A
------
S
A
L
-----------
V
G
D
-----
L
S
----------------
G
K
F
L
A
E
Y
Q
P
E
K
L
A
A
A
E
--
W
H
----
F
E
-
T
S
S
-----
H
A
P
L
I
L
--
F
G
T
L
E
E
D
N
E
V
K
Y
A
L
E
I
P
Y
A
L
S
I
L
A
H
--
N
H
P
A
A
V
V
T
G
L
N
D
I
-
P
---
E
--
D
E
R
P
P
L
Y
I
H
Y
L
F
D
V
M
V
T
I
G
V
F
L
-
M
V
V
A
A
V
Y
W
L
G
S
I
F
R
W
K
W
T
A
KN
W
F
F
G
L
L
V
A
G
G
P
L
A
M
-----
I
A
I
E
A
G
W
Y
L
A
E
V
-
G
R
Q
P
W
I
L
R
G
Y
M
K
T
A
E
-------
G
-----
A
T
T
S
A
H
V
D
T
M
L
V
L
F
----
C
L
L
Y
I
V
L
V
I
A
S
A
T
V
L
I
R
M
F
R
R
N
P
---
19
HHSearch
53.94
11%
-154
- C2 -
-
4R0C
5
?
C:
[70-480]
-----------------------------------------------------------------------------
F
T
T
L
V
G
N
F
T
---
G
F
A
P
L
G
V
---
V
L
----
V
A
M
L
G
L
G
V
A
E
Q
-
S
G
L
L
S
V
S
L
A
S
L
V
R
R
S
S
--
G
-
G
---
A
L
-
V
--
F
------
T
V
A
F
A
G
V
L
S
S
L
-
T
V
-
D
A
G
Y
V
V
L
I
P
L
A
G
L
V
F
Q
L
A
G
R
P
P
I
A
-----
G
-
I
A
T
A
F
A
A
V
S
G
-------
G
-
F
SAN
L
---
L
V
G
P
V
-
D
-
A
T
L
A
G
L
S
--
T
E
A
A
H
I
IDPD
R
T
-----
V
A
---
A
-----
T
G
N
--------
Y
W
F
-
I
I
A
S
--
T
F
L
--
V
T
G
L
V
T
-
L
I
---------
T
R
T
L
T
E
-
P
R
L
A
H
A
N
T
--
V
A
D
A
SVD
A
P
Q
I
H
S
R
A
M
K
W
T
G
----
L
T
L
A
I
L
L
A
G
L
A
------------------
L
-
L
V
L-----
P
N
D
APLRHPDTGSV
L
G
S
-----
P
F
----------------
I
H
G
L
V
V
I
V
A
L
I
A
G
I
C
G
A
V
Y
G
R
V
S
G
Q
F
R
N
S
G
-----
A
V
I
T
A
M
--
E
V
T
M
A
S
M
A
G
Y
L
V
L
M
F
F
A
A
Q
F
V
A
W
F
N
Y
S
Q
L
G
L
L
L
A
V
K
G
A
A
W
L
G
A
L
T
V
--
P
K
V
V
L
L
L
L
F
V
V
--
L
T
A
L
I
N
L
M
I
G
S
A
S
A
K
W
S
I
L
A
P
V
F
I
P
M
L
M
L
---------
L
G
I
S
P
E
A
-----
S
Q
A
A
Y
R
V
G
D
S
S
T
N
I
I
T
P
L
M
P
-
Y
F
V
L
V
L
G
F
A
-----
R
R
YQPE
T
G
I
G
T
L
I
A
L
M
L
P
Y
S
----
L
T
L
L
L
G
W
S
V
L
L
---------------
18
HHSearch
51.79
11%
-151
- C2 -
-
4R0C
1
?
