@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2541: (2016-04-04 )
MQTIHWNINKQQSNQAIFQEAAKLLQGGECVAFPTETVYGLGADATNQAAVQKIYEAKGRPSDNPLIVHIARREQMDQFVASYPAKAIQLMEKFWPGPLTVILPLKKDSLATNVSAGLSTVGVRMPEHPVSLALIGTANIPIAAPSANRSGKPSPTTASHVIEDLDGKIAGIIDGGATGVGLESTVIDCSLEIPIILRPGGVTKEQIEQIIGPVDISTNNTKETEKPKAPGMKYTHYAPKAPVYLIEGSTQFWQSEINKAEAANKKLGILATKELINQLNTSGTIETTGSIKALDEIATSLYKGLRAFDHADVDIIFAEVYPETELGAAIMNRLEKAAGNRRITE
Atome Classification :
(20 SA)
-------------------------------------------------------------------------------------.........10........20....-....30........40........50.-.......60.......-.70........80..--...-....90-...--.....--100.......110.-----------.-.....120--...-......130.......140......-..150..-.....160..-.....170.-.-.....180------------.........190--------------.......200.......210.-......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340...------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------M
Q
T
I
H
W
N
INKQQS
N
Q
A
I
F
Q
E
A
A
K
L
L-QGG
E
C
V
AFPTE
T
V
YGLGADA
T
N
Q
A
A
V
Q
-
K
I
Y
E
AKGRPSDN
P
L
I
V
-
H
I
A
R
R
E
Q
M
D
Q
F
V
-
A
S--Y
P
A
-
K
A
I
Q
L
M
-
E
K
F--WPG
P
L
--
T
V
I
L
PLKKDSLA
T
N
-----------
V
-SAG
L
S
T
----VGV-RMPEHP
V
S
L
A
L
I
GTANIP-IAAPSA-NRSGKPS-P
T
T
A
S
H
V
I
E
D-LDG
K
I
A
G
I
I-D-GGATGV--------------GL
E
S
T
V
I
D
C
S
L
E
--------------
I
P
I
I
L
RPGGV
T
K
E
Q
I
E
Q
I
IGP-VDISTNNTKETEKPKAPGMKYTHYAPKA
P
V
Y
L
IEG
S
T
Q
F
W
Q
S
EI
N
K
A
EAANKK
L
G
I
L
A
T
K
E
L
I
N
QLNTSG
T
I
ETTG
S
I
K
A
L
D
E
I
A
T
S
L
Y
K
G
L
R
A
FDHAD
V
D
I
I
F
A
EVYPE
T
E
L
G
A
A
I
M
N
R
L
E
K
AAGNRRITE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
99.61
42%
-101
* C5 *
2EQA
2
SUA5_SULTO
A:
[2-340]
---------------------------------------------------------------------------------------
T
Q
I
I
K
I
D
P
L
N
P
E
I
D
K
I
K
I
A
A
D
V
I
-
R
N
G
G
T
V
A
F
P
T
E
T
V
Y
G
L
G
A
N
A
F
D
G
N
A
C
L
-
K
I
F
Q
A
K
N
R
P
V
D
N
P
L
I
V
-
H
I
A
D
F
N
Q
L
F
E
V
A
-
K
D
--
I
P
D
-
K
V
L
E
I
A
-
Q
I
V
--
W
P
G
P
L
--
T
F
V
L
K
K
T
E
-
R
V
P
K
E
-----------
