@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1401: (2015-12-07 )
MFNIFKRLNGKEWLMIVASTILVCLAVWMDLKTPEYMSDITRMLQTKGTKLEALWDPGLKMLAFSFGSFLVAVMVGFLGARTAASFTSRLRSDIFNHVMDYSDAEIKRFSIPSLLTRTTNDLTQLQILIVMGMQVVTRGPIMAIWALTKIWGKSDQWTGAVGVAVIIVMILLSVLLLLAFPRQRQIQGFTDALNATTREALSGVRVIRAYNAEKYQTDKFKRENDDLTKLNLFVYRLMSLMNPVMTVVSSGLTLAIYWIGSYLINDISVPKVTGTSVSVLAAKSAITDRVDLFSNMVVFSSYAMQVVMGFMMMVAIFIIMPRALVSARRINEVLTLAPTVTFKENSHIQSAQKGQIEFQDVSFHYSKDSEAVIEHVSFKADTGQTVAFIGSTGSGKSTLVNLVTRFYDATEGAIKLDGIDIKEYSHNDLNNKIGYIPQKAVLFSGTVRSNMILGESGREELSDEEIWQALELAQAKEFIEAKEKGLDTEVAQGGSNFSGGQKQRLAIARALARHPEILIFDDSFSALDYKTDHILRHELKEKTAAMTKLIVAQRISTIMDADLILVLDQGKVVGQGTHKELLSNNEVYQEIAYSQLSKEELENEN
Atome Classification :
(25 SA)
-----------------------------------------------------------------------------.........10......---..20........30........40.......----.-50-.......----..60........70...--.....80........-----90........100.......110.......120....----...130.......140.......150.......160.......170.......----180.---------.-----..----...190.......200....-...210.......220.....-------..230.......240..-.....250....-...260.......270...-....280.......290.......300.......310.......320--........330.......340...----.-...350----.......360...-...-.-370.......380.......390.......400.......410-.---........420.......430.......440.......450.......-460-.........470.......480.......490.......500.......510.......520.......530.......540.--..--....550.......560.......570.......580-...--.....590.......600...-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------M
F
N
I
F
K
RLNGKE
W
L
M
I
V
---
A
S
T
I
L
V
C
L
A
V
W
MDLK
T
P
E
Y
M
S
D
I
T
R
M
L
Q
TKG----
T
-
K
--
L
E
A
LWDP----
G
L
K
M
L
A
F
S
F
G
S
F
L
V
A
V
M
--
V
G
F
LG
A
R
T
A
A
S
F
T
S
R
-----
L
R
S
D
I
F
N
H
V
MDYSDAE
I
K
RFS
I
P
S
L
L
T
RTTN
D
L
T
Q
L
Q
----
I
L
I
V
MG
M
Q
V
VTRGP
I
M
A
I
W
A
L
T
K
I
WGKSDQWT
G
A
V
G
V
A
V
I
I
V
M
I
L
L
S
V
L
L
L
LA----FPRQ---------R-----QI----
Q
G
F
T
D
A
L
N
A
T
T
R
E
A
L
S
G
V
R
V
-
I
R
AYNAEKYQTDKFKRENDD
L
-------
T
K
L
N
L
F
V
Y
R
L
M
S
L
M
N
P
V
-
M
T
V
V
SSG
L
T
L
A
I
-
Y
W
I
G
S
Y
L
I
NDISVPKVTG
T
-
S
V
S
V
L
A
A
K
S
A
I
T
D
R
V
D
L
F
S
N
M
V
V
F
S
S
Y
A
M
Q
V
V
M
G
F
M
M
M
V
A
I
F
I
I
M
P
---
R
A
L
V
S
A
R
R
I
N
E
V
L
TLA
P
T
V
T
FKEN----S-HIQSAQ----KG
Q
I
E
F
Q
D
V
S
F
H
Y-SK
D
-
S
-
E
A
V
I
E
H
VSFKADTG
Q
T
V
A
F
I
GSTGS
G
K
S
T
L
V
N
L
V
T
R
F
Y
DAT---E---
G
A
I
K
LD
G
I
D
I
K
EYSHNDLNNKIGYIPQ
K
A
V
L
F
SGTVRS
N
M
I
LGESGRE-E---L
S
D
E
E
I
W
Q
A
L
E
L
A
Q
A
K
E
F
I
E
A
K
EKGLD
T
E
V
AQGGSNFSG
G
Q
K
Q
R
L
A
I
A
R
A
L
ARHP
E
I
L
I
FDDSFSALDY
K
T
D
H
I
L
R
H
E
L
K
E
K
T
--
A
A
--
M
T
K
L
I
V
A
Q
R
I
S
T
IMDA
D
L
I
L
V
L
DQG
K
V
VGQG
T
H
K
E
L
--LSN--
N
E
V
Y
Q
E
I
A
Y
S
Q
L
S
K
E
E
LENEN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
89.37
33%
-105
- C1 -
4Q4A
2
?
A:
[22-579]
-----------------------------------------------------------------------------------------
W
I
F
A
V
---
L
A
P
L
F
M
V
V
E
V
I
C
D
L
S
Q
P
T
L
L
A
R
I
V
D
E
G
I
A
R
G
------
D
--
F
S
L
V
L
K
T
----
G
I
L
M
L
-------
I
V
A
L
I
G
A
V
G
G
I
G
C
T
V
F
A
S
Y
A
S
Q
N
F
G
A
D
L
R
R
D
L
F
R
K
V
L
S
F
S
I
S
N
V
N
R
F
H
T
S
S
L
I
T
R
L
T
N
D
V
T
Q
L
Q
----
N
L
V
M
M
L
L
R
I
V
V
R
A
P
L
L
F
V
G
G
I
V
M
A
V
S
I
N
V
K
L
S
S
V
L
I
F
L
I
P
P
I
V
L
L
F
V
W
L
T
K
K
G
----
N
P
L
F
---------
R
-----
K
I
----
Q
E
S
T
D
E
V
N
R
V
V
R
E
N
L
L
G
V
R
V
-
V
R
A
F
R
R
E
E
Y
E
N
E
N
F
R
K
A
N
E
S
L
-------
R
R
S
I
I
S
A
F
S
L
I
V
F
A
L
P
L
-
F
I
F
I
V
N
M
G
M
I
A
V
-
L
W
F
G
G
V
L
V
R
N
----------------------
N
Q
M
E
I
G
S
I
M
A
-
Y
T
N
Y
L
M
Q
I
M
F
S
L
M
M
I
G
N
I
L
N
F
I
V
---
R
A
S
A
S
A
K
R
V
L
E
V
L
N
E
K
P
A
I
E
E
A
D
N
----
A
-
L
A
L
P
N
V
----
E
G
S
V
S
F
E
N
V
E
F
R
Y
-
F
E
N
-
T
-
D
P
V
L
S
G
V
N
F
S
V
K
P
G
S
L
V
A
V
L
G
E
T
G
S
G
K
S
T
L
M
N
L
I
P
R
L
I
D
P
E
---
R
---
G
R
V
E
V
D
E
L
D
V
R
T
V
K
L
K
D
L
R
G
H
I
S
A
V
P
Q
E
T
V
L
F
S
G
T
I
K
E
N
L
---
K
W
G
R
E
-
D
---
A
T
D
D
E
I
V
E
A
A
K
I
A
Q
I
H
D
F
I
I
S
L
P
E
G
Y
D
S
R
V
E
R
G
G
R
N
F
S
G
G
Q
K
Q
R
L
S
I
A
R
A
L
V
K
K
P
K
V
L
I
L
D
D
C
T
S
S
V
D
P
I
T
E
K
R
I
L
D
G
L
K
R
Y
T
--
K
G
--
C
T
T
F
I
I
T
Q
K
I
P
T
A
L
L
A
D
K
I
L
V
L
H
E
G
K
V
A
G
F
G
T
H
K
E
L
--
L
E
H
--
C
K
P
Y
R
E
I
Y
E
S
Q
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
88.89
33%
-106
- C1 -
3QF4
2
?
