@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0278: (2016-03-14 )
LAQLSLEHIYKIYDNKVTAVSDFNLEIDDKEFIVFVGPSGCGKSTTLRMIAGLEEISKGELSIDGKVMNNVAPKDRDIAMVFQNYALYPHMTVYDNMAFGLKLRKMPKDEIKKRVEHAANILGLTEYLKRKPSALSGGQRQRVALGRAIVRDAKVFLMDEPLSNLDAKLRVQMRAEITKLHQQLDTTMIYVTHDQTEAMTMATRIVIMKDGVIQQVGSPKQVYDHPVNMFVAGFIGSPAMNFFKGRLEGSNFIGDDFTIEVPEGKLKLLKDRGFDGKNIVFGIRPEDIHDEPIVIEANPGYTFKATTIVAELTGAEFMLHSRVGTHEFVARVDARSEHQPNEVLTLAFEMSKSHFFDPETEDNLTD
Atome Classification :
(46 SA)
.........10....--....20........30........40........50........60....-...----.----70-----.---------------....-------..-.---------------.80........90.....-...100...---.....110.......120....-..-.130........140.......150.......160.......170.......180..---..---...190.......200.......210.......220.......230.......240.---.......250--..--.--.....260..-.....---270...---....280.......290..-...--.-.300.......--310.......320.....--..-330-.......340.......350.......360....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
LAQ
L
S
L
E
H
I
Y
K
I
YDN--
K
V
T
A
V
S
D
F
N
L
E
IDDK
E
F
I
V
F
VGPSGCGKS
T
T
L
R
M
I
A
G
L
E
E
ISKG
E
L
S
ID
G
-
K
V
M----N----N------V---------------APKD-------
R
D
-
I
---------------
A
M
V
F
Q
NYALYPH
M
T
V
YDN-MAF
G
-
L
K
LR---KM
P
K
D
E
I
K
K
R
V
E
H
A
A
N
I
L
G
L
T
E
-
Y
L
-
K
RK-PSALSGGQ
R
Q
R
V
A
L
G
R
A
I
VRD
A
K
V
F
L
MDEPLSNL
D
A
K
L
R
V
Q
M
R
A
E
I
T
K
L
H
Q
QL---D
T
---
T
M
I
Y
V
THDQT
E
A
M
T
M
A
T
R
I
V
I
MKD
G
V
I
Q
QVGSP
K
Q
V
Y
DH
P
V
N
M
F
V
A
G
FIG
S
P
A
M
-
N
F
---
F
K
GRLEGSN---FI--G--D
D
F
T
I
EVPEG-
K
L
K
L
L
---KDRGFD---GK
N
I
V
F
G
IRPEDIHDE
P
I
V
-
I
EA--N-PG
Y
T
F
K
A
T
T
I
V
--
A
ELTG
A
E
F
M
L
HSRVG
T
H
E
--
F
V
-
A
R
V-DARSEHQPN
E
V
L
T
L
A
F
EM
S
K
SHFFDPETEDNLTD
3
PsiBlast_PDB
95.02
51%
-111
- C2 -
2D62
8
?
A:
[5-371]
-
A
E
V
K
L
I
N
I
W
K
R
F
G
D
---
V
T
A
V
K
D
L
S
L
E
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
P
T
R
G
Q
I
Y
I
E
D
-
N
L
V
----
A
----
D
PEKG
V
F
V
---------------
P
P
K
E
-------
R
D
-
V
---------------
A
M
V
F
Q
S
Y
A
L
Y
P
H
M
T
V
Y
D
N
-
I
A
F
P
-
L
K
L
R
---
K
V
P
K
Q
E
I
D
K
R
V
R
E
V
A
E
M
L
G
L
T
E
-
L
L
-
N
R
K
-
P
R
E
L
S
G
G
Q
R
Q
R
V
A
L
G
R
A
I
I
R
R
P
K
V
F
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
K
M
R
A
E
L
K
K
L
Q
R
Q
L
---
G
V
---
T
T
I
Y
V
T
H
D
Q
V
E
A
M
T
M
G
D
R
I
A
V
M
N
K
G
E
L
Q
Q
V
G
T
P
D
E
V
Y
Y
K
P
V
N
T
F
V
A
G
F
I
G
S
P
P
M
-
N
F
---
L
D
A
T
I
T
D
D
G
---
F
L
--
D
F-
G
E
F
K
L
K
L
L
Q
D
-
Q
F
E
V
L
---
E
E
E
N
M
V
---
G
K
E
V
I
F
G
I
R
P
E
D
V
H
D
A
S
F
T
H
I
D
V
--
P
-
E
E
N
T
V
K
A
T
V
D
I
--
I
E
N
L
G
G
E
K
I
V
H
L
R
R
G
N
I
S
--
F
T
-
A
K
F
-
P
K
E
S
K
V
R
E
G
D
E
V
S
V
V
F
D
M
K
K
I
H
I
F
R
K
D
T
E
-----
1
PsiBlast_PDB
92.21
52%
-110
- C2 -
4TQU
-
?
