@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu06510: (2016-06-10 )
MKKFAVFASGNGSNFEAIVTRLKEENWDASAALLVCDKPQAKVIERAEAFHIPSFAFEPKSYENKAAFEQAIIEQLRLHEVELIALAGYMRLIGDTLLQAYGGKIINIHPSLLPAFPGIDAVGQAFRAGVKVAGITVHYVDEGMDTGPIIAQKAIEIDEHDTLETIEQRIHKLEHKWYPSVIKQLLGLNNRGEKA
Atome Classification :
(49 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MK
K
F
A
V
F
ASGNGS
N
F
E
A
I
V
T
R
L
K
EENWDA
S
A
A
L
L
V
CDK
P
Q
A
K
V
I
E
R
A
E
AFHIP
S
F
AFEPKSYE
N
K
A
A
F
E
Q
A
I
I
E
Q
L
R
LHE
V
E
L
I
A
L
A
G
Y
M
R
L
I
G
D
T
L
L
Q
A
YG
G
K
I
I
N
IHP
S
L
LPAFP
G
I
D
A
V
G
Q
A
F
RAG
V
K
V
A
G
I
T
V
H
Y
VDEGMDTG
P
I
I
A
Q
K
AIEIDEHD
T
L
E
T
I
E
Q
R
I
H
K
L
E
H
KW
Y
P
S
V
I
K
Q
L
LGLNNRGEKA
120
HHSearch
92.41
53%
-158
- C2 -
3P9X
6
?
A:
[3-192]
-
K
R
V
A
I
F
A
S
G
S
G
T
N
A
E
A
I
I
Q
S
Q
K
A
G
Q
L
P
C
E
V
A
L
L
I
T
D
K
P
G
A
K
V
V
E
R
V
K
V
H
E
I
P
V
C
A
L
D
P
K
T
Y
P
S
K
E
A
Y
E
I
E
V
V
Q
Q
L
K
E
K
Q
I
D
F
V
V
L
A
G
Y
M
R
L
V
G
P
T
L
L
G
A
Y
E
G
R
I
V
N
I
H
P
S
L
L
P
A
F
P
G
L
H
A
I
E
Q
A
I
R
A
N
V
K
V
T
G
V
T
I
H
Y
V
D
E
G
M
D
T
G
P
I
I
A
Q
E
A
V
S
I
E
E
E
D
T
L
E
T
L
T
T
K
I
Q
A
V
E
H
R
L
Y
P
A
T
L
H
K
L
L
S
K
A
E
N
----
2
PsiBlast_PDB
91.73
54%
-162
- C2 -
3P9X
6
?
A:
[3-188]
-
K
R
V
A
I
F
A
S
G
S
G
T
N
A
E
A
I
I
Q
S
Q
K
A
G
Q
L
P
C
E
V
A
L
L
I
T
D
K
P
G
A
K
V
V
E
R
V
K
V
H
E
I
P
V
C
A
L
D
P
K
T
Y
P
S
K
E
A
Y
E
I
E
V
V
Q
Q
L
K
E
K
Q
I
D
F
V
V
L
A
G
Y
M
R
L
V
G
P
T
L
L
G
A
Y
E
G
R
I
V
N
I
H
P
S
L
L
P
A
F
P
G
L
H
A
I
E
Q
A
I
R
A
N
V
K
V
T
G
V
T
I
H
Y
V
D
E
G
M
D
T
G
P
I
I
A
Q
E
A
V
S
I
E
E
E
D
T
L
E
T
L
T
T
K
I
Q
A
V
E
H
R
L
Y
P
A
T
L
H
K
L
L
S
--------
21
PsiBlast_CBE
90.88
54%
-163
- C2 -
3P9X
5
?