V
-
T
A
G
L
D
T
----
V
A
V
-
R
M
P
A
H
P
I
A
L
Q
L
I
R
E
S
G
V
P
-
I
A
A
P
S
A
-
N
L
A
T
R
P
S
-
P
T
K
A
E
D
V
I
V
D
-
L
N
G
R
V
D
V
I
I
-
D
-
G
G
H
T
F
F
--------------
G
V
E
S
T
I
I
N
V
T
V
E
--------------
P
-
V
L
L
R
P
G
P
F
T
I
E
E
L
K
K
L
F
G
E
I
V
I
------------------
Y
K
H
Y
A
P
N
T
R
L
L
L
V
E
N
R
N
I
F
K
D
V
-
V
S
-
L
L
S
K
K
Y
K
V
A
L
L
I
P
K
E
L
S
K
E
F
-
E
G
L
Q
Q
I
I
L
G
S
D
E
N
L
Y
E
V
A
R
N
L
F
D
S
F
R
E
L
D
K
L
N
V
D
L
G
I
M
I
G
F
P
E
R
G
I
G
F
A
I
M
N
R
A
R
K
A
S
G
F
S
I
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
97.18
43%
-97
- C5 -
3AJE
7
SUA5_SULTO
A:
[20-336]
---------------------------------------------------------------------------------------------------------
A
A
D
V
I
-
R
N
G
G
T
V
A
F
P
T
E
T
V
Y
G
L
G
A
N
A
F
D
G
N
A
C
L
-
K
I
F
Q
A
K
N
R
P
V
D
N
P
L
I
V
-
H
I
A
D
F
N
Q
L
F
E
V
A
-
K
D
--
I
P
D
-
K
V
L
E
I
A
-
Q
I
V
--
W
P
G
P
L
--
T
F
V
L
K
-
K
T
E
R
V
P
K
E
-----------
V
-
T
A
G
L
D
T
----
V
A
V
-
R
M
P
A
H
P
I
A
L
Q
L
I
R
E
S
G
V
P
-
I
A
A
P
S
A
-
N
L
A
T
R
P
S
-
P
T
K
A
E
D
V
I
V
D
-
L
N
G
R
V
D
V
I
I
-
D
-
G
G
H
T
F
F
--------------
G
V
E
S
T
I
I
N
V
T
V
E
--------------
P
P
V
L
L
R
P
G
P
F
T
I
E
E
L
K
K
L
F
G
E
-
I
V
I
P
------------------
H
Y
A
P
N
T
R
L
L
L
V
E
N
R
N
I
F
--
K
D
V
V
S
L
L
S
K
K
Y
K
V
A
L
L
I
P
K
E
L
S
K
E
F
E
G
L
Q
Q
I
-
I
L
G
S
D
E
N
L
Y
E
V
A
R
N
L
F
D
S
F
R
E
L
D
K
L
N
V
D
L
G
I
M
I
G
F
P
E
R
G
I
G
F
A
I
M
N
R
A
R
K
A
S
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
96.50
42%
-101
- C5 -
4E1B
2
SUA5_SULTO
A:
[20-336]
---------------------------------------------------------------------------------------------------------
A
A
D
V
I
-
R
N
G
G
T
V
A
F
P
T
E
T
V
Y
G
L
G
A
N
A
F
D
G
N
A
C
L
-
K
I
F
Q
A
K
N
R
P
V
D
N
P
L
I
V
-
H
I
A
D
F
N
Q
L
F
E
V
A
-
K
D
--
I
P
D
-
K
V
L
E
I
A
-
Q
I
V
--
W
P
G
P
L
--
T
F
V
L
K
-
K
T
E
R
V
P
K
E
-----------
V
-
T
A
G
L
D
T
----
V
A
V
-
R
M
P
A
H
P
I
A
L
Q
L
I
R
E
S
G
V
P
-
I
A
A
P
S
A
-
N
L
A
T
R
P
S
-
P
T
K
A
E
D
V
I
V
D
-
L
N
G
R
V
D
V
I
I
-
D
-
G
G
H
T
F
F
--------------
