@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3Y331: (2018-02-03 )
MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTLTNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVRSHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGTKETVKVAVTYSGYEEQEDTRDYKHSRVE
Atome Classification :
(20 SA)
---------------------------------------------------------------------------------------------------.........10.....------------....20........30.....--...40...--.....--50........60...-----------------...---..70...-.....80........90........100.....-.--.110..-.-----------....120---------.......130..------.....140......-..150......-.160.......170.--------......180......----------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------------------------MNK
G
L
K
I
I
G
V
-
I
M
S
L
L
------------
L
L
S
V
F
L
A
I
A
L
INAPYI
M
P
E
Q
L
--
E
R
F
R
F
F
T
L
--
T
N
Y
Y
M
--
Q
Q
Y
I
F
W
A
A
V
V
F
A
V
L
A
-----------------
I
I
I
---
L
L
V
V
L
FY-PKSR
G
T
F
V
M
KRED
G
K
L
T
I
D
K
K
A
I
E
G
L
V
R
S
HL
H
E
-
E
--
E
FIHSP-
K
-----------
V
R
I
R
STK---------
N
R
I
H
I
H
VNG
D
L
K
------
R
T
S
S
L
V-GKT
G
V
L
M
-
Q
D
I
E
E
E
V
T
K
VL-GTK
E
T
V
K
V
A
V
T
YSGY--------EEQ
E
D
T
R
D
YKHSRVE----------------------------------------------------------------------------------------------------
43
Fugue
71.46
15%
-
- C4 -
-
5HM2
-
?
A:
[7-207]
----------------------------------------------------------------------------------------------D
L
Q
K
M
V
M
A
N
V
K
P
V
E
L
-
I
L
D
G
K
------------
T
V
A
L
C
C
A
T
G
V
F
G
T
A
Y
L
V
P
R
H
L
F
A
E
K
Y
D
K
V
V
L
--
D
G
R
Q
L
DN
S
D
F
R
V
F
E
F
E
V
K
V
K
G
Q
-----------------
D
M
M
S
D
A
A
L
M
V
L
N
R
-
G
Q
R
V
R
D
I
T
M
H
F
R
D
Q
V
H
I
K
K
G
T
P
V
L
G
V
I
N
N
A
-
D
V
-
G
--
R
L
I
F
S
G
-
D
-----------
A
L
T
Y
------------
K
D
V
V
V
A
M
D
G
D
T
M
PG
L
F
A
Y
R
A
G
T
K
V
-
G
Y
A
G
G
A
V
-
M
T
K
D
G
A
H
T
V
I
I
-
G
T
H
S
A
G
G
N
G
V
G
Y
C
S
C
--------
V
S
R
S
S
L
L
Q
L
K
-
A
H
I
D
----------------------------------------------------------------------------------------------------
41
Fugue
50.26
19%
-47
- C4 -
-
4PX7
2
?
A:
[1-258]
--------------------------------------------------------------------------------------------GR
S
I
A
R
R
T
A
V
G
A
A
L
L
L
V
M
P
V
A
V
W
I
SG
W
R
W
Q
P
GSW
L
L
K
A
A
F
W
V
T
E
T
V
T
Q
P
W
G
V
I
T
H
L
--
I
L
F
G
W
F
L
W
C
L
R
F
R
I
K
--
A
A
F
V
L
F
A
I
L
A
A
A
I
L
V
G
Q
G
V
K
S
W
IKDKVQEPR
P
F
V
I
---
W
L
E
K
T
H
H
M
P
V
D
K
F
Y
T
L
K
R
A
E
R
G
N
L
V
K
E
Q
L
A
E
P
Q
Y
L
R
S
H
W
Q
K
-
E
--
T
G
F
A
F
P
-
S
G
H
T
M
F
A
A
S
W
A
L
L
A
V
G
L
L
W
---------
P
R
R
R
T
L
T
I
A
I
L
L
------
V
W
A
T
G
V
M
G
S
R
L
L
L
G
M
H
W
P
R
D
L
V
V
A
T
L
-
I
S
W
A
L
V
A
V
A
T
W
L
A
Q
R
I
CGPLTPP
E
E
N
R
E
I
A
Q
R
E
Q
E
S
L
E
HH--------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
45.72
40%
-233
- C6 -
-
3JAV
-
ITPR1_RAT
A:
[2275-2299]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
W
S
S
I
S
F
N
L
A
V
-----------------
L
M
N
---
L
L
V
A
F
F
Y
-
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
42.28
27%
0
- C- -
-
5UGH
-
METK2_HUMAN
A:
[47-123]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
L
Q
Q
D
P
D
A
K
------
V
A
C
E
T
V
-
A
K
T
G
M
I
L
-
L
A
G
E
I
T
S
R
A
A
V
-
D
Y
Q
K
V
V
R
E
A
V
K
H
I
G
Y
--------
D
D
S
S
K
G
F
D
Y
K
T
C
N
V
-----------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
42.28
27%
0
- C- -
-
4KTV
2
METK2_HUMAN
A:
[46-126]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
