@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1462: (2016-03-25 )
MSEPFKSGFVAIVGRPNVGKSTLLNHIIGQKIAIMSDKAQTTRNKVQGVYTTDESQIIFIDTPGIHKPKHKLGDFMVKIALNTFQEVDLIYFVIDASTGFGRGDEFIIEKLKNVQTPVFLLINKIDLIAPEDLFKLIEQYRDLMDFDEIIPISALQGNNVPNLLEQTNANLEIGPMYYPKDQITDHPERFIISELIREQVLQLTREEVPHSVAVVIEGIEKNPKTEKLTINATIIVERSTQKGIIIGKQGQMLKQIGMRARKEIERLLGSKVFLEIWVKVQKNWRDKEHYLQDYGFDREEY
Atome Classification :
(26 SA)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........-10........20........30........40........50-.-.......60...-----.-.-..-.-70-.-----...--.....---80........90........100.......-110..--.--.....120.......-130-.--.----......-140.---..-...--.150.......160.......170.......180.-......190.......200.......210.......---220..-.....230.......240.......250.......260.......270.......280.......290.......300
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEPFKS
G
F
-
V
A
I
VGRPNV
G
K
S
T
L
L
N
H
I
IG
Q
K
I
A
I
MSDK
A
Q
TTRNK
V
Q
G
V
Y
T-T-DE
S
Q
I
I
F
I
DTPG-----I-H-K
P
-
K
-
H
--
K
-----
L
G
D
--
F
M
V
K
I
---
A
L
NTFQE
V
D
L
I
Y
F
V
I
DASTGFGR
G
D
E
F
I
I
E
-
K
-
L
KN--V--QT
P
V
F
L
L
I
N
KIDLI
A
-
P
-
E
-
D
--
L
----
F
K
L
I
E
Q
-
Y
R
D
L
---
M
D
-
F
D
E--IIPISALQGNNV
P
N
L
L
E
QTNAN
L
E
IGPMYYPKDQI-TD
H
P
E
R
F
I
I
S
E
L
I
R
E
Q
V
L
Q
L
T
R
E
EVP
H
S
V
A
V
V
I
EGI---EKNPK-T
E
K
L
T
I
N
A
T
I
I
V
ERSTQK
G
I
I
IGKQ
G
Q
M
L
K
Q
I
G
M
R
A
R
K
E
I
E
R
L
LG
S
K
V
F
L
E
I
W
V
K
V
Q
KNWR
D
K
E
H
Y
L
Q
D
YGFDREEY
63
HHSearch
96.06
48%
-119
- C2 -
3IEV
4
ERA_AQUAE
A:
[7-307]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
M
K
V
G
Y
-
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
V
S
I
I
S
P
K
A
G
T
T
R
M
R
V
L
G
V
K
N
-
I
P
N
E
A
Q
I
I
F
L
D
T
P
G
-----
I
-
Y
-
E
P
-
K
-
K
SD
V
-----
L
G
H
--
S
M
V
E
I
---
A
K
Q
S
L
E
E
A
D
V
I
L
F
M
I
D
A
T
E
G
W
R
P
R
D
E
E
I
Y
Q
N
F
-
I
K
P
--
L
--
N
K
P
V
I
V
V
I
N
K
I
D
K
I
G
-
P
-
A
-
K
N-
V
----
L
P
L
I
D
E
-
I
H
K
K
---
H
P
E
L
T
E
--
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
Y
L
P
E
G
E
P
L
F
P
E
D
M
I
-
T
D
L
P
L
R
L
L
A
A
E
I
V
R
E
K
A
M
M
L
T
R
E
E
V
P
T
S
I
A
V
K
I
N
E
I
---
K
P
G
D
A
N
P
N
M
L
V
I
K
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
P
V
Y
L
E
L
W
V
K
V
V
P
D
W
R
R
R
P
E
Y
V
R
L
F
G
Y
A
----
2
PsiBlast_PDB
95.52
47%
-126
- C2 -
3R9W
8
ERA_AQUAE
A:
[7-305]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
V
G
Y
-
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
V
S
I
I
S
P
K
A
G
T
T
R
M
R
V
L
G
V
K
N
I
P
-
N
E
A
Q
I
I
F
L
D
T
P
G
-----
I
-
Y
-
E
P
-
K
-
K
--
S
D
V
---
L
G
H
--
S
M
V
E
I
---
A
K
Q
S
L
E
E
A
D
V
I
L
F
M
I
D
A
T
E
G
W
R
P
R
D
E
E
I
Y
Q
-
N
F
I
K
P
--
L
--
N
K