G
V
E
S
T
I
I
N
V
T
V
E
--------------
P
-
V
L
L
R
P
G
P
F
T
I
E
E
L
K
K
L
F
G
E
-
I
V
I
-----------------
Y
K
H
Y
A
P
N
T
R
L
L
L
V
E
N
R
N
I
F
--
K
D
V
V
S
L
L
S
K
K
Y
K
V
A
L
L
I
P
K
E
L
S
K
E
F
E
G
L
Q
Q
I
-
I
L
G
S
D
E
N
L
Y
E
V
A
R
N
L
F
D
S
F
R
E
L
D
K
L
N
V
D
L
G
I
M
I
G
F
P
E
R
G
I
G
F
A
I
M
N
R
A
R
K
A
S
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
94.55
42%
-102
- C5 -
2EQA
2
SUA5_SULTO
A:
[20-336]
---------------------------------------------------------------------------------------------------------
A
A
D
V
I
-
R
N
G
G
T
V
A
F
P
T
E
T
V
Y
G
L
G
A
N
A
F
D
G
N
A
C
L
-
K
I
F
Q
A
K
N
R
P
V
D
N
P
L
I
V
-
H
I
A
D
F
N
Q
L
F
E
V
A
-
K
D
--
I
P
D
-
K
V
L
E
I
A
-
Q
I
V
--
W
P
G
P
L
--
T
F
V
L
K
-
K
T
E
R
V
P
K
E
-----------
V
-
T
A
G
L
D
T
----
V
A
V
-
R
M
P
A
H
P
I
A
L
Q
L
I
R
E
S
G
V
P
-
I
A
A
P
S
A
-
N
L
A
T
R
P
S
-
P
T
K
A
E
D
V
I
V
D
-
L
N
G
R
V
D
V
I
I
-
D
-
G
G
H
T
F
F
--------------
G
V
E
S
T
I
I
N
V
T
V
E
--------------
P
-
V
L
L
R
P
G
P
F
T
I
E
E
L
K
K
L
F
G
E
-
I
V
I
-----------------
Y
K
H
Y
A
P
N
T
R
L
L
L
V
E
N
R
N
I
F
--
K
D
V
V
S
L
L
S
K
K
Y
K
V
A
L
L
I
P
K
E
L
S
K
E
F
E
G
L
Q
Q
I
-
I
L
G
S
D
E
N
L
Y
E
V
A
R
N
L
F
D
S
F
R
E
L
D
K
L
N
V
D
L
G
I
M
I
G
F
P
E
R
G
I
G
F
A
I
M
N
R
A
R
K
A
S
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
68.64
21%
-99
- C5 -
1K7J
1
YCIO_ECOLI
A:
[2-205]
---------------------------------------------------------------------------------------
S
Q
F
F
Y
I
H
P
D
N
P
Q
Q
R
L
I
N
Q
A
V
E
I
V
-
R
K
G
G
V
I
V
Y
P
T
D
S
G
Y
A
L
G
C
K
I
E
D
K
N
A
M
E
-
R
I
C
R
I
R
Q
L
P
D
G
H
N
F
T
L
-
M
C
R
D
L
S
E
L
S
T
Y
S
-
F
---
V
D
N
-
V
A
F
R
L
M
-
K
N
N
--
T
P
G
N
Y
--
T
F
I
L
K
G
T
K
-
E
V
P
R
R
-----------
L
L
Q
E
K
R
K
T
----
I
G
M
-
R
V
P
S
N
P
I
A
Q
A
L
L
E
A
L
G
E
P
-
M
L
S
T
S
L
-
M
L
P
G
S
E
F
T
E
S
D
P
E
E
I
K
D
R
-
L
E
K
Q
V
D
L
I
I
-
H
-
G
G
Y
L
-
G
--------------
Q
K
P
T
T
V
I
D
L
T
D
D
--------------
T
P
V
V
V
R
E
G
V
G
D
V
K
P
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
65.49
26%
-105
- C5 -
1HRU
1
TSAC_ECOLI
