@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0660: (2015-12-17 )
MVDAFFQIIVLLFSLFLGARLGGLGVGYAGGLGVLILCLFLGLNPGKIPFDVILIIMAVISAISAMQKAGGLDYLVQIAEKILRKHPKQINYLAPSVAYFLTILAGTGHTVFSLIPVIVEVSQSQNIKPKAPLSLAVVSSQVAITASPVSAAVVFMSGILEPLGADYLTLLMVWIPTTFLACMLTAFVMGFTDLKLDSDPNYLERLKAGKISPPMMKKEKETSKSAKLSLWIFIGGVVAIVFYASAISKNIALISPVILGRDYAIVSFMLSVATLIAIFCKINANEIAHSSVFKSGMQACVCVLGVAWLGDTFVSNHIDEIKRYASFLIADYPFLLAVALFLASMLLYSQAATSKALIPSVITALGISANHTEHLYIIVASFASVSALFVLPTYPTLLGAIAMDHTGTTKMGRYVFDHAFLIPGVLVVFLSVALGFVVAPLVL
Atome Classification :
(20 SA)
------------.........10.--.......20------.........30.....------------...40........50.......--.60........70..----..-....80..---......90......--..100-.......110------------------------......----...120.......130------........140.......-----.150.......160.......170--.......180.......190------........200.......210...----...----.220.......230.......---------------------.240.......-----250.-......260---....--....270.......280.......290-------------....----------..-----------------..300.------.....-.310.......320........330..-..--------...340.......350-------.......360.......370.......380.......390.......400.......410....--...420.--......430.------......440.---------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------M
V
D
A
F
F
Q
I
I
V
L
L
--
F
S
L
F
L
G
AR-------LGGLGVGYAG
G
L
G
V
L
I
------------
L
C
L
F
LGLNPGK
I
P
F
D
V
I
L
I
I
M
A
--
V
I
S
A
I
S
A
M
Q
KAG
G
L
D
----
Y
L
-
V
Q
I
A
E
K
I
L
---
R
KHPKQINYL
A
P
S
V
--
A
Y
F
L
T
-
I
LAGTG
H
T
--------------------------
V
F
S
L
I
P
----
V
I
V
EVSQSQNIKPKA-------
P
L
S
L
A
V
V
S
S
Q
-
V
A
I
TAS
P
-----
V
S
A
A
V
V
F
M
S
G
I
L
E
PL
G
A
D
Y
L
T
L
L
M
--
V
W
I
P
T
T
F
L
A
C
M
L
T
A
F
V
MG
F
-------
T
D
L
KLDSD
P
N
Y
L
E
R
L
KAGKISP
P
M
----
M
K
K
----
E
K
ETSKSA
K
L
S
L
-
W
I
F
I
G
G
V
V
---------------------
A
I
V
F
Y
A
S
A
I
SK-----N
I
A
L
-
I
S
P
V
ILGR----
D
Y
A
I
--
V
S
F
M
L
S
V
A
T
L
I
A
I
F
CKI
N
A
N
E
I
A
H
S
S
--------------
V
F
K
S
----------
G
M
-----------------
Q
A
C
V
C
V
------
L
G
V
A
W
-
L
G
D
T
F
V
S
N
H
I
D
E
I
-
K
R
Y
A
S
F
L
IAD
Y
P
F
-
L
L
--------
A
V
A
L
F
L
A
S
M
L
L
Y
S
QAA-------TSK
A
L
I
P
S
V
I
T
A
LGISANHT
E
H
L
Y
I
I
VASFAS
V
S
A
L
F
VLPT
Y
P
T
L
L
G
A
I
AMDHTGT
T
K
M
G
R
Y
V
F
--
D
H
A
F
L
I
P
--
G
V
L
V
V
F
L
S
V
A
------
L
G
F
V
V
A
P
LVL---------------------------------------
23
Fugue
84.67
17%
-140
- C1 -
4MND
4
DIPPS_ARCFU
A:
[40-457]
----------------
L
M
K
A
V
I
L
A
--
A
G
L
G
G
G
V
P
-------
K
P
L
V
R
V
G
-----
G
C
E
I
------------
I
L
R
T
M
K
L
L
