@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0509: (2016-03-16 )
MAGKMKLFSVTSERPLATKIADYLDIPLCEVELQKFSDGEVKINIEESIRGTNAYVVQSMNSNVNERLMELLIMVDALKRASVHSINIIMPYYGYARQDRKARSREPITAKLMANLIQRAGANRLITVDLHAAQIQGFFNIPIDHLSAIPLIGDYLIENYGEKDVVVVAPDHSGVVRARRIADRLNAPIAILNRKPRPHEDEIMSVIGDVKGKVAIVVDDIIDTGVRATTSADILLEKGAVEVIACATHSVMAGNATERLQNSNIKEVITSDSIDLPEDKQFDKLTTISIGRILGRAIEGVQENRSLHPLF
Atome Classification :
(29 SA)
.........10........20........30........40........50........60........70........80........90........100.-.-.....----110.......120.......130.......140.......150........160.-...-....170.......180.......190.-.-.---....200.......210.......220.......230.......240.......250.-......260.......270....-...---280.......290.......300.......310
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MAG
K
M
K
L
F
S
VTSER
P
L
A
T
K
I
A
D
Y
LDIP
L
C
E
V
E
L
Q
KFSDG
E
V
K
I
N
I
EESIRGT
N
A
Y
V
V
QSMNS
N
V
N
E
R
L
M
E
L
L
I
M
V
D
A
L
K
RASV
H
S
I
N
I
IMPYYGYARQDRKAR-S-REP
I
T
----
A
K
L
M
A
N
L
I
Q
RAGAN
R
L
I
T
V
D
L
H
A
A
Q
I
Q
G
F
FNI
P
I
D
H
LSA
I
P
-
L
I
G
D
Y
L
I
E
NYG-E-K
D
V
-
V
V
V
APDHS
G
V
V
R
A
R
R
I
A
D
R
LNA
P
I
A
I
LN-R-K---PRP
H
E
D
E
I
M
S
V
I
G
DVKG
K
V
A
I
V
V
D
D
I
IDTGVRATTSA
D
I
L
LEKG
A
V
E
V
I
A
CATHSVMA-G
N
A
T
E
R
LQNS
N
I
K
E
V
ITSDSIDL-PED---KQFDKL
T
T
I
S
I
G
R
I
L
G
R
A
I
E
G
V
Q
ENRSLHPLF
1
PsiBlast_PDB
97.00
56%
-147
- C5 -
1DKU
3
KPRS_BACSU
A:
[10-316]
----
L
K
I
F
S
L
N
S
N
P
E
L
A
K
E
I
A
D
I
V
G
V
Q
L
G
K
C
S
V
T
R
F
S
D
G
E
V
Q
I
N
I
E
E
S
I
R
G
C
D
C
Y
I
I
Q
S
T
S
D
P
V
N
E
H
I
M
E
L
L
I
M
V
D
A
L
K
R
A
S
A
K
T
I
N
I
V
I
P
Y
Y
G
Y
A
R
Q
D
R
K
A
R
-
S
-
R
E
P
I
T
----
A
K
L
F
A
N
L
L
E
T
A
G
A
T
R
V
I
A
L
D
L
H
A
P
Q
I
Q
G
F
F
D
I
P
I
D
H
L
M
G
V
P
-
I
L
G
E
Y
F
-
E
G
K
N
-
L
-
E
D
I
-
V
I
V
S
P
D
H
G
G
V
T
R
A
R
K
L
A
D
R
L
K
A
P
I
A
I
I
D
K
R
-------------
M
N
I
V
G
N
I
E
G
K
T
A
I
L
I
D
D
I
I
D
T
A
G
T
I
T
L
A
A
N
A
L
V
E
N
G
A
K
E
V
Y
A
C
C
T
H
P
V
L
S
-
G
P
A
V
E
R
I
N
N
S
T
I
K
E
L
V
V
T
N
S
I
K
L
--------
K
I
E
R
F
K
Q
L
S
V
G
P
L
L
A
E
A
I
I
R
V
H
E
Q
Q
S
V
S
Y
L
F
22
PsiBlast_CBE
96.98
56%
-147
- C5 -
1DKR
3
KPRS_BACSU
B:
[10-316]
----
L
K
I
F
S
L
N
S
N
P
E
L
A
K
E
I
A
D
I
V
G
V
Q
L
G
K
C
S
V
T
R
F
S
D
G
E
V
Q
I
N
I
E
E
S
I
R
G
C
D
C
Y
I
I
Q
S
T
S
D
P
V
N
E
H
I
M
E
L
L
I
M
V
D
A
L
K
R
A
S
A
K
T
I
N
I
V
I
P
Y
Y
G
Y
A
R
Q
D
R
K
A
R
-
S
-
R
E
P
I
T
----
A
K
L
F
A
N
L
L
E
T
A
G
A
T
R
V
I
A
L
D
L
H
A
P
Q
I
Q
G
F
F
D
I
P
I
D
H
L
M
G
V
P
-
I
L
G
E
Y
F
-
E
G
K
N
-
L
-
E
D
I
-
V
I
V
S
P
D
H
G
G
V
T
R
A
R
K
L
A
D
R
L
K
A
P
I
A
I
I
D
K
R
-------------
M
N
I
V
G
N
I
E
G
K
T
A
I
L
I
D
D
I
I
D
T
A
G
T
I
T
L
A
A
N
A
L
V
E
N
G
A
K
E
V
Y
A
C
C
T
H
P
V
L
S
-
G
P
A
V
E
R
I
N
N
S
T
I
K
E
L
V
V
T
N
S
I
K
L
-
P
E
E
---
K
K
I
E
R
F
K
Q
L
S
V
G
P
L
L
A
E
