@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0490: (2016-03-16 )
MTNKITERITGHTELIGLIATPIRHSLSPTMHNEAFAKLGLDYVYLAFEVGDKELKDVVQGFRAMNLRGWNVSMPNKTNIHKYLDKLSPAAELVGAVNTVVNDDGVLTGHITDGTGYMRALKEAGHDIIGKKMTICGAGGAATAICIQAALDGVKEISIFNRKDDFYANAEKTVEKINSKTDCKAQLFDIEDHEQLRKEIAESVIFTNATGVGMKPFEGETLLPSADMLRPELIVSDVVYKPTKTRLLEIAEEQGCQTLNGLGMMLWQGAKAFEIWTHKEMPVDYIKEILF
Atome Classification :
(36 SA)
.........10.....-...20........30........40.......----.50........60........70........80........90........100--.--......110.......120..-.....-130.......140.....--..150.......160.......170......-.180.......190.......200.....-------------..210.......220.......230.......240.......250.......260.......270.......280.......290
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MT
N
K
I
T
E
R
ITG
H
T
E
L
I
-
G
L
I
A
T
P
I
R
H
SLSP
T
M
H
N
E
A
F
A
K
LGL
D
Y
V
Y
L
A
F
----EVG
D
K
E
L
K
D
V
V
Q
G
F
R
AMNLRGWNVSMPNK
T
N
I
H
K
Y
L
D
KLS
P
A
A
E
L
V
G
A
V
N
T
VVN--D--D
G
V
L
T
G
H
ITDG
T
G
Y
M
R
A
L
K
EA-
G
H
D
I
I-GK
K
M
T
I
CGAG
G
A
A
T
A
I
C
I
--
Q
A
A
LDG
V
K
E
I
S
I
FNRKDDFYA
N
A
E
K
T
V
E
K
IN-SKTDC
K
A
Q
L
F
DIE
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
FT-------------NATGVGMKPFEGETLLP
S
A
DMLR
P
E
L
I
V
S
D
VVYKP
T
K
T
R
L
L
E
I
A
E
EQGC
Q
T
L
N
G
L
G
M
M
L
WQG
A
K
A
F
E
I
W
THKEM
P
V
D
Y
I
K
E
ILF
30
PsiBlast_CBE
99.23
100%
-112
- C6 -
3TNL
2
AROE_LISMO
B:
[27-315]
--
N
K
I
T
E
R
I
T
G
H
T
E
L
I
-
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
----
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
--
D
--
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
-
G
H
D
I
I
-
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
--
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
D
D
F
Y
A
N
A
E
K
T
V
E
K
I
N
-
S
K
T
D
C
K
A
Q
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
-------------
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
F
1
PsiBlast_PDB
98.79
100%
-114
- C6 -
3TOZ
4
AROE_LISMO
A:
[25-315]
M
T
N
K
I
T
E
R
I
T
G
H
T
E
L
I
-
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
----
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
--
D
--
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
-
G
H
D
I
I
-
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
--
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
D
D
F
Y
A
N
A
E
K
T
V
E
K
I
N
-
S
K
T
D
C
K
A
Q
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
-------------
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
F
28
PsiBlast_CBE
98.78
100%
-114
- C6 -
3TNL
2
AROE_LISMO
D:
[28-315]
---
K
I
T
E
R
I
T
G
H
T
E
L
I
-
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
----
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
--
D
--
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
-
G
H
D
I
I
-
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
--
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
D
D
F
Y
A
N
A
E
K
T
V
E
K
I
N
-
S
K
T
D
C
K
A
Q
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
-------------
