@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1631: (2016-03-27 )
MEILLQKVYDQENLSKEEMNIIATEIFEGRLSKTKMAAFLMALKVKGETAEEMAGIAQAMQQVAIQVAFPAGTAMDNCGTGGDKSNSFNISTTSAFVLAAAGIPVAKHGNRSISSRSGSADVCQELGIDINLRPEDMTYLLEKVGIAFLFAPHVHPNMKYVMDVRKELGTPTIFNLIGPLTNPVHLETQLMGIYRRDLLEQTAEVLGQLGRKRAVVLNGAGFMDEASLAGENHYALYENGEVHLYTLRPEDVGLTSYPLEAITGGDAKENAAILRSVLEGEPGAYLDTVLLNAGFGLFANGKVETVQEGVDLAKDLISSGLAKQKLADLITYQKEVLAK
Atome Classification :
(40 SA)
-.........10........20........30........40........50........60........70-...----......80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270........280-........290.......300..--.-------....310.......320.......330.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-M
E
I
L
L
Q
K
VYDQENL
S
K
E
E
M
N
I
I
A
T
E
I
F
EGRL
S
K
T
K
M
A
A
F
L
M
A
LKVKGE
T
A
E
E
M
A
G
I
A
Q
A
M
Q
Q
V
A
I
Q
V
AFP--AGT----AMDNCGTGGDKSN
S
F
N
I
STT
S
A
F
V
L
A
AAGIPVAKHGNRSISSRSG
S
A
D
V
C
Q
ELG
I
D
I
NLR
P
E
D
M
T
Y
L
L
E
KV
G
I
A
F
L
FAPHVHP
N
M
K
Y
V
M
D
V
R
K
ELGT
P
T
I
F
N
L
I
GPLTNP
V
H
L
E
T
Q
L
M
G
I
Y
R
R
D
L
L
E
Q
T
A
E
V
L
G
QLGR
K
R
A
V
V
LNGAGFMD
E
A
SLAGEN
H
Y
A
L
Y
ENG
E
V
H
L
Y
T
LRPEDVGLTSYP
L
E
AITGGDA
K
E
N
A
-
A
I
L
R
S
V
LEG-E-PG
A
Y
L
D
T
V
L
L
NAGF
G
L
FANG
K
V
E
--
T
-------
V
Q
E
G
V
D
L
A
K
D
L
I
SS
G
L
A
K
Q
K
L
A
D
L
I
T
Y
Q
K
E
V
LAK
82
HHSearch
96.40
41%
-91
- C13 -
1VQU
2
TRPD2_NOSS1
A:
[27-374]
-
W
Y
L
L
L
Q
Q
L
I
D
G
E
S
L
S
R
S
Q
A
A
E
L
M
Q
G
W
L
S
E
A
V
P
P
E
L
S
G
A
I
L
T
A
L
N
F
K
G
V
S
A
D
E
L
T
G
M
A
E
V
L
Q
S
Q
S
K
M
---
T
NS
P
F
S
----
I
I
D
T
C
G
T
G
---
S
S
T
F
N
I
S
T
A
V
A
F
V
A
A
A
Y
G
V
P
V
A
K
H
G
N
R
--
S
S
L
T
G
S
A
D
V
L
E
A
L
G
V
N
L
G
A
S
P
E
K
V
Q
A
A
L
Q
E
V
G
I
T
F
L
F
A
P
G
W
H
P
A
L
K
A
V
A
T
L
R
R
T
L
R
I
R
T
V
F
N
L
L
G
P
L
V
N
P
L
R
P
T
G
Q
V
V
G
L
F
T
P
K
L
L
T
T
V
A
Q
A
L
D
N
L
G
K
Q
K
A
I
V
L
H
G
R
E
R
L
D
E
A
G
L
G
D
L
T
D
L
A
V
L
S
D
G
E
L
Q
L
T
T
I
N
P
Q
E
V
G
V
T
P
A
P
I
G
A
L
R
G
G
D
V
Q
E
N
A
-
E
I
L
K
A
V
L
Q
G
-
K
G
T
Q
A
Q
Q
D
A
V
A
L
N
A
A
L
A
L
Q
V
A
G
A
V
P
LL
D
-------
H
A
Q
G
V
S
V
A
K
E
I
L
Q
T
G
T
A
W
A
K
L
A
Q
L
V
Y
F
L
G
N
----
84
HHSearch
96.29
41%
-98
* C13 *
2ELC
4
TRPD_THET8
A:
[2-328]
---
D
A
V
K
K
A
I
L
G
E
V
L
E
E
E
E
A
Y
E
V
M
R
A
L
M
A
G
E
V
S
P
V
R
A
A
G
L
L
V
A
L
S
L
R
G
E
R
P
H
E
I
A
A
M
A
R
A
M
R
E
A
A
R
P
L
R
V
H
--
R
R
P
----
L
L
D
I
V
G
T
G
G
D
G
K
G
L
M
N
L
S
T
L
A
A
L
V
A
A
A
G
G
V
A
V
A
K
H
G
N
R
A
A
S
S
R
A
G
S
A
D
L
L
E
A
L
G
V
D
L
E
A
P
P
E
R
V
G
E
A
I
E
E
L
G
F
G
F
L
F
A
R
V
F
H
P
A
M
R
H
V
A
P
V
R
A
E
L
G
V
R
T
V
F
N
L
L
G
P
L
T
N
P
A
G
A
D
A
Y
V
L
G
V
F
S
P
E
W
L
A
P
M
A
E
A
L
E
R
L
G
A
-
R
G
L
V
V
H
G
-
E
G
A
D
E
L
V
L
-
G
E
N
R
V
V
E
V
G
K
G
---
A
Y
A
L
T
P
E
E
V
G
L
K
R
A
P
L
E
A
L
K
G
G
G
P
E
E
N
A
-
A
L
A
R
R
L
L
K
G
-
E
E
K
G
P
L
A
D
A
V
A
L
A
A
G
A
G
F
Y
A
A
G
K
T
P
--
S
-------
L
K
E
G
V
A
L
A
R
E
V
L
A
S
G
E
A
Y
L
L
L
E
R
Y
V
A
F
L
R
-----
12
PsiBlast_PDB
94.96
36%
-92
- C13 -
4N8Q
1
TRPD_MYCTU
A:
[30-370]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
-
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
RAE
W
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
---
67
PsiBlast_CBE
94.26
36%
-91
- C13 -
3QR9
1
TRPD_MYCTU
B:
[29-369]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
--
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
RAE
W
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
---
47
PsiBlast_CBE
94.16
36%
-92
- C13 -
4OWM
5
TRPD_MYCTU
B:
[30-371]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
--
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
RAE
W
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
L
--
60
PsiBlast_CBE
94.11
36%
-91
- C13 -
3R6C
5
TRPD_MYCTU
A:
[29-369]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
RAEW
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
---
69
PsiBlast_CBE
94.00
36%
-93
- C13 -
3QQS
5
TRPD_MYCTU
C:
[29-367]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
-
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
R
A
E
W
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
-----
16
PsiBlast_PDB
93.88
36%
-89
- C13 -
4GIU
9
TRPD_MYCTU
A:
[30-369]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
RAEW
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
----
56
PsiBlast_CBE
93.75
36%
-92
- C13 -
3TWP
4
TRPD_MYCTU
A:
[29-369]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
RAEW
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
---
19
PsiBlast_PDB
93.75
36%
-92
- C13 -
4OWQ
6
TRPD_MYCTU
A:
[30-370]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
RAE
W
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
---
35
PsiBlast_CBE
93.70
36%
-92
- C13 -
2BPQ
4
TRPD_MYCTU
B:
[30-372]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
-
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
----
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
----
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
AE
W
L
P
A
-
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
L
A
-
59
PsiBlast_CBE
93.65
36%
-90
- C13 -
3R6C
5
TRPD_MYCTU
B:
[29-369]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
RAEWLPA
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
---
42
PsiBlast_CBE
93.65
36%
-90
- C13 -
4OWV
3
TRPD_MYCTU
B:
[30-370]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
--
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
RAE
W
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
---
52
PsiBlast_CBE
93.61
36%
-94
- C13 -
3UU1
5
TRPD_MYCTU
C:
[29-369]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
---
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
----EWLPA--
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
---
61
PsiBlast_CBE
93.60
36%
-91
- C13 -
3QSA
4
TRPD_MYCTU
B:
[29-370]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
RAEWLPA
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
L
--
72
Fugue
93.57
38%
-98
- C13 -
1KHD
-
?