A
I
I
R
V
H
E
Q
Q
S
V
S
Y
L
F
21
PsiBlast_CBE
96.81
56%
-148
- C5 -
1DKU
3
KPRS_BACSU
B:
[10-316]
----
L
K
I
F
S
L
N
S
N
P
E
L
A
K
E
I
A
D
I
V
G
V
Q
L
G
K
C
S
V
T
R
F
S
D
G
E
V
Q
I
N
I
E
E
S
I
R
G
C
D
C
Y
I
I
Q
S
T
S
D
P
V
N
E
H
I
M
E
L
L
I
M
V
D
A
L
K
R
A
S
A
K
T
I
N
I
V
I
P
Y
Y
G
Y
A
R
Q
D
R
K
A
R
-
S
-
R
E
P
I
T
----
A
K
L
F
A
N
L
L
E
T
A
G
A
T
R
V
I
A
L
D
L
H
A
P
Q
I
Q
G
F
F
D
I
P
I
D
H
L
M
G
V
P
-
I
L
G
E
Y
F
-
E
G
K
N
-
L
-
E
D
I
-
V
I
V
S
P
D
H
G
G
V
T
R
A
R
K
L
A
D
R
L
K
A
P
I
A
I
I
D
K
R
-------------
M
N
I
V
G
N
I
E
G
K
T
A
I
L
I
D
D
I
I
D
T
A
G
T
I
T
L
A
A
N
A
L
V
E
N
G
A
K
E
V
Y
A
C
C
T
H
P
V
L
S
-
G
P
A
V
E
R
I
N
N
S
T
I
K
E
L
V
V
T
N
S
I
K
L
--------
K
I
E
R
F
K
Q
L
S
V
G
P
L
L
A
E
A
I
I
R
V
H
E
Q
Q
S
V
S
Y
L
F
47
Fugue
96.30
55%
-140
- C5 -
1DKU
3
KPRS_BACSU
A:
[9-316]
---
N
L
K
I
F
S
L
N
S
N
P
E
L
A
K
E
I
A
D
I
V
G
V
Q
L
G
K
C
S
V
T
R
F
S
D
G
E
V
Q
I
N
I
E
E
S
I
R
G
C
D
C
Y
I
I
Q
S
T
S
D
P
V
N
E
H
I
M
E
L
L
I
M
V
D
A
L
K
R
A
S
A
K
T
I
N
I
V
I
P
Y
Y
G
Y
A
R
Q
D
R
K
A
R
-
S
-
R
E
P
I
T
----
A
K
L
F
A
N
L
L
E
T
A
G
A
T
R
V
I
A
L
D
L
H
A
P
Q
I
Q
G
F
F
D
I
P
I
D
H
L
M
G
V
P
-
I
L
G
E
Y
F
E
G
K
-
N
-
L
-
E
D
I
-
V
I
V
S
P
D
H
G
G
V
T
R
A
R
K
L
A
D
R
L
K
A
P
I
A
I
I
D
-
K
-
R
-----------
M
N
I
V
G
N
I
E
G
K
T
A
I
L
I
D
D
I
I
D
T
A
G
T
I
T
L
A
A
N
A
L
V
E
N
G
A
K
E
V
Y
A
C
C
T
H
P
V
L
S
-
G
P
A
V
E
R
I
N
N
S
T
I
K
E
L
V
V
T
N
S
I
K
--------
L
K
I
E
R
F
K
Q
L
S
V
G
P
L
L
A
E
A
I
I
R
V
H
E
Q
Q
S
V
S
Y
L
F
60
HHSearch
95.99
56%
-143
- C5 -
1DKU
3
KPRS_BACSU
A:
[9-316]
---
N
L
K
I
F
S
L
N
S
N
P
E
L
A
K
E
I
A
D
I
V
G
V
Q
L
G
K
C
S
V
T
R
F
S
D
G
E
V
Q
I
N
I
E
E
S
I
R
G
C
D
C
Y
I
I
Q
S
T
S
D
P
V
N
E
H
I
M
E
L
L
I
M
V
D
A
L
K
R
A
S
A
K
T
I
N
I
V
I
P
Y
Y
G
Y
A
R
Q
D
R
K
A
R
-
S
-
R
E
P
I
T
----
A
K
L
F
A
N
L
L
E
T
A
G
A
T
R
V
I
A
L
D
L
H
A
P
Q
I
Q
G
F
F
D
I
P
I
D
H
L
M
G
V
P
-
I
L
G
E
Y
F
E
G
K
N
--
L
-
E
D
I
-
V
I
V
S
P
D
H
G
G
V
T
R
A
R
K
L
A
D
R
L
K
A
P
I
A
I
I
D
K
R
-------------
M
N
I
V
G
N
I
E
G
K
T
A
I
L
I
D
D
I
I
D
T
A
G
T
I
T
L
A
A
N
A
L
V
E
N
G
A
K
E
V
Y
A
C
C
T
H
P
V
L
S
-
G
P
A
V
E
R
I
N
N
S
T
I
K
E
L
V
V
T
N
S
I
K
L
--------
K
I
E
R
F
K
Q
L
S
V
G
P
L
L
A
E
A
I
I
R
V
H
E
Q
Q
S
V
S
Y
L
F
10
PsiBlast_PDB
93.27
41%
-139
- C5 -
3S5J
3
PRPS1_HUMAN
B:
[4-313]
----
I
K
I
F
S
G
S
S
H
Q
D
L
S
Q
K
I
A
D
R
L
G
L
E
L
G
K
V
V
T
K
K
F
S
N
Q
E
T
C
V
E
I
G
E
S
V
R
G
E
D
V
Y
I
V
Q
S
G
C
G
E
I
N
D
N
L
M
E
L
L
I
M
I
N
A
C
K
I
A
S
A
S
R
V
T
A
V
I
P
C
F
P
Y
A
R
Q
D
K
K
D
K
-
S
-
R
A
P
I
S
----
A
K
L
V
A
N
M
L
S
V
A
G
A
D
H
I
I
T
M
D
L
H
A
S
Q
I
Q
G
F
F
D
I
P
V
D
N
L
Y
A
E
P
-
A
V
L
K
W
I
R
E
N
I
S
-
E
W
R
N
C
-
T
I
V
S
P
D
A
G
G
A
K
R
V
T
S
I
A
D
R
L
N
V
D
F
A
L
I
H
-
K
E----------
D
R
M
V
L
V
G
D
V
K
D
R
V
A
I
L
V
D
D
M
A
D
T
C
G
T
I
C
H
A
A
D
K
L
L
S
A
G
A
T
R
V
Y
A
I
L
T
H