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
F
58
HHSearch
98.63
100%
-116
- C6 -
3TNL
3
AROE_LISMO
A:
[28-315]
---
K
I
T
E
R
I
T
G
H
T
E
L
I
-
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
----
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
--
D
--
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
-
G
H
D
I
I
-
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
--
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
D
D
F
Y
A
N
A
E
K
T
V
E
K
I
N
-
S
K
T
D
C
K
A
Q
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
-------------
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
F
2
PsiBlast_PDB
98.63
100%
-116
- C6 -
3TNL
3
AROE_LISMO
A:
[28-315]
---
K
I
T
E
R
I
T
G
H
T
E
L
I
-
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
----
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
--
D
--
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
-
G
H
D
I
I
-
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
--
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
D
D
F
Y
A
N
A
E
K
T
V
E
K
I
N
-
S
K
T
D
C
K
A
Q
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
-------------
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
F
25
PsiBlast_CBE
98.21
100%
-117
- C6 -
3TOZ
1
AROE_LISMO
D:
[27-315]
--
N
K
I
T
E
R
I
T
G
H
T
E
L
I
-
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
----
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
--
D
--
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
-
G
H
D
I
I
-
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
--
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
D
D
F
Y
A
N
A
E
K
T
V
E
K
I
N
-
S
K
T
D
C
K
A
Q
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
-------------
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
F
22
PsiBlast_CBE
98.18
100%
-113
- C6 -
3TOZ
2
AROE_LISMO
G:
[25-315]
M
T
N
K
I
T
E
R
I
T
G
H
T
E
L
I
-
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
----
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
--
D
--
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
-
G
H
D
I
I
-
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
--
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
D
D
F
Y
A
N
A
E
K
T
V
E
K
I
N
-
S
K
T
D
C
K
A
Q
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
-------------
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
F
29
PsiBlast_CBE
98.16
100%
-113
- C6 -
3TNL
3
AROE_LISMO
C:
[27-315]
--
N
K
I
T
E
R
I
T
G
H
T
E
L
I
-
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
----
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
--
D
--
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
-
G
H
D
I
I
-
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
--
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
D
D
F
Y
A
N
A
E
K
T
V
E
K
I
N
-
S
K
T
D
C
K
A
Q
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
-------------
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
F
27
PsiBlast_CBE
98.12
100%
-114
- C6 -
3TOZ
4
AROE_LISMO
B:
[26-315]
-
T
N
K
I
