@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0120: (2016-03-12 )
MNHIHEHLKLVPVDKIDLHETFEPLRLEKTKSSIEADDFIRHPILVTAMQHGRYMVIDGVHRYTSLKALGCKKVPVQEIHETQYSISTWQHKVPFGVWWETLQQEHRLPWTTETRQEAPFITMCHGDTEQYLYTKDLGEAHFQVWEKVVASYSGCCSVERIAQGTYPCLSQQDVLMKYQPLSYKEIEAVVHKGETVPAGVTRFNISGRCLNLQVPLALLKQDDDVEQLRNWKQFLADKFANMRCYTEKVYLVEQ
Atome Classification :
(20 SA)
--------------------------.........10.......--.20----.-.-------------------.......30---.......---.----.40.-.......50---.----........60........70.---.--------------------------......80----........90.--.......100.....------------..110---......--..120..--.....130.......140........--150.--......160.-...---------...170------.........180.----......190.......200....-...-210--.......220.......230.......240.......250..-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------MN
H
I
H
E
H
L
KLVPVDKI
D
L
--
H
E-----T-F-------------------E
P
L
R
L
E
K
T----KSSIE
A
D
---
D
----
F
IRH-
P
I
L
V
T
A
M
Q----H----G
R
Y
M
V
I
DGV
H
R
Y
T
S
L
KALGCK---K--------------------------V
P
V
Q
E
I
H
E----TQYSISTWQHK--V
P
F
G
V
W
W
E
T
L
Q
Q
EHR------------LPWT----TETRQE--A
P
F
I
T
M
C--HGDTE
Q
Y
L
Y
T
K
DL
G
E
A
-
H
F
Q
V
W
E
K
V
V
--
A
SYS--GC
C
S
V
E
R
I
AQ-GTY---------PCLS--------QQD
V
L
M
KYQPL
S
Y
----
K
E
I
E
A
V
V
HKGETVPA
G
V
T
R
FNIS-
G
R
C
-
L
N
L
--QV
P
L
A
L
LKQDD
D
V
E
Q
L
R
N
W
K
Q
F
L
A
D
K
FAN
M
R
C
Y
T
E
K
V
Y
L
VEQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
79.79
21%
-39
- C2 -
4ZOX
-
SQT1_YEAST
A:
[3-381]
---------------------MSNNS
L
T
Y
F
D
K
H
T
D
--
S
V
F
A
I
G
H
--
H
P
-----
N
-
L
P
L
V
C
T
G
GGDN
L
A
H
L
W
T
SHS
Q
P
P
K
F
A
G
T
L
T
GY
G
E
S
V
I
S
C
---
S
----
F
T
S
E
G
G
F
L
V
T
A
D
M
----
S
----
G
K
V
L
V
H
M
G
Q
K
G
G
A
Q
W
K
L
A
S
Q
M
---
Q
EVEEIV
W
L
K
T
HPTIAR
T
F
A
F
G
A
TDG
S
V
W
C
Y
Q
I
N
E
QDG
S
L
E
Q
L
M
S
G
F
V
H
Q
QD
C
S
M
G
E
F
I
N
T
D
K
G
E
N
T
L
E
L
V
T
C
S
LDS
T
I
V
A
W
N
----
C
F
T
G
Q
Q
--
L
F
K
I
T
Q
A
EI
K
G
L
E
A
P
W
I
S
L
S
L
A
P
E
T
-
L
T
K
G
N
S
G
V
V
--
A
C
G
S
NN
G
L
L
A
V
I
N
C
N
N
G
G
A
I
---------
L
H
L
S
T
V
I
E
L
K
PE
Q
D
E
L
D
A
S
I
E
S
I
S
W
S
SKF
S
L
M
A
I
G
L
V
C
G
E
I
L
L
Y
D
T
S
A
W
R
V
R
-
H
K
F
V
L
E
D
--
S
V
T
K
L
M
F
D
N
D
D
L
F
A
S
C
I
N
G
K
V
Y
Q
F
N
----
A
R
T
G
Q
E
K
F
V
C
V
G
H
NMGVL
D
F
I
L
L
H
PVANTG
T
E
Q
K
R
K
V
I
T
A
G
DEG
V
S
L
V
F
E
V
P
N-------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