G
I
F
S
-
G
P
A
I
S
R
I
N
N
A
C
F
E
A
V
V
V
T
N
T
I
---
P
Q
E
DKM
K
H
C
S
K
I
Q
V
I
D
I
S
M
I
L
A
E
A
I
R
R
T
H
N
G
E
S
V
S
Y
L
F
58
HHSearch
93.18
42%
-136
* C5 *
3S5J
3
PRPS1_HUMAN
B:
[3-313]
---
N
I
K
I
F
S
G
S
S
H
Q
D
L
S
Q
K
I
A
D
R
L
G
L
E
L
G
K
V
V
T
K
K
F
S
N
Q
E
T
C
V
E
I
G
E
S
V
R
G
E
D
V
Y
I
V
Q
S
G
C
G
E
I
N
D
N
L
M
E
L
L
I
M
I
N
A
C
K
I
A
S
A
S
R
V
T
A
V
I
P
C
F
P
Y
A
R
Q
D
K
K
D
K
-
S
-
R
A
P
I
S
----
A
K
L
V
A
N
M
L
S
V
A
G
A
D
H
I
I
T
M
D
L
H
A
S
Q
I
Q
G
F
F
D
I
P
V
D
N
L
Y
A
E
P
-
A
V
L
K
W
I
R
E
N
I
S
E
W
-
R
N
C
-
T
I
V
S
P
D
A
G
G
A
K
R
V
T
S
I
A
D
R
L
N
V
D
F
A
L
I
H
K
E
-----------
D
R
M
V
L
V
G
D
V
K
D
R
V
A
I
L
V
D
D
M
A
D
T
C
G
T
I
C
H
A
A
D
K
L
L
S
A
G
A
T
R
V
Y
A
I
L
T
H
G
I
F
S
-
G
P
A
I
S
R
I
N
N
A
C
F
E
A
V
V
V
T
N
T
I
P
Q
-
E
D
K
M--
K
H
C
S
K
I
Q
V
I
D
I
S
M
I
L
A
E
A
I
R
R
T
H
N
G
E
S
V
S
Y
L
F
5
PsiBlast_PDB
93.06
41%
-139
- C5 -
4LYG
2
PRPS1_HUMAN
A:
[4-313]
----
I
K
I
F
S
G
S
S
H
Q
D
L
S
Q
K
I
A
D
R
L
G
L
E
L
G
K
V
V
T
K
K
F
S
N
Q
E
T
C
V
T
I
G
E
S
V
R
G
E
D
V
Y
I
V
Q
S
G
C
G
E
I
N
D
N
L
M
E
L
L
I
M
I
N
A
C
K
I
A
S
A
S
R
V
T
A
V
I
P
C
F
P
Y
A
R
Q
D
K
K
D
K
-
S
-
R
A
P
I
S
----
A
K
L
V
A
N
M
L
S
V
A
G
A
D
H
I
I
T
M
D
L
H
A
S
Q
I
Q
G
F
F
D
I
P
V
D
N
L
Y
A
E
P
-
A
V
L
K
W
I
R
E
N
I
S
-
E
W
R
N
C
-
T
I
V
S
P
D
A
G
G
A
K
R
V
T
S
I
A
D
R
L
N
V
D
F
A
L
I
H
-
K
E----------
D
R
M
V
L
V
G
D
V
K
D
R
V
A
I
L
V
D
D
M
A
D
T
C
G
T
I
C
H
A
A
D
K
L
L
S
A
G
A
T
R
V
Y
A
I
L
T
H
G
I
F
S
-
G
P
A
I
S
R
I
N
N
A
C
F
E
A
V
V
V
T
N
T
I
---
P
Q
E
D
K
M
K
H
C
S
K
I
Q
V
I
D
I
S
M
I
L
A
E
A
I
R
R
T
H
N
G
E
S
V
S
Y
L
F
27
PsiBlast_CBE
93.02
41%
-141
- C5 -
4LYG
3
PRPS1_HUMAN
B:
[4-313]
----
I
K
I
F
S
G
S
S
H
Q
D
L
S
Q
K
I
A
D
R
L
G
L
E
L
G
K
V
V
T
K
K
F
S
N
Q
E
T
C
V
T
I
G
E
S
V
R
G
E
D
V
Y
I
V
Q
S
G
C
G
E
I
N
D
N
L
M
E
L
L
I
M
I
N
A
C
K
I
A
S
A
S
R
V
T
A
V
I
P
C
F
P
Y
A
R
Q
D
K
K
D
K
-
S
-
R
A
P
I
S
----
A
K
L
V
A
N
M
L
S
V
A
G
A
D
H
I
I
T
M
D
L
H
A
S
Q
I
Q
G
F
F
D
I
P
V
D
N
L
Y
A
E
P
-
A
V
L
K
W
I
R
E
N
I
S
-
E
W
R
N
C
-
T
I
V
S
P
D
A
G
G
A
K
R
V
T
S
I
A
D
R
L
N
V
D
F
A
L
I
H
-
K
E
R
---
K
-----
D
R
M
V
L
V
G
D
V
K
D
R
V
A
I
L
V
D
D
M
A
D
T
C
G
T
I
C
H
A
A
D
K
L
L
S
A
G
A
T
R
V
Y
A
I
L
T
H
G
I
F
S
-
G
P
A
I
S
R
I
N
N
A
C
F
E
A
V
V
V
T
N
T
I
---
P
Q
E
D
K
M
K
H
C
S
K
I
Q
V
I
D
I
S
M
I
L
A
E
A
I
R
R
T
H
N
G
E
S
V
S
Y
L
F
35
PsiBlast_CBE
92.90
41%
-141
- C5 -
4M0P
3
PRPS1_HUMAN
B:
[4-313]
----
I
K
I
F
S
G
S
S
H
Q
D
L
S
Q
K
I
A
D
R
L
G
L
E
L
G
K
V
V
T
K
K
F
S
N
Q
E
T
C
V
E
I
G
E
S
V
R
G
E
D
V
Y
I
V
Q
S
G
C
G
E
I
N
D
N
L
M
E
L
L
I
M
I
N
A
C
K
I
A
S
A
S
R
V
T
A
V
I
P
C
F
P
Y
A
R
Q
D
K
K
D
K
-
S
-
R
A
P
I
S
----
A
K
L
V
A
N
T
L
S
V
A
G
A
D
H
I
I
T
M
D
L
H
A
S
Q
I
Q
G
F
F
D
I
P
V
D
N
L
Y
A
E
P
-
A
V
L
K
W
I
R
E
N
I
S
-
E
W
R
N
C
-
T
I
V
S
P
D
A
G
G
A
K
R
V
T
S
I
A
