@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0186: (2016-03-13 )
MTKEQQLAERIIAAVGGMDNIDSVMNCMTRVRIKVLDENKVDDQELRHIDGVMGVIHDERIQVVVGPGTVNKVANHMAELSGVKLGDPIPHHHNDSEKMDYKSYAADKAKANKEAHKAKQKNGKLNKVLKSIANIFIPLIPAFIGAGLIGGIAAVLSNLMVAGYISGAWITQLITVFNVIKDGMLAYLAIFTGINAAKEFGATPGLGGVIGGTTLLTGIAGKNILMNVFTGEPLQPGQGGIIGVIFAVWILSIVEKRLHKIVPNAIDIIVTPTIALLIVGLLTIFIFMPLAGFVSDSLVSVVNGIISIGGVFSGFIIGASFLPLVMLGLHHIFTPIHIEMINQSGATYLLPIAAMAGAGQVGAALALWVRCKRNTTLRNTLKGALPVGFLGIGEPLIYGVTLPLGRPFLTACIGGGIGGAVIGGIGHIGAKAIGPSGVSLLPLISDNMYLGYIAGLLAAYAGGFVCTYLFGTTKAMRQTDLLGD
Atome Classification :
(20 SA)
--.........10........20........30........40........50......-..-60........70........80........90........100.......110.......120..--.....130.......140.......150.......160.......170.......180.......190.----......200.......210---.......220.------------......230.......240.......250......--.260---........-------.270.-----------....-..280........290..---...--..300---........310.......320.......330..--...----..340------.....--..350..---.....360...----....370.......380.......390.......400..----.....410.......420.......430.-.....---..440.......450.......460.......470.......480..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--MT
K
E
Q
Q
L
A
E
R
I
I
A
A
VGGMD
N
I
D
S
V
M
N
C
M
T
R
V
R
I
K
V
LDENKV
D
D
Q
E
L
R
H
I
D
G
V
M
G
VIH-D
E
-
R
I
Q
V
V
VGPG
T
V
N
K
V
A
N
H
M
A
E
LSGVKLGDPIPHHHND
S
E
K
M
D
Y
K
S
YAA
D
K
AKA
N
K
E
A
H
K
A
K
QKNG
K
--
L
N
K
V
L
K
S
I
A
N
I
F
I
P
L
I
P
A
F
I
G
A
G
L
I
G
G
I
A
A
V
L
S
N
L
M
V
A
GYI
S
G
A
W
I
T
Q
L
I
T
V
F
N
V
I
K
D
G
M
L
A
Y
L
A
I
F
TG----
I
N
A
A
K
EFGATPGLGGVIG
G
---
T
T
L
L
T
GIAGK
N
------------
I
L
M
N
VFTGEPLQPGQGG
I
I
G
V
I
F
A
V
W
I
L
S
I
V
E
K
R
L
--
H
K
-----IVPN
A
I
D
I
-------
I
V
T
P
T
-----------
I
A
L
L
-
I
V
G
-
L
L
T
I
F
I
F
M
P
L
A
G
F
V
---
S
D
S
--
L
V
S
V
----
V
N
G
I
I
S
I
G
G
V
F
S
G
F
I
I
G
A
S
F
L
P
L
V
M
L
G
L
H
H
IFT--
P
I
H
----
I
E
M
IN------QSG
A
T
--
Y
L
L
P
I
A
A---MAGA
G
Q
V
G
A
A
L
----
A
L
W
V
R
CKRNT
T
L
R
N
T
LKGALPV
G
F
LGIGEP
L
I
Y
G
V
TLPL----G
R
P
F
L
T
A
C
IGGG
I
G
G
A
V
I
G
G
I
G
H
I
G
A
K-A-IGPSG---
V
S
L
L
P
LISDN
M
Y
L
G
Y
I
A
G
L
L
A
A
YAG
G
F
V
C
T
Y
L
FGT
T
K
A
M
R
QTDLLGD
23
HHSearch
72.18
12%
-112
- C1 -
3QNQ
8
?