B:
[3-188]
-
K
R
V
A
I
F
A
S
G
S
G
T
N
A
E
A
I
I
Q
S
Q
K
A
G
Q
L
P
C
E
V
A
L
L
I
T
D
K
P
G
A
K
V
V
E
R
V
K
V
H
E
I
P
V
C
A
L
D
P
K
T
Y
P
S
K
E
A
Y
E
I
E
V
V
Q
Q
L
K
E
K
Q
I
D
F
V
V
L
A
G
Y
M
R
L
V
G
P
T
L
L
G
A
Y
E
G
R
I
V
N
I
H
P
S
L
L
P
A
F
P
G
L
H
A
I
E
Q
A
I
R
A
N
V
K
V
T
G
V
T
I
H
Y
V
D
E
G
M
D
T
G
P
I
I
A
Q
E
A
V
S
I
E
E
E
D
T
L
E
T
L
T
T
K
I
Q
A
V
E
H
R
L
Y
P
A
T
L
H
K
L
L
S
--------
122
HHSearch
88.13
47%
-163
- C2 -
4S1N
3
?
A:
[4-183]
M
K
K
I
A
V
F
A
S
G
N
G
S
N
F
Q
V
I
A
E
E
-------
F
P
V
E
F
V
F
S
D
H
R
D
A
Y
V
L
E
R
A
K
Q
L
G
V
L
S
Y
A
F
E
L
K
E
F
E
S
K
A
D
Y
E
A
A
L
V
E
L
L
E
E
H
Q
I
D
L
V
C
L
A
G
Y
M
K
I
V
G
P
T
L
L
S
A
Y
E
G
R
I
V
N
I
H
P
A
Y
L
P
E
F
P
G
A
H
G
I
E
D
A
W
N
A
G
V
G
Q
S
G
V
T
I
H
W
V
D
S
G
V
D
T
G
Q
V
I
K
Q
V
R
V
P
R
L
A
D
D
T
I
D
R
F
E
A
R
I
H
E
A
E
Y
R
L
Y
P
E
V
V
K
A
L
F
T
--------
3
PsiBlast_PDB
84.68
44%
-156
- C2 -
4S1N
3
?
A:
[5-182]
-
K
K
I
A
V
F
A
S
G
N
G
S
N
F
Q
V
I
A
E
E
F
P
V
E
-------
F
V
F
S
D
H
R
D
A
Y
V
L
E
R
A
K
Q
L
G
V
L
S
Y
A
F
E
L
K
E
F
E
S
K
A
D
Y
E
A
A
L
V
E
L
L
E
E
H
Q
I
D
L
V
C
L
A
G
Y
M
K
I
V
G
P
T
L
L
S
A
Y
E
G
R
I
V
N
I
H
P
A
Y
L
P
E
F
P
G
A
H
G
I
E
D
A
W
N
A
G
V
G
Q
S
G
V
T
I
H
W
V
D
S
G
V
D
T
G
Q
V
I
K
Q
V
R
V
P
R
L
A
D
D
T
I
D
R
F
E
A
R
I
H
E
A
E
Y
R
L
Y
P
E
V
V
K
A
L
F
---------
117
HHSearch
83.07
60%
-117
- C- -
3AV3
-
?