D
R
L
N
V
D
F
A
L
I
H
-
K
E----------
D
R
M
V
L
V
G
D
V
K
D
R
V
A
I
L
V
D
D
M
A
D
T
C
G
T
I
C
H
A
A
D
K
L
L
S
A
G
A
T
R
V
Y
A
I
L
T
H
G
I
F
S
-
G
P
A
I
S
R
I
N
N
A
C
F
E
A
V
V
V
T
N
T
I
---
P
Q
E
DKM
K
H
C
S
K
I
Q
V
I
D
I
S
M
I
L
A
E
A
I
R
R
T
H
N
G
E
S
V
S
Y
L
F
26
PsiBlast_CBE
92.62
41%
-139
- C5 -
4LZO
3
PRPS1_HUMAN
B:
[4-313]
----
I
K
I
F
S
G
S
S
H
Q
D
L
S
Q
K
I
A
D
R
L
G
L
E
L
G
K
V
V
T
K
K
F
S
N
Q
E
T
C
V
E
I
G
E
S
V
R
G
E
D
V
Y
I
V
Q
S
G
C
G
E
I
N
D
N
L
M
E
L
L
I
M
I
N
A
C
K
I
A
S
A
S
R
V
T
T
V
I
P
C
F
P
Y
A
R
Q
D
K
K
D
K
-
S
-
R
A
P
I
S
----
A
K
L
V
A
N
M
L
S
V
A
G
A
D
H
I
I
T
M
D
L
H
A
S
Q
I
Q
G
F
F
D
I
P
V
D
N
L
Y
A
E
P
-
A
V
L
K
W
I
R
E
N
I
S
-
E
W
R
N
C
-
T
I
V
S
P
D
A
G
G
A
K
R
V
T
S
I
A
D
R
L
N
V
D
F
A
L
I
H
-
K
E----------
D
R
M
V
L
V
G
D
V
K
D
R
V
A
I
L
V
D
D
M
A
D
T
C
G
T
I
C
H
A
A
D
K
L
L
S
A
G
A
T
R
V
Y
A
I
L
T
H
G
I
F
S
-
G
P
A
I
S
R
I
N
N
A
C
F
E
A
V
V
V
T
N
T
I
---
P
Q
E
DKM
K
H
C
S
K
I
Q
V
I
D
I
S
M
I
L
A
E
A
I
R
R
T
H
N
G
E
S
V
S
Y
L
F
31
PsiBlast_CBE
92.60
41%
-138
- C5 -
2HCR
8
PRPS1_HUMAN
B:
[4-313]
----
I
K
I
F
S
G
S
S
H
Q
D
L
S
Q
K
I
A
D
R
L
G
L
E
L
G
K
V
V
T
K
K
F
S
N
Q
E
T
C
V
E
I
G
E
S
V
R
G
E
D
V
Y
I
V
Q
S
G
C
G
E
I
N
D
N
L
M
E
L
L
I
M
I
N
A
C
K
I
A
S
A
S
R
V
T
A
V
I
P
C
F
P
Y
A
R
Q
D
K
K
D
K
-
S
-
R
A
P
I
S
----
A
K
L
V
A
N
M
L
S
V
A
G
A
D
H
I
I
T
M
D
L
H
A
S
Q
I
Q
G
F
F
D
I
P
V
D
N
L
Y
A
E
P
-
A
V
L
K
W
I
R
E
N
I
S
-
E
W
R
N
C
-
T
I
V
S
P
D
A
G
G
A
K
R
V
T
S
I
A
D
R
L
N
V
D
F
A
L
I
H
-
K
E----------
D
R
M
V
L
V
G
D
V
K
D
R
V
A
I
L
V
D
D
M
A
D
T
C
G
T
I
C
H
A
A
D
K
L
L
S
A
G
A
T
R
V
Y
A
I
L
T
H
G
I
F
S
-
G
P
A
I
S
R
I
N
N
A
C
F
E
A
V
V
V
T
N
T
I
---
P
Q
E
D
K
M
K
H
C
S
K
I
Q
V
I
D
I
S
M
I
L
A
E
A
I
R
R
T
H
N
G
E
S
V
S
Y
L
F
28
PsiBlast_CBE
92.43
41%
-137
- C5 -
2H08
5
PRPS1_HUMAN
B:
[4-313]
----
I
K
I
F
S
G
S
S
H
Q
D
L
S
Q
K
I
A
D
R
L
G
L
E
L
G
K
V
V
T
K
K
F
S
N
Q
E
T
C
V
E
I
G
E
S
V
R
G
E
D
V
Y
I
V
Q
S
G
C
G
E
I
N
D
N
L
M
E
L
L
I
M
I
N
A
C
K
I
A
S
A
S
R
V
T
A
V
I
P
C
F
P
Y
A
R
Q
D
K
K
D
K
-
S
-
R
A
P
I
S
----
A
K
L
V
A
N
M
L
S
V
A
G
A
D
H
I
I
T
M
D
L
H
A
S
Q
I
Q
G
F
F
D
I
P
V
D
N
L
M
A
E
P
-
A
V
L
K
W
I
R
E
N
I
S
-
E
W
R
N
C
-
T
I
V
S
P
D
A
G
G
A
K
R
V
T
S
I
A
D
R
L
N
V
D
F
A
L
I
H
-
K
E----------
D
R
M
V
L
V
G
D
V
K
D
R
V
A
I
L
V
D
D
M
A
D
T
C
G
T
I
C
H
A
A
D
K
L
L
S
A
G
A
T
R
V
Y
A
I
L
T
H
G
I
F
S
-
G
P
A
I
S
R
I
N
N
A
C
F
E
A
V
V
V
T
N
T
I
---
P
Q
E
D
K
M
K
H
C
S
K
I
Q
V
I
D
I
S
M
I
L
A
E
A
I
R
R
T
H
N
G
E
S
V
S
Y
L
F
13
PsiBlast_PDB
92.38
41%
-136
- C5 -
4M0P
3
PRPS1_HUMAN
A:
[4-313]
----
I
K
I
F
S
G
S
S
H
Q
D
L
S
Q
K
I
A
D
R
L
G
L
E
L
G
K
V
V
T
K
K
F
S
N
Q
E
T
C
V
E
I
G
E
S
V
R
G
E
D
V
Y
I
V
Q
S
G
C
G
E
I
N
D
N
L
M
E
L
L
I
M
I
N
A
C
K
I
A
S
A
S
R
V
T
A
V
I
P
C
F
P
Y
A
R
Q
D
K
K
D
K
-
S
-
R
A
P
I
S
----
A
K
L
V
A
N
T
L
S
V
A
G