A:
[22-579]
-----------------------------------------------------------------------------------------
W
I
F
A
V
---
L
A
P
L
F
M
V
V
E
V
I
C
D
L
S
Q
P
T
L
L
A
R
I
V
D
E
G
I
A
R
G
------
D
--
F
S
L
V
L
K
T
----
G
I
L
M
L
-------
I
V
A
L
I
G
A
V
G
G
I
G
C
T
V
F
A
S
Y
A
S
Q
N
F
G
A
D
L
R
R
D
L
F
R
K
V
L
S
F
S
I
S
N
V
N
R
F
H
T
S
S
L
I
T
R
L
T
N
D
V
T
Q
L
Q
----
N
L
V
M
M
L
L
R
I
V
V
R
A
P
L
L
F
V
G
G
I
V
M
A
V
S
I
N
V
K
L
S
S
V
L
I
F
L
I
P
P
I
V
L
L
F
V
W
L
T
K
K
G
----
N
P
L
F
---------
R
-----
K
I
----
Q
E
S
T
D
E
V
N
R
V
V
R
E
N
L
L
G
V
R
V
-
V
R
A
F
R
R
E
E
Y
E
N
E
N
F
R
K
A
N
E
S
L
-------
R
R
S
I
I
S
A
F
S
L
I
V
F
A
L
P
L
-
F
I
F
I
V
N
M
G
M
I
A
V
-
L
W
F
G
G
V
L
V
R
N
----------------------
N
Q
M
E
I
G
S
I
M
A
-
Y
T
N
Y
L
M
Q
I
M
F
S
L
M
M
I
G
N
I
L
N
F
I
V
---
R
A
S
A
S
A
K
R
V
L
E
V
L
N
E
K
P
A
I
E
E
A
D
N
----
A
-
L
A
L
P
N
V
----
E
G
S
V
S
F
E
N
V
E
F
R
Y
-
F
E
N
-
T
-
D
P
V
L
S
G
V
N
F
S
V
K
P
G
S
L
V
A
V
L
G
E
T
G
S
G
K
S
T
L
M
N
L
I
P
R
L
I
D
P
E
---
R
---
G
R
V
E
V
D
E
L
D
V
R
T
V
K
L
K
D
L
R
G
H
I
S
A
V
P
Q
E
T
V
L
F
S
G
T
I
K
E
N
L
---
K
W
G
R
E
-
D
---
A
T
D
D
E
I
V
E
A
A
K
I
A
Q
I
H
D
F
I
I
S
L
P
E
G
Y
D
S
R
V
E
R
G
G
R
N
F
S
G
G
Q
K
Q
R
L
S
I
A
R
A
L
V
K
K
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L
I
L
D
D
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T
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K
R
I
L
D
G
L
K
R
Y
T
--
K
G
--
C
T
T
F
I
I
T
Q
K
I
P
T
A
L
L
A
D
K
I
L
V
L
H
E
G
K
V
A
G
F
G
T
H
K
E
L
--
L
E
H
--
C
K
P
Y
R
E
I
Y
E
S
Q
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
87.96
33%
-102
- C1 -
4Q4H
-
?
A:
[22-579]
-----------------------------------------------------------------------------------------
W
I
F
A
V
---
L
A
P
L
F
M
V
V
E
V
I
C
D
L
S
Q
P
T
L
L
A
R
I
V
D
E
G
I
A
R
G
------
D
--
F
S
L
V
L
K
T
----
G
I
L
M
L
-------
I
V
A
L
I
G
A
V
G
G
I
G
C
T
V
F
A
S
Y
A
S
Q
N
F
G
A
D
L
R
R
D
L
F
R
K
V
L
S
F
S
I
S
N
V
N
R
F
H
T
S
S
L
I
T
R
L
T
N
D
V
T
Q
L
Q
----
N
L
V
M
M
L
L
R
I
V
V
R
A
P
L
L
F
V
G
G
I
V
M
A
V
S
I
N
V
K
L
S
S
V
L
I
F
L
I
P
P
I
V
L
L
F
V
W
L
T
K
K
G
----
N
P
L
F
---------
R
-----
K
I
----
Q
E
S
T
D
E
V
N
R
V
V
R
E
N
L
L
G
V
R
V
-
V
R
A
F
R
R
E
E
Y
E
N
E
N
F
R
K
A
N
E
S
L
-------
R
R
S
I
I
S
A
F
S
L
I
V
F
A
L
P
L
-
F
I
F
I
V
N
M
G
M
I
A
V
-
L
W
F
G
G
V
L
V
R
N
----------------------
N
Q
M
E
I
G
S
I
M
A
-
Y
T
N
Y
L
M
Q
I
M
F
S
L
M
M
I
G
N
I
L
N
F
I
V
---
R
A
S
A
S
A
K
R
V
L
E
V
L
N
E
K
P
A
I
E
E
A
D
N
----
A
-
L
A
L
P
N
V
----
E
G
S
V
S
F
E
N
V
E
F
R
Y
-
F
E
N
-
T
-
D
P
V
L
S
G
V
N
F
S
V
K
P
G
S
L
V
A
V
L
G
E
T
G
S
G
K
S
T
L
M
N
L
I
P
R
L
I
D
P
E
---
R
---
G
R
V
E
V
D
E
L
D
V
R
T
V
K
L
K
D
L
R
G
H
I
S
A
V
P
Q
E
T
V
L
F
S
G
T
I
K
E
N
L
---
K
W
G
R
E
-
D
---
A
T
D
D
E
I
V
E
A
A
K
I
A
Q
I
H
D
F
I
I
S
L
P
E
G
Y
D
S
R
V
E
R
G
G
R
N
F
S
G
G
Q
K
Q
R
L
S
I
A
R
A
L
V
K
K
P
K
V
L
I
L
D
D
C
T
S
S
V
D
P
I
T
E
K
R
I
L
D
G
L
K
R
Y
T
--
K
G
--
C
T
T
F
I
I
T
Q
K
I
P
T
A
L
L
A
D
K
I
L
V
L
H
E
G
K
V
A
G
F
G
T
H
K
E
L
--
L
E
H
--
C
K
P
Y
R
E
I
Y
E
S
Q
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
86.92
33%
-101
- C1 -
4Q4J
-
?
A:
[22-579]
-----------------------------------------------------------------------------------------
W
I
F
A
V
---
L
A
P
L
F
M
V
V
E
V
I
S
D
L
S
Q
P
T
L
L
A
R
I
V
D
E
G
I
A
R
G
------
D
--
F
S
L
V
L
K
T
----
G
I
L
M
L
-------
I
V
A
L
I
G
A
V
G
G
I
G
S
T
V
F
A
S
Y
A
S
Q
N
F
G
A
D
L
R
R
D
L
F
R
K
V
L
S
F
S
I
S
N
V
N
R
F
H
T
S
S
L
I
T
R
L
T
N
D
V
T
Q
L
Q
----
N
L
V
M
M
L
L
R
I
V
V
R
A
P
L
L
F
V
G
G
I
V
M
A
V
S
I
N
V
K
L
S
S
V
L
I
F
L
I
P
P
I
V
L
L
F
V
W
L
T
K
K
G
----
N
P
L
F
---------
R
-----
K
I
----
Q
E
S
T
D
E
V
N
R
V
V
R
E
N
L
L
G
V
R
V
-
V
R
A
F
R
R
E
E
Y
E
N
E
N
F
R
K
A
N
E
S
L
-------
R
R
S
I
I
S
A
F
S
L
I
V
F
A
L
P
L
-
F
I
F
I
V
N
M
G
M
I
A
V
-
L
W
F
G
G
V
L
V
R
N
----------------------
N
Q
M
E
I
G
S
I
M
A
-
Y
T
N
Y
L
M
Q
I
M
F
S
L
M
M
I
G
N
I
L
N
F
I
V
---
R
A
S
A
S
A
K
R
V
L
E
V
L
N
E
K
P
A
I
E
E
A
D
N
----
A
-
L
A
L
P
N
V
----
E
G
S
V
S
F
E
N
V
E
F
R