78.52
17%
-43
- C4 -
1VZ0
2
SP0J_THET2
A:
[23-208]
----------------------------
V
V
R
L
P
L
A
S
I
R
P
N
P
R
Q
P
--
R
K
-----
R
-
F
-------------------
A
E
E
S
L
K
E
L
----
A
D
S
I
R
E
K
---
G
-----
L
L
Q
-
P
L
L
V
R
P
Q
-----
G
----
D
G
Y
E
L
V
A
G
E
R
R
Y
R
A
A
L
M
A
G
L
Q
---
E
--------------------------
V
P
-------------------------------
A
V
V
K
D
L
T
------------
D
R
E
A
----
L
E
L
A
L
V
--
E
N
L
Q
R
E
D
--
L
S
P
V
E
E
A
R
G
Y
Q
A
L
L
E
M
-
G
L
------------------
T
Q
E
E
V
A
R
-
R
V
G
---------
K
A
R
S
--------
T
V
A
N
A
L
R
L
L
Q
L
P
-----
P
E
A
L
E
A
L
E
R
G
E
-----------------
I
T
A
--
G
H
A
R
A
L
L
M
L
E
-
P
E
D
R
L
W
G
L
K
E
I
L
E
K
G
L
S
V
R
Q
A
E
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
75.25
18%
-41
- C4 -
1XW3
1
SRXN1_HUMAN
A:
[11-99]
------------------------------
I
A
A
V
H
N
V
P
L
S
V
L
I
R
P
L
P
S
-----
V
-
L
-------------------
D
P
A
K
V
Q
S
L
----
V
D
T
I
R
E
D
---
P
----
D
S
V
P
-
P
I
D
V
L
W
I
K
----
G
AQG
G
D
Y
F
Y
S
F
G
G
C
H
R
Y
A
A
Y
Q
Q
L
Q
R
E
---
T
--------------------------
I
P
A
K
L
V
Q
S
----
T
L
S
D
L
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
71.99
19%
-37
- C4 -
1YZS
-
SRXN1_HUMAN
A:
[39-122]
-------------------------------
A
A
V
H
N
V
P
L
S
V
L
I
R
P
L
P
S
-----
V
-
L
-------------------
D
P
A
K
V
Q
S
L
----
V
D
T
I
R
E
D
---
P
----
D
S
V
P
-
P
I
D
V
L
W
I
K
----
G
AQGG
D
Y
F
Y
S
F
G
G
C
H
R
Y
A
A
Y
Q
Q
L
Q
R
E
---
T
--------------------------
I
P
A
K
L
V
Q
S
----
T
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
70.37
23%
-40
* C4 *
1VZ0
2
SP0J_THET2
A:
[23-100]
---------------------------------
V
V
R
L
P
L
A
S
I
R
P
--
N
P
RQ
P
R
K
R
-
F
-------------------
A
E
E
S
L
K
E
L
----
A
D
S
I
R
E
K
---
G
----
L
L
-
Q
-
P
L
L
V
R
P
Q
-----
G
----
D
G
Y
E
L
V
A
G
E
R
R
Y
R
A
A
L
M
A
G
L
Q
---
E
--------------------------
V
P
A
V
V
K
D
L
----
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
69.09
15%
-48
- C4 -
1XW3
1
SRXN1_HUMAN
A:
[1-110]
--------------------GPHM
S
I
H
S
G
R
I
A
A
V
H
N
V
P
L
S
V
L
I
R
--
P
L
P
S
---
V
-
L
-------------------
D
P
A
K
V
Q
S
L
----
V
D
T
I
R
E
D
---
P
----
D
S
V
P
-
P
I
D
V
L
W
I
K
G
AQG
G
----
D
Y
F
Y
S
F
G
G
C
H
R
Y
A
A
Y
Q
Q
L
Q
R
E
---
T
--------------------------
I
P
A
K
L
V
Q
S
----
T
L
S
D
L
R
V
Y
L
G
A
--
S
T
P
D
L
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
67.73
18%
-59
- C4 -
2HWJ
-
?
