@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1747: (2016-03-28 )
METVLKAHKVRKVYGSKGNLFSALGSISLEIQKGSFVGIMGPSGAGKSTLLNVLSSIDKPTSGEIEIGGKQISTMNGKELAVFRRDQLGFIFQDYNLLDTMTVKDNIVLPLALAHIKQAEIDQRFEIIARQFGIFELRNKYPTEISGGQKQRTAVCRAMITEPTLIFADEPTGALDSKSATNLLEGLSQAKDVRDSTIMMVTHDAFAASYCERIMFIKDGEIFTEIYRGTSSRKQFFQKVLDVLALLGGGENDVI
Atome Classification :
(39 SA)
.........10........20........30........40........50........60........70.......--.80........90------.........100......-.-110---------------.....---...120.......130....-...140...-------....150.......160.......170.......180.......190....--...200..-....-.210........220-.-----..------....--230.-......240---------........250...----------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
E
T
V
L
K
A
H
K
V
R
K
V
YGSKG
N
L
F
S
ALG
S
I
S
L
E
I
QKG
S
F
V
G
I
MGPSGA
G
K
S
T
L
L
N
V
L
S
SIDKPTSG
E
I
E
IG
G
K
Q
I
STMNGK--
E
L
A
V
F
RRDQL
G
F
-------
I
F
Q
DYNL
L
D
T
M
TVKD
N
I
V
-
L
-
P
L
----------------
A
L
A
H
I
---
K
Q
A
E
I
D
Q
R
F
E
I
I
A
R
QF
G
I
F
E
-
L
RNKYPTEI-------SGG
Q
K
Q
R
T
A
V
C
R
A
MITE
P
T
L
I
F
ADEPTGALDS
K
S
A
T
N
L
L
E
G
L
S
Q
A
KDVRD
S
--
T
I
M
M
V
T
H
D
-
A
F
A
A
-
S
Y
-
C
E
R
I
M
F
IKD
G
E
I
-
F
-----
T
E
------
I
Y
RG--T
S
S
R
-
K
Q
F
F
Q
K
V
L
----------
D
V
L
A
L
LGGGENDVI----------------------------------------------------------------------
11
PsiBlast_PDB
86.74
34%
-108
- C1 -
4YMS
-
?
J:
[4-240]
---------
V
N
D
V
Y
K
N
F
G
S
L
-
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
N
--
N
G
K
--
V
N
I
N
K
V
R
Q
K
V
G
M
-------
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
-
L
A
P
V
----------------
K
V
K
K
M
---
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-
K
K
D
Q
Y
P
I
K
L
-------
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
-
E
V
-
G
D
R
V
I
F
M
D
D
G
V
I
-
V
-----
E
E
GTPEEI
F
Y
R
A
--
K
N
E
R
T
R
E
F
L
S
K
I
L
----------------------------------------------------------------------------------------------
14
PsiBlast_PDB
86.28
34%
-105
- C1 -
4YMV
1
?
J:
[4-240]
---------
V
N
D
V
Y
K
N
F
G
S
L
-
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
N
--
N
G
K
--
V
N
I
N
K
V
R
Q
K
V
G
M
-------
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
-
L
A
P
V
----------------
K
V
K
K
M
---
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-
K
K
D
Q
Y
P
I
K
L
-------
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
-
E
V
-
G
D
R
V
I
F
M
D
D
G
V
I
-
V
-----
E
E
GTPEEI
F
Y
R
A
--
K
N
E
R
T
R
E
F
L
S
K
I
L
----------------------------------------------------------------------------------------------
31
PsiBlast_CBE
86.26
34%
-106
- C1 -
4YMV
1
?