T
E
R
I
T
G
H
T
E
L
I
-
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
----
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
--
D
--
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
-
G
H
D
I
I
-
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
--
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
D
D
F
Y
A
N
A
E
K
T
V
E
K
I
N
-
S
K
T
D
C
K
A
Q
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
-------------
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
F
21
PsiBlast_CBE
97.93
100%
-112
- C6 -
3TOZ
3
AROE_LISMO
H:
[25-315]
M
T
N
K
I
T
E
R
I
T
G
H
T
E
L
I
-
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
----
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
--
D
--
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
-
G
H
D
I
I
-
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
--
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
D
D
F
Y
A
N
A
E
K
T
V
E
K
I
N
-
S
K
T
D
C
K
A
Q
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
-------------
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
F
24
PsiBlast_CBE
97.88
100%
-113
- C6 -
3TOZ
2
AROE_LISMO
E:
[27-315]
--
N
K
I
T
E
R
I
T
G
H
T
E
L
I
-
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
----
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
--
D
--
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
-
G
H
D
I
I
-
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
--
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
D
D
F
Y
A
N
A
E
K
T
V
E
K
I
N
-
S
K
T
D
C
K
A
Q
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
-------------
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
F
26
PsiBlast_CBE
97.86
100%
-114
- C6 -
3TOZ
3
AROE_LISMO
C:
[29-315]
----
I
T
E
R
I
T
G
H
T
E
L
I
-
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
----
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
--
D
--
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
-
G
H
D
I
I
-
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
--
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
D
D
F
Y
A
N
A
E
K
T
V
E
K
I
N
-
S
K
T
D
C
K
A
Q
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
-------------
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
F
23
PsiBlast_CBE
97.80
100%
-112
- C6 -
3TOZ
2
AROE_LISMO
F:
[29-315]
----
I
T
E
R
I
T
G
H
T
E
L
I
-
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
----
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
--
D
--
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
-
G
H
D
I
I
-
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
--
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
D
D
F
Y
A
N
A
E
K
T
V
E
K
I
N
-
S
K
T
D
C
K
A
Q
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
-------------
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
F
31
PsiBlast_CBE
84.83
51%
-104
- C6 -
3T4E
2
YDIB_SALTY
B:
[28-308]
---------
T
A
K
Y
E
L
I
-
G
L
M
A
Y
P
I
R
H
S
L
S
P
E
M
Q
N
K
A
L
E
K
A
G
L
P
Y
T
Y
M
A
F
----
E
V
D
N
T
T
F
A
S
A
I
E
G
L
K
A
L
K
M