S
P
H
V
S
-
E
F
I
I
V
A
S
R
--
Y
A
D
D
I
D
A
F
L
K
D
K
G
F
N
----
Y
K
-
I
V
R
H
D
R
P
E
---
K
G
N
G
Y
S
L
L
V
A
K
N
H
V
ED
R
F
I
L
T
-
M
----
G
D
H
--------------------------
V
Y
S
--------------
Q
Q
F
I
E
K
A
V
-------
R
G
E
G
V
I
A
D
R
E
-
P
R
F
V
D
I
G
-----
E
A
T
K
I
R
V
E
D
G
R
V
A
K
I
G
K
D
L
R
E
--
F
--
D
C
V
D
T
G
F
F
V
L
D
-
D
S
I
F
E
H
A
-------
E
K
L
R
D
R
E
E
I
P
L
S
E
I
V
K
L
A
R
L
P
V
T
Y
----
V
D
G
E
L
W
M
D
V
D
T
K
E
D
V
R
R
A
N
-
R
A
L
V
S
A
A
V
---------------------
G
D
G
F
I
S
R
K
I
N
R
-----
K
I
S
T
R
I
S
A
A
I
V
N
K
VN
P
N
Q
M
T
L
--
I
S
F
L
V
G
A
F
S
A
L
A
S
F
--
F
S
I
P
L
A
G
L
L
Y
--------------
Q
F
S
S
----------
I
L
-----------------
D
G
C
D
G
E
------
I
A
R
A
S
-
L
K
M
S
K
K
G
G
Y
V
D
S
I
L
D
R
F
V
D
F
L
F
L
A
I
I
A
-
L
L
Y
PKT
A
T
V
A
M
F
A
I
F
G
S
V
M
V
S
Y
T
S
E
K
-------
Y
K
A
E
F
G
E
S
I
R
V
L
N
Y
I
P
G
K
R
D
E
R
I
F
L
I
M
I
F
C
L
L
S
A
I
S
L
-----------------------
Q
W
I
F
--
W
M
F
L
F
V
A
--
A
I
S
L
T
R
V
V
V
T
------
L
L
A
V
L
V
S
------------------------------------------
29
Fugue
81.72
19%
-104
* C2 *
4OV8
9
?
A:
[6-472]
-----DT
L
N
D
V
I
Q
D
P
T
R
R
N
K
L
I
N
D
--
N
N
L
L
K
G
I
I
-------
M
G
---------------------------------
R
D
G
P
V
P
S
S
R
E
L
I
V
R
P
D
T
L
R
A
I
I
N
N
R
A
T
I
E
T
T
T
----
M
E
-
A
E
F
T
E
T
L
M
---
E
S
-----
N
Y
N
S
A
S
V
--
K
V
S
A
P
C
I
T
A
N
S
E
Y
S
--------------------------
E
S
S
S
F
K
N
T
ET
E
K
S
M
Y
T
S
S
R
Y
L
F
P
Q
G
-------
R
I
D
F
T
T
P
D
S
G
-
D
V
I
K
L
S
P
Q
F
T
S
G
V
Q
A
A
L
A
K
A
T
G
T
E
K
R
E
A
L
Q
N
L
F
Q
E
Y
GC
V
F
R
T
K
V
H
I
G
G
V
L
S
A
H
T
M
E
T
F
S
RSEN
E
T
E
V
K
Q
D
V
K
A
G
L
E
G
A
V
K
G
W
G
G
G
A
T
A
GH
G
N
T
Q
G
----
T
I
T
T
S
Q
N
R
K
L
N
V
K
Y
I
V
N
G
G
---------------------------
D
Y
T
K
I
Q
N
-----
T
E
E
W
-
V
A
S
T
N
Q
S
E
----
H
W
R
V
IE
V
T
E
V
T
A
V
A
D
L
L
P
Q
P
I
R
G
Q
V
K
D
L
L
K
P
L
--------------
L
G
K
W
V
D
V
E
K
V
P
GLE
S
L
-----------------
P
V
S
V
Y
R
P
KGAIP
A
G
W
F
W
-
L
G
D
T
A
D
A
S
K
A
L
L
V
-
K
P
T
L
P
A
R
S
G
R
N
P
A
-
L
T
--------
S
--
L
H
Q
G
S
G
M
-
T
E
Q
P
F
-------
V
D
L
P
Q
Y
Q
Y
L
S
T
Y
F
G
S
F
A
H
D
T
P
P
----
G
S
T
L
R
G
L
R
P
D
H
V
L
P
G
R
Y
E
M
H
G
D
T
I
S
T
A
V
Y
V
T
R
P
V
D
V
P
F
PE
D
E
A
F
D
L
K
--
S
L
V
R
V
K
L
P
G
S
GNPPKP
R
S
A
L
K
K
S
M
V
L
FD-------------------------------------
26
Fugue
69.76
15%
-142
- C1 -
4X0Q
7
DPOLQ_HUMAN
A:
[6-772]
S
L
S
I
I
DVASDQ
N
L
F
Q
T
F
I
K
E
W
R
C
K
K
R
F
S
I
S
L
A
C
E
K
I
RDDTL
V
V
G
L
A
V
C
W
G
G
R
D
A
Y
Y
F
S
LL
D
P
S
L
T
LK
D
R
M
W
Y
L
Q
S
C
L
R
K
E
S
D
K
E
C
S
V
V
I
Y
D
--
F
I
Q
S
Y
K
I
L
L
L
S
C
G
I
S
LE
Q
S