D:
[70-480]
-----------------------------------------------------------------------------
F
T
T
L
V
G
N
F
T
---
G
F
A
P
L
G
V
---
V
L
----
V
A
M
L
G
L
G
V
A
E
Q
-
S
G
L
L
S
V
S
L
A
S
L
V
R
R
S
S
--
G
-
G
---
A
L
-
V
--
F
------
T
V
A
F
A
G
V
L
S
S
L
-
T
V
-
D
A
G
Y
V
V
L
I
P
L
A
G
L
V
F
Q
L
A
G
R
P
P
I
A
-----
G
-
I
A
T
A
F
A
A
V
S
G
-------
G
-
F
SAN
L
---
L
V
G
P
V
-
D
-
A
T
L
A
G
L
S
--
T
E
A
A
H
I
IDPD
R
T
-----
V
A
---
A
-----
T
G
N
--------
Y
W
F
-
I
I
A
S
--
T
F
L
--
V
T
G
L
V
T
-
L
I
---------
T
R
T
L
T
E
-
P
R
L
A
H
A
N
T
--
V
A
D
A
SVD
A
P
Q
I
H
S
R
A
M
K
W
T
G
----
L
T
L
A
I
L
L
A
G
L
A
------------------
L
-
L
V
L-----
P
N
D
APLRHPDTGSV
L
G
S
-----
P
F
----------------
I
H
G
L
V
V
I
V
A
L
I
A
G
I
C
G
A
V
Y
G
R
V
S
G
Q
F
R
N
S
G
-----
A
V
I
T
A
M
--
E
V
T
M
A
S
M
A
G
Y
L
V
L
M
F
F
A
A
Q
F
V
A
W
F
N
Y
S
Q
L
G
L
L
L
A
V
K
G
A
A
W
L
G
A
L
T
V
--
P
K
V
V
L
L
L
L
F
V
V
--
L
T
A
L
I
N
L
M
I
G
S
A
S
A
K
W
S
I
L
A
P
V
F
I
P
M
L
M
L
---------
L
G
I
S
P
E
A
-----
S
Q
A
A
Y
R
V
G
D
S
S
T
N
I
I
T
P
L
M
P
-
Y
F
V
L
V
L
G
F
A
-----
R
R
Y
QPE
T
G
I
G
T
L
I
A
L
M
L
P
Y
S
----
L
T
L
L
L
G
W
S
V
L
L
---------------
20
HHSearch
51.00
12%
-
- C2 -
-
4R1I
-
?
A:
[84-499]
------------------------------------------------------------------------------
T
H
T
V
K
N
F
T
---
G
F
A
P
L
-
G
T
--
V
L
----
V
S
L
L
G
V
G
I
A
E
K
-
S
G
L
I
S
A
L
M
R
L
L
L
T
K
S
P
--
R
-
K
---
L
T
---
T
F
------
M
V
V
F
T
G
I
L
S
N
T
-
A
S
-
E
L
G
Y
V
V
L
I
P
L
S
A
V
I
F
H
S
L
G
R
H
P
L
A
-----
G
-
L
A
A
A
F
A
G
V
S
G
-------
G
-
Y
---
S
ANL
F
L
G
T
I
-
D
-
P
L
L
A
G
I
T
--
Q
Q
A
A
-------
Q
-----
I
I
HPD
Y
V
V
G
PE
A
N
W
--------
F
F
M
-
A
A
-
S
--
T
F
V
--
I
A
L
I
G
Y
F
V
T
---------
E
K
I
-
V
E
-
P
-
Q
L
G
P
Y
Q
SD
L
S
Q
E
E
K
-
D
I
R
H
S
N
E
I
T
P
L
E
Y
K
G
L
I
W
A
G
V
V
F
I
A
L
S
A
------------------
L
-
L
A
W
S
I
VPA
D
G
I
-----------
L
R
H
-----
P
E
TGLVAGSPFLKS
I
V
V
F
I
F
L
L
F
A
L
P
G
I
V
Y
G
R
I
T
--
R
S
----
L
R
-
G
E
R
-----
E
V
V
N
A
M
--
A
E
S
M
S
T
L
G
L
Y
L
V
I
I
F
F
A
A
Q
F
V
A
F
F
N
W
T
N
I
G
Q
Y
I
A
V
K
G
A
V
F
L
K
E
--
V
GL
A
G
S
V
L
F
I
G
F
I
L
--
I
C
A
F
I
N
L
M
I
G
S
A
S
A
Q
W
A
V
T
A
P
I
F
V
P
M
L
M
L
---------
A
G
Y
A
P
E
V
-----
I
Q
A
A
Y
R
I
G
D
S
V
T
-
N
I
I
T
P
M
M
S
Y
F
G
L
I
M
A
T
V
M
K
Y
KK
D
-----
A
G
V
G
T
L
I
S
M
M
L
P
Y
S
----
A
F
F
L
I
A
W
I
A
L
----------------
21
HHSearch
50.97
12%
-
- C2 -
-
4R1I
-
?
