@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0968: (2015-12-19 )
MISKFLLKSMFKQWKNGDYQVVFWDNSVYRNGEHSPKFTLKIHRPLKFSDIKKDMSLTIAEAYMDGVIDIEGSMDEVMHSLYLQTNYEHLHKHDSAKAVQKPLKESSNISKHYDLGNDFYSIWLDETLSYSCAYFKKDDDTLHAAQLQKLDHTLKKLHLKQGEKLLDIGCGWGYLSIKAAQEYGAEVMGITISSEQYKQANKRVQELGLEDKVTIKLLNYQDLDGRLYRFDKVVSVGMFEHVGKDNLPFYFKKVKEVLKRGGMFLLHSILCCFEGKTNAWVDKYIFPGGYLPSLREVMSVMSECDFHLLMAESLRIHYAKTLDIWRDNFNHNLDQVKRLGYDERFIRMWDLYLRTCASAFRVGSADLFQLLLTNSVDNTFPLTKEYIYQ
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100........110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240------.....-------...250.......260.......270.-------------...------..--------------.-------..--------------280..-------.....290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
I
S
K
F
L
L
K
S
M
F
K
Q
WKNG
D
Y
Q
V
V
F
WDNSVYRNGEHSP
K
F
T
L
K
IHRPL
K
F
S
D
I
K
K
D
M
S
L
T
I
A
E
A
YMD
G
V
I
DIEG
S
M
D
E
V
M
H
S
L
Y
LQT
N
Y
E
H
L
H
KHD
S
A
K
A
V
Q
-
K
P
L
K
ESSNISKHYDLG
N
D
F
Y
S
I
W
L
DETLSY
S
C
A
Y
FKKDDD
T
L
H
A
A
Q
L
Q
K
L
D
H
T
L
K
K
L
H
L
KQG
E
K
L
L
D
IGCGW
G
Y
L
S
I
K
A
A
Q
EYGA
E
V
M
G
I
T
I
S
S
E
Q
Y
K
Q
A
N
K
R
V
Q
E
LGLE
D
K
V
T
I
K
L
L
NYQDLDG
R
L
Y
R
F
D
K
V
V
S
V
G
M
F
E
H-------VGKDN-------L
P
F
Y
F
K
K
V
K
E
V
L
K
RG
G
M
F
L
L
H
S
I
L
--
C
-------------
C
FE------GK--------------T-------NA--------------
W
V
DKY-------IFPGGY
L
P
S
L
R
E
V
M
S
V
M
S
EC
D
F
H
L
L
M
A
E
S
L
R
I
H
Y
A
K
T
L
D
I
W
RDNFNH
N
L
D
Q
V
K
R
LGY
D
E
R
F
I
R
M
W
D
L
Y
L
R
T
C
A
S
A
FRVG
S
A
D
L
F
Q
L
L
L
TNSVDNTFP
L
T
K
E
YIYQ
80
HHSearch
83.98
36%
-92
- C2 -
1KPG
3
CMAS1_MYCTU
A:
[4-287]
-----------------------------------------------------------------------------------------------------
E
L
K
P
H
F
A
N
V
Q
A
H
Y
D
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
Y
F
E
R
D
D
M
T
L
Q
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
G
L
Q
P
G
M
T
L
L
D
V
G
C
G
W
G
A
T
M
M
R
A
V
E
K
Y
D
V
N
V
V
G
L
T
L
S
K
N
Q
A
N
H
V
Q
Q
L
V
A
N
S
E
N
L
R
S
K
R
V
L
L
A
G
W
E
Q
F
D
E
---
P
V
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
E
R
-------
Y
D
A
F
F
S
L
A
H
R
L
L
P
A
D
G
V
M
L
L
H
T
I
T
--
G
-------------
L
H
P
------
K
E
I
H
E
R
GLPM
S
F
T
F
A
R
F
-------
L
K
--------------
F
I
V
T
E
-------
I
F
P
G
G
R
L
P
S
I
P
M
V
Q
E
C
A
S
A
N
G
F
T
V
T
R
V
Q
S
L
Q
P
H
Y
A
K
T
L
D
L
W
S
A
A
L
Q
A
N
K
G
Q
A
I
A
L
-
Q
S
E
E
V
Y
E
R
Y
M
K