S:
[2-362]
V
A
S
V
S
I
Q
N
V
V
K
R
Y
D
---
K
T
T
V
V
H
G
V
S
L
D
I
E
P
G
E
F
V
V
L
V
G
P
S
G
C
G
K
S
T
T
L
R
M
V
A
G
L
E
E
I
S
G
G
T
I
R
I
D
G
-
R
V
I
----
N
----
D
------
L
---------------
A
P
K
D
-------
R
D
-
V
---------------
A
M
V
F
Q
N
Y
A
L
Y
P
H
L
N
V
R
D
N
-
I
S
F
G
-
L
R
L
K
---
R
T
K
K
S
V
I
D
A
A
V
K
T
A
A
D
I
L
G
L
Q
P
-
L
L
-
E
R
K
-
P
S
D
L
S
G
G
Q
R
Q
R
V
A
M
G
R
A
I
V
R
D
P
K
V
F
L
F
D
Q
P
L
S
N
L
D
A
K
L
R
T
Q
M
R
A
E
I
K
R
L
H
Q
R
L
---
G
T
---
T
V
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
R
I
V
V
M
R
D
G
L
I
E
Q
I
G
K
P
M
D
L
F
L
H
P
A
N
T
F
V
A
S
F
I
G
S
P
P
M
-
N
L
---
M
P
A
R
I
A
-------
V
--
D
--
S
T
Q
H
V
E
L
N
G
G
N
R
I
S
L
L
---
P
R
A
G
T
H
LAP
G
Q
E
V
V
F
G
I
R
P
E
D
V
T
L
D
G
---
V
E
G
--
S
-
E
R
A
Q
I
K
A
T
V
D
I
--
V
E
P
L
G
S
E
S
I
L
H
A
T
V
G
D
H
S
--
L
V
-
V
K
V
-
G
G
L
N
E
V
H
P
G
D
P
V
T
L
H
V
D
L
T
R
V
H
L
F
D
A
Q
S
Q
A
S
I
--
2
PsiBlast_PDB
90.92
52%
-107
- C2 -
4TQV
-
?
C:
[2-362]
V
A
S
V
S
I
Q
N
V
V
K
R
Y
D
---
K
T
T
V
V
H
G
V
S
L
D
I
E
P
G
E
F
V
V
L
V
G
P
S
G
C
G
K
S
T
T
L
R
M
V
A
G
L
E
E
I
S
G
G
T
I
R
I
D
G
-
R
V
I
----
N
----
D
------
L
---------------
A
P
K
D
-------
R
D
-
V
---------------
A
M
V
F
Q
N
Y
A
L
Y
P
H
L
N
V
R
D
N
-
I
S
F
G
-
L
R
L
K
---
R
T
K
K
S
V
I
D
A
A
V
K
T
A
A
D
I
L
G
L
Q
P
-
L
L
-
E
R
K
-
P
S
D
L
S
G
G
Q
R
Q
R
V
A
M
G
R
A
I
V
R
D
P
K
V
F
L
F
D
Q
P
L
S
N
L
D
A
K
L
R
T
Q
M
R
A
E
I
K
R
L
H
Q
R
L
---
G
T
---
T
V
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
R
I
V
V
M
R
D
G
L
I
E
Q
I
G
K
P
M
D
L
F
L
H
P
A
N
T
F
V
A
S
F
I
G
S
P
P
M
-
N
L
---
M
P
A
R
I
A
-------
V
--
D
--
S
T
Q
H
V
E
L
N
G
G
N
R
I
S
L
L
---
P
R
A
G
T
H
LAP
G
Q
E
V
V
F
G
I
R
P
E
D
V
T
L
D
G
---
V
E
G
--
S
-
E
R
A
Q
I
K
A
T
V
D
I
--
V
E
P
L
G
S
E
S
I
L
H
A
T
V
G
D
H
S
--
L
V
-
V
K
V
-
G
G
L
N
E
V
H
P
G
D
P
V
T
L
H
V
D
L
T
R
V
H
L
F
D
A
Q
S
Q
A
S
I
--
4
PsiBlast_PDB
88.52
48%
-120
- C2 -
1V43
-
?
A:
[10-369]
M
V
E
V
K
L
E
N
L
T
K
R
F
G
N
---
F
T
A
V
N
K
L
N
L
T
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
P
T
E
G
R
I
Y
F
G
D
-
R
D
V
----
T
----
Y
------
L
---------------
P
P
K
D
-------
R
N
-
I
---------------
S
M
V
F
Q
------
H
M
T
V
Y
E
N
-
I
A
F
P
-
L
--
K
---
K
F
P
K
D
E
I
D
K
R
V
R
W
A
A
E
L
L
Q
I
E
E
-
L
L
-
N
R
Y
-
P
A
Q
L
S
G
G
Q
R
Q
R
V
A
V
A
R
A
I
V
V
E
P
D
V
L
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
A
M
R
A
E
I
K
K
L
Q
Q
K
L
---
K
V
---
T
T
I
Y
V
T
H
D
Q
V
E
A
M
T
M
G
D
R
I
A
V
M
N
R
G
Q
L
L
Q
I
G
S
P
T
E
V
Y
L
R
P
N
S
V
F
V
A
T
F
I
G
A
P
E
M
-
N
I
---
L
E
V
S
V
G
D
G
Y
---
L
E
--
G
--
R
G
F
R
I
E
L
P
Q
---
M
D
L
L
---
K
D
--
Y
V
---
G
K
T
V
L
F
G
I
R
P
E
H
M
T
V
E
G
V
-------
H
-
M
K
R
T
A
R
L
I
G
K
V
DF
V
E
A
L
G
T
D
T
I
L
H
V
K
F
G
D
E
L
--
V
K
-
V
K
L
-
P
G
H
I
P
I
E
P
G
R
E
V
K
V
I
M
D
L
D
M
I
H
V
F
D
K
D
T
E
-----
98
HHSearch
87.94
47%
-114
- C2 -
1V43
-
?