A:
[6-89]
------------------------------
E
P
R
L
S
R
I
A
I
D
K
L
R
P
--
T
Q
-----
I
A
V
-------------------
G
F
R
E
V
E
L
K
----
R
K
E
W
R
E
T
---
R
DFLG
N
H
I
V
-
P
V
V
A
G
P
------
K
----
D
R
A
Y
L
I
D
H
H
H
L
V
L
A
L
S
K
E
G
V
E
---
H
--------------------------
V
L
T
S
E
V
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
64.65
18%
-33
- C1 -
3J9O
-
?
B:
[79-505]
-----------------------------
V
I
D
K
L
I
D
L
Q
V
N
S
I
I
S
--
N
D
-----
E
-
F
-------------------
R
A
L
E
Q
E
W
L
----
K
V
Q
E
V
C
Q
EDY
D
----
N
V
E
V
-
S
I
L
D
V
K
K
E
----
E
----
L
Q
Y
D
F
E
R
N
L
Y
D
I
S
S
S
D
F
F
--
K
---
K
--------------------------
V
Y
V
S
E
F
D
------
Q
Y
G
G
E
P
Y
G
A
I
--
L
G
L
Y
N
F
E
N
T
T
N
D
I
I
W
------------
L
T
G
M
----
G
M
V
A
K
N
S
H
A
P
F
I
A
S
I
--
D
K
S
---
F
F
G
V
K
D
L
S
E
I
T
H
I
K
S
F
E
A
L
L
E
H
P
R
Y
K
--
E
W
N
D
F
R
N
L
D
V
-
A
A
Y
---------
I
G
L
T
--------
V
G
D
F
M
L
R
-
Q
P
Y
N
P
----
E
N
-
N
P
V
Q
Y
K
L
M
E
G
F
N
E
F
V
D
Y
D
K
N
-
E
S
Y
-
L
W
G
--
P
A
S
I
H
L
V
K
N
M
M
R
S
Y
D
K
T
R
W
F
Q
Y
I
R
G
V
E
S
G
--
G
Y
V
K
N
L
V
A
C
V
Y
D
NKGIL
E
T
K
S
PLNVLFA
D
Y
M
E
L
S
L
A
N
I
GLIPFVSEKGTS
N
A
C
F
FSVNSAKKVEEFVD
G
F
D
S
A
N
S
R
L
I
A
N
L
S
Y
T
M
C
I
S
R
I
S
H
Y
I
K
C
VIRDKIGSIVD
V
E
S
I
Q
K
I
L
S
D
W
I
SEFVTTVYQPTPLEMARYPFR
N
V
S
I
E
V
K
T
I
P
GKPG
W
Y
S
C
K
I
N
V
I
P
HIQFE
G
M
N
T
T
M
T
IDTRLEPELFGTNN
26
Fugue
61.63
11%
-18
- C3 -
2OI2
2
?
A:
[4-292]
K
V
G
V
G
Q
A
H
S
K
I
I
LIG
E
H
A
V
V
Y
G
Y
P
A
I
S
L
P
L
L
E
V
E
V
T
C
K
V
V
P
A
E
S
--
P
W
-----
R
-
L
-------------------
Y
E
E
D
T
L
S
M
----
A
V
Y
A
S
L
E
---
Y
----
L
N
I
T
-
E
A
C
I
R
C
E
I
D---
E
----
K
R
G
M
G
S
S
A
A
I
S
I
A
A
I
R
A
V
F
D
Y
Y
Q
A
D
--------------------------
L
P
H
D
V
L
E
I
----
L
V
N
R
A
E
M
I
A
H
M
--
N
P
S
G
L
D
A
K
T
C
L
S
D
Q
P
------------
I
R
F
I
K
N
V
G
F
T
E
L
E
M
--
D
L
S
A
Y
L
V
--
I
A
D
T
G
V
Y
G
H
T
R
E
A
I
Q
V
-
V
Q
N
K
G
K
D
A
L
--
P
F
L
H
--
A
L
G
E
L
T
Q
Q
A
E
-
I
A
I
S
Q
KD
A
E
G
L
G
Q
I
L
S
--------
Q
A
H
L
H
L
K
E
I
G
V
S
S
----
L
E
A
D
S
L
V
E
T
A
L
S
H
G
A
L
G
A
K
M
S
G
G
-
G
----
L
G
--
G
C
I
I
A
L
V
T
---
N
L
T
H
A
Q
E
L
A
E
R
L
E
E
K
G
A
V
Q
T
W
I
E
S
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
50.26
36%
71
- C4 -
3VI3
1
ITB1_HUMAN
B:
[186-228]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
C
T
S
--------
E
Q
N
C
T
T
---
P
F
S
Y
----
K
N
V
L
S
L
T
N
K
G
E
V
F
N
E
L
V
G
K
Q
R
I
S
-
G
----
N
L
--
D
S
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
49.37
36%
76
- C4 -
3VI4
2
ITB1_HUMAN
B:
[186-228]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
C
T
S
--------
E
Q
N
C
T
T
---
P
F
S
Y
----
K
N
V
L
S