Y
L
T
G
C
A
E
M
F
R
I
G
Y
I
D
V
N
Q
F
T
C
Q
K
---------------
5
PsiBlast_PDB
82.86
33%
-97
- C2 -
1TPY
3
MMAA2_MYCTU
A:
[11-286]
------------------------------------------------------------------------------------------------------------
D
V
Q
A
H
Y
D
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
H
F
E
R
E
D
M
T
L
E
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
G
L
Q
P
G
M
T
L
L
D
I
G
C
G
W
G
A
T
M
R
R
A
I
A
Q
Y
D
V
N
V
V
G
L
T
L
S
K
N
Q
A
A
H
V
Q
K
S
F
D
E
M
D
T
P
R
D
R
R
V
L
L
A
G
W
E
Q
F
N
E
P
V
---
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
D
R
-------
H
A
D
F
F
A
R
A
H
K
I
L
P
P
D
G
V
L
L
L
H
T
I
T
--
G
-------------
L
T
R
------
Q
Q
--------------
M
V
D
H
GLPL
T
L
--------------
W
L
A
R
F
L
K
F
I
A
T
E
I
F
P
G
G
Q
P
P
T
I
E
M
V
E
E
Q
S
A
K
T
G
F
T
L
T
R
R
Q
S
L
Q
P
H
Y
A
R
T
L
D
L
W
A
E
A
L
Q
E
H
K
S
E
A
I
A
I
Q
S
E
E
V
Y
E
R
Y
M
K
-
Y
L
T
G
C
A
K
L
F
R
V
G
Y
I
D
V
N
Q
F
T
L
A
K
---------------
21
PsiBlast_CBE
82.67
35%
-103
- C2 -
1L1E
2
CMAS3_MYCTU
B:
[16-285]
-----------------------------------------------------------------------------------------------------------------
Y
D
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
Y
F
E
R
D
D
M
T
L
Q
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
N
L
E
P
G
M
T
L
L
D
I
G
C
G
W
G
A
T
M
R
R
A
I
E
K
Y
D
V
N
V
V
G
L
T
L
S
E
N
Q
A
G
H
V
Q
K
M
F
D
Q
M
D
T
P
R
S
R
R
V
L
L
E
G
W
E
K
F
D
E
P
V
---
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
Q
R
-------
Y
H
H
F
F
E
V
T
H
R
T
L
P
A
D
G
K
M
L
L
H
T
I
V
R
P
T
-------------
F
K
---------------------------------LVH
F
T
K
--------
F
I
L
A
E
-------
I
F
P
G
G
W
L
P
S
I
P
T
V
H
E
Y
A
E
K
V
G
F
R
V
T
A
V
Q
S
L
Q
L
H
Y
A
R
T
L
D
M
W
A
T
A
L
E
A
N
K
D
Q
A
I
A
I
Q
S
Q
T
V
Y
D
R
Y
M
K
-
Y
L
T
G
C
A
K
L
F
R
Q
G
Y
T
D
V
D
Q
F
T
L
E
K
---------------
22
PsiBlast_CBE
82.52
34%
-99
- C2 -
1KPH
3
CMAS1_MYCTU
D:
[10-283]
-----------------------------------------------------------------------------------------------------------
A
N
V
Q
A
H
Y
D
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
Y
F
E
R
D
D
M
T
L
Q
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
G
L
Q
P
G
M
T
L
L
D
V
G
C
G
W
G
A
T
M
M
R
A
V
E
K
Y
D
V
N
V
V
G
L
T
L
S
K
N
Q
A
N
H
V
Q
Q
L
V
A
N
S
E
N
L
R
S
K
R
V
L
L
A
G
W
E
Q
F
D
E
P
V
---
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
E
R
-------