P
V
I
V
V
I
N
K
I
D
K
I
G
-
P
A
K
-
N
--
V
----
L
P
L
I
D
E
I
H
K
K
H
---
P
E
-
L
T
E
--
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
Y
L
P
E
G
E
P
L
F
P
E
D
M
I
-
T
D
L
P
L
R
L
L
A
A
E
I
V
R
E
K
A
M
M
L
T
R
E
E
V
P
T
S
I
A
V
K
I
N
E
I
K
P
G
D
A
N
P
N
-
M
--
L
V
I
K
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
P
V
Y
L
E
L
W
V
K
V
V
P
D
W
R
R
R
P
E
Y
V
R
L
F
G
Y
-----
1
PsiBlast_PDB
95.07
47%
-123
- C2 -
3IEV
4
ERA_AQUAE
A:
[8-306]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
V
G
Y
-
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
V
S
I
I
S
P
K
A
G
T
T
R
M
R
V
L
G
V
K
N
I
P
-
N
E
A
Q
I
I
F
L
D
T
P
G
-----
I
-
Y
-
E
P
-
K
-
K
--
S
D
V
---
L
G
H
--
S
M
V
E
I
---
A
K
Q
S
L
E
E
A
D
V
I
L
F
M
I
D
A
T
E
G
W
R
P
R
D
E
E
I
Y
Q
-
N
F
I
K
P
--
L
--
N
K
P
V
I
V
V
I
N
K
I
D
K
I
G
-
P
A
K
-
N
--
V
----
L
P
L
I
D
E
I
H
K
K
H
---
P
E
-
L
T
E
--
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
Y
L
P
E
G
E
P
L
F
P
E
D
M
I
-
T
D
L
P
L
R
L
L
A
A
E
I
V
R
E
K
A
M
M
L
T
R
E
E
V
P
T
S
I
A
V
K
I
N
E
I
KPG
D
A
N
P
N
-
M
--
L
V
I
K
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
P
V
Y
L
E
L
W
V
K
V
V
P
D
W
R
R
R
P
E
Y
V
R
L
F
G
Y
-----
3
PsiBlast_PDB
94.48
47%
-120
- C2 -
3R9X
4
ERA_AQUAE
A:
[7-305]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
V
G
Y
-
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
V
S
I
I
S
P
K
A
G
T
T
R
M
R
V
L
G
V
K
N
I
P
-
N
E
A
Q
I
I
F
L
D
T
P
G
-----
I
-
Y
-
E
P
-
K
-
K
--
S
D
V
---
L
G
H
--
S
M
V
E
I
---
A
K
Q
S
L
E
E
A
D
V
I
L
F
M
I
D
A
T
E
G
W
R
P
R
D
E
E
I
Y
Q
-
N
F
I
K
P
--
L
--
N
K
P
V
I
V
V
I
N
K
I
D
K
I
G
-
P
A
K
-
N
--
V
----
L
P
L
I
D
E
I
H
K
K
H
---
P
E
-
L
T
E
--
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
Y
L
P
E
G
E
P
L
F
P
E
D
M
I
-
T
D
L
P
L
R
L
L
A
A
E
I
V
R
E
K
A
M
M
L
T
R
E
E
V
P
T
S
I
A
V
K
I
N
E
I
K
P
G
D
A
N
P
N
-
M
--
L
V
I
K
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
P
V
Y
L
E
L
W
V
K
V
V
P
D
W
R
R
R
P
E
Y
V
R
L
F
G
Y
-----
22
PsiBlast_CBE
88.26
40%
-121
- C2 -
1EGA
2
ERA_ECOLI
B:
[8-296]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
G
F
-
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
-----
L
-
H
M
E
E
-
K
-
R
--
A
-----
I
N
R
--
L
M
N
K
A
---
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
-
T
R
W
T
P
D
D
E
M
V
L
N
-
K
-
L
R
E
--
G
--
K
A
P
V
I
L
A
V
N
K
V
D
N
V
Q
-
E
-
K
A
D
--
L
----
L
P
H
L
Q
F
-
L
A
S
Q
---
M
N
-
F
L
D
--
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
---
V
S
N
E
R
-
G
-
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
G
------
6
PsiBlast_PDB
88.21
40%
-121
- C2 -
3IEU
7
ERA_ECOLI
A:
[8-296]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
G
F
-
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
-----
L
-
H
M
E
E
-
K
-
R
--
A
-----
I
N
R
--
L
M
N
K
A
---
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
-
T
R
W
T
P
D
D
E
M
V
L
N
-
K
-
L
R
E
--
G
--
K
A
P
V
I
L
A
V
N
K
V
D
N
V
Q
-
E
-
K
A
D
--
L
----
L
P
H
L
Q
F
-
L
A
S
Q
---
M
N
-
F
L
D
--
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
---
V
S
N
E
R
-
G
-
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
G
------
21
PsiBlast_CBE
87.90
40%
-121
- C2 -
3IEU
9
ERA_ECOLI
B:
[8-296]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
G
F
-
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
-----
L
-
H
M
E
E
-
K
-
R
--
A
-----
I
N
R
--
L
M
N
K
A
---
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
-
T
R
W
T
P
D
D
E
M
V
L
N
-
K
-
L
R
E
--
G
--
K
A
P
V
I
L
A
V
N
K
V
D
N
V
Q
-
E
-
K
A
D
--
L
----
L
P
H
L
Q
F
-
L
A
S
Q
---
M
N
-
F
L
D
--
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
---
V
S
N
E
R
-
G
-
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
G
------
62
HHSearch
87.36
38%
-101
- C2 -
1WF3
4
ERA_THET8
A:
[3-298]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
K
T
Y
S
G
F
-
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
V
K
V
A
P
I
S
P
R
P
Q
T
T
R
K
R
L
R
G
I
L
T
-
E
-
G
R
R
Q
I
V
F
V
D
T
P
G
-----
L
-
H
-
K
P
-
M
-
D
--
A
-----
L
G
E
--
F
M
D
Q
E
---
V
Y
E
A
L
A
D
V
N
A
V
V
W
V
V
D
L
R
H
P
P
T
P
E
D
E
L
V
A
R
-
A
-
L
K
P
LV
G
--
K
V
P
I
L
L
V
G
N
K
L
D
A
A
K
-
Y
-
P
-
E
--------
E
A
M
K
A
-
Y
H
E
L
---
L
P
-
E
A
E
--
P
R
M
L
S
A
L
D
E
R
Q
V
A
E
L
K
A
D
L
L
A
L
M
P
E
G
P
F
F
Y
P
E
D
Y
A
K
S
D
Q
T
F
G
E
W
V
A
E
I
L
R
E
E
A
M
K
R
L
W
H
E
V
P
Y
A
V
A
T
K
V
E
E
V
---
A
E
R
E
--
N
G
V
L
Y
I
K
A
I
L
Y
V
E
R
P
S
Q
K
A
I
V
I
G
E
G
G
R
K
I
K
E
I
G
Q
A
T
R
K
Q
L
E
A
L
L
G
K
K
V
Y
L
D
L
E
V
K
V
Y
P
D
W
R
K
D
P
E
A
L
R
E
L
G
Y
R
S
---
8
PsiBlast_PDB
86.82
38%
-108
- C2 -
1WF3
4
ERA_THET8
A:
[3-296]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
K
T
Y
S
G
F
-
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
V
K
V
A
P
I
S
P
R
P
Q
T
T
R
K
R
L
R
G
I
L
T
-
E
-
G
R
R
Q
I
V
F
V
D
T
P
G
-----
L
-
H
-
K
P
-
M
-
D
--
A
-----
L
G
E
--
F
M
D
Q
E
---
V
Y
E
A
L
A
D
V
N
A
V
V
W
V
V
D
L
R
H
P
P
T
P
E
D
E
L
V
A
R
-
A
-
L
K
P
--
L
VG
K
V
P
I
L
L
V
G
N
K
L
D
A
A
K
Y
P
-
E
-
E
--
A
----
M
K
---
A
-
Y
H
E
L
---
L
P
-
E
A
E
--
P
R
M
L
S
A
L
D
E
R
Q
V
A
E
L
K
A
D
L
L
A
L
M
P
E
G
P
F
F
Y
P
E
D
Y
A
K
S
D
Q
T
F
G
E
W
V
A
E
I
L
R
E
E
A
M
K
R
L
W
H
E
V
P
Y
A
V
A
T
K
V
E
E
V
---
A
E
R
-
E
-
N
G
V
L
Y
I
K
A
I
L
Y
V
E
R
P
S
Q
K
A
I
V
I
G
E
G
G
R
K
I
K
E
I
G
Q
A
T
R
K
Q
L
E
A
L
L
G
K
K
V
Y
L
D
L
E
V
K