A
D
H
I
I
T
M
D
L
H
A
S
Q
I
Q
G
F
F
D
I
P
V
D
N
L
Y
A
E
P
-
A
V
L
K
W
I
R
E
N
I
S
-
E
W
R
N
C
-
T
I
V
S
P
D
A
G
G
A
K
R
V
T
S
I
A
D
R
L
N
V
D
F
A
L
I
H
-
K
E----------
D
R
M
V
L
V
G
D
V
K
D
R
V
A
I
L
V
D
D
M
A
D
T
C
G
T
I
C
H
A
A
D
K
L
L
S
A
G
A
T
R
V
Y
A
I
L
T
H
G
I
F
S
-
G
P
A
I
S
R
I
N
N
A
C
F
E
A
V
V
V
T
N
T
I
---
P
Q
E
D
K
M
K
H
C
S
K
I
Q
V
I
D
I
S
M
I
L
A
E
A
I
R
R
T
H
N
G
E
S
V
S
Y
L
F
9
PsiBlast_PDB
92.36
41%
-140
- C5 -
3EFH
4
PRPS1_HUMAN
A:
[4-313]
----
I
K
I
F
S
G
S
S
H
Q
D
L
S
Q
K
I
A
D
R
L
G
L
E
L
G
K
V
V
T
K
K
F
S
N
Q
E
T
C
V
E
I
G
E
S
V
R
G
E
D
V
Y
I
V
Q
S
G
C
G
E
I
N
D
N
L
M
E
L
L
I
M
I
N
A
C
K
I
A
S
A
S
R
V
T
A
V
I
P
C
F
P
Y
A
R
Q
D
K
K
D
K
-
S
-
R
A
P
I
S
----
A
K
L
V
A
N
M
L
S
V
A
G
A
D
H
I
I
T
M
D
L
H
A
S
Q
I
Q
G
F
F
D
I
P
V
D
N
L
Y
A
E
P
-
A
V
L
K
W
I
R
E
N
I
S
-
E
W
R
N
C
-
T
I
V
S
P
D
A
G
G
A
K
R
V
T
S
I
A
D
R
L
N
V
D
F
A
L
I
H
-
K
E
R
---
K
-------
M
V
L
V
G
D
V
K
D
R
V
A
I
L
V
D
D
M
A
D
T
C
G
T
I
C
H
A
A
D
K
L
L
S
A
G
A
T
R
V
Y
A
I
L
T
H
G
I
F
S
-
G
P
A
I
S
R
I
N
N
A
C
F
E
A
V
V
V
T
N
T
I
---
P
Q
E
D
K
M
K
H
C
S
K
I
Q
V
I
D
I
S
M
I
L
A
E
A
I
R
R
T
H
N
G
E
S
V
S
Y
L
F
32
PsiBlast_CBE
92.35
41%
-134
- C5 -
2H06
5
PRPS1_HUMAN
B:
[4-313]
----
I
K
I
F
S
G
S
S
H
Q
D
L
S
Q
K
I
A
D
R
L
G
L
E
L
G
K
V
V
T
K
K
F
S
N
Q
E
T
C
V
E
I
G
E
S
V
R
G
E
D
V
Y
I
V
Q
S
G
C
G
E
I
N
D
N
L
M
E
L
L
I
M
I
N
A
C
K
I
A
S
A
S
R
V
T
A
V
I
P
C
F
P
Y
A
R
Q
D
K
K
D
K
-
S
-
R
A
P
I
S
----
A
K
L
V
A
N
M
L
S
V
A
G
A
D
H
I
I
T
M
D
L
H
A
S
Q
I
Q
G
F
F
D
I
P
V
D
N
L
Y
A
E
P
-
A
V
L
K
W
I
R
E
N
I
S
-
E
W
R
N
C
-
T
I
V
S
P
D
A
G
G
A
K
R
V
T
S
I
A
D
R
L
N
V
D
F
A
L
I
H
-
K
E----------
D
R
M
V
L
V
G
D
V
K
D
R
V
A
I
L
V
D
D
M
A
D
T
C
G
T
I
C
H
A
A
D
K
L
L
S
A
G
A
T
R
V
Y
A
I
L
T
H
G
I
F
S
-
G
P
A
I
S
R
I
N
N
A
C
F
E
A
V
V
V
T
N
T
I
---
P
Q
E
D
K
M
K
H
C
S
K
I
Q
V
I
D
I
S
M
I
L
A
E
A
I
R
R
T
H
N
G
E
S
V
S
Y
L
F
34
PsiBlast_CBE
92.32
41%
-137
- C5 -
4LZN
3
PRPS1_HUMAN
A:
[4-313]
----
I
K
I
F
S
G
S
S
H
Q
D
L
S
Q
K
I
A
D
R
L
G
L
E
L
G
K
V
V
T
K
K
F
S
N
Q
E
T
C
V
E
I
G
E
S
V
R
G
E
D
V
Y
I
V
Q
S
G
C
G
E
I
N
N
N
L
M
E
L
L
I
M
I
N
A
C
K
I
A
S
A
S
R
V
T
A
V
I
P
C
F
P
Y
A
R
Q
D
K
K
D
K
-
S
-
R
A
P
I
S
----
A
K
L
V
A
N
M
L
S
V
A
G
A
D
H
I
I
T
M
D
L
H
A
S
Q
I
Q
G
F
F
D
I
P
V
D
N
L
Y
A
E
P
-
A
V
L
K
W
I
R
E
N
I
S
-
E
W
R
N
C
-
T
I
V
S
P
D
A
G
G
A
K
R
V
T
S
I
A
D
R
L
N
V
D
F
A
L
I
H
-
K
E----------
D
R
M
V
L
V
G
D
V
K
D
R
V
A
I
L
V
D
D
M
A
D
T
C
G
T
I
C
H
A
A
D
K
L
L
S
A
G
A
T
R
V
Y
A
I
L
T
H
G
I
F
S
-
G
P
A
I
S
R
I
N
N
A
C
F
E
A
V
V
V
T
N
T
I
---
P
Q
E
D
K
M
K
H
C
S
K
I
Q
V
I
D
I
S
M
I
L
A
E
A
I
R
R
T
H
N
G
E
S
V
S
Y
L
F
12
PsiBlast_PDB
92.29
41%
-138
- C5 -
4LZN
3
PRPS1_HUMAN
B:
[4-313]
----
I
K
I
F
S
G
S
S
H
Q
D
L
S
Q
K
I
A
D
R
L
G
L
E
L
G
K
V
V
T
K
K
F
S
N
Q
E
T
C
V
E
I
G
E
S
V
R
G
E
D
V
Y
I
V
Q
