@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu40590: (2016-08-07 )
MESHIYRIIKNKLTIIIFTIIILIPCVDISLLLMTNTEYHPAYAFFLSGTSVGHASQMILLWFLPLYFLLLCADDSIQDYKTGYHYILISKVGRKKYCLEKIFTSFIISFLTMFLSLILNFLLVQVFFFKGTFKNDLDQIKFPDNSLYTFSMAHPYIAIVLFSIICCIMSGFVGALGSSLSLLFRDKKYAYPASFFIWFVLILKNKSLMFLFQPFTEYGYNVLLPILCLSIFIFLIIISSIVLYEAKYNEN
Atome Classification :
(20 SA)
---------------------------.......--..10........20----.--.----------..----.....30........-------------40.......---.50...---------.....60....---.....70..----..---....80..----......90.-.----.--.....100-----........110.......---------120--.------.---.......130..--....----.140.......150.....----..160.---.----.....170........180.......190....---.---..200-----------.......210....---...220...-..--------..230..-....------------------.240.......250--------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------ME
S
H
I
Y
R
--
I
I
KNK
L
T
I
I
I
F
T
I
-----
I
--
I
----------
L
I----PCV
D
I
S
L
L
L
M
TNTEY-------------
H
P
A
Y
A
F
F
LS---GTSVG
H
---------
A
S
Q
M
I
L
-
L
W
F
L
---
P
L
Y
F
L
L
L
CA----DD---S
I
Q
D
YKTG----
Y
H
Y
I
L
I
SKV-G----
R
--
K
K
Y
C
L
E
K
------
I
F
T
S
F
I
I
S
F
L
T
M
F
L
S
L
I
L
---------
N
----
F
------
L
---
L
V
Q
V
F
F
FKGTFK--ND
L
D
----QIKFPDN
S
L
Y
T
F
SMA
H
P
Y
I
----
A
I
V
L
F
S
---
I
----
I
C
C
I
M
S
-
G
F
V
G
A
L
G
S
S
L
S
L
L
FRDKKYAY
P
A
S
F
F
---
I
---
W
F
V
L
I
-----------LKNK
S
L
M
F
L
FQ
P
F
T
---EY
G
Y
N
V
L
L
P
-
I
L
--------
C
L
S
I
F
I
F
-
L
I
I
I
------------------
S
S
I
V
L
Y
E
A
KYNEN---------------------------------------------------
15
Fugue
70.77
19%
-92
* C11 *
4CIJ
-
?
A:
[1-267]
---------------------------
M
S
G
-------
L
K
P
C
V
D
W
L
Q
V
T
F
-----
K
--
T
GQDS------
V
K
----
K
C
V
E
K
L
E
K
V
F
E
I
L
G
L
-------------
N
E
A
E
F
L
P
L
K
---
N
G
K
Y
G
Y
---------
K
Q
G
V
A
F
-
Q
G
N
P
---
V
L
A
V
Y
Y
D
G
A
----
D
D
---
M
-----------
G
I
H
V
E
M
T
G
Q
-
G
----
C
--
R
L
F
E
L
H
---------
T
S
--
I
N
W
Y
E
L
F
Y
R
L
V
Y
---------
E
----
Y
E
V
N
IT
R
L
---
D
V
A
V
D
D
F
K
G
Y
F
K
--
I
N
T
L
----
V
K
K
L
K
D
D
E
V
T
S
R
F
K
K
A
R
H
I
----
E
N
I
V
I
E
GGE
T
----
I
G
H
T
L
---
Y
F
G
A
P
S
S
D
I
Q
V
R
F
Y
E
K
N
V
Q
M
G
M
D
I
D
---
V
---
W
-----------------
N
R
T
E
I
Q
L
R
D
D
R
A
---
H
V
V
A
Q