A:
[10-372]
M
V
E
V
K
L
E
N
L
T
K
R
F
G
---
N
F
T
A
V
N
K
L
N
L
T
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
P
T
E
G
R
I
Y
F
G
D
-
R
D
V
----
T
----
Y
------
L
---------------
P
P
K
D
-------
R
N
-
I
---------------
S
M
V
F
Q
------
H
M
T
V
Y
E
N
-
I
A
F
P
-
L
--
K
---
K
F
P
K
D
E
I
D
K
R
V
R
W
A
A
E
L
L
Q
I
E
E
-
L
L
-
N
R
Y
-
P
A
Q
L
S
G
G
Q
R
Q
R
V
A
V
A
R
A
I
V
V
E
P
D
V
L
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
A
M
R
A
E
I
K
K
L
Q
Q
K
L
---
K
V
---
T
T
I
Y
V
T
H
D
Q
V
E
A
M
T
M
G
D
R
I
A
V
M
N
R
G
Q
L
L
Q
I
G
S
P
T
E
V
Y
L
R
P
N
S
V
F
V
A
T
F
I
G
A
P
E
M
-
N
I
---
L
E
V
S
V
G
D
G
Y
---
L
E
--
G
--
R
G
F
R
I
E
L
P
Q
---
M
D
L
-----
L
K
D
Y
V
---
G
K
T
V
L
F
G
I
R
P
E
H
M
T
V
E
G
V
-----HM
K
-
R
T
A
R
L
I
G
K
V
D
F
--
V
E
A
L
G
T
D
T
I
L
H
V
K
F
G
D
E
L
--
V
K
-
V
K
L
-
P
G
H
I
P
I
E
P
G
R
E
V
K
V
I
M
D
L
D
M
I
H
V
F
D
K
D
T
E
K
A
I
--
5
PsiBlast_PDB
85.58
48%
-121
- C2 -
1VCI
1
?
A:
[10-369]
M
V
E
V
K
L
E
N
L
T
K
R
F
G
N
---
F
T
A
V
N
K
L
N
L
T
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
P
T
E
G
R
I
Y
F
G
D
-
R
D
V
----
T
----
Y
------
L
---------------
P
P
K
D
-------
R
N
-
I
---------------
S
M
V
F
Q
------
H
M
T
V
Y
E
N
-
I
A
F
P
-
L
--
K
---
K
F
P
K
D
E
I
D
K
R
V
R
W
A
A
E
L
L
Q
I
E
E
-
L
L
-
N
R
Y
-
P
A
Q
L
S
G
G
Q
R
Q
R
V
A
V
A
R
A
I
V
V
E
P
D
V
L
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
A
M
R
A
E
I
K
K
L
Q
Q
K
L
---
K
V
---
T
T
I
Y
V
T
H
D
Q
V
E
A
M
T
M
G
D
R
I
A
V
M
N
R
G
Q
L
L
Q
I
G
S
P
T
E
V
Y
L
R
P
N
S
V
F
V
A
T
F
I
G
A
P
E
M
-
N
I
---
L
E
V
S
V
G
D
G
Y
---
L
E
--
G
--
R
G
F
R
I
E
L
P
Q
---
M
D
L
L
---
K
D
--
Y
V
---
G
K
T
V
L
F
G
I
R
P
E
H
M
T
V
E
G
V
-------
H
-
M
K
R
T
A
R
L
I
G
K
V
DF
V
E
A
L
G
T
D
T
I
L
H
V
K
F
G
D
E
L
--
V
K
-
V
K
L
-
P
G
H
I
P
I
E
P
G
R
E
V
K
V
I
M
D
L
D
M
I
H
V
F
D
K
D
T
E
-----
102
HHSearch
83.63
44%
-98
- C2 -
3RLF
3
MALK_ECOLI
A:
[2-363]
-
A
S
V
Q
L
Q
N
V
T
K
A
W
G
---
E
V
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
-
K
R
M
----
N
----
D
------
T
---------------
P
P
A
E
-------
R
G
-
V
---------------
G
M
V
F
Q
S
Y
A
L
Y
P
H
L
S
V
A
E
N
-
M
S
F
G
-
L
K
L
A
---
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
-
L
L
-
D
R
K
-
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
---
G
R
---
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
P
K
M
-
N
F
---
L
P
V
K
V
T
A
T
A
---
I
D
--
Q
--
V
Q
V
E
L
P
M
P
N
R
-
Q
Q
V
W
L
PVE
S
R
D
V
Q
V
---
G
A
N
M
S
L
G
I
R
P
E
H
L
L
P
S
D
I
---------
A
D
V
I
L
E
G
E
V
Q
V
--
V
E
Q
L
G
N
E
T
Q
I
H
I
Q
I
P
S
I
R
Q
N
L
V
-
Y
R
Q
-
N
D
V
V
L
V
E
E
G
A
T
F
A
I
G
L
P
P
E
R
C
H
L
F
R
E
D
G
T
A
C
R
--
34
PsiBlast_CBE
81.46
45%
-103
- C2 -
2YYZ
3
?