A:
[1-187]
M
K
R
L
A
V
F
A
S
G
S
G
T
N
F
Q
A
I
V
D
A
A
K
R
G
D
L
P
A
R
V
A
L
L
V
C
D
R
P
G
A
K
V
I
E
R
A
A
R
E
N
V
P
A
F
V
F
S
P
K
D
Y
P
S
K
A
A
F
E
S
E
I
L
R
E
L
K
G
R
Q
I
D
W
I
A
L
A
G
Y
M
R
L
I
G
P
T
L
L
S
A
Y
E
G
K
I
V
N
I
H
P
S
L
L
P
A
F
P
G
K
D
A
I
G
Q
A
Y
R
A
G
V
S
E
T
G
V
T
V
H
Y
V
D
E
G
-
D
T
G
P
V
I
A
Q
R
V
V
P
I
V
P
G
E
P
I
E
A
L
E
E
R
I
H
Q
V
E
H
E
L
Y
P
T
V
L
R
M
L
L
G
--------
31
PsiBlast_CBE
82.67
37%
-160
- C2 -
1RBM
4
B:
[2-182]
--
R
V
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
K
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
------------
118
HHSearch
82.62
36%
-163
- C2 -
4ZZ1
2
A:
[2-191]
-
A
R
V
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
-
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
L
V
A
S
G
T
V
Q
----
25
PsiBlast_CBE
82.51
37%
-161
- C2 -
1RBY
1
D:
[2-182]
--
R
V
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
K
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
------------
22
PsiBlast_CBE
82.44
37%
-163
- C2 -
1RC1
3
B:
[2-182]
--
R
V
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
K
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
------------
14
PsiBlast_PDB
82.39
37%
-161
- C2 -
1RC0
1
PUR2_HUMAN
A:
[2-182]
--
R
V
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
K
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
------------
24
PsiBlast_CBE
82.37
37%
-159
- C2 -
1RBZ
2
B:
[2-182]
--
R
V
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
K
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
------------
32
PsiBlast_CBE
82.23
37%
-164
- C2 -
1NJS
2
B:
[2-182]
--
R
V
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
K
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
------------
15
PsiBlast_PDB
82.03
37%
-162
- C2 -
1RC1
2
PUR2_HUMAN
A:
[2-182]
--
R
V
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
K
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
------------
29
PsiBlast_CBE
82.02
37%
-162
- C2 -
1RBQ
3
PUR2_HUMAN
C:
[2-182]
--
R
V
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
K
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
------------
28
PsiBlast_CBE
81.93
37%
-161
- C2 -
1RBQ
2
D:
[2-182]
--
R
V
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
K
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
------------
119
HHSearch
81.92
38%
-154
- C2 -
2YWR
5
?
A:
[1-191]
M
L
K
I
G
V
L
V
S
G
R
G
S
N
L
Q
A
I
I
D
A
I
E
S
G
K
V
N
A
S
I
E
L
V
I
S
D
N
P
K
A
Y
A
I
E
R
C
K
K
H
N
V
E
C
K
V
I
Q
R
K
E
F
P
S
K
K
E
F
E
E
R
M
A
L
E
L
K
K
K
G
V
E
L
V
V
L
A
G
F
M
R
I
L
S
H
N
F
L
K
Y
F
P
N
K
V
I
N
I
H
P
S
L
I
P
A
F
Q
G
L
H
A
Q
K
Q
A
V
E
F
G
V
K
F
S
G
C
T
V
H
I
V
D
E
S
V
D
A
G
P
V
I
V
Q
A
V
V
P
V
L
P
E
D
D
E
N
T
L
A
D
R
I
L
K
W
E
H
K
I
L
P
Q
T
V
Q
W
F
A
Q
D
R
I
I
----
27
PsiBlast_CBE
81.86
37%
-161
- C2 -
1RBY
2
PUR2_HUMAN
B:
[2-182]
--
R
V
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
K
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
------------
5
PsiBlast_PDB
81.85
37%
-162
- C2 -
4ZZ1
2
A:
[2-183]
-
A
R
V
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
-
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
------------
1
PsiBlast_PDB
81.75
58%
-116
- C- -
3AV3
-
?
A:
[2-187]
-
K
R
L
A
V
F
A
S
G
S
G
T
N
F
Q
A
I
V
D
A
A
K
R
G
D
L
P
A
R
V
A
L
L
V
C
D
R
P
G
A
K
V
I
E
R
A
A
R
E
N
V
P
A
F
V
F
S
P
K
D
Y
P
S
K
A
A
F
E
S
E
I
L
R
E
L
K
G
R
Q
I
D
W
I
A
L
A
G
Y
M
R
L
I
G
P
T
L
L
S
A
Y
E
G
K
I
V
N
I
H
P
S
L
L
P
A
F
P
G
K
D
A
I
G
Q
A
Y
R
A
G
V
S
E
T
G
V
T
V
H
Y
V
D
E
G
-
D
T
G
P
V
I
A
Q
R
V
V
P
I
V
P
G
E
P
I
E
A
L
E
E
R
I
H
Q
V
E
H
E
L
Y
P
T
V
L
R
M
L
L
G
--------
26
PsiBlast_CBE
81.54
37%
-163
- C2 -
1RBY
2
PUR2_HUMAN
C:
[2-182]
--
R
V
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
K
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
------------
126
HHSearch
81.53
37%
-182
- C2 -
3KCQ
1
?