A:
[4-240]
---------
V
N
D
V
Y
K
N
F
G
S
L
-
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
N
--
N
G
K
--
V
N
I
N
K
V
R
Q
K
V
G
M
-------
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
-
L
A
P
V
----------------
K
V
K
K
M
---
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-
K
K
D
Q
Y
P
I
K
L
-------
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
-
E
V
-
G
D
R
V
I
F
M
D
D
G
V
I
-
V
-----
E
E
GT
P
E
E
I
F
Y
R
A
--
K
N
E
R
T
R
E
F
L
S
K
I
L
----------------------------------------------------------------------------------------------
32
PsiBlast_CBE
86.17
34%
-108
- C1 -
4YMU
2
?
A:
[4-240]
---------
V
N
D
V
Y
K
N
F
G
S
L
-
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
N
--
N
G
K
--
V
N
I
N
K
V
R
Q
K
V
G
M
-------
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
-
L
A
P
V
----------------
K
V
K
K
M
---
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-
K
K
D
Q
Y
P
I
K
L
-------
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
-
E
V
-
G
D
R
V
I
F
M
D
D
G
V
I
-
V
-----
E
E
GT
P
E
E
I
F
Y
R
A
--
K
N
E
R
T
R
E
F
L
S
K
I
L
----------------------------------------------------------------------------------------------
12
PsiBlast_PDB
85.62
34%
-108
- C1 -
4YMT
-
?
J:
[4-240]
---------
V
N
D
V
Y
K
N
F
G
S
L
-
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
N
--
N
G
K
--
V
N
I
N
K
V
R
Q
K
V
G
M
-------
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
-
L
A
P
V
----------------
K
V
K
K
M
---
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-
K
K
D
Q
Y
P
I
K
L
-------
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
-
E
V
-
G
D
R
V
I
F
M
D
D
G
V
I
-
V
-----
E
E
GTPEEI
F
Y
R
A
--
K
N
E
R
T
R
E
F
L
S
K
I
L
----------------------------------------------------------------------------------------------
13
PsiBlast_PDB
85.59
34%
-107
- C1 -
4YMU
2
?
J:
[4-240]
---------
V
N
D
V
Y
K
N
F
G
S
L
-
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
N
--
N
G
K
--
V
N
I
N
K
V
R
Q
K
V
G
M
-------
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
-
L
A
P
V
----------------
K
V
K
K
M
---
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-
K
K
D
Q
Y
P
I
K
L
-------
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
-
E
V
-
G
D
R
V
I
F
M
D
D
G
V
I
-
V
-----
E
E
GTPEEI
F
Y
R
A
--
K
N
E
R
T
R
E
F
L
S
K
I
L
----------------------------------------------------------------------------------------------
15
PsiBlast_PDB
84.80
34%
-105
- C1 -
4YMW
-
?
J:
[4-240]
---------
V
N
D
V
Y
K
N
F
G
S
L
-
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
N
--
N
G
K
--
V
N
I
N
K
V
R
Q
K
V
G
M
-------
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
-
L
A
P
V
----------------
K
V
K
K
M
---
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-
K
K
D
Q
Y
P
I
K
L
-------
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
-
E
V
-
G
D
R
V
I
F
M
D
D
G
V
I
-
V
-----
E
E
GTPEEI
F
Y
R
A
--
K
N
E
R
T
R
E
F
L
S
K
I
L
----------------------------------------------------------------------------------------------
35
PsiBlast_CBE
84.27
31%
-112
- C1 -
4U02
1
?