A:
[3-188]
-----------------------------------------------------------------------------------------------
N
N
L
Q
R
D
A
I
A
A
A
I
D
V
L
-
N
E
E
R
V
I
A
Y
P
T
E
A
V
F
G
V
G
C
D
P
D
S
E
T
A
V
M
-
R
L
L
E
L
K
Q
R
P
V
D
K
G
L
I
L
-
I
A
A
N
Y
E
Q
L
K
P
Y
I
-
D
D
TM
L
T
D
-
V
Q
R
E
T
I
-
F
S
R
--
W
P
G
P
V
--
T
F
V
F
P
A
P
A
-
T
T
P
R
W
-----------
L
-
T
G
R
F
D
S
----
L
A
V
-
R
V
T
D
H
P
L
V
V
A
L
C
Q
A
Y
G
K
P
-
L
V
S
T
S
A
-
N
L
S
G
L
P
P
-
C
R
T
V
D
E
V
R
A
Q
-
F
G
A
A
F
P
-
V
V
-
P
-
G
E
T
G
G
R
--------------
L
N
P
S
E
I
R
D
A
L
T
G
----------------
E
L
F
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
64.25
22%
-84
- C5 -
1KK9
1
YCIO_ECOLI
A:
[20-213]
------------------------------------------------------------------------------------------
F
Y
I
H
P
D
N
P
Q
Q
R
L
I
N
Q
A
V
E
I
V
-
R
K
G
G
V
I
V
Y
P
T
D
S
G
Y
A
L
G
C
K
I
E
D
K
N
A
M
E
-
R
I
C
R
I
R
Q
L
P
D
G
H
N
F
T
L
-
M
C
R
D
L
S
E
L
S
T
Y
--
S
F
--
V
D
N
-
V
A
F
R
L
M
-
K
N
N
--
T
P
G
N
Y
--
T
F
I
L
K
G
T
K
E
V
P
R
R
L
-----------
L
-
Q
E
K
R
K
T
----
I
G
M
-
R
V
P
S
N
P
I
A
Q
A
L
L
E
A
L
G
E
P
-
M
L
S
T
S
L
-
M
L
P
G
S
E
F
-
T
E
S
D
P
E
E
I
K
D
R
L
E
K
Q
V
D
L
I
I
-
H
-
G
G
Y
L
G
Q
--------------
K
-
P
T
T
V
I
D
L
T
D
D
--------------
T
P
V
V
V
R
E
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
63.97
31%
-94
- C5 -
1JCU
-
?
A:
[1-208]
--------------------------------------------------------------------------------------
M
L
I
R
K
I
T
R
K
N
P
S
-
P
D
V
L
E
E
A
I
S
V
M
-
E
G
G
G
I
V
I
Y
P
T
D
T
I
Y
G
L
G
V
N
A
L
D
E
D
A
V
R
-
R
L
F
R
V
K
G
R
S
P
H
K
P
V
S
I
-
C
V
S
C
V
D
E
I
P
R
F
S
R
P
S
----
G
-
D
A
M
E
L
M
-
E
R
I
--
L
P
G
P
Y
--
T
V
V
L
E
R
N
E
-
L
I
P
D
V
-----------
I
-
T
G
G
S
S
R
----
V
G
I
-
R
V
P
D
D
E
I
C
R
R
I
A
A
R
--
F
P
-
V
T
A
T
S
A
-
N
I
S
G
K
P
P
-
S
P
R
L
E
E
I
V
R
D
-
L
D
A
V
D
L
-
V
L
-
D
-
A
G
D
C
L
D
--------------
M
E
P
S
T
V
I
D
L
T
V
N
--------------
P
P
R
V
L
R
R
G
K
G
P
L
D
P
V
-
L
L
R
G
A
-
G
D
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
63.41
18%
-77
- C5 -
1K7J