Y
-
F
E
N
-
T
-
D
P
V
L
S
G
V
N
F
S
V
K
P
G
S
L
V
A
V
L
G
E
T
G
S
G
K
S
T
L
M
N
L
I
P
R
L
I
D
P
E
---
R
---
G
R
V
E
V
D
E
L
D
V
R
T
V
K
L
K
D
L
R
G
H
I
S
A
V
P
Q
E
T
V
L
F
S
G
T
I
K
E
N
L
---
K
W
G
R
E
-
D
---
A
T
D
D
E
I
V
E
A
A
K
I
A
Q
I
H
D
F
I
I
S
L
P
E
G
Y
D
S
R
V
E
R
G
G
R
N
F
S
G
G
Q
K
Q
R
L
S
I
A
R
A
L
V
K
K
P
K
V
L
I
L
D
D
S
T
C
S
V
D
P
I
T
E
K
R
I
L
D
G
L
K
R
Y
T
--
K
G
--
S
T
T
F
I
I
T
Q
K
I
P
T
A
L
L
A
D
K
I
L
V
L
H
E
G
K
V
A
G
F
G
T
H
K
E
L
--
L
E
H
--
S
K
P
Y
R
E
I
Y
E
S
Q
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
77.70
27%
-100
- C1 -
3B60
2
MSBA_SALTY
A:
[13-581]
---------------------------------------------------------------------------------
F
R
R
L
----
W
P
T
I
A
PFK
A
G
L
I
V
A
G
I
A
L
I
L
N
A
A
S
D
T
F
M
L
S
L
L
K
P
L
L
D
D
G
FGKT
D
-
R
--
S
V
L
L
W
M
P
L
V
V
I
G
L
-
M
I
L
R
G
I
T
S
Y
I
S
S
Y
C
--
I
S
W
V
S
G
K
V
V
M
T
M
R
R
R
-----
L
----
F
G
H
M
M
G
M
P
V
A
F
F
D
K
Q
S
T
G
T
L
L
S
R
I
T
Y
D
S
E
Q
V
A
----
S
S
S
S
G
A
L
I
T
V
V
R
E
G
A
S
I
I
G
L
F
I
M
M
F
Y
Y
S
W
Q
----
L
S
I
I
L
V
V
L
A
P
I
V
S
I
A
I
R
V
V
----
S
K
R
F
---------
R
-----
S
I
S
K
N
M
Q
N
T
M
G
Q
V
T
T
S
A
E
Q
M
L
K
G
H
K
E
-
V
L
I
F
G
G
Q
E
V
E
T
K
R
F
D
K
V
S
N
K
M
-------
R
L
Q
G
M
K
M
V
S
A
S
S
I
S
D
P
I
-
I
Q
L
I
A
S
-
L
A
L
A
-------
F
V
L
Y
A
A
S
F
P
--------
S
V
M
D
S
L
T
A
G
T
I
T
V
-
V
F
S
S
M
I
A
L
----
M
R
P
L
K
S
L
T
N
V
N
A
Q
F
---
Q
---
R
G
M
A
A
C
Q
T
L
F
A
I
L
D
--
S
E
Q
E
K
D
E
G
----
K
-
R
V
I
D
R
A
----
T
G
D
L
E
F
R
N
V
T
F
T
Y
-
P
G
R
-
E
-
V
P
A
L
R
N
I
N
L
K
I
P
A
G
K
T
V
A
L
V
G
R
S
G
S
G
K
S
T
I
A
S
L
I
T
R
F
Y
D
I
D
---
E
---
G
H
I
L
M
D
G
H
D
L
R
E
Y
T
L
A
S
L
R
N
Q
V
A
L
V
S
Q
N
V
H
L
F
N
D
T
V
A
N
N
I
A
Y
A
R
T
--
E
-
E
---
Y
S
R
E
Q
I
E
E
A
A
R
M
A
Y
A
M
D
F
I
N
K
M
D
N
G
L
D
T
I
I
G
E
N
G
V
L
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
L
R
D
S
P
I
L
I
L
D
E
A
T
S
A
L
D
T
E
S
E
R
A
I
Q
A
A
L
D
E
L
Q
--
K
N
--
R
T
S
L
V
I
A
H
R
L
S
T
I
E
Q
A
D
E
I
V
V
V
E
D
G
I
I
V
E
R
G
T
H
S
E
L
--
L
A
Q
--
H
G
V
Y
A
Q
L
H
K
M
Q
F
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
83
HHSearch
76.93
26%
-97
- C1 -
3WMG
6
?
A:
[16-598]
-------------------------------------------------------------------------------
R
I
F
A
L
A
W
S
S
S
A
T
M
I
V
---
I
G
F
I
A
S
I
L
E
G
A
T
L
P
A
F
A
I
V
F
G
R
M
F
Q
V
F
T
K
S
K
----
S
Q
I
--
E
G
E
T
W
K
Y
----
S
V
G
F
V
G
I
G
V
F
E
F
I
V
A
G
S
--
R
T
A
L
F
G
I
A
S
E
R
L
A
R
D
-----
L
R
V
A
A
F
S
N
L
V
E
Q
D
V
T
Y
F
D
R
R
K
A
G
E
L
G
G
K
L
N
N
D
V
Q
V
I
Q
----
Y
S
F
S
K
L
G
-
A
V
L
F
N
L
A
Q
C
V
V
G
I
I
V
A
F
I
F
A
P
A
L
T
G
V
L
I
A
L
S
P
L
V
V
L
A
V
V
V
Q
M
I
E
M
----
S
G
N
T
---------
K
-----
R
S
----
S
E
A
Y
A
S
A
G
S
V
A
A
E
V
F
S
N
I
R
T
-
T
K
A
F
E
A
E
R
Y
E
T
Q
R
Y
G
S
K
L
D
P
L
-------
Y
R
L
G
R
R
R
Y
I
S
D
G
L
F
F
G
L
-
S
M
L
V
I
F
C
V
Y
A
L
A
-
L
W
W
G
G
Q
L
I
A
R
G
S
L
N
-----------------------
L
G
N
L
L
T
A
F
F
S
A
I
L
G
F
M
G
V
G
Q
A
A
Q
V
W
P
D
V
T
---
R
G
L
G
A
G
G
E
L
F
A
M
I
D
R
V
P
Q
Y
R
R
P
D
P
G
A
E
V
V
-
T
Q
P
L
V
L
----
K
Q
G
I
V
F
E
N
V
H
F
R
Y
-
P
T
R
M
N
-
V
E
V
L
R
G
I
S
L
T
I
P
N
G
K
T
V
A
I
V
G
G
S
G
A
G
K
S
T
I
I
Q
L
L
M
R
F
Y
D
I
E
PQG
G
---
G
L
L
L
F
D
G
T
P
A
W
N
Y
D
F
H
A
L
R
S
Q
I
G
L
V
S
Q
E
P
V
L
F
S
G
T
I
R
D
N
I
L
Y
G
---
K
R
-
D
---
A
T
D
E
E
V
I
Q
A
L
R
E
A
N
A
Y
S
F
V
M
A
L
P
D
G
L
D
T
E
V
G
E
R
G
L
A
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
I
L
K
H
P
T
L
L
C
L
D
E
S
T
S
A
L
D
A
E
S
E
A
L
V
Q
E
A
L
D
R
M
M
A
S
D
G
--
V
T
S
V
V
I
A
H
R
L
S
T
V
A
R
A
D
L
I
L
V
M
Q
D
G
V
V
V
E
Q
G
N
H
S
E
L
--
M
A
L
GP
S
G
F
Y
Y
Q
L
V
E
K
Q
L
A
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
81
HHSearch
76.37
26%
-97
- C1 -
3ZDQ
6
ABCBA_HUMAN
A:
[12-572]
-----------------------------------------------------------------------------------
G
L
A
Y
P
E
R
R
R
L
A
---
A
A
V
G
F
L
T
M
S
S
V
I
S
M
S
A
P
F
F
L
G
K
I
I
D
V
I
Y
T
N
P
----
T
-
V
DY
S
D
N
L
T
R
L
----
C
L
G
L
S
A
V
F
L
C
G
A
A
A
N
A
I
--
R
V
Y
L
M
Q
T
S
G
Q
R
I
V
N
R
-----
L
R
T
S
L
F
S
S