Y
D
A
F
F
S
L
A
H
R
L
L
P
A
D
G
V
M
L
L
H
T
I
T
--
G
-------------
L
H
P
------
K
E
--------------
I
-------
H
E
RGLPMSFTFARFLK
F
I
V
T
E
-------
I
F
P
G
G
R
L
P
S
I
P
M
V
Q
E
C
A
S
A
N
G
F
T
V
T
R
V
Q
S
L
Q
P
H
Y
A
K
T
L
D
L
W
S
A
A
L
Q
A
N
K
G
Q
A
I
A
L
Q
S
E
E
V
Y
E
R
Y
M
K
-
Y
L
T
G
C
A
E
M
F
R
I
G
Y
I
D
V
N
Q
F
T
C
Q
K
---------------
23
PsiBlast_CBE
82.25
34%
-98
- C2 -
1KPH
3
CMAS1_MYCTU
C:
[10-283]
-----------------------------------------------------------------------------------------------------------
A
N
V
Q
A
H
Y
D
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
Y
F
E
R
D
D
M
T
L
Q
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
G
L
Q
P
G
M
T
L
L
D
V
G
C
G
W
G
A
T
M
M
R
A
V
E
K
Y
D
V
N
V
V
G
L
T
L
S
K
N
Q
A
N
H
V
Q
Q
L
V
A
N
S
E
N
L
R
S
K
R
V
L
L
A
G
W
E
Q
F
D
E
P
V
---
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
E
R
-------
Y
D
A
F
F
S
L
A
H
R
L
L
P
A
D
G
V
M
L
L
H
T
I
T
--
G
-------------
L
H
P
------
K
E
--------------
I
-------
H
E
RGLPMSFTFARFLK
F
I
V
T
E
-------
I
F
P
G
G
R
L
P
S
I
P
M
V
Q
E
C
A
S
A
N
G
F
T
V
T
R
V
Q
S
L
Q
P
H
Y
A
K
T
L
D
L
W
S
A
A
L
Q
A
N
K
G
Q
A
I
A
L
Q
S
E
E
V
Y
E
R
Y
M
K
-
Y
L
T
G
C
A
E
M
F
R
I
G
Y
I
D
V
N
Q
F
T
C
Q
K
---------------
1
PsiBlast_PDB
81.98
34%
-95
- C2 -
1KPG
3
CMAS1_MYCTU
A:
[10-283]
-----------------------------------------------------------------------------------------------------------
A
N
V
Q
A
H
Y
D
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
Y
F
E
R
D
D
M
T
L
Q
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
G
L
Q
P
G
M
T
L
L
D
V
G
C
G
W
G
A
T
M
M
R
A
V
E
K
Y
D
V
N
V
V
G
L
T
L
S
K
N
Q
A
N
H
V
Q
Q
L
V
A
N
S
E
N
L
R
S
K
R
V
L
L
A
G
W
E
Q
F
D
E
P
V
---
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
E
R
-------
Y
D
A
F
F
S
L
A
H
R
L
L
P
A
D
G
V
M
L
L
H
T
I
T
--
G
-------------
L
H
P
------
K
E
--------------
I
-------
H
E
R
GLPM
S
F
T
F
A
R
F
L
K
F
I
V
T
E
-------
I
F
P
G
G
R
L
P
S
I
P
M
V
Q
E
C
A
S
A
N
G
F
T
V
T
R
V
Q
S
L
Q
P
H
Y
A
K
T
L
D
L
W
S
A
A
L
Q
A
N
K
G
Q
A
I
A
L
Q
S
E
E
V
Y
E
R
-
Y
M
K
Y
L
T
G
C
A
E
M
F
R
I
G
Y
I
D
V
N
Q
F
T
C
Q
K
---------------
24
PsiBlast_CBE
81.25
34%
-96
- C2 -
1KPH
3
CMAS1_MYCTU
B:
[10-283]
-----------------------------------------------------------------------------------------------------------
A
N
V
Q
A
H
Y
D
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