A:
[12-344]
T
H
Q
P
I
L
E
K
L
F
K
S
Q
S
M
T
Q
E
E
S
H
Q
L
F
A
A
I
V
R
G
E
L
E
D
S
Q
L
A
A
A
L
I
S
M
K
M
R
G
E
R
P
E
E
I
A
G
A
A
S
A
L
L
A
D
A
Q
P
F
P
R
P
--
D
Y
D
----
F
A
D
I
V
G
T
G
G
D
G
T
N
S
I
N
I
S
T
A
S
A
F
V
A
A
S
C
G
A
K
V
A
K
H
G
N
R
--------
C
D
L
L
Q
A
F
G
I
R
L
D
M
S
A
E
D
S
R
Q
A
L
D
D
L
N
V
C
F
L
F
A
P
Q
Y
H
T
G
F
R
H
A
M
P
V
R
Q
Q
L
K
T
R
T
I
F
N
V
L
G
P
L
I
N
P
A
R
P
P
K
A
L
I
G
V
Y
S
P
E
L
V
L
P
I
A
Q
A
L
K
V
L
G
Y
K
N
A
A
V
V
H
G
G
G
-
M
D
E
V
A
I
H
T
P
T
Q
V
A
E
L
N
N
G
E
I
E
S
Y
Q
L
S
P
Q
D
F
G
L
Q
S
Y
S
L
N
A
L
Q
G
G
T
P
E
E
N
R
-
D
I
L
A
R
L
L
Q
G
-
K
G
D
A
A
H
A
R
Q
V
A
A
N
V
A
L
L
L
K
L
F
G
Q
-
D
--
N
-------
L
R
H
N
A
Q
L
A
L
E
T
I
R
S
G
T
A
F
E
R
V
T
A
L
A
A
R
-------
70
PsiBlast_CBE
93.57
36%
-91
- C13 -
3QQS
4
TRPD_MYCTU
B:
[29-369]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
RAE
W
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
---
18
PsiBlast_PDB
93.57
36%
-92
- C13 -
4OWO
7
TRPD_MYCTU
A:
[30-370]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
RAE
W
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
---
49
PsiBlast_CBE
93.54
36%
-92
- C13 -
4M0R
4
TRPD_MYCTO
A:
[31-370]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
---
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
RAE
W
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
----
37
PsiBlast_CBE
93.50
36%
-96
- C13 -
4N8Q
1
TRPD_MYCTU
B:
[30-372]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
----
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
RAE
W
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
L
A
-
62
PsiBlast_CBE
93.39
36%
-89
- C13 -
3QSA
4
TRPD_MYCTU
A:
[29-369]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
RAE
W
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
---
46
PsiBlast_CBE
93.21
36%
-92
- C13 -
4OWN
9
TRPD_MYCTU
B:
[30-371]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
-
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
RAE
W
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
L
--
20
PsiBlast_PDB
93.15
36%
-98
- C13 -
4OWS
2
TRPD_MYCTU
A:
[30-370]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPD
D
A
V
D
V
V
G
T
G
---
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
---
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
RAE
W
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
---
45
PsiBlast_CBE
93.12
36%
-91
- C13 -
4OWO
7
TRPD_MYCTU
B:
[30-371]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
RAE
W
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
L
--
50
PsiBlast_CBE
93.07
36%
-90
- C13 -
4GKM
10
TRPD_MYCTU
B:
[31-371]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
RAEWLPA
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