C:
[1-242]
M
E
P
I
I
R
I
R
N
L
H
K
W
F
G
P
----
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
--
L
S
V
K
D
D
R
--
A
L
R
E
I
R
R
E
-
V
G
M
-------
V
F
Q
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
-
L
A
P
M
----------------
R
V
R
R
W
---
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
L
D
-
Q
A
R
K
Y
P
A
Q
L
-------
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
---
R
D
L
A
Q
G
GM
T
M
V
V
V
T
H
E
M
G
F
A
R
-
E
V
-
A
D
R
V
V
F
M
D
G
G
Q
I
-
V
-----
E
E
GRPEEI
F
T
R
P
--
K
E
E
R
T
R
S
F
L
Q
R
V
L
----------------------------------------------------------------------------------------------
22
PsiBlast_CBE
83.83
37%
-101
- C1 -
3TIF
7
Y796_METJA
B:
[1-232]
---
M
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
N
D
L
D
D
D
--
E
L
T
K
I
R
R
D
K
I
G
F
-------
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
-
L
-
P
L
IFKYRGAMSGEERRKR
A
L
E
C
L
---
K
M
A
E
L
E
E
R
F
A
-------------
N
H
K
P
N
Q
L
-------
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
--
T
V
V
V
V
T
H
D
-
I
N
V
A
-
R
F
-
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
-----
E
E
------
K
L
R
G
--
F
----------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
83.63
38%
-99
- C1 -
1L2T
4
Y796_METJA
A:
[1-230]
---
M
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
N
D
L
D
D
D
--
E
L
T
K
I
R
R
D
K
I
G
F
-------
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
-
L
-
P
L
IFKYR
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
---
K
M
A
E
L
E
E
R
F
A
-------------
N
H
K
P
N
Q
L
-------
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
--
T
V
V
V
V
T
H
D
-
I
N
V
A
-
R
F
-
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
-----
E
E
------
K
L
R
--------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
83.49
38%
-99
- C1 -
1L2T
4
Y796_METJA
B:
[1-232]
---
M
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
N
D
L
D
D
D
--
E
L
T
K
I
R
R
D
K
I
G
F
-------
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
-
L
-
P
L
IFKYRGAMSGEERRKR
A
L
E
C
L
---
K
M
A
E
L
E
E
R
F
A
-------------
N
H
K
P
N
Q
L
-------
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
--
T
V
V
V
V
T
H
D
-
I
N
V
A
-
R
F
-
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
-----
E
E
------
K
L
R
G
--
F
----------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
83.27
36%
-104
- C1 -
2PCJ
1
LOLD_AQUAE
B:
[2-223]
-
A
E
I
L
R
A
E
N
I
K
K
V
I
R
G
----
Y
E
I
L
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
F
L
E
G
K
E
V
D
Y
T
N
E
K
--
E
L
S
L
L
R
N
R
K
L
G
F
-------
V
F
Q
F
H
Y
L
I
P
E
L
T
A
L
E
N
V
I
-
V
-
P
M
----------------
L
K
M
G
K
---
P
K
K
E
A
K
E
R
G
E
Y
L
L
S
E
L
G
L
G
D
-
K
L
S
R
K
P
Y
E
L
-------
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
I
N
E
-
G
G
T
--
S
I
V
M
V
T
H
E
-
R
E
L
A
-
E
L
-
T
H
R
T
L
E
M
K
D
G
K
V
-
V
-----
G
E
------
I
T
R
--------------------------------------------------------------------------------------------------------------
36
PsiBlast_CBE
83.07
31%
-105
- C1 -
4U02
1
?