V
Y
P
D
W
R
K
D
P
E
A
L
R
E
L
G
Y
-----
4
PsiBlast_PDB
86.08
40%
-118
- C2 -
1EGA
3
ERA_ECOLI
A:
[8-295]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
G
F
-
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
-----
L
-
H
M
E
E
-
K
-
R
--
A
-----
I
N
R
--
L
M
N
K
A
---
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
-
T
R
W
T
P
D
D
E
M
V
L
N
-
K
-
L
R
E
--
G
--
K
A
P
V
I
L
A
V
N
K
V
D
N
V
Q
-
E
-
K
A
D
--
L
----
L
P
H
L
Q
F
-
L
A
S
Q
---
M
N
-
F
L
D
--
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
---
V
S
N
E
R
-
G
-
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
-------
61
HHSearch
85.26
39%
-114
- C2 -
1EGA
3
ERA_ECOLI
A:
[4-295]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
S
Y
C
G
F
-
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
-----
L
-
H
-
M
E
-
E
K
R
--
A
-----
I
N
R
--
L
M
N
K
A
---
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
T
R
-
W
T
P
D
D
E
M
V
L
N
-
K
-
L
R
E
--
G
--
K
A
P
V
I
L
A
V
N
K
V
D
N
V
Q
-
E
-
K
-
A
D-
L
----
L
P
H
L
Q
F
-
L
A
S
Q
---
M
N
-
F
L
D
--
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
---
V
S
N
E
--
R
G
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
-------
51
Fugue
66.35
38%
-106
- C2 -
1EGA
3
ERA_ECOLI
A:
[4-182]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
S
Y
C
G
F
-
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
-----
L
H
M
-
E
E
-
K
-
R
--
A
-----
I
N
R
--
L
M
N
K
A
---
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
T
R
-
W
T
P
D
D
E
M
V
L
N
-
K
-
L
R
E
--
G
--
K
A
P
V
I
L
A
V
N
K
V
D
N
V
Q
E
K
-
A
-
D
--
L
----
L
P
H
L
Q
F
-
L
A
S
Q
---
M
N
-
F
L
D
--
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
------------------------------------------------------------------------------------------------------------------------------
53
Fugue
58.84
23%
-91
- C2 -
1XZP
3
MNME_THEMA
A:
[27-482]
SSVDKL
M
D
T
I
V
A
VATPPGKGA
I
A
I
L
R
L
S
GPD
S
W
K
I
V
Q
K
H
L
R
T
R
SKIVPRKA
I
H
G
W
I
H
ENGED
V
D
E
V
V
V
V
F
Y
K
SPKSYTG
E
D
M
V
E
V
M
C
HGG
P
L
V
V
K
K
L
L
D
L
F
L
K
S
GARMAEPG
E
F
T
K
R
A
F
L
N
GKMD
L
T
S
A
E
A
V
R
D
L
I
E
AKS
E
T
S
L
K
L
S
L
R
N
L
K
G
G
L
R
D
F
V
D
S
L
R
R
E
L
I
E
V
L
A
E
I
R
V
E
L
D
Y
PDEIETN
T
G
E
V
V
T
R
L
E
R
I
K
E
K
L
T
E
E
L
K
K
A
D
A
G
I
L
L
N
R
G
L
R
M
V
I
V
G
K
P
N
V
G
K
S
T
L
L
N
R
L
L
N
E
D
R
A
I
V
T
D
I
P
G
T
T
R
D
V
I
S
E
E
I
V
-
I
-
R
G
I
L
F
R
I
V
D
T
A
G
-----
V
-
R
-
S
E
T
N
-
D
--
L
-----
V
E
R
--
L
G
I
E
R
---
T
L
Q
E
I
E
K
A
D
I
V
L
F
V
L
D
A
S
S
P
L
D
E
E
D
R
K
I
L
E
-
R
-
I
K
N
------
K
R
Y
L
V
V
I
N
K
V
D
V
V
E
-
K
-
I
-
N
--
E
----
E
E
I
K
N
K
-
L
G
T
D
-------
R
H
--
M
V
K
I
S
A
L
K
G
E
G
L
E
K
L
E
E