Y
F
E
R
D
D
M
T
L
Q
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
G
L
Q
P
G
M
T
L
L
D
V
G
C
G
W
G
A
T
M
M
R
A
V
E
K
Y
D
V
N
V
V
G
L
T
L
S
K
N
Q
A
N
H
V
Q
Q
L
V
A
N
S
E
N
L
R
S
K
R
V
L
L
A
G
W
E
Q
F
D
E
P
V
---
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
E
R
-------
Y
D
A
F
F
S
L
A
H
R
L
L
P
A
D
G
V
M
L
L
H
T
I
T
--
G
-------------
L
H
P
------
K
E
--------------
I
-------
H
E
R
GLPM
S
F
T
F
A
R
F
L
K
F
I
V
T
E
-------
I
F
P
G
G
R
L
P
S
I
P
M
V
Q
E
C
A
S
A
N
G
F
T
V
T
R
V
Q
S
L
Q
P
H
Y
A
K
T
L
D
L
W
S
A
A
L
Q
A
N
K
G
Q
A
I
A
L
Q
S
E
E
V
Y
E
R
Y
M
K
-
Y
L
T
G
C
A
E
M
F
R
I
G
Y
I
D
V
N
Q
F
T
C
Q
K
---------------
11
PsiBlast_PDB
81.24
31%
-91
* C2 *
1KPI
7
CMAS2_MYCTU
A:
[12-300]
---------------------------------------------------------------------------------------------------
Q
L
K
P
P
V
E
A
--
V
R
S
H
Y
D
K
S
N
E
F
F
K
L
W
L
D
P
S
M
T
Y
S
C
A
Y
F
E
R
P
D
M
T
L
E
E
A
Q
Y
A
K
R
K
L
A
L
D
K
L
N
L
E
P
G
M
T
L
L
D
I
G
C
G
W
G
S
T
M
R
H
A
V
A
E
Y
D
V
N
V
I
G
L
T
L
S
E
N
Q
Y
A
H
D
K
A
M
F
D
E
V
D
S
P
R
R
K
E
V
R
I
Q
G
W
E
E
F
D
E
P
V
---
D
R
I
V
S
L
G
A
F
E
H
FADGAGD
A
G
F
E
R
-------
Y
D
T
F
F
K
K
F
Y
N
L
T
P
D
D
G
R
M
L
L
H
T
I
T
--
I
-------------
P
D
K
E
E
A
Q
E
L
G
L
--------------
T
-------
S
P
M
S
L
L
R
F
I
K
------
F
I
L
T
E
-------
I
F
P
G
G
R
L
P
R
I
S
Q
V
D
Y
Y
S
S
N
A
G
W
K
V
E
R
Y
H
R
I
G
A
N
Y
V
P
T
L
N
A
W
A
D
A
L
Q
A
H
K
D
E
A
I
A
L
K
G
Q
E
T
-
C
D
I
Y
M
H
Y
L
R
G
C
S
D
L
F
R
D
K
Y
T
D
V
C
Q
F
T
L
V
K
---------------
2
PsiBlast_PDB
81.05
35%
-104
- C2 -
1L1E
2
CMAS3_MYCTU
A:
[16-285]
-----------------------------------------------------------------------------------------------------------------
Y
D
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
Y
F
E
R
D
D
M
T
L
Q
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
N
L
E
P
G
M
T
L
L
D
I
G
C
G
W
G
A
T
M
R
R
A
I
E
K
Y
D
V
N
V
V
G
L
T
L
S
E
N
Q
A
G
H
V
Q
K
M
F
D
Q
M
D
T
P
R
S
R
R
V
L
L
E
G
W
E
K
F
D
E
P
V
---
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
Q
R
-------
Y
H
H
F
F
E
V
T
H
R
T
L
P
A
D
G
K
M
L
L
H
T
I
V
R
P
T
-------------
F
K
E
------
G
R
--------------
E
-------
K
G
LTLTHEL
V
H
F
T
K
--
F
I
L
A
E
-------
I
F
P
G
G
W
L
P
S
I
P
T
V
H
E
Y
A
E
K
V
G
F
R
V
T
A
V
Q
S
L
Q
L
H
Y
A
R
T
L
D
M
W
A
T
A
L
E
A
N
K
D
Q
A
I
A
I
Q
S
Q
T
V
Y
D
R
Y
M
K
-
Y
L
T
G
C
A
K
L
F
R
Q
G
Y
T
D
V
D
Q
F
T
L
E
K