L
T
N
K
G
E
V
F
N
E
L
V
G
K
Q
R
I
S
-
G
----
N
L
--
D
S
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
49.34
36%
66
- C4 -
4WJK
2
ITB1_HUMAN
B:
[186-228]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
C
T
S
--------
E
Q
N
C
T
T
---
P
F
S
Y
----
K
N
V
L
S
L
T
N
K
G
E
V
F
N
E
L
V
G
K
Q
R
I
S
-
G
----
N
L
--
D
S
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
48.22
36%
53
- C4 -
4WK2
4
ITB1_HUMAN
B:
[186-228]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
C
T
S
--------
E
Q
N
C
T
T
---
P
F
S
Y
----
K
N
V
L
S
L
T
N
K
G
E
V
F
N
E
L
V
G
K
Q
R
I
S
-
G
----
N
L
--
D
S
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
47.70
36%
56
- C4 -
4WK4
2
ITB1_HUMAN
B:
[186-230]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
C
T
S
--------
E
Q
N
C
T
T
---
P
F
S
Y
----
K
N
V
L
S
L
T
N
K
G
E
V
F
N
E
L
V
G
K
Q
R
I
S
-
G
----
N
L
--
D
S
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
47.39
36%
63
- C4 -
4WK0
3
ITB1_HUMAN
B:
[186-228]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
C
T
S
--------
E
Q
N
C
T
T
---
P
F
S
Y
----
K
N
V
L
S
L
T
N
K
G
E
V
F
N
E
L
V
G
K
Q
R
I
S
-
G
----
N
L
--
D
S
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
36.77
22%
37
- C4 -
3LMD
-
?
A:
[289-347]
------------------------------------------------------------------------------------------
L
E
D
D
---
E
----
T
V
N
H
-
V
L
E
L
L
S
Q
S
----
G
----
G
R
Q
A
A
L
D
E
V
Y
R
Y
M
D
I
A
N
A
E
L
D
---
R
--------------------------
L
P
D
S
T
V
K
E
----
A
L
R
N
L
A
T
F
T
V
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
36.61
22%
38
- C4 -
3Q2Q
1
?
A:
[291-349]
------------------------------------------------------------------------------------------
L
E
D
D
---
E
----
T
V
N
H
-
V
L
E
L
L
S
Q
S
----
G
----
G
R
Q
A
A
L
D
E
V
Y
R
Y
M
D
I
A
N
A
E
L
D
---
R
--------------------------
L
P
D
S
T
V
K
E
----
A
L
R
N
L
A
T
F
T
V
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
36.28
5%
-19
- C4 -
2AL3
-
ASPC1_MOUSE
A:
[28-69]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
S
T
V
L
----
L
Q
V
L
E
D
T
C
R
R
Q
D
F
N
P
S
E
Y
D
L
K
F
Q
-
R
T
V
-
L
D
L
--
S
L
Q
W
R
F
A
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
32.10
8%
34
- C4 -
2KJG
-
?
A:
[60-83]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
-
F
Y
D
M
I
A
E
I
L
--
Q
R
Y
Y
--
K
K
I
G
I
E
N
V
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
27.71
16%
191
- C4 -
2G6T
-
?
A:
[169-207]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Y
S
C
T
M
P
K
G
S
L
-
G
T
G
DN
K
I
I
L
N
F
N
H
Q
A
S
F
A
E
A
K
N
D
W
D
E
R
K
T
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------