A:
[8-193]
E
L
R
V
G
V
L
I
S
G
R
G
S
N
L
E
A
L
A
K
A
F
S
T
-
E
S
S
V
V
I
S
C
V
I
S
N
N
A
E
A
R
G
L
L
I
A
Q
S
Y
G
I
P
T
F
V
V
K
R
K
P
L
-----
D
I
E
H
I
S
T
V
L
R
E
H
D
V
D
L
V
C
L
A
G
F
M
S
I
L
P
E
K
F
V
T
D
W
H
H
K
I
I
N
I
H
P
S
L
L
P
S
F
K
G
L
N
A
Q
E
Q
A
Y
K
A
G
V
K
I
A
G
C
T
L
H
Y
V
Y
Q
E
L
D
A
G
P
I
I
M
Q
A
A
V
P
V
L
R
E
D
T
A
E
S
L
A
S
R
I
L
A
A
E
H
V
C
Y
P
K
G
V
K
L
I
A
Q
D
K
I
K
----
30
PsiBlast_CBE
81.48
37%
-162
- C2 -
1RBQ
3
PUR2_HUMAN
B:
[2-182]
--
R
V
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
K
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
------------
9
PsiBlast_PDB
81.32
37%
-159
- C2 -
1NJS
3
PUR2_HUMAN
A:
[2-182]
--
R
V
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
K
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
------------
6
PsiBlast_PDB
81.00
37%
-162
- C2 -
4ZZ2
2
A:
[2-183]
-
A
R
V
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
K
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
------------
11
PsiBlast_PDB
80.96
37%
-158
- C2 -
1RBQ
3
PUR2_HUMAN
A:
[2-182]
--
R
V
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
K
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
------------
23
PsiBlast_CBE
80.91
37%
-162
- C2 -
1RC0
1
B:
[2-182]
--
R
V
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
K
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
------------
12
PsiBlast_PDB
80.89
37%
-160
- C2 -
1RBY
2
PUR2_HUMAN
A:
[2-182]
--
R
V
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
K
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
------------
7
PsiBlast_PDB
80.64
37%
-155
- C2 -
4ZZ3
2
A:
[2-183]
-
A
R
V
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
K
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
------------
19
PsiBlast_PDB
80.54
37%
-162
- C2 -
1ZLY
2
A:
[2-182]
--
R
V
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
K
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
------------
10
PsiBlast_PDB
80.39
37%
-159
- C2 -
1RBM
3
PUR2_HUMAN
A:
[2-182]
--
R
V
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
K
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
------------
39
PsiBlast_CBE
79.84
37%
-178
- C2 -
3KCQ
1
?
C:
[10-185]
--
R
V
G
V
L
I
S
G
R
G
S
N
L
E
A
L
A
K
A
F
S
T
E
E
S
S
V
V
I
S
C
V
I
S
N
N
A
E
A
R
G
L
L
I
A
Q
S
Y
G
I
P
T
F
V
V
K
R
K
P
L
D
I
-----
E
H
I
S
T
V
L
R
E
H
D
V
D
L
V
C
L
A
G
F
M
S
I
L
P
E
K
F
V
T
D
W
H
H
K
I
I
N
I
H
P
S
L
L
P
S
F
K
G
L
N
A
Q
E
Q
A
Y
K
A
G
V
K
I
A
G
C
T
L
H
Y
V
Y
Q
E
L
D
A
G
P
I
I
M
Q
A
A
V
P
V
L
R
E
D
T
A
E
S
L
A
S
R
I
L
A
A
E
H
V
C
Y
P
K
G
V
K
------------
38
PsiBlast_CBE
79.68
37%
-176
- C2 -
3KCQ
1
?