I
L
R
Q
E
V
A
F
F
D
K
T
R
T
G
E
L
I
N
R
L
S
S
D
T
A
L
L
G
----
R
S
V
T
E
N
L
S
D
G
L
R
A
G
A
Q
A
S
V
G
I
S
M
M
F
F
V
S
P
N
L
A
T
F
V
L
S
V
V
P
P
V
S
I
I
A
V
I
Y
G
R
Y
L
----
R
K
L
T
---------
K
-----
V
T
----
Q
D
S
L
A
Q
A
T
Q
L
A
E
E
R
I
G
N
V
R
T
-
V
R
A
F
G
K
E
M
T
E
I
E
K
Y
A
S
K
V
D
H
V
-------
M
Q
L
A
R
K
E
A
F
A
R
A
G
F
F
G
A
-
T
G
L
S
G
N
L
I
V
L
S
V
-
L
Y
K
G
G
L
L
M
G
S
A
H
M
T
-----------------------
V
G
E
L
S
S
F
L
M
Y
A
F
W
V
G
I
S
I
G
G
L
S
S
F
Y
S
E
L
M
---
K
G
L
G
A
G
G
R
L
W
E
L
L
E
R
E
P
K
L
P
F
N
E
G
----
V
I
L
N
E
K
S
F
----
Q
G
A
L
E
F
K
N
V
H
F
A
Y
-
P
A
R
P
E
-
V
P
I
F
Q
D
F
S
L
S
I
P
S
G
S
V
T
A
L
V
G
P
S
G
S
G
K
S
T
V
L
S
L
L
L
R
L
Y
D
P
A
---
S
---
G
T
I
S
L
D
G
H
D
I
R
Q
L
N
P
V
W
L
R
S
K
I
G
T
V
S
Q
E
P
I
L
F
S
C
S
I
A
E
N
I
A
Y
G
---
A
D
-
D
PSS
V
T
A
E
E
I
Q
R
V
A
E
V
A
N
A
V
A
F
I
R
N
F
P
Q
G
F
N
T
V
V
G
E
K
G
V
L
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
L
L
K
N
P
K
I
L
L
L
D
E
A
T
S
A
L
D
A
E
N
E
Y
L
V
Q
E
A
L
D
R
L
M
--
D
G
--
R
T
V
L
V
I
A
H
R
L
S
T
I
K
N
A
N
M
V
A
V
L
D
Q
G
K
I
T
E
Y
G
K
H
E
E
L
--
L
S
K
P---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
101
Fugue
75.70
25%
-93
- C1 -
3B60
2
MSBA_SALTY
A:
[10-581]
---------------------------------------------------------------------------W
Q
T
F
R
R
L
W
P
T
I
A
P
F
K
A
G
L
I
---
V
A
G
I
A
L
I
L
N
A
A
S
D
T
F
M
L
S
L
L
K
P
L
L
D
D
-
G
F
G
K
----
T
-
D
--
R
S
V
L
L
W
M
----
P
L
V
V
I
G
L
M
I
L
R
G
I
T
S
Y
I
--
S
S
Y
C
I
S
W
V
S
G
K
V
V
M
T
-----
M
R
R
R
L
F
G
H
M
M
G
M
P
V
A
F
F
D
K
Q
S
T
G
T
L
L
S
R
I
T
Y
D
S
E
Q
V
A
----
S
S
S
S
G
A
L
I
T
V
V
R
E
G
A
S
I
I
G
L
F
I
M
M
F
Y
Y
S
W
Q
L
S
I
I
L
V
V
L
A
P
I
V
S
I
A
I
R
V
V
S
K
R
F
----
R
S
I
S
---------
K
-----
N
M
----
Q
N
T
M
G
Q
V
T
T
S
A
E
Q
M
L
K
G
H
K
E
-
V
L
I
F
G
G
Q
E
V
E
T
K
R
F
D
K
V
S
N
K
M
-------
R
L
Q
G
M
K
M
V
S
A
S
S
I
S
D
P
I
-
I
Q
L
I
A
S
L
A
L
A
F
V
-
L
Y
A
A
S
F
P
S
V
M
D
S
L
T
-----------------------
A
G
T
I
T
V
V
F
S
S
M
I
A
L
M
R
P
L
K
S
L
T
N
V
N
A
Q
F
Q
---
R
G
M
A
A
C
Q
T
L
F
A
I
L
D
S
E
Q
E
K
--
D
E
G
----
K
-
R
V
I
D
R
A
----
T
G
D
L
E
F
R
N
V
T
F
T
Y
-
P
G
R
-
E
-
V
P
A
L
R
N
I
N
L
K
I
P
A
G
K
T
V
A
L
V
G
R
S
G
S
G
K
S
T
I
A
S
L
I
T
R
F
Y
D
I
D
---
E
---
G
H
I
L
M
D
G
H
D
L
R
E
Y
T
L
A
S
L
R
N
Q
V
A
L
V
S
Q
N
V
H
L
F
N
D
T
V
A
N
N
I
A
Y
A
--
R
T
E
-
E
---
Y
S
R
E
Q
I
E
E
A
A
R
M
A
Y
A
M
D
F
I
N
K
M
D
N
G
L
D
T
I
I
G
E
N
G
V
L
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
L
R
D
S
P
I
L
I
L
D
E
A
T
S
A
L
D
T
E
S
E
R
A
I
Q
A
A
L
D
E
L
Q
--
K
N
--
R
T
S
L
V
I
A
H
R
L
S
T
I
E
Q
A
D
E
I
V
V
V
E
D
G
I
I
V
E
R
G
T
H
S
E
L
--
L
A
Q
--
H
G
V
Y
A
Q
L
H
K
M
Q
F
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
82
HHSearch
74.58
25%
-91
- C1 -
3B60
2
MSBA_SALTY
A:
[21-581]
--------------------------------------------------------------------------------------
A
P
F
K
A
G
L
I
---
V
A
G
I
A
L
I
L
N
A
A
S
D
T
F
M
L
S
L
L
K
P
L
L
D
D
G
F
G
K
T
------
D
--
R
S
V
L
L
W
M
----
P
L
V
V
I
G
L
M
I
L
R
G
I
T
S
Y
I
--
S
S
Y
C
I
S
W
V
S
G
K
V
V
M
T
-----
M
R
R
R
L
F
G
H
M
M
G
M
P
V
A
F
F
D
K
Q
S
T
G
T
L
L
S
R
I
T
Y
D
S
E
Q
V
A
----
S
S
S
S
G
A
L
I
T
V
V
R
E
G
A
S
I
I
G
L
F
I
M
M
F
Y
Y
S
W
Q
L
S
I
I
L
V
V
L
A
P
I
V
S
I
A
I
R
V
V
S
K
R
F
----
R
S
I
S
---------
K
-----
N
M
----
Q
N
T
M
G
Q
V
T
T
S
A
E
Q
M
L
K
G
H
K
E
-
V
L
I
F
G
G
Q
E
V
E
T
K
R
F
D
K
V
S
N
K
M
-------
R
L
Q
G
M
K
M
V
S
A
S
S
I
S
D
P
I
-
I
Q
L
I
A
S
L
A
L
A
F
V
-
L
Y
A
A
S
F
P
S
V
M
D
S
L
T
-----------------------
A
G
T
I
T
V
V
F
S
S
M
I
A
L
M
R
P
L
K
S
L
T
N
V
N
A
Q
F
Q
---
R
G
M
A
A
C
Q
T
L
F
A
I
L
D
S
E
Q
E
K
D
E
G
K
R
-------
V
I
D
R
A
----
T
G
D
L
E
F
R
N
V
T
F
T
Y
-
P
G
R
-
E
-
V
P
A
L
R
N
I
N
L
K
I
P
A
G
K
T
V
A
L
V
G
R
S
G
S
G
K
S
T
I
A
S
L
I
T
R
F
Y
D
I
D
---
E
---
G
H
I
L
M
D
G
H
D
L
R
E
Y
T
L
A
S
L
R
N
Q
V
A
L
V
S
Q
N
V
H
L
F
N
D
T
V
A
N
N
I
A
Y
A
---
R
T
E
E
---
Y
S
R
E
Q
I
E
E
A
A
R
M
A
Y
A
M
D
F
I
N
K
M
D
N
G
L
D
T
I
I
G
E
N
G
V
L
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
L
R
D
S
P
I
L