A:
[10-358]
----------
K
K
Y
F
G
--
K
V
K
A
V
D
G
V
S
F
E
V
K
D
G
E
F
V
A
L
L
G
P
S
G
C
G
K
T
T
T
L
L
M
L
A
G
I
Y
K
P
T
S
G
E
I
Y
F
D
D
-
V
L
V
----
N
----
D
------
I
---------------
P
P
K
Y
-------
R
E
-
V
---------------
G
M
V
F
Q
N
Y
A
L
Y
P
H
M
T
V
F
E
N
-
I
A
F
P
-
L
R
A
R
---
R
I
S
K
D
E
V
E
K
R
V
V
E
I
A
R
K
L
L
I
D
N
-
L
L
-
D
R
K
-
P
T
Q
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
Q
P
K
V
L
L
F
D
E
P
L
S
N
L
D
A
N
L
R
M
I
M
R
A
E
I
K
H
L
Q
Q
E
L
---
G
I
---
T
S
V
Y
V
T
H
D
Q
A
E
A
M
T
M
A
S
R
I
A
V
F
N
Q
G
K
L
V
Q
Y
G
T
P
D
E
V
Y
D
S
P
K
N
M
F
V
A
S
F
I
G
N
P
P
T
-
N
F
L
R
D
F
S
V
S
V
E
N
K
Q
---
T
I
L
K
R
--
D
D
V
I
I
K
L
P
E
P
V
D
V
K
L
--------------
K
E
V
V
V
G
I
R
P
E
H
C
R
I
S
R
E
R
-
V
E
N
--
S
I
P
G
V
V
Y
-----
V
--
V
E
P
L
G
R
D
I
I
V
N
V
K
T
E
K
G
E
--
I
I
-
K
V
F
G
D
T
G
K
A
P
Q
P
G
E
N
V
F
L
V
P
D
L
R
K
I
H
L
F
N
P
E
T
E
E
T
I
--
101
HHSearch
81.22
45%
-104
- C2 -
2YYZ
3
?
A:
[2-358]
-
P
S
I
R
V
V
N
L
K
K
Y
F
G
---
K
V
K
A
V
D
G
V
S
F
E
V
K
D
G
E
F
V
A
L
L
G
P
S
G
C
G
K
T
T
T
L
L
M
L
A
G
I
Y
K
P
T
S
G
E
I
Y
F
D
D
-
V
L
V
----
N
----
D
------
I
---------------
P
P
K
Y
-------
R
E
-
V
---------------
G
M
V
F
Q
N
Y
A
L
Y
P
H
M
T
V
F
E
N
-
I
A
F
P
-
L
R
A
R
---
R
I
S
K
D
E
V
E
K
R
V
V
E
I
A
R
K
L
L
I
D
N
-
L
L
-
D
R
K
-
P
T
Q
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
Q
P
K
V
L
L
F
D
E
P
L
S
N
L
D
A
N
L
R
M
I
M
R
A
E
I
K
H
L
Q
Q
E
L
---
G
I
---
T
S
V
Y
V
T
H
D
Q
A
E
A
M
T
M
A
S
R
I
A
V
F
N
Q
G
K
L
V
Q
Y
G
T
P
D
E
V
Y
D
S
P
K
N
M
F
V
A
S
F
I
G
N
P
P
T
-
N
F
---
L
R
D
F
S
V
S
V
E
NK
Q
T
I
--
L
K
R
D
D
V
I
I
K
L
P
E
P
-----------
V
D
V
K
---
L
K
E
V
V
V
G
I
R
P
E
H
C
R
I
S
R
E
R
--------
V
E
N
S
I
P
G
V
V
Y
V
--
V
E
P
L
G
R
D
I
I
V
N
V
K
T
E
K
G
E
--
I
I
K
V
F
G
-
D
T
G
K
A
P
Q
P
G
E
N
V
F
L
V
P
D
L
R
K
I
H
L
F
N
P
E
T
E
E
T
I
--
99
HHSearch
81.20
39%
-99
- C2 -
2IT1
-
?
A:
[1-358]
M
V
E
I
K
L
E
N
I
V
K
K
F
G
---
N
F
T
A
L
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
Y
F
D
E
-
K
D
V
----
T
----
E
------
L
---------------
P
P
K
D
-------
R
N
-
V
---------------
G
L
V
F
Q
N
W
A
L
Y
P
H
M
T
V
Y
K
N
-
I
A
F
P
-
L
E
L
R
---
K
A
P
R
E
E
I
D
K
K
V
R
E
V
A
K
M
L
H
I
D
K
-
L
L
-
N
R
Y
-
P
W
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
K
R
L
Q
K
E
L
---
G
I
---
T
T
V
Y
V
T
H
D
Q
A
E
A
L
A
M
A
D
R
I
A
V
I
R
E
G
E
I
L
Q
V
G
T
P
D
E
V
Y
Y
K
P
K
Y
K
F
V
G
G
F
L
G
N
P
P
M
-
N
F
---
V
E
A
K
V
E
D
G
K
---
L
V
I-
T
--
E
K
S
K
L
P
I
P
K
Q
-
Y
V
-
E
----
I
V
K
E
T
G
---
I
T
E
V
I
I
G
F
R
P
H
D
A
E
I
V
K
G
---------
E
G
E
G
I
V
G
E
V
Y
S
--
F
E
P
L
G
R
E
Q
I
V
T
V
S
V
N
D
S
I
--
V
K
-
V
F
A
-
P
E
G
E
H
F
S
F
G
E
K
V
T
I
K
V
K
E
E
L
L
V
L
F
D
K
K
T
E
K
A
L
E
-
11
PsiBlast_PDB
79.89
51%
-106
- C2 -
3PUY
3
MALK_ECOLI
A:
[2-290]
-
A
S
V
Q
L
Q
N
V
T
K
A
W
-
G
--
E
V
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
-
K
R
M
----
N
----
D
------
T
---------------
P
P
A
E
-------
R
G
-
V
---------------
G
M
V
F
Q
S
Y
A
L
Y
P
H
L
S
V
A
E
N
-
M
S
F
G
-
L
K
L
A
---
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
-
L
L
-
D
R
K
-
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
---
G
R
---
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
P
K
M
-
N
F
---
L
P
V
K
V
T
A
T
A
---
I
D
--
Q
--
V
Q
V
E
L
P
M
P
N
R
-
Q
Q
V
W
L
---
P
V
E
S
R
D
VQV
G
A
N
M
S
L
G
I
R
P
E
H
L
----------------------------------------------------------------------------------------
17
PsiBlast_PDB
79.44
51%
-109
- C2 -
3RLF
3
MALK_ECOLI
A:
[2-290]
-
A
S
V
Q
L
Q
N
V
T
K
A
W
-
G
--
E
V
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
-
K
R
M
----
N
----
D
------
T
---------------
P
P
A
E
-------
R
G
-
V
---------------
G
M
V
F
Q
S
Y
A
L
Y
P
H
L
S
V
A
E
N
-
M
S
F
G
-
L
K
L
A
---
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
-
L
L
-
D
R
K
-
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
---
G
R
---
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
P
K
M
-
N
F
---
L
P
V
K
V
T
A
T
A
---
I
D
--
Q
--
V
Q
V
E
L
P
M
P
N
R
-
Q
Q
V
W
L
---
P
V
E
S
R
D
VQV
G
A
N
M
S
L
G
I
R
P
E
H
L
----------------------------------------------------------------------------------------
20
PsiBlast_PDB
78.84
51%
-108
- C2 -
4KI0
4
?