---------------
4
PsiBlast_PDB
81.00
34%
-97
- C2 -
1KPH
3
CMAS1_MYCTU
A:
[10-283]
-----------------------------------------------------------------------------------------------------------
A
N
V
Q
A
H
Y
D
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
Y
F
E
R
D
D
M
T
L
Q
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
G
L
Q
P
G
M
T
L
L
D
V
G
C
G
W
G
A
T
M
M
R
A
V
E
K
Y
D
V
N
V
V
G
L
T
L
S
K
N
Q
A
N
H
V
Q
Q
L
V
A
N
S
E
N
L
R
S
K
R
V
L
L
A
G
W
E
Q
F
D
E
P
V
---
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
E
R
-------
Y
D
A
F
F
S
L
A
H
R
L
L
P
A
D
G
V
M
L
L
H
T
I
T
--
G
-------------
L
H
P
------
K
E
--------------
I
-------
H
E
RGLPM
S
F
T
F
A
R
F
L
K
F
I
V
T
E
-------
I
F
P
G
G
R
L
P
S
I
P
M
V
Q
E
C
A
S
A
N
G
F
T
V
T
R
V
Q
S
L
Q
P
H
Y
A
K
T
L
D
L
W
S
A
A
L
Q
A
N
K
G
Q
A
I
A
L
Q
S
E
E
V
Y
E
R
Y
M
K
-
Y
L
T
G
C
A
E
M
F
R
I
G
Y
I
D
V
N
Q
F
T
C
Q
K
---------------
79
HHSearch
80.45
32%
-84
- C2 -
3HEM
2
CMAS2_MYCTU
A:
[13-302]
------------------------------------------------------------------------------------------------------
L
K
P
P
V
E
A
V
R
S
H
Y
D
K
S
N
E
F
F
K
L
W
L
D
P
S
M
T
Y
S
C
A
Y
F
E
R
P
D
M
T
L
E
E
A
Q
Y
A
K
R
K
L
A
L
D
K
L
N
L
E
P
G
M
T
L
L
D
I
G
C
G
W
G
S
T
M
R
H
A
V
A
E
Y
D
V
N
V
I
G
L
T
L
S
E
N
Q
Y
A
H
D
K
A
M
F
D
E
V
D
S
P
R
R
K
E
V
R
I
Q
G
W
E
E
F
D
E
---
P
V
D
R
I
V
S
L
G
A
F
E
H
-------
F
A
D
G
A
GDAGF
E
R
Y
D
T
F
F
K
K
F
Y
N
L
T
P
D
D
G
R
M
L
L
H
T
I
T
--
I
-------------
P
D
K
------
E
E
A
Q
E
L
G
L
T
S
P
M
S
L
L
R
F
-------
I
K
--------------
F
I
L
T
E
-------
I
F
P
G
G
R
L
P
R
I
S
Q
V
D
Y
Y
S
S
N
A
G
W
K
V
E
R
Y
H
R
I
G
A
N
Y
V
P
T
L
N
A
W
A
D
A
L
Q
A
H
K
D
E
A
I
A
L
-
K
G
Q
E
T
C
D
I
Y
M
H
Y
L
R
G
C
S
D
L
F
R
D
K
Y
T
D
V
C
Q
F
T
L
V
K
---------------
69
Fugue
80.05
35%
-95
- C2 -
1KPH
3
CMAS1_MYCTU
A:
[5-287]
---------------------------------------------------------------------
L
K
P
H
---------------------------------
F
A
N
V
Q
A
H
Y
D
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
Y
F
E
R
D
D
M
T
L
Q
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
G
L
Q
P
G
M
T
L
L
D
V
G
C
G
W
G
A
T
M
M
R
A
V
E
K
Y
D
V
N
V
V
G
L
T
L
S
K
N
Q
A
N
H
V
Q
Q
L
V
A
N
S
E
N
L
R
S
K
R
V
L
L
A
G
W
E
Q
F
D
E
P
---
V
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
E
R
-------
Y
D
A
F
F
S
L
A
H
R
L
L
P
A
D
G
V
M
L
L
H
T
I
T
--
G
-------------
L
H
P
------
K
E