1
YCIO_ECOLI
A:
[2-206]
---------------------------------------------------------------------------------------
S
Q
F
F
Y
I
H
P
D
N
P
Q
Q
R
L
I
N
Q
A
V
E
I
V
-
R
K
G
G
V
I
V
Y
P
T
D
S
G
Y
A
L
G
C
K
I
E
D
K
N
A
M
E
-
R
I
C
R
I
R
Q
L
P
D
G
H
N
F
T
L
M
C
-
R
D
L
S
E
L
S
T
Y
S
-----
F
V
D
-
N
V
A
F
R
L
M
K
N
N
--
T
P
G
N
Y
--
T
F
I
L
K
-
G
T
K
E
V
P
R
R
-----------
L
-
L
Q
E
K
R
K
----
T
I
G
M
R
V
P
S
N
P
I
A
Q
A
L
L
E
A
L
G
E
P
M
L
-
S
T
S
L
M
L
P
G
S
E
F
T
-
E
S
D
P
E
E
I
K
D
R
-
L
E
K
Q
V
D
L
I
I
-
H
-
G
G
Y
L
G
Q
--------------
K
-
P
T
T
V
I
D
L
T
D
D
--------------
T
P
V
V
V
R
E
G
V
G
D
V
K
P
F
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
62.68
25%
-101
- C5 -
1HRU
1
TSAC_ECOLI
A:
[3-188]
-----------------------------------------------------------------------------------------------
N
N
L
Q
R
D
A
I
A
A
A
I
D
V
L
-
N
E
E
R
V
I
A
Y
P
T
E
A
V
F
G
V
G
C
D
P
D
S
E
T
A
V
-
M
R
L
L
E
L
K
Q
R
P
V
D
K
G
L
I
L
-
I
A
A
N
Y
E
Q
L
K
P
Y
I
D
D
T
M-
L
T
D
-
V
Q
R
E
T
I
-
F
S
R
--
W
P
G
P
V
--
T
F
V
F
P
-
A
P
A
T
T
P
R
W
-----------
L
-
T
G
R
F
D
S
----
L
A
V
-
R
V
T
D
H
P
L
V
V
A
L
C
Q
A
Y
G
K
P
-
L
V
S
T
S
A
-
N
L
S
G
L
P
P
-
C
R
T
V
D
E
V
R
A
Q
-
F
G
A
A
F
-
P
V
V
-
P
-
G
E
T
G
G
R
--------------
L
N
P
S
E
I
R
D
A
L
T
G
--------------
E
L
F
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
62.18
22%
-81
- C5 -
1K7J
1
YCIO_ECOLI
A:
[5-198]
------------------------------------------------------------------------------------------
F
Y
I
H
P
D
N
P
Q
Q
R
L
I
N
Q
A
V
E
I
V
-
R
K
G
G
V
I
V
Y
P
T
D
S
G
Y
A
L
G
C
K
I
E
D
K
N
A
M
E
-
R
I
C
R
I
R
Q
L
P
D
G
H
N
F
T
L
-
M
C
R
D
L
S
E
L
S
T
Y
--
S
F
--
V
D
N
-
V
A
F
R
L
M
-
K
N
N
--
T
P
G
N
Y
--
T
F
I
L
K
G
T
K
E
V
P
R
R
L
-----------
L
-
Q
E
K
R
K
T
----
I
G
M
-
R
V
P
S
N
P
I
A
Q
A
L
L
E
A
L
G
E
P
-
M
L
S
T
S
L
-
M
L
P
G
S
E
F
-
T
E
S
D
P
E
E
I
K
D
R
L
E
K
Q
V
D
L
I
I
-
H
-
G
G
Y
L
G
Q
--------------
K
-
P
T
T
V
I
D
L
T
D
D
--------------
T
P
V
V
V
R
E
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
59.92
19%
-52
- C5 -
3TTC
6
?