B:
[1-242]
M
E
P
I
I
R
I
R
N
L
H
K
W
F
G
P
----
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
--
L
S
V
K
D
D
R
--
A
L
R
E
I
R
R
E
-
V
G
M
-------
V
F
Q
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
-
L
A
P
M
----------------
R
V
R
R
W
---
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
L
D
-
Q
A
R
K
Y
P
A
Q
L
-------
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
---
R
D
L
A
Q
G
GM
T
M
V
V
V
T
H
E
M
G
F
A
R
-
E
V
-
A
D
R
V
V
F
M
D
G
G
Q
I
-
V
-----
E
E
GRPEEI
F
T
R
P
--
K
E
E
R
T
R
S
F
L
Q
R
V
L
----------------------------------------------------------------------------------------------
120
HHSearch
82.90
38%
-102
- C1 -
3TIF
7
Y796_METJA
A:
[1-230]
---
M
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
N
D
L
D
D
D
--
E
L
T
K
I
R
R
D
K
I
G
F
-------
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
-
L
-
P
L
----------------
I
F
K
Y
R
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
F
A
N
H
K
P
N
Q
L
-------
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
--
T
V
V
V
V
T
H
D
-
I
N
V
A
-
R
F
-
G
E
R
I
I
Y
L
K
D
G
E
V
-
E
-----
R
E
------
E
K
L
R
-------------------------------------------------------------------------------------------------------------
117
HHSearch
82.67
37%
-98
- C1 -
2PCJ
-
LOLD_AQUAE
A:
[2-222]
-
A
E
I
L
R
A
E
N
I
K
K
V
I
R
G
----
Y
E
I
L
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
F
L
E
G
K
E
V
D
Y
T
N
E
K
--
E
L
S
L
L
R
N
R
K
L
G
F
-------
V
F
Q
F
H
Y
L
I
P
E
L
T
A
L
E
N
V
I
-
V
-
P
M
----------------
L
K
M
G
K
---
P
K
K
E
A
K
E
R
G
E
Y
L
L
S
E
L
G
L
G
D
-
K
L
S
R
K
P
Y
E
L
-------
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
I
N
E
-
G
G
T
--
S
I
V
M
V
T
H
E
-
R
E
L
A
-
E
L
-
T
H
R
T
L
E
M
K
D
G
K
V
-
V
-----
G
E
------
I
T
---------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
82.35
36%
-98
- C1 -
2PCJ
-
LOLD_AQUAE
A:
[2-223]
-
A
E
I
L
R
A
E
N
I
K
K
V
I
R
G
----
Y
E
I
L
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
F
L
E
G
K
E
V
D
Y
T
N
E
K
--
E
L
S
L
L
R
N
R
K
L
G
F
-------
V
F
Q
F
H
Y
L
I
P
E
L
T
A
L
E
N
V
I
-
V
-
P
M
----------------
L
K
M
G
K
---
P
K
K
E
A
K
E
R
G
E
Y
L
L
S
E
L
G
L
G
D
-
K
L
S
R
K
P
Y
E
L
-------
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
I
N
E
-
G
G
T
--
S
I
V
M
V
T
H
E
-
R
E
L
A
-
E
L
-
T
H
R
T
L
E
M
K
D
G
K
V
-
V
-----
G
E
------
I
T
R
--------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
82.30
31%
-110
- C1 -
4U00
3
?
A:
[3-242]
--
P
I
I
R
I
R
N
L
H
K
W
F
G
P
----
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
--
L
S
V
K
D
D
R
--
A
L
R
E
I
R
R
E
-
V
G
M
-------
V
F
Q
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
-
L
A
P
M
----------------
R
V
R
R
W
---
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
L
D
-
Q
A
R
K
Y
P
A
Q
L
-------
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
---
R
D
L
A
Q
G
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
-
E
V
-
A
D
R
V
V
F
M
D
G
G
Q
I
-
V
-----
E
E
GR
P
E
E
I
F
T
R
P
--
K
E
E
R
T
R
S
F
L
Q
R
V
L
----------------------------------------------------------------------------------------------
37
PsiBlast_CBE
82.18
31%
-105
- C1 -
4U02
1
?