--------------
I
-------
H
E
RGLPM
S
F
T
F
A
R
F
L
K
F
I
V
T
E
-------
I
F
P
G
G
R
L
P
S
I
P
M
V
Q
E
C
A
S
A
N
G
F
T
V
T
R
V
Q
S
L
Q
P
H
Y
A
K
T
L
D
L
W
S
A
A
L
Q
A
N
K
G
Q
A
I
A
L
Q
S
-
E
E
V
Y
E
R
Y
M
K
Y
L
T
G
C
A
E
M
F
R
I
G
Y
I
D
V
N
Q
F
T
C
Q
K
---------------
12
PsiBlast_PDB
79.99
31%
-88
- C2 -
3HEM
2
CMAS2_MYCTU
A:
[12-300]
---------------------------------------------------------------------------------------------------
Q
L
K
P
P
V
E
A
--
V
R
S
H
Y
D
K
S
N
E
F
F
K
L
W
L
D
P
S
M
T
Y
S
C
A
Y
F
E
R
P
D
M
T
L
E
E
A
Q
Y
A
K
R
K
L
A
L
D
K
L
N
L
E
P
G
M
T
L
L
D
I
G
C
G
W
G
S
T
M
R
H
A
V
A
E
Y
D
V
N
V
I
G
L
T
L
S
E
N
Q
Y
A
H
D
K
A
M
F
D
E
V
D
S
P
R
R
K
E
V
R
I
Q
G
W
E
E
F
D
E
P
V
---
D
R
I
V
S
L
G
A
F
E
H
FADGAGD
A
G
F
E
R
-------
Y
D
T
F
F
K
K
F
Y
N
L
T
P
D
D
G
R
M
L
L
H
T
I
T
--
I
-------------
P
D
K
E
E
A
Q
E
L
G
L
--------------
T
-------
S
P
M
S
L
L
R
F
I
K
------
F
I
L
T
E
-------
I
F
P
G
G
R
L
P
R
I
S
Q
V
D
Y
Y
S
S
N
A
G
W
K
V
E
R
Y
H
R
I
G
A
N
Y
V
P
T
L
N
A
W
A
D
A
L
Q
A
H
K
D
E
A
I
A
L
K
G
Q
E
T
-
C
D
I
Y
M
H
Y
L
R
G
C
S
D
L
F
R
D
K
Y
T
D
V
C
Q
F
T
L
V
K
---------------
78
HHSearch
79.68
31%
-97
- C2 -
2FK8
1
MMAA4_MYCTU
A:
[38-316]
-------------------------------------------------------------------------------------------------------------
I
Q
A
H
Y
D
V
S
D
D
F
F
A
L
F
Q
D
P
T
R
T
Y
S
C
A
Y
F
E
P
P
E
L
T
L
E
E
A
Q
Y
A
K
V
D
L
N
L
D
K
L
D
L
K
P
G
M
T
L
L
D
I
G
C
G
W
G
T
T
M
R
R
A
V
E
R
F
D
V
N
V
I
G
L
T
L
S
K
N
Q
H
A
R
C
E
Q
V
L
A
S
I
D
T
N
R
S
R
Q
V
L
L
Q
G
W
E
D
F
A
E
---
P
V
D
R
I
V
S
I
E
A
F
E
H
-------
F
G
H
E
N
-------
Y
D
D
F
F
K
R
C
F
N
I
M
P
A
D
G
R
M
T
V
Q
S
S
V
--
S
-------------
Y
H
P
------
Y
E
M
A
A
R
G
K
K
L
S
F
E
T
A
R
F
-------
I
K
--------------
F
I
V
T
E
-------
I
F
P
G
G
R
L
P
S
T
E
M
M
V
E
H
G
E
K
A
G
F
T
V
P
E
P
L
S
L
R
P
H
Y
I
K
T
L
R
I
W
G
D
T
L
Q
S
N
K
D
K
A
I
E
V
-
T
S
E
E
V
Y
N
R
Y
M
K
Y
L
R
G
C
E
H
Y
F
T
D
E
M
L
D
C
S
L
V
T
Y
L
K
P
G
A
A
A
----------
25
PsiBlast_CBE
79.51
34%
-95
- C2 -
1KP9
2
CMAS1_MYCTU
B:
[18-283]
-------------------------------------------------------------------------------------------------------------------
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
Y
F
E
R
D
D
M
T
L
Q
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
G
L
Q
P
G
M
T
L
L
D
V
G
C
G
W
G
A
T
M
M
R
A
V
E
K
Y
D
V
N
V
V
G
L
T
L
S
K
N
Q
A
N
H
V
Q
Q
L
V
A
N
S
E
N
L
