@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2489: (2016-04-04 )
LKDKFELVSKYSPQGDQPRAIEQLVAGLKKGLKHQTLLGATGTGKTFTVSNVIQEVNKPTLVMAHNKTLAGQLYSEFKEFFPNNAVEYFVSYYDYYQPEAYVPQSDTYIEKDASINDEIDKLRHSATAALFERRDVIIIASVSCIYGLGSPIEYGEMLVSLRVGMEISRDQLLRKLVDIQYDRNDIDFQRGRFRVRGDVVEIFPASRDEHCMRIEFFGDEIERIREVDALTGEIIGEREHVSIFPASHFVTRPDIMKKAIVNIKAELEDRLKVLRADNKLLEAQRLEQRTNYDLEMMEEMGYCSGIENYSRHLSLRPAGVTPYTLLDYFPDDFQMVIDESHVTMPQIRGMFNGDQARKQMLVDHGFRLPSALDNRPLRLEEFEKHINQIMFISATPGPYELEKNPDVIEQIIRPTGLLDPIVEIRPIQGQIDDLMDEINDRVEKNERVLITTLTKKMSEDLTNYLKEAGVKVQYLHSEVKTLERIEIIRDLRLGVYDVIVGINLLREGIDLPEVSLVAILDADKEGFLRSERSLIQTMGRAARNENGRVIMYADKMTDSMRNSIGETERRRKIQIEYNEKHGITPKTIKKEIRGIIAATSAADEREAVKQHDLSKMSKKERDVFIEGMEHEMKEAAKALDFERAAELRDALLEIKAEG
Atome Classification :
(20 SA)
-.........10........20........30........40.........50......-..--60........70........80........90........100.......110.......120.......130-.......140.-......150......-.160.......170.......180.......190.......200....-...210.......220...-....230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.-.....--.370.......380....--...390.--......400---.......410.......420..-.....430.......440.....-..450.......460.......470...--....480.......490.......500.......510......-------.520.......530.......540.-......550.......560.......570........580.......590.......600.......610......----.620.......630.......640.......650......--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-LK
D
K
F
E
L
V
S
KYSPQGDQ
P
R
A
I
E
Q
L
V
A
G
L
K
KGLKHQ
T
L
LGA-TGTG
K
T
F
T
V
S
N
V
I
Q
EVN-K
P
--
T
L
V
M
AHNK
T
L
A
G
Q
L
Y
S
E
F
K
E
FFPN
N
A
V
E
Y
F
V
S
Y
Y
D
Y
YQPEAYVPQSD
T
Y
IEKDASI
N
D
E
I
D
K
L
R
H
S
A
T
A
A
L
F
E-RR
D
V
I
I
I
A
S
V
S
-
C
I
YGLGS
P
I
E
Y
G
E
M
L
-
V
S
L
RVGMEI
S
R
D
Q
L
L
R
K
L
V
D
IQYDRNDIDFQR
G
R
F
R
V
RG
D
V
V
E
I
FPAS-RDE
H
C
M
R
I
E
FF
G
D
E
I
E
R
I
R
-
E
V
D
A
L
T
G
E
IIGER
E
H
V
S
I
FPASHFVT
R
P
D
I
M
K
K
A
I
V
N
I
K
A
E
L
E
D
R
L
K
V
L
RAD
N
K
L
L
E
A
Q
R
L
E
Q
RTNY
D
L
E
M
M
E
EMGYCS
G
I
E
N
Y
S
R
HLSLRPAGVT
P
Y
T
L
L
DYFPD
D
F
Q
M
V
IDESHV
T
M
P
Q
I
R
G
MFN
G
D
Q
A
R
K
Q
M
L
V
D-HGFRL--
P
S
ALDNRPL
R
L
E
E
F
E
K
H
I
--
N
Q
I
M
F
I
S--ATPGPYELE---K
N
P
D
V
I
E
Q
I
I
RPTGLLDPI
V
E
I-RPIQG
Q
I
D
D
L
M
D
E
I
N
D
R
VEKNE
R
-
V
L
I
T
T
L
T
K
K
M
S
E
D
L
T
N
Y
L
K
EAG
V
K
V
Q
Y
L
--
H
S
E
V
K
T
L
E
R
I
E
I
I
R
D
L
R
L
G
V
Y
D
V
I
V
G
I
N
L
L
R
EGIDLPE
V
S
L
V
A
-------
I
LDADKEG
F
L
R
S
E
R
S
L
I
Q
T
M
G
R
AAR-NENG
R
V
I
M
Y
A
D
K
M
T
D
S
M
R
N
SIG
E
T
E
R
R
R
-
K
I
Q
I
E
YNEKHGI
T
P
K
T
I
K
K
E
I
R
G
I
I
AATSAA
D
E
R
E
A
V
K
Q
H
D
L
S
K
M
S
K
----
K
E
R
D
V
F
I
E
G
M
E
H
E
M
K
E
A
A
K
AL
D
F
E
R
A
A
E
L
R
D
A
L
L
E
IKAEG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
HHSearch
91.32
80%
-94
- C3 -
2D7D
2
UVRB_BACSU
A:
[3-654]
---
D
R
F
E
L
V
S
K
Y
Q
P
Q
G
D
Q
P
K
A
I
E
K
L
V
K
G
I
Q
E
G
K
K
H
Q
T
L
L
G
A
-
T
G
T
G
K
T
F
T
V
S
N
L
I
K
E
V
N
-
K
P
--
T
L
V
I
A
H
N
K
T
L
A
G
Q
L
Y
S
E
F
K
E
F
F
P
N
N
A
V
E
Y
F
V
S
Y
Y
D
Y
Y
Q
P
E
A
Y
V
P
Q
T
D
T
F
I
E
K
D
A
S
I
N
D
E
I
D
K
L
R
H
S
A
T
S
A
L
F
E
-
R
R
D
V
I
I
I
A
S
V
S
-
C
I
Y
G
L
G
S
P
E
E
Y
R
E
M
V
-
V
S
L
R
T
E
M
E
I
E
R
N
E
L
L
R
K
L
V
D
I
Q
Y
A
R
N
D
I
D
F
Q
R
G
T
F
R
V
R
G
D
V
V
E
I
F
P
A
S
R
D
-
E
H
C
V
R
V
E
F
F
G
D
E
I
E
R
I
R
-
E
V
D
A
L
T
G
E
I
L
G
D
R
D
H
V
A
I
F
P
A
S
H
F
V
T
R
A