S
G
C
G
E
I
N
N
N
L
M
E
L
L
I
M
I
N
A
C
K
I
A
S
A
S
R
V
T
A
V
I
P
C
F
P
Y
A
R
Q
D
K
K
D
K
-
S
-
R
A
P
I
S
----
A
K
L
V
A
N
M
L
S
V
A
G
A
D
H
I
I
T
M
D
L
H
A
S
Q
I
Q
G
F
F
D
I
P
V
D
N
L
Y
A
E
P
-
A
V
L
K
W
I
R
E
N
I
S
-
E
W
R
N
C
-
T
I
V
S
P
D
A
G
G
A
K
R
V
T
S
I
A
D
R
L
N
V
D
F
A
L
I
H
-
K
E----------
D
R
M
V
L
V
G
D
V
K
D
R
V
A
I
L
V
D
D
M
A
D
T
C
G
T
I
C
H
A
A
D
K
L
L
S
A
G
A
T
R
V
Y
A
I
L
T
H
G
I
F
S
-
G
P
A
I
S
R
I
N
N
A
C
F
E
A
V
V
V
T
N
T
I
---
P
Q
E
DKM
K
H
C
S
K
I
Q
V
I
D
I
S
M
I
L
A
E
A
I
R
R
T
H
N
G
E
S
V
S
Y
L
F
11
PsiBlast_PDB
92.24
41%
-138
- C5 -
4F8E
6
PRPS1_HUMAN
A:
[4-313]
----
I
K
I
F
S
G
S
S
H
Q
D
L
S
Q
K
I
A
D
R
L
G
L
E
L
G
K
V
V
T
K
K
F
S
N
Q
E
T
C
V
E
I
G
E
S
V
R
G
E
H
V
Y
I
V
Q
S
G
C
G
E
I
N
D
N
L
M
E
L
L
I
M
I
N
A
C
K
I
A
S
A
S
R
V
T
A
V
I
P
C
F
P
Y
A
R
Q
D
K
K
D
K
-
S
-
R
A
P
I
S
----
A
K
L
V
A
N
M
L
S
V
A
G
A
D
H
I
I
T
M
D
L
H
A
S
Q
I
Q
G
F
F
D
I
P
V
D
N
L
Y
A
E
P
-
A
V
L
K
W
I
R
E
N
I
S
-
E
W
R
N
C
-
T
I
V
S
P
D
A
G
G
A
K
R
V
T
S
I
A
D
R
L
N
V
D
F
A
L
I
H
-
K
E
R
----------
R
M
V
L
V
G
D
V
K
D
R
V
A
I
L
V
D
D
M
A
D
T
C
G
T
I
C
H
A
A
D
K
L
L
S
A
G
A
T
R
V
Y
A
I
L
T
H
G
I
F
S
-
G
P
A
I
S
R
I
N
N
A
C
F
E
A
V
V
V
T
N
T
I
---
P
Q
E
D
K
M
K
H
C
S
K
I
Q
V
I
D
I
S
M
I
L
A
E
A
I
R
R
T
H
N
G
E
S
V
S
Y
L
F
25
PsiBlast_CBE
92.16
42%
-138
- C5 -
2H07
5
PRPS1_HUMAN
B:
[4-313]
----
I
K
I
F
S
G
S
S
H
Q
D
L
S
Q
K
I
A
D
R
L
G
L
E
L
G
K
V
V
T
K
K
F
S
N
Q
E
T
C
V
E
I
G
E
S
V
R
G
E
D
V
Y
I
V
Q
S
G
C
G
E
I
N
D
N
L
M
E
L
L
I
M
I
N
A
C
K
I
A
S
A
S
R
V
T
A
V
I
P
C
F
P
Y
A
R
Q
D
K
K
D
K
-
S
-
R
A
P
I
S
----
A
K
L
V
A
N
M
L
S
V
A
G
A
D
H
I
I
T
M
D
L
H
A
A
Q
I
Q
G
F
F
D
I
P
V
D
N
L
Y
A
E
P
-
A
V
L
K
W
I
R
E
N
I
S
-
E
W
R
N
C
-
T
I
V
S
P
D
A
G
G
A
K
R
V
T
S
I
A
D
R
L
N
V
D
F
A
L
I
H
-
K
E----------
D
R
M
V
L
V
G
D
V
K
D
R
V
A
I
L
V
D
D
M
A
D
T
C
G
T
I
C
H
A
A
D
K
L
L
S
A
G
A
T
R
V
Y
A
I
L
T
H
G
I
F
S
-
G
P
A
I
S
R
I
N
N
A
C
F
E
A
V
V
V
T
N
T
I
---
P
Q
E
D
K
M
K
H
C
S
K
I
Q
V
I
D
I
S
M
I
L
A
E
A
I
R
R
T
H
N
G
E
S
V
S
Y
L
F
8
PsiBlast_PDB
91.87
41%
-139
- C5 -
2HCR
8
PRPS1_HUMAN
A:
[4-313]
----
I
K
I
F
S
G
S
S
H
Q
D
L
S
Q
K
I
A
D
R
L
G
L
E
L
G
K
V
V
T
K
K
F
S
N
Q
E
T
C
V
E
I
G
E
S
V
R
G
E
D
V
Y
I
V
Q
S
G
C
G
E
I
N
D
N
L
M
E
L
L
I
M
I
N
A
C
K
I
A
S
A
S
R
V
T
A
V
I
P
C
F
P
Y
A
R
Q
D
K
K
D
K
-
S
-
R
A
P
I
S
----
A
K
L
V
A
N
M
L
S
V
A
G
A
D
H
I
I
T
M
D
L
H
A
S
Q
I
Q
G
F
F
D
I
P
V
D
N
L
Y
A
E
P
-
A
V
L
K
W
I
R
E
N
I
S
-
E
W
R
N
C
-
T
I
V
S
P
D
A
G
G
A
K
R
V
T
S
I
A
D
R
L
N
V
D
F
A
L
I
H
-
K
E
R
---------
D
R
M
V
L
V
G
D
V
K
D
R
V
A
I
L
V
D
D
M
A
D
T
C
G
T
I
C
H
A
A
D
K
L
L
S
A
G
A
T
R
V
Y
A
I
L
T
H
G
I
F
S
-
G
P
A
I
S
R
I
N
N
A
C
F
E
A
V
V
V
T
N
T
I
---
P
Q
E
D
K
M
K
H
C
S
K
I
Q
V
I
D
I
S
M
I
L
A
E
A
I
R
R
T
H
N
G
E
S
V
S
Y
L
F
24
PsiBlast_CBE
89.50
42%
-135
- C5 -
3DAH
7
?