I
L
D
E
A
T
S
A
L
D
T
E
S
E
R
A
I
Q
A
A
L
D
E
L
Q
--
K
N
--
R
T
S
L
V
I
A
H
R
L
S
T
I
E
Q
A
D
E
I
V
V
V
E
D
G
I
I
V
E
R
G
T
H
S
E
L
--
L
A
Q
--
H
G
V
Y
A
Q
L
H
K
M
Q
F
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
74.31
28%
-99
- C1 -
2HYD
3
Y1866_STAAM
A:
[83-572]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
L
A
Q
W
T
S
N
K
I
L
Y
D
-----
I
R
K
K
L
Y
N
H
L
Q
A
L
S
A
R
F
Y
A
N
N
Q
V
G
Q
V
I
S
R
V
I
N
D
V
E
Q
T
K
----
D
F
I
L
T
G
L
M
N
I
W
L
D
C
I
T
I
I
I
A
L
S
I
M
F
F
L
D
V
K
L
T
--
L
A
A
L
F
I
F
P
F
Y
I
L
T
V
Y
V
F
F
G
R
L
R
K
L
T
R
E
---------
R
S
Q
A
L
A
E
V
----
Q
G
F
L
-------
H
E
R
V
Q
G
I
S
V
-
V
K
S
F
A
I
E
D
N
E
A
K
N
F
D
K
K
N
T
N
F
L
T
R
A
L
K
H
T
R
W
N
A
Y
S
F
A
A
I
N
T
V
T
D
I
-
G
P
I
I
V
I
G
--------
V
G
A
Y
L
-------
A
I
S
G
S
I
T
V
G
T
L
A
A
----------------
F
V
G
Y
L
E
L
L
F
G
P
L
R
R
L
V
A
S
F
T
T
L
T
---
Q
S
F
A
S
M
D
R
V
F
Q
L
I
D
E
D
Y
D
I
K
N
G
V
G
----
A
-
Q
P
I
E
I
K
----
Q
G
R
I
D
I
D
H
V
S
F
Q
Y
-
N
D
N
-
E
-
A
P
I
L
K
D
I
N
L
S
I
E
K
G
E
T
V
A
F
V
G
M
S
G
G
G
K
S
T
L
I
N
L
I
P
R
F
Y
D
V
T
---
S
---
G
Q
I
L
I
D
G
H
N
I
K
D
F
L
T
G
S
L
R
N
Q
I
G
L
V
Q
Q
D
N
I
L
F
S
D
T
V
K
E
N
I
L
L
G
---
R
P
-
T
---
A
T
D
E
E
V
V
E
A
A
K
M
A
N
A
H
D
F
I
M
N
L
P
Q
G
Y
D
T
E
V
G
E
R
G
V
K
L
S
G
G
Q
K
Q
R
L
S
I
A
R
I
F
L
N
N
P
P
I
L
I
L
D
E
A
T
S
A
L
D
L
E
S
E
S
I
I
Q
E
A
L
D
V
L
S
--
K
D
--
R
T
T
L
I
V
A
H
R
L
S
T
I
T
H
A
D
K
I
V
V
I
E
N
G
H
I
V
E
T
G
T
H
R
E
L
--
I
A
K
--
Q
G
A
Y
E
H
L
Y
S
I
Q
N
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
74.15
28%
-99
- C1 -
2ONJ
4
Y1866_STAAM
A:
[83-572]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
L
A
Q
W
T
S
N
K
I
L
Y
D
-----
I
R
K
K
L
Y
N
H
L
Q
A
L
S
A
R
F
Y
A
N
N
Q
V
G
Q
V
I
S
R
V
I
N
D
V
E
Q
T
K
----
D
F
I
L
T
G
L
M
N
I
W
L
D
C
I
T
I
I
I
A
L
S
I
M
F
F
L
D
V
K
L
T
--
L
A
A
L
F
I
F
P
F
Y
I
L
T
V
Y
V
F
F
G
R
L
R
K
L
T
R
E
---------
R
S
Q
A
L
A
E
V
----
Q
G
F
L
-------
H
E
R
V
Q
G
I
S
V
-
V
K
S
F
A
I
E
D
N
E
A
K
N
F
D
K
K
N
T
N
F
L
T
R
A
L
K
H
T
R
W
N
A
Y
S
F
A
A
I
N
T
V
T
D
I
-
G
P
I
I
V
I
G
--------
V
G
A
Y
L
-------
A
I
S
G
S
I
T
V
G
T
L
A
A
----------------
F
V
G
Y
L
E
L
L
F
G
P
L
R
R
L
V
A
S
F
T
T
L
T
---
Q
S
F
A
S
M
D
R
V
F
Q
L
I
D
E
D
Y
D
I
K
N
G
V
G
----
A
-
Q
P
I
E
I
K
----
Q
G
R
I
D
I
D
H
V
S
F
Q
Y
-
N
D
N
-
E
-
A
P
I
L
K
D
I
N
L
S
I
E
K
G
E
T
V
A
F
V
G
M
S
G
G
G
K
S
T
L
I
N
L
I
P
R
F
Y
D
V
T
---
S
---
G
Q
I
L
I
D
G
H
N
I
K
D
F
L
T
G
S
L
R
N
Q
I
G
L
V
Q
Q
D
N
I
L
F
S
D
T
V
K
E
N
I
L
L
G
---
R
P
-
T
---
A
T
D
E
E
V
V
E
A
A
K
M
A
N
A
H
D
F
I
M
N
L
P
Q
G
Y
D
T
E
V
G
E
R
G
V
K
L
S
G
G
Q
K
Q
R
L
S
I
A
R
I
F
L
N
N
P
P
I
L
I
L
D
E
A
T
S
A
L
D
L
E
S
E
S
I
I
Q
E
A
L
D
V
L
S
--
K
D
--
R
T
T
L
I
V
A
H
R
L
S
T
I
T
H
A
D
K
I
V
V
I
E
N
G
H
I
V
E
T
G
T
H
R
E
L
--
I
A
K
--
Q
G
A
Y
E
H
L
Y
S
I
Q
N
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
62.94
31%
-82
- C1 -
3WMG
2
?
A:
[173-598]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
I
A
L
S
P
L
V
V
L
A
----
V
V
V
Q
M
I
E
M
S
G
N
T
K
R
-----
S
S
----
E
A
Y
A
S
A
-
G
S
V
A
A
E
V
F
S
N
I
R
T
-
T
K
A
F
E
A
E
R
Y
E
T
Q
R
Y
G
S
K
L
D
P
L
-------
Y
R
L
G
R
R
R
Y
I
S
D
G
L
F
F
G
L
S
M
L
V
I
F
C
V
Y
A
L
A
L
-
W
W
G
G
Q
-------------------
L
I
A
R
G
S
L
----
N
L
G
N
L
L
T
A
F
F
S
----
A
I
L
G
F
M
G
V
G
Q
A
A
Q
V
W
P
D
V
T
R
G
L
G
A
G
G
E
L
F
A
M
I
D
R
V
P
Q
Y
R
R
P
D
P
----
G
-
A
E
V
V
T
Q
PLVL
K
Q
G
I
V
F
E
N
V
H
F
R
Y
P
T
R
M
-
N
-
V
E
V
L
R
G
I
S
L
T
I
P
N
G
K
T
V
A
I
V
G
G
S
G
A
G
K
S
T
I
I
Q
L
L
M
R
F
Y
D
I
E
---
P
QGG
G
L
L
L
F
D
G
T
P
A
W
N
Y
D
F
H
A
L
R
S
Q
I
G
L
V
S
Q
E
P
V
L
F
S
G
T
I
R
D
N
I
L
Y
G
---
K
R
-
D
---
A
T
D
E
E
V
I
Q
A
L
R
E
A
N
A
Y
S
F
V
M
A
L
P
D
G
L
D
T
E
V
G
E
R
G
L
A
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
I
L
K
H
P
T
L
L
C
L
D
E
S
T
S
A
L
D
A
E
S
E
A
L
V
Q
E
A
L
D
R
M
M
--
A
S
DG
V
T
S
V
V
I
A
H
R
L
S
T
V
A
R
A
D
L
I
L
V
M
Q
D
G
V
V
V
E
Q
G
N
H
S
E
L
M
A
L
G
P
--
S
G
F
Y
Y
Q
L
V
E
K
Q
L
A
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
62.26
31%
-83
- C1 -
3WME
-
?