E
K
M
E
K
A
I
Q
N
I
E
K
E
L
E
E
Q
L
K
V
M
H
E
N
G
K
L
L
E
A
Q
R
L
E
Q
R
T
R
Y
D
L
E
M
M
R
E
M
G
F
C
S
G
I
E
N
Y
S
R
H
L
T
L
R
P
P
G
S
T
P
Y
T
L
L
D
Y
F
P
D
D
F
M
I
V
V
D
E
S
H
V
T
I
P
Q
V
R
G
M
F
N
G
D
Q
A
R
K
Q
V
L
V
D
-
H
G
F
R
L
--
P
S
A
L
D
N
R
P
L
R
F
E
E
F
E
K
H
M
--
H
N
I
V
Y
V
S
--
A
T
P
G
P
Y
E
I
E
---
H
T
D
E
M
V
E
Q
I
I
R
P
T
G
L
L
D
P
L
I
D
V
-
R
P
I
E
G
Q
I
D
D
L
I
G
E
I
Q
A
R
I
E
R
N
E
R
-
V
L
V
T
T
L
T
K
K
M
S
E
D
L
T
D
Y
L
K
E
I
G
I
K
V
N
Y
L
--
H
S
E
I
K
T
L
E
R
I
E
I
I
R
D
L
R
L
G
K
Y
D
V
L
V
G
I
N
L
L
R
E
G
L
D
I
P
E
V
S
L
V
A
-------
I
L
D
A
D
K
E
G
F
L
R
S
E
R
S
L
I
Q
T
I
G
R
A
A
R
-
N
A
E
G
R
V
I
M
Y
A
D
K
I
T
K
S
M
E
I
A
I
N
E
T
K
R
R
R
-
E
Q
Q
E
R
F
N
E
E
H
G
I
T
P
K
T
I
N
----------------------------
K
----
K
E
R
Q
K
V
V
E
Q
M
E
H
E
M
K
E
A
A
K
A
L
D
F
E
R
A
A
E
L
R
D
L
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
91.06
79%
-94
- C3 -
2D7D
2
UVRB_BACSU
A:
[3-654]
---
D
R
F
E
L
V
S
K
Y
Q
P
Q
G
D
Q
P
K
A
I
E
K
L
V
K
G
I
Q
E
G
K
K
H
Q
T
L
L
G
A
-
T
G
T
G
K
T
F
T
V
S
N
L
I
K
E
V
N
-
K
P
--
T
L
V
I
A
H
N
K
T
L
A
G
Q
L
Y
S
E
F
K
E
F
F
P
N
N
A
V
E
Y
F
V
S
Y
Y
D
Y
Y
Q
P
E
A
Y
V
P
Q
T
D
T
F
I
E
K
D
A
S
I
N
D
E
I
D
K
L
R
H
S
A
T
S
A
L
F
E
-
R
R
D
V
I
I
I
A
S
V
S
-
C
I
Y
G
L
G
S
P
E
E
Y
R
E
M
V
-
V
S
L
R
T
E
M
E
I
E
R
N
E
L
L
R
K
L
V
D
I
Q
Y
A
R
N
D
I
D
F
Q
R
G
T
F
R
V
R
G
D
V
V
E
I
F
P
A
S
-
R
D
E
H
C
V
R
V
E
F
F
G
D
E
I
E
R
I
R
-
E
V
D
A
L
T
G
E
I
L
G
D
R
D
H
V
A
I
F
P
A
S
H
F
V
T
R
A
E
K
M
E
K
A
I
Q
N
I
E
K
E
L
E
E
Q
L
K
V
M
H
E
N
G
K
L
L
E
A
Q
R
L
E
Q
R
T
R
Y
D
L
E
M
M
R
E
M
G
F
C
S
G
I
E
N
Y
S
R
H
L
T
L
R
P
P
G
S
T
P
Y
T
L
L
D
Y
F
P
D
D
F
M
I
V
V
D
E
S
H
V
T
I
P
Q
V
R
G
M
F
N
G
D
Q
A
R
K
Q
V
L
V
D
-
H
G
F
R
L
--
P
S
A
L
D
N
R
P
L
R
F
E
E
F
E
K
H
M
--
H
N
I
V
Y
V
S
--
A
T
P
G
P
Y
E
I
E
---
H
T
D
E
M
V
E
Q
I
I
R
P
T
G
L
L
D
P
L
I
D
V
-
R
P
I
E
G
Q
I
D
D
L
I
G
E
I
Q
A
R
I
E
R
N
E
R
-
V
L
V
T
T
L
T
K
K
M
S
E
D
L
T
D
Y
L
K
E
I
G
I
K
V
N
Y
L
--
H
S
E
I
K
T
L
E
R
I
E
I
I
R
D
L
R
L
G
K
Y
D
V
L
V
G
I
N
L
L
R
E
G
L
D
I
P
E
V
S
L
V
A
-------
I
L
D
A
D
K
E
G
F
L
R
S
E
R
S
L
I
Q
T
I
G
R
A
A
R
-
N
A
E
G
R
V
I
M
Y
A
D
K
I
T
K
S
M
E
I
A
I
N
E
T
K
R
R
R
-
E
Q
Q
E
R
F
N
E
E
H
G
I
T
P
K
T
I
N
----------------------------
K
----
K
E
R
Q
K
V
V
E
Q
M
E
H
E
M
K
E
A
A
K
A
L
D
F
E
R
A
A
E
L
R
D
L
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
90.08
79%
-95
- C3 -
2NMV
3
?
A:
[3-654]
---
D
R
F
E
L
V
-
K
Y
Q
P
Q
G
D
Q
P
K
A
I
E
K
L
V
K
G
I
Q
E
G
K
K
H
Q
T
L
L
G
A
-
T
G
T
G
K
T
F
T
V
S
N
L
I
K
E
V
N
-
K
P
--
T
L
V
I
A
H
N
K
T
L
A
G
Q
L
Y
S
E
F
K
E
F
F
P
N
N
A
V
E
Y
F
V
S
Y
Y
D
Y
Y
Q
P
E
A
Y
V
P
Q
T
D
T
F
I
E
K
D
A
S
I
N
D
E
I
D
K
L
R
H
S
A
T
S
A
L
F
E
-
R
R
D
V
I
I
I
A
S
V
S
-
C
I
Y
G
L
G
S
P
E
E
Y
R
E
M
V
-
V
S
L
R
T
E
M
E
I
E
R
N
E
L
L
R
K
L
V
D
I
Q
Y
A
R
N
D
I
D
F
Q
R
G
T
F
R
V
R
G
D
V
V
E
I
F
P
A
S
-
R
D
E
H
C
V
R
V
E
F
F
G
D
E
I
E
R
I
R
-
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V
D
A
L
T
G
E
I
L
G
D
R
D
H
V
A
I
F
P
A
S
H
F
V
T
R
A
E
K
M
E
K
A
I
Q
N
I
E
K
E
L
E
E
Q
L
K
V
M
H
E
N
G
K
L
L
E
A
Q
R
L
E
Q
R
T
R
Y
D
L
E
M
M
R
E
M
G
F
C
S
G
I
E
N
Y
S
R
H
L
T
L
R
P
P
G
S
T
P
Y
T
L
L
D
Y
F
P
D
D
F
M
I
V
V
D
E
S
H
V
T
I
P
Q
V
R
G
M
F
N
G
D
Q
A
R
K
Q
V
L
V
D
-
H
G
F
R
L
--
P
S
A
L
D
N
R
P
L
R
F
E
E
F
E
K
H
M
--
H
N
I
V
Y
V
S
--
A
T
P
G
P
Y
E
I
E
---
H
T
D
E
M
V
E
Q
I
I
R