B:
[84-499]
------------------------------------------------------------------------------
T
H
T
V
K
N
F
T
---
G
F
A
P
L
-
G
T
--
V
L
----
V
S
L
L
G
V
G
I
A
E
K
-
S
G
L
I
S
A
L
M
R
L
L
L
T
K
S
P
--
R
-
K
---
L
T
---
T
F
------
M
V
V
F
T
G
I
L
S
N
T
-
A
S
-
E
L
G
Y
V
V
L
I
P
L
S
A
V
I
F
H
S
L
G
R
H
P
L
A
-----
G
-
L
A
A
A
F
A
G
V
S
G
-------
G
-
Y
---
S
ANL
F
L
G
T
I
-
D
-
P
L
L
A
G
I
T
--
Q
Q
A
A
-------
Q
-----
I
I
HPD
Y
VVGPE
A
N
W
--------
F
F
M
-
A
A
-
S
--
T
F
V
--
I
A
L
I
G
Y
F
V
T
---------
E
K
I
-
V
E
-
P
-
Q
L
G
P
Y
Q
SD
L
S
Q
E
E
K
-
D
I
R
H
S
N
E
I
T
P
L
E
Y
K
G
L
I
W
A
G
V
V
F
I
A
L
S
A
------------------
L
-
L
A
W
S
I
VPA
D
G
I
-----------
L
R
H
-----
P
E
TGLVAGSPFLKS
I
V
V
F
I
F
L
L
F
A
L
P
G
I
V
Y
G
R
I
T
--
R
S
----
L
R
-
G
E
R
-----
E
V
V
N
A
M
--
A
E
S
M
S
T
L
G
L
Y
L
V
I
I
F
F
A
A
Q
F
V
A
F
F
N
W
T
N
I
G
Q
Y
I
A
V
K
G
A
V
F
L
K
E
--
V
GL
A
G
S
V
L
F
I
G
F
I
L
--
I
C
A
F
I
N
L
M
I
G
S
A
S
A
Q
W
A
V
T
A
P
I
F
V
P
M
L
M
L
---------
A
G
Y
A
P
E
V
-----
I
Q
A
A
Y
R
I
G
D
S
V
T
-
N
I
I
T
P
M
M
S
Y
F
G
L
I
M
A
T
V
M
K
YKK
D
-----
A
G
V
G
T
L
I
S
M
M
L
P
Y
S
----
A
F
F
L
I
A
W
I
A
L
----------------
32
Fugue
42.94
18%
-388
- C2 -
-
1LYP
-
?
?:
[1-32]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
L
R
K
R
L
-
R
-
K
F
R
-
N
K
--
I
K
-
E
---
K
L
K
K
I
G
Q
K
I
Q
G
L
L
----
P
K
L
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
36.24
17%
-171
- C2 -
-
5ULD
1
?