A:
[173-597]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
I
A
L
S
P
L
V
V
L
A
----
G
A
A
Q
M
I
E
M
S
G
N
T
K
R
-----
S
S
----
E
A
Y
A
S
A
-
G
S
V
A
A
E
V
F
S
N
I
R
T
-
T
K
A
F
E
A
E
R
Y
E
T
Q
R
Y
G
S
K
L
D
P
L
-------
Y
R
L
G
R
R
R
Y
I
S
D
G
L
F
F
G
L
S
M
L
V
I
F
C
V
Y
A
L
A
L
-
W
W
G
G
Q
-------------------
L
I
A
R
G
S
L
----
N
L
G
N
L
L
T
A
F
F
S
----
A
I
L
G
F
M
G
V
G
Q
A
A
Q
V
W
P
D
V
T
R
G
L
G
A
G
G
E
L
F
A
M
I
D
R
V
P
Q
Y
R
R
P
D
P
----
G
-
A
E
V
V
T
Q
PLVL
K
Q
G
I
V
F
E
N
V
H
F
R
Y
P
T
R
M
-
N
-
V
E
V
L
R
G
I
S
L
T
I
P
N
G
K
T
V
A
I
V
G
G
S
G
A
G
K
S
T
I
I
Q
L
L
M
R
F
Y
D
I
E
---
P
QGG
G
L
L
L
F
D
G
T
P
A
W
N
Y
D
F
H
A
L
R
S
Q
I
G
L
V
S
Q
E
P
V
L
F
S
G
T
I
R
D
N
I
L
Y
G
---
K
R
-
D
---
A
T
D
E
E
V
I
Q
A
L
R
E
A
N
A
Y
S
F
V
M
A
L
P
D
G
L
D
T
E
V
G
E
R
G
L
A
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
I
L
K
H
P
T
L
L
C
L
D
E
S
T
S
A
L
D
A
E
S
E
A
L
V
Q
E
A
L
D
R
M
M
--
A
S
DG
V
T
S
V
V
I
A
H
R
L
S
T
V
A
R
A
D
L
I
L
V
M
Q
D
G
V
V
V
E
Q
G
N
H
S
E
L
M
A
L
G
P
--
S
G
F
Y
Y
Q
L
V
E
K
Q
L
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
62.06
28%
-99
- C1 -
4A82
-
Y1866_STAAM
A:
[83-572]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
L
A
Q
W
T
S
N
K
I
L
Y
D
-----
I
R
K
K
L
Y
N
H
L
Q
A
L
S
A
R
F
Y
A
N
N
Q
V
G
Q
V
I
S
R
V
I
N
D
V
E
Q
T
K
----
D
F
I
L
T
G
L
M
N
I
W
L
D
C
I
T
I
I
I
A
L
S
I
M
F
F
L
D
V
K
L
T
--
L
A
A
L
F
I
F
P
F
Y
I
L
T
V
Y
V
F
F
G
R
L
R
K
L
T
R
E
---------
R
S
Q
A
L
A
E
V
----
Q
G
F
L
-------
H
E
R
V
Q
G
I
S
V
-
V
K
S
F
A
I
E
D
N
E
A
K
N
F
D
K
K
N
T
N
F
L
T
R
A
L
K
H
T
R
W
N
A
Y
S
F
A
A
I
N
T
V
T
D
I
-
G
P
I
I
V
I
G
--------
V
G
A
Y
L
-------
A
I
S
G
S
I
T
V
G
T
L
A
A
----------------
F
V
G
Y
L
E
L
L
F
G
P
L
R
R
L
V
A
S
F
T
T
L
T
---
Q
S
F
A
S
M
D
R
V
F
Q
L
I
D
E
D
Y
D
I
K
N
G
V
G
----
A
-
Q
P
I
E
I
K
----
Q
G
R
I
D
I
D
H
V
S
F
Q
Y
-
N
D
N
-
E
-
A
P
I
L
K
D
I
N
L
S
I
E
K
G
E
T
V
A
F
V
G
M
S
G
G
G
K
S
T
L
I
N
L
I
P
R
F
Y
D
V
T
---
S
---
G
Q
I
L
I
D
G
H
N
I
K
D
F
L
T
G
S
L
R
N
Q
I
G
L
V
Q
Q
D
N
I
L
F
S
D
T
V
K
E
N
I
L
L
G
---
R
P
-
T
---
A
T
D
E
E
V
V
E
A
A
K
M
A
N
A
H
D
F
I
M
N
L
P
Q
G
Y
D
T
E
V
G
E
R
G
V
K
L
S
G
G
Q
K
Q
R
L
S
I
A
R
I
F
L
N
N
P
P
I
L
I
L
D
E
A
T
S
A
L
D
L
E
S
E
S
I
I
Q
E
A
L
D
V
L
S
--
K
D
--
R
T
T
L
I
V
A
H
R
L
S
T
I
T
H
A
D
K
I
V
V
I
E
N
G
H
I
V
E
T
G
T
H
R
E
L
--
I
A
K
--
Q
G
A
Y
E
H
L
Y
S
I
Q
N
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
62.05
31%
-80
- C1 -
3WMF
-
?
A:
[173-597]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
I
A
L
S
P
L
V
V
L
A
----
V
V
V
Q
M
I
E
M
S
G
N
T
K
R
-----
S
S
----
E
A
Y
A
S
A
-
G
S
V
A
A
E
V
F
S
N
I
R
T
-
T
K
A
F
E
A
E
R
Y
E
T
Q
R
Y
G
S
K
L
D
P
L
-------
Y
R
L
G
R
R
R
Y
I
S
D
G
L
F
F
G
L
S
M
L
V
I
F
C
V
Y
A
L
A
L
-
W
W
G
G
Q
-------------------
L
I
A
R
G
S
L
----
N
L
G
N
L
L
T
A
F
F
S
----
A
I
L
G
F
M
G
V
G
Q
A
A
Q
V
W
P
D
V
T
R
G
L
G
A
G
G
E
L
F
A
M
I
D
R
V
P
Q
Y
R
R
P
D
P
----
G
-
A
E
V
V
T
Q
PLVL
K
Q
G
I
V
F
E
N
V
H
F
R
Y
P
T
R
M
-
N
-
V
E
V
L
R
G
I
S
L
T
I
P
N
G
K
T
V
A
I
V
G
G
S
G
A
G
K
S
T
I
I
Q
L
L
M
R
F
Y
D
I
E
---
P
QGG
G
L
L
L
F
D
G
T
P
A
W
N
Y
D
F
H
A
L
R
S
Q
I
G
L
V
S
Q
E
P
V
L
F
S
G
T
I
R
D
N
I
L
Y
G
---
K
R
-
D
---
A
T
D
E
E
V
I
Q
A
L
R
E
A
N
A
Y
S
F
V
M
A
L
P
D
G
L
D
T
E
V
G
E
R
G
L
A
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
I
L
K
H
P
T
L
L
C
L
D
E
S
T
S
A
L
D
A
E
S
E
A
L
V
Q
E
A
L
D
R
M
M
--
A
S
DG
V
T
S
V
V
I
A
H
R
L
S
T
V
A
R
A
D
L
I
L
V
M
Q
D
G
V
V
V
E
Q
G
N
H
S
E
L
M
A
L
G
P
--
S
G
F
Y
Y
Q
L
V
E
K
Q
L
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
104
Fugue
61.35
23%
-90
- C1 -
4F4C
3
PGP1_CAEEL
A:
[4-1306]
N
G
S
L
R
Q
S
L
R
T
L
D
S
F
SLA
P
E
D
V
L
K
T
A
I
K
T
V
E
D
Y
EGDNIDSNG
E
I
K
I
TRDEVV
N
K
V
S
I
P
Q
L
Y
RYTT
T
L
E
K
L
L
L
F
I
G
T
L
V
A
V
I
T
G
A
G
L
P
L
M
S
I
L
Q
G
K
---
V
S
Q
A
F
I
N
E
Q
I
V
I
N
N
N
G
S
T
F
L
P
--
T
G
Q
N
Y
T
K
T
----
D
-
F
--
E
H
D
V
M
N
V
----
V
W
S
Y
A
A
M
T
V
G
M
W
A
A
G
Q
I
--
T
V
T
C
Y
L
Y
V
A
E
Q
M
N
N
R
-----
L
R
R
E
F
V
K
S
I
L
R
Q
E
I
S
W
F
D
T
N
H
S
G
T
L
A
T
K
L
F
D
N
L
E
R
V
K
E
G
T
G
D
K
I
G
M
A
F
Q
Y
L
S
Q
F
I
T
G
F
I
V
A
F
T
H
S
W
Q
L
T
L
V
M
L
A
V
T
P
I
Q
A
L
C
G
F
A
I
A
K
S
M
S
T
F
A
----
I
R
E
T
---------
L
-----
R
Y
----
A
K
A
G
K
V
V
E
E
T
I
S
S
I
R
T
V
V
S
L
N
G
L
R
Y
E
L
E
R
Y
S
T
A
V
E
E
A
K
K
A
G
V
-------
L
K
G
L
F
L
G
I
S
F
G
A
M
Q
A
S
N
-