P
T
G
L
L
D
P
L
I
D
V
-
R
P
I
E
G
Q
I
D
D
L
I
G
E
I
Q
A
R
I
E
R
N
E
R
-
V
L
V
T
T
L
T
K
K
M
S
E
D
L
T
D
Y
L
K
E
I
G
I
K
V
N
Y
L
--
H
S
E
I
K
T
L
E
R
I
E
I
I
R
D
L
R
L
G
K
Y
D
V
L
V
G
I
N
L
L
R
E
G
L
D
I
P
E
V
S
L
V
A
-------
I
L
D
A
D
K
E
G
F
L
R
S
E
R
S
L
I
Q
T
I
G
R
A
A
R
-
N
A
E
G
R
V
I
M
Y
A
D
K
I
T
K
S
M
E
I
A
I
N
E
T
K
R
R
R
-
E
Q
Q
E
R
F
N
E
E
H
G
I
T
P
K
T
I
N
----------------------------
K
----
K
E
R
Q
K
V
V
E
Q
M
E
H
E
M
K
E
A
A
K
A
L
D
F
E
R
A
A
E
L
R
D
L
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
88.94
77%
-93
- C3 -
1T5L
2
UVRB_BACCA
B:
[1-595]
-
V
E
G
R
F
Q
L
V
A
P
Y
E
P
Q
G
D
Q
P
Q
A
I
A
K
L
V
D
G
L
R
R
G
V
K
H
Q
T
L
L
G
A
-
T
G
T
G
K
T
F
T
I
S
N
V
I
A
Q
V
N
-
K
P
--
T
L
V
I
A
H
N
K
T
L
A
G
Q
L
Y
S
E
L
K
E
F
F
P
H
N
A
V
E
Y
F
V
S
Y
Y
D
Y
A
Q
P
E
A
Y
V
P
Q
T
D
T
Y
I
E
K
D
A
K
I
N
D
E
I
D
K
L
R
H
S
A
T
S
A
L
F
E
-
R
R
D
V
I
I
V
A
S
V
S
-
C
I
Y
G
L
G
S
P
E
E
Y
R
E
L
V
-
V
S
L
R
V
G
M
E
I
E
R
N
A
L
L
R
R
L
V
D
I
Q
Y
D
R
N
D
I
D
F
R
R
G
T
F
R
V
R
G
D
V
V
E
I
F
P
A
S
-
R
D
E
H
C
I
R
V
E
F
F
G
D
E
I
E
R
I
R
-
E
V
D
A
L
T
G
E
V
L
G
E
R
E
H
V
A
I
F
P
A
S
H
F
V
T
R
E
E
K
M
R
L
A
I
Q
N
I
E
Q
E
L
E
E
R
L
A
E
L
R
A
Q
G
K
L
L
E
A
Q
R
L
E
Q
R
T
R
Y
D
L
E
M
M
R
E
M
G
F
C
S
G
I
E
N
Y
S
R
H
L
A
L
R
P
P
G
S
T
P
Y
T
L
L
D
Y
F
P
D
D
F
L
I
I
V
D
E
S
H
V
T
L
P
Q
L
R
G
M
Y
N
G
D
R
A
R
K
Q
V
L
V
D
-
H
G
F
R
L
--
P
S
A
L
D
N
R
P
L
T
F
E
E
F
E
Q
K
I
--
N
Q
I
I
Y
V
S
--
A
T
P
G
P
Y
E
L
E
---
H
S
P
G
V
V
E
Q
I
I
R
P
T
G
L
L
D
P
T
I
D
V
-
R
P
T
K
G
Q
I
D
D
L
I
G
E
I
R
E
R
V
E
R
N
E
R
-
T
L
V
T
T
L
T
K
K
M
A
E
D
L
T
D
Y
L
K
E
A
G
I
K
V
A
Y
L
--
H
S
E
I
K
T
L
E
R
I
E
I
I
R
D
L
R
L
G
K
Y
D
V
L
V
G
I
N
L
L
R
E
G
L
D
I
P
E
V
S
L
V
A
-------
I
L
D
A
D
K
E
G
F
L
R
S
E
R
S
L
I
Q
T
I
G
R
A
A
R
-
N
A
N
G
H
V
I
M
Y
A
D
T
I
T
K
S
M
E
I
A
I
Q
E
T
K
R
R
R
-
A
I
Q
E
E
Y
N
R
K
H
G
I
V
P
R
T
V
K
K
E
I
R
D
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
88.85
77%
-93
- C3 -
1T5L
2
UVRB_BACCA
A:
[1-595]
-
V
E
G
R
F
Q
L
V
A
P
Y
E
P
Q
G
D
Q
P
Q
A
I
A
K
L
V
D
G
L
R
R
G
V
K
H
Q
T
L
L
G
A
-
T
G
T
G
K
T
F
T
I
S
N
V
I
A
Q
V
N
-
K
P
--
T
L
V
I
A
H
N
K
T
L
A
G
Q
L
Y
S
E
L
K
E
F
F
P
H
N
A
V
E
Y
F
V
S
Y
Y
D
Y
A
Q
P
E
A
Y
V
P
Q
T
D
T
Y
I
E
K
D
A
K
I
N
D
E
I
D
K
L
R
H
S
A
T
S
A
L
F
E
-
R
R
D
V
I
I
V
A
S
V
S
-
C
I
Y
G
L
G
S
P
E
E
Y
R
E
L
V
-
V
S
L
R
V
G
M
E
I
E
R
N
A
L
L
R
R
L
V
D
I
Q
Y
D
R
N
D
I
D
F
R
R
G
T
F
R
V
R
G
D
V
V
E
I
F
P
A
S
-
R
D
E
H
C
I
R
V
E
F
F
G
D
E
I
E
R
I
R
-
E
V
D
A
L
T
G
E
V
L
G
E
R
E
H
V
A
I
F
P
A
S
H
F
V
T
R
E
E
K
M
R
L
A
I
Q
N
I
E
Q
E
L
E
E
R
L
A
E
L
R
A
Q
G
K
L
L
E
A
Q
R
L
E
Q
R
T
R
Y
D
L
E
M
M
R
E
M
G
F
C
S
G
I
E
N
Y
S
R
H
L
A
L
R
P
P
G
S
T
P
Y
T
L
L
D
Y
F
P
D
D
F
L
I
I
V
D
E
S
H
V
T
L
P
Q
L
R
G
M
Y
N
G
D
R
A
R
K
Q
V
L
V
D
-
H
G
F
R
L
--
P
S
A
L
D
N
R
P
L
T
F
E
E
F
E
Q
K
I
--
N
Q
I
I
Y
V
S
--
A
T
P
G
P
Y
E
L
E
---
H
S
P
G
V
V
E
Q
I
I
R
P
T
G
L
L
D
P
T
I
D
V
-
R
P
T
K
G
Q
I
D
D
L
I
G
E
I
R
E
R
V
E
R
N
E
R
-
T
L
V
T
T
L
T
K
K
M
A
E
D
L
T
D
Y
L
K
E
A
G
I
K
V
A
Y
L
--
H
S
E
I
K
T
L
E
R
I
E
I
I
R
D
L
R
L
G
K
Y
D
V
L
V
G
I
N
L
L
R
E
G
L
D
I
P
E
V
S
L
V
A
-------
I
L
D
A
D
K
E
G
F
L
R
S
E
R
S
L
I
Q
T
I
G
R
A
A
R
-
N
A
N
G
H
V
I
M
Y
A
D
T
I
T
K
S
M
E
I
A
I
Q
E
T
K
R
R
R
-
A
I
Q
E
E
Y
N
R
K
H
G
I
V
P
R
T
V
K
K
E
I
R
D
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
88.58
77%
-92
- C3 -
3UWX
-
?