---
58
PsiBlast_CBE
93.04
36%
-91
- C13 -
3R88
3
TRPD_MYCTU
A:
[29-369]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
---AE
W
L
P
A
-
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
---
44
PsiBlast_CBE
93.03
36%
-91
- C13 -
4OWU
7
TRPD_MYCTU
A:
[30-370]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
RAE
W
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
---
39
PsiBlast_CBE
92.95
41%
-97
- C13 -
2ELC
2
TRPD_THET8
D:
[25-328]
--------------------------
L
M
A
G
E
V
S
P
V
R
A
A
G
L
L
V
A
L
S
L
R
G
E
R
P
H
E
I
A
A
M
A
R
A
M
R
E
A
A
R
P
L
R
V
H
--
R
R
P
----
L
L
D
I
V
G
T
G
G
D
G
K
G
L
M
N
L
S
T
L
A
A
L
V
A
A
A
G
G
V
A
V
A
K
H
G
N
R
A
A
S
S
R
A
G
S
A
D
L
L
E
A
L
G
V
D
L
E
A
P
P
E
R
V
G
E
A
I
E
E
L
G
F
G
F
L
F
A
R
V
F
H
P
A
M
R
H
V
A
P
V
R
A
E
L
G
V
R
T
V
F
N
L
L
G
P
L
T
N
P
A
G
A
D
A
Y
V
L
G
V
F
S
P
E
W
L
A
P
M
A
E
A
L
E
R
L
G
-
A
R
G
L
V
V
H
G
E
G
-
A
D
E
L
V
L
-
G
E
N
R
V
V
E
V
G
K
G
A
---
Y
A
L
T
P
E
E
V
G
L
K
R
A
P
L
E
A
L
K
G
G
G
P
E
E
N
A
-
A
L
A
R
R
L
L
K
G
E
E
-
K
G
P
L
A
D
A
V
A
L
A
A
G
A
G
F
Y
A
A
G
K
T
P
--
S
-------
L
K
E
G
V
A
L
A
R
E
V
L
A
S
G
E
A
Y
L
L
L
E
R
Y
V
A
F
L
R
-----
17
PsiBlast_PDB
92.92
36%
-90
- C13 -
4OWM
5
TRPD_MYCTU
A:
[30-370]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
RAE
W
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
---
38
PsiBlast_CBE
92.91
36%
-92
- C13 -
4N5V
6
TRPD_MYCTU
B:
[30-372]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
AEWLPA-
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
L
A
-
36
PsiBlast_CBE
92.86
36%
-91
- C13 -
4N93
5
TRPD_MYCTU
B:
[30-370]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
AEWLPA-
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
---
13
PsiBlast_PDB
92.81
36%
-89
- C13 -
4N93
6
TRPD_MYCTU
A:
[30-370]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
AE
W
L
P
A
-
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
---
43
PsiBlast_CBE
92.78
36%
-89
- C13 -
4OWU
6
TRPD_MYCTU
B:
[30-371]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
RAEWLPA
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
L
--
11
PsiBlast_PDB
92.78
36%
-91
- C13 -
4N5V
7
TRPD_MYCTU
A:
[30-370]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
AE
W
L
P
A
-
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
---
71
PsiBlast_CBE
92.71
36%
-90
- C13 -
3QQS
4
TRPD_MYCTU
A:
[29-369]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
RAE
W
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
---
57
PsiBlast_CBE
92.69
36%
-92
- C13 -
3R88
4
TRPD_MYCTU
B:
[29-369]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
---AEWLPA-
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