A:
[12-429]
--------------------------------------------------------------------------------------------------------------------------
V
A
G
K
V
A
--
E
Q
R
H
L
L
A
I
R
D
G
L
V
L
T
M
P
F
L
I
I
G
S
I
F
L
I
I
S
T
L
P
I
P
G
-
Y
S
E
F
M
A
S
L
F
G
K
N
W
N
V
A
L
G
Y
P
V
S
A
T
F
N
I
M
A
L
I
A
V
F
G
I
A
Y
R
L
G
E
Y
Y
K
V
D
A
L
A
S
G
A
L
S
L
V
T
F
L
L
A
T
P
F
Q
V
A
Y
I
MPGTK
E
S
I
L
V
D
G
V
I
P
A
A
L
M
G
------
S
Q
G
L
F
V
A
M
I
I
A
I
I
S
T
E
I
Y
R
F
L
--
V
Q
K
KM
I
I
K
M
P
E
T
V
P
P
A
V
T
R
S
F
A
A
L
I
P
G
-----------
F
I
V
V
T
V
V
W
-
I
I
R
L
I
F
E
H
T
T
F
G
S
I
---
H
N
V
--
V
G
K
L
L
Q
E
P
L
S
I
L
G
--
A
S
L
W
G
A
V
I
A
V
I
L
V
H
V
L
W
A
C
G
I
H
G
A
T
I
V
G
G
V
M
S
P
I
W
L
S
L
M
D
Q
N
R
I
A
F
Q
A
G
Q
D
VP
N
T
I
T
A
Q
F
FDL
W
I
Y
M
G
G
S
G
A
T
L
A
L
V
V
G
M
L
L
F
A
R
-
S
Q
Q
L
K
S
L
G
R
L
S
I
A
P
G
I
F
N
I
N
E
M
V
T
F
G
M
P
I
V
M
NP
L
L
L
I
P
F
I
V
V
P
V
V
L
T
I
V
S
Y
F
A
M
E
W
G
L
V
A
R
P
S
G
A
A
V
T
W
T
TPI
L
F
S
G
Y
L
G
S
G
G
-
K
I
S
G
V
I
L
Q
L
V
N
F
A
L
A
F
V
I
Y
L
P
F
L
K
I
W
D
K
Q
K
I
A
E
---
33
Fugue
69.03
29%
-71
- C1 -
3IPJ
1
?
A:
[1-95]
SN
A
N
K
Y
N
K
I
A
N
E
L
I
K
I
I
G
-
E
D
N
I
I
S
I
T
H
C
A
T
R
L
R
V
M
V
K
D
R
E
I
I
N
D
K
K
V
E
K
V
D
E
V
K
G
V
F
F
T
S
G
-
Q
Y
Q
I
I
L
G
T
G
I
V
N
K
V
Y
A
E
V
E
K
M
G
L
K
T
L
S
K
K
E
Q
D
E
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
68.62
31%
-74
- C1 -
3IPJ
1
?
A:
[3-86]
--
A
N
K
Y
N
K
I
A
N
E
L
I
K
I
I
-
G
E
D
N
I
I
S
I
T
H
C
A
T
R
L
R
V
M
V
K
D
R
E
I
I
N
D
K
K
V
E
K
V
D
E
V
K
G
V
F
F
T
S
G
-
Q
Y
Q
I
I
L
G
T
G
I
V
N
K
V
Y
A
E
V
E
K
M
G
L
K
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
67.52
36%
-79
- C1 -
3IPJ
2
?
B:
[5-75]
----
K
Y
N
K
I
A
N
E
L
I
K
I
I
G
-
E
D
N
I
I
S
I
T
H
C
A
T
R
L
R
V
M
V
K
D
R
E
I
I
N
D
K
K
V
E
K
V
D
E
V
K
G
V
F
F
-
T
S
G
Q
Y
Q
I
I
L
G
T
G
I
V
N
K
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
67.37
30%
-94
- C1 -
3BP3
1
PTGCB_ECOLI
A:
[2-81]
----
G
T
S
E
M
A
P
A
L
V
A
A
F
G
G
K
E
N
I
T
N
L
D
A
C
I
T
R
L
R
V
S
V
A
D
V
S
K
V
D
Q
A
G
L
K
K
L
-
G
A
A
G
V
V
V
A
G
S
-
G
V
Q
A
I
F
G
T
K
-
S
D
N
L
K
T
E
M
D
E
Y
I
R
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
66.92
36%
-81
- C1 -
3IPJ
1
?