B:
[26-620]
-
V
E
G
R
F
Q
L
V
S
P
Y
E
P
Q
G
D
Q
P
Q
A
I
A
K
L
V
D
G
L
R
L
G
V
K
H
Q
T
L
L
G
A
-
T
G
T
G
K
T
F
T
I
S
N
V
I
A
Q
V
N
-
K
P
--
T
L
V
I
A
H
N
K
T
L
A
G
Q
L
H
S
E
L
K
E
F
F
P
H
N
A
V
E
Y
F
V
S
Y
Y
D
Y
Y
Q
P
E
A
Y
V
P
Q
T
D
T
Y
I
E
K
D
A
K
I
N
D
E
I
D
K
L
R
H
S
A
T
S
A
L
F
E
-
R
R
D
V
I
I
V
A
S
V
S
-
C
I
Y
G
L
G
S
P
E
E
Y
R
E
L
V
-
V
S
L
R
V
G
M
E
I
E
R
N
A
L
L
R
R
L
V
D
I
Q
Y
D
R
N
D
I
D
F
R
R
G
T
F
R
V
R
G
D
V
V
E
I
F
P
A
S
-
R
D
E
H
C
I
R
V
E
F
F
G
D
E
I
E
R
I
R
-
E
V
D
A
L
T
G
E
V
L
G
E
R
E
H
V
A
I
F
P
A
S
H
F
V
T
R
E
E
K
M
R
L
A
I
Q
N
I
E
Q
E
L
E
E
R
L
A
E
L
R
A
Q
G
K
L
L
E
A
Q
R
L
E
Q
R
T
R
Y
D
L
E
M
M
R
E
M
G
F
C
S
G
I
E
N
Y
S
R
H
L
A
L
R
P
P
G
S
T
P
Y
T
L
L
D
Y
F
P
D
D
F
L
I
I
V
D
E
S
H
V
T
L
P
Q
L
R
G
M
Y
N
G
D
R
A
R
K
Q
V
L
V
D
-
H
G
F
R
L
--
P
S
A
L
D
N
R
P
L
T
F
E
E
F
E
Q
K
I
--
N
Q
I
I
Y
I
S
--
A
T
P
G
P
Y
E
L
E
---
H
S
P
G
V
V
E
Q
I
I
R
P
T
G
L
L
D
P
T
I
D
V
-
R
P
T
K
G
Q
I
D
D
L
I
G
E
I
H
E
R
V
E
R
N
E
R
-
T
L
V
T
T
L
T
K
K
M
A
E
D
L
T
D
Y
L
K
E
A
G
I
K
V
A
Y
L
--
H
S
E
I
K
T
L
E
R
I
E
I
I
R
D
L
R
L
G
K
Y
D
V
L
V
G
I
N
L
L
R
E
G
L
D
I
P
E
V
S
L
V
A
-------
I
L
D
A
D
K
E
G
F
L
R
S
E
R
S
L
I
Q
T
I
G
R
A
A
R
-
N
A
N
G
H
V
I
M
Y
A
D
T
I
T
K
S
M
E
I
A
I
Q
E
T
K
R
R
R
-
A
I
Q
E
E
Y
N
R
K
H
G
I
V
P
R
T
V
K
K
E
I
R
D
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
87.48
79%
-95
- C3 -
3V4R
2
UVRB_BACSU
A:
[9-596]
---
D
R
F
E
L
V
S
K
Y
Q
P
Q
G
D
Q
P
K
A
I
E
K
L
V
K
G
I
Q
E
G
K
K
H
Q
T
L
L
G
A
-
T
G
T
G
K
T
F
T
V
S
N
L
I
K
E
V
N
-
K
P
--
T
L
V
I
A
H
N
K
T
L
A
G
Q
L
Y
S
E
F
K
E
F
F
P
N
N
A
V
E
Y
F
V
S
Y
Y
D
Y
Y
Q
P
E
A
Y
V
P
Q
T
D
T
F
I
E
K
D
A
S
I
N
D
E
I
D
K
L
R
H
S
A
T
S
A
L
F
E
-
R
R
D
V
I
I
I
A
S
V
S
-
C
I
Y
G
L
G
S
P
E
E
Y
R
E
M
V
-
V
S
L
R
T
E
M
E
I
E
R
N
E
L
L
R
K
L
V
D
I
Q
Y
A
R
N
D
I
D
F
Q
R
G
T
F
R
V
R
G
D
V
V
E
I
F
P
---
R
D
E
H
C
V
R
V
E
F
F
G
D
E
I
E
R
I
R
-
E
V
D
A
L
T
G
E
I
L
G
D
R
D
H
V
A
I
F
P
A
S
H
F
V
T
R
A
E
K
M
E
K
A
I
Q
N
I
E
K
E
L
E
E
Q
L
K
V
M
H
E
N
G
K
L
L
E
A
Q
R
L
E
Q
R
T
R
Y
D
L
E
M
M
R
E
M
G
F
C
S
G
I
E
N
Y
S
R
H
L
T
L
R
P
P
G
S
T
P
Y
T
L
L
D
Y
F
P
D
D
F
M
I
V
V
D
E
S
H
V
T
I
P
Q
V
R
G
M
F
N
G
D
Q
A
R
K
Q
V
L
V
D
-
H
G
F
R
L
--
P
S
A
L
D
N
R
P
L
R
F
E
E
F
E
K
H
M
--
H
N
I
V
Y
V
S
--
A
T
P
G
P
Y
E
I
E
---
H
T
D
E
M
V
E
Q
I
I
R
P
T
G
L
L
D
P
L
I
D
V
-
R
P
I
E
G
Q
I
D
D
L
I
G
E
I
Q
A
R
I
E
R
N
E
R
-
V
L
V
T
T
L
T
K
K
M
S
E
D
L
T
D
Y
L
K
E
I
G
I
K
V
N
Y
L
--
H
S
E
I
K
T
L
E
R
I
E
I
I
R
D
L
R
L
G
K
Y
D
V
L
V
G
I
N
L
L
R
E
G
L
D
I
P
E
V
S
L
V
A
-------
I
L
D
A
D
K
E
G
F
L
R
S
E
R
S
L
I
Q
T
I
G
R
A
A
R
-
N
A
E
G
R
V
I
M
Y
A
D
K
I
T
K
S
M
E
I
A
I
N
E
T
K
R
R
R
-
E
Q
Q
E
R
F
N
E
E
H
G
I
T
P
K
T
I
N
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
86.63
79%
-93
- C3 -
3V4R
2
?
B:
[9-595]
---
D
R
F
E
L
V
S
K
Y
Q
P
Q
G
D
Q
P
K
A
I
E
K
L
V
K
G
I
Q
E
G
K
K
H
Q
T
L
L
G
A
-
T
G
T
G
K
T
F
T
V
S
N
L
I
K
E
V
N
-
K
P
--
T
L
V
I
A
H
N
K
T
L
A
G
Q
L
Y
S
E
F
K
E
F
F
P
N
N
A
V
E
Y
F
V
S
Y
Y
D
Y
Y
Q
P
E
A
Y
V
P
Q
T
D
T
F
I
E
K
D
A
S
I
N
D
E
I
D
K
L
R
H
S
A
T
S
A
L
F
E
-
R
R
D
V
I
I
I
A
S
V
S
-
C
I
Y
G
L
G
S
P
E
E
Y
R
E
M
V
-
V
S
L
R
T
E
M
E
I
E
R
N
E
L
L
R
K
L
V
D
I
Q
Y
A
R
N
D
I
D
F
Q
R
G
T
F
R
V
R
G
D
V
V
E
I
F
P
A
S
-
R
D
E
H
C
V
R
V
E
F
F
G
D
E
I
E
R
I
R
-
E
V
D
A
L
T
G
E
I
L
G
D
R
D
H
V
A
I
F
P
A
S
--------
M
E
K
A
I
Q
N
I
E
K
E
L
E
E
Q
L
K
V
M
H
E
N
G
K
L
L
E
A
Q
R
L
E
Q
R
T
R
Y
D
L
E
M
M
R
E
M
G
F
C
S
G
I
E
N
Y
S
R
H
L
T
L
R
P
P
G
S
T
P
Y
T
L
L
D
Y
F
P
D
D
F
M
I
V
V
D
E
S
H
V
T
I
P
Q
V
R
G
M
F
N
G
D
Q
A
R
K
Q
V
L
V
D
-
H
G
F
R
L
--
P
S
A
L
D
N
R
P
L
R
F
E
E
F
E
K
H
M
--
H
N
I
V
Y
V
S
--
A
T
P
G
P
Y
E
I
E
---
H
T
D
E
M
V
E
Q
I
I
R
P
T
G
L
L
D
P
L
I
D
V
-
R
P
I
E
G
Q
I
D
D
L
I
G
E
I
Q
A
R
I
E
R
N
E
R
-
V
L
V
T
T
L
T
K
K
M
S
E
D
L
T
D
Y
L
K
E
I
G
I
K
V
N
Y
L
--
H
S
E
I
K
T
L
E
R
I
E
I
I
R
D
L
R
L
G
K
Y
D
V
L
V
G
I
N
L
L
R
E
G
L
D
I
P
E
V
S
L
V
A
-------
I
L
D
A
D
K
E
G
F
L
R
S
E
R
S
L
I
Q
T
I
G
R
A
A
R
-
N
A
E
G
R
V
I
M
Y
A
D
K
I
T
K
S
M
E
I
A
I
N
E
T
K
R
R
R
-
E
Q
Q
E
R
F
N
E
E
H
G
I
T
P
K
T
I
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
86.62
77%
-92
- C3 -
2FDC
2
UVRB_BACCA
B:
[1-593]
-
V
E
G
R
F
Q
L
V
A
P
Y
E
P
Q
G
D
Q
P
Q
A
I
A
K
L
V
D
G
L
R
R
G
V
K
H
Q
T
L
L
G
A
-
T
G
T
G
K
T
F
T
I
S
N
V
I
A
Q
V
N
-
K
P
--
T
L
V
I
A
H
N
K
T
L
A
G
Q
L
Y
S
E
L
K
E
F
F
P
H
N
A
V
E
Y
F
V
S
Y
Y
D
Y
Y
Q
P
E
A
Y
V
P
Q
T
D
T
Y
I
E
K
D
A
K
I
N
D
E
I
D
K
L
R
H
S
A
T
S
A
L
F
E
-
R
R
D
V
I
I
V
A
S
V
S
-
C
I
Y
G
L
G
S
P
E
E
Y
R
E
L
V
-
V
S
L
R
V
G
M
E
I
E
R
N
A
L
L
R
R
L
V
D
I
Q
Y
D
R
N
D
I
D
F
R
R
G
T
F
R
V
R
G
D
V
V
E
I
F
P
A
S
-
R
D
E
H
C
I
R
V
E
F
F
G
D
E
I
E
R
I
R
-
E
V
D
A
L
T
G
E
V
L
G
E
R
E
H
V
A
I
F
P
A
S
H
F
V
T
R
E
E
K
M
R
L
A
I
Q
N
I
E
Q
E
L
E
E
R
L
A
E
L
R
A
Q
G
K
L
L
E
A
Q
R
L
E
Q
R
T
R
Y
D
L
E
M
M
R
E
M
G
F
C
S
G
I
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N
Y
S
R
H
L
A
L
R
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P
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Y
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L
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Y
F
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F
L
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I
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Q