R
G
T
G
V
S
M
P
N
K
Q
L
A
C
E
Y
V
D
E
L
T
P
A
A
K
L
V
G
A
I
N
T
I
V
N
--
D
--
D
G
Y
L
R
G
Y
N
T
D
G
T
G
H
I
R
A
I
K
E
S
-
G
F
D
M
R
-
G
K
T
M
V
L
L
G
A
G
G
A
A
T
A
I
G
A
--
Q
A
A
I
E
G
I
K
E
I
K
L
F
N
R
K
D
D
F
F
E
K
A
V
A
F
A
K
R
V
N
-
E
N
T
D
C
V
V
T
V
T
D
L
A
D
Q
H
A
F
T
E
A
L
A
S
A
D
I
L
T
-------------
N
G
T
K
V
G
M
K
P
L
E
N
E
S
L
I
G
D
V
S
L
L
R
P
E
L
L
V
T
E
C
V
Y
N
P
H
M
T
K
L
L
Q
Q
A
Q
Q
A
G
C
K
T
I
D
G
Y
G
M
L
L
W
Q
G
A
E
Q
F
E
L
W
T
G
K
A
F
P
L
D
Y
V
K
Q
V
M
-
59
HHSearch
84.21
51%
-103
- C6 -
3T4E
2
YDIB_SALTY
A:
[30-308]
-----------
K
Y
E
L
I
-
G
L
M
A
Y
P
I
R
H
S
L
S
P
E
M
Q
N
K
A
L
E
K
A
G
L
P
Y
T
Y
M
A
F
----
E
V
D
N
T
T
F
A
S
A
I
E
G
L
K
A
L
K
M
R
G
T
G
V
S
M
P
N
K
Q
L
A
C
E
Y
V
D
E
L
T
P
A
A
K
L
V
G
A
I
N
T
I
V
N
--
D
--
D
G
Y
L
R
G
Y
N
T
D
G
T
G
H
I
R
A
I
K
E
S
-
G
F
D
M
R
-
G
K
T
M
V
L
L
G
A
G
G
A
A
T
A
I
G
A
--
Q
A
A
I
E
G
I
K
E
I
K
L
F
N
R
K
D
D
F
F
E
K
A
V
A
F
A
K
R
V
N
-
E
N
T
D
C
V
V
T
V
T
D
L
A
D
Q
H
A
F
T
E
A
L
A
S
A
D
I
L
T
-------------
N
G
T
K
V
G
M
K
P
L
E
N
E
S
L
I
G
D
V
S
L
L
R
P
E
L
L
V
T
E
C
V
Y
N
P
H
M
T
K
L
L
Q
Q
A
Q
Q
A
G
C
K
T
I
D
G
Y
G
M
L
L
W
Q
G
A
E
Q
F
E
L
W
T
G
K
A
F
P
L
D
Y
V
K
Q
V
M
-
3
PsiBlast_PDB
84.21
51%
-103
- C6 -
3T4E
2
YDIB_SALTY
A:
[30-308]
-----------
K
Y
E
L
I
-
G
L
M
A
Y
P
I
R
H
S
L
S
P
E
M
Q
N
K
A
L
E
K
A
G
L
P
Y
T
Y
M
A
F
----
E
V
D
N
T
T
F
A
S
A
I
E
G
L
K
A
L
K
M
R
G
T
G
V
S
M
P
N
K
Q
L
A
C
E
Y
V
D
E
L
T
P
A
A
K
L
V
G
A
I
N
T
I
V
N
--
D
--
D
G
Y
L
R
G
Y
N
T
D
G
T
G
H
I
R
A
I
K
E
S
-
G
F
D
M
R
-
G
K
T
M
V
L
L
G
A
G
G
A
A
T
A
I
G
A
--
Q
A
A
I
E
G
I
K
E
I
K
L
F
N
R
K
D
D
F
F
E
K
A
V
A
F
A
K
R
V
N
-
E
N
T
D
C
V
V
T
V
T
D
L
A
D
Q
H
A
F
T
E
A
L
A
S
A
D
I
L
T
-------------
N
G
T
K
V
G
M
K
P
L
E
N
E
S
L
I
G
D
V
S
L
L
R
P
E
L
L
V
T
E
C
V
Y
N
P
H
M
T
K
L
L
Q
Q
A
Q
Q
A
G
C
K
T
I
D
G
Y
G
M
L
L
W
Q
G
A
E
Q
F
E
L
W
T
G
K
A
F
P
L
D
Y
V
K
Q
V
M
-
4
PsiBlast_PDB
82.73
47%
-108
- C6 -
1VI2
2
YDIB_ECOLI
A:
[7-285]
----------
A
K
Y
E
L
I
-
G
L
M
A
Y
P
I
R
H
S
L
S
P
E
M
Q
N
K
A
L
E
K
A
G
L
P
F
T
Y
M
A
F
----
E
V
D
N
D
S
F
P
G
A
I
E
G
L
K
A
L
K
M
R
G
T
G
V
S
M
P
N
K
Q
L
A
C
E
Y
V
D
E
L
T
P
A
A
K
L
V
G
A
I
N
T
I
V
N
--
D
--
D
G
Y
L
R
G
Y
N
T
D
G
T
G
H
I
R
A
I
K
E
S
-
G
F
D
I
K
-
G
K
T
M
V
L
L
G
A
G
G
A
S
T
A
I
G
A
--
Q
G
A
I
E
G
L
K
E
I
K
L
F
N
R
R
D
E
F
F
D
K
A
L
A
F
A
Q
R
V
N
-
E
N
T
D
C
V
V
T
V
T
D
L
A
D
Q
Q
A
F
A
E
A
L
A
S
A
D
I
L
T
-------------
N
G
T
K
V
G
M
K
P
L
E
N
E
S
L
V
N
D
I
S
L
L
H
P
G
L
L
V
T
E
C
V
Y
N
P
H
M
T
K
L
L
Q
Q
A
Q
Q
A
G
C
K
T
I
D
G
Y
G
M
L
L
W
Q
G
A
E
Q
F
T
L
W
T
G
K
D
F
P
L
E
Y
V
K
Q
V
--
5
PsiBlast_PDB
82.18
47%
-97
- C6 -
1NPD
1
YDIB_ECOLI
A:
[3-283]
--------
V
T
A
K
Y
E
L
I
-
G
L
M
A
Y
P
I
R
H
S
L
S
P
E
M
Q
N
K
A
L
E
K
A
G
L
P
F
T
Y
M
A
F
----
E
V
D
N
D
S
F
P
G
A
I
E
G
L
K
A
L
K
M
R
G
T
G
V
S
M
P
N
K
Q
L
A
C
E
Y
V
D
E
L
T
P
A
A
K
L
V
G
A
I
N
T
I
V
N
--
D
--
D
G
Y
L
R
G
Y
N
T
D
G
T
G
H
I
R
A
I
K
E
S
-
G
F
D
I
K
-
G
K
T
M
V
L
L
G
A
G
G
A
S
T
A
I
G
A
--
Q
G
A
I
E
G
L
K
E
I
K
L
F
N
R
R
D
E
F
F
D
K
A
L
A
F
A
Q
R
V
N
-
E
N
T
D
C
V
V
T
V
T
D
L
A
D
Q
Q
A
F
A
E
A
L
A
S
A
D
I
L