S
I
Y
R
E
T
---------
Q
E
I
-
F
E
R
G
S
D
S
L
I
T
N
L
R
Q
K
Q
L
L
E
N
V
K
G
H
L
E
D
A
I
K
S
L
K
E
G
---------------------------------
M
P
V
D
M
A
S
I
D
L
E
R
A
L
N
L
L
D
E
V
T
G
R
S
F
R
E
D
L
L
D
T
I
F
S
N
F
C
V
G
K
-------------
20
PsiBlast_PDB
58.73
28%
-119
- C2 -
3PQC
2
ENGB_THEMA
A:
[21-186]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
K
-
G
E
-
V
A
F
V
G
R
S
N
V
G
K
S
S
L
L
N
A
L
F
N
R
K
I
A
F
V
S
K
T
P
G
K
T
R
S
--
I
N
F
Y
L
-
V
-
N
-
S
K
Y
Y
F
V
D
L
P
G
YGYAK
V
-
S
-
K
K
-
E
-
R
--
M
-----
L
W
K
--
R
L
V
E
D
---
Y
F
K
N
R
W
S
L
Q
M
V
F
L
L
V
D
G
R
I
P
P
Q
D
S
D
L
M
M
V
E
-
W
-
M
K
S
--
L
--
N
I
P
F
T
I
V
L
T
K
M
D
K
V
K
-
M
-
S
-
E
--
R
----
A
K
K
L
E
E
-
H
R
K
V
---
F
S
K
Y
G
E
Y
T
I
I
P
T
S
S
V
T
G
E
G
I
S
E
L
L
D
---------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
58.53
32%
-99
- C2 -
1MKY
3
DER_THEMA
A:
[4-182]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
I
V
G
R
P
N
V
G
K
S
T
L
F
N
K
L
V
K
--------------
D
P
V
Q
D
T
V
E
-
W
-
Y
G
K
T
F
K
L
V
D
T
C
G
-----
V
F
D
-
N
P
-
Q
-
D
--
I
-----
I
S
Q
--
K
M
K
E
V
---
T
L
N
M
I
R
E
A
D
L
V
L
F
V
V
D
G
K
R
G
I
T
K
E
D
E
S
L
A
D
-
F
-
L
R
K
--
S
--
T
V
D
T
I
L
V
A
N
K
A
E
N
L
R
-
E
-
F
-
E
--
R
----
E
V
K
P
E
L
-
Y
S
-----
L
G
-
F
G
E
--
P
I
P
V
S
A
E
H
N
I
N
L
D
T
M
L
E
T
I
I
K
K
L
E
--------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
58.15
34%
-142
- C2 -
4DCV
-
DER_BACSU
A:
[26-183]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
A
I
V
G
R
P
N
V
G
K
S
T
I
F
N
R
I
A
G
E
R
I
S
-----------
R
I
Y
S
S
A
E
-
W
-
L
N
Y
D
F
N
L
I
D
T
G
G
--------------------------P-
F
L
A
Q
I
R
Q
Q
A
E
I
A
M
D
E
A
D
V
I
I
F
M
V
N
G
R
E
G
V
T
A
A
D
E
E
V
A
K
-
I
-
L
Y
R
--
T
--
K
K
P
V
V
L
A
V
N
K
L
--------------------
Y
D
F
-
Y
S
-----
L
G
-
F
G
E
--
P
Y
P
I
S
G
T
H
G
L
G
L
G
D
L
L
D
---------------------------------------------------------------------------------------------------------------------------------------------
66
HHSearch
58.00
27%
-118
- C2 -
1MKY
3
DER_THEMA
A:
[178-355]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
A
I
K
-
V
A
I
V
G
R
P
N
V
G
K
S
T
L
F
N
A
I
L
N
K
E
R
A
L
V
S
P
I
P
------
V
D
D
E
V
F
-
I
-
D
G
R
K
Y
V
F
V
D
T
A
G
-----
L
------------------
E
K
--
Y
S
N
Y
R
---
V
V
D
S
I
E
K
A
D
V
V
V
I
V
L
D
A
T
Q
G
I
T
R
Q
D
Q
R
M
A
G
-
L
-
M
E
R
--
R
--
G
R
A
S
V
V
V
F
N
K
W
D
L
V
V
-
H
-
R
-
E
KR
Y
----
D
E
F
T
K
L
-
F
R
E
K
L
YF
I
D
-
Y
S
P
--
L
I
F
T
S
A
D
K
G
W
N
I
D
R
M
I
D
A
M
N
L
A
Y
A
S
-------------------------------------------------------------------------------------------------------------------------------------
75
HHSearch
57.71
28%
-96
- C2 -
2DYK
1
?