A:
[1-242]
M
E
P
I
I
R
I
R
N
L
H
K
W
F
G
P
----
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
--
L
S
V
K
D
D
R
--
A
L
R
E
I
R
R
E
-
V
G
M
-------
V
F
Q
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
-
L
A
P
M
----------------
R
V
R
R
W
---
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
L
D
-
Q
A
R
K
Y
P
A
Q
L
-------
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
---
R
D
L
A
Q
G
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
-
E
V
-
A
D
R
V
V
F
M
D
G
G
Q
I
-
V
-----
E
E
GR
P
E
E
I
F
T
R
P
--
K
E
E
R
T
R
S
F
L
Q
R
V
L
----------------------------------------------------------------------------------------------
5
PsiBlast_PDB
81.85
36%
-96
- C1 -
2PCL
12
LOLD_AQUAE
A:
[2-223]
-
A
E
I
L
R
A
E
N
I
K
K
V
I
R
G
----
Y
E
I
L
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
F
L
E
G
K
E
V
D
Y
T
N
E
K
--
E
L
S
L
L
R
N
R
K
L
G
F
-------
V
F
Q
F
H
Y
L
I
P
E
L
T
A
L
E
N
V
I
-
V
-
P
M
----------------
L
K
M
G
K
---
P
K
K
E
A
K
E
R
G
E
Y
L
L
S
E
L
G
L
G
D
-
K
L
S
R
K
P
Y
E
L
-------
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
I
N
E
-
G
G
T
--
S
I
V
M
V
T
H
E
-
R
E
L
A
-
E
L
-
T
H
R
T
L
E
M
K
D
G
K
V
-
V
-----
G
E
------
I
T
R
--------------------------------------------------------------------------------------------------------------
124
Fugue
81.76
31%
-110
- C1 -
3TUZ
3
METN_ECOLI
H:
[23-362]
--
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
--
E
L
T
K
A
R
R
Q
-
I
G
M
-------
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
A
-
L
-
P
L
----------------
E
L
D
N
T
---
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
-
K
H
D
S
Y
P
S
N
L
-------
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
--
T
I
L
L
I
T
H
E
-
M
D
V
V
-
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
-
I
EQDTV
S
E
------
V
F
S
H
PK
T
P
L
A
-
Q
K
F
I
Q
S
T
L
HLDIPEDYQE
R
L
Q
A
E
P
F
T
D
C
V
P
M
L
RLEFTGQSVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHHVKVEV
90
PsiBlast_CBE
76.30
36%
-100
- C1 -
3FVQ
3
FBPC_NEIG1
B:
[20-244]
-----------------------
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
K
T
I
F
S
K
N
-
T
--
N
L
P
V
-
R
E
R
R
L
G
Y
-------
L
V
Q
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
A
-
Y
-
G
L
----------------
G
N
G
K
G
---
R
T
A
Q
E
R
Q
R
I
E
A
M
L
E
L
T
G
I
S
E
-
L
A
G
R
Y
P
H
E
L
-------
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
G
K
--
S
A
V
F
V
S
H
D
-
R
E
E
A
L
Q
Y
-
A
D
R
I
A
V
M
K
Q
G
R
I
-
L
-----
Q
-------------
T
A
S
P
-
H
E
L
Y
R
Q
P
A
----------
D
L
D
A
A
L
F
I
G
E
G
I
V
-----------------------------------------------------------------------
91
PsiBlast_CBE
75.94
36%
-99
- C1 -
3FVQ
3
FBPC_NEIG1
A:
[20-249]
-----------------------
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
K
T
I
F
S
K
N
-
T
--
N
L
P
V
-
R
E
R
R
L
G
Y
-------
L
V
Q
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
A
-
Y
-
G
L
----------------
G
N
G
K
G
---
R
T
A
Q
E
R
Q
R
I
E
A
M
L
E
L
T
G
I
S
E
-
L
A
G
R
Y
P
H
E
L
-------
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
G
K
--
S
A
V
F
V
S
H
D
-
R
E
E
A
L
Q
Y
-
A
D
R
I
A
V
M
K
Q
G
R
I
-
L
-----
Q
-------------
T
A
S
P
-
H
E
L
Y
R
Q
P
A
----------
D
L
D
A
A
L
F
I
G
E
G
I
V
-----------------------------------------------------------------------
60
PsiBlast_CBE
73.79
32%
-103
- C1 -
2OLJ
4
?