Y
E
D
P
K
V
A
C
W
L
L
DPD
S
Q
E
P
T
L
H
S
I
V
T
S
F
L
--
P
H
E
L
P
-
L
L
E
G
M
E
T
S
QGIQSLGLNAGSEHSGR
Y
R
A
S
V
E
S
I
L
I
F
N
S
M
N
----
Q
L
N
S
L
L
Q
K
E
N
L
Q
D
V
F
RKV
E
M
P
S
Q
Y
C
L
A
L
L
E
L
N
G
I
G
F
S
T
A
E
-----
C
E
S
Q
K
H
I
M
Q
A
K
L
D
A
I
E
T
Q
A
Y
Q
L
A
G
--
H
S
F
S
F
T
S
S
D
D
I
A
E
V
L
F
L
E
L
K
------
L
P
P
Q
F
S
T
S
K
D
V
L
N
K
L
K
A
L
H
P
L
P
G
L
----
I
L
E
----
W
R
R
I
T
N
A
I
T
K
V
V
-
F
P
L
Q
R
E
K
C
LNPFLG
M
E
R
I
Y
P
V
S
Q
S
HTATG
R
I
T
F
T
E
P
N
I
Q
N
VP
R
D
F
E
I
K
M
-
G
M
P
F
S
I
S
M
----
R
H
A
F
--
V
P
F
-
P
G
G
S
I
L
A
A
D
Y
S
Q
L
E
L
R
I
L
A
H
L
S
HD
R
R
L
I
Q
V
L
N
T
GAD
V
F
R
S
----------
I
A
A
E
W
KMIEPESVG
D
D
L
R
Q
Q
A
K
Q
I
C
------
Y
G
I
I
Y
G
M
G
A
K
S
L
G
E
Q
M
G
I
K
-
E
N
D
A
A
C
Y
I
D
S
F
K
S
R
Y
T
--------
G
I
N
Q
F
M
T
E
T
V
K
N
C
K
R
D
G
F
V
Q
T
IL
G
R
R
R
Y
L
P
G
I
K
D
N
N
P
Y
R
K
A
H
A
E
R
Q
A
I
N
T
I
V
Q
G
S
A
A
D
I
V
K
I
A
T
V
N
I
Q
K
Q
L
E
T
F
H
S
T
F
K
S
H
G
H
R
E
G
M
--
L
Q
S
D
C
P
I
R
G
G
F
F
I
L
Q
L
H
D
E
------
L
L
Y
E
V
A
E
E
D
V
V
Q
V
A
Q
I
V
K
N
E
M
E
S
AVKLS
V
K
L
K
V
K
V
K
I
G
A
S
W
G
E
L
K
D
F
D
V
3
PsiBlast_PDB
47.99
30%
59
- C1 -
2W2V
1
RAC2_HUMAN
A:
[95-143]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
Y
E
N
V
R
A
--
K
W
F
P
E
V
R
H
H
C
P
S
T
P
I
I
L
V
G
-------
T
K
L
D
L
R
D
D
K
D
T
I
E
K
L
K
E
K
K
L
A
P
I
T
----
Y
P
Q
----
G
L
A
L
A
K
E
I
D
S
V
K
-
Y
L
E
C
S
A
L
T
---------------------
Q
R
G
L
K
T
V
F
D
E
A
-----
I
R
A
V
-
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
46.59
30%
57
- C1 -
2W2X
1
RAC2_HUMAN
A:
[94-142]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
Y
E
N
V
R
A
--
K
W
F
P
E
V
R
H
H
C
P
S
T
P
I
I
L
V
G
-------
T
K
L
D
L
R
D
D
K
D
T
I
E
K
L
K
E
K
K
L
A
P
I
T
----
Y
P
Q
----
G
L
A
L
A
K
E
I
D
S
V
K
-
Y
L
E
C
S
A
L
T
---------------------
Q
R
G
L
K
T
V
F
D
E
A
-----
I
R
A
V
-
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
46.50
30%
56
- C1 -
2W2T
1
RAC2_HUMAN
A:
[94-142]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
Y
E
N
V
R
A
--
K
W
F
P
E
V
R
H
H
C
P
S
T
P
I
I
L
V
G
-------
T
K
L
D
L
R
D
D
K
D
T
I
E
K
L
K
E
K
K
L
A
P
I
T
----
Y
P
Q
----
G
L
A
L
A
K
E
I
D
S
V
K
-
Y
L
E
C
S
A
L
T
---------------------
Q
R
G
L
K
T
V
F
D
E
A
-----
I
R
A
V
-
L
C
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
46.10
30%
57
- C1 -
1DS6
1
RAC2_HUMAN
A:
[88-136]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
Y
E
N
V
R
A
--
K
W
F
P
E
V
R
H
H
C
P
S
T
P
I
I
L
V
G
-------
T
K
L
D
L
R
D
D
K
D
T
I
E
K
L
K
E
K
K
L
A
P
I
T
----
Y
P
Q
----
G
L
A
L
A
K
E
I
D
S
V
K
-
Y
L
E
C
S
A
L
T