R
S
K
R
V
L
L
A
G
W
E
Q
F
D
E
P
V
---
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
E
R
-------
Y
D
A
F
F
S
L
A
H
R
L
L
P
A
D
G
V
M
L
L
H
T
I
T
--
G
-------------
L
H
P
------
K
E
--------------
I
-------
H
E
RGLPMSFTFARFLK
F
I
V
T
E
-------
I
F
P
G
G
R
L
P
S
I
P
M
V
Q
E
C
A
S
A
N
G
F
T
V
T
R
V
Q
S
L
Q
P
H
Y
A
K
T
L
D
L
W
S
A
A
L
Q
A
N
K
G
Q
A
I
A
L
Q
S
E
E
V
Y
E
R
Y
M
K
-
Y
L
T
G
C
A
E
M
F
R
I
G
Y
I
D
V
N
Q
F
T
C
Q
K
---------------
70
Fugue
78.77
35%
-92
- C2 -
1KPH
3
CMAS1_MYCTU
A:
[5-287]
------------------------------------------------------------------------------------------------------
L
K
P
H
F
A
N
V
Q
A
H
Y
D
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
Y
F
E
R
D
D
M
T
L
Q
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
G
L
Q
P
G
M
T
L
L
D
V
G
C
G
W
G
A
T
M
M
R
A
V
E
K
Y
D
V
N
V
V
G
L
T
L
S
K
N
Q
A
N
H
V
Q
Q
L
V
A
N
S
E
N
L
R
S
K
R
V
L
L
A
G
W
E
Q
F
D
E
P
---
V
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
E
R
-------
Y
D
A
F
F
S
L
A
H
R
L
L
P
A
D
G
V
M
L
L
H
T
I
T
--
G
-------------
L
H
P
------
K
E
--------------
I
-------
H
E
RGLPM
S
F
T
F
A
R
F
L
K
F
I
V
T
E
-------
I
F
P
G
G
R
L
P
S
I
P
M
V
Q
E
C
A
S
A
N
G
F
T
V
T
R
V
Q
S
L
Q
P
H
Y
A
K
T
L
D
L
W
S
A
A
L
Q
A
N
K
G
Q
A
I
A
L
Q
-
S
E
E
V
Y
E
R
Y
M
K
Y
L
T
G
C
A
E
M
F
R
I
G
Y
I
D
V
N
Q
F
T
C
Q
K
---------------
3
PsiBlast_PDB
78.72
34%
-94
- C2 -
1KP9
1
CMAS1_MYCTU
A:
[18-283]
-------------------------------------------------------------------------------------------------------------------
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
Y
F
E
R
D
D
M
T
L
Q
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
G
L
Q
P
G
M
T
L
L
D
V
G
C
G
W
G
A
T
M
M
R
A
V
E
K
Y
D
V
N
V
V
G
L
T
L
S
K
N
Q
A
N
H
V
Q
Q
L
V
A
N
S
E
N
L
R
S
K
R
V
L
L
A
G
W
E
Q
F
D
E
P
V
---
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
E
R
-------
Y
D
A
F
F
S
L
A
H
R
L
L
P
A
D
G
V
M
L
L
H
T
I
T
--
G
-------------
L
H
P
------
K
E
--------------
I
-------
H
E
RGLPMS
F
T
F
A
R
F
L
K
F
I
V
T
E
-------
I
F
P
G
G
R
L
P
S
I
P
M
V
Q
E
C
A
S
A
N
G
F
T
V
T
R
V
Q
S
L
Q
P
H
Y
A
K
T
L
D
L
W
S
A
A
L
Q
A
N
K
G
Q
A
I
A
L
Q
S
E
E
V
Y
E
R
Y
M
K
-
Y
L
T
G
C
A
E
M
F
R
I
G
Y
I
D
V
N
Q
F
T
C
Q
K
---------------
6
PsiBlast_PDB
74.82
31%
-89
- C2 -
2FK7
-
MMAA4_MYCTU
A:
[22-282]
--------------------------------------------------------------------------------------------------------------