A:
[2-290]
-
A
S
V
Q
L
Q
N
V
T
K
A
W
-
G
--
E
V
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
-
K
R
M
----
N
----
D
------
T
---------------
P
P
A
E
-------
R
G
-
V
---------------
G
M
V
F
Q
S
Y
A
L
Y
P
H
L
S
V
A
E
N
-
M
S
F
G
-
L
K
L
A
---
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
-
L
L
-
D
R
K
-
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
---
G
R
---
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
P
K
M
-
N
F
---
L
P
V
K
V
T
A
T
A
---
I
D
--
Q
--
V
Q
V
E
L
P
M
P
N
R
-
Q
Q
V
W
L
---
P
V
E
S
R
D
VQV
G
A
N
M
S
L
G
I
R
P
E
H
L
----------------------------------------------------------------------------------------
16
PsiBlast_PDB
78.66
51%
-106
- C2 -
3PUX
5
MALK_ECOLI
A:
[2-290]
-
A
S
V
Q
L
Q
N
V
T
K
A
W
-
G
--
E
V
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
-
K
R
M
----
N
----
D
------
T
---------------
P
P
A
E
-------
R
G
-
V
---------------
G
M
V
F
Q
S
Y
A
L
Y
P
H
L
S
V
A
E
N
-
M
S
F
G
-
L
K
L
A
---
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
-
L
L
-
D
R
K
-
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
---
G
R
---
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
P
K
M
-
N
F
---
L
P
V
K
V
T
A
T
A
---
I
D
--
Q
--
V
Q
V
E
L
P
M
P
N
R
-
Q
Q
V
W
L
---
P
V
E
S
R
D
VQV
G
A
N
M
S
L
G
I
R
P
E
H
L
----------------------------------------------------------------------------------------
14
PsiBlast_PDB
78.62
51%
-106
- C2 -
3PUV
5
MALK_ECOLI
A:
[2-290]
-
A
S
V
Q
L
Q
N
V
T
K
A
W
-
G
--
E
V
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
-
K
R
M
----
N
----
D
------
T
---------------
P
P
A
E
-------
R
G
-
V
---------------
G
M
V
F
Q
S
Y
A
L
Y
P
H
L
S
V
A
E
N
-
M
S
F
G
-
L
K
L
A
---
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
-
L
L
-
D
R
K
-
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
---
G
R
---
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
P
K
M
-
N
F
---
L
P
V
K
V
T
A
T
A
---
I
D
--
Q
--
V
Q
V
E
L
P
M
P
N
R
-
Q
Q
V
W
L
---
P
V
E
S
R
D
VQV
G
A
N
M
S
L
G
I
R
P
E
H
L
----------------------------------------------------------------------------------------
15
PsiBlast_PDB
78.53
51%
-105
- C2 -
3PUW
5
MALK_ECOLI
A:
[2-290]
-
A
S
V
Q
L
Q
N
V
T
K
A
W
-
G
--
E
V
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
-
K
R
M
----
N
----
D
------
T
---------------
P
P
A
E
-------
R
G
-
V
---------------
G
M
V
F
Q
S
Y
A
L
Y
P
H
L
S
V
A
E
N
-
M
S
F
G
-
L
K
L
A
---
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
-
L
L
-
D
R
K
-
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
---
G
R
---
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
P
K
M
-
N
F
---
L
P
V
K
V
T
A
T
A
---
I
D
--
Q
--
V
Q
V
E
L
P
M
P
N
R
-
Q
Q
V
W
L
---
P
V
E
S
R
D
VQV
G
A
N
M
S
L
G
I
R
P
E
H
L
----------------------------------------------------------------------------------------
23
PsiBlast_CBE
78.32
51%
-107
- C2 -
3PUZ
2
MALK_ECOLI
B:
[2-290]
-
A
S
V
Q
L
Q
N
V
T
K
A
W
-
G
--
E
V
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
-
K
R
M
----
N
----
D
------
T
---------------
P
P
A
E
-------
R
G
-
V
---------------
G
M
V
F
Q
S
Y
A
L
Y
P
H
L
S
V
A
E
N
-
M
S
F
G
-
L
K
L
A
---
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
-
L
L
-
D
R
K
-
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
---
G
R
---
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
P
K
M
-
N
F
---
L
P
V
K
V
T
A
T
A
---
I
D
--
Q
--
V
Q
V
E
L
P
M
P
N
R
-
Q
Q
V
W
L
---
P
V
E
S
R
D
VQV
G
A
N
M
S
L
G
I
R
P
E
H
L
----------------------------------------------------------------------------------------
32
PsiBlast_CBE
78.07
51%
-107
- C2 -
2R6G
2
MALK_ECOLI (first)
B:
[2-290]
-
A
S
V
Q
L
Q
N
V
T
K
A
W
-
G
--
E
V
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
-
K
R
M
----
N
----
D
------
T
---------------
P
P
A
E