D:
[10-185]
--
R
V
G
V
L
I
S
G
R
G
S
N
L
E
A
L
A
K
A
F
S
---
S
S
V
V
I
S
C
V
I
S
N
N
A
E
A
R
G
L
L
I
A
Q
S
Y
G
I
P
T
F
V
V
K
R
K
P
L
D
I
-----
E
H
I
S
T
V
L
R
E
H
D
V
D
L
V
C
L
A
G
F
M
S
I
L
P
E
K
F
V
T
D
W
H
H
K
I
I
N
I
H
P
S
L
L
P
S
F
K
G
L
N
A
Q
E
Q
A
Y
K
A
G
V
K
I
A
G
C
T
L
H
Y
V
Y
Q
E
L
D
A
G
P
I
I
M
Q
A
A
V
P
V
L
R
E
D
T
A
E
S
L
A
S
R
I
L
A
A
E
H
V
C
Y
P
K
G
V
K
------------
41
PsiBlast_CBE
79.31
37%
-182
- C2 -
3KCQ
1
?
A:
[10-185]
--
R
V
G
V
L
I
S
G
R
G
S
N
L
E
A
L
A
K
A
F
S
T
-
E
S
S
V
V
I
S
C
V
I
S
N
N
A
E
A
R
G
L
L
I
A
Q
S
Y
G
I
P
T
F
V
V
K
R
K
P
L
D
I
-----
E
H
I
S
T
V
L
R
E
H
D
V
D
L
V
C
L
A
G
F
M
S
I
L
P
E
K
F
V
T
D
W
H
H
K
I
I
N
I
H
P
S
L
L
P
S
F
K
G
L
N
A
Q
E
Q
A
Y
K
A
G
V
K
I
A
G
C
T
L
H
Y
V
Y
Q
E
L
D
A
G
P
I
I
M
Q
A
A
V
P
V
L
R
E
D
T
A
E
S
L
A
S
R
I
L
A
A
E
H
V
C
Y
P
K
G
V
K
------------
40
PsiBlast_CBE
79.19
37%
-175
- C2 -
3KCQ
1
?
B:
[10-185]
--
R
V
G
V
L
I
S
G
R
G
S
N
L
E
A
L
A
K
A
F
S
T
---
S
V
V
I
S
C
V
I
S
N
N
A
E
A
R
G
L
L
I
A
Q
S
Y
G
I
P
T
F
V
V
K
R
K
P
L
D
I
-----
E
H
I
S
T
V
L
R
E
H
D
V
D
L
V
C
L
A
G
F
M
S
I
L
P
E
K
F
V
T
D
W
H
H
K
I
I
N
I
H
P
S
L
L
P
S
F
K
G
L
N
A
Q
E
Q
A
Y
K
A
G
V
K
I
A
G
C
T
L
H
Y
V
Y
Q
E
L
D
A
G
P
I
I
M
Q
A
A
V
P
V
L
R
E
D
T
A
E
S
L
A
S
R
I
L
A
A
E
H
V
C
Y
P
K
G
V
K
------------
33
PsiBlast_CBE
78.90
37%
-155
- C2 -
1MEN
1
C:
[15-193]
----
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
K
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
------------
36
PsiBlast_CBE
78.57
37%
-160
- C2 -
1MEJ
1
C:
[15-193]
----
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
K
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
------------
35
PsiBlast_CBE
78.49
37%
-160
- C2 -
1MEN
1