L
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G
M
Y
N
G
D
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A
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V
L
V
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-
H
G
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--
P
S
A
L
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N
R
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L
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F
E
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F
E
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K
I
--
N
Q
I
I
Y
V
S
--
A
T
P
G
P
Y
E
L
E
---
H
S
P
G
V
V
E
Q
I
I
R
P
T
G
L
L
D
P
T
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D
V
-
R
P
T
K
G
Q
I
D
D
L
I
G
E
I
R
E
R
V
E
R
N
E
R
-
T
L
V
T
T
L
T
K
K
M
A
E
D
L
T
D
Y
L
K
E
A
G
I
K
V
A
Y
L
--
H
--------
I
E
I
I
R
D
L
R
L
G
K
Y
D
V
L
V
G
I
N
L
L
R
E
G
L
D
I
P
E
V
S
L
V
A
-------
I
L
D
A
D
K
E
G
F
L
R
S
E
R
S
L
I
Q
T
I
G
R
A
A
R
-
N
A
N
G
H
V
I
M
Y
A
D
T
I
T
K
S
M
E
I
A
I
Q
E
T
K
R
R
R
-
A
I
Q
E
E
Y
N
R
K
H
G
I
V
P
R
T
V
K
K
E
I
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
84.19
79%
-85
- C3 -
1D9X
2
UVRB_BACCA
A:
[2-595]
--
E
G
R
F
Q
L
V
A
P
Y
E
P
Q
G
D
Q
P
Q
A
I
A
K
L
V
D
G
L
R
R
G
V
K
H
Q
T
L
L
G
A
-
T
G
T
G
K
T
F
T
I
S
N
V
I
A
Q
V
N
-
K
P
--
T
L
V
I
A
H
N
K
T
L
A
G
Q
L
Y
S
E
L
K
E
F
F
P
H
N
A
V
E
Y
F
V
S
Y
Y
D
Y
Y
Q
P
E
A
Y
V
P
Q
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D
T
Y
I
E
K
D
A
K
I
N
D
E
I
D
K
L
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H
S
A
T
S
A
L
F
E
-
R
R
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V
I
I
V
A
S
V
S
-
C
I
Y
G
L
G
S
P
E
E
Y
R
E
L
V
-
V
S
L
R
V
G
M
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N
A
L
L
R
R
L
V
D
I
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Y
D
R
N
D
I
--
F
R
G
T
F
R
V
R
G
D
V
V
E
I
F
P
A
S
-
R
D
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H
C
I
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V
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F
F
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D
E
I
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A
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V
-
D
--
A
L
T
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K
V
L
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E
H
V
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P
A
S
H
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V
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R
E
E
K
M
R
L
A
I
Q
N
I
E
Q
E
L
E
E
R
L
A
E
L
R
A
Q
G
K
L
L
E
A
Q
R
L
E
Q
R
T
R
Y
D
L
E
M
M
R
E
M
G
F
C
S
G
I
E
N
Y
S
R
H
L
A
L
R
P
P
G
S
T
P
Y
T
L
L
D
Y
F
P
D
D
F
L
I
I
V
D
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S
H
V
T
L
P
Q
L
R
G
M
Y
N
G
D
R
A
R
K
Q
V
L
V
D
-
H
G
F
R
L
--
P
S
A
L
D
N
R
P
L
T
F
E
E
F
E
Q
K
I
--
N
Q
I
I
Y
V
S
--
A
T
P
G
P
Y
E
L
E
H
S
P---
G
V
V
E
Q
I
I
R
P
T
G
L
L
D
P
T
I
D
V
-
R
P
T
K
G
Q
I
D
D
L
I
G
E
I
R
E
R
V
E
R
N
E
R
-
T
L
V
T
T
L
T
K
K
M
A
E
D
L
T
D
Y
L
K
E
A
G
I
K
V
A
Y
L
--
H
S
E
I
K
T
L
E
R
I
E
I
I
R
D
L
R
L
G
K
Y
D
V
L
V
G
I
N
L
L
R
E
G
L
D
I
P
E
V
S
L
V
A
-------
I
L
D
A
D
K
E
G
F
L
R
S
E
R
S
L
I
Q
T
I
G
R
A
A
R
N
A
-
N
G
H
V
I
M
Y
A
D
T
I
T
K
S
M
E
I
A
I
Q
E
T
K
R
R
R
-
A
I
Q
E
E
Y
N
R
K
H
G
I
V
P
R
T
V
K
K
E
I
R
D
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
83.30
77%
-81
- C3 -
1D9X
2
UVRB_BACCA
A:
[2-595]
--
E
G
R
F
Q
L
V
A
P
Y
E
P
Q
G
D
Q
P
Q
A
I
A
K
L
V
D
G
L
R
R
G
V
K
H
Q
T
L
L
G
A
-
T
G
T
G
K
T
F
T
I
S
N
V
I
A
Q
V
N
-
K
P
--
T
L
V
I
A
H
N
K
T
L
A
G
Q
L
Y
S
E
L
K
E
F
F
P
H
N
A
V
E
Y
F
V
S
Y
Y
D
Y
Y
Q
P
E
A
Y
V
P
Q
T
D
T
Y
I
E
K
D
A
K
I
N
D
E
I
D
K
L
R
H
S
A
T
S
A
L
F
E
-
R
R
D
V
I
I
V
A
S
V
S
-
C
I
Y
G
L
G
S
P
E
E
Y
R
E
L
V
-
V
S
L
R
V
G
M
E
I
E
R
N
A
L
L
R
R
L
V
D
I
Q
Y
D
R
N
D
I
-
F
-
R
G
T
F
R
V
R
G
D
V
V
E
I
F
P
A
S
-
R
D
E
H
C
I
R
V
E
F
F
G
D
E
I
E
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E
V
D
A
L
T
G
K
V
L
G
E
R
E
H
V
A
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P
A
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H
F
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T
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E
E
K
M
R
L
A
I
Q
N
I
E
Q
E
L
E
E
R
L
A
E
L
R
A
Q
G
K
L
L
E
A
Q
R
L
E
Q
R
T
R
Y
D
L
E
M
M
R
E
M
G
F
C
S
G
I
E
N
Y
S
R
H
L
A
L
R
P
P
G
S
T
P
Y
T
L
L
D
Y
F
P
D
D
F
L
I
I
V
D
E
S
H
V
T
L
P
Q
L
R
G
M
Y
N
G
D
R
A
R
K
Q
V
L
V
D
-
H
G
F
R
L
--
P
S
A
L
D
N
R
P
L
T
F
E
E
F
E
Q
K
I
--
N
Q
I
I
Y
V
S
--
A
T
P
G
P
Y
E
L
E
---
H
S
P
G
V
V
E
Q
I
I
R
P
T
G
L
L
D
P
T
I
D
V
-
R
P
T
K
G
Q
I
D
D
L
I
G
E
I
R
E
R
V
E
R
N
E
R
-
T
L
V
T
T
L
T
K
K
M
A
E
D
L
T
D
Y
L
K
E
A
G
I
K
V
A
Y
L
--
H
S
E
I
K
T
L
E
R
I
E
I
I
R
D
L
R
L
G
K
Y
D
V
L
V
G
I
N
L
L
R
E
G
L
D
I
P
E
V
S
L
V
A
-------
I
L
D
A
D
K
E
G
F
L
R
S
E
R
S
L
I
Q
T
I
G
R
A
A
R
-
N
A
N
G
H
V
I
M
Y
A
D
T
I
T
K
S
M
E
I
A
I
Q
E
T
K
R
R
R
-
A
I
Q
E
E
Y
N
R
K
H
G
I
V
P
R
T
V
K
K
E
I
R
D
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
82.87
77%
-79
- C3 -
1D9Z
4
UVRB_BACCA
A:
[2-594]
--
E
G
R
F
Q
L
V
A
P
Y
E
P
Q
G
D
Q
P
Q
A
I
A
K
L
V
D
G
L
R
R
G
V
K
H
Q
T
L
L
G
A
-
T
G
T
G
K
T
F