---------------------
Q
R
G
L
K
T
V
F
D
E
A
-----
I
R
A
V
-
L
C
P
Q
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
44.53
32%
136
- C1 -
1GZS
1
CDC42_HUMAN
A:
[99-138]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
V
P
E
I
T
H
H
C
P
K
T
P
F
L
L
V
G
-------
T
Q
I
D
L
R
D
D
P
S
T
I
E
K
L
A
K
N
K
Q
K
P
I
T
----
P
E
T
----
A
E
K
L
A
R
D
L
K
A
V
K
-
Y
V
E
C
S
A
L
T
---------------------
Q
K
G
L
K
N
V
F
D
E
A
-----
I
L
A
A
-
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
44.14
32%
138
- C1 -
2NGR
1
CDC42_HUMAN
A:
[97-136]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
V
P
E
I
T
H
H
C
P
K
T
P
F
L
L
V
G
-------
T
Q
I
D
L
R
D
D
P
S
T
I
E
K
L
A
K
N
K
Q
K
P
I
T
----
P
E
T
----
A
E
K
L
A
R
D
L
K
A
V
K
-
Y
V
E
C
S
A
L
T
---------------------
Q
K
G
L
K
N
V
F
D
E
A
-----
I
L
A
A
-
L
E
P
P
E
P
K
K
----
S
R
R
C
--
V
L
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
44.01
32%
140
- C1 -
4YDH
1
CDC42_HUMAN
B:
[99-138]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
V
P
E
I
T
H
H
C
P
K
T
P
F
L
L
V
G
-------
T
Q
I
D
L
R
D
D
P
S
T
I
E
K
L
A
K
N
K
Q
K
P
I
T
----
P
E
T
----
A
E
K
L
A
R
D
L
K
A
V
K
-
Y
V
E
C
S
A
L
T
---------------------
Q
R
G
L
K
N
V
F
D
E
A
-----
I
L
A
A
-
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
43.80
32%
140
- C1 -
3GCG
-
CDC42_HUMAN
A:
[97-136]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
V
P
E
I
T
H
H
C
P
K
T
P
F
L
L
V
G
-------
T
Q
I
D
L
R
D
D
P
S
T
I
E
K
L
A
K
N
K
Q
K
P
I
T
----
P
E
T
----
A
E
K
L
A
R
D
L
K
A
V
K
-
Y
V
E
C
S
A
L
T
---------------------
Q
K
G
L
K
N
V
F
D
E
A
-----
I
L
A
A
-
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
43.73
32%
143
- C1 -
3VHL
-
CDC42_HUMAN
B:
[104-143]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
V
P
E
I
T
H
H
C
P
K
T
P
F
L
L
V
G
-------
T
Q
I
D
L
R
D
D
P
S
T
I
E
K
L
A
K
N
K
Q
K
P
I
T
----
P
E
T
----
A
E
K
L
A
R
D
L
K
A
V
K
-
Y
V
E
C
S
A
L
T
---------------------
Q
K
G
L
K
N
V
F
D
E
A
-----
I
L
A
A
-
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
43.51
32%
143
- C1 -
1AM4
1
CDC42_HUMAN
D:
[97-136]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
V
P
E
I
T
H
H
C
P
K
T
P
F
L
L
V
G
-------
T
Q
I
D
L
R
D
D
P
S
T
I
E
K
L
A
K
N
K
Q
K
P
I
T
----
P
E
T
----
A
E
K
L
A
R
D
L
K
A
V
K
-
Y
V
E
C
S
A
L
T
---------------------
Q
R
G
L
K
N
V
F
D
E
A
-----
I
L
A
A
-
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
43.46
32%
141
- C1 -
3QBV
1
CDC42_HUMAN
A:
[97-136]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
V
P
E
I
T
H
H
C
P
K
T
P
F
L
L
V
G
-------
T
Q
I
D