I
I
A
D
D
V
L
--------
P
L
G
E
I
V
A
-
G
L
L
R
------------------
N
Y
I
Q
F
R
T
R
K
A
T
D
K
NKKRWPLA
R
F
W
L
N
F
L
G
D
V
QPLRIAKQM------------------------
20
Fugue
62.46
13%
-159
- C8 -
4MUO
-
YBIB_ECOLI
A:
[1-320]
MD
Y
R
K
I
I
K
E
IGRGKNH
A
R
D
L
D
R
D
T
A
R
G
L
Y
A
H
M
L
N
GE
V
P
D
L
E
L
G
G
V
L
I
A
L
-----
R
--
I
K
GEG
E
A
E
M
L
G
F
Y
----
E
A
M
Q
N
H
T
I
K
L
T
P
P
A
G
-------------
K
P
M
P
I
V
I
P
S
YNG
A
R
K
Q
A
N
---------
L
T
P
L
L
A
-
I
L
L
H
---
K
L
G
F
P
V
V
V
H
G
V
SE
D
P
---
T
R
V
L
T
E
T
I
----
F
E
L
M
G
I
T
P
T
-
L
----
H
--
G
G
Q
A
Q
A
K
------
L
D
E
H
Q
P
V
F
M
P
V
G
A
F
C
P
P
L
---------
E
----
K
------
Q
---
L
A
M
R
W
R
M
G
------------------
V
R
N
S
A
H
T
L
A
K
L
A
T
P
F
AEGE
A
L
R
L
S
S
---
V
SHPE
Y
I
G
R
V
A
-
K
F
F
S
D
I
G
G
R
A
L
L
M
H
G
T
E
G
E
V
Y
A
N
P
Q
R
---
C
---
P
Q
I
N
L
-----------
I
D
R
E
G
M
R
V
L
Y
E
K
Q
A
KD
P
E
T
T
A
Q
W
I
E
R
-
C
L
A
GSEPIP
E
S
L
K
I
Q
M
A
-
C
C
L
V
A
T
GEA-------------
A
T
I
S
D
G
L
A
R
V
N
Q
A
F--------------------------------------------------
17
Fugue
52.55
12%
-42
- C7 -
1SVB
1
?
?:
[1-302]
----------------------S
R
C
T
H
L
E
N
R
D
F
V
--
T
G
T
Q
G
T
T
R
V
T
L
V
L
ELG
G
C
V
--
T
----------
I
T
A
E
GK
P
S
M
D
V
W
L
D
A
I
Y
Q
E
N
P
-------------
A
K
T
R
E
Y
C
L
H
---
A
K
L
S
D
T
---------
K
V
A
A
----------------
R
C
P
----
T
M
G
P
A
T
L
A
E
E
H
Q
G
----
G
T
V
C
K
R
D
Q
S
-
D
----
R
G
W
G
N
H
C
G
L
F
G
K
G
S
I
V
A
C
V
K
A
A
C
E
A
K
K
K
A
T
G
H
V
Y
---------
D
ANK
I
V
------
Y
---
T
V
K
V
E
P
H
T
G
D
Y
V
--
A
A
N
E
----
T
H
S
G
R
K
T
A
S
F
T
I
S
S
E
K
T
I
L
T
MG-
E
Y
G
D
V
S
---
L
----
L
C
R
V
A
S
-
G
V
--
D
L
A
Q
T
V
I
L
E
L
D
K
T
V
E
H
L
P
T
A
W
Q
---
V
H
R
D
W
F
N
D
L
A
L
P
W
K
H
EGAQN
W
N
N
A
E
R
L
V
E
F
G
A
P
H
---
A
V
K
M
D
V
Y
N
L
-
G
D
--------
Q
T
G
V
L
L
K
A
L
A
G
V
------------------
P
V
A
H
I
E
G
T
K
Y
H
L
K
S
G
H
V
T
C
E
V
G
LEK
L
K
M
K
GL---------------------------------
22
Fugue
47.19
14%
-134
- C10 -
1W5C
9
PSBD_THEEB
D:
[1-350]
-------MTIAIG
R
A
P
A
E
RGWF
D
I
L
D
D
W
L
K
R
D
R
F
--
V
F
V
G
W
S
G
I
L
L
F
P
C
-----
A
--
Y
----------
L
A
----
L
G
G
W
L
T
G
T
T
F
V
T
S
W
Y
THG
L
A
S
S
YLEGCN
F
L
T
V
A
V
S
T
P
---
A
N
S
M
G
H
SLLLLWGPE
A
Q
G
D
F
T
-
R
W
C
Q
L
GG
L
W
T
F
I
A
L
H
G
----
A
F
---
G
L
I
G
F
M
-
L
----