A:
[12-657]
QIVPDAATC
P
A
C
L
A
E
M
N
TPGERRYRYPFINCTHCGPRFTIIRAMPYDRPFTVMAA
F
P
L
C
P
A
C
D
K
E
Y
R
DPLDRRFHAQPVACPEC
G
P
Y
L
E
W
V
S
H
G
E
H
A
E
Q
E
A
A
L
Q
A
A
I
A
Q
L
-
K
M
G
N
I
V
A
I
K
G
I
G
G
F
H
L
A
C
D
A
R
N
S
N
A
V
A
-
T
L
R
A
R
K
H
R
P
-
A
K
P
L
A
V
-
M
L
P
V
A
D
G
L
P
---------
D
A
-
A
R
Q
L
L
T
-
T
P
----
A
A
P
I
--
V
L
V
D
K
K
Y
V
P
E
L
C
D
D
-----------
I
-
A
P
G
L
N
E
----
V
G
V
-
M
L
P
A
N
P
L
Q
H
L
L
L
Q
E
L
Q
C
P
-
L
V
M
T
S
G
-
N
L
S
G
K
P
P
-
A
I
S
N
E
Q
A
L
E
D
-
L
Q
G
I
----------
A
D
G
F
--------------
L
I
H
N
R
D
I
V
Q
R
M
D
--------------
D
S
V
V
R
E
S
G
E
M
L
R
R
S
R
G
Y
V
P
D
A
-
L
A
L
P
P
G
F
------
K
N
V
P
P
V
L
C
L
G
A
D
L
K
N
T
F
C
L
V
R
G
E
Q
V
V
L
S
Q
H
L
-------------------------
G
D
L
S
D
D
G
I
Q
T
Q
W
R
E
A
L
R
L
M
Q
N
I
Y
N
F
----
T
P
Q
Y
V
V
H
D
A
H
P
G
--------
Y
V
S
C
Q
W
A
S
E
M
N
L
P
T
Q
T
V
L
H
H
H
A
H
A
A
A
C
L
A
E
H
QWPLDG
G
D
V
I
A
L
T
L
D
G
I
G
M
G
E
NG
A
L
W
G
GECLRVNYR
E
C
E
H
L
G
GLPAVALPG
G
D
L
A
A
K
Q
P
W
R
N
L
L
A
Q
C
L
R
FVPEWQNYPET
A
S
V
A
A
ANW
S
V
L
A
R
A
I
E
R
GIN
A
P
L
A
SS
C
G
R
L
F
D
A
V
A
A
A
L
GCAPATLSYEG
E
A
A
C
A
L
E
A
L
A
A
S
CD
G
V
T
H
PVTMPRVDNQLD
L
A
T
F
W
Q
Q
W
L
N
WQAP
V
N
Q
R
A
W
A
F
H
D
A
L
A
Q
G
F
A
A
L
M
R
E
Q
A
T
M
R
GIT
T
L
V
F
S
G
GVIHN
R
L
L
R
A
R
L
A
H
Y
L
AD
F
T
L
L
F
P
Q
SLPAGDGG
L
S
L
G
Q
G
V
I
A
A
A
R
W
L
A
GE
26
HHSearch
58.93
26%
-73
- C5 -
3TTC
2
?
A:
[110-292]
--------------------------------------------------------------------------------------------------
Q
E
A
A
L
Q
A
A
I
A
Q
L
-
K
M
G
N
I
V
A
I
K
G
I
G
G
F
H
L
A
C
D
A
R
N
S
N
A
V
A
-
T
L
R
A
R
K
H
R
P
-
A
K
P
L
A
V
-
M
L
P
V
A
D
G
L
P
----------
D
-
A
A
R
Q
L
L
-
T
T
---
P
A
A
P
I
--
V
L
V
D
K
K
Y
V
P
E
L
C
D
D
-----------
I
-
A
P
G
L
N
E
----
V
G
V
-
M
L
P
A
N
P
L
Q
H
L
L
L
Q
E
L
Q
C
P
-
L
V
M
T
S
G
-
N
L
S
G
K
P
P
-
A
I
S
N
E
Q
A
L
E
D
-
L
Q
G
I
A
D
G
F
L
I
H
-
N
R
D
I
V
Q
--------------
R
M
D
D
S
V
V
R
E
S
G
-----------------
E
M
L
R
R
S
R
G
Y
V
P
D
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
58.37
33%
-80
- C5 -
1JCU
-
?