A:
[22-240]
-
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
K
D
T
N
--
L
N
K
V
--
R
E
E
V
G
M
-------
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
-
L
A
P
M
----------------
K
V
R
K
W
---
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
L
-------
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
-
E
V
-
G
D
R
V
L
F
M
D
G
G
Y
I
-
I
-----
E
E
-----------------------------------------------------------------------------------------------------------------------
55
PsiBlast_CBE
72.74
32%
-94
- C1 -
2OLK
1
?
D:
[22-240]
-
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
K
D
T
N
--
L
N
K
V
--
R
E
E
V
G
M
-------
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
-
L
A
P
M
----------------
K
V
R
K
W
---
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
L
-------
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
-
E
V
-
G
D
R
V
L
F
M
D
G
G
Y
I
-
I
-----
E
E
-----------------------------------------------------------------------------------------------------------------------
56
PsiBlast_CBE
72.30
32%
-95
- C1 -
2OLK
1
?
C:
[22-240]
-
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
K
D
T
N
--
L
N
K
V
--
R
E
E
V
G
M
-------
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
-
L
A
P
M
----------------
K
V
R
K
W
---
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
L
-------
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
-
E
V
-
G
D
R
V
L
F
M
D
G
G
Y
I
-
I
-----
E
E
-----------------------------------------------------------------------------------------------------------------------
96
PsiBlast_CBE
71.85
31%
-102
- C1 -
1B0U
4
HISP_SALTY
A:
[5-234]
--
N
K
L
H
V
I
D
L
H
K
R
Y
G
G
----
H
E
V
L
K
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
I
I
V
N
G
Q
N
I
N
L
V
R
D
K
DG
Q
L
K
V
A
D
K
N
Q
L
R
L
L
R
T
R
L
T
M
V
F
Q
H
F
N
L
W
S
H
M
T
V
L
E
N
V
M
E
A
-
P
I
----------------
Q
V
L
G
L
---
S
K
H
D
A
R
E
R
A
L
K
Y
L
A
K
V
G
I
D
E
R
A
Q
G
K
Y
P
V
H
L
-------
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
R
I
M
Q
Q
L
A
E
-
E
G
K
--
T
M
V
V
V
T
H
E
M
G
F
A
R
-
H
V
-
S
S
H
V
I
F
L
H
Q
G
K
I
-
E
-----
E
E
-----------------------------------------------------------------------------------------------------------------------
58
PsiBlast_CBE
71.47
32%
-93
- C1 -
2OLK
1
?
A:
[22-240]
-
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
K
D
T
N
--
L
N
K
V
--
R
E
E
V
G
M
-------
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
-
L
A
P
M
----------------
K
V
R
K
W
---
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
L
-------
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
-
E
V
-
G
D
R
V
L
F
M
D
G
G
Y
I
-
I
-----
E
E
-----------------------------------------------------------------------------------------------------------------------
47
PsiBlast_CBE
71.06
32%
-100
- C1 -
3C4J
4
?
B:
[22-240]
-
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
K
D
T
N
--
L
N
K
V
--
R
E
E
V
G
M
-------
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
-
L
A
P
M
----------------
K
V
R
K
W
---
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
L
-------
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
-
E
V
-
G
D
R
V
L
F
M
D
G
G
Y
I
-
I
-----
E
E
-----------------------------------------------------------------------------------------------------------------------
50
PsiBlast_CBE
70.83
32%
-96
- C1 -
2Q0H
4
?
A:
[23-240]
--
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
K
D
T
N
--
L
N
K
V
--
R
E
E
V
G
M
-------
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
-
L
A
P
M
----------------
K
V
R
K
W
---
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
L
-------
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
-
E
V
-
G
D
R
V
L
F
M
D
G
G
Y
I
-
I
-----
E
E
-----------------------------------------------------------------------------------------------------------------------
61
PsiBlast_CBE
70.70
32%
-99
- C1 -
3C41
3
?