A:
[2-160]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
K
-
V
V
I
V
G
R
P
N
V
G
K
S
S
L
F
N
R
L
L
K
K
R
S
-----------
D
L
K
E
G
V
V
E
-
T
-
D
R
G
R
F
L
L
V
D
T
G
G
-----
L
-
W
-
S
G
-
D
-
K
--------
W
E
K
--
K
I
Q
E
K
---
V
D
R
A
L
E
D
A
E
V
V
L
F
A
V
D
G
R
A
E
L
T
Q
A
D
Y
E
V
A
E
-
Y
-
L
R
R
--
K
--
G
K
P
V
I
L
V
A
T
K
V
D
D
P
K
-
H
-
E
-
L
--
Y
----
L
G
--
P
L
-
Y
--
G
---
L
G
-
F
G
D
--
P
I
P
T
S
S
E
H
A
R
G
L
E
E
L
L
E
A
I
W
E
R
L
---------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
57.45
28%
-101
- C2 -
2DYK
1
?
A:
[4-154]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
V
I
V
G
R
P
N
V
G
K
S
S
L
F
N
R
L
L
K
K
R
S
-----------
D
L
K
E
G
V
V
E
-
T
-
D
R
G
R
F
L
L
V
D
T
G
G
-----
L
-
W
-
S
G
-
D
-
K
--
W
-----
E
K
K
--
I
Q
E
K
V
---
D
-
R
A
L
E
D
A
E
V
V
L
F
A
V
D
G
R
A
E
L
T
Q
A
D
Y
E
V
A
E
-
Y
-
L
R
R
--
K
--
G
K
P
V
I
L
V
A
T
K
V
D
--
D
-
P
-
K
-
H
--
E
----
L
Y
L
G
P
L
-
Y
G
-----
L
G
-
F
G
D
--
P
I
P
T
S
S
E
H
A
R
G
L
E
E
L
L
E
---------------------------------------------------------------------------------------------------------------------------------------------
76
HHSearch
57.26
27%
-95
- C2 -
3PQC
2
ENGB_THEMA
A:
[19-193]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
P
P
L
K
G
E
-
V
A
F
V
G
R
S
N
V
G
K
S
S
L
L
N
A
L
F
N
R
K
I
A
F
V
S
K
T
P
G
K
T
R
S
I
N
F
Y
----
L
-
V
N
S
K
Y
Y
F
V
D
L
P
G
-----
Y
-
G
-
Y
A
-
K
-
V
--
S
K
K
E
R
M
L
W
K
--
R
L
V
E
D
---
Y
F
K
N
R
W
S
L
Q
M
V
F
L
L
V
D
G
R
I
P
P
Q
D
S
D
L
M
M
V
E
-
W
-
M
K
S
--
L
--
N
I
P
F
T
I
V
L
T
K
M
D
K
V
K
-
M
-
S
-
E
--
R
A
K
K
L
E
E
H
R
K
V
-
F
S
-
K
---
Y
G
-
E
Y
T
--
I
I
P
T
S
S
V
T
G
E
G
I
S
E
L
L
D
L
I
S
T
L
L
K
--------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
57.08
34%
-138
- C2 -
4KYU
5
DER_BACSU
B:
[6-157]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
A
I
V
G
R
P
N
V
G
K
S
T
I
F
N
R
I
A
-----------------
I
Y
S
S
A
E
-
W
--
N
Y
D
F
N
L
I
D
T
G
G
-----
I
-----------
D
-----
I
G
D
EP
F
L
A
Q
I
R
Q
Q
A
E
I
A
M
D
E
A
D
V
I
I
F
M
V
N
G
R
E
G
V
T
A
A
D
E
E
V
A
K
-
I
-
L
Y
R
--
T
--
K
K
P
V
V
L
A
V
N
K
L
D
--
N
-
T
-
E
-
M
--
R
----
A
N
I
Y
D
F
-
Y
S
-----
L
G
-
F
G
E
--
P
Y
P
I
S
G
T
H
G
L
G
L
G
D
L
L
D
---------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
56.66
34%
-141
- C2 -
4DCU
1
DER_BACSU
A:
[26-183]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
A
I
V
G
R
P
N
V
G
K
S
T
I
F
N
R
I
A
G
E
R
I
S
-----------
R
I
Y
S
S
A
E
-
W
-
L
N