R
Q
F
E
I
A
R
L
V
-
G
----
V
--
R
P
Y
N
A
I
A
-------
F
S
A
P
I
A
V
F
V
S
V
F
L
I
Y
P
L
G
QSSWFFAP
S
----
F
------
G
---
V
A
A
I
F
R
F
L
L
F
F
Q
--
G
F
H
N
-------
W
T
L
N
P
F
H
M
M
G
V
A
G
V
L
G
----
G
A
L
L
C
A
---
I
----
H
G
A
T
V
E
-
N
T
L
F
Q
D
G
E
G
A
S
T
F
R
A
F
N
P
T
Q
A
E
E
T
Y
S
---
M
---
V
T
A
N
R
-----------
F
W
S
Q
I
F
G
I
A
F
S
N
-
K
---
R
W
L
H
F
F
M
L
F
-
V
P
--------
V
T
G
L
W
M
S
-
A
I
G
V
------------------
V
G
L
A
L
N
L
R
S
Y
D
F
I
SQ
E
I
R
A
A
E
D
P
EFETF
Y
T
K
N
L
L
L
N
E
G
I
R
A
W
M
APQDQPH
E
N
F
V
F
P
EEVLPRGN
21
Fugue
45.61
12%
-85
* C10 *
3EUH
-
MUKE_ECOLI
C:
[10-215]
---------------------------
M
P
V
K
L
A
Q
--
A
L
A
N
P
L
---------------------------
F
----
P
A
L
D
S
A
L
R
----
S
G
R
-------------
H
I
G
L
D
E
L
D
N
---
H
A
F
L
M
D
---------
F
Q
E
Y
L
E
-
E
F
Y
A
---
R
Y
N
V
E
L
I
R
A
----
P
E
----------
G
----
F
F
Y
L
R
P
R
S
T
-
T
L
I
P
R
S
--
V
L
S
E
L
D
M
------
M
V
G
K
I
L
C
Y
L
Y
L
S
P
E
R
L
A
N
---------
E
----
G
------
I
---
F
T
Q
Q
E
L
Y
D
E
L
L
T
L
A
D
E
A
K
----
L
L
K
L
V
N
N
R
S
T
G
S
D
V
D
R
Q
K
L
----
Q
E
K
V
R
S
---
S
----
L
N
R
L
R
R
L
G
M
V
W
F
M
G
H
D
------
S
S
K
F
R
I
T
E
S
V
F
---
R
---
F
G
A
D
V
-----------
R
A
G
D
D
P
R
E
A
Q
R
R
L
I
---
R
D
G
E
A
M
P
I
E
-
N
-------------------------------------------------------------------------------------------------------
14
Fugue
45.58
11%
-64
- C9 -
1QXM
5
HA33_CLOBO
A:
[18-300]
-----------------------------
T
N
A
N
D
--
L
R
N
N
E
V
F
F
I
S
P
S
N
-----
N
TN
K
----------
V
L
----
D
K
I
S
Q
S
E
V
K
L
W
N
K
L
S
-------------
G
A
N
Q
K
W
R
L
I
---
Y
D
T
N
K
Q
---------
A
Y
K
I
K
V
-
M
D
N
T
---
S
L
I
L
T
W
N
A
P
----
L
S
---
S
V
S
V
K
T
D
T
NGDN
Q
Y
W
Y
L
L
Q
N
Y
-
I
----
S
--
R
N
V
I
I
R
N
------
Y
M
N
P
N
L
V
L
Q
Y
N
I
D
D
T
L
M
V
---------
S
----
T
------
Q
TSS
S
N
Q
F
F
K
F
S
N
C
I
Y
--
E
A
L
N
N
R
N
C
K
L
Q
T
Q
L
N
S
D
R
F
L
S
K
N
L
N
S
Q
----
I
I
V
L
W
Q
----------------
W
F
D
S
S
R
Q
K
W
I
I
E
Y
N
E
T
K
S
A
Y
T
L
K
C
Q
ENN
R
---
Y
L
T
W
I
-----------
Q
N
S
N
N
Y
V
E
T
Y
Q
S
T
D
---
S
L
I
Q
Y
W
N
I
N
-
Y
L
--------
D
N
D
A
S
K
Y
-
I
L
Y
N
LQDTNRVLDVYNSQIANG
T
H
V
I
V
D
S
Y
H
G
N
T
N
Q
Q
W
I
I
N
L
I-------------------------------------------
3
PsiBlast_PDB
36.15
44%
-227
- C12 -
3J9D
-
?