B:
[8-316]
----
L
M
V
F
T
G
N
A
N
P
A
L
A
Q
E
V
V
K
I
L
G
I
P
L
G
K
A
M
V
S
R
F
S
D
G
E
I
Q
V
E
I
Q
E
N
V
R
G
K
D
V
F
V
L
Q
S
T
C
A
P
T
N
D
N
L
M
E
L
M
I
M
V
D
A
L
K
R
A
S
A
G
R
I
T
A
A
I
P
Y
F
G
Y
A
R
Q
D
R
R
P
R
-
S
A
R
V
A
I
S
----
A
K
V
V
A
N
M
L
E
I
A
G
V
E
R
I
I
T
M
D
L
H
A
D
Q
I
Q
G
F
F
D
I
P
V
D
N
I
Y
A
T
P
I
L
L
G
D
L
R
K
Q
N
Y
----
P
D
L
-
L
V
V
S
P
D
V
G
G
V
V
R
A
R
A
L
A
K
Q
L
N
C
D
L
A
---------------------
I
G
E
V
E
G
R
T
C
V
I
M
D
D
M
V
D
T
A
G
T
L
C
K
A
A
Q
V
L
K
E
R
G
A
K
Q
V
F
A
Y
A
T
H
P
V
L
S
-
G
G
A
A
D
R
I
A
A
S
A
L
D
E
L
V
V
T
D
T
I
P
L
S
A
E
S
---
L
A
C
P
K
I
R
A
L
S
S
A
G
L
L
A
E
T
F
S
R
I
R
R
G
D
S
V
M
S
L
F
23
PsiBlast_CBE
88.83
42%
-136
- C5 -
3DAH
5
?
C:
[8-313]
----
L
M
V
F
T
G
N
A
N
P
A
L
A
Q
E
V
V
K
I
L
G
I
P
L
G
K
A
M
V
S
R
F
S
D
G
E
I
Q
V
E
I
Q
E
N
V
R
G
K
D
V
F
V
L
Q
S
T
C
A
P
T
N
D
N
L
M
E
L
M
I
M
V
D
A
L
K
R
A
S
A
G
R
I
T
A
A
I
P
Y
F
G
Y
A
R
Q
D
R
R
P
R
-
S
A
R
V
A
I
S
----
A
K
V
V
A
N
M
L
E
I
A
G
V
E
R
I
I
T
M
D
L
H
A
D
Q
I
Q
G
F
F
D
I
P
V
D
N
I
Y
A
T
P
I
L
L
G
D
L
R
K
Q
N
Y
----
P
D
L
-
L
V
V
S
P
D
V
G
G
V
V
R
A
R
A
L
A
K
Q
L
N
C
D
L
A
I
I
D
K
R
-
R
----------
V
M
N
I
I
G
E
V
E
G
R
T
C
V
I
M
D
D
M
V
D
T
A
G
T
L
C
K
A
A
Q
V
L
K
E
R
G
A
K
Q
V
F
A
Y
A
T
H
P
V
L
S
-
G
G
A
A
D
R
I
A
A
S
A
L
D
E
L
V
V
T
D
T
I
P
L
S
A
E
S
---
L
A
C
P
K
I
R
A
L
S
S
A
G
L
L
A
E
T
F
S
R
I
R
R
G
D
S
V
M
---
59
HHSearch
84.97
40%
-128
- C5 -
3DAH
4
?
A:
[6-315]
--
D
G
L
M
V
F
T
G
N
A
N
P
A
L
A
Q
E
V
V
K
I
L
G
I
P
L
G
K
A
M
V
S
R
F
S
D
G
E
I
Q
V
E
I
Q
E
N
V
R
G
K
D
V
F
V
L
Q
S
T
C
A
P
T
N
D
N
L
M
E
L
M
I
M
V
D
A
L
K
R
A
S
A
G
R
I
T
A
A
I
P
Y
F
G
Y
A
R
Q
D
R
R
P
R
S
A
-
R
V
A
I
S
----
A
K
V
V
A
N
M
L
E
I
A
G
V
E
R
I
I
T
M
D
L
H
A
D
Q
I
Q
G
F
F
D
I
P
V
D
N
I
Y
A
T
P
-
I
L
L
G
D
L
R
K
Q
N
--
Y
-
P
D
L
-
L
V
V
S
P
D
V
G
G
V
V
R
A
R
A
L
A
K
Q
L
N
C
D
L
A
I
------------------------
E
G
R
T
C
V
I
M
D
D
M
V
D
T
A
G
T
L
C
K
A
A
Q
V
L
K
E
R
G
A
K
Q
V
F
A
Y
A
T
H
P
V
L
S
-
G
G
A
A
D
R
I
A
A
S
A
L
D
E
L
V
V
T
D
T
I
P
L
-
S
A
E
S
--
L
A
C
P
K
I
R
A
L
S
S
A
G
L
L
A
E
T
F
S
R
I
R
R
G
D
S
V
M
S
L
-
43
PsiBlast_CBE
72.54
31%
-138
- C5 -
1U9Z
3
KPRS_METJA
C:
[1-266]
----
M
I
V
V
S
G
S
Q
S
Q
N
L
A
F
K
V
A
K
L
L
N
T
K
L
T
R
V
E
Y
K
R
F
P
D
N
E
I
Y
V
R
I
V
D
E
I
N
D
D
E
A
V
I
I
N
T
-
Q
K
N
Q
N
D
A
I
V
E
T
I
L
L
C
D
A
L
R
D
E
G
V
K
K
I
T
L
V
A
P
Y
L
A
Y
A
R
Q
D
K
K
F
N
-
P
-
G
E
A
I
S
IRAL
A
K
I
Y
S
N
I
V
-----
D
K
L
I
T
I
N
P
H
E
T
H
I
K
D
F
F
T
I
P
F
I
Y
G
D
A
V
P
-
K
L
A
E
Y
V
K
D
K
L
N
----
D
P
-
I
V
L
A
P
D
K
G
A
L
E
F
A
K
T
A
S
K
I
L
N
A
E
Y
D
Y
L
E
--------------
I
A
P
K
T
L
D
A
K
D
R
D
V
F
I
V
D
D
I
I
S
T
G
G
T
M
A
T
A
V
K
L
L
K
E
Q
G
A
K
K
I
I
A
A
C
V
H
P
V
L
I
-
G
D
A
L
N
K
L
Y
S
A
G
V
E
E
V
V
G
T
D
T
------------------------------------------