Y
D
F
N
L
I
D
T
G
G
--------------------------P-
F
L
A
Q
I
R
Q
Q
A
E
I
A
M
D
E
A
D
V
I
I
F
M
V
N
G
R
E
G
V
T
A
A
D
E
E
V
A
K
-
I
-
L
Y
R
--
T
--
K
K
P
V
V
L
A
V
N
K
L
--------------------
Y
D
F
-
Y
S
-----
L
G
-
F
G
E
--
P
Y
P
I
S
G
T
H
G
L
G
L
G
D
L
L
D
---------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
56.24
34%
-145
- C2 -
2HJG
1
DER_BACSU
A:
[6-166]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
A
I
V
G
R
P
N
V
G
K
S
T
I
F
N
R
I
A
G
E
R
I
S
-----------
R
I
Y
S
S
A
E
-
W
-
L
N
Y
D
F
N
L
I
D
-----------------------------P-
F
L
A
Q
I
R
Q
Q
A
E
I
A
M
D
E
A
D
V
I
I
F
M
V
N
G
R
E
G
V
T
A
A
D
E
E
V
A
K
-
I
-
L
Y
R
--
T
--
K
K
P
V
V
L
A
V
N
K
L
D
--
N
--------------
N
I
Y
D
F
-
Y
S
-----
L
G
-
F
G
E
--
P
Y
P
I
S
G
T
H
G
L
G
L
G
D
L
L
D
---------------------------------------------------------------------------------------------------------------------------------------------
70
HHSearch
55.21
30%
-115
- C2 -
3GEH
3
MNME_NOSS1
A:
[222-385]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
T
G
L
K
-
V
A
I
V
G
R
P
N
V
G
K
S
S
L
L
N
A
W
S
Q
S
D
R
A
I
V
T
D
L
P
G
T
T
R
D
V
V
E
S
Q
L
V
-
V
-
G
G
I
P
V
Q
V
L
D
-----------------------------------------
Q
A
A
N
T
A
D
L
V
L
L
T
I
D
A
A
T
G
W
T
T
G
D
Q
E
I
Y
E
-
Q
-
V
----
K
--
H
R
P
L
I
L
V
M
N
K
I
D
L
V
E
-
K
-
Q
-
L
--
I
----
T
S
-----
L
E
Y
P
---
E
N
-
I
T
Q
--
I
V
H
T
A
A
A
Q
K
Q
G
I
D
S
L
E
T
A
I
L
E
I
V
Q
T
G
------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
55.13
34%
-113
- C2 -
4KYU
5
DER_BACSU
A:
[6-157]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
A
I
V
G
R
P
N
V
G
K
S
T
I
F
N
R
I
A
G
E
R
I
----------
R
D
R
I
Y
S
S
A
E
-
W
-
L
N
Y
D
F
N
L
I
D
T
G
G
-----
I
-----------
D
-----
I
G
D
EP
F
L
A
Q
I
R
Q
Q
A
E
I
A
M
D
E
A
D
V
I
I
F
M
V
N
G
R
E
G
V
T
A
A
D
E
E
V
A
K
-
I
-
L
Y
R
--
T
--
K
K
P
V
V
L
A
V
N
K
L
D
--
N
-
T
-
E
-
M
--
R
----
A
N
I
Y
D
F
-
Y
S
-----
L
G
-
F
G
E
--
P
Y
P
I
S
G
T
H
G
L
G
L
G
D
L
L
D
---------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
51.80
37%
-126
- C2 -
3GEH
2
MNME_NOSS1
A:
[219-343]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
L
R
T
G
L
K
V
A
I
V
G
R
P
N
V
G
K
S
S
L
L
N
A
W
S
Q
S
D
R
A
I
V
T
D
L
P
G
T
T
R
D
V
V
E
S
Q
L
V
-
V
-
G
G
I
P
V
Q
V
L
D
-----------------------------------------
Q
A
A
N
T
A
D
L
V
L
L
T
I
D
A
A
T
G
W
T
T
G
D
Q
E
I
Y
E
-
Q
-
V
K
H
------
R
P
L
I
L
V
M
N
K
I
D
L
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------