PUR2_HUMAN
A:
[15-193]
----
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
K
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
------------
34
PsiBlast_CBE
77.90
37%
-159
- C2 -
1MEN
1
PUR2_HUMAN
B:
[15-193]
----
A
V
L
I
S
G
T
G
S
N
L
Q
A
L
I
D
S
T
R
E
P
N
S
S
A
Q
I
D
I
V
I
S
N
K
A
A
V
A
G
L
D
K
A
E
R
A
G
I
P
T
R
V
I
N
H
K
L
Y
K
N
R
V
E
F
D
S
A
I
D
L
V
L
E
E
F
S
I
D
I
V
C
L
A
G
F
M
R
I
L
S
G
P
F
V
Q
K
W
N
G
K
M
L
N
I
H
P
S
L
L
P
S
F
K
G
S
N
A
H
E
Q
A
L
E
T
G
V
T
V
T
G
C
T
V
H
F
V
A
E
D
V
D
A
G
Q
I
I
L
Q
E
A
V
P
V
K
R
G
D
T
V
A
T
L
S
E
R
V
K
L
A
E
H
K
I
F
P
A
A
L
Q
------------
63
PsiBlast_CBE
73.04
35%
-149
- C2 -
3DCJ
4
PUR3_MYCTU
A:
[14-185]
--
R
L
V
V
L
A
S
G
T
G
S
L
L
R
S
L
L
D
-
A
A
V
G
D
Y
P
A
R
V
V
A
V
G
V
D
R
-
E
C
R
A
A
E
I
A
A
E
A
S
V
P
V
F
T
V
R
L
A
D
H
P
S
R
D
A
W
D
V
A
I
T
A
A
T
A
A
H
E
P
D
L
V
V
S
A
G
F
M
R
I
L
G
P
Q
F
L
S
R
F
Y
G
R
T
L
N
T
H
P
A
L
L
P
A
F
P
G
T
H
G
V
A
D
A
L
A
Y
G
V
K
V
T
G
A
T
V
H
L
V
D
A
G
T
D
T
G
P
I
L
A
Q
Q
P
V
P
V
L
D
G
D
D
E
E
T
L
H
E
R
I
K
V
T
E
R
R
-------------------
62
PsiBlast_CBE
73.04
35%
-147
- C2 -
3DCJ
3
PUR3_MYCTU
B:
[14-185]
--
R
L
V
V
L
A
S
G
T
G
S
L
L
R
S
L
L
D
-
A
A
V
G
D
Y
P
A
R
V
V
A
V
G
V
D
R
-
E
C
R
A
A
E
I
A
A
E
A
S
V
P
V
F
T
V
R
L
A
D
H
P
S
R
D
A
W
D
V
A
I
T
A
A
T
A
A
H
E
P
D
L
V
V
S
A
G
F
M
R
I
L
G
P
Q
F
L
S
R
F
Y
G
R
T
L
N
T
H
P
A
L
L
P
A
F
P
G
T
H
G
V
A
D
A
L
A
Y
G
V
K
V
T
G
A
T
V
H
L
V
D
A
G
T
D
T
G
P
I
L
A
Q
Q
P
V
P
V
L
D
G
D
D
E
E
T
L
H
E
R
I
K
V
T
E
R
R
-------------------
54
PsiBlast_CBE
72.21
31%
-155
- C2 -
1CDE
2
PUR3_ECOLI
B:
[5-182]
-----
V
L
I
S
G
N
G
S
N
L
Q
A
I
I
D
A
C
K
T
N
K
I
K
G
T
V
R
A
V
F
S
N
K
A
D
A
F
G
L
E
R
A
R
Q
A
G
I
A
T
H
T
L
I
A
S
A
F
D
S
R
E
A
Y