T
-------------
N
G
T
K
V
G
M
K
P
L
E
N
E
S
L
V
N
D
I
S
L
L
H
P
G
L
L
V
T
E
C
V
Y
N
P
H
M
T
K
L
L
Q
Q
A
Q
Q
A
G
C
K
T
I
D
G
Y
G
M
L
L
W
Q
G
A
E
Q
F
T
L
W
T
G
K
D
F
P
L
E
Y
V
K
Q
V
--
6
PsiBlast_PDB
81.36
47%
-106
- C6 -
1O9B
4
YDIB_ECOLI
A:
[7-283]
------------
Y
E
L
I
-
G
L
M
A
Y
P
I
R
H
S
L
S
P
E
M
Q
N
K
A
L
E
K
A
G
L
P
F
T
Y
M
A
F
----
E
V
D
N
D
S
F
P
G
A
I
E
G
L
K
A
L
K
M
R
G
T
G
V
S
M
P
N
K
Q
L
A
C
E
Y
V
D
E
L
T
P
A
A
K
L
V
G
A
I
N
T
I
V
N
--
D
--
D
G
Y
L
R
G
Y
N
T
D
G
T
G
H
I
R
A
I
K
E
S
-
G
F
D
I
K
-
G
K
T
M
V
L
L
G
A
G
G
A
S
T
A
I
G
A
--
Q
G
A
I
E
G
L
K
E
I
K
L
F
N
R
R
D
E
F
F
D
K
A
L
A
F
A
Q
R
V
N
-
E
N
T
D
C
V
V
T
V
T
D
L
A
D
Q
Q
A
F
A
E
A
L
A
S
A
D
I
L
T
-------------
N
G
T
K
V
G
M
K
P
L
E
N
E
S
L
V
N
D
I
S
L
L
H
P
G
L
L
V
T
E
C
V
Y
N
P
H
M
T
K
L
L
Q
Q
A
Q
Q
A
G
C
K
T
I
D
G
Y
G
M
L
L
W
Q
G
A
E
Q
F
T
L
W
T
G
K
D
F
P
L
E
Y
V
K
Q
V
--
8
PsiBlast_PDB
73.48
37%
-85
- C6 -
2EGG
2
AROE_GEOKA
A:
[20-292]
----------
G
H
M
E
K
V
Y
G
L
I
G
F
P
V
E
H
S
L
S
P
L
M
H
N
D
A
F
A
R
L
G
I
P
A
R
Y
H
L
F
----
S
V
E
P
G
Q
V
G
A
A
I
A
G
V
R
A
L
G
I
A
G
V
N
V
T
I
P
H
K
L
A
V
I
P
F
L
D
E
V
D
E
H
A
R
R
I
G
A
V
N
T
I
I
N
--
N
--
D
G
R
L
V
G
Y
N
T
D
G
L
G
Y
V
Q
A
L
E
E
E
-
M
N
I
T
L
D
G
K
R
I
L
V
I
G
A
G
G
G
A
R
G
I
Y
F
--
S
L
L
S
T
A
A
E
R
I
D
M
A
N
R
------
T
V
E
K
A
E
R
L
V
R
-
E
G
D
E
R
R
S
A
Y
F
S
L
A
E
A
E
---
T
R
L
A
E
Y
D
I
I
I
-------------
N
T
T
S
V
G
M
H
P
-
R
V
E
V
Q
P
L
S
L
E
R
L
R
P
G
V
I
V
S
D
I
I
Y
N
P
L
E
T
K
W
L
K
E
A
K
A
R
G
A
R
V
Q
N
G
V
G
M
L
V
Y
Q
G
A
L
A
F
E
K
W
T
G
Q
W
P
D
V
N
R
M
K
Q
L
V
I
61
HHSearch
71.80
40%
-89
- C6 -
1NVT
2
AROE_METJA
A:
[4-281]
-----
G
S
M
I
N
A
K
T
K
V
I
-
G
L
I
G
H
P
V
E
H
S
F
S
P
I
M
H
N
A
A
F
K
D
K
G
L
N
Y
V
Y
V
A
F
----
D
V
L
P
E
N
L
K
Y
V
I
D
G
A
K
A
L
G
I
V
G
F
N
V
T
I
P
H
K
I
E
I
M
K
Y
L
D
E
I
D
K
D
A
Q
L
I
G
A
V
N
T
I
K
I
--
E
--
D
G
K
A
I
G
Y
N
T
D
G
I
G
A
R
M
A
L
E
E
E
-
I
G
R
V
K
-
D
K
N
I
V
I
Y
G
A
G
G
A
A
R
A
V
A
F
--
E
L
A
K
D
N
--
N
I
I
I
A
N
R
T
V
E
---
K
A
E
A
L
A
K
E
I
A
-
E
K
L
N
K
K
F
--
G
E
E
V
K
F
S
G
L
D
V
D
L
D
G
V
D
I
I
I
-------------
N
A
T
P
I
G
M
Y
P
N
I
D
V
E
P
I
V
K
A
E
K
L
R
E
D
M
V
V
M
D
L
I
Y
N
P
L
E
T
V
L
L
K
E
A
K
K
V
N
A
K
T
I
N
G
L
G
M
L
I
Y
Q
G
A
V
A
F
K
I
W
T
G
V
E
P
N
I
E
V
M
K
N
A
I
-
73
HHSearch
71.71
35%
-91
- C6 -
2HK9
3
AROE_AQUAE
A:
[7-270]
-------
M
I
N
A
Q
T
Q
L
Y
-
G
V
I
G
F
P
V
K
H
S
L
S
P
V
F
Q
N
A
L
I
R
Y
A
G
L
N
A
V
Y
L
A
F
----
E
I
N
P
E
E
L
K
K
A
F
E
G
F
K
A
L
K
V
K
G
I
N
V
T
V
P
F
K
E
E
I
I
P
L
L
D
Y
V
E
D
T
A
K
E
I
G
A
V
N
T
V
K
F
--
E
--
N
G
K
A
Y
G
Y
N
T
D
W
I
G
F
L
K
S
L
K
S
L
-
I
P
E
V
K
-
E
K
S
I
L
V
L
G
A
G
G
A
S
R
A
V
I
Y
--
A
L
V
K
E
G
A
-
K
V
F
L
W
N
R
T
K
E
---
K
A
I
K
L
A
Q
K
F
P
-
L
E
V
-----------
V
N
S
P
E
E
V
I
D
K
V
Q
V
I
V
-------------
N
T
T
S
V
G
L
K
D
E
D
P
E
--
I
F
N
Y
D
L
I
K
K
D
H
V
V
V
D
I
I
Y
K
--
E
T
K
L
L
K
K
A
K
E
K
G
A
K
L
L
D
G
L
P
M
L
L
W
Q
G
I
E
A
F
K
I
W
N
G
C
E
V
P
Y
S
V
A
E
R
S
V
-
69
HHSearch
71.56
33%
-92
- C6 -
2O7S
2
DHQSD_ARATH
A:
[228-511]
------
R
R
I
G
P
D
T
K
V
Y
-
G
I
I
G
K
P
V
S
H
S
K
S
P
I
V
H
N
Q
A
F