C:
[64-218]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
----
I
F
-
E
T
Q
-----
A
A
L
N
N
F
--
A
------
N
S
I
I
F
L
F
L
G
G
F
A
L
A
A
A
M
H
H
Q
G
L
D
K
V
I
A
D
K
V
L
A
M
A
Q
---
G
--
K
M
S
V
A
V
F
M
L
F
G
--
V
T
A
L
L
S
M
W
I
-
S
N
T
A
T
A
A
M
M
L
P
L
V
L
G
V
L
S
K
---------
V
D
A
D
K
Q
R
STYVF
V
L
L
G
V
A
Y
S
A
S
I
G
G
I
A
T
L
V
G
T
G
P
N
A
I
A
A
A
E
V
-----
G
-----
L
S
F
T
D
W
M
K
F
G
L
P
T
A
----
M
M
M
L
P
M
A
I
A
I
----------------
23
HHSearch
35.84
17%
-171
* C2 *
-
5ULE
1
?
C:
[64-218]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
----
I
F
-
E
T
Q
-----
A
A
L
N
N
F
--
A
------
N
S
I
I
F
L
F
L
G
G
F
A
L
A
A
A
M
H
H
Q
G
L
D
K
V
I
A
D
K
V
L
A
M
A
Q
---
G
--
K
M
S
V
A
V
F
M
L
F
G
--
V
T
A
L
L
S
M
W
I
-
S
N
T
A
T
A
A
M
M
L
P
L
V
L
G
V
L
S
K
---------
V
D
A
D
K
Q
R
STYVF
V
L
L
G
V
A
Y
S
A
S
I
G
G
I
A
T
L
V
G
T
G
P
N
A
I
A
A
A
E
V
-----
G
-----
L
S
F
T
D
W
M
K
F
G
L
P
T
A
----
M
M
M
L
P
M
A
I
A
I
----------------
3
PsiBlast_PDB
34.89
24%
-131
- C2 -
-
4F4C
-
PGP1_CAEEL
A:
[224-449]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
T
-
G
F
I
V
--
A
F
T
H
S
W
Q
L
T
L
V
M
L
A
V
T
P
I
Q
A
L
C
G
F
A
I
A
K
S
M
S
-
T
F
A
-
I
R
--
E
T
-
L
---
R
Y
A
K
A
G
K
V
V
E
E
T
I
----
S
S
I
R
T
V
V
S
L
N
G
L
R
Y
E
L
E
R
Y
S
T
A
V
E
E
A
K
K
A
G
-
V
L
------
K
G
L
-----------
F
L
G
-----
I
S
----------------
F
G
A
M
Q
A
S
N
F
I
S
F
A
L
A
F
--
Y
I
----
G
V
-
G
W
V
H
D
GSL
N
F
G
D
M
L
T
T
F
S
S
V
M
M
-
G
S
M
A
L
G
L
A
G
P
Q
-----
L
A
V
L
G
T
A
Q
G
A
A
S
G
I
Y
E
V
-
L
---
D
--
R
K
P
V
I
-----------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
34.73
18%
-129
- C2 -
-
4R0C
-
?
C:
[343-479]
---------------------------------------------------------------------------------------------------------
F
A
A
Q
F
V
A
W
F
N
Y
-
S
Q
L
G
L
L
L
A
V
K
G
A
A
W
L
G
A
L
T
V
P
---
K
V
V
L
L
L
L
------
F
V
V
L
T
A
L
I
N
L
M
I
G
S
A
S
A
K
W
S
I
L
A
P
V
F
I
P
M
L
M
L
L
G
I
S
P
E
A
-----
S
-
Q
A
A
Y
R
V
G
D
S
S
-------
T
N
I
---
I
---
T
P
L
M
P
-
Y
-
F
V
---
L
V
--
L
G
F
A
-------
R
R
YQP
E
T
G
---
I
-----
G
T
L
--------
I
A
L
-
M
L
P
Y
--
S
L
T
--
L
L
L
G
W
S
V
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
34.31
18%
-129
- C2 -
-
4R0C
-
?