L
Q
Q
D
P
D
A
K
------
V
A
C
E
T
V
-
A
K
T
G
M
I
L
-
L
A
G
E
I
T
S
R
A
A
V
-
D
Y
Q
K
V
V
R
E
A
V
K
H
I
G
Y
--------
D
D
S
S
K
G
F
D
Y
K
T
C
N
V
-----------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
42.28
27%
0
- C- -
-
4KTT
1
METK2_HUMAN
A:
[46-128]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
L
Q
Q
D
P
D
A
K
------
V
A
C
E
T
V
-
A
K
T
G
M
I
L
-
L
A
G
E
I
T
S
R
A
A
V
-
D
Y
Q
K
V
V
R
E
A
V
K
H
I
G
Y
--------
D
D
S
S
K
G
F
D
Y
K
T
C
N
V
-----------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
42.28
27%
0
- C- -
-
5A19
2
METK2_HUMAN
A:
[45-117]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
L
Q
Q
D
P
D
A
K
------
V
A
C
E
T
V
-
A
K
T
G
M
I
L
-
L
A
G
E
I
T
S
R
A
A
V
-
D
Y
Q
K
V
V
R
E
A
V
K
H
I
G
Y
--------
D
D
S
S
K
G
F
D
Y
K
T
C
N
V
-----------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
42.28
27%
0
- C- -
-
4NDN
3
METK2_HUMAN
A:
[45-125]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
L
Q
Q
D
P
D
A
K
------
V
A
C
E
T
V
-
A
K
T
G
M
I
L
-
L
A
G
E
I
T
S
R
A
A
V
-
D
Y
Q
K
V
V
R
E
A
V
K
H
I
G
Y
--------
D
D
S
S
K
G
F
D
Y
K
T
C
N
V
-----------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
41.73
33%
-
- C6 -
-
4A2W
-
?
A:
[436-544]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
I
Q
A
I
S
-
T
V
R
E
N
I
Q
E
L
Q
--
R
F
M
N
K
P
-
E
-----------
I
D
V
R
L
V
K
---------
R
R
I
H
---
N
P
F
A
A
------
I
I
S
N
L
M
-
S
E
T
E
A
L
M
-
R
T
I
---------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
41.72
18%
3
- C6 -
-
4OYC
-
PRGK_SALTY
B:
[106-183]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
S
A
I
E
Q
R
L
E
Q
S
L
Q
T
-
M
--
E
G
V
L
S
A
-
R
-----------
V
H
I
S
Y
D
I
DAP------
K
P
V
H
L
S
A
L
A
V
Y
E
------
R
G
S
P
L
A
-
H
Q
I
S
D
I
K
-----
R
F
L
K
N
S
F
A
D
V
-
D
Y
D
N
I
S
V
V
L
S
E
----------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
41.33
33%
-
- C6 -
-
4A2Q
-
?
A:
[436-545]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
I
Q
A
I
S
-
T
V
R
E
N
I
Q
E
L
Q
--
R
F
M
N
K
P
-
E
-----------
I
D
V
R
L
V
K
---------
R
R
I
H
---
N
P
F
A
A
------
I
I
S
N
L
M
-
S
E
T
E
A
L
M
-
R
T
I
---------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
40.98
13%
63
- C6 -
-
3J1Z
-
?
Q:
[513-592]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Q
R
I
K
L
I
A
K
E
-
D
--
P
R
V
L
G
L
H
D
-----------
L
R
T
R
Q
A
G
---------
K
T
V
F
I
Q
F
H
L
E
L
D
------
G
N
L
S
L
N
-
E
A
-
H
S
I
T
-
D
T
T
G
L
R
V
K
A
A
F
-
E
D
---
A
E
V
I
I
H
Q
D
P
V
--------
Q
V
E
P
T
T
Q
------------------------------------------------------------------------------------------------------------
38
HHSearch
39.93
15%
8
- C6 -
-
2OS5
-
?
A:
[16-105]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
A
N
F
E
E
R
L
T
D
L
L
A
E
-
S
--
M
N
K
P
R
N
-
R
-----------
I
A
I
E
V
L
A
G
Q
R
I
T
H
GAS
R
N
P
V
A
V
I
K
V
E
S
I
------
G
A
L
S
-
A
-
D
D
N
I
R
H
T
-
Q
K
I
T
Q
F
C
Q
D
T
L
-
K
L
-
P
K
D
K
V
I
I
T
Y
F
D
L
--------
Q
P
I
----------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
39.74
27%
-57
- C6 -
-
2P02
-
METK2_HUMAN
A:
[46-107]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
L
Q
Q
D
P
D
A
K
------
V
A
C
E
T
V
-
A
K
T
G
M
I
L
-
L
A
G
E
I
T
S
R
A
A
V
-
D
Y
Q
K
V
V
R
E
A
V
K
H
I
G
Y
--------
D
D
S
S
K
G
F
D
Y
K
T
C
N
V
-----------------------------------------------------------------------------------------------------
32
HHSearch
39.03
11%
-155
- C6 -
-
1YJ7
1
?