42
PsiBlast_CBE
72.45
31%
-137
- C5 -
1U9Z
3
KPRS_METJA
D:
[1-266]
----
M
I
V
V
S
G
S
Q
S
Q
N
L
A
F
K
V
A
K
L
L
N
T
K
L
T
R
V
E
Y
K
R
F
P
D
N
E
I
Y
V
R
I
V
D
E
I
N
D
D
E
A
V
I
I
N
T
-
Q
K
N
Q
N
D
A
I
V
E
T
I
L
L
C
D
A
L
R
D
E
G
V
K
K
I
T
L
V
A
P
Y
L
A
Y
A
R
Q
D
K
K
F
N
-
P
-
G
E
A
I
S
IRAL
A
K
I
Y
S
N
I
V
-----
D
K
L
I
T
I
N
P
H
E
T
H
I
K
D
F
F
T
I
P
F
I
Y
G
D
A
V
P
-
K
L
A
E
Y
V
K
D
K
L
N
----
D
P
-
I
V
L
A
P
D
K
G
A
L
E
F
A
K
T
A
S
K
I
L
N
A
E
Y
D
Y
L
E
--------------
I
A
P
K
T
L
D
A
K
D
R
D
V
F
I
V
D
D
I
I
S
T
G
G
T
M
A
T
A
V
K
L
L
K
E
Q
G
A
K
K
I
I
A
A
C
V
H
P
V
L
I
-
G
D
A
L
N
K
L
Y
S
A
G
V
E
E
V
V
G
T
D
T
------------------------------------------
18
PsiBlast_PDB
72.38
31%
-138
- C5 -
1U9Z
3
KPRS_METJA
A:
[1-266]
----
M
I
V
V
S
G
S
Q
S
Q
N
L
A
F
K
V
A
K
L
L
N
T
K
L
T
R
V
E
Y
K
R
F
P
D
N
E
I
Y
V
R
I
V
D
E
I
N
D
D
E
A
V
I
I
N
T
-
Q
K
N
Q
N
D
A
I
V
E
T
I
L
L
C
D
A
L
R
D
E
G
V
K
K
I
T
L
V
A
P
Y
L
A
Y
A
R
Q
D
K
K
F
N
-
P
-
G
E
A
I
S
I
R
A
L
A
K
I
Y
S
N
I
V
-----
D
K
L
I
T
I
N
P
H
E
T
H
I
K
D
F
F
T
I
P
F
I
Y
G
D
A
V
P
-
K
L
A
E
Y
V
K
D
K
L
N
----
D
P
-
I
V
L
A
P
D
K
G
A
L
E
F
A
K
T
A
S
K
I
L
N
A
E
Y
D
Y
L
E
--------------
I
A
P
K
T
L
D
A
K
D
R
D
V
F
I
V
D
D
I
I
S
T
G
G
T
M
A
T
A
V
K
L
L
K
E
Q
G
A
K
K
I
I
A
A
C
V
H
P
V
L
I
-
G
D
A
L
N
K
L
Y
S
A
G
V
E
E
V
V
G
T
D
T
------------------------------------------
44
PsiBlast_CBE
72.29
31%
-137
- C5 -
1U9Z
3
KPRS_METJA
B:
[1-266]
----
M
I
V
V
S
G
S
Q
S
Q
N
L
A
F
K
V
A
K
L
L
N
T
K
L
T
R
V
E
Y
K
R
F
P
D
N
E
I
Y
V
R
I
V
D
E
I
N
D
D
E
A
V
I
I
N
T
-
Q
K
N
Q
N
D
A
I
V
E
T
I
L
L
C
D
A
L
R
D
E
G
V
K
K
I
T
L
V
A
P
Y
L
A
Y
A
R
Q
D
K
K
F
N
-
P
-
G
E
A
I
S
IRAL
A
K
I
Y
S
N
I
V
-----
D
K
L
I
T
I
N
P
H
E
T
H
I
K
D
F
F
T
I
P
F
I
Y
G
D
A
V
P
-
K
L
A
E
Y
V
K
D
K
L
N
----
D
P
-
I
V
L
A
P
D
K
G
A
L
E
F
A
K
T
A
S
K
I
L
N
A
E
Y
D
Y
L
E
--------------
I
A
P
K
T
L
D
A
K
D
R
D
V
F
I
V
D
D
I
I
S
T
G
G
T
M
A
T
A
V
K
L
L
K
E
Q
G
A
K
K
I
I
A
A
C
V
H
P
V
L
I
-
G
D
A
L
N
K
L
Y
S
A
G
V
E
E
V
V
G
T
D
T
------------------------------------------
20
PsiBlast_PDB
70.17
30%
-99
- C5 -
3LPN
5
KPRS_THEVO
A:
[1-265]
----
M
K
I
I
A
L
R
S
S
L
K
L
A
A
R
I
A
E
E
L
K
T
E
P
V
M
P
D
E
R
R
F
P
D
G
E
L
Y
L
R
Y
D
E
D
L
T
G
H
N
I
F
I
I
G
--
N
T
H
S
D
A
E
V
M
E
M
I
L
T
L
S
A
I
Q
D
Y
R
T
K
S
V
N
I
I
A
P
Y
Y
G
Y
A
R
Q
H
Q
R
Y
K
-
N
-
G
E
P
I
S
----
S
Q
I
L
T
E
-
I
Y
S
S
Y
S
N
S
I
A
T
V
D
I
H
D
E
K
T
L
S
Y
S
K
V
K
F
S
D
L
H
A
-----
N
D
A
I
V
R
Y
Y
K
-
N
-
V
D
V
D
Y
V
V
S
P
D
D
G
G
L
A
R
V
A
D
I
S
A
K
L
G
K
K
H
F
F
I
E
-
K
-
K
R
I
D
D
R
T
V
E
M
K
V
P
N
V
--
D
V
N
G
K
K
L
L
I
V
D
D
I
I
S
T
G
G
T
I
A
K
S
S
G
L
L
R
E
K
G
A
S
K
I
Y
V
S
A
V
H
G
L
F
V
N
G
S
E
N
K
I
L
Q
N
A
D
--
E
I
H
V
T
D
T
V
E
----------------------------------------