D
R
E
L
I
H
E
I
D
M
Y
A
P
D
V
V
V
L
A
G
F
M
R
I
L
S
P
A
F
V
S
H
Y
A
G
R
L
L
N
I
H
P
S
L
L
P
K
Y
P
G
L
H
T
H
R
Q
A
L
E
N
G
D
E
E
H
G
T
S
V
H
F
V
T
D
E
L
D
G
G
P
V
I
L
Q
A
K
V
P
V
F
A
G
D
S
E
D
D
I
T
A
R
V
Q
T
Q
E
H
A
I
Y
P
L
V
I
S
------------
53
PsiBlast_CBE
71.93
31%
-155
- C2 -
1CDE
2
PUR3_ECOLI
C:
[5-182]
-----
V
L
I
S
G
N
G
S
N
L
Q
A
I
I
D
A
C
K
T
N
K
I
K
G
T
V
R
A
V
F
S
N
K
A
D
A
F
G
L
E
R
A
R
Q
A
G
I
A
T
H
T
L
I
A
S
A
F
D
S
R
E
A
Y
D
R
E
L
I
H
E
I
D
M
Y
A
P
D
V
V
V
L
A
G
F
M
R
I
L
S
P
A
F
V
S
H
Y
A
G
R
L
L
N
I
H
P
S
L
L
P
K
Y
P
G
L
H
T
H
R
Q
A
L
E
N
G
D
E
E
H
G
T
S
V
H
F
V
T
D
E
L
D
G
G
P
V
I
L
Q
A
K
V
P
V
F
A
G
D
S
E
D
D
I
T
A
R
V
Q
T
Q
E
H
A
I
Y
P
L
V
I
S
------------
55
PsiBlast_CBE
71.67
31%
-155
- C2 -
1CDE
2
PUR3_ECOLI
A:
[5-182]
-----
V
L
I
S
G
N
G
S
N
L
Q
A
I
I
D
A
C
K
T
N
K
I
K
G
T
V
R
A
V
F
S
N
K
A
D
A
F
G
L
E
R
A
R
Q
A
G
I
A
T
H
T
L
I
A
S
A
F
D
S
R
E
A
Y
D
R
E
L
I
H
E
I
D
M
Y
A
P
D
V
V
V
L
A
G
F
M
R
I
L
S
P
A
F
V
S
H
Y
A
G
R
L
L
N
I
H
P
S
L
L
P
K
Y
P
G
L
H
T
H
R
Q
A
L
E
N
G
D
E
E
H
G
T
S
V
H
F
V
T
D
E
L
D
G
G
P
V
I
L
Q
A
K
V
P
V
F
A
G
D
S
E
D
D
I
T
A
R
V
Q
T
Q
E
H
A
I
Y
P
L
V
I
S
------------
52
PsiBlast_CBE
71.43
31%
-155
* C2 *
1CDE
2
PUR3_ECOLI
D:
[5-182]
-----
V
L
I
S
G
N
G
S
N
L
Q
A
I
I
D
A
C
K
T
N
K
I
K
G
T
V
R
A
V
F
S
N
K
A
D
A
F
G
L
E
R
A
R
Q
A
G
I
A
T
H
T
L
I
A
S
A
F
D
S
R
E
A
Y
D
R
E
L
I
H
E
I
D
M
Y
A
P
D
V
V
V
L
A
G
F
M
R
I
L
S
P
A
F
V
S
H
Y
A
G
R
L
L
N
I
H
P
S
L
L
P
K
Y
P
G
L
H
T
H
R
Q
A
L
E
N
G
D
E
E
H
G
T
S
V
H
F
V
T
D
E
L
D
G
G
P
V
I
L
Q
A
K
V
P
V
F
A
G
D
S
E
D
D
I
T
A
R
V
Q
T
Q
E
H
A
I
Y
P
L
V
I
S
------------
59
PsiBlast_CBE
70.76
31%
-150
- C2 -
1C2T
2
PUR3_ECOLI
A:
[5-182]
-----
V
L
I
S
G
N
G
S
N
L
Q
A
I