Q
A
H
Y
D
V
S
D
D
F
F
A
L
F
Q
D
P
T
R
T
Y
S
C
A
Y
F
E
P
P
E
L
T
L
E
E
A
Q
Y
A
K
V
D
L
N
L
D
K
L
D
L
K
P
G
M
T
L
L
D
I
G
C
G
W
G
T
T
M
R
R
A
V
E
R
F
D
V
N
V
I
G
L
T
L
S
K
N
Q
H
A
R
C
E
Q
V
L
A
S
I
D
T
N
R
S
R
Q
V
L
L
Q
G
W
E
D
F
A
E
P
V
---
D
R
I
V
S
I
E
A
F
E
H
----------
E
N
-------
Y
D
D
F
F
K
R
C
F
N
I
M
P
A
D
G
R
M
T
V
Q
S
S
V
--
S
Y
H
P
Y
E
M
A
A
R
G
K
K
L
S
F
E
T
-----
A
R
--------------
F
-------
I
K
--------------
F
I
V
T
E
-------
I
F
P
G
G
R
L
P
S
T
E
M
M
V
E
H
G
E
K
A
G
F
T
V
P
E
P
L
S
L
R
P
H
Y
I
K
T
L
R
I
W
G
D
T
L
Q
S
N
K
D
K
A
I
E
V
T
S
E
E
V
Y
N
R
-
Y
M
K
Y
L
R
G
C
E
H
Y
F
T
D
E
M
L
D
C
S
L
V
T
Y
L
K
P
G
A
A
A
----------
9
PsiBlast_PDB
74.20
31%
-91
- C2 -
3HA5
1
MMAA4_MYCTU
A:
[38-299]
-------------------------------------------------------------------------------------------------------------
I
Q
A
H
Y
D
V
S
D
D
F
F
A
L
F
Q
D
P
T
R
T
Y
S
C
A
Y
F
E
P
P
E
L
T
L
E
E
A
Q
Y
A
K
V
D
L
N
L
D
K
L
D
L
K
P
G
M
T
L
L
D
I
G
C
G
W
G
T
T
M
R
R
A
V
E
R
F
D
V
N
V
I
G
L
T
L
S
K
N
Q
H
A
R
C
E
Q
V
L
A
S
I
D
T
N
R
S
R
Q
V
L
L
Q
G
W
E
D
F
A
E
P
V
---
D
R
I
V
S
I
E
A
F
E
H
-------
F
G
H
E
N
-------
Y
D
D
F
F
K
R
C
F
N
I
M
P
A
D
G
R
M
T
V
Q
S
S
V
--
S
Y
H
P
Y
E
M
A
A
R
G
K
K
L
S
F
E
T
-----
A
R
--------------
F
-------
I
K
--------------
F
I
V
T
E
-------
I
F
P
G
G
R
L
P
S
T
E
M
M
V
E
H
G
E
K
A
G
F
T
V
P
E
P
L
S
L
R
P
H
Y
I
K
T
L
R
I
W
G
D
T
L
Q
S
N
K
D
K
A
I
E
V
T
S
E
E
V
Y
N
R
-
Y
M
K
Y
L
R
G
C
E
H
Y
F
T
D
E
M
L
D
C
S
L
V
T
Y
L
K
P
G
A
A
A
----------
8
PsiBlast_PDB
74.03
31%
-88
- C2 -
3HA3
1
MMAA4_MYCTU
A:
[38-299]
-------------------------------------------------------------------------------------------------------------
I
Q
A
H
Y
D
V
S
D
D
F
F
A
L
F
Q
D
P
T
R
T
Y
S
C
A
Y
F
E
P
P
E
L
T
L
E
E
A
Q
Y
A
K
V
D
L
N
L
D
K
L
D
L
K
P
G
M
T
L
L
D
I
G
C
G
W
G
T
T
M
R
R
A
V
E
R
F
D
V
N
V
I
G
L
T
L
S
K
N
Q
H
A
R
C
E
Q
V
L
A
S
I
D
T
N
R
S
R
Q
V
L
L
Q
G
W
E
D
F
A
E
P
V
---
D
R
I
V
S
I
E
A
F
E
H
-------
F
G
H
E
N
-------
Y
D
D
F
F
K
R
C
F
N
I
M
P
A
D
G
R
M
T
V
Q
S
S
V
--
S
Y
H
P
Y
E
M
A
A
R
G
K
K
L
S
F
E
T
-----
A
R
--------------
F
-------
I
K
--------------
F
I
V
T
E
-------
I
F
P
G
G
R
L
P
S
T
E
M
M
V
E
H
G
E
K
A
G
F
T
V
P
E
P
L
S
L
R
P
H
Y
I
K
T
L
R
I
W
G
D
T
L
Q
S
N
K
D
K
A
I
E
V
T
S
E
E
V
Y
N
R
-
Y
M
K
Y
L
R
G
C
E
H
Y
F
T
D
E
M
L
D
C
S
L
V
T
Y
L
K
P
G
A
A
A
----------