T
I
S
N
V
I
A
Q
V
N
-
K
P
--
T
L
V
I
A
H
N
K
T
L
A
G
Q
L
Y
S
E
L
K
E
F
F
P
H
N
A
V
E
Y
F
V
S
Y
Y
D
Y
Y
Q
P
E
A
Y
V
P
Q
T
D
T
Y
I
E
K
D
A
K
I
N
D
E
I
D
K
L
R
H
S
A
T
S
A
L
F
E
-
R
R
D
V
I
I
V
A
S
V
S
-
C
I
Y
G
L
G
S
P
E
E
Y
R
E
L
V
-
V
S
L
R
V
G
M
E
I
E
R
N
A
L
L
R
R
L
V
D
I
Q
Y
D
R
N
D
I
-
F
-
R
G
T
F
R
V
R
G
D
V
V
E
I
F
P
A
S
-
R
D
E
H
C
I
R
V
E
F
F
G
D
E
I
E
--
R
-
E
V
D
A
L
T
G
K
V
L
G
E
R
E
H
V
A
I
F
P
A
S
H
F
V
T
R
E
E
K
M
R
L
A
I
Q
N
I
E
Q
E
L
E
E
R
L
A
E
L
R
A
Q
G
K
L
L
E
A
Q
R
L
E
Q
R
T
R
Y
D
L
E
M
M
R
E
M
G
F
C
S
G
I
E
N
Y
S
R
H
L
A
L
R
P
P
G
S
T
P
Y
T
L
L
D
Y
F
P
D
D
F
L
I
I
V
D
E
S
H
V
T
L
P
Q
L
R
G
M
Y
N
G
D
R
A
R
K
Q
V
L
V
D
-
H
G
F
R
L
--
P
S
A
L
D
N
R
P
L
T
F
E
E
F
E
Q
K
I
--
N
Q
I
I
Y
V
S
--
A
T
P
G
P
Y
E
L
E
---
H
S
P
G
V
V
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Q
I
I
R
P
T
G
L
L
D
P
T
I
D
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-
R
P
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Q
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D
L
I
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E
I
R
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V
E
R
N
E
R
-
T
L
V
T
T
L
T
K
K
M
A
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D
L
T
D
Y
L
K
E
A
G
I
K
V
A
Y
L
--
H
S
E
I
K
T
L
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R
I
E
I
I
R
D
L
R
L
G
K
Y
D
V
L
V
G
I
N
L
L
R
E
G
L
D
I
P
E
V
S
L
V
A
-------
I
L
D
A
D
K
E
G
F
L
R
S
E
R
S
L
I
Q
T
I
G
R
A
A
R
-
N
A
N
G
H
V
I
M
Y
A
D
T
I
T
K
S
M
E
I
A
I
Q
E
T
K
R
R
R
-
A
I
Q
E
E
Y
N
R
K
H
G
I
V
P
R
T
V
K
K
E
I
R
D
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
78.20
57%
-83
- C3 -
1D2M
4
UVRB_THET8
A:
[2-583]
----
T
F
R
Y
-
R
G
P
S
P
K
G
D
Q
P
K
A
I
A
G
L
V
E
A
L
R
D
G
E
R
F
V
T
L
L
G
A
-
T
G
T
G
K
T
V
T
M
A
K
V
I
E
A
L
G
-
R
P
--
A
L
V
L
A
P
N
K
I
L
A
A
Q
L
A
A
E
F
R
E
L
F
P
E
N
A
V
E
Y
F
I
S
Y
Y
D
Y
Y
Q
P
E
A
Y
V
P
G
K
D
L
Y
I
E
K
D
A
S
I
N
P
E
I
E
R
L
R
H
S
T
T
R
S
L
L
T
-
R
R
D
V
I
V
V
A
S
V
S
-
A
I
Y
G
L
G
D
P
R
E
Y
R
A
--------
R
N
L
V
V
R
E
V
L
L
E
R
L
L
E
L
G
Y
Q
R
N
D
I
D
L
S
P
G
R
F
R
A
K
G
E
V
L
E
I
F
P
A
Y
-
E
T
E
P
-
I
R
V
E
L
------------------------
G
F
V
L
F
P
A
T
H
Y
L
S
P
E
G
-
L
E
E
I
L
K
E
I
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K
E
L
W
E
R
V
R
Y
F
E
E
R
G
E
V
L
Y
A
Q
R
L
K
E
R
T
L
Y
D
L
E
M
L
R
V
M
G
T
C
P
G
V
E
N
Y
A
R
Y
F
T
G
K
A
P
G
E
P
P
Y
T
L
L
D
Y
F
P
E
D
F
L
V
F
L
D
E
S
H
V
T
V
P
Q
L
Q
G
M
Y
R
G
D
Y
A
R
K
K
T
L
V
D
-
Y
G
F
R
L
--
P
S
A
L
D
N
R
P
L
R
F
E
E
F
L
E
R
V
--
S
Q
V
V
F
V
S
--
A
T
P
G
P
F
E
L
A
---
H
S
G
R
V
V
E
Q
I
I
R
P
T
G
L
L
D
P
L
V
R
V
-
K
P
T
E
N
Q
I
L
D
L
M
E
G
I
R
E
R
A
A
R
G
E
R
-
T
L
V
T
V
L
T
V
R
M
A
E
E
L
T
S
F
L
V
E
H
G
I
R
A
R
Y
L
--
H
H
E
L
D
A
F
K
R
Q
A
L
I
R
D
L
R
L
G
H
Y
D
C
L
V
G
I
N
L
L
R
E
G
L
D
I
P
E
V
S
L
V
A
-------
I
L
D
A
D
K
E
G
F
L
R
S
E
R
S
L
I
Q
T
I
G
R
A
A
R
-
N
A
R
G
E
V
W
L
Y
A
D
R
V
S
E
A
M
Q
R
A
I
E
E
T
N
R
R
R
-
A
L
Q
E
A
Y
N
L
E
H
G
I
T
P
E
T
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
78.03
77%
-87
- C3 -
2FDC
1
UVRB_BACCA
A:
[1-594]
-
V
E
G
R
F
Q
L
V
A
P
Y
E
P
Q
G
D
Q
P
Q
A
I
A
K
L
V
D
G
L
R
R
G
V
K
H
Q
T
L
L
G
A
-
T
G
T
G
K
T
F
T
I
S
N
V
I
A
Q
V
N
-
K
P
--
T
L
V
I
A
H
N
K
T
L
A
G
Q
L
Y
S
E
L
K
E
F
F
P
H
N
A
V
E
Y
F
V
S
Y
Y
D
Y
Y
Q
P
E
A
Y
V
P
Q
T
D
T
Y
I
E
K
D
A
K
I
N
D
E
I
D
K
L
R
H
S
A
T
S
A
L
F
E
-
R
R
D
V
I
I
V
A
S
V
S
-
C
I
Y
G
L
G
S
P
E
E
Y
R
E
L
V
-
V
-------------------------------------------------------------------------------------
I
F
P
A
S
H
F
V
T
R
E
E
K
M
R
L
A
I
Q
N
I
E
Q
E
L
E
E
R
L
A
E
L
R
A
Q
G
K
L
L
E
A
Q
R
L
E
Q
R
T
R
Y
D
L
E
M
M
R
E
M
G
F
C
S
G
I
E
N
Y
S
R
H
L
A
L
R
P
P
G
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T
P
Y
T
L
L
D
Y
F
P
D
D
F
L
I
I
V
D
E
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H
V
T
L
P
Q
L
R
G
M
Y
N
G
D
R
A
R
K
Q
V
L
V
D
-
H
G
F
R
L
--
P
S
A
L
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N
R
P
L
T
F
E
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F
E
Q
K
I
--
N
Q
I
I
Y
V
S
--
A
T
P
G
P
Y
E
L
E
---
H
S
P
G
V
V
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I
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P
T
G
L
L
D
P
T
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D
V
-
R
P
T
K
G
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D
L
I
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I
R
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R
V
E
R
N
E
R
-
T
L
V
T
T
L
T
K
K
M
A
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D
L
T
D
Y
L
K
E
A
G
I
K
V
A
Y
L
--
H
------
E
R
I
E
I
I
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D
L
R
L
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K
Y
D
V
L
V
G
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N
L
L
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L
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P
E
V
S
L
V
A
-------
I
L
D
A
D
K
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F
L
R
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E
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S
L
I
Q
T
I
G
R
A
A
R
-
N
A
N
G
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M
Y
A