D:
[343-479]
---------------------------------------------------------------------------------------------------------
F
A
A
Q
F
V
A
W
F
N
Y
-
S
Q
L
G
L
L
L
A
V
K
G
A
A
W
L
G
A
L
T
V
P
---
K
V
V
L
L
L
L
------
F
V
V
L
T
A
L
I
N
L
M
I
G
S
A
S
A
K
W
S
I
L
A
P
V
F
I
P
M
L
M
L
L
G
I
S
P
E
A
-----
S
-
Q
A
A
Y
R
V
G
D
S
S
-------
T
N
I
---
I
---
T
P
L
M
P
-
Y
-
F
V
---
L
V
--
L
G
F
A
-------
R
R
Y
QP
E
T
G
---
I
-----
G
T
L
--------
I
A
L
-
M
L
P
Y
--
S
L
T
--
L
L
L
G
W
S
V
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
30.43
20%
-326
- C- -
-
5E79
-
PSBT_THEEB
T:
[1-30]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
----------------
T
I
T
Y
V
F
I
F
A
C
I
I
A
L
F
F
--
F
A
----
I
F
--
F
R
-----
E
P
P
R
I
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
29.90
28%
-247
- C2 -
-
1M45
-
B:
[1-25]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
I
S
Q
A
I
K
Y
L
Q
N
N
I
K
G
F
I
I
R
Q
R
V
N
D
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
25.36
15%
-
- C2 -
-
4R1I
-
?
A:
[359-500]
---------------------------------------------------------------------------------------------
V
-
I
---
I
F
----
F
A
A
Q
F
V
A
F
F
N
W
-
T
N
I
G
Q
Y
I
A
V
K
G
A
V
F
L
K
--
E
-
V
GLA
G
S
V
L
F
I
G
------
F
I
L
I
C
A
F
I
N
L
M
I
G
S
A
S
A
Q
W
A
V
T
A
P
I
F
V
P
M
L
M
L
A
G
Y
A
P
E
V
-----
I
-
Q
A
A
Y
R
I
G
D
S
V
-------
T
N
I
---
I
---
T
P
M
M
S
-
Y
F
G
L
---
I
M
A
T
V
M
K
Y
-------
K
K---
D
A
G
---
V
-----
G
T
L
--------
I
S
M
-
M
L
P
Y
--
S
A
F
--
F
L
I
A
W
I
A
L
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
25.16
33%
-177
- C1 -
-
3QUA
-
?
A:
[21-82]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Q
W
-----
A
-
V
C
V
Y
C
A
S
G
P
T
H
P
E
L
L
E
L
A
-
A
---
E
---
V
G
S
S
I
-
A
-
A
R
---
G
W
--
T
L
V
S
-------
G
----
G
G
N
---
V
-----
S
A
M
G
A
V
A
Q
A
A
R
A
K
G
-
G
H
T
V
--
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
25.11
15%
-
- C2 -
-
4R1I
-
?
B:
[359-500]
---------------------------------------------------------------------------------------------
V
-
I
---
I
F
----
F
A
A
Q
F
V
A
F
F
N
W
-
T
N
I
G
Q
Y
I
A
V
K
G
A
V
F
L
K
--
E
-
V
GLA
G
S
V
L
F
I
G
------
F
I
L
I
C
A
F
I
N
L
M
I
G
S
A
S
A
Q
W
A
V
T
A
P
I
F
V
P
M
L
M
L
A
G
Y
A
P
E
V
-----
I
-
Q
A
A
Y
R
I
G
D
S
V
-------
T
N
I
---
I
---
T
P
M
M
S
-
Y
F
G
L
---
I
M
A
T
V
M
K
Y
-------
K
K---
D
A
G
---
V
-----
G
T
L
--------
I
S
M
-
M
L
P
Y
--
S
A
F
--
F
L
I
A
W
I
A
L
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
23.38
36%
-297
- C2 -
-
3BXK
-
D:
[1-19]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
Y
A
A
M
M
I
M
E
Y
--
Y
R
----
Q
S
-
K
A
K
-----
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------