-------
R
G
-
V
---------------
G
M
V
F
Q
S
Y
A
L
Y
P
H
L
S
V
A
E
N
-
M
S
F
G
-
L
K
L
A
---
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
-
L
L
-
D
R
K
-
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
Q
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
---
G
R
---
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
P
K
M
-
N
F
---
L
P
V
K
V
T
A
T
A
---
I
D
--
Q
--
V
Q
V
E
L
P
M
P
N
R
-
Q
Q
V
W
L
---
P
V
E
S
R
D
VQV
G
A
N
M
S
L
G
I
R
P
E
H
L
----------------------------------------------------------------------------------------
12
PsiBlast_PDB
77.88
51%
-107
- C2 -
3PUZ
2
MALK_ECOLI
A:
[2-290]
-
A
S
V
Q
L
Q
N
V
T
K
A
W
-
G
--
E
V
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
-
K
R
M
----
N
----
D
------
T
---------------
P
P
A
E
-------
R
G
-
V
---------------
G
M
V
F
Q
S
Y
A
L
Y
P
H
L
S
V
A
E
N
-
M
S
F
G
-
L
K
L
A
---
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
-
L
L
-
D
R
K
-
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
---
G
R
---
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
P
K
M
-
N
F
---
L
P
V
K
V
T
A
T
A
---
I
D
--
Q
--
V
Q
V
E
L
P
M
P
N
R
-
Q
Q
V
W
L
---
P
V
E
S
R
D
VQV
G
A
N
M
S
L
G
I
R
P
E
H
L
----------------------------------------------------------------------------------------
33
PsiBlast_CBE
77.62
51%
-102
- C2 -
2R6G
2
MALK_ECOLI (first)
A:
[2-290]
-
A
S
V
Q
L
Q
N
V
T
K
A
W
-
G
--
E
V
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
-
K
R
M
----
N
----
D
------
T
---------------
P
P
A
E
-------
R
G
-
V
---------------
G
M
V
F
Q
S
Y
A
L
Y
P
H
L
S
V
A
E
N
-
M
S
F
G
-
L
K
L
A
---
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
-
L
L
-
D
R
K
-
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
Q
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
---
G
R
---
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
P
K
M
-
N
F
---
L
P
V
K
V
T
A
T
A
---
I
D
--
Q
--
V
Q
V
E
L
P
M
P
N
R
-
Q
Q
V
W
L
---
P
V
E
S
R
D
VQV
G
A
N
M
S
L
G
I
R
P
E
H
L
----------------------------------------------------------------------------------------
48
PsiBlast_CBE
63.34
37%
-116
- C2 -
3FVQ
3
FBPC_NEIG1
B:
[3-240]
-
A
A
L
H
I
G
H
L
S
K
S
F
Q
N
---
T
P
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
-
K
T
I
FSKN
T
----
N
------
L
---------------
P
V
R
E
-------
R
R
-
L
---------------
G
Y
L
V
Q
E
G
V
L
F
P
H
L
T
V
Y
R
N
-
I
A
Y
G
-
L
G
N
G
---
K
G
R
T
A
Q
E
R
Q
R
I
E
A
M
L
E
L
T
G
I
S
E
-
L
A
-
G
R
Y
-
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
---
G
K
---
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
P
A
D
L
D
A
A
L
F
I
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------
49
PsiBlast_CBE
63.14
37%
-113
- C2 -
3FVQ
3
FBPC_NEIG1
A:
[3-245]
-
A
A
L
H
I
G
H
L
S
K
S
F
Q
N
---
T
P
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
-
K
T
I
FSKN
T
----
N
------
L
---------------
P
V
R
E
-------
R
R
-
L
---------------
G
Y
L
V
Q
E
G
V
L
F
P
H
L
T
V
Y
R
N
-
I
A
Y
G
-
L
G
N
G
---
K
G
R
T
A
Q
E
R
Q
R
I
E
A
M
L
E
L
T
G
I
S
E
-
L
A
-
G
R
Y
-
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
---
G
K
---
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
P
A
D
L
D
A
A
L
F
I
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------
58
PsiBlast_CBE
58.09
33%
-104
- C2 -
4U00
3
?
A:
[5-229]
---
I
R
I
R
N
L
H
K
W
F
-
G
--
P
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
L
S
V
K
----
D
----
D
------
R
---------------
A
L
R
E
I
R
-----
R
E
-
V
---------------
G
M
V
F
Q
Q
F
N
L
F
P
H
M
T
V
L
E
N
-
V
T
L
A
P
M
R
V
R
---
R
W
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
L
D
-
Q
A
-
R
K
Y
-
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
D
V
M
R
D
L
A
Q
G
G
M
---
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
71
PsiBlast_CBE
57.11
35%
-100
- C2 -
2OLK
2
?