K
S
V
D
F
N
G
V
Y
V
H
L
----
L
V
D
--
N
L
V
S
F
L
Q
A
Y
S
S
S
D
F
A
G
F
S
C
T
I
P
H
K
E
A
A
L
Q
C
C
D
E
V
D
P
L
A
K
S
I
G
A
V
N
T
I
L
R
--
R
KS
D
G
K
L
L
G
Y
N
T
D
C
I
G
S
I
S
A
I
E
D
G
-
L
-------
T
V
V
V
I
G
A
G
G
A
G
K
A
L
A
Y
--
G
A
K
E
K
G
A
--
V
V
I
A
N
R
T
Y
E
---
R
A
L
E
L
A
E
A
I
G
-
G
-------
A
L
S
L
T
D
L
D
N
Y
----
E
D
G
M
V
L
A
-------------
N
T
T
S
M
G
M
Q
P
N
V
E
E
T
P
-
I
S
K
D
A
L
K
H
Y
A
L
V
F
D
A
V
Y
T
P
R
I
T
R
L
L
R
E
A
E
E
S
G
A
I
T
V
S
G
S
E
M
F
V
R
Q
A
Y
E
Q
F
E
I
F
T
G
L
P
A
P
K
E
L
Y
W
Q
I
M
-
20
PsiBlast_PDB
71.24
30%
-93
- C6 -
2O7Q
3
DHQSD_ARATH
A:
[228-511]
------
R
R
I
G
P
D
T
K
V
Y
-
G
I
I
G
K
P
V
S
H
S
K
S
P
I
V
H
N
Q
A
F
K
S
V
D
F
N
G
V
Y
V
H
L
----
L
V
D
N
--
L
V
S
F
L
Q
A
Y
S
S
S
D
F
A
G
F
S
C
T
I
P
H
K
E
A
A
L
Q
C
C
D
E
V
D
P
L
A
K
S
I
G
A
V
N
T
I
L
R
RK
S
--
D
G
K
L
L
G
Y
N
T
D
C
I
G
S
I
S
A
I
E
D
G
L
--------
T
V
V
V
I
G
A
G
G
A
G
K
A
L
A
Y
--
G
A
K
E
K
-
A
K
-
V
V
I
A
N
R
T
---
Y
E
R
A
L
E
L
A
E
A
I
G
-
G
K
A
---
L
S
L
T
D
L
D
N
Y
-------
E
D
G
M
V
L
A
-------------
N
T
T
S
M
G
M
Q
P
N
V
E
E
T
P
I
-
S
K
D
A
L
K
H
Y
A
L
V
F
D
A
V
Y
T
P
R
I
T
R
L
L
R
E
A
E
E
S
G
A
I
T
V
S
G
S
E
M
F
V
R
Q
A
Y
E
Q
F
E
I
F
T
G
L
P
A
P
K
E
L
Y
W
Q
I
M
-
13
PsiBlast_PDB
70.64
34%
-91
- C6 -
3DOO
1
AROE_STAEQ
A:
[4-262]
-----------------
A
V
I
G
N
P
I
S
H
S
L
S
P
L
M
H
H
A
N
F
Q
S
L
N
L
E
N
T
Y
E
A
I
----
N
V
P
V
N
Q
F
Q
D
I
K
K
I
I
S
E
K
S
I
D
G
F
N
V
T
I
P
H
K
E
R
I
I
P
Y
L
D
D
I
N
E
Q
A
K
S
V
G
A
V
N
T
V
L
V
--
K
--
D
G
K
W
I
G
Y
N
T
D
G
I
G
Y
V
N
G
L
K
Q
I
-
Y
E
G
I
E
-
D
A
Y
I
L
I
L
G
A
G
G
A
S
K
G
I
A
N
--
E
L
Y
K
I
V
R
P
T
L
T
V
A
N
R
T
M
S
R
F
N
N
W
S
L
N
I
N
K
I
N
L
S
H
A
E
S
H
L
D
E
F
D
---------------
I
I
I
-------------
N
T
T
P
---------
V
I
--
S
L
N
R
L
A
S
H
T
L
V
S
D
I
V
Y
N
P
Y
K
T
P
I
L
I
E
A
E
Q
R
G
N
P
I
Y
N
G
L
D
M
F
V
H
Q
G
A
E
S
F
K
I
W
T
N
L
E
P
D
I
K
A
M
K
N
I
V
I
11
PsiBlast_PDB
69.75
35%
-92
- C6 -
2HK9
3
AROE_AQUAE
A:
[8-262]
--------
I
N
A
Q
T
Q
L
Y
-
G
V
I
G
F
P
V
K
H
S
L
S
P
V
F
Q
N
A
L
I
R
Y
A
G
L
N
A
V
Y
L
A
F
----
E
I
N
P
E
E
L
K
K
A
F
E
G
F
K
A
L
K
V
K
G
I
N
V
T
V
P
F
K
E
E
I
I
P
L
L
D
Y
V
E
D
T
A
K
E
I
G
A
V
N
T
V
K
F
--
E
--
N
G
K
A
Y
G
Y
N
T
D
W
I
G
F
L
K
S
L
K
S
L
-
I
P
E
V
K
-
E
K
S
I
L
V
L
G
A
G
G
A
S
R
A
V
I
Y
--
A
L
V
K
E
G
A
K
-
V
F
L
W
N
R
------
T
K
E
K
A
I
K
---------
L
A
Q
K
F
P
L
E
V
V
N
S
P
E
E
V
I
D
K
V
Q
V
I
V
-------------
N
T
T
S
V
G
L
K
D
E
D
P
E
I
F
--
N
Y
D
L
I
K
K
D
H
V
V
V
D
I
I
Y
K
--
E
T
K
L
L
K
K
A
K
E
K
G
A
K
L
L
D
G
L
P
M
L
L
W
Q
G
I
E
A
F
K
I
W
N
G
C
E
V
P
---------
63
HHSearch
69.71
32%
-84
* C6 *
2D5C
4
AROE_THET8
A:
[1-257]
------------
M
L
R
F
-
A
V
L
G
H
P
V
A
H
S
L
S
P
A
M
H
A
F
A
L
E
S
L
G
L
E
G
S
Y
E
A
W
----
D
T
P
L
E
A
L
P
G
R
L
K
E
V
R
-
R
A
F
R
G
V
N
L
T
L
P
L
K
E
A
A
L
A
H
L
D
W
V
S
P
E
A
Q
R
I
G
A
V
N
T
V
L
Q
--
V
--
E
G
R
L
F
G
F
N
T
D
A
P
G
F
L
E
A
L
K
A
G
-
G
I
P
-
L
-
K
G
P
A
L
V
L
G
A
G
G
A
G
R
A
V
A
F
--
A
L
R
E
A
G
L
-
E
V
W
V
W
N
R
T
P
Q
---
R
A
L
A
L
A
E
E
F
G
-
L
R
A
---------
V
P
L
----
E
K
A
R
E
A
R
L
L
V
-------------
N
A
T
R
V
G
L