A:
[6-193]
--------------------------------------------------------------------------------------------
I
T
R
K
N
P
S
P
D
V
L
E
E
A
I
S
V
M
-
E
G
G
G
I
V
I
Y
P
T
D
T
I
Y
G
L
G
V
N
A
L
D
E
D
A
V
R
-
R
L
F
R
V
K
G
R
S
P
H
K
P
V
S
I
-
C
V
S
C
V
D
E
I
P
R
F
---
S
--
R
P
S
G
D
A
M
E
L
M
-
E
R
I
--
L
P
G
P
Y
--
T
V
V
--
L
E
R
N
E
L
I
P
D
-----------
V
I
T
G
G
S
S
R
----
V
G
I
-
R
V
P
D
D
E
I
C
R
R
I
--
A
A
R
F
P
-
V
T
A
T
S
A
-
N
I
S
G
K
P
P
-
S
P
R
L
E
E
I
V
R
D
-
L
D
A
-
V
D
L
V
L
-
D
-
A
G
D
C
L
D
--------------
M
E
P
S
T
V
I
D
L
T
V
N
--------------
P
P
R
V
L
R
R
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
58.01
20%
-80
- C5 -
3VTH
4
?
A:
[201-390]
--------------------------------------------------------------------------------------------------
F
D
D
E
I
K
C
V
A
K
A
L
-
K
E
G
K
I
V
A
I
K
G
I
G
G
F
H
L
A
V
N
A
L
D
D
E
A
V
A
-
T
L
R
R
R
K
K
R
Y
-
G
K
P
F
A
V
-
M
M
R
D
V
E
E
V
K
K
Y
C
-
I
---
V
S
P
-
E
E
E
R
L
L
-
L
S
---
Q
R
R
P
I
--
V
L
L
K
K
K
G
E
-
K
L
A
K
G
-----------
I
-
A
D
D
L
D
T
----
L
G
V
-
M
L
P
Y
A
P
I
H
Y
L
L
M
E
E
I
D
F
P
-
I
V
M
T
S
G
-
N
V
S
E
E
P
I
-
C
K
D
N
E
E
A
L
E
K
-
L
K
D
I
A
D
V
F
L
-
L
N
N
R
D
I
V
N
--------------
R
I
D
D
S
V
T
S
F
N
A
G
--------------
A
E
R
I
I
R
R
A
R
G
Y
A
P
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
54.05
18%
-87
- C5 -
3L7V
7
?
A:
[41-282]
-------------------------------------------------------------------------------------------------
W
D
G
N
L
S
Q
E
G
F
E
I
V
K
G
E
G
G
V
I
V
C
P
T
K
V
G
Y
I
I
M
T
--
S
D
K
K
G
L
E
-
R
K
F
E
A
K
K
R
N
R
N
K
P
G
V
V
-
L
C
G
S
M
E
E
L
R
A
L
A
-
Q
---
L
T
P
-
E
I
D
A
F
Y
-
Q
K
H
--
W
D
E
D
I
L
L
G
C
I
L
P
W
K
A
-
E
A
Y
E
K
L
K
AYGDGREEL
M
-
T
D
I
R
G
T
S
C
F
V
I
K
F
-
G
V
A
G
E
Q
I
A
K
E
M
W
E
K
E
G
R
M
-
V
Y
A
S
S
A
-
N
-----
N
-
R
G
K
V
E
G
I
G
E
R
-
I
E
S
M
V
D
L
V
I
-
E
-
A
D
D
Y
V
A
S
I
Q
PDKTIETRYE
Q
G
V
M
V
S
M
V
D
K
D
G
K
L
I
P
QQGADSRSVEP
C
P
V
V
I
R
K
G
L
-
D
I
D
K
I
M
M
H
L
S
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
53.22
26%
-85
- C5 -
3VTI
-
?