F
I
S
F
A
L
A
F
Y
I
G
V
-
G
W
V
H
D
G
S
L
N
----------------------------
F
G
D
M
L
T
T
F
S
S
V
M
M
G
S
M
A
L
G
L
A
G
P
Q
L
A
V
L
G
---
T
A
Q
G
A
A
S
G
I
Y
E
V
L
D
R
K
P
V
I
D
S
S
S
K
----
A
-
G
R
K
D
M
K
I---
K
G
D
I
T
V
E
N
V
H
F
T
Y
P
S
R
P
-
D
-
V
P
I
L
R
G
M
N
L
R
V
N
A
G
Q
T
V
A
L
V
G
S
S
G
C
G
K
S
T
I
I
S
L
L
L
R
Y
Y
D
V
L
---
K
---
G
K
I
T
I
D
G
V
D
V
R
D
I
N
L
E
F
L
R
K
N
V
A
V
V
S
Q
E
P
A
L
F
N
C
T
I
E
E
N
I
S
L
G
K
E
G
-------
I
T
R
E
E
M
V
A
A
C
K
M
A
N
A
E
K
F
I
K
T
L
P
N
G
Y
N
T
L
V
G
D
R
G
T
Q
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
L
V
R
N
P
K
I
L
L
L
D
E
A
T
S
A
L
D
A
E
S
E
G
I
V
Q
Q
A
L
D
K
A
A
--
K
G
--
R
T
T
I
I
I
A
H
R
L
S
T
I
R
N
A
D
L
I
I
S
C
K
N
G
Q
V
V
E
V
G
D
H
R
A
L
--
M
A
Q
--
Q
G
L
Y
Y
D
L
V
T
A
Q
T
F
T
D
A
V
D
S
A
A
E
GER
I
G
K
D
A
L
S
R
L
K
Q
E
L
E
ENNAQKTN
L
F
E
I
L
Y
H
A
RPH
A
L
S
L
F
I
G
M
S
T
A
T
I
G
G
F
I
Y
P
T
Y
S
V
F
F
T
S
F
M
N
V
F
AGNPADFL
S
Q
G
H
F
W
A
L
M
F
L
V
L
A
A
A
Q
G
I
C
S
F
L
M
T
F
F
M
G
I
A
S
E
S
L
T
R
D
L
R
N
K
L
F
R
N
V
L
S
QHIGFFDSPQNA
S
G
K
I
S
T
R
L
A
T
D
V
P
N
L
R
T
A
I
D
F
R
F
S
T
V
I
T
T
L
V
S
M
V
A
G
I
G
L
A
F
F
Y
G
W
Q
M
A
L
L
I
I
A
I
L
P
I
V
A
F
G
Q
Y
L
R
G
RRFTGKNVKSA
S
E
F
A
D
S
G
K
I
A
I
E
A
I
E
N
V
R
T
V
Q
A
L
AR
E
D
T
F
Y
E
N
F
C
E
K
L
D
I
P
H
K
E
A
I
K
E
A
F
I
Q
G
L
S
Y
G
C
A
S
S
V
L
Y
L
L
N
T
C
A
Y
R
M
G
L
A
L
I
I
TDPPTMQ
P
M
R
V
L
R
V
M
Y
A
I
T
I
S
T
S
TLGFAT
S
Y
F
P
E
Y
A
K
A
T
F
A
G
G
I
I
F
G
M
L
R
KISKIDSLSLAGEKKKLYGK
V
I
F
K
N
V
R
F
A
Y
PERPEIEILK
G
L
S
F
S
V
E
PG
Q
T
L
A
L
V
G
P
S
GCGKST
V
V
A
L
L
E
RFYDTL
G
G
E
I
F
I
DGSEIKTLN
P
E
H
T
R
S
Q
I
A
I
V
S
Q
E
P
T
L
F
DCS
I
A
E
N
I
I
YGLDPSSVT
M
A
Q
V
E
E
A
A
R
L
A
NI
H
N
F
I
A
E
LPEGFETRVGDRGTQLS
G
G
Q
K
Q
R
I
A
I
A
R
A
L
V
R
NPK
I
L
L
L
D
EATSALDT
E
S
E
K
V
V
Q
E
A
L
D
R
A
R
EG
R
T
C
I
V
I
A
HRLNTVMNAD
C
I
A
V
V
S
NGTII
E
K
G
T
H
T
Q
L
M
S
E
K
24
PsiBlast_CBE
59.43
41%
-87
- C1 -
2GHI
4
?
C:
[17-250]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
E
F
S
D
V
N
F
S
Y
-
P
K
Q
-
T
N
H
R
T
L
K
S
I
N
F
F
I
P
S
G
T
T
C
A
L
V
G
H
T
G
S
G
K
S
T
I
A
K
L
L
Y
R
F
Y
D
A
----
E
---
G
D
I
K
I
G
G
K
N
V
N
K
Y
N
R
N
S
I
R
S
I
I
G
I
V
P
Q
D
T
I
L
F
N
E
T
I
K
Y
N
I
L
Y
G
---
K
L
-
D
---
A
T
-
E
E
V
I
K
A
T
K
S
A
Q
L
Y
D
F
I
E
A
L
P
K
K
W
D
T
I
V
G
--
G
M
K
L
--
G
E
R
Q
R
I
A
I
A
R
C
L
L
K
D
P
K
I
V
I
F
D
E
A
T
S
S
L
D
S
K
T
E
Y
L
F
Q
K
A
V
E
D
L
R
--
K
N
--
R
T
L
I
I
I
A
H
R
L
S
T
I
S
S
A
E
S
I
I
L
L
N
K
G
K
I
V
E
K
G
T
H
K
D
L
--
L
K
L
--
N
G
E
Y
A
E
M
W
N
M
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
59.02
29%
-86
- C1 -
4F4C
-
PGP1_CAEEL
A:
[280-653]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
I
S
S
I
R
T
-
V
V
S
L
N
G
L
R
Y
E
L
E
R
Y
S
T
A
V
E
E
A
-------
K
K
A
G
V
L
K
G
L
F
L
G
I
S
F
G
A
-
M
Q
A
-
S
N
F
I
S
F
A
L
A
F
Y
I
G
V
G
W
V
H
D
G
S
L
N
-----------------------
F
G
D
M
L
T
T
F
S
S
V
M
M
G
S
M
A
L
G
L
A
G
P
Q
L
A
V
L
G
---
T
A
Q
G
A
A
S
G
I
Y
E
V
L
D
R
K
P
V
I
D
S
S
S
K
----
A
-
G
R
K
D
M
K
I---
K
G
D
I
T
V
E
N
V
H
F
T
Y
P
S
R
P
-
D
-
V
P
I
L
R
G
M
N
L
R
V
N
A
G
Q
T
V
A
L
V
G
S
S
G
C
G
K
S
T
I
I
S
L
L
L
R
Y
Y
D
V
L
---
K
---
G
K
I
T
I
D
G
V
D
V
R
D
I
N
L
E
F
L
R
K
N
V
A
V
V
S
Q
E
P
A
L
F
N
C
T
I
E
E
N
I
S
L
G
K
E
G
-------
I
T
R
E
E
M
V
A
A
C
K
M
A
N
A
E
K
F
I
K
T
L
P
N
G
Y
N
T
L
V
G
D
R
G
T
Q
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
L
V
R
N
P
K
I
L
L
L
D
E
A
T
S
A
L
D
A
E
S
E
G
I
V
Q
Q
A
L
D
K
A
A
--
K
G
--
R
T
T
I
I
I
A
H
R
L
S
T
I
R
N
A
D
L
I
I
S
C
K
N
G
Q
V
V
E
V
G
D
H
R
A
L
--
M
A
Q
--
Q
G
L
Y
Y
D
L
V
T
A
Q
T
F
T
D
A
V
D
S
A
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
91
HHSearch
58.40
41%
-82
- C1 -
2GHI
5
?
A:
[15-256]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
V
N
I
E
F
S
D
V
N
F
S
Y
-
P
K
Q
T
N
-
H
R
T
L
K
S
I
N
F
F
I
P
S
G
T
T
C
A
L
V
G
H
T
G
S
G
K
S
T
I
A
K
L
L
Y
R
F
Y
D
A
----
E
---
G
D
I
K
I
G
G
K
N
V
N
K
Y
N
R
N
S
I
R
S
I
I
G
I
V
P
Q
D
T
I
L
F
N
E
T
I
K
Y
N
I
L
Y
G
---
K
L
-
D
---
A
T
D
E
E
V
I
K
A
T
K
S
A
Q
L
Y
D
F
I
E
A
L
P
K
K
W
D
T
I
V
G
N
K
G
M
K
L
S
G
G
E
R
Q
R
I
A
I
A
R
C
L
L
K
D
P
K
I
V
I
F
D
E
A
T
S
S
L
D
S
K
T
E
Y
L
F
Q
K
A
V
E
D
L
R
--
K
N
--
R
T
L
I
I
I
A
H
R
L
S
T
I
S
S
A
E
S
I
I
L
L
N
K
G
K
I
V
E
K
G
T
H
K
D
L
--
L
K
L
--
N
G
E
Y
A
E
M
W
N
M
Q
S
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
58.31
41%
-101
- C1 -
2GHI
1
?