L
R
D
D
P
S
T
I
E
K
L
A
K
N
K
Q
K
P
I
T
----
P
E
T
----
A
E
K
L
A
R
D
L
K
A
V
K
-
Y
V
E
C
S
A
L
T
---------------------
Q
K
G
L
K
N
V
F
D
E
A
-----
I
L
A
A
-
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
43.36
32%
136
- C1 -
1GRN
1
CDC42_HUMAN
A:
[97-136]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
V
P
E
I
T
H
H
C
P
K
T
P
F
L
L
V
G
-------
T
Q
I
D
L
R
D
D
P
S
T
I
E
K
L
A
K
N
K
Q
K
P
I
T
----
P
E
T
----
A
E
K
L
A
R
D
L
K
A
V
K
-
Y
V
E
C
S
A
L
T
---------------------
Q
K
G
L
K
N
V
F
D
E
A
-----
I
L
A
A
-
L
E
P
P
E
P
K
K
----
S
R
R
C
--
V
L
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
43.35
32%
142
- C1 -
3EG5
1
CDC42_MOUSE
A:
[97-136]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
V
P
E
I
T
H
H
C
P
K
T
P
F
L
L
V
G
-------
T
Q
I
D
L
R
D
D
P
S
T
I
E
K
L
A
K
N
K
Q
K
P
I
T
----
P
E
T
----
A
E
K
L
A
R
D
L
K
A
V
K
-
Y
V
E
C
S
A
L
T
---------------------
Q
R
G
L
K
N
V
F
D
E
A
-----
I
L
A
A
-
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
43.23
32%
130
- C1 -
4YC7
1
CDC42_HUMAN
A:
[99-138]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
V
P
E
I
T
H
H
C
P
K
T
P
F
L
L
V
G
-------
T
Q
I
D
L
R
D
D
P
S
T
I
E
K
L
A
K
N
K
Q
K
P
I
T
----
P
E
T
----
A
E
K
L
A
R
D
L
K
A
V
K
-
Y
V
E
C
S
A
L
T
---------------------
Q
R
G
L
K
N
V
F
D
E
A
-----
I
L
A
A
-
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
42.61
32%
130
- C1 -
2DFK
-
CDC42_HUMAN
B:
[100-139]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
V
P
E
I
T
H
H
C
P
K
T
P
F
L
L
V
G
-------
T
Q
I
D
L
R
D
D
P
S
T
I
E
K
L
A
K
N
K
Q
K
P
I
T
----
P
E
T
----
A
E
K
L
A
R
D
L
K
A
V
K
-
Y
V
E
C
S
A
L
T
---------------------
Q
K
G
L
K
N
V
F
D
E
A
-----
I
L
A
A
-
L
E
P
K
S
R
R
C
----
V
L
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
42.49
32%
130
* C1 *
4ITR
2
CDC42_HUMAN
C:
[97-136]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
V
P
E
I
T
H
H
C
P
K
T
P
F
L
L
V
G
-------
T
Q
I
D
L
R
D
D
P
S
T
I
E
K
L
A
K
N
K
Q
K
P
I
T
----
P
E
T
----
A
E
K
L
A
R
D
L
K
A
V
K
-
Y
V
E
C
S
A
L
T
---------------------
Q
K
G
L
K
N
V
F
D
E
A
-----
I
L
A
A
-
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
40.33
32%
133
- C1 -
1DOA
1
CDC42_HUMAN
A:
[100-137]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
V
P
E
I
T
H
H
C
P
K
T
P
F
L
L
V
G
-------
T
Q
I
D
L
R
D
D
P
S
T
I
E
K
L
A
K
N
K
Q
K
P
I
T
----
P
E
T
----
A
E
K
L
A
R
D
L
K
A
V
K
-
Y
V
E
C
S
A
L
T
---------------------
Q
K
G
L
K
N
V
F
D
E
A
-----
I
L
A
A
-
L
E
P
P
E
P
K
K
----
S
R
R
C
--
M
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------