B:
[28-250]
-------
H
Q
L
K
K
S
F
G
--
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-
I
-----------
N
------
L
---------------
K
A
K
D
TNLNKVR
E
E
-
V
---------------
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
-
I
T
L
A
P
M
K
V
R
---
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
-
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
S
V
M
K
Q
L
---
A
N
EGM
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
81
PsiBlast_CBE
56.62
33%
-102
- C2 -
1L2T
4
Y796_METJA
B:
[11-225]
---------
Y
K
M
G
E
E
--
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
-
I
K
T
----
N
----
D
------
L
---------------
D
D
D
E
LTKIR--
R
D
K
I
---------------
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
-
V
E
L
P
-
L
I
F
K
YRG
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
F
A
-
N
H
K
-
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
---
G
K
---
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
111
HHSearch
56.57
32%
-100
- C2 -
2OLJ
4
?
A:
[22-260]
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
---
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-
I
N
L
----
K
----
A
------
K
DTN
L
-----------
N
K
V
R
-------
E
E
-
V
---------------
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
-
I
T
L
A
-
P
M
K
V
R--
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
-
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
---
G
M
---
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------
117
HHSearch
56.50
31%
-98
- C2 -
1B0U
4
HISP_SALTY
A:
[5-253]
-
N
K
L
H
V
I
D
L
H
K
R
Y
G
---
G
H
E
V
L
K
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
I
I
V
N
G
-
Q
N
I
----
N
----
L
------
V
R
D
KDGQLKVAD
K
N
Q
L
R
L
L
R
-------
T
R
-
L
---------------
T
M
V
F
Q
H
F
N
L
W
S
H
M
T
V
L
E
N
-
V
M
E
A
-
P
I
Q
V
L--
G
L
S
K
H
D
A
R
E
R
A
L
K
Y
L
A
K
V
G
I
D
E
-
R
A
Q
G
K
Y
-
P
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
R
I
M
Q
Q
L
A
E
-
E
---
G
K
---
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
Q
G
K
I
E
E
E
G
D
P
E
Q
V
F
G
N
P
Q
S
P
R
L
Q
Q
F
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------
75
PsiBlast_CBE
56.39
36%
-96
- C2 -
4YMV
1
?
J:
[7-224]
-----------
V
Y
K
N
FG
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
-
V
K
I
----
N
NGKV
N
------
I
---------------
N
K
V
R
-------
Q
K
-
V
---------------
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
-
I
T
L
A
P
V
K
V
K
---
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-
K
K
-
D
Q
Y
-
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
K
E
V
L
N
V
M
K
Q
L
---
A
N
EGM
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
74
PsiBlast_CBE
56.08
35%
-104
- C2 -
2OLJ
4
?
A:
[28-250]
-------
H
Q
L
K
K
S
F
G
--
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-
I
-----------
N
------
L
---------------
K
A
K
D
TN
L
N
K
V
R
E
E
-
V
---------------
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
-
I
T
L
A
P
M
K
V
R
---
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
-
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
S
V
M
K
Q
L
---
A
N
E
GM
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
62
PsiBlast_CBE
56.01
35%
-101
- C2 -
3C4J
3
?
A:
[28-250]
-------
H
Q
L
K
K
S
F
G
--
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-
I
-----------
N
------
L
---------------
K
A
K
D
TN
L
N
K
V
R
E
E
-
V
---------------
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
-
I
T
L
A
P
M
K
V
R
---
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
-
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
S
V
M
K
Q
L
---
A
N
E
GM
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
61
PsiBlast_CBE
55.98
35%
-103
- C2 -
3C4J
4
?
B:
[28-250]
-------
H
Q
L
K
K
S
F
G
--
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-
I
-----------
N
------
L
---------------
K
A
K
D
TNLNKVR
E
E
-
V
---------------
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
-
I
T
L
A
P
M
K
V
R
---
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
-
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
S
V
M
K
Q
L
---
A
N
EGM
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
84
PsiBlast_CBE
55.96
33%
-102
- C2 -
3TIF
7
Y796_METJA
A:
[11-225]
---------
Y
K
M
G
E
E
--
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
-
I
K
T
----
N
----
D
------
L
---------------
D
D
D
E
L
T
K
I
R
--
R
D
K
I
---------------
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
-
V
E
L
P
-
L
I
F
K
YR
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
F
A
-
N
H
K
-
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
---
G
K
---
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
76
PsiBlast_CBE
55.86
36%
-96
- C2 -
4YMV
1
?
A:
[7-224]
-----------
V
Y
K
N
FG
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
-
V
K
I
----
N
NGKV
N
------
I
---------------
N
K
V
R
-------
Q
K
-
V
---------------
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
-
I
T
L
A
P
V
K
V
K
---
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-
K
K
-
D
Q
Y
-
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
K
E
V
L
N
V
M
K
Q
L
---
A
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
69
PsiBlast_CBE
55.66
35%
-98
- C2 -
2OLK
1
?
D:
[28-250]
-------
H
Q
L
K
K
S
F
G
--
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-
I
-----------
N
------
L
---------------
K
A
K
D
TNLNKVR
E
E
-
V
---------------
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
-
I
T
L
A
P
M
K
V
R
---
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
-
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
S
V
M
K
Q
L
---
A
N
EGM
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
59
PsiBlast_CBE
55.59
35%
-103
- C2 -
3C41
3
?
K:
[7-229]
-------
H
Q
L
K
K
S
F
G
--
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-
I
-----------
N
------
L
---------------
K
A
K
D
TNLNKVR
E
E
-
V
---------------
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
-
I
T
L
A
P
M
K
V
R
---
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
-
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
S
V
M
K
Q
L
---
A
N
EGM
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
77
PsiBlast_CBE
55.41
36%
-97
- C2 -
4YMU
2
?