A:
[208-348]
---------------------------------------------------------------------------------------------------------
V
A
K
A
L
-
K
E
G
K
I
V
A
I
K
G
I
G
G
F
H
L
A
V
N
A
L
D
D
E
A
V
A
-
T
L
R
R
R
K
K
R
Y
G
-
K
P
F
A
V
-
M
M
R
D
V
E
E
V
K
K
Y
C
-
I
V
--
S
P
E
-
E
E
R
L
L
L
-
S
Q
R
--
R
P
-----
I
V
L
L
K
K
K
G
E
K
L
A
K
G
-----------
I
-
A
D
D
L
D
T
----
L
G
V
-
M
L
P
Y
A
P
I
H
Y
L
L
M
E
E
I
D
F
P
-
I
V
M
T
S
G
-
N
V
S
E
E
P
I
-
C
K
D
N
E
E
A
L
E
K
-
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
52.18
26%
-85
- C5 -
3VTH
4
?
A:
[208-348]
---------------------------------------------------------------------------------------------------------
V
A
K
A
L
-
K
E
G
K
I
V
A
I
K
G
I
G
G
F
H
L
A
V
N
A
L
D
D
E
A
V
A
-
T
L
R
R
R
K
K
R
Y
G
-
K
P
F
A
V
-
M
M
R
D
V
E
E
V
K
K
Y
C
-
I
V
--
S
P
E
-
E
E
R
L
L
L
-
S
Q
R
--
R
P
-----
I
V
L
L
K
K
K
G
E
K
L
A
K
G
-----------
I
-
A
D
D
L
D
T
----
L
G
V
-
M
L
P
Y
A
P
I
H
Y
L
L
M
E
E
I
D
F
P
-
I
V
M
T
S
G
-
N
V
S
E
E
P
I
-
C
K
D
N
E
E
A
L
E
K
-
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
51.80
31%
-90
- C5 -
1HRU
1
TSAC_ECOLI
A:
[13-154]
---------------------------------------------------------------------------------------------------------
A
I
D
V
L
-
N
E
E
R
V
I
A
Y
P
T
E
A
V
F
G
V
G
C
D
P
D
S
E
T
A
V
M
-
R
L
L
E
L
K
Q
R
P
V
D
K
G
L
I
L
-
I
A
A
N
Y
E
Q
L
K
P
Y
I
-
D
D
--
T
M
L
-
T
D
V
Q
R
E
-
T
I
F
S
R
W
P
G
P
V
--
T
F
V
F
P
A
P
A
-
T
T
P
R
W
-----------
L
-
T
G
R
F
D
S
----
L
A
V
-
R
V
T
D
H
P
L
V
V
A
L
C
Q
A
Y
G
K
P
-
L
V
S
T
S
A
-
N
L
S
G
L
P
P
-
C
R
T
V
D
E
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
45.21
28%
-70
- C5 -
3TTC
2
?
A:
[135-260]
----------------------------------------------------------------------------------------------------------------------------
F
H
L
A
C
D
A
R
N
S
N
A
V
A
-
T
L
R
A
R
K
H
R
P
A
-
K
P
L
A
V
-
M
L
P
V
A
D
G
L
----------
P
D
-
A
A
R
Q
L
L
-
T
T
P
---
A
A
P
I
--
V
L
V
D
K
K
Y
V
P
E
L
C
D
D
-----------
I
-
A
P
G
L
N
E
----
V
G
V
-
M
L
P
A
N
P
L
Q
H
L
L
L
Q
E
L
Q
C
P
-
L
V
M
T
S
G
-
N
L
S
G
K
P
P
-
A
I
S
N
E
Q
A
L
E
D
-
L
Q
G
I
A
D
G
F
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------