---
15
PsiBlast_PDB
92.21
41%
-95
- C13 -
2ELC
4
TRPD_THET8
A:
[25-328]
--------------------------
L
M
A
G
E
V
S
P
V
R
A
A
G
L
L
V
A
L
S
L
R
G
E
R
P
H
E
I
A
A
M
A
R
A
M
R
E
A
A
R
P
L
R
V
H
--
R
R
P
----
L
L
D
I
V
G
T
G
G
D
G
K
G
L
M
N
L
S
T
L
A
A
L
V
A
A
A
G
G
V
A
V
A
K
H
G
N
R
A
A
S
S
R
A
G
S
A
D
L
L
E
A
L
G
V
D
L
E
A
P
P
E
R
V
G
E
A
I
E
E
L
G
F
G
F
L
F
A
R
V
F
H
P
A
M
R
H
V
A
P
V
R
A
E
L
G
V
R
T
V
F
N
L
L
G
P
L
T
N
P
A
G
A
D
A
Y
V
L
G
V
F
S
P
E
W
L
A
P
M
A
E
A
L
E
R
L
G
-
A
R
G
L
V
V
H
G
E
G
-
A
D
E
L
V
L
-
G
E
N
R
V
V
E
V
G
K
G
A
---
Y
A
L
T
P
E
E
V
G
L
K
R
A
P
L
E
A
L
K
G
G
G
P
E
E
N
A
-
A
L
A
R
R
L
L
K
G
E
E
-
K
G
P
L
A
D
A
V
A
L
A
A
G
A
G
F
Y
A
A
G
K
T
P
--
S
-------
L
K
E
G
V
A
L
A
R
E
V
L
A
S
G
E
A
Y
L
L
L
E
R
Y
V
A
F
L
R
-----
51
PsiBlast_CBE
92.08
36%
-90
- C13 -
4GKM
8
TRPD_MYCTU
A:
[31-371]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
--
L
P
--
A
D
T
VPDD
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
-
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
-
A
A
V
R
A
V
L
G
G
-
A
-
R
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
--
S
RAEW
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
I
---
34
PsiBlast_CBE
91.18
35%
-91
- C13 -
3GBR
7
TRPD_SULSO
B:
[6-333]
----
I
L
K
K
L
I
N
K
S
D
L
E
I
N
E
A
E
E
L
A
K
A
I
I
R
G
E
V
P
E
I
L
V
S
A
I
L
V
A
L
R
M
K
G
E
S
K
N
E
I
V
G
F
A
R
A
M
R
E
L
A
I
K
I
D
V
P
----
N
----
A
I
D
T
A
G
T
G
G
G
G
L
G
T
V
N
V
S
T
A
S
A
I
L
L
S
L
V
N
-
P
V
A
K
H
G
N
R
A
V
S
G
K
S
G
S
A
D
V
L
E
A
L
G
Y
N
I
I
V
P
P
E
R
A
K
E
L
V
N
K
T
N
F
V
F
L
S
A
Q
Y
Y
H
P
A
M
K
N
V
A
N
V
R
K
T
L
G
I
R
T
I
F
N
I
L
G
P
L
T
N
P
A
N
A
K
Y
Q
L
M
G
V
F
S
K
D
H
L
D
L
L
S
K
S
A
Y
E
L
D
F
N
K
I
I
L
V
Y
G
E
P
G
I
D
E
V
S
P
I
G
N
T
F
M
K
I
V
S
K
R
G
I
E
E
V
K
L
N
V
T
D
F
G
I
S
P
I
P
I
E
K
L
I
V
N
S
A
E
D
S
A
I
K
I
V
R
A
F
L
-
G
-
K
-
D
E
H
V
A
E
F
I
K
I
N
T
A
V
A
L
F
A
L
D
R
V
G
--
D
-------
F
R
E
G
Y
E
Y
A
D
H
L
I
E
K
S
L
--
D
K
L
N
E
I
I
S
M
N
G
D
V
---
40
PsiBlast_CBE
90.86
41%
-96
- C13 -
2ELC
3
TRPD_THET8
C:
[25-328]
--------------------------
L
M
A
G
E
V
S
P
V
R
A
A
G
L
L
V
A
L
S
L
R
G
E
R
P
H
E
I
A
A
M
A
R
A
M
R
E
A
A
R
P
L
R
V
H
--
R
R
P
----
L
L
D
I
V
G
T
G
G
D
G
K
G
L
M
N
L
S
T
L
A
A
L
V
A
A
A
G
G
V
A
V
A
K
H
G
N
R
A
A
S
S
R
A
G
S
A
D
L
L
E
A
L
G
V
D
L
E
A
P
P
E
R
V
G
E
A
I
E
E
L
G
F
G
F
L
F
A
R
V
F
H
P
A
M
R
H
V
A
P
V
R
A
E
L
G
V
R
T
V
F
N
L
L
G
P
L
T
N
P
A
G
A
D
A
Y
V
L
G
V
F
S
P
E
W
L
A
P
M
A
E
A
L
E
R
L
G
-
A
R
G
L
V
V
H
G
E
G
-
A
D
E
L
V
L
-
G
E
N
R
V
V
E
V
G
K
G
A
---
Y
A
L
T
P
E
E
V
G
L
K
R
A
P
L
E
A
L
K
G
G
G
P
E
E
N
A
-
A
L
A
R
R
L
L
K
G
E
E
-
K
G
P
L
A
D
A
V
A
L
A
A
G
A
G
F
Y
A
A
G
K
T
P
--
S
-------
L
K
E
G
V
A
L
A
R
E
V
L
A
S
G
E
A
Y
L
L
L
E
R
Y
V
A
F
L
R
-----