I
D
A
C
K
T
N
K
I
K
G
T
V
R
A
V
F
S
N
K
A
D
A
F
G
L
E
R
A
R
Q
A
G
I
A
T
H
T
L
I
A
S
A
F
D
S
R
E
A
Y
D
R
E
L
I
H
E
I
D
M
Y
A
P
D
V
V
V
L
A
G
F
M
R
I
L
S
P
A
F
V
S
H
Y
A
G
R
L
L
N
I
H
P
S
L
L
P
K
Y
P
G
L
H
T
H
R
Q
A
L
E
N
G
D
E
E
H
G
T
S
V
H
F
V
T
D
E
L
D
G
G
P
V
I
L
Q
A
K
V
P
V
F
A
G
D
S
E
D
D
I
T
A
R
V
Q
T
Q
E
H
A
I
Y
P
L
V
I
S
------------
61
PsiBlast_CBE
70.60
31%
-150
- C2 -
1C3E
2
PUR3_ECOLI
A:
[5-182]
-----
V
L
I
S
G
N
G
S
N
L
Q
A
I
I
D
A
C
K
T
N
K
I
K
G
T
V
R
A
V
F
S
N
K
A
D
A
F
G
L
E
R
A
R
Q
A
G
I
A
T
H
T
L
I
A
S
A
F
D
S
R
E
A
Y
D
R
E
L
I
H
E
I
D
M
Y
A
P
D
V
V
V
L
A
G
F
M
R
I
L
S
P
A
F
V
S
H
Y
A
G
R
L
L
N
I
H
P
S
L
L
P
K
Y
P
G
L
H
T
H
R
Q
A
L
E
N
G
D
E
E
H
G
T
S
V
H
F
V
T
D
E
L
D
G
G
P
V
I
L
Q
A
K
V
P
V
F
A
G
D
S
E
D
D
I
T
A
R
V
Q
T
Q
E
H
A
I
Y
P
L
V
I
S
------------
58
PsiBlast_CBE
69.58
31%
-150
- C2 -
1C2T
2
PUR3_ECOLI
B:
[5-182]
-----
V
L
I
S
G
N
G
S
N
L
Q
A
I
I
D
A
C
K
T
N
K
I
K
G
T
V
R
A
V
F
S
N
K
A
D
A
F
G
L
E
R
A
R
Q
A
G
I
A
T
H
T
L
I
A
S
A
F
D
S
R
E
A
Y
D
R
E
L
I
H
E
I
D
M
Y
A
P
D
V
V
V
L
A
G
F
M
R
I
L
S
P
A
F
V
S
H
Y
A
G
R
L
L
N
I
H
P
S
L
L
P
K
Y
P
G
L
H
T
H
R
Q
A
L
E
N
G
D
E
E
H
G
T
S
V
H
F
V
T
D
E
L
D
G
G
P
V
I
L
Q
A
K
V
P
V
F
A
G
D
S
E
D
D
I
T
A
R
V
Q
T
Q
E
H
A
I
Y
P
L
V
I
S
------------
60
PsiBlast_CBE
69.49
31%
-150
- C2 -
1C3E
2
PUR3_ECOLI
B:
[5-182]
-----
V
L
I
S
G
N
G
S
N
L
Q
A
I
I
D
A
C
K
T
N
K
I
K
G
T
V
R
A
V
F
S
N
K
A
D
A
F
G
L
E
R
A
R
Q
A
G
I
A
T
H
T
L
I
A
S
A
F
D
S
R
E
A
Y
D
R
E
L
I
H
E
I
D
M
Y
A
P
D
V
V
V
L
A
G
F
M
R
I
L
S
P
A
F
V
S
H
Y
A
G
R
L
L
N
I
H
P
S
L
L
P
K
Y
P
G
L
H
T
H
R
Q
A
L
E
N
G
D
E
E
H
G
T
S
V
H
F
V
T
D
E
L
D
G
G
P
V
I
L
Q
A
K
V
P
V
F
A
G
D
S
E
D
D
I
T
A
R
V
Q
T
Q
E
H
A
I
Y
P
L
V
I
S
------------