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T
I
T
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M
E
I
A
I
Q
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R
R
R
-
A
I
Q
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Y
N
R
K
H
G
I
V
P
R
T
V
K
K
E
I
R
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
64.43
76%
-82
- C3 -
1D9X
1
UVRB_BACCA
A:
[2-414]
--
E
G
R
F
Q
L
V
A
P
Y
E
P
Q
G
D
Q
P
Q
A
I
A
K
L
V
D
G
L
R
R
G
V
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H
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T
L
L
G
A
-
T
G
T
G
K
T
F
T
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S
N
V
I
A
Q
V
N
---KP
T
L
V
I
A
H
N
K
T
L
A
G
Q
L
Y
S
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L
K
E
F
F
P
H
N
A
V
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Y
F
V
S
Y
Y
D
Y
Y
Q
P
E
A
Y
V
P
Q
T
D
T
Y
I
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K
D
A
K
I
N
D
E
I
D
K
L
R
H
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A
T
S
A
L
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-
R
R
D
V
I
I
V
A
S
V
S
-
C
I
Y
G
L
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V
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L
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V
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L
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A
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K
L
L
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Y
D
L
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M
M
R
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A
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Y
N
G
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--
P
S
A
L
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N
R
P
L
T
F
E
E
F
E
Q
K
I
--
N
Q
I
I
Y
V
S
--
A
T
P
--------------------------------------------------------------
G
P
Y
E
L
E
H
S
P
--------------------------------------------------------------------------------------------------------------------------------------
G
V
V
E
Q
I
I
R
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
Fugue
50.64
20%
-58
- C3 -
2EYQ
5
MFD_ECOLI
A:
[5-1150]
P
E
Q
Y
R
Y
T
L
P
V
K
---
A
G
E
Q
R
------------------
L
L
G
E
L
T
G
A
A
C
A
T
L
V
A
E
I
A
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H
A
-
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--
V
V
L
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A
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D
M
Q
N
A
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L
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D
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I
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Q
F
-
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D
Q
M
V
M
N
L
A
D
W
-------------
E
T
L
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Y
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S
P
H
Q
D
I
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S
R
L
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T
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Q
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-
M
Q
R
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V
L
I
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N
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T
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S
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Y
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F
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V
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Q
R
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L
L
P
A
H
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P
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----
K
A
A
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K
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D
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H
I
Y
Q
Q
V
S
K
G
T
L
P
-------------
A
G
I
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Y
W
Q
P
L
F
F
S
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P
L
P
----
P
L
F
S
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A
N
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T
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---
L
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--
K
N
W
P
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--
L
K
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H
L
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-
T
---
K
A
A
N
A
N
L
G
F
Q
K
L
P
D
L
---------
A
V
Q
A
Q
Q
K
A
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L
D
A
L
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F
L
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F
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A
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L
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R
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R
Y
L
M
I
G
A
A
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H
G
F
V
D
T
V
R
N