K:
[3-219]
---
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
K
D
T
N
--
L
N
K
V
--
R
E
E
V
G
M
-------
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
-
L
A
P
M
----------------
K
V
R
K
W
---
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
L
-------
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
-
E
V
-
G
D
R
V
L
F
M
D
G
G
Y
I
-
I
-----
E
E
-----------------------------------------------------------------------------------------------------------------------
62
PsiBlast_CBE
70.68
32%
-99
- C1 -
3C41
3
?
J:
[3-219]
---
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
K
D
T
N
--
L
N
K
V
--
R
E
E
V
G
M
-------
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
-
L
A
P
M
----------------
K
V
R
K
W
---
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
L
-------
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
-
E
V
-
G
D
R
V
L
F
M
D
G
G
Y
I
-
I
-----
E
E
-----------------------------------------------------------------------------------------------------------------------
48
PsiBlast_CBE
70.19
32%
-93
- C1 -
3C4J
3
?
A:
[22-240]
-
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
K
D
T
N
--
L
N
K
V
--
R
E
E
V
G
M
-------
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
-
L
A
P
M
----------------
K
V
R
K
W
---
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
L
-------
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
-
E
V
-
G
D
R
V
L
F
M
D
G
G
Y
I
-
I
-----
E
E
-----------------------------------------------------------------------------------------------------------------------
57
PsiBlast_CBE
69.82
32%
-93
- C1 -
2OLK
2
?
B:
[22-240]
-
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
K
D
T
N
--
L
N
K
V
--
R
E
E
V
G
M
-------
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
-
L
A
P
M
----------------
K
V
R
K
W
---
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
L
-------
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
-
E
V
-
G
D
R
V
L
F
M
D
G
G
Y
I
-
I
-----
E
E
-----------------------------------------------------------------------------------------------------------------------
59
PsiBlast_CBE
68.88
32%
-90
- C1 -
2OLJ
3
?
B:
[22-240]
-
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
K
D
T
N
--
L
N
K
V
--
R
E
E
V
G
M
-------
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
-
L
A
P
M
----------------
K
V
R
K
W
---
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
L
-------
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
-
E
V
-
G
D
R
V
L
F
M
D
G
G
Y
I
-
I
-----
E
E
-----------------------------------------------------------------------------------------------------------------------
49
PsiBlast_CBE
68.04
32%
-93
- C1 -
2Q0H
4
?
B:
[22-240]
-
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
K
D
T
N
--
L
N
K
V
--
R
E
E
V
G
M
-------
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
-
L
A
P
M
----------------
K
V
R
K
W
---
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