E
D
P
S
A
--
S
P
L
P
A
E
L
F
P
E
E
G
A
A
V
D
L
V
Y
R
P
L
W
T
R
F
L
R
E
A
K
A
K
G
L
K
V
Q
T
G
L
P
M
L
A
W
Q
G
A
L
A
F
R
L
W
T
G
L
L
P
D
P
S
G
M
E
E
A
A
-
35
PsiBlast_CBE
69.56
35%
-86
- C6 -
2HK9
2
AROE_AQUAE
B:
[8-262]
--------
I
N
A
Q
T
Q
L
Y
-
G
V
I
G
F
P
V
K
H
S
L
S
P
V
F
Q
N
A
L
I
R
Y
A
G
L
N
A
V
Y
L
A
F
----
E
I
N
P
E
E
L
K
K
A
F
E
G
F
K
A
L
K
V
K
G
I
N
V
T
V
P
F
K
E
E
I
I
P
L
L
D
Y
V
E
D
T
A
K
E
I
G
A
V
N
T
V
K
F
--
E
--
N
G
K
A
Y
G
Y
N
T
D
W
I
G
F
L
K
S
L
K
S
L
-
I
P
E
V
K
-
E
K
S
I
L
V
L
G
A
G
G
A
S
R
A
V
I
Y
--
A
L
V
K
E
G
A
K
-
V
F
L
W
N
R
------
T
K
E
K
A
I
K
---------
L
A
Q
K
F
P
L
E
V
V
N
S
P
E
E
V
I
D
K
V
Q
V
I
V
-------------
N
T
T
S
V
G
L
K
D
E
D
P
E
I
F
--
N
Y
D
L
I
K
K
D
H
V
V
V
D
I
I
Y
K
--
E
T
K
L
L
K
K
A
K
E
K
G
A
K
L
L
D
G
L
P
M
L
L
W
Q
G
I
E
A
F
K
I
W
N
G
C
E
V
P
---------
33
PsiBlast_CBE
69.54
35%
-86
- C6 -
2HK9
2
AROE_AQUAE
D:
[8-262]
--------
I
N
A
Q
T
Q
L
Y
-
G
V
I
G
F
P
V
K
H
S
L
S
P
V
F
Q
N
A
L
I
R
Y
A
G
L
N
A
V
Y
L
A
F
----
E
I
N
P
E
E
L
K
K
A
F
E
G
F
K
A
L
K
V
K
G
I
N
V
T
V
P
F
K
E
E
I
I
P
L
L
D
Y
V
E
D
T
A
K
E
I
G
A
V
N
T
V
K
F
--
E
--
N
G
K
A
Y
G
Y
N
T
D
W
I
G
F
L
K
S
L
K
S
L
-
I
P
E
V
K
-
E
K
S
I
L
V
L
G
A
G
G
A
S
R
A
V
I
Y
--
A
L
V
K
E
G
A
K
-
V
F
L
W
N
R
------
T
K
E
K
A
I
K
---------
L
A
Q
K
F
P
L
E
V
V
N
S
P
E
E
V
I
D
K
V
Q
V
I
V
-------------
N
T
T
S
V
G
L
K
D
E
D
P
E
I
F
--
N
Y
D
L
I
K
K
D
H
V
V
V
D
I
I
Y
K
--
E
T
K
L
L
K
K
A
K
E
K
G
A
K
L
L
D
G
L
P
M
L
L
W
Q
G
I
E
A
F
K
I
W
N
G
C
E
V
P
---------
34
PsiBlast_CBE
69.30
35%
-84
- C6 -
2HK9
2
AROE_AQUAE
C:
[8-262]
--------
I
N
A
Q
T
Q
L
Y
-
G
V
I
G
F
P
V
K
H
S
L
S
P
V
F
Q
N
A
L
I
R
Y
A
G
L
N
A
V
Y
L
A
F
----
E
I
N
P
E
E
L
K
K
A
F
E
G
F
K
A
L
K
V
K
G
I
N
V
T
V
P
F
K
E
E
I
I
P
L
L
D
Y
V
E
D
T
A
K
E
I
G
A
V
N
T
V
K
F
--
E
--
N
G
K
A
Y
G
Y
N
T
D
W
I
G
F
L
K
S
L
K
S
L
-
I
P
E
V
K
-
E
K
S
I
L
V
L
G
A
G
G
A
S
R
A
V
I
Y
--
A
L
V
K
E
G
A
K
-
V
F
L
W
N
R
------
T
K
E
K
A
I
K
---------
L
A
Q
K
F
P
L
E
V
V
N
S
P
E
E
V
I
D
K
V
Q
V
I
V
-------------
N
T
T
S
V
G
L
K
D
E
D
P
E
I
F
--
N
Y
D
L
I
K
K
D
H
V
V
V
D
I
I
Y
K
--
E
T
K
L
L
K
K
A
K
E
K
G
A
K
L
L
D
G
L
P
M
L
L
W
Q
G
I
E
A
F
K
I
W
N
G
C
E
V
P
---------
7
PsiBlast_PDB
68.57
39%
-82
- C6 -
1NVT
2
AROE_METJA
A:
[7-278]
--------
I
N
A
K
T
K
V
I
-
G
L
I
G
H
P
V
E
H
S
F
S
P
I
M
H
N
A
A
F
K
D
K
G
L
N
Y
V
Y
V
A
F
----
D
V
L
P
E
N
L
K
Y
V
I
D
G
A
K
A
L
G
I
V
G
F
N
V
T
I
P
H
K
I
E
I
M
K
Y
L
D
E
I
D
K
D
A
Q
L
I
G
A
V
N
T
I
K
I
--
E
--
D
G
K
A
I
G
Y
N
T
D
G
I
G
A
R
M
A
L
E
E
E
-
I
G
R
V
K
-
D
K
N
I
V
I
Y
G
A
G
G
A
A
R
A
V
A
F
--
E
L
A
------------
K
D
N
N
I
I
I
A
N
R
T
V
E
---------
K
A
E
A
L
A
K
E
I
A
E
K
L
N
K
K
F
G
E
E
V
K
F
S
G
LDVDLDGVD
I
I
I
N
A
T
P
I
G
M
Y
P
N
I
D
V
E
P
I
V
K
A
E
K
L
R
E
D
M
V
V
M
D
L
I
Y
N
P
L
E
T
V
L
L
K
E
A
K
K
V
N
A
K
T
I
N
G
L
G
M
L
I
Y
Q
G
A
V
A
F
K
I
W
T
G
V
E
P
N
I
E
V
M
K
----
32
PsiBlast_CBE
67.29
39%
-79
- C6 -
1NVT
2
AROE_METJA
B:
[7-278]
--------
I
N
A
K
T
K
V
I
-
G
L
I
G
H
P
V
E
H
S
F
S
P
I
M
H
N
A
A
F
K
D
K
G
L
N
Y
V
Y
V
A
F
----
D
V
L
P
E
N
L
K
Y
V
I
D
G
A
K
A
L
G
I
V
G
F
N
V
T
I
P
H