------------
L
A
L
I
C
-------
E
S
D
L
L
G
E
R
V
A
R
R
R
Q
D
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R
R
T
I
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V
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L
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G
R
Y
A
--------------
G
M
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L
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A
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A
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VGFGKT
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V
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SRFRS
A
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A
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GKID
I
L
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T
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L
L
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DVKFKDLG
L
L
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D
EEHRFG
V
R
H
K
E
R
I
K
A
M
R
AN
V
D
I
L
T
L
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ATPIP
R
T
L
N
M
A
M
SGM
R
D
L
S
I
IATPPARR
L
A
V
K
T
F
V
R
E
YD
S
M
V
V
R
E
A
I
L
R
E
I
L
R
G
G
Q
V
Y
Y
L
Y
NDVEN
I
Q
K
A
A
E
R
L
A
E
L
V
PE
A
R
I
A
I
G
H
G
QMR
E
R
E
L
E
R
V
M
N
D
F
H
H
QRFN
V
L
V
C
TTIIETGIDIPTAN
T
I
I
I
ERADHFG
L
A
Q
L
H
Q
L
R
G
R
V
G
R
S
H
H
Q
A
Y
A
W
LLTPHPKAMT
T
D
A
Q
K
R
L
E
A
I
A
S
LEDLGA
G
F
A
L
A
T
H
D
L
E
I
R
G
A
G
E
L
L
G
E
E
Q
S
G
S
M
E
T
IG
F
S
L
Y
M
E
L
L
E
N
A
V
D
A
L
K
A
GREPSLEDLTSQQ
T
E
V
E
LR
M
P
S
L
L
P
DDFIPD
V
N
T
R
L
S
F
Y
K
R
I
A
S
AKT
E
N
E
L
E
E
I
K
V
E
L
I
D
R
FGLLP
D
P
A
R
T
L
L
D
I
A
R
L
R
Q
Q
A
Q
K
L
GIR
K
L
E
G
N
EK
G
G
V
I
E
F
A
EKNHVN
P
A
W
L
I
G
L
L
Q
KQPQH
Y
R
L
D
G
PT
R
L
K
F
I
Q
DLSE
R
K
T
R
I
E
W
V
R
Q
F
M
R
E
L
E
E
N
AI
38
Fugue
46.07
19%
-50
- C3 -
3HJH
1
MFD_ECOLI
A:
[5-450]
------
Y
R
Y
T
L
P
V
K
A
G
E
-----------------
Q
R
L
L
G
E
L
-
T
G
A
A
C
A
T
L
V
A
E
I
A
E
R
H
A
-
G
P
--
V
V
L
I
A
P
D
M
Q
N
A
L
R
L
H
D
E
I
S
Q
F
T
D
Q
M
-----
V
M
N
L
A
D
W
E
T
L
P
Y
---------
D
S
F
S
P
H
Q
D
I
I
S
S
R
L
S
T
L
Y
Q
L
P
T
M
Q
R
G
V
L
I
V
P
V
N
T
-
L
M
Q
R
V
C
P
H
S
F
L
H
G
H
A
-
L
V
M
K
K
G
Q
R
L
S
R
D
A
L
R
T
Q
L
D
S
A
G
Y
R
H
V
D
Q
V
M
E
H
G
E
Y
A
T
R
G
A
L
L
D
L
F
P
M
G
--
S
E
L
P
Y
R
L
D
F
F
D
D
E
I
D
S
L
R
-
V
F
D
V
D
S
Q
R
T
L
E
E
V
E
A
I
N
L
L
P
A
H
E
F
P
T
-----------------
D
K
A
A
I
E
L
F
R
S
Q
W
R
D
T
F
E
V
K
R
D
P
E
H
I
Y
Q
Q
V
S
K
G
T
L
P
A
G
I
E
Y
W
Q
P
L
F
F
S
E
P
L
P
----
P
L
F
S
Y
F
P
A
N
T
L
L
V
N
T
G
D
----------------------------
L
--
E
T
S
A
E
R
F
Q
A
D
T
L
A
R
F
E
N
R
--
G
V
----------------------
D
P
M
R
P
L
L
P
P
Q
S
L
W
L
R
---------------
V
D
E
L
F
S
E
L
K
N
W
P
R
-
V
Q
L
K
T
E
H
L
P
T
K
A
A
N
A
N
L
---------------
G
F
Q
K
L
P
D
L
A
V
-----------------------------------------------
Q
A
Q
Q
K
A
P
L
D
A
L
R
K
F
L
E
-
T
F
D
G
P
V
V
F
S
V
------------
E
S
E
G
R
R
-
E
A
L
G
E
L
L
A
R
I
K
I
A
P
Q
R
I
M
----------------------
R
L
D
E
A
S
D
----
R
G
R
Y
L
M
I
G
A
A
E
H
G
F
V
D
T
V
R
N
L
A
L
I
C
E
S
D
L
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
HHSearch
44.95
18%
-70
- C3 -
3HJH
1
MFD_ECOLI
A:
[14-450]
--------------------------------
G
E
Q
R
L
L
G
E
L
-
T
G
A
A
C
A
T
L
V
A
E
I
A
E
R
-
H
A
G
P
--
V
V
L
I
A
P
D
M
Q
N
A
L
R
L
H
D
E
I
S
Q
F
T
D
-
Q
M
V
M
-------------
N
L
A
D
W
E
T
L
P
Y
D
S
F
S
P
H
Q
D
I
I
S
S
R
L
S
T
L
Y
Q
L
P
T
-
M
Q
R
G
V
L
I
V
P
V
N
T
L
M
Q
R
V
C
P
H
S
F
L
H
G
H
A
-
L
V
M
K
K
G
Q
R
L
S
R
D
A
L
R
T
Q
L
D
S
A
G
Y
R
H
V
D
Q
V
M
E
H
G
E
Y
A
T
R
G
A
L
L
D
L
F
P
M
G
-
S
-
E
L
P
Y
R
L
D
F
F
D
D
E
I
D
S
L
R
-
V
F
D
V
D
S
Q
R
T
L
E
E
V
E
A
I
N
L
L
P
A
H
E
F
P
T
D
K
A
A
I
E
L
F
R
S
Q
W
R
D
T
F
E
V
K
R
D
-----------------
P
E
H
I
Y
Q
Q
V
S
K
G
T
L
P
A
G
I
E
Y
W
Q
P
L
F
F
S
E
P
----
L
P
P
L
F
S
Y
F
P
A
N
T
-
L
L
-
V
N
T
G
D
L
E
T
S
A
E
R
F
Q
A
D
T
L
A
R
F
E
N
R
G
V
D
P
M
R
-
P
--
L
L
P
P
Q
S
L
W
L
R
V
D
E
L
F
S
E
L
K
N
W
P
R
V
Q
L
K
TE
H
L
P
T
K
A
-
A
N
--------
A
N
L
G
F
Q
K
--
L
--
P
D
L
A
V
Q
A
Q
Q
K
A
P
L
D
A
L
R
K
F
L
E
T
F
---
D
G
P
-
V
V
F
S
V
E
S
E
G
R
R
E
A
L
G
E
L
L
A
R
I
K
I
A
P
Q
R
I
--
M
R
L
----------
D
E
A
S
D
R
G
--
R
Y
L
M
I
G
A
A
E
H
G
F
V
D
T
V
R
N
L
A
L
-------
I
C
E
S
D
L
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
41.87
68%
-45
- C3 -
1D9X
1
UVRB_BACCA
A:
[415-595]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
L
L
D
P
T
I
D
V
R
-
P
--
T
K
---------
G
Q
I
D
D
L
I
G
E
I
R
E
R
V
E
R
N
E
R
-
T
L
V
T
T
L
T
K
K
M
A
E
D
L
T
D
Y
L
K
E
A
G
I
K
V
A
Y
L
--
H
S
E
I
K
T
L
E
R
I
E
I
I
R
D
L
R
L
G
K
Y
D
V
L
V
G
I
N
L
L
R
E
G
L
D
I
P
E
V
S
L
V
A
I
L
DADKE-------
G
F
L
R
S
E
R
S
L
I
Q
T
I
G
R
A
A
R
N
A
-
N
G
H
V
I
M
Y
A
-
D
T
I
T
K
S
M
E
I
A
I
Q
E
T
K
R
R
R
A
I
Q
E
E
Y
N
R
K
H
G
I
V
P
R
T
V
K
K
E
I
R
D
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
HHSearch
41.81
84%
-96
- C3 -
3FPN
-
?
B:
[157-250]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
-
V
S
L
R
V
G
M
E
I
E
R
N
A
L
L
R
R
L
V
D
I
Q
Y
D
R
N
D
I
D
F
R
R
G
T
F
R
V
R
G
D
V
V
E
I
F
P
A
S
-
R
D
E
H
C
I
R
V
E
F
F
G
D
E
I
E
R
I
R
-
E
V
D
A
L
T
G
E
V
L
G
E
R
E
H
V
A
I
F
P
A
S
H
F
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------