D:
[17-250]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
E
F
S
D
V
N
F
S
Y
-------
H
R
T
L
K
S
I
N
F
F
I
P
S
G
T
T
C
A
L
V
G
H
T
G
S
G
K
S
T
I
A
K
L
L
Y
R
F
Y
D
A
----
E
---
G
D
I
K
I
G
G
K
N
V
N
K
Y
N
R
N
S
I
R
S
I
I
G
I
V
P
Q
D
T
I
L
F
N
E
T
I
K
Y
N
I
L
Y
G
---
K
L
-
D
---
A
T
D
E
E
V
I
K
A
T
K
S
A
Q
L
Y
D
F
I
E
A
L
P
K
K
W
D
T
I
V
------
L
S
G
G
E
R
Q
R
I
A
I
A
R
C
L
L
K
D
P
K
I
V
I
F
D
------
D
S
K
T
E
Y
L
F
Q
K
A
V
E
D
-----
N
--
R
T
L
I
I
I
A
H
R
L
S
T
I
S
S
A
E
S
I
I
L
L
N
K
G
K
I
V
E
K
G
T
H
K
D
L
--
L
K
L
--
N
G
E
Y
A
E
M
W
N
M
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
86
HHSearch
53.70
35%
-80
- C1 -
3VX4
3
?
A:
[29-267]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
F
L
----
D
G
D
I
S
F
E
N
L
S
Y
K
Y
-
G
F
G
---
R
D
T
L
S
D
I
N
L
S
I
K
K
G
S
K
V
S
L
V
G
A
S
G
S
G
K
T
T
L
A
K
L
I
V
N
F
Y
E
P
N
---
K
---
G
I
V
R
I
N
G
N
D
L
K
V
I
D
K
T
A
L
R
R
H
I
S
Y
L
P
Q
Q
A
Y
V
F
S
G
S
I
M
D
N
L
V
L
G
---
A
K
-
E
G--
T
S
Q
E
D
I
I
R
A
C
E
I
A
E
I
R
S
D
I
E
Q
M
P
Q
G
Y
Q
T
E
L
S
D
-
G
A
G
I
S
G
G
Q
K
Q
R
I
A
L
A
R
A
L
L
T
Q
A
P
V
L
I
L
D
A
A
T
S
S
L
D
I
L
T
E
K
K
I
I
S
N
L
L
Q
M
---
T
E
--
K
T
I
I
F
V
A
H
R
L
S
I
S
Q
R
T
D
E
V
I
V
M
D
Q
G
K
I
V
E
Q
G
T
H
K
E
L
--
L
A
K
--
Q
G
F
Y
Y
N
L
F
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
PsiBlast_CBE
52.78
38%
-77
- C1 -
1MV5
3
LMRA_LACLA
A:
[7-240]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
F
A
Y
-
D
-
D
-
S
-
E
Q
I
L
R
D
I
S
F
E
A
Q
P
N
S
I
I
A
F
A
G
P
S
G
G
G
K
S
T
I
F
S
L
L
E
R
F
Y
Q
P
T
---
A
---
G
E
I
T
I
D
G
Q
P
I
D
N
I
S
L
E
N
W
R
S
Q
I
G
F
V
S
Q
D
S
A
I
M
A
G
T
I
R
E
N
L
T
Y
G
L
E
G
---
D
---
Y
T
D
E
D
L
W
Q
V
L
D
L
A
F
A
R
S
F
V
E
N
M
P
D
Q
L
N
T
E
V
G
E
R
G
V
K
I
S
G
G
Q
R
Q
R
L
A
I
A
R
A
F
L
R
N
P
K
I
L
M
L
D
E
A
T
A
S
L
D
S
E
S
E
S
M
V
Q
K
A
L
D
S
L
M
--
K
G
--
R
T
T
L
V
I
A
H
R
L
S
T
I
V
D
A
D
K
I
Y
F
I
E
K
G
Q
I
T
G
S
G
K
H
N
E
L
--
V
A
T
--
H
P
L
Y
A
K
Y
V
S
E
Q
L
T
V
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
51.84
38%
-75
- C1 -
1MV5
3
LMRA_LACLA
C:
[7-240]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
F
A
Y
-
D
-
D
-
S
-
E
Q
I
L
R
D
I
S
F
E
A
Q
P
N
S
I
I
A
F
A
G
P
S
G
G
G
K
S
T
I
F
S
L
L
E
R
F
Y
Q
P
T
---
A
---
G
E
I
T
I
D
G
Q
P
I
D
N
I
S
L
E
N
W
R
S
Q
I
G
F
V
S
Q
D
S
A
I
M
A
G
T
I
R
E
N
L
T
Y
G
L
E
G
---
D
---
Y
T
D
E
D
L
W
Q
V
L
D
L
A
F
A
R
S
F
V
E
N
M
P
D
Q
L
N
T
E
V
G
E
R
G
V
K
I
S
G
G
Q
R
Q
R
L
A
I
A
R
A
F
L
R
N
P
K
I
L
M
L
D
E
A
T
A
S
L
D
S
E
S
E
S
M
V
Q
K
A
L
D
S
L
M
--
K
G
--
R
T
T
L
V
I
A
H
R
L
S
T
I
V
D
A
D
K
I
Y
F
I
E
K
G
Q
I
T
G
S
G
K
H
N
E
L
--
V
A
T
--
H
P
L
Y
A
K
Y
V
S
E
Q
L
T
V
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
51.26
38%
-70
- C1 -
1MV5
2
LMRA_LACLA
B:
[7-240]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
F
A
Y
-
D
-
D
-
S
-
E
Q
I
L
R
D
I
S
F
E
A
Q
P
N
S
I
I
A
F
A
G
P
S
G
G
G
K
S
T
I
F
S
L
L
E
R
F
Y
Q
P
T
---
A
---
G
E
I
T
I
D
G
Q
P
I
D
N
I
S
L
E
N
W
R
S
Q
I
G
F
V
S
Q
D
S
A
I
M
A
G
T
I
R
E
N
L
T
Y
G
L
E
G
---
D
---
Y
T
D
E
D
L
W
Q
V
L
D
L
A
F
A
R
S
F
V
E
N
M
P
D
Q
L
N
T
E
V
G
E
R
G
V
K
I
S
G
G
Q
R
Q
R
L
A
I
A
R
A
F
L
R
N
P
K
I
L
M
L
D
E
A
T
A
S
L
D
S
E
S
E
S
M
V
Q
K
A
L
D
S
L
M
--
K
G
--
R
T
T
L
V
I
A
H
R
L
S
T
I
V
D
A
D
K
I
Y
F
I
E
K
G
Q
I
T
G
S
G
K
H
N
E
L
--
V
A
T
--
H
P
L
Y
A
K
Y
V
S
E
Q
L
T
V
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
44.82
38%
-66
- C1 -
1MV5
3
D:
[7-240]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
F
A
Y
-
D
-
D
-
S
-
E
Q
I
L
R
D
I
S
F
E
A
Q
P
N
S
I
I
A
F
A
G
P
S
G
G
G
K
S
T
I
F
S
L
L
E
R
F
Y
Q
P
T
---
A
---
G
E
I
T
I
D
G
Q
P
I
D
N
I
S
L
E
N
W
R
S
Q
I
G
F
V
S
Q
D
S
A
I
M
A
G
T
I
R
E
N
L
T
Y
G
L
E
G
---
D
---
Y
T
D
E
D
L
W
Q
V
L
D
L
A
F
A
R
S
F
V
E
N
M
P
D
Q
L
N
T
E
V
G
E
R
G
V
K
I
S
G
G
Q
R
Q
R
L
A
I
A
R
A
F
L
R
N
P
K
I
L
M
L
D
E
A
T
A
S
L
D
S
E
S
E
S
M
V
Q
K
A
L
D
S
L
M
--
K
G
--
R
T
T
L
V
I
A
H
R
L
S
T
I
V
D
A
D
K
I
Y
F
I
E
K
G
Q
I
T
G
S
G
K
H
N
E
L
--
V
A
T
--
H
P
L
Y
A
K
Y
V
S
E
Q
L
T
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------