A:
[5-75]
----
K
Y
N
K
I
A
N
E
L
I
K
I
I
G
-
E
D
N
I
I
S
I
T
H
C
A
T
R
L
R
V
M
V
K
D
R
E
I
I
N
D
K
K
V
E
K
V
D
E
V
K
G
V
F
F
-
T
S
G
Q
Y
Q
I
I
L
G
T
G
I
V
N
K
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
64.04
25%
-133
- C1 -
1FFT
3
CYOB_ECOLI
A:
[287-438]
--------------------------------------------------------------------------------------------------------------------------------------------
V
Y
I
L
I
L
P
V
F
---
G
V
F
S
E
I
A
A
T
F
S
R
K
R
L
F
G
Y
T
S
L
V
W
A
T
V
C
I
T
V
L
S
F
I
-----
V
W
L
H
H
F
F
T
----
M
------
G
A
G
A
N
V
N
A
F
F
G
I
---
T
T
M
I
I
A
I
P
---------------------------------
T
G
V
K
I
F
N
W
L
F
T
M
Y
Q
G
R
I
V
F
H
S
-----
A
M
L
W
T
I
G
F
-------
I
V
T
F
S
-----------
V
G
-----
G
-
M
T
G
V
L
L
A
V
P
G
A
D
F
V
LHN
S
L
F
--
L
I
A
H
----
F
H
N
V
I
-
I
G
G
V
V
F
G
C
F
A
G
M
T
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
60.49
25%
-130
- C1 -
3DIN
-
SECY_THEMA
C:
[248-390]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
G
R
R
------------
V
Y
G
G
A
S
T
Y
L
P
I
K
V
N
Q
G
G
V
I
P
I
I
F
A
S
A
I
V
S
I
----------------
P
S
A
I
A
S
-------
I
T
N
N
E
TLKNLFRAGGF
L
Y
L
L
-
I
Y
G
-
L
L
-
V
F
F
F
T
Y
F
Y
S
V
V
---
I
F
D
--
P
R
E
I
----
S
E
N
I
R
K
Y
G
G
Y
I
P
G
L
R
P
G
R
S
----
T
E
Q
Y
L
H
R
V
-----------
L
N
R
V
T
------
F
I
G
A
V
--
F
L
V
V
I
A
L
---
L
P
Y
L
V
Q
G
A
I
K
V
----
N
V
W
I
----------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
59.15
31%
-38
- C1 -
3BP3
1
PTGCB_ECOLI
A:
[1-70]
---
T
G
T
S
E
M
A
P
A
L
V
A
A
F
G
G
K
E
N
I
T
N
L
D
A
C
I
T
R
L
R
V
S
V
A
D
V
S
K
V
D
Q
A
G
L
K
K
L
G
A
A
G
V
V
V
A
-
G
S
-
G
V
Q
A
I
F
G
T
K
S
D
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
58.66
31%
-51
- C1 -
1O2F
-
B:
[314-379]
-------
E
M
A
A
A
L
V
A
A
F
G
G
K
E
N
I
T
N
L
D
A
C
I
T
R
L
R
V
S
V
A
D
V
S
K
V
D
Q
A
G
L
K
K
L
G
A
A
G
V
V
V
A
-
G
S
-
G
V
Q
A
I
F
G
T
K
S
D
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
55.71
30%
-79
- C1 -
1IBA
-
A:
[15-92]
--------
M
A
P
A
L
V
A
A
F
G
G
K
E
N
I
T
N
L
D
A
C
I
T
R
L
R
V
S
V
A
D
V
S
K
V
D
Q
A
G
L
K
K
L
-
G
A
A
G
V
V
V
A
G
S
-
G
V
Q
A
I
F
G
T
K
-
S
D
N
L
K
T
E
M
D
E
Y
I
R
N
F
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
55.47
29%
-39
- C1 -
3NCY
-
ADIC_SALTY
A:
[227-362]
---------------------------------------------------------------------------------------------------------------------------------------------------
A
T
I
G
G
V
L
I
A
A
V
C
Y
V
L
S
T
T
A
I
M
G
M
I
P
N
A
A
L
R
V
S
A
S
P
F
-----
G
D
A
A
R
M
A
L
G
D
T
----
A
G
A
I
V
S
F
C
A
A
A
G
C
L
G
S
L
G
G
---
W
T
L
L
A
G
Q
T
A
K
------------------------
A
A
A
D
D
G
L
F
P
P
I
F
A
---------
R
---------------------------
T
P
V
-----------
A
G
L
L
-
I
V
G
V
L
M
T
I
F
Q
F
S
S
M
S
P
N
A
---
A
K
E
F
G
L
V
S
S
----
V
S
V
I
F
T
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
55.12
32%
-36
- C1 -
3BP3
1
B:
[7-70]
---------
A
P
A
L
V
A
A
F
G
G
K
E
N
I
T
N
L
D
A
C
I
T
R
L
R
V
S
V
A
D
V
S
K
V
D
Q
A
G
L
K
K
L
G
A
A
G
V
V
V
A
-
G
S
-
G
V
Q
A
I
F
G
T
K
S
D
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
53.87
32%
-49
- C1 -
3BP8
-
PTGCB_ECOLI
C:
[1-65]
--------
M
A
P
A
L
V
A
A
F
G
G
K
E
N
I
T
N
L
D
A
C
I
T
R
L
R
V
S
V
A
D
V
S
K
V
D
Q
A
G
L
K
K
L
G
A
A
G
V
V
V
A
-
G
S
-
G
V
Q
A
I
F
G
T
K
S
D
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
50.37
24%
40
- C1 -
3ZG0
1
?