J:
[7-224]
-----------
V
Y
K
N
FG
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
-
V
K
I
----
N
NGKV
N
------
I
---------------
N
K
V
R
-------
Q
K
-
V
---------------
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
-
I
T
L
A
P
V
K
V
K
---
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-
K
K
-
D
Q
Y
-
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
K
E
V
L
N
V
M
K
Q
L
---
A
N
EGM
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
78
PsiBlast_CBE
55.38
36%
-98
- C2 -
4YMU
2
?
A:
[7-224]
-----------
V
Y
K
N
FG
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
-
V
K
I
----
N
NGKV
N
------
I
---------------
N
K
V
R
-------
Q
K
-
V
---------------
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
-
I
T
L
A
P
V
K
V
K
---
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-
K
K
-
D
Q
Y
-
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
K
E
V
L
N
V
M
K
Q
L
---
A
N
E
GM
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
83
PsiBlast_CBE
55.34
33%
-105
- C2 -
3TIF
7
Y796_METJA
B:
[11-225]
---------
Y
K
M
G
E
E
--
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
-
I
K
T
----
N
----
D
------
L
---------------
D
D
D
E
LTKIR--
R
D
K
I
---------------
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
-
V
E
L
P
-
L
I
F
K
YRG
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
F
A
-
N
H
K
-
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
---
G
K
---
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
70
PsiBlast_CBE
55.27
35%
-100
- C2 -
2OLK
1
?
C:
[28-250]
-------
H
Q
L
K
K
S
F
G
--
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-
I
-----------
N
------
L
---------------
K
A
K
D
TNLNKVR
E
E
-
V
---------------
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
-
I
T
L
A
P
M
K
V
R
---
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
-
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
S
V
M
K
Q
L
---
A
N
EGM
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
82
PsiBlast_CBE
55.23
33%
-102
- C2 -
1L2T
4
Y796_METJA
A:
[11-225]
---------
Y
K
M
G
E
E
--
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
-
I
K
T
----
N
----
D
------
L
---------------
D
D
D
E
L
T
K
I
R
--
R
D
K
I
---------------
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
-
V
E
L
P
-
L
I
F
K
YR
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
F
A
-
N
H
K
-
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
---
G
K
---
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
72
PsiBlast_CBE
55.04
35%
-100
- C2 -
2OLK
1
?
A:
[28-250]
-------
H
Q
L
K
K
S
F
G
--
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-
I
-----------
N
------
L
---------------
K
A
K
D
T
N
L
N
K
V
R
E
E
-
V
---------------
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
-
I
T
L
A
P
M
K
V
R
---
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
-
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
S
V
M
K
Q
L
---
A
N
E
GM
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
60
PsiBlast_CBE
54.56
35%
-96
- C2 -
3C41
3
?
J:
[7-229]
-------
H
Q
L
K
K
S
F
G
--
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-
I
-----------
N
------
L
---------------
K
A
K
D
TNLNKVR
E
E
-
V
---------------
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
-
I
T
L
A
P
M
K
V
R
---
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
-
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
S
V
M
K
Q
L
---
A
N
EGM
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
63
PsiBlast_CBE
54.04
35%
-101
- C2 -
2Q0H
4
?
B:
[28-250]
-------
H
Q
L
K
K
S
F
G
--
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-
I
-----------
N
------
L
---------------
K
A
K
D
TNL
N
K
V
R
E
E
-
V
---------------
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
-
I
T
L
A
P
M
K
V
R
---
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
-
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
S
V
M
K
Q
L
---
A
N
E
GM
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
73
PsiBlast_CBE
53.71
35%
-94
- C2 -
2OLJ
3
?
B:
[28-250]
-------
H
Q
L
K
K
S
F
G
--
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-
I
-----------
N
------
L
---------------
K
A
K
D
TNLNKVR
E
E
-
V
---------------
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
-
I
T
L
A
P
M
K
V
R
---
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
-
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
S
V
M
K
Q
L
---
A
N
EGM
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
64
PsiBlast_CBE
53.42
35%
-96
- C2 -
2Q0H
4
?
A:
[28-250]
-------
H
Q
L
K
K
S
F
G
--
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-
I
-----------
N
------
L
---------------
K
A
K
D
TN
L
N
K
V
R
E
E
-
V
---------------
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
-
I
T
L
A
P
M
K
V
R
---
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
-
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
S
V
M
K
Q
L
---
A
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
87
PsiBlast_CBE
45.16
32%
-79
- C2 -
1B0U
4
HISP_SALTY
A:
[45-258]
--------------------------------------------
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
I
I
V
N
G
-
Q
N
I
----
N
----
L
------
V
---------------
R
D
K
D
-------
G
Q
-
L
KVAD
K
N
Q
L
R
L
L
R
T
R
L
T
M
V
F
Q
H
F
N
L
W
S
H
M
T
V
L
E
N
V
M
E
A
P
-
I
Q
V
L
---
G
L
S
K
H
D
A
R
E
R
A
L
K
Y
L
A
K
V
G
I
D
E
-
R
A
-
Q
G
K
Y
P
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
----
V
G
E
V
L
R
I
M
Q
Q
L
A
E
E
G
K
---
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
Q
G
K
I
E
E
E
G
D
P
E
Q
V
F
G
N
P
---------
Q
S
P
R
L
Q
Q
F
---
L
K
G
S
L
K
----------------------------------------------------------------------------------------------------------------------------------------------