K
I
E
I
M
K
Y
L
D
E
I
D
K
D
A
Q
L
I
G
A
V
N
T
I
K
I
--
E
--
D
G
K
A
I
G
Y
N
T
D
G
I
G
A
R
M
A
L
E
E
E
-
I
G
R
V
K
-
D
K
N
I
V
I
Y
G
A
G
G
A
A
R
A
V
A
F
--
E
L
A
------------
K
D
N
N
I
I
I
A
N
R
T
V
E
---------
K
A
E
A
L
A
K
E
I
A
E
K
L
N
K
K
F
G
E
E
V
K
F
S
GLDVDLDGVDIII
N
A
T
P
I
G
M
Y
P
N
I
D
V
E
P
I
V
K
A
E
K
L
R
E
D
M
V
V
M
D
L
I
Y
N
P
L
E
T
V
L
L
K
E
A
K
K
V
N
A
K
T
I
N
G
L
G
M
L
I
Y
Q
G
A
V
A
F
K
I
W
T
G
V
E
P
N
I
E
V
M
K
----
18
PsiBlast_PDB
64.74
31%
-88
- C6 -
2D5C
4
AROE_THET8
A:
[4-244]
---------------
F
-
A
V
L
G
H
P
V
A
H
S
L
S
P
A
M
H
A
F
A
L
E
S
L
G
L
E
G
S
Y
E
A
W
D
T
P
L
E
A
L
P
G
R
L
K
E
V
R
R
A
F
R
G
V
N
L
-----
T
L
P
L
K
E
A
A
L
A
H
L
D
W
V
S
P
E
A
Q
R
I
G
A
V
N
T
V
L
Q
--
V
--
E
G
R
L
F
G
F
N
T
D
A
P
G
F
L
E
A
L
K
A
G
-
G
I
P
L
K
-
G
P
A
L
V
L
G
A
G
G
A
G
R
A
V
A
F
A
L
R
E
A
G
L
----
E
V
W
V
W
N
R
T
P
Q
---
R
A
L
A
L
A
E
E
F
G
-
L
R
A
------
V
P
L
E
K
A
R
E
A
R
-------
L
L
V
-------------
N
A
T
R
V
G
L
E
D
P
S
A
S
P
L
--
P
A
E
L
F
P
E
E
G
A
A
V
D
L
V
Y
R
P
L
W
T
R
F
L
R
E
A
K
A
K
G
L
K
V
Q
T
G
L
P
M
L
A
W
Q
G
A
L
A
F
R
L
W
T
--------------
41
PsiBlast_CBE
64.65
31%
-91
- C6 -
2D5C
3
AROE_THET8
B:
[4-244]
---------------
F
-
A
V
L
G
H
P
V
A
H
S
L
S
P
A
M
H
A
F
A
L
E
S
L
G
L
E
G
S
Y
E
A
W
D
T
P
L
E
A
L
P
G
R
L
K
E
V
R
R
A
F
R
G
V
N
L
-----
T
L
P
L
K
E
A
A
L
A
H
L
D
W
V
S
P
E
A
Q
R
I
G
A
V
N
T
V
L
Q
--
V
--
E
G
R
L
F
G
F
N
T
D
A
P
G
F
L
E
A
L
K
A
G
-
G
I
P
L
K
-
G
P
A
L
V
L
G
A
G
G
A
G
R
A
V
A
F
A
L
R
E
A
G
L
----
E
V
W
V
W
N
R
T
P
Q
---
R
A
L
A
L
A
E
E
F
G
-
L
R
A
------
V
P
L
E
K
A
R
E
A
R
-------
L
L
V
-------------
N
A
T
R
V
G
L
----
A
S
P
L
--
P
A
E
L
F
P
E
E
G
A
A
V
D
L
V
Y
R
P
L
W
T
R
F
L
R
E
A
K
A
K
G
L
K
V
Q
T
G
L
P
M
L
A
W
Q
G
A
L
A
F
R
L
W
T
--------------
40
PsiBlast_CBE
64.08
31%
-87
- C6 -
2EV9
2
AROE_THET8
B:
[4-244]
---------------
F
-
A
V
L
G
H
P
V
A
H
S
L
S
P
A
M
H
A
F
A
L
E
S
L
G
L
E
G
S
Y
E
A
W
DTPL
E
A
L
P
G
R
L
K
E
V
R
R
A
F
R
G
V
N
L
-----
T
L
P
L
K
E
A
A
L
A
H
L
D
W
V
S
P
E
A
Q
R
I
G
A
V
N
T
V
L
Q
--
V
--
E
G
R
L
F
G
F
N
T
D
A
P
G
F
L
E
A
L
K
A
G
-
G
I
P
L
K
-
G
P
A
L
V
L
G
A
G
G
A
G
R
A
V
A
F
A
LR
E
A
G
L
----
E
V
W
V
W
N
R
T
P
Q
---
R
A
L
A
L
A
E
E
F
G
-
L
R
A
------
V
P
L
E
K
A
R
E
A
R
-------
L
L
V
-------------
N
A
T
R
V
G
L
E
D
P
S
A
S
P
L
--
P
A
E
L
F
P
E
E
G
A
A
V
D
L
V
Y
R
P
L
W
T
R
F
L
R
E
A
K
A
K
G
L
K
V
Q
T
G
L
P
M
L
A
W
Q
G
A
L
A
F
R
L
W
T
--------------
19
PsiBlast_PDB
64.00
31%
-87
- C6 -
2EV9
3
AROE_THET8
A:
[4-244]
---------------
F
-
A
V
L
G
H
P
V
A
H
S
L
S
P
A
M
H
A
F
A
L
E
S
L
G
L
E
G
S
Y
E
A
W
D
T
P
L
E
A
L
P
G
R
L
K
E
V
R
R
A
F
R
G
V
N
L
-----
T
L
P
L
K
E
A
A
L
A
H
L
D
W
V
S
P
E
A
Q
R
I
G
A
V
N
T
V
L
Q
--
V
--
E
G
R
L
F
G
F
N
T
D
A
P
G
F
L
E
A
L
K
A
G
-
G
I
P
L
K
-
G
P
A
L
V
L
G
A
G
G
A
G
R
A
V
A
F
A
L
R
E
A
G
L
----
E
V
W
V
W
N
R
T
P
Q
---
R
A
L
A
L
A
E
E
F
G
-
L
R
A
------
V
P
L
E
K
A
R
E
A
R
-------
L
L
V
-------------
N
A
T
R
V
G
L
E
D
P
S
A
S
P
L
--
P
A
E
L
F
P
E
E
G
A
A
V
D
L
V
Y
R
P
L
W
T
R
F
L
R
E
A
K
A
K
G
L
K
V
Q
T
G
L
P
M
L
A
W
Q
G
A
L
A
F
R
L
W
T
--------------