A:
[368-450]
---------------------------------------------------------------
K
F
Q
I
T
T
S
P
G
S
T
Q
K
I
L
T
A
M
I
G
L
N
N
K
T
L
D
D
------
K
T
S
Y
K
I
D
G
K
G
W
Q
K
D
K
S
W
G
G
Y
N
V
T
R
Y
E
V
V
N
G
N
ID
L
K
Q
A
I
E
S
S
D
N
I
F
F
A
R
V
A
L
E
L
G
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
50.29
24%
53
- C1 -
3ZFZ
1
?
A:
[368-457]
---------------------------------------------------------------
K
F
Q
I
T
T
S
P
G
S
T
Q
K
I
L
T
A
M
I
G
L
N
N
K
T
L
D
D
------
K
T
S
Y
K
I
D
G
K
G
W
Q
K
D
K
S
W
G
G
Y
N
V
T
R
Y
E
V
V
N
G
N
ID
L
K
Q
A
I
E
S
S
D
N
I
F
F
A
R
V
A
L
E
L
G
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
50.02
24%
44
- C1 -
4DKI
1
?
A:
[372-457]
---------------------------------------------------------------
K
F
Q
I
T
T
S
P
G
S
T
Q
K
I
L
T
A
M
I
G
L
N
N
K
T
L
D
D
------
K
T
S
Y
K
I
D
G
K
G
W
Q
K
D
K
S
W
G
G
Y
N
V
T
R
Y
E
V
V
N
G
N
ID
L
K
Q
A
I
E
S
S
D
N
I
F
F
A
R
V
A
L
E
L
G
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
49.93
24%
54
- C1 -
1VQQ
-
?
A:
[372-460]
---------------------------------------------------------------
K
F
Q
I
T
T
S
P
G
S
T
Q
K
I
L
T
A
M
I
G
L
N
N
K
T
L
D
D
------
K
T
S
Y
K
I
D
G
K
G
W
Q
K
D
K
S
W
G
G
Y
N
V
T
R
Y
E
V
V
N
G
N
ID
L
K
Q
A
I
E
S
S
D
N
I
F
F
A
R
V
A
L
E
L
G
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
49.29
31%
-35
- C1 -
1IBA
-
A:
[15-79]
--------
M
A
P
A
L
V
A
A
F
G
G
K
E
N
I
T
N
L
D
A
C
I
T
R
L
R
V
S
V
A
D
V
S
K
V
D
Q
A
G
L
K
K
L
G
A
A
G
V
V
V
A
-
G
S
-
G
V
Q
A
I
F
G
T
K
S
D
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
49.26
24%
50
- C1 -
4CJN
-
?
A:
[368-450]
---------------------------------------------------------------
K
F
Q
I
T
T
S
P
G
S
T
Q
K
I
L
T
A
M
I
G
L
N
N
K
T
L
D
D
------
K
T
S
Y
K
I
D
G
K
G
W
Q
K
D
K
S
W
G
G
Y
N
V
T
R
Y
E
V
V
N
G
N
ID
L
K
Q
A
I
E
S
S
D
N
I
F
F
A
R
V
A
L
E
L
G
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------