P
D
S
L
-------
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
-
E
V
-
G
D
R
V
L
F
M
D
G
G
Y
I
-
I
-----
E
E
-----------------------------------------------------------------------------------------------------------------------
100
PsiBlast_CBE
56.41
33%
-92
- C1 -
2HYD
3
Y1866_STAAM
A:
[357-553]
-----------------------
L
K
D
I
N
L
S
I
E
K
G
E
T
V
A
F
V
G
M
S
G
G
G
K
S
T
L
I
N
L
I
P
R
F
Y
D
V
T
S
G
Q
I
L
I
D
G
H
N
I
K
D
F
L
T
G
--
S
L
----
R
N
Q
I
G
L
-------
V
Q
Q
D
-
N
I
L
F
S
D
T
V
K
E
N
I
L
-
L
-
G
R
----------------
P
T
A
-----
T
D
E
E
V
V
E
A
A
K
M
A
N
A
H
D
F
I
M
N
-
L
P
Q
G
Y
D
T
E
V
GERGVKL
S
G
G
Q
K
Q
R
L
S
I
A
R
I
F
L
N
N
P
P
I
L
I
L
D
E
A
T
S
A
L
D
L
E
S
E
S
I
I
Q
E
A
L
D
V
L
S
--
K
D
R
--
T
T
L
I
V
A
H
R
-
L
S
T
I
-
T
H
-
A
D
K
I
V
V
I
E
N
G
H
I
--------------------------------------------------------------------------------------------------------------------------------
99
PsiBlast_CBE
56.34
33%
-92
- C1 -
2HYD
3
Y1866_STAAM
B:
[357-553]
-----------------------
L
K
D
I
N
L
S
I
E
K
G
E
T
V
A
F
V
G
M
S
G
G
G
K
S
T
L
I
N
L
I
P
R
F
Y
D
V
T
S
G
Q
I
L
I
D
G
H
N
I
K
D
F
L
T
G
--
S
L
----
R
N
Q
I
G
L
-------
V
Q
Q
D
-
N
I
L
F
S
D
T
V
K
E
N
I
L
-
L
-
G
R
----------------
P
T
A
-----
T
D
E
E
V
V
E
A
A
K
M
A
N
A
H
D
F
I
M
N
-
L
P
Q
G
Y
D
T
E
V
GERGVKL
S
G
G
Q
K
Q
R
L
S
I
A
R
I
F
L
N
N
P
P
I
L
I
L
D
E
A
T
S
A
L
D
L
E
S
E
S
I
I
Q
E
A
L
D
V
L
S
--
K
D
R
--
T
T
L
I
V
A
H
R
-
L
S
T
I
-
T
H
-
A
D
K
I
V
V
I
E
N
G
H
I
--------------------------------------------------------------------------------------------------------------------------------
97
PsiBlast_CBE
55.72
33%
-90
- C1 -
2ONJ
4
Y1866_STAAM
B:
[357-553]
-----------------------
L
K
D
I
N
L
S
I
E
K
G
E
T
V
A
F
V
G
M
S
G
G
G
K
S
T
L
I
N
L
I
P
R
F
Y
D
V
T
S
G
Q
I
L
I
D
G
H
N
I
K
D
F
L
T
G
--
S
L
----
R
N
Q
I
G
L
-------
V
Q
Q
D
-
N
I
L
F
S
D
T
V
K
E
N
I
L
-
L
-
G
R
----------------
P
T
A
-----
T
D
E
E
V
V
E
A
A
K
M
A
N
A
H
D
F
I
M
N
-
L
P
Q
G
Y
D
T
E
V
GERGVKL
S
G
G
Q
K
Q
R
L
S
I
A
R
I
F
L
N
N
P
P
I
L
I
L
D
E
A
T
S
A
L
D
L
E
S
E
S
I
I
Q
E
A
L
D
V
L
S
--
K
D
R
--
T
T
L
I
V
A
H
R
-
L
S
T
I
-
T
H
-
A
D
K
I
V
V
I
E
N
G
H
I
--------------------------------------------------------------------------------------------------------------------------------
98
PsiBlast_CBE
55.53
33%
-91
- C1 -
2ONJ
4
Y1866_STAAM
A:
[357-553]
-----------------------
L
K
D
I
N
L
S
I
E
K
G
E
T
V
A
F
V
G
M
S
G
G
G
K
S
T
L
I
N
L
I
P
R
F
Y
D
V
T
S
G
Q
I
L
I
D
G
H
N
I
K
D
F
L
T
G
--
S
L
----
R
N
Q
I
G
L
-------
V
Q
Q
D
-
N
I
L
F
S
D
T
V
K
E
N
I
L
-
L
-
G
R
----------------
P
T
A
-----
T
D
E
E
V
V
E
A
A
K
M
A
N
A
H
D
F
I
M
N
-
L
P
Q
G
Y
D
T
E
V
GERGVKL
S
G
G
Q
K
Q
R
L
S
I
A
R
I
F
L
N
N
P
P
I
L
I
L
D
E
A
T
S
A
L
D
L
E
S
E
S
I
I
Q
E
A
L
D
V
L
S
--
K
D
R
--
T
T
L
I
V
A
H
R
-
L
S
T
I
-
T
H
-
A
D
K
I
V
V
I
E
N
G
H
I
--------------------------------------------------------------------------------------------------------------------------------