A:
[715-748]
---------------------------------------------------------------------------------------
E
F
-------------
F
P
T
Y
G
G
L
L
N
---
G
L
N
S
A
T
---------
V
V
Q
N
I
M
Y
L
N
F
L
---
P
L
Y
F
L
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
26.51
31%
-43
- C13 -
4PKF
-
?
C:
[20-46]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
Y
E
A
G
----
K
A
D
C
V
R
E
K
E
D
E
----
K
--
G
K
Y
W
L
S
K
------
P
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
26.36
13%
-
- C4 -
4XTR
-
?
G:
[15-19]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
--
W
R
V
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
25.38
24%
-94
* C13 *
4LQZ
-
?
A:
[45-73]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
E
K
G
----
T
A
K
Y
F
I
D
K
V
-
G
----
S
--
K
R
Y
L
F
I
E
------
Y
I
P
D
N
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
23.19
50%
-83
- C12 -
5E9T
-
?
B:
[200-225]
--------------------------------------------------------------------------------------------------------
A
Y
S
F
L
V
S
---
H
S
L
T
G
R
---------
A
G
Q
D
I
L
-
F
W
Q
E
---
P
L
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
23.05
50%
-89
* C12 *
5E9U
-
?
B:
[200-225]
--------------------------------------------------------------------------------------------------------
A
Y
S
F
L
V
S
---
H
S
L
T
G
R
---------
A
G
Q
D
I
L
-
F
W
Q
E
---
P
L
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
22.56
14%
-
- C6 -
2MOF
-
LAMP2_HUMAN
A:
[395-401]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Y
F
I
G
L
K
-------------------------------------------------------
5
HHSearch
20.99
0%
-75
- C3 -
2LR1
-
B:
[4-14]
-------------------------------
L
K
K
--
A
L
R
R
H
R
F
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
19.93
31%
-32
- C11 -
2PJV
-
A:
[1-24]
-------------------------------------------------------------------------------------
A
V
G
I
-------------
G
A
L
F
L
G
F
L
G
AA-
G
S
T
V
G
A
---------
A
S
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
16.21
20%
-41
- C11 -
2LQ0
-
?
A:
[1-25]
------------------------------------------------------------------------------------
Q
R
S
N
F
-------------
H
P
L
A
A
S
F
I
V
---
R
C
A
F
E
H
---------
S
R
R
F
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
14.60
10%
-86
- C1 -
1YTR
-
PLNA_LACPL
A:
[15-24]
-----------------------------
K
Q
V
K
K
--
L
F
K
K
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
11.10
40%
-
- C2 -
2MFR
-
A:
[35-44]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
I
Y
L
F
L
R
K
R
------------------------------------------------------
12
HHSearch
5.54
9%
-
- C5 -
2KET
-
A:
[7-17]
----------------------------
R
K
K
F
K
K
--
L
F
K
K
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
0.45
6%
76
- C12 -
4B19
-
?
A:
[13-30]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
G
-
C
A
I
A
------------------
F
F
S
Y
W
L
S
R
R
N
T
K
----------------------------------------------------