D:
[88-163]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
Y
L
K
E
Q
D
I
E
R
L
L
S
K
-
I
--
P
G
V
I
D
C
-
S
-----------
V
S
L
N
V
------------
P
S
S
A
A
V
L
V
I
S
S
------
P
E
V
N
L
A
-
P
S
V
I
-----
Q
I
K
N
L
V
K
N
S
V
-
D
D
L
K
L
E
N
I
S
V
V
I
------------------------------------------------------------------------------------------------------------------------------
47
Fugue
38.90
12%
-52
- C1 -
-
1W5C
-
PSBD_THEEB
D:
[1-350]
MTIAIG
R
A
P
A
E
RGWF
D
I
L
D
D
W
L
K
R
DRFVFVGWSGI
L
L
F
P
C
A
Y
L
A
L
G
G
W
L
T
G
T
TFVTSWYTHG
L
A
S
S
YLEGCNFLTVAVSTPANSMGHSLLLLWGPEAQG
D
F
T
R
W
C
Q
L
G
G
-
L
W
T
F
I
------------
A
L
H
G
A
F
G
L
I
G
F
M
L
R
Q
F
E
I
A
R
L
--
V
G
V
R
P
-----------------
Y
N
A
I
A
F
S
A
P
I
-----------------
A
V
F
---
V
S
V
F
L
I
Y
-
P
L
G
Q
S
S
W
---------------
F
F
A
P
S
F
G
V
A
A
I
-
F
--
R
F
L
L
F
F
-
Q
-----------
G
F
H
N
W
T
L
---------
N
P
F
H
M
M
G
V
A
G
V
L
------
G
G
A
L
L
C
-
A
I
H
G
A
T
V
-
E
N
T
----------
L
F
Q
D
G
E
G
A
S
T
F
R
A
F
--------
N
P
T
Q
A
E
E
T
Y
S
M
V
T
A
N
R
F
W
S
Q
I
FG
I
A
F
S
N
K
R
W
L
H
F
F
M
L
F
V
P
V
T
G
L
W
M
S
A
I
G
V
V
G
L
ALNLRSYDFISQ
E
I
R
A
A
E
D
P
EFETF
Y
T
K
N
L
L
L
N
E
G
I
R
A
W
M
APQDQPH
E
N
F
V
F
P
EEVLPRGN
19
HHSearch
38.62
9%
26
- C6 -
-
3H90
-
FIEF_ECOLI
B:
[207-281]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
Q
E
I
I
D
I
V
T
S
-
W
--
P
G
V
S
G
A
H
D
-----------
L
R
T
R
Q
S
G
---------
P
T
R
F
I
Q
I
H
L
E
M
E
------
D
S
L
P
L
V
-
Q
A
-
H
M
V
A
-
D
Q
V
E
Q
A
I
L
R
R
F
-
P
G
---
S
D
V
I
I
H
Q
D
P
C
--------
S
------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
38.48
27%
-54
- C6 -
-
5A1G
-
METK2_HUMAN
A:
[45-106]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
L
Q
Q
D
P
D
A
K
------
V
A
C
E
T
V
-
A
K
T
G
M
I
L
-
L
A
G
E
I
T
S
R
A
A
V
-
D
Y
Q
K
V
V
R
E
A
V
K
H
I
G
Y
--------
D
D
S
S
K
G
F
D
Y
K
T
C
N
V
-----------------------------------------------------------------------------------------------------
21
HHSearch
37.99
11%
58
- C6 -
-
3BYR
-
?
A:
[15-91]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
A
F
L
Q
E
-
R
I
R
G
R
A
L
E
V
H
D
-----------
L
K
T
R
R
A
G
---------
P
R
S
F
L
E
F
H
L
V
V
R
------
G
D
T
P
V
E
-
E
A
-
H
R
L
C
-
D
E
L
E
R
A
L
A
Q
A
F
-
P
G
---
L
Q
A
T
I
H
V
E
P
E
--------
G
E
R
K
R
--------------------------------------------------------------------------------------------------------------
34
HHSearch
37.51
16%
-101
* C6 *
-
5CLN
-
4OT1_PSEPU
C:
[5-49]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
H
I
L
------
E
G
R
S
-
D
-
E
Q
K
E
T
L
I
-
R
E
V
S
E
A
I
S
R
S
L
-
D
A
-
P
L
T
S
V
R
V
I
I
T
E
Y
--------
A
K
G
H
---------------